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PMC:1713256 / 28149-29246 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T6853 0-5 NNS denotes Genes
T6854 31-39 VBP denotes continue
T6855 6-10 JJ denotes such
T6856 11-13 IN denotes as
T6857 14-18 NN denotes Msx2
T6858 19-20 -LRB- denotes (
T6859 27-29 NN denotes 3N
T6860 20-26 NN denotes Figure
T6861 29-30 -RRB- denotes )
T6862 40-42 TO denotes to
T6863 46-55 VBN denotes expressed
T6864 43-45 VB denotes be
T6865 56-66 IN denotes throughout
T6866 67-70 DT denotes the
T6867 90-100 NN denotes mesenchyme
T6868 71-80 JJ denotes posterior
T6869 81-89 NN denotes forelimb
T6870 100-102 , denotes ,
T6871 102-112 VBG denotes indicating
T6872 113-117 IN denotes that
T6873 148-150 VBZ denotes is
T6874 118-121 DT denotes the
T6875 141-147 NN denotes tissue
T6876 122-131 JJ denotes posterior
T6877 132-140 NN denotes forelimb
T6878 151-157 JJ denotes viable
T6879 158-160 IN denotes at
T6880 161-166 NN denotes E12.5
T6881 167-169 IN denotes in
T6882 170-173 DT denotes the
T6883 202-209 NNS denotes animals
T6884 174-179 NN denotes Bmp2C
T6885 180-181 NN denotes C
T6886 179-180 HYPH denotes /
T6887 181-182 : denotes ;
T6888 183-188 NN denotes Bmp4C
T6889 189-190 NN denotes C
T6890 188-189 HYPH denotes /
T6891 190-191 : denotes ;
T6892 192-196 NN denotes Prx1
T6893 198-201 NN denotes cre
T6894 196-197 HYPH denotes :
T6895 197-198 HYPH denotes :
T6896 209-210 . denotes .
T6897 210-393 sentence denotes Msx2 is normally expressed in the non-chondrogenic interdigital mesenchyme at this stage (Figure 3M), a continuation of an earlier expression domain throughout the distal mesenchyme.
T6898 211-215 NN denotes Msx2
T6899 228-237 VBN denotes expressed
T6900 216-218 VBZ denotes is
T6901 219-227 RB denotes normally
T6902 238-240 IN denotes in
T6903 241-244 DT denotes the
T6904 275-285 NN denotes mesenchyme
T6905 245-261 JJ denotes non-chondrogenic
T6906 262-274 JJ denotes interdigital
T6907 286-288 IN denotes at
T6908 289-293 DT denotes this
T6909 294-299 NN denotes stage
T6910 300-301 -LRB- denotes (
T6911 308-310 NN denotes 3M
T6912 301-307 NN denotes Figure
T6913 310-311 -RRB- denotes )
T6914 311-313 , denotes ,
T6915 313-314 DT denotes a
T6916 315-327 NN denotes continuation
T6917 328-330 IN denotes of
T6918 331-333 DT denotes an
T6919 353-359 NN denotes domain
T6920 334-341 JJR denotes earlier
T6921 342-352 NN denotes expression
T6922 360-370 IN denotes throughout
T6923 371-374 DT denotes the
T6924 382-392 NN denotes mesenchyme
T6925 375-381 JJ denotes distal
T6926 392-393 . denotes .
T6927 393-525 sentence denotes This expression of Msx2 in the posterior of the BMP2, BMP4–deficient forelimbs reflects a failure of chondrogenesis in this region.
T6928 394-398 DT denotes This
T6929 399-409 NN denotes expression
T6930 473-481 VBZ denotes reflects
T6931 410-412 IN denotes of
T6932 413-417 NN denotes Msx2
T6933 418-420 IN denotes in
T6934 421-424 DT denotes the
T6935 425-434 NN denotes posterior
T6936 435-437 IN denotes of
T6937 438-441 DT denotes the
T6938 463-472 NNS denotes forelimbs
T6939 442-446 NN denotes BMP2
T6940 448-452 NN denotes BMP4
T6941 446-448 , denotes ,
T6942 453-462 JJ denotes deficient
T6943 452-453 HYPH denotes –
T6944 482-483 DT denotes a
T6945 484-491 NN denotes failure
T6946 492-494 IN denotes of
T6947 495-509 NN denotes chondrogenesis
T6948 510-512 IN denotes in
T6949 513-517 DT denotes this
T6950 518-524 NN denotes region
T6951 524-525 . denotes .
T6952 525-839 sentence denotes The loss of the posterior forelimb digits in these mice thus does not appear to represent a decrease in polarizing activity leading to a change in digit identity rather a consequence of the overall level of BMP signaling falling below a threshold for initiating chondrogenesis in the posterior of these forelimbs.
T6953 526-529 DT denotes The
T6954 530-534 NN denotes loss
T6955 596-602 VB denotes appear
T6956 535-537 IN denotes of
T6957 538-541 DT denotes the
T6958 561-567 NNS denotes digits
T6959 542-551 JJ denotes posterior
T6960 552-560 NN denotes forelimb
T6961 568-570 IN denotes in
T6962 571-576 DT denotes these
T6963 577-581 NNS denotes mice
T6964 582-586 RB denotes thus
T6965 587-591 VBZ denotes does
T6966 592-595 RB denotes not
T6967 603-605 TO denotes to
T6968 606-615 VB denotes represent
T6969 616-617 DT denotes a
T6970 618-626 NN denotes decrease
T6971 627-629 IN denotes in
T6972 630-640 VBG denotes polarizing
T6973 641-649 NN denotes activity
T6974 650-657 VBG denotes leading
T6975 658-660 IN denotes to
T6976 661-662 DT denotes a
T6977 663-669 NN denotes change
T6978 670-672 IN denotes in
T6979 673-678 NN denotes digit
T6980 679-687 NN denotes identity
T6981 688-694 RB denotes rather
T6982 697-708 NN denotes consequence
T6983 695-696 DT denotes a
T6984 709-711 IN denotes of
T6985 712-715 DT denotes the
T6986 724-729 NN denotes level
T6987 716-723 JJ denotes overall
T6988 747-754 VBG denotes falling
T6989 730-732 IN denotes of
T6990 733-736 NN denotes BMP
T6991 737-746 NN denotes signaling
T6992 755-760 IN denotes below
T6993 761-762 DT denotes a
T6994 763-772 NN denotes threshold
T6995 773-776 IN denotes for
T6996 777-787 VBG denotes initiating
T6997 788-802 NN denotes chondrogenesis
T6998 803-805 IN denotes in
T6999 806-809 DT denotes the
T7000 810-819 NN denotes posterior
T7001 820-822 IN denotes of
T7002 823-828 DT denotes these
T7003 829-838 NNS denotes forelimbs
T7004 838-839 . denotes .
T7005 839-1097 sentence denotes The posterior of the hindlimb in the mutant, in contrast, appears to remain above this threshold, and more than five digit condensations form in the hindlimb bud (Figures 3K and 1S) and no ectopic expression of Msx2 is observed in the posterior (Figure 3O).
T7006 840-843 DT denotes The
T7007 844-853 JJ denotes posterior
T7008 898-905 VBZ denotes appears
T7009 854-856 IN denotes of
T7010 857-860 DT denotes the
T7011 861-869 NN denotes hindlimb
T7012 870-872 IN denotes in
T7013 873-876 DT denotes the
T7014 877-883 NN denotes mutant
T7015 883-885 , denotes ,
T7016 885-887 IN denotes in
T7017 888-896 NN denotes contrast
T7018 896-898 , denotes ,
T7019 906-908 TO denotes to
T7020 909-915 VB denotes remain
T7021 916-921 IN denotes above
T7022 922-926 DT denotes this
T7023 927-936 NN denotes threshold
T7024 936-938 , denotes ,
T7025 938-941 CC denotes and
T7026 942-946 JJR denotes more
T7027 952-956 CD denotes five
T7028 947-951 IN denotes than
T7029 963-976 NNS denotes condensations
T7030 957-962 NN denotes digit
T7031 977-981 VBP denotes form
T7032 982-984 IN denotes in
T7033 985-988 DT denotes the
T7034 998-1001 NN denotes bud
T7035 989-997 NN denotes hindlimb
T7036 1002-1003 -LRB- denotes (
T7037 1011-1013 NN denotes 3K
T7038 1003-1010 NNS denotes Figures
T7039 1014-1017 CC denotes and
T7040 1018-1020 NN denotes 1S
T7041 1020-1021 -RRB- denotes )
T7042 1022-1025 CC denotes and
T7043 1026-1028 DT denotes no
T7044 1037-1047 NN denotes expression
T7045 1029-1036 JJ denotes ectopic
T7046 1059-1067 VBN denotes observed
T7047 1048-1050 IN denotes of
T7048 1051-1055 NN denotes Msx2
T7049 1056-1058 VBZ denotes is
T7050 1068-1070 IN denotes in
T7051 1071-1074 DT denotes the
T7052 1075-1084 JJ denotes posterior
T7053 1085-1086 -LRB- denotes (
T7054 1093-1095 NN denotes 3O
T7055 1086-1092 NN denotes Figure
T7056 1095-1096 -RRB- denotes )
T7057 1096-1097 . denotes .
R4458 T6853 T6854 nsubj Genes,continue
R4459 T6855 T6856 amod such,as
R4460 T6856 T6853 prep as,Genes
R4461 T6857 T6856 pobj Msx2,as
R4462 T6858 T6859 punct (,3N
R4463 T6859 T6853 parataxis 3N,Genes
R4464 T6860 T6859 compound Figure,3N
R4465 T6861 T6859 punct ),3N
R4466 T6862 T6863 aux to,expressed
R4467 T6863 T6854 xcomp expressed,continue
R4468 T6864 T6863 auxpass be,expressed
R4469 T6865 T6863 prep throughout,expressed
R4470 T6866 T6867 det the,mesenchyme
R4471 T6867 T6865 pobj mesenchyme,throughout
R4472 T6868 T6867 amod posterior,mesenchyme
R4473 T6869 T6867 compound forelimb,mesenchyme
R4474 T6870 T6863 punct ", ",expressed
R4475 T6871 T6863 advcl indicating,expressed
R4476 T6872 T6873 mark that,is
R4477 T6873 T6871 ccomp is,indicating
R4478 T6874 T6875 det the,tissue
R4479 T6875 T6873 nsubj tissue,is
R4480 T6876 T6877 amod posterior,forelimb
R4481 T6877 T6875 compound forelimb,tissue
R4482 T6878 T6873 acomp viable,is
R4483 T6879 T6873 prep at,is
R4484 T6880 T6879 pobj E12.5,at
R4485 T6881 T6873 prep in,is
R4486 T6882 T6883 det the,animals
R4487 T6883 T6881 pobj animals,in
R4488 T6884 T6885 nmod Bmp2C,C
R4489 T6885 T6883 nmod C,animals
R4490 T6886 T6885 punct /,C
R4491 T6887 T6885 punct ;,C
R4492 T6888 T6889 compound Bmp4C,C
R4493 T6889 T6885 appos C,C
R4494 T6890 T6889 punct /,C
R4495 T6891 T6885 punct ;,C
R4496 T6892 T6893 compound Prx1,cre
R4497 T6893 T6885 appos cre,C
R4498 T6894 T6893 punct :,cre
R4499 T6895 T6893 punct :,cre
R4500 T6896 T6854 punct .,continue
R4501 T6898 T6899 nsubjpass Msx2,expressed
R4502 T6900 T6899 auxpass is,expressed
R4503 T6901 T6899 advmod normally,expressed
R4504 T6902 T6899 prep in,expressed
R4505 T6903 T6904 det the,mesenchyme
R4506 T6904 T6902 pobj mesenchyme,in
R4507 T6905 T6904 amod non-chondrogenic,mesenchyme
R4508 T6906 T6904 amod interdigital,mesenchyme
R4509 T6907 T6899 prep at,expressed
R4510 T6908 T6909 det this,stage
R4511 T6909 T6907 pobj stage,at
R4512 T6910 T6911 punct (,3M
R4513 T6911 T6899 parataxis 3M,expressed
R4514 T6912 T6911 compound Figure,3M
R4515 T6913 T6911 punct ),3M
R4516 T6914 T6899 punct ", ",expressed
R4517 T6915 T6916 det a,continuation
R4518 T6916 T6899 npadvmod continuation,expressed
R4519 T6917 T6916 prep of,continuation
R4520 T6918 T6919 det an,domain
R4521 T6919 T6917 pobj domain,of
R4522 T6920 T6919 amod earlier,domain
R4523 T6921 T6919 compound expression,domain
R4524 T6922 T6916 prep throughout,continuation
R4525 T6923 T6924 det the,mesenchyme
R4526 T6924 T6922 pobj mesenchyme,throughout
R4527 T6925 T6924 amod distal,mesenchyme
R4528 T6926 T6899 punct .,expressed
R4529 T6928 T6929 det This,expression
R4530 T6929 T6930 nsubj expression,reflects
R4531 T6931 T6929 prep of,expression
R4532 T6932 T6931 pobj Msx2,of
R4533 T6933 T6929 prep in,expression
R4534 T6934 T6935 det the,posterior
R4535 T6935 T6933 pobj posterior,in
R4536 T6936 T6935 prep of,posterior
R4537 T6937 T6938 det the,forelimbs
R4538 T6938 T6936 pobj forelimbs,of
R4539 T6939 T6940 nmod BMP2,BMP4
R4540 T6940 T6942 npadvmod BMP4,deficient
R4541 T6941 T6940 punct ", ",BMP4
R4542 T6942 T6938 amod deficient,forelimbs
R4543 T6943 T6942 punct –,deficient
R4544 T6944 T6945 det a,failure
R4545 T6945 T6930 dobj failure,reflects
R4546 T6946 T6945 prep of,failure
R4547 T6947 T6946 pobj chondrogenesis,of
R4548 T6948 T6945 prep in,failure
R4549 T6949 T6950 det this,region
R4550 T6950 T6948 pobj region,in
R4551 T6951 T6930 punct .,reflects
R4552 T6953 T6954 det The,loss
R4553 T6954 T6955 nsubj loss,appear
R4554 T6956 T6954 prep of,loss
R4555 T6957 T6958 det the,digits
R4556 T6958 T6956 pobj digits,of
R4557 T6959 T6958 amod posterior,digits
R4558 T6960 T6958 compound forelimb,digits
R4559 T6961 T6954 prep in,loss
R4560 T6962 T6963 det these,mice
R4561 T6963 T6961 pobj mice,in
R4562 T6964 T6955 advmod thus,appear
R4563 T6965 T6955 aux does,appear
R4564 T6966 T6955 neg not,appear
R4565 T6967 T6968 aux to,represent
R4566 T6968 T6955 xcomp represent,appear
R4567 T6969 T6970 det a,decrease
R4568 T6970 T6968 dobj decrease,represent
R4569 T6971 T6970 prep in,decrease
R4570 T6972 T6973 amod polarizing,activity
R4571 T6973 T6971 pobj activity,in
R4572 T6974 T6970 acl leading,decrease
R4573 T6975 T6974 prep to,leading
R4574 T6976 T6977 det a,change
R4575 T6977 T6975 pobj change,to
R4576 T6978 T6977 prep in,change
R4577 T6979 T6980 compound digit,identity
R4578 T6980 T6978 pobj identity,in
R4579 T6981 T6982 advmod rather,consequence
R4580 T6982 T6970 appos consequence,decrease
R4581 T6983 T6982 det a,consequence
R4582 T6984 T6982 prep of,consequence
R4583 T6985 T6986 det the,level
R4584 T6986 T6988 nsubj level,falling
R4585 T6987 T6986 amod overall,level
R4586 T6988 T6984 pcomp falling,of
R4587 T6989 T6986 prep of,level
R4588 T6990 T6991 compound BMP,signaling
R4589 T6991 T6989 pobj signaling,of
R4590 T6992 T6988 prep below,falling
R4591 T6993 T6994 det a,threshold
R4592 T6994 T6992 pobj threshold,below
R4593 T6995 T6994 prep for,threshold
R4594 T6996 T6995 pcomp initiating,for
R4595 T6997 T6996 dobj chondrogenesis,initiating
R4596 T6998 T6996 prep in,initiating
R4597 T6999 T7000 det the,posterior
R4598 T7000 T6998 pobj posterior,in
R4599 T7001 T7000 prep of,posterior
R4600 T7002 T7003 det these,forelimbs
R4601 T7003 T7001 pobj forelimbs,of
R4602 T7004 T6955 punct .,appear
R4603 T7006 T7007 det The,posterior
R4604 T7007 T7008 nsubj posterior,appears
R4605 T7009 T7007 prep of,posterior
R4606 T7010 T7011 det the,hindlimb
R4607 T7011 T7009 pobj hindlimb,of
R4608 T7012 T7008 prep in,appears
R4609 T7013 T7014 det the,mutant
R4610 T7014 T7012 pobj mutant,in
R4611 T7015 T7008 punct ", ",appears
R4612 T7016 T7008 prep in,appears
R4613 T7017 T7016 pobj contrast,in
R4614 T7033 T7034 det the,bud
R4615 T7018 T7008 punct ", ",appears
R4616 T7019 T7020 aux to,remain
R4617 T7034 T7032 pobj bud,in
R4618 T7035 T7034 compound hindlimb,bud
R4619 T7020 T7008 xcomp remain,appears
R4620 T7036 T7037 punct (,3K
R4621 T7037 T7031 parataxis 3K,form
R4622 T7021 T7020 prep above,remain
R4623 T7038 T7037 compound Figures,3K
R4624 T7039 T7037 cc and,3K
R4625 T7040 T7037 conj 1S,3K
R4626 T7022 T7023 det this,threshold
R4627 T7041 T7037 punct ),3K
R4628 T7042 T7031 cc and,form
R4629 T7023 T7021 pobj threshold,above
R4630 T7043 T7044 det no,expression
R4631 T7044 T7046 nsubjpass expression,observed
R4632 T7045 T7044 amod ectopic,expression
R4633 T7046 T7031 conj observed,form
R4634 T7047 T7044 prep of,expression
R4635 T7024 T7008 punct ", ",appears
R4636 T7048 T7047 pobj Msx2,of
R4637 T7049 T7046 auxpass is,observed
R4638 T7050 T7046 prep in,observed
R4639 T7025 T7008 cc and,appears
R4640 T7051 T7052 det the,posterior
R4641 T7052 T7050 pobj posterior,in
R4642 T7026 T7027 amod more,five
R4643 T7053 T7054 punct (,3O
R4644 T7054 T7046 parataxis 3O,observed
R4645 T7027 T7029 nummod five,condensations
R4646 T7055 T7054 compound Figure,3O
R4647 T7056 T7054 punct ),3O
R4648 T7057 T7031 punct .,form
R4649 T7028 T7027 quantmod than,five
R4650 T7029 T7031 nsubj condensations,form
R4651 T7030 T7029 compound digit,condensations
R4652 T7031 T7008 conj form,appears
R4653 T7032 T7031 prep in,form

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T5801 0-5 SO_EXT:0000704 denotes Genes
T5802 14-18 PR_EXT:000010687 denotes Msx2
T5803 46-55 GO:0010467 denotes expressed
T5804 81-100 UBERON:0003859 denotes forelimb mesenchyme
T5805 132-140 UBERON:0002102 denotes forelimb
T5806 141-147 UBERON:0000479 denotes tissue
T5807 174-178 PR_EXT:000000164 denotes Bmp2
T5808 183-187 PR_EXT:000000165 denotes Bmp4
T5809 192-196 PR_EXT:000013316 denotes Prx1
T5810 202-209 NCBITaxon:33208 denotes animals
T5811 211-215 PR_EXT:000010687 denotes Msx2
T5812 228-237 GO:0010467 denotes expressed
T5813 249-261 GO:0051216 denotes chondrogenic
T5814 262-285 UBERON:0009585 denotes interdigital mesenchyme
T5815 342-352 GO:0010467 denotes expression
T5816 382-392 UBERON:0003104 denotes mesenchyme
T5817 399-409 GO:0010467 denotes expression
T5818 413-417 PR_EXT:000010687 denotes Msx2
T5819 442-446 PR_EXT:000000164 denotes BMP2
T5820 448-452 PR_EXT:000000165 denotes BMP4
T5821 463-472 UBERON:0002102 denotes forelimbs
T5822 495-509 GO:0051216 denotes chondrogenesis
T5823 552-567 UBERON:0002389 denotes forelimb digits
T5824 577-581 NCBITaxon:10088 denotes mice
T5825 673-678 UBERON:0002544 denotes digit
T5826 733-736 PR_EXT:000000034 denotes BMP
T5827 733-746 GO:0030509 denotes BMP signaling
T5828 788-802 GO:0051216 denotes chondrogenesis
T5829 829-838 UBERON:0002102 denotes forelimbs
T5830 861-869 UBERON:0002103 denotes hindlimb
T5831 877-883 SO_EXT:sequence_altered_entity denotes mutant
T5832 957-962 UBERON:0002544 denotes digit
T5833 989-1001 UBERON:0005418 denotes hindlimb bud
T5834 1037-1047 GO:0010467 denotes expression
T5835 1051-1055 PR_EXT:000010687 denotes Msx2

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T5597 0-5 SO:0000704 denotes Genes
T5598 14-18 PR:000010687 denotes Msx2
T5599 46-55 GO:0010467 denotes expressed
T5600 81-100 UBERON:0003859 denotes forelimb mesenchyme
T5601 132-140 UBERON:0002102 denotes forelimb
T5602 141-147 UBERON:0000479 denotes tissue
T5603 174-178 PR:000000164 denotes Bmp2
T5604 183-187 PR:000000165 denotes Bmp4
T5605 192-196 PR:000013316 denotes Prx1
T5606 202-209 NCBITaxon:33208 denotes animals
T5607 211-215 PR:000010687 denotes Msx2
T5608 228-237 GO:0010467 denotes expressed
T5609 249-261 GO:0051216 denotes chondrogenic
T5610 262-285 UBERON:0009585 denotes interdigital mesenchyme
T5611 342-352 GO:0010467 denotes expression
T5612 382-392 UBERON:0003104 denotes mesenchyme
T5613 399-409 GO:0010467 denotes expression
T5614 413-417 PR:000010687 denotes Msx2
T5615 442-446 PR:000000164 denotes BMP2
T5616 448-452 PR:000000165 denotes BMP4
T5617 463-472 UBERON:0002102 denotes forelimbs
T5618 495-509 GO:0051216 denotes chondrogenesis
T5619 552-567 UBERON:0002389 denotes forelimb digits
T5620 577-581 NCBITaxon:10088 denotes mice
T5621 673-678 UBERON:0002544 denotes digit
T5622 733-736 PR:000000034 denotes BMP
T5623 733-746 GO:0030509 denotes BMP signaling
T5624 788-802 GO:0051216 denotes chondrogenesis
T5625 829-838 UBERON:0002102 denotes forelimbs
T5626 861-869 UBERON:0002103 denotes hindlimb
T5627 957-962 UBERON:0002544 denotes digit
T5628 989-1001 UBERON:0005418 denotes hindlimb bud
T5629 1037-1047 GO:0010467 denotes expression
T5630 1051-1055 PR:000010687 denotes Msx2