PMC:1647278 / 55972-56373 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1647278","sourcedb":"PMC","sourceid":"1647278","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1647278","text":"As we consider here a binary alphabet (k = 2) and a first order Markov model (m = 1) we have only km(k - 1) = 2 parameters to estimate with a sample of size n = 5000 (so we have 2500 sample per parameter). Although this situation seems quite comfortable, the sensitivity to parameter estimation appears in fact to be so large that we could have a factor 1040 between the true p-value and its estimate.","tracks":[]}