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PMC:1635039 / 614-1141
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T612 | 0-2 | PRP | denotes | We |
T613 | 3-10 | VBD | denotes | deleted |
T614 | 11-14 | DT | denotes | the |
T615 | 37-41 | NN | denotes | Alk5 |
T616 | 15-18 | NN | denotes | TGF |
T617 | 19-20 | NN | denotes | β |
T618 | 18-19 | HYPH | denotes | - |
T619 | 21-25 | NN | denotes | type |
T620 | 26-27 | CD | denotes | I |
T621 | 28-36 | NN | denotes | receptor |
T622 | 42-54 | RB | denotes | specifically |
T623 | 55-57 | IN | denotes | in |
T624 | 58-61 | DT | denotes | the |
T625 | 86-93 | NN | denotes | lineage |
T626 | 62-67 | NN | denotes | mouse |
T627 | 68-74 | JJ | denotes | neural |
T628 | 81-85 | NN | denotes | cell |
T629 | 75-80 | NN | denotes | crest |
T630 | 93-94 | . | denotes | . |
T631 | 94-349 | sentence | denotes | Failure in signaling via ALK5 leads to severe cardiovascular and pharyngeal defects, including inappropriate remodeling of pharyngeal arch arteries, abnormal aortic sac development, failure in pharyngeal organ migration and persistent truncus arteriosus. |
T632 | 95-102 | NN | denotes | Failure |
T633 | 125-130 | VBZ | denotes | leads |
T634 | 103-105 | IN | denotes | in |
T635 | 106-115 | NN | denotes | signaling |
T636 | 116-119 | IN | denotes | via |
T637 | 120-124 | NN | denotes | ALK5 |
T638 | 131-133 | IN | denotes | to |
T639 | 134-140 | JJ | denotes | severe |
T640 | 171-178 | NNS | denotes | defects |
T641 | 141-155 | JJ | denotes | cardiovascular |
T642 | 156-159 | CC | denotes | and |
T643 | 160-170 | JJ | denotes | pharyngeal |
T644 | 178-180 | , | denotes | , |
T645 | 180-189 | VBG | denotes | including |
T646 | 190-203 | JJ | denotes | inappropriate |
T647 | 204-214 | NN | denotes | remodeling |
T648 | 215-217 | IN | denotes | of |
T649 | 218-228 | JJ | denotes | pharyngeal |
T650 | 234-242 | NNS | denotes | arteries |
T651 | 229-233 | NN | denotes | arch |
T652 | 242-244 | , | denotes | , |
T653 | 244-252 | JJ | denotes | abnormal |
T654 | 264-275 | NN | denotes | development |
T655 | 253-259 | JJ | denotes | aortic |
T656 | 260-263 | NN | denotes | sac |
T657 | 275-277 | , | denotes | , |
T658 | 277-284 | NN | denotes | failure |
T659 | 285-287 | IN | denotes | in |
T660 | 288-298 | JJ | denotes | pharyngeal |
T661 | 305-314 | NN | denotes | migration |
T662 | 299-304 | NN | denotes | organ |
T663 | 315-318 | CC | denotes | and |
T664 | 319-329 | JJ | denotes | persistent |
T665 | 338-348 | NN | denotes | arteriosus |
T666 | 330-337 | NN | denotes | truncus |
T667 | 348-349 | . | denotes | . |
T668 | 349-527 | sentence | denotes | While ALK5 is not required for neural crest cell migration, our results demonstrate that it plays an important role in the survival of post-migratory cardiac neural crest cells. |
T669 | 350-355 | IN | denotes | While |
T670 | 368-376 | VBN | denotes | required |
T671 | 356-360 | NN | denotes | ALK5 |
T672 | 361-363 | VBZ | denotes | is |
T673 | 364-367 | RB | denotes | not |
T674 | 422-433 | VBP | denotes | demonstrate |
T675 | 377-380 | IN | denotes | for |
T676 | 381-387 | JJ | denotes | neural |
T677 | 394-398 | NN | denotes | cell |
T678 | 388-393 | NN | denotes | crest |
T679 | 399-408 | NN | denotes | migration |
T680 | 408-410 | , | denotes | , |
T681 | 410-413 | PRP$ | denotes | our |
T682 | 414-421 | NNS | denotes | results |
T683 | 434-438 | IN | denotes | that |
T684 | 442-447 | VBZ | denotes | plays |
T685 | 439-441 | PRP | denotes | it |
T686 | 448-450 | DT | denotes | an |
T687 | 461-465 | NN | denotes | role |
T688 | 451-460 | JJ | denotes | important |
T689 | 466-468 | IN | denotes | in |
T690 | 469-472 | DT | denotes | the |
T691 | 473-481 | NN | denotes | survival |
T692 | 482-484 | IN | denotes | of |
T693 | 485-499 | JJ | denotes | post-migratory |
T694 | 521-526 | NNS | denotes | cells |
T695 | 500-507 | JJ | denotes | cardiac |
T696 | 515-520 | NN | denotes | crest |
T697 | 508-514 | JJ | denotes | neural |
T698 | 526-527 | . | denotes | . |
R100 | T612 | T613 | nsubj | We,deleted |
R101 | T614 | T615 | det | the,Alk5 |
R102 | T615 | T613 | dobj | Alk5,deleted |
R103 | T616 | T617 | nmod | TGF,β |
R104 | T617 | T615 | nmod | β,Alk5 |
R105 | T618 | T617 | punct | -,β |
R106 | T619 | T615 | nmod | type,Alk5 |
R107 | T620 | T619 | nummod | I,type |
R108 | T621 | T615 | compound | receptor,Alk5 |
R109 | T622 | T613 | advmod | specifically,deleted |
R110 | T623 | T613 | prep | in,deleted |
R111 | T624 | T625 | det | the,lineage |
R112 | T625 | T623 | pobj | lineage,in |
R113 | T626 | T625 | nmod | mouse,lineage |
R114 | T627 | T628 | amod | neural,cell |
R115 | T628 | T625 | compound | cell,lineage |
R116 | T629 | T628 | compound | crest,cell |
R117 | T630 | T613 | punct | .,deleted |
R118 | T632 | T633 | nsubj | Failure,leads |
R119 | T634 | T632 | prep | in,Failure |
R120 | T635 | T634 | pobj | signaling,in |
R121 | T636 | T632 | prep | via,Failure |
R122 | T637 | T636 | pobj | ALK5,via |
R123 | T638 | T633 | prep | to,leads |
R124 | T639 | T640 | amod | severe,defects |
R125 | T640 | T638 | pobj | defects,to |
R126 | T641 | T640 | amod | cardiovascular,defects |
R127 | T642 | T641 | cc | and,cardiovascular |
R128 | T643 | T641 | conj | pharyngeal,cardiovascular |
R129 | T644 | T640 | punct | ", ",defects |
R130 | T645 | T640 | prep | including,defects |
R131 | T646 | T647 | amod | inappropriate,remodeling |
R132 | T647 | T645 | pobj | remodeling,including |
R133 | T648 | T647 | prep | of,remodeling |
R134 | T649 | T650 | amod | pharyngeal,arteries |
R135 | T650 | T648 | pobj | arteries,of |
R136 | T651 | T650 | compound | arch,arteries |
R137 | T652 | T647 | punct | ", ",remodeling |
R138 | T653 | T654 | amod | abnormal,development |
R139 | T654 | T647 | appos | development,remodeling |
R140 | T655 | T656 | amod | aortic,sac |
R141 | T656 | T654 | compound | sac,development |
R142 | T657 | T647 | punct | ", ",remodeling |
R143 | T658 | T647 | appos | failure,remodeling |
R144 | T659 | T658 | prep | in,failure |
R145 | T660 | T661 | amod | pharyngeal,migration |
R146 | T661 | T659 | pobj | migration,in |
R147 | T662 | T661 | compound | organ,migration |
R148 | T663 | T661 | cc | and,migration |
R149 | T664 | T665 | amod | persistent,arteriosus |
R150 | T665 | T661 | conj | arteriosus,migration |
R151 | T666 | T665 | compound | truncus,arteriosus |
R152 | T667 | T633 | punct | .,leads |
R153 | T669 | T670 | mark | While,required |
R154 | T670 | T674 | advcl | required,demonstrate |
R155 | T671 | T670 | nsubjpass | ALK5,required |
R156 | T672 | T670 | auxpass | is,required |
R157 | T673 | T670 | neg | not,required |
R158 | T675 | T670 | prep | for,required |
R159 | T676 | T677 | amod | neural,cell |
R160 | T677 | T679 | compound | cell,migration |
R161 | T678 | T677 | compound | crest,cell |
R162 | T679 | T675 | pobj | migration,for |
R163 | T680 | T674 | punct | ", ",demonstrate |
R164 | T681 | T682 | poss | our,results |
R165 | T682 | T674 | nsubj | results,demonstrate |
R166 | T683 | T684 | mark | that,plays |
R167 | T684 | T674 | ccomp | plays,demonstrate |
R168 | T685 | T684 | nsubj | it,plays |
R169 | T686 | T687 | det | an,role |
R170 | T687 | T684 | dobj | role,plays |
R171 | T688 | T687 | amod | important,role |
R172 | T689 | T684 | prep | in,plays |
R173 | T690 | T691 | det | the,survival |
R174 | T691 | T689 | pobj | survival,in |
R175 | T692 | T691 | prep | of,survival |
R176 | T693 | T694 | amod | post-migratory,cells |
R177 | T694 | T692 | pobj | cells,of |
R178 | T695 | T696 | amod | cardiac,crest |
R179 | T696 | T694 | compound | crest,cells |
R180 | T697 | T696 | amod | neural,crest |
R181 | T698 | T674 | punct | .,demonstrate |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T477 | 3-10 | SO_EXT:sequence_deletion_process | denotes | deleted |
T478 | 15-36 | GO_PR_EXT:transforming_growth_factor_beta_receptor_type_I | denotes | TGF-β type I receptor |
T479 | 37-41 | PR_EXT:000000047 | denotes | Alk5 |
T480 | 62-67 | NCBITaxon:10088 | denotes | mouse |
T481 | 68-80 | UBERON:0002342 | denotes | neural crest |
T482 | 68-85 | CL_EXT:neural_crest_cell | denotes | neural crest cell |
T483 | 81-85 | CL_GO_EXT:cell | denotes | cell |
T484 | 106-115 | GO_EXT:cell_communication_or_signaling_or_signal_transduction | denotes | signaling |
T485 | 120-124 | PR_EXT:000000047 | denotes | ALK5 |
T486 | 141-155 | UBERON:0004535 | denotes | cardiovascular |
T487 | 160-170 | UBERON:0006562 | denotes | pharyngeal |
T488 | 218-242 | UBERON:0004363 | denotes | pharyngeal arch arteries |
T489 | 253-263 | UBERON:0005432 | denotes | aortic sac |
T490 | 288-298 | UBERON:0006562 | denotes | pharyngeal |
T491 | 299-304 | UBERON:0000062 | denotes | organ |
T492 | 305-314 | GO_EXT:biological_movement_or_translocation_process | denotes | migration |
T493 | 330-348 | UBERON:0002061 | denotes | truncus arteriosus |
T494 | 356-360 | PR_EXT:000000047 | denotes | ALK5 |
T495 | 381-393 | UBERON:0002342 | denotes | neural crest |
T496 | 381-398 | CL_EXT:neural_crest_cell | denotes | neural crest cell |
T497 | 381-408 | GO:0001755 | denotes | neural crest cell migration |
T498 | 394-398 | CL_GO_EXT:cell | denotes | cell |
T499 | 490-499 | GO_EXT:biological_movement_or_translocation_process | denotes | migratory |
T500 | 500-520 | UBERON:0000095 | denotes | cardiac neural crest |
T501 | 508-526 | CL_EXT:neural_crest_cell | denotes | neural crest cells |
T502 | 521-526 | CL_GO_EXT:cell | denotes | cells |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T423 | 15-20 | PR:000000046 | denotes | TGF-β |
T424 | 37-41 | PR:000000047 | denotes | Alk5 |
T425 | 62-67 | NCBITaxon:10088 | denotes | mouse |
T426 | 68-80 | UBERON:0002342 | denotes | neural crest |
T427 | 120-124 | PR:000000047 | denotes | ALK5 |
T428 | 141-155 | UBERON:0004535 | denotes | cardiovascular |
T429 | 160-170 | UBERON:0006562 | denotes | pharyngeal |
T430 | 218-242 | UBERON:0004363 | denotes | pharyngeal arch arteries |
T431 | 253-263 | UBERON:0005432 | denotes | aortic sac |
T432 | 288-298 | UBERON:0006562 | denotes | pharyngeal |
T433 | 299-304 | UBERON:0000062 | denotes | organ |
T434 | 330-348 | UBERON:0002061 | denotes | truncus arteriosus |
T435 | 356-360 | PR:000000047 | denotes | ALK5 |
T436 | 381-393 | UBERON:0002342 | denotes | neural crest |
T437 | 381-408 | GO:0001755 | denotes | neural crest cell migration |
T438 | 500-520 | UBERON:0000095 | denotes | cardiac neural crest |