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PMC:1635039 / 5991-6775 JSONTXT

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Id Subject Object Predicate Lexical cue
T4642 0-2 TO denotes To
T4643 3-13 VB denotes inactivate
T4644 105-112 VBN denotes crossed
T4645 14-18 NN denotes Alk5
T4646 19-21 IN denotes in
T4647 22-29 JJ denotes cardiac
T4648 30-34 NNS denotes NCCs
T4649 34-36 , denotes ,
T4650 36-40 NNS denotes mice
T4651 41-51 JJ denotes homozygous
T4652 52-55 IN denotes for
T4653 56-59 DT denotes the
T4654 72-78 NN denotes allele
T4655 60-66 VBN denotes floxed
T4656 67-71 NN denotes Alk5
T4657 79-80 -LRB- denotes (
T4658 80-88 NN denotes Alk5Flox
T4659 89-93 NN denotes Flox
T4660 88-89 HYPH denotes /
T4661 93-94 -RRB- denotes )
T4662 95-96 -LRB- denotes [
T4663 96-98 CD denotes 21
T4664 98-99 -RRB- denotes ]
T4665 100-104 VBD denotes were
T4666 113-117 IN denotes with
T4667 118-128 JJ denotes transgenic
T4668 138-142 NNS denotes mice
T4669 129-133 NN denotes Wnt1
T4670 134-137 NN denotes Cre
T4671 133-134 HYPH denotes -
T4672 143-144 -LRB- denotes [
T4673 144-146 CD denotes 22
T4674 146-147 -RRB- denotes ]
T4675 147-149 , denotes ,
T4676 149-154 WDT denotes which
T4677 155-159 VBD denotes were
T4678 160-164 RB denotes also
T4679 165-177 JJ denotes heterozygous
T4680 178-181 IN denotes for
T4681 182-185 DT denotes the
T4682 200-206 NN denotes allele
T4683 186-190 NN denotes Alk5
T4684 191-199 NN denotes knockout
T4685 207-208 -LRB- denotes (
T4686 208-214 NN denotes Alk5KO
T4687 216-222 NN denotes allele
T4688 214-215 -RRB- denotes )
T4689 222-223 . denotes .
T4690 223-559 sentence denotes The resulting mice heterozygous for the Alk5Flox and Alk5KO alleles, which also carried the Wnt1-Cre transgene, had the Alk5 gene specifically inactivated in NCCs (herein termed Alk5/Wnt1-Cre), while the littermates with remaining allelic combinations were phenotypically normal and served as controls (Alk5Flox/+, Alk5KO/+; Wnt1-Cre).
T4691 224-227 DT denotes The
T4692 238-242 NNS denotes mice
T4693 228-237 VBG denotes resulting
T4694 336-339 VBD denotes had
T4695 243-255 JJ denotes heterozygous
T4696 256-259 IN denotes for
T4697 260-263 DT denotes the
T4698 284-291 NNS denotes alleles
T4699 264-272 NN denotes Alk5Flox
T4700 273-276 CC denotes and
T4701 277-283 NN denotes Alk5KO
T4702 291-293 , denotes ,
T4703 293-298 WDT denotes which
T4704 304-311 VBD denotes carried
T4705 299-303 RB denotes also
T4706 312-315 DT denotes the
T4707 325-334 NN denotes transgene
T4708 316-320 NN denotes Wnt1
T4709 321-324 NN denotes Cre
T4710 320-321 HYPH denotes -
T4711 334-336 , denotes ,
T4712 340-343 DT denotes the
T4713 349-353 NN denotes gene
T4714 344-348 NN denotes Alk5
T4715 354-366 RB denotes specifically
T4716 367-378 VBN denotes inactivated
T4717 379-381 IN denotes in
T4718 382-386 NNS denotes NCCs
T4719 387-388 -LRB- denotes (
T4720 388-394 RB denotes herein
T4721 395-401 VBN denotes termed
T4722 402-406 NN denotes Alk5
T4723 412-415 NN denotes Cre
T4724 406-407 HYPH denotes /
T4725 407-411 NN denotes Wnt1
T4726 411-412 HYPH denotes -
T4727 415-416 -RRB- denotes )
T4728 416-418 , denotes ,
T4729 418-423 IN denotes while
T4730 476-480 VBD denotes were
T4731 424-427 DT denotes the
T4732 428-439 NNS denotes littermates
T4733 440-444 IN denotes with
T4734 445-454 VBG denotes remaining
T4735 463-475 NNS denotes combinations
T4736 455-462 JJ denotes allelic
T4737 481-495 RB denotes phenotypically
T4738 496-502 JJ denotes normal
T4739 503-506 CC denotes and
T4740 507-513 VBD denotes served
T4741 514-516 IN denotes as
T4742 517-525 NNS denotes controls
T4743 526-527 -LRB- denotes (
T4744 554-557 NN denotes Cre
T4745 527-535 NN denotes Alk5Flox
T4746 535-536 HYPH denotes /
T4747 536-537 SYM denotes +
T4748 537-539 , denotes ,
T4749 539-545 NN denotes Alk5KO
T4750 545-546 HYPH denotes /
T4751 546-547 SYM denotes +
T4752 547-548 : denotes ;
T4753 549-553 NN denotes Wnt1
T4754 553-554 HYPH denotes -
T4755 557-558 -RRB- denotes )
T4756 558-559 . denotes .
T4757 559-687 sentence denotes When embryos were harvested during the last day of gestation, an expected number (25%) of Alk5/Wnt1-Cre mutants were recovered.
T4758 560-564 WRB denotes When
T4759 578-587 VBN denotes harvested
T4760 565-572 NNS denotes embryos
T4761 573-577 VBD denotes were
T4762 677-686 VBN denotes recovered
T4763 588-594 IN denotes during
T4764 595-598 DT denotes the
T4765 604-607 NN denotes day
T4766 599-603 JJ denotes last
T4767 608-610 IN denotes of
T4768 611-620 NN denotes gestation
T4769 620-622 , denotes ,
T4770 622-624 DT denotes an
T4771 634-640 NN denotes number
T4772 625-633 JJ denotes expected
T4773 641-642 -LRB- denotes (
T4774 642-644 CD denotes 25
T4775 644-645 NN denotes %
T4776 645-646 -RRB- denotes )
T4777 647-649 IN denotes of
T4778 650-654 NN denotes Alk5
T4779 660-663 NN denotes Cre
T4780 654-655 HYPH denotes /
T4781 655-659 NN denotes Wnt1
T4782 659-660 HYPH denotes -
T4783 664-671 NNS denotes mutants
T4784 672-676 VBD denotes were
T4785 686-687 . denotes .
T4786 687-784 sentence denotes However, all mutant offspring died either during the birth or during the first post-natal hours.
T4787 688-695 RB denotes However
T4788 718-722 VBD denotes died
T4789 695-697 , denotes ,
T4790 697-700 DT denotes all
T4791 708-717 NN denotes offspring
T4792 701-707 NN denotes mutant
T4793 723-729 CC denotes either
T4794 730-736 IN denotes during
T4795 737-740 DT denotes the
T4796 741-746 NN denotes birth
T4797 747-749 CC denotes or
T4798 750-756 IN denotes during
T4799 757-760 DT denotes the
T4800 778-783 NNS denotes hours
T4801 761-766 JJ denotes first
T4802 767-777 JJ denotes post-natal
T4803 783-784 . denotes .
R1107 T4642 T4643 aux To,inactivate
R1108 T4643 T4644 advcl inactivate,crossed
R1109 T4645 T4643 dobj Alk5,inactivate
R1110 T4646 T4643 prep in,inactivate
R1111 T4647 T4648 amod cardiac,NCCs
R1112 T4648 T4646 pobj NCCs,in
R1113 T4649 T4644 punct ", ",crossed
R1114 T4650 T4644 nsubjpass mice,crossed
R1115 T4651 T4650 amod homozygous,mice
R1116 T4652 T4651 prep for,homozygous
R1117 T4653 T4654 det the,allele
R1118 T4654 T4652 pobj allele,for
R1119 T4655 T4654 amod floxed,allele
R1120 T4656 T4654 compound Alk5,allele
R1121 T4657 T4654 punct (,allele
R1122 T4658 T4659 compound Alk5Flox,Flox
R1123 T4659 T4654 appos Flox,allele
R1124 T4660 T4659 punct /,Flox
R1125 T4661 T4650 punct ),mice
R1126 T4662 T4663 punct [,21
R1127 T4663 T4650 parataxis 21,mice
R1128 T4664 T4663 punct ],21
R1129 T4665 T4644 auxpass were,crossed
R1130 T4666 T4644 prep with,crossed
R1131 T4667 T4668 amod transgenic,mice
R1132 T4668 T4666 pobj mice,with
R1133 T4669 T4670 compound Wnt1,Cre
R1134 T4670 T4668 compound Cre,mice
R1135 T4671 T4670 punct -,Cre
R1136 T4672 T4673 punct [,22
R1137 T4673 T4668 parataxis 22,mice
R1138 T4674 T4673 punct ],22
R1139 T4675 T4668 punct ", ",mice
R1140 T4676 T4677 dep which,were
R1141 T4677 T4668 relcl were,mice
R1142 T4678 T4677 advmod also,were
R1143 T4679 T4677 acomp heterozygous,were
R1144 T4680 T4679 prep for,heterozygous
R1145 T4681 T4682 det the,allele
R1146 T4682 T4680 pobj allele,for
R1147 T4683 T4682 compound Alk5,allele
R1148 T4684 T4682 compound knockout,allele
R1149 T4685 T4682 punct (,allele
R1150 T4686 T4687 nmod Alk5KO,allele
R1151 T4687 T4682 appos allele,allele
R1152 T4688 T4687 punct ),allele
R1153 T4689 T4644 punct .,crossed
R1154 T4691 T4692 det The,mice
R1155 T4692 T4694 nsubj mice,had
R1156 T4693 T4692 amod resulting,mice
R1157 T4695 T4692 amod heterozygous,mice
R1158 T4696 T4695 prep for,heterozygous
R1159 T4697 T4698 det the,alleles
R1160 T4698 T4696 pobj alleles,for
R1161 T4699 T4698 nmod Alk5Flox,alleles
R1162 T4700 T4699 cc and,Alk5Flox
R1163 T4701 T4699 conj Alk5KO,Alk5Flox
R1164 T4702 T4698 punct ", ",alleles
R1165 T4703 T4704 dep which,carried
R1166 T4704 T4698 relcl carried,alleles
R1167 T4705 T4704 advmod also,carried
R1168 T4706 T4707 det the,transgene
R1169 T4707 T4704 dobj transgene,carried
R1170 T4708 T4709 compound Wnt1,Cre
R1171 T4709 T4707 compound Cre,transgene
R1172 T4710 T4709 punct -,Cre
R1173 T4711 T4694 punct ", ",had
R1174 T4712 T4713 det the,gene
R1175 T4713 T4694 dobj gene,had
R1176 T4714 T4713 compound Alk5,gene
R1177 T4715 T4716 advmod specifically,inactivated
R1178 T4716 T4713 acl inactivated,gene
R1179 T4717 T4716 prep in,inactivated
R1180 T4718 T4717 pobj NCCs,in
R1181 T4719 T4718 punct (,NCCs
R1182 T4720 T4721 advmod herein,termed
R1183 T4721 T4718 acl termed,NCCs
R1184 T4722 T4723 compound Alk5,Cre
R1185 T4723 T4721 oprd Cre,termed
R1186 T4724 T4723 punct /,Cre
R1187 T4725 T4723 compound Wnt1,Cre
R1188 T4726 T4723 punct -,Cre
R1189 T4727 T4694 punct ),had
R1190 T4728 T4694 punct ", ",had
R1191 T4729 T4730 mark while,were
R1192 T4730 T4694 advcl were,had
R1193 T4731 T4732 det the,littermates
R1194 T4732 T4730 nsubj littermates,were
R1195 T4733 T4732 prep with,littermates
R1196 T4734 T4735 amod remaining,combinations
R1197 T4735 T4733 pobj combinations,with
R1198 T4736 T4735 amod allelic,combinations
R1199 T4737 T4738 advmod phenotypically,normal
R1200 T4738 T4730 acomp normal,were
R1201 T4739 T4730 cc and,were
R1202 T4740 T4730 conj served,were
R1203 T4741 T4740 prep as,served
R1204 T4742 T4741 pobj controls,as
R1205 T4743 T4744 punct (,Cre
R1206 T4744 T4740 parataxis Cre,served
R1207 T4745 T4744 dep Alk5Flox,Cre
R1208 T4746 T4745 punct /,Alk5Flox
R1209 T4747 T4745 punct +,Alk5Flox
R1210 T4748 T4744 punct ", ",Cre
R1211 T4749 T4744 dep Alk5KO,Cre
R1212 T4750 T4749 punct /,Alk5KO
R1213 T4751 T4749 punct +,Alk5KO
R1214 T4752 T4744 punct ;,Cre
R1215 T4753 T4744 compound Wnt1,Cre
R1216 T4754 T4744 punct -,Cre
R1217 T4755 T4744 punct ),Cre
R1218 T4756 T4694 punct .,had
R1219 T4758 T4759 advmod When,harvested
R1220 T4759 T4762 advcl harvested,recovered
R1221 T4760 T4759 nsubjpass embryos,harvested
R1222 T4761 T4759 auxpass were,harvested
R1223 T4763 T4759 prep during,harvested
R1224 T4764 T4765 det the,day
R1225 T4765 T4763 pobj day,during
R1226 T4766 T4765 amod last,day
R1227 T4767 T4765 prep of,day
R1228 T4768 T4767 pobj gestation,of
R1229 T4769 T4762 punct ", ",recovered
R1230 T4770 T4771 det an,number
R1231 T4771 T4762 nsubjpass number,recovered
R1232 T4772 T4771 amod expected,number
R1233 T4773 T4771 punct (,number
R1234 T4774 T4775 nummod 25,%
R1235 T4775 T4771 appos %,number
R1236 T4776 T4771 punct ),number
R1237 T4777 T4771 prep of,number
R1238 T4778 T4779 compound Alk5,Cre
R1239 T4779 T4783 compound Cre,mutants
R1240 T4780 T4779 punct /,Cre
R1241 T4781 T4779 compound Wnt1,Cre
R1242 T4782 T4779 punct -,Cre
R1243 T4783 T4777 pobj mutants,of
R1244 T4784 T4762 auxpass were,recovered
R1245 T4785 T4762 punct .,recovered
R1246 T4787 T4788 advmod However,died
R1247 T4789 T4788 punct ", ",died
R1248 T4790 T4791 det all,offspring
R1249 T4791 T4788 nsubj offspring,died
R1250 T4792 T4791 compound mutant,offspring
R1251 T4793 T4794 preconj either,during
R1252 T4794 T4788 prep during,died
R1253 T4795 T4796 det the,birth
R1254 T4796 T4794 pobj birth,during
R1255 T4797 T4794 cc or,during
R1256 T4798 T4794 conj during,during
R1257 T4799 T4800 det the,hours
R1258 T4800 T4798 pobj hours,during
R1259 T4801 T4800 amod first,hours
R1260 T4802 T4800 amod post-natal,hours
R1261 T4803 T4788 punct .,died

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4564 549-553 PR_EXT:000017435 denotes Wnt1
T4565 565-572 UBERON:0000922 denotes embryos
T4566 611-620 GO:0007565 denotes gestation
T4567 650-654 PR_EXT:000000047 denotes Alk5
T4568 655-659 PR_EXT:000017435 denotes Wnt1
T4529 14-18 PR_EXT:000000047 denotes Alk5
T4530 22-29 UBERON:0000948 denotes cardiac
T4531 30-34 CL_EXT:neural_crest_cell denotes NCCs
T4532 36-40 NCBITaxon:10088 denotes mice
T4533 60-66 SO:0000359 denotes floxed
T4534 67-71 PR_EXT:000000047 denotes Alk5
T4535 72-78 SO_EXT:0001023 denotes allele
T4536 80-84 PR_EXT:000000047 denotes Alk5
T4537 84-88 SO:0000359 denotes Flox
T4538 89-93 SO:0000359 denotes Flox
T4539 118-128 SO_EXT:transgenic_entity denotes transgenic
T4540 129-133 PR_EXT:000017435 denotes Wnt1
T4541 138-142 NCBITaxon:10088 denotes mice
T4542 186-190 PR_EXT:000000047 denotes Alk5
T4543 200-206 SO_EXT:0001023 denotes allele
T4544 208-212 PR_EXT:000000047 denotes Alk5
T4545 216-222 SO_EXT:0001023 denotes allele
T4546 238-242 NCBITaxon:10088 denotes mice
T4547 264-268 PR_EXT:000000047 denotes Alk5
T4548 268-272 SO:0000359 denotes Flox
T4549 277-281 PR_EXT:000000047 denotes Alk5
T4550 284-291 SO_EXT:0001023 denotes alleles
T4551 316-320 PR_EXT:000017435 denotes Wnt1
T4552 325-334 SO_EXT:0000902 denotes transgene
T4553 344-348 PR_EXT:000000047 denotes Alk5
T4554 349-353 SO_EXT:0000704 denotes gene
T4555 382-386 CL_EXT:neural_crest_cell denotes NCCs
T4556 402-406 PR_EXT:000000047 denotes Alk5
T4557 407-411 PR_EXT:000017435 denotes Wnt1
T4558 455-462 SO_EXT:0001023 denotes allelic
T4559 527-531 PR_EXT:000000047 denotes Alk5
T4560 531-535 SO:0000359 denotes Flox
T4561 536-537 SO_EXT:normal_or_wild_type_or_present denotes +
T4562 539-543 PR_EXT:000000047 denotes Alk5
T4563 546-547 SO_EXT:normal_or_wild_type_or_present denotes +
T4569 664-671 SO_EXT:sequence_altered_entity denotes mutants
T4570 701-707 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T4571 718-722 GO:0016265 denotes died
T4572 741-746 GO:0007567 denotes birth
T4573 772-777 GO:0007567 denotes natal

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4457 238-242 NCBITaxon:10088 denotes mice
T4458 264-268 PR:000000047 denotes Alk5
T4459 268-272 SO:0000359 denotes Flox
T4460 277-281 PR:000000047 denotes Alk5
T4461 284-291 SO:0001023 denotes alleles
T4462 316-320 PR:000017435 denotes Wnt1
T4463 325-334 SO:0000902 denotes transgene
T4464 344-348 PR:000000047 denotes Alk5
T4465 349-353 SO:0000704 denotes gene
T4466 402-406 PR:000000047 denotes Alk5
T4467 407-411 PR:000017435 denotes Wnt1
T4468 455-462 SO:0001023 denotes allelic
T4469 527-531 PR:000000047 denotes Alk5
T4470 531-535 SO:0000359 denotes Flox
T4471 539-543 PR:000000047 denotes Alk5
T4472 549-553 PR:000017435 denotes Wnt1
T4473 565-572 UBERON:0000922 denotes embryos
T4474 611-620 GO:0007565 denotes gestation
T4475 650-654 PR:000000047 denotes Alk5
T4476 655-659 PR:000017435 denotes Wnt1
T4477 718-722 GO:0016265 denotes died
T4478 741-746 GO:0007567 denotes birth
T4479 772-777 GO:0007567 denotes natal
T4442 14-18 PR:000000047 denotes Alk5
T4443 22-29 UBERON:0000948 denotes cardiac
T4444 36-40 NCBITaxon:10088 denotes mice
T4445 60-66 SO:0000359 denotes floxed
T4446 67-71 PR:000000047 denotes Alk5
T4447 72-78 SO:0001023 denotes allele
T4448 80-84 PR:000000047 denotes Alk5
T4449 84-88 SO:0000359 denotes Flox
T4450 89-93 SO:0000359 denotes Flox
T4451 129-133 PR:000017435 denotes Wnt1
T4452 138-142 NCBITaxon:10088 denotes mice
T4453 186-190 PR:000000047 denotes Alk5
T4454 200-206 SO:0001023 denotes allele
T4455 208-212 PR:000000047 denotes Alk5
T4456 216-222 SO:0001023 denotes allele