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PMC:1635039 / 29941-30577 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T15539 11-13 IN denotes In
T15540 34-41 VBN denotes deleted
T15541 14-18 DT denotes this
T15542 19-24 NN denotes study
T15543 24-26 , denotes ,
T15544 26-28 PRP denotes we
T15545 29-33 VBP denotes have
T15546 42-45 DT denotes the
T15547 75-79 NN denotes gene
T15548 46-49 NN denotes TGF
T15549 50-51 NN denotes β
T15550 49-50 HYPH denotes -
T15551 52-56 NN denotes type
T15552 57-58 CD denotes I
T15553 59-67 NN denotes receptor
T15554 68-69 -LRB- denotes (
T15555 69-73 NN denotes Alk5
T15556 73-74 -RRB- denotes )
T15557 80-92 RB denotes specifically
T15558 93-95 IN denotes in
T15559 96-99 DT denotes the
T15560 129-136 NN denotes lineage
T15561 100-105 NN denotes mouse
T15562 106-112 JJ denotes neural
T15563 113-118 NN denotes crest
T15564 119-120 -LRB- denotes (
T15565 120-122 NN denotes NC
T15566 122-123 -RRB- denotes )
T15567 124-128 NN denotes cell
T15568 136-137 . denotes .
T15569 137-334 sentence denotes Our data suggest that ALK5 is required cell autonomously in the NC to mediate non-redundant signaling events that are essential for appropriate patterning of the pharyngeal organs and cardiac OFT.
T15570 138-141 PRP$ denotes Our
T15571 142-146 NNS denotes data
T15572 147-154 VBP denotes suggest
T15573 155-159 IN denotes that
T15574 168-176 VBN denotes required
T15575 160-164 NN denotes ALK5
T15576 165-167 VBZ denotes is
T15577 177-181 NN denotes cell
T15578 182-194 RB denotes autonomously
T15579 195-197 IN denotes in
T15580 198-201 DT denotes the
T15581 202-204 NN denotes NC
T15582 205-207 TO denotes to
T15583 208-215 VB denotes mediate
T15584 216-229 JJ denotes non-redundant
T15585 240-246 NNS denotes events
T15586 230-239 NN denotes signaling
T15587 247-251 WDT denotes that
T15588 252-255 VBP denotes are
T15589 256-265 JJ denotes essential
T15590 266-269 IN denotes for
T15591 270-281 JJ denotes appropriate
T15592 282-292 NN denotes patterning
T15593 293-295 IN denotes of
T15594 296-299 DT denotes the
T15595 311-317 NNS denotes organs
T15596 300-310 JJ denotes pharyngeal
T15597 318-321 CC denotes and
T15598 322-329 JJ denotes cardiac
T15599 330-333 NN denotes OFT
T15600 333-334 . denotes .
T15601 334-636 sentence denotes The cardiac and pharyngeal defects observed in the NC-specific Alk5 mutants differ significantly from those seen in corresponding mutants lacking the TGF-β type II receptor, suggesting that signaling mediated by ALK5 is not limited to the classical TGF-β ligands during cardiac/pharyngeal development.
T15602 335-338 DT denotes The
T15603 362-369 NNS denotes defects
T15604 339-346 JJ denotes cardiac
T15605 347-350 CC denotes and
T15606 351-361 JJ denotes pharyngeal
T15607 411-417 VBP denotes differ
T15608 370-378 VBN denotes observed
T15609 379-381 IN denotes in
T15610 382-385 DT denotes the
T15611 403-410 NNS denotes mutants
T15612 386-388 NN denotes NC
T15613 389-397 JJ denotes specific
T15614 388-389 HYPH denotes -
T15615 398-402 NN denotes Alk5
T15616 418-431 RB denotes significantly
T15617 432-436 IN denotes from
T15618 437-442 DT denotes those
T15619 443-447 VBN denotes seen
T15620 448-450 IN denotes in
T15621 451-464 VBG denotes corresponding
T15622 465-472 NNS denotes mutants
T15623 473-480 VBG denotes lacking
T15624 481-484 DT denotes the
T15625 499-507 NN denotes receptor
T15626 485-488 NN denotes TGF
T15627 489-490 NN denotes β
T15628 488-489 HYPH denotes -
T15629 491-495 NN denotes type
T15630 496-498 CD denotes II
T15631 507-509 , denotes ,
T15632 509-519 VBG denotes suggesting
T15633 520-524 IN denotes that
T15634 559-566 VBN denotes limited
T15635 525-534 NN denotes signaling
T15636 535-543 VBN denotes mediated
T15637 544-546 IN denotes by
T15638 547-551 NN denotes ALK5
T15639 552-554 VBZ denotes is
T15640 555-558 RB denotes not
T15641 567-569 IN denotes to
T15642 570-573 DT denotes the
T15643 590-597 NNS denotes ligands
T15644 574-583 JJ denotes classical
T15645 584-587 NN denotes TGF
T15646 588-589 NN denotes β
T15647 587-588 HYPH denotes -
T15648 598-604 IN denotes during
T15649 605-612 JJ denotes cardiac
T15650 613-623 JJ denotes pharyngeal
T15651 612-613 HYPH denotes /
T15652 624-635 NN denotes development
T15653 635-636 . denotes .
R4720 T15539 T15540 prep In,deleted
R4721 T15541 T15542 det this,study
R4722 T15542 T15539 pobj study,In
R4723 T15543 T15540 punct ", ",deleted
R4724 T15544 T15540 nsubj we,deleted
R4725 T15545 T15540 aux have,deleted
R4726 T15546 T15547 det the,gene
R4727 T15547 T15540 dobj gene,deleted
R4728 T15548 T15549 nmod TGF,β
R4729 T15549 T15547 nmod β,gene
R4730 T15550 T15549 punct -,β
R4731 T15551 T15547 nmod type,gene
R4732 T15552 T15551 nummod I,type
R4733 T15553 T15547 nmod receptor,gene
R4734 T15554 T15547 punct (,gene
R4735 T15555 T15547 nmod Alk5,gene
R4736 T15556 T15547 punct ),gene
R4737 T15557 T15540 advmod specifically,deleted
R4738 T15558 T15540 prep in,deleted
R4739 T15559 T15560 det the,lineage
R4740 T15560 T15558 pobj lineage,in
R4741 T15561 T15560 nmod mouse,lineage
R4742 T15562 T15563 amod neural,crest
R4743 T15563 T15560 nmod crest,lineage
R4744 T15564 T15563 punct (,crest
R4745 T15565 T15563 appos NC,crest
R4746 T15566 T15560 punct ),lineage
R4747 T15567 T15560 compound cell,lineage
R4748 T15568 T15540 punct .,deleted
R4749 T15570 T15571 poss Our,data
R4750 T15571 T15572 nsubj data,suggest
R4751 T15573 T15574 mark that,required
R4752 T15574 T15572 ccomp required,suggest
R4753 T15575 T15574 nsubjpass ALK5,required
R4754 T15576 T15574 auxpass is,required
R4755 T15577 T15578 npadvmod cell,autonomously
R4756 T15578 T15574 advmod autonomously,required
R4757 T15579 T15574 prep in,required
R4758 T15580 T15581 det the,NC
R4759 T15581 T15579 pobj NC,in
R4760 T15582 T15583 aux to,mediate
R4761 T15583 T15574 advcl mediate,required
R4762 T15584 T15585 amod non-redundant,events
R4763 T15585 T15583 dobj events,mediate
R4764 T15586 T15585 compound signaling,events
R4765 T15587 T15588 dep that,are
R4766 T15588 T15585 relcl are,events
R4767 T15589 T15588 acomp essential,are
R4768 T15590 T15589 prep for,essential
R4769 T15591 T15592 amod appropriate,patterning
R4770 T15592 T15590 pobj patterning,for
R4771 T15593 T15592 prep of,patterning
R4772 T15594 T15595 det the,organs
R4773 T15595 T15593 pobj organs,of
R4774 T15596 T15595 amod pharyngeal,organs
R4775 T15597 T15595 cc and,organs
R4776 T15598 T15599 amod cardiac,OFT
R4777 T15599 T15595 conj OFT,organs
R4778 T15600 T15572 punct .,suggest
R4779 T15602 T15603 det The,defects
R4780 T15603 T15607 nsubj defects,differ
R4781 T15604 T15603 amod cardiac,defects
R4782 T15605 T15604 cc and,cardiac
R4783 T15606 T15604 conj pharyngeal,cardiac
R4784 T15608 T15603 acl observed,defects
R4785 T15609 T15608 prep in,observed
R4786 T15610 T15611 det the,mutants
R4787 T15611 T15609 pobj mutants,in
R4788 T15612 T15613 npadvmod NC,specific
R4789 T15613 T15611 amod specific,mutants
R4790 T15614 T15613 punct -,specific
R4791 T15615 T15611 compound Alk5,mutants
R4792 T15616 T15607 advmod significantly,differ
R4793 T15617 T15607 prep from,differ
R4794 T15618 T15617 pobj those,from
R4795 T15619 T15618 acl seen,those
R4796 T15620 T15619 prep in,seen
R4797 T15621 T15622 amod corresponding,mutants
R4798 T15622 T15620 pobj mutants,in
R4799 T15623 T15622 acl lacking,mutants
R4800 T15624 T15625 det the,receptor
R4801 T15625 T15623 dobj receptor,lacking
R4802 T15626 T15627 nmod TGF,β
R4803 T15627 T15625 nmod β,receptor
R4804 T15628 T15627 punct -,β
R4805 T15629 T15625 nmod type,receptor
R4806 T15630 T15629 nummod II,type
R4807 T15631 T15607 punct ", ",differ
R4808 T15632 T15607 advcl suggesting,differ
R4809 T15633 T15634 mark that,limited
R4810 T15634 T15632 ccomp limited,suggesting
R4811 T15635 T15634 nsubjpass signaling,limited
R4812 T15636 T15635 acl mediated,signaling
R4813 T15637 T15636 agent by,mediated
R4814 T15638 T15637 pobj ALK5,by
R4815 T15639 T15634 auxpass is,limited
R4816 T15640 T15634 neg not,limited
R4817 T15641 T15634 prep to,limited
R4818 T15642 T15643 det the,ligands
R4819 T15643 T15641 pobj ligands,to
R4820 T15644 T15643 amod classical,ligands
R4821 T15645 T15646 compound TGF,β
R4822 T15646 T15643 compound β,ligands
R4823 T15647 T15646 punct -,β
R4824 T15648 T15634 prep during,limited
R4825 T15649 T15650 amod cardiac,pharyngeal
R4826 T15650 T15652 amod pharyngeal,development
R4827 T15651 T15650 punct /,pharyngeal
R4828 T15652 T15648 pobj development,during
R4829 T15653 T15607 punct .,differ

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15504 34-41 SO_EXT:sequence_deletion_process denotes deleted
T15505 46-67 GO_PR_EXT:transforming_growth_factor_beta_receptor_type_I denotes TGF-β type I receptor
T15506 69-73 PR_EXT:000000047 denotes Alk5
T15507 75-79 SO_EXT:0000704 denotes gene
T15508 100-105 NCBITaxon:10088 denotes mouse
T15509 106-118 UBERON:0002342 denotes neural crest
T15510 106-118 _FRAGMENT denotes neural crest
T15511 124-128 CL_EXT:neural_crest_cell denotes cell
T15512 120-122 UBERON:0002342 denotes NC
T15513 120-122 _FRAGMENT denotes NC
T15514 124-128 CL_GO_EXT:cell denotes cell
T15515 160-164 PR_EXT:000000047 denotes ALK5
T15516 177-181 CL_GO_EXT:cell denotes cell
T15517 202-204 UBERON:0002342 denotes NC
T15518 230-239 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T15519 282-292 GO_PATO_EXT:biological_patterning_process_or_quality denotes patterning
T15520 300-310 UBERON:0006562 denotes pharyngeal
T15521 311-317 UBERON:0000062 denotes organs
T15522 322-333 UBERON:0004145 denotes cardiac OFT
T15523 339-346 UBERON:0000948 denotes cardiac
T15524 351-361 UBERON:0006562 denotes pharyngeal
T15525 386-388 UBERON:0002342 denotes NC
T15526 398-402 PR_EXT:000000047 denotes Alk5
T15527 403-410 SO_EXT:sequence_altered_entity denotes mutants
T15528 465-472 SO_EXT:sequence_altered_entity denotes mutants
T15529 485-507 GO_PR_EXT:transforming_growth_factor_beta_receptor_type_II denotes TGF-β type II receptor
T15530 525-534 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T15531 547-551 PR_EXT:000000047 denotes ALK5
T15532 584-589 PR_EXT:000000046 denotes TGF-β
T15533 590-597 CHEBI_GO_EXT:ligand denotes ligands
T15534 605-612 UBERON:0000948 denotes cardiac
T15535 605-612 _FRAGMENT denotes cardiac
T15536 624-635 GO:0007507 denotes development
T15537 613-623 UBERON:0006562 denotes pharyngeal
T15538 613-635 GO:0060465 denotes pharyngeal development
R4717 T15511 T15510 _lexicallyChainedTo cell,neural crest
R4718 T15511 T15513 _lexicallyChainedTo cell,NC
R4719 T15536 T15535 _lexicallyChainedTo development,cardiac

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15481 46-51 PR:000000046 denotes TGF-β
T15482 69-73 PR:000000047 denotes Alk5
T15483 75-79 SO:0000704 denotes gene
T15484 100-105 NCBITaxon:10088 denotes mouse
T15485 106-118 UBERON:0002342 denotes neural crest
T15486 120-122 UBERON:0002342 denotes NC
T15487 160-164 PR:000000047 denotes ALK5
T15488 202-204 UBERON:0002342 denotes NC
T15489 300-310 UBERON:0006562 denotes pharyngeal
T15490 311-317 UBERON:0000062 denotes organs
T15491 322-333 UBERON:0004145 denotes cardiac OFT
T15492 339-346 UBERON:0000948 denotes cardiac
T15493 351-361 UBERON:0006562 denotes pharyngeal
T15494 386-388 UBERON:0002342 denotes NC
T15495 398-402 PR:000000047 denotes Alk5
T15496 485-490 PR:000000046 denotes TGF-β
T15497 547-551 PR:000000047 denotes ALK5
T15498 584-589 PR:000000046 denotes TGF-β
T15499 605-612 UBERON:0000948 denotes cardiac
T15500 605-612 _FRAGMENT denotes cardiac
T15501 624-635 GO:0007507 denotes development
T15502 613-623 UBERON:0006562 denotes pharyngeal
T15503 613-635 GO:0060465 denotes pharyngeal development
R4716 T15501 T15500 _lexicallyChainedTo development,cardiac