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PMC:1635039 / 25837-26656 JSONTXT

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Id Subject Object Predicate Lexical cue
T14462 0-2 PRP denotes We
T14463 16-23 VBD denotes studied
T14464 3-15 RB denotes specifically
T14465 24-33 NN denotes apoptosis
T14466 34-36 IN denotes at
T14467 37-40 DT denotes the
T14468 41-46 NN denotes level
T14469 47-49 IN denotes of
T14470 50-53 DT denotes the
T14471 61-64 NN denotes sac
T14472 54-60 JJ denotes aortic
T14473 64-66 , denotes ,
T14474 66-71 WRB denotes where
T14475 86-91 VBZ denotes forms
T14476 72-75 DT denotes the
T14477 79-85 NN denotes septum
T14478 76-78 NN denotes AP
T14479 78-79 HYPH denotes -
T14480 92-99 IN denotes between
T14481 100-103 DT denotes the
T14482 104-111 NNS denotes origins
T14483 112-114 IN denotes of
T14484 115-118 JJ denotes 4th
T14485 127-131 NNS denotes PAAs
T14486 119-122 CC denotes and
T14487 123-126 JJ denotes 6th
T14488 131-132 . denotes .
T14489 132-375 sentence denotes Already at E10.5, we could see intense apoptosis among the postmigratory NCCs in the mesenchyme surrounding the aortic sac at the site where the prospective AP septum forms, i.e., this cell death precedes the AP septal defect seen in mutants.
T14490 133-140 RB denotes Already
T14491 160-163 VB denotes see
T14492 141-143 IN denotes at
T14493 144-149 NN denotes E10.5
T14494 149-151 , denotes ,
T14495 151-153 PRP denotes we
T14496 154-159 MD denotes could
T14497 329-337 VBZ denotes precedes
T14498 164-171 JJ denotes intense
T14499 172-181 NN denotes apoptosis
T14500 182-187 IN denotes among
T14501 188-191 DT denotes the
T14502 206-210 NNS denotes NCCs
T14503 192-205 JJ denotes postmigratory
T14504 211-213 IN denotes in
T14505 214-217 DT denotes the
T14506 218-228 NN denotes mesenchyme
T14507 229-240 VBG denotes surrounding
T14508 241-244 DT denotes the
T14509 252-255 NN denotes sac
T14510 245-251 JJ denotes aortic
T14511 256-258 IN denotes at
T14512 259-262 DT denotes the
T14513 263-267 NN denotes site
T14514 268-273 WRB denotes where
T14515 300-305 VBZ denotes forms
T14516 274-277 DT denotes the
T14517 293-299 NN denotes septum
T14518 278-289 JJ denotes prospective
T14519 290-292 NN denotes AP
T14520 305-307 , denotes ,
T14521 307-311 FW denotes i.e.
T14522 311-313 , denotes ,
T14523 313-317 DT denotes this
T14524 323-328 NN denotes death
T14525 318-322 NN denotes cell
T14526 338-341 DT denotes the
T14527 352-358 NN denotes defect
T14528 342-344 NN denotes AP
T14529 345-351 JJ denotes septal
T14530 359-363 VBN denotes seen
T14531 364-366 IN denotes in
T14532 367-374 NNS denotes mutants
T14533 374-375 . denotes .
T14534 375-575 sentence denotes Although some NC-derived cells appeared to be differentiating to smooth muscle cells in the OFT (Fig. 6), we could never detect the AP septum forming in Alk5/Wnt1-Cre mutants between E10.5 and E11.5.
T14535 376-384 IN denotes Although
T14536 407-415 VBD denotes appeared
T14537 385-389 DT denotes some
T14538 401-406 NNS denotes cells
T14539 390-392 NN denotes NC
T14540 393-400 VBN denotes derived
T14541 392-393 HYPH denotes -
T14542 497-503 VB denotes detect
T14543 416-418 TO denotes to
T14544 422-437 VBG denotes differentiating
T14545 419-421 VB denotes be
T14546 438-440 IN denotes to
T14547 441-447 JJ denotes smooth
T14548 455-460 NNS denotes cells
T14549 448-454 NN denotes muscle
T14550 461-463 IN denotes in
T14551 464-467 DT denotes the
T14552 468-471 NN denotes OFT
T14553 472-473 -LRB- denotes (
T14554 473-477 NN denotes Fig.
T14555 478-479 CD denotes 6
T14556 479-480 -RRB- denotes )
T14557 480-482 , denotes ,
T14558 482-484 PRP denotes we
T14559 485-490 MD denotes could
T14560 491-496 RB denotes never
T14561 504-507 DT denotes the
T14562 511-517 NN denotes septum
T14563 508-510 NN denotes AP
T14564 518-525 VBG denotes forming
T14565 526-528 IN denotes in
T14566 529-533 NN denotes Alk5
T14567 539-542 NN denotes Cre
T14568 533-534 HYPH denotes /
T14569 534-538 NN denotes Wnt1
T14570 538-539 HYPH denotes -
T14571 543-550 NNS denotes mutants
T14572 551-558 IN denotes between
T14573 559-564 NN denotes E10.5
T14574 565-568 CC denotes and
T14575 569-574 NN denotes E11.5
T14576 574-575 . denotes .
T14577 575-683 sentence denotes These findings suggest that the pool of cells forming the AP septum is severely affected by the cell death.
T14578 576-581 DT denotes These
T14579 582-590 NNS denotes findings
T14580 591-598 VBP denotes suggest
T14581 599-603 IN denotes that
T14582 656-664 VBN denotes affected
T14583 604-607 DT denotes the
T14584 608-612 NN denotes pool
T14585 613-615 IN denotes of
T14586 616-621 NNS denotes cells
T14587 622-629 VBG denotes forming
T14588 630-633 DT denotes the
T14589 637-643 NN denotes septum
T14590 634-636 NN denotes AP
T14591 644-646 VBZ denotes is
T14592 647-655 RB denotes severely
T14593 665-667 IN denotes by
T14594 668-671 DT denotes the
T14595 677-682 NN denotes death
T14596 672-676 NN denotes cell
T14597 682-683 . denotes .
T14598 683-819 sentence denotes Moreover, it is likely that these cells forming the AP-septum die the before majority of them can differentiate to smooth muscle cells.
T14599 684-692 RB denotes Moreover
T14600 697-699 VBZ denotes is
T14601 692-694 , denotes ,
T14602 694-696 PRP denotes it
T14603 700-706 JJ denotes likely
T14604 707-711 IN denotes that
T14605 746-749 VBP denotes die
T14606 712-717 DT denotes these
T14607 718-723 NNS denotes cells
T14608 724-731 VBG denotes forming
T14609 732-735 DT denotes the
T14610 739-745 NN denotes septum
T14611 736-738 NN denotes AP
T14612 738-739 HYPH denotes -
T14613 750-753 DT denotes the
T14614 754-760 IN denotes before
T14615 782-795 VB denotes differentiate
T14616 761-769 NN denotes majority
T14617 770-772 IN denotes of
T14618 773-777 PRP denotes them
T14619 778-781 MD denotes can
T14620 796-798 IN denotes to
T14621 799-805 JJ denotes smooth
T14622 813-818 NNS denotes cells
T14623 806-812 NN denotes muscle
T14624 818-819 . denotes .
R3945 T14462 T14463 nsubj We,studied
R3947 T14464 T14463 advmod specifically,studied
R3948 T14465 T14463 dobj apoptosis,studied
R3951 T14466 T14465 prep at,apoptosis
R3952 T14467 T14468 det the,level
R3954 T14468 T14466 pobj level,at
R3955 T14469 T14468 prep of,level
R3956 T14470 T14471 det the,sac
R3958 T14471 T14469 pobj sac,of
R3959 T14472 T14471 amod aortic,sac
R3960 T14473 T14471 punct ", ",sac
R3962 T14474 T14475 advmod where,forms
R3964 T14475 T14471 relcl forms,sac
R3965 T14476 T14477 det the,septum
R3966 T14477 T14475 nsubj septum,forms
R3967 T14478 T14477 compound AP,septum
R3969 T14479 T14477 punct -,septum
R3970 T14480 T14475 prep between,forms
R3971 T14481 T14482 det the,origins
R3972 T14572 T14564 prep between,forming
R3973 T14482 T14480 pobj origins,between
R3974 T14483 T14482 prep of,origins
R3975 T14484 T14485 amod 4th,PAAs
R3976 T14573 T14572 pobj E10.5,between
R3977 T14485 T14483 pobj PAAs,of
R3978 T14486 T14484 cc and,4th
R3979 T14487 T14484 conj 6th,4th
R3980 T14574 T14573 cc and,E10.5
R3981 T14488 T14463 punct .,studied
R3982 T14490 T14491 advmod Already,see
R3983 T14575 T14573 conj E11.5,E10.5
R3984 T14491 T14497 ccomp see,precedes
R3985 T14492 T14491 prep at,see
R3986 T14576 T14542 punct .,detect
R3987 T14493 T14492 pobj E10.5,at
R3988 T14494 T14491 punct ", ",see
R3989 T14495 T14491 nsubj we,see
R3990 T14578 T14579 det These,findings
R3991 T14496 T14491 aux could,see
R3992 T14498 T14499 amod intense,apoptosis
R3993 T14579 T14580 nsubj findings,suggest
R3994 T14499 T14491 dobj apoptosis,see
R3995 T14500 T14499 prep among,apoptosis
R3996 T14501 T14502 det the,NCCs
R3997 T14581 T14582 mark that,affected
R3998 T14502 T14500 pobj NCCs,among
R3999 T14503 T14502 amod postmigratory,NCCs
R4000 T14504 T14491 prep in,see
R4001 T14505 T14506 det the,mesenchyme
R4002 T14506 T14504 pobj mesenchyme,in
R4003 T14507 T14506 acl surrounding,mesenchyme
R4004 T14582 T14580 ccomp affected,suggest
R4005 T14508 T14509 det the,sac
R4006 T14509 T14507 dobj sac,surrounding
R4007 T14510 T14509 amod aortic,sac
R4008 T14511 T14491 prep at,see
R4009 T14583 T14584 det the,pool
R4010 T14512 T14513 det the,site
R4011 T14513 T14511 pobj site,at
R4012 T14514 T14515 advmod where,forms
R4013 T14584 T14582 nsubjpass pool,affected
R4014 T14515 T14513 relcl forms,site
R4015 T14516 T14517 det the,septum
R4016 T14517 T14515 nsubj septum,forms
R4017 T14585 T14584 prep of,pool
R4018 T14518 T14517 amod prospective,septum
R4019 T14519 T14517 compound AP,septum
R4020 T14520 T14497 punct ", ",precedes
R4021 T14586 T14585 pobj cells,of
R4022 T14521 T14497 advmod i.e.,precedes
R4023 T14522 T14497 punct ", ",precedes
R4024 T14523 T14524 det this,death
R4025 T14587 T14584 acl forming,pool
R4026 T14524 T14497 nsubj death,precedes
R4027 T14525 T14524 compound cell,death
R4028 T14526 T14527 det the,defect
R4029 T14588 T14589 det the,septum
R4030 T14527 T14497 dobj defect,precedes
R4031 T14528 T14527 nmod AP,defect
R4032 T14529 T14527 amod septal,defect
R4033 T14589 T14587 dobj septum,forming
R4034 T14530 T14527 acl seen,defect
R4035 T14531 T14530 prep in,seen
R4036 T14590 T14589 compound AP,septum
R4037 T14532 T14531 pobj mutants,in
R4038 T14533 T14497 punct .,precedes
R4039 T14591 T14582 auxpass is,affected
R4040 T14535 T14536 mark Although,appeared
R4041 T14536 T14542 advcl appeared,detect
R4042 T14592 T14582 advmod severely,affected
R4043 T14537 T14538 det some,cells
R4044 T14538 T14536 nsubj cells,appeared
R4045 T14539 T14540 npadvmod NC,derived
R4046 T14593 T14582 agent by,affected
R4047 T14540 T14538 amod derived,cells
R4048 T14541 T14540 punct -,derived
R4049 T14594 T14595 det the,death
R4050 T14543 T14544 aux to,differentiating
R4051 T14544 T14536 xcomp differentiating,appeared
R4052 T14545 T14544 aux be,differentiating
R4053 T14546 T14544 prep to,differentiating
R4054 T14547 T14548 amod smooth,cells
R4055 T14595 T14593 pobj death,by
R4056 T14548 T14546 pobj cells,to
R4057 T14549 T14548 compound muscle,cells
R4058 T14550 T14544 prep in,differentiating
R4059 T14596 T14595 compound cell,death
R4060 T14551 T14552 det the,OFT
R4061 T14552 T14550 pobj OFT,in
R4062 T14553 T14554 punct (,Fig.
R4063 T14597 T14580 punct .,suggest
R4064 T14554 T14544 parataxis Fig.,differentiating
R4065 T14555 T14554 nummod 6,Fig.
R4066 T14556 T14554 punct ),Fig.
R4067 T14599 T14600 advmod Moreover,is
R4068 T14557 T14542 punct ", ",detect
R4069 T14558 T14542 nsubj we,detect
R4070 T14559 T14542 aux could,detect
R4071 T14560 T14542 neg never,detect
R4072 T14601 T14600 punct ", ",is
R4073 T14561 T14562 det the,septum
R4074 T14562 T14564 nsubj septum,forming
R4075 T14563 T14562 compound AP,septum
R4076 T14564 T14542 ccomp forming,detect
R4077 T14602 T14600 nsubj it,is
R4078 T14565 T14564 prep in,forming
R4079 T14566 T14567 compound Alk5,Cre
R4080 T14567 T14571 compound Cre,mutants
R4081 T14603 T14600 acomp likely,is
R4082 T14568 T14567 punct /,Cre
R4083 T14569 T14567 compound Wnt1,Cre
R4084 T14570 T14567 punct -,Cre
R4085 T14604 T14605 mark that,die
R4086 T14571 T14565 pobj mutants,in
R4087 T14605 T14600 ccomp die,is
R4088 T14606 T14607 det these,cells
R4089 T14607 T14605 nsubj cells,die
R4090 T14608 T14607 acl forming,cells
R4092 T14609 T14610 det the,septum
R4095 T14610 T14608 dobj septum,forming
R4098 T14611 T14610 compound AP,septum
R4102 T14612 T14610 punct -,septum
R4108 T14613 T14605 dep the,die
R4112 T14614 T14615 mark before,differentiate
R4114 T14615 T14605 advcl differentiate,die
R4118 T14616 T14615 nsubj majority,differentiate
R4120 T14617 T14616 prep of,majority
R4124 T14618 T14617 pobj them,of
R4126 T14619 T14615 aux can,differentiate
R4130 T14620 T14615 prep to,differentiate
R4134 T14621 T14622 amod smooth,cells
R4137 T14622 T14620 pobj cells,to
R4141 T14623 T14622 compound muscle,cells
R4144 T14624 T14600 punct .,is

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T13776 24-33 GO:0006915 denotes apoptosis
T13777 54-64 UBERON:0005432 denotes aortic sac
T13778 76-85 UBERON:0006207 denotes AP-septum
T13779 115-118 _FRAGMENT denotes 4th
T13780 127-131 UBERON:0003121 denotes PAAs
T13781 123-131 UBERON:0003123 denotes 6th PAAs
T13782 172-181 GO:0006915 denotes apoptosis
T13783 196-205 GO_EXT:biological_movement_or_translocation_process denotes migratory
T13784 206-210 CL_EXT:neural_crest_cell denotes NCCs
T13785 218-228 UBERON:0003104 denotes mesenchyme
T13786 245-255 UBERON:0005432 denotes aortic sac
T13787 290-299 UBERON:0006207 denotes AP septum
T13788 318-322 CL_GO_EXT:cell denotes cell
T13789 318-328 GO:0008219 denotes cell death
T13790 342-351 UBERON:0006207 denotes AP septal
T13791 367-374 SO_EXT:sequence_altered_entity denotes mutants
T13792 390-392 UBERON:0002342 denotes NC
T13793 401-406 CL_GO_EXT:cell denotes cells
T13794 422-437 GO_RO_EXT:developmental_differentiation_process denotes differentiating
T13795 441-454 UBERON:0001135 denotes smooth muscle
T13796 441-460 CL:0000192 denotes smooth muscle cells
T13797 455-460 CL_GO_EXT:cell denotes cells
T13798 468-471 UBERON:0004145 denotes OFT
T13799 508-517 UBERON:0006207 denotes AP septum
T13800 529-533 PR_EXT:000000047 denotes Alk5
T13801 534-538 PR_EXT:000017435 denotes Wnt1
T13802 543-550 SO_EXT:sequence_altered_entity denotes mutants
T13803 616-621 CL_GO_EXT:cell denotes cells
T13804 634-643 UBERON:0006207 denotes AP septum
T13805 672-676 CL_GO_EXT:cell denotes cell
T13806 672-682 GO:0008219 denotes cell death
T13807 718-723 CL_GO_EXT:cell denotes cells
T13808 736-745 UBERON:0006207 denotes AP-septum
T13809 746-749 GO:0016265 denotes die
T13810 782-795 GO_RO_EXT:developmental_differentiation_process denotes differentiate
T13811 799-812 UBERON:0001135 denotes smooth muscle
T13812 799-818 CL:0000192 denotes smooth muscle cells
T13813 813-818 CL_GO_EXT:cell denotes cells
R3447 T13780 T13779 _lexicallyChainedTo PAAs,4th

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T13560 24-33 GO:0006915 denotes apoptosis
T13561 54-64 UBERON:0005432 denotes aortic sac
T13562 76-85 UBERON:0006207 denotes AP-septum
T13563 115-118 _FRAGMENT denotes 4th
T13564 127-131 UBERON:0003121 denotes PAAs
T13565 123-131 UBERON:0003123 denotes 6th PAAs
T13566 172-181 GO:0006915 denotes apoptosis
T13567 218-228 UBERON:0003104 denotes mesenchyme
T13568 245-255 UBERON:0005432 denotes aortic sac
T13569 290-299 UBERON:0006207 denotes AP septum
T13570 318-328 GO:0008219 denotes cell death
T13571 342-351 UBERON:0006207 denotes AP septal
T13572 390-392 UBERON:0002342 denotes NC
T13573 441-454 UBERON:0001135 denotes smooth muscle
T13574 441-460 CL:0000192 denotes smooth muscle cells
T13575 468-471 UBERON:0004145 denotes OFT
T13576 508-517 UBERON:0006207 denotes AP septum
T13577 529-533 PR:000000047 denotes Alk5
T13578 534-538 PR:000017435 denotes Wnt1
T13579 634-643 UBERON:0006207 denotes AP septum
T13580 672-682 GO:0008219 denotes cell death
T13581 736-745 UBERON:0006207 denotes AP-septum
T13582 746-749 GO:0016265 denotes die
T13583 799-812 UBERON:0001135 denotes smooth muscle
T13584 799-818 CL:0000192 denotes smooth muscle cells
R3437 T13564 T13563 _lexicallyChainedTo PAAs,4th