PMC:1635039 / 24681-24927 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T14226","span":{"begin":0,"end":246},"obj":"sentence"},{"id":"T14227","span":{"begin":1,"end":6},"obj":"DT"},{"id":"T14228","span":{"begin":16,"end":27},"obj":"NNS"},{"id":"T14229","span":{"begin":7,"end":15},"obj":"VBN"},{"id":"T14230","span":{"begin":28,"end":31},"obj":"VBP"},{"id":"T14231","span":{"begin":32,"end":38},"obj":"RB"},{"id":"T14232","span":{"begin":39,"end":42},"obj":"IN"},{"id":"T14233","span":{"begin":43,"end":45},"obj":"IN"},{"id":"T14234","span":{"begin":46,"end":57},"obj":"JJ"},{"id":"T14235","span":{"begin":58,"end":67},"obj":"NN"},{"id":"T14236","span":{"begin":68,"end":70},"obj":"IN"},{"id":"T14237","span":{"begin":71,"end":75},"obj":"NN"},{"id":"T14238","span":{"begin":76,"end":85},"obj":"JJ"},{"id":"T14239","span":{"begin":75,"end":76},"obj":"HYPH"},{"id":"T14240","span":{"begin":114,"end":119},"obj":"NNS"},{"id":"T14241","span":{"begin":86,"end":100},"obj":"JJ"},{"id":"T14242","span":{"begin":101,"end":107},"obj":"JJ"},{"id":"T14243","span":{"begin":108,"end":113},"obj":"NN"},{"id":"T14244","span":{"begin":119,"end":121},"obj":","},{"id":"T14245","span":{"begin":121,"end":126},"obj":"WDT"},{"id":"T14246","span":{"begin":127,"end":129},"obj":"VBZ"},{"id":"T14247","span":{"begin":130,"end":137},"obj":"RB"},{"id":"T14248","span":{"begin":138,"end":148},"obj":"JJ"},{"id":"T14249","span":{"begin":149,"end":151},"obj":"IN"},{"id":"T14250","span":{"begin":152,"end":157},"obj":"NN"},{"id":"T14251","span":{"begin":157,"end":159},"obj":","},{"id":"T14252","span":{"begin":159,"end":166},"obj":"IN"},{"id":"T14253","span":{"begin":207,"end":215},"obj":"VBN"},{"id":"T14254","span":{"begin":167,"end":174},"obj":"JJ"},{"id":"T14256","span":{"begin":175,"end":182},"obj":"JJ"},{"id":"T14257","span":{"begin":183,"end":187},"obj":"NN"},{"id":"T14258","span":{"begin":194,"end":197},"obj":"VBZ"},{"id":"T14259","span":{"begin":198,"end":201},"obj":"RB"},{"id":"T14260","span":{"begin":202,"end":206},"obj":"VBN"},{"id":"T14261","span":{"begin":216,"end":218},"obj":"IN"},{"id":"T14262","span":{"begin":219,"end":225},"obj":"NN"},{"id":"T14263","span":{"begin":231,"end":234},"obj":"NN"},{"id":"T14264","span":{"begin":225,"end":226},"obj":"HYPH"},{"id":"T14265","span":{"begin":226,"end":230},"obj":"NN"},{"id":"T14266","span":{"begin":230,"end":231},"obj":"HYPH"},{"id":"T14267","span":{"begin":235,"end":242},"obj":"NNS"},{"id":"T14268","span":{"begin":242,"end":243},"obj":"-LRB-"},{"id":"T14269","span":{"begin":243,"end":244},"obj":"CD"},{"id":"T14270","span":{"begin":244,"end":245},"obj":"-RRB-"},{"id":"T14271","span":{"begin":245,"end":246},"obj":"."},{"id":"T14255","span":{"begin":188,"end":193},"obj":"NN"}],"relations":[{"id":"R3728","pred":"det","subj":"T14227","obj":"T14228"},{"id":"R3729","pred":"nsubj","subj":"T14228","obj":"T14230"},{"id":"R3730","pred":"amod","subj":"T14229","obj":"T14228"},{"id":"R3731","pred":"advmod","subj":"T14231","obj":"T14232"},{"id":"R3732","pred":"prep","subj":"T14232","obj":"T14230"},{"id":"R3733","pred":"pcomp","subj":"T14233","obj":"T14232"},{"id":"R3734","pred":"amod","subj":"T14234","obj":"T14235"},{"id":"R3735","pred":"pobj","subj":"T14235","obj":"T14232"},{"id":"R3736","pred":"prep","subj":"T14236","obj":"T14235"},{"id":"R3737","pred":"npadvmod","subj":"T14237","obj":"T14238"},{"id":"R3738","pred":"amod","subj":"T14238","obj":"T14240"},{"id":"R3739","pred":"punct","subj":"T14239","obj":"T14238"},{"id":"R3740","pred":"pobj","subj":"T14240","obj":"T14236"},{"id":"R3741","pred":"amod","subj":"T14241","obj":"T14240"},{"id":"R3742","pred":"amod","subj":"T14242","obj":"T14243"},{"id":"R3743","pred":"compound","subj":"T14243","obj":"T14240"},{"id":"R3744","pred":"punct","subj":"T14244","obj":"T14235"},{"id":"R3745","pred":"dep","subj":"T14245","obj":"T14246"},{"id":"R3746","pred":"relcl","subj":"T14246","obj":"T14235"},{"id":"R3747","pred":"advmod","subj":"T14247","obj":"T14248"},{"id":"R3748","pred":"acomp","subj":"T14248","obj":"T14246"},{"id":"R3749","pred":"prep","subj":"T14249","obj":"T14246"},{"id":"R3750","pred":"pobj","subj":"T14250","obj":"T14249"},{"id":"R3751","pred":"punct","subj":"T14251","obj":"T14246"},{"id":"R3752","pred":"mark","subj":"T14252","obj":"T14253"},{"id":"R3753","pred":"advcl","subj":"T14253","obj":"T14246"},{"id":"R3754","pred":"amod","subj":"T14254","obj":"T14255"},{"id":"R3755","pred":"nsubjpass","subj":"T14255","obj":"T14253"},{"id":"R3756","pred":"amod","subj":"T14256","obj":"T14255"},{"id":"R3757","pred":"compound","subj":"T14257","obj":"T14255"},{"id":"R3758","pred":"aux","subj":"T14258","obj":"T14253"},{"id":"R3759","pred":"neg","subj":"T14259","obj":"T14253"},{"id":"R3760","pred":"auxpass","subj":"T14260","obj":"T14253"},{"id":"R3761","pred":"prep","subj":"T14261","obj":"T14253"},{"id":"R3762","pred":"compound","subj":"T14262","obj":"T14263"},{"id":"R3763","pred":"compound","subj":"T14263","obj":"T14267"},{"id":"R3764","pred":"punct","subj":"T14264","obj":"T14263"},{"id":"R3765","pred":"compound","subj":"T14265","obj":"T14263"},{"id":"R3766","pred":"punct","subj":"T14266","obj":"T14263"},{"id":"R3767","pred":"pobj","subj":"T14267","obj":"T14261"},{"id":"R3768","pred":"punct","subj":"T14268","obj":"T14269"},{"id":"R3769","pred":"parataxis","subj":"T14269","obj":"T14230"},{"id":"R3770","pred":"punct","subj":"T14270","obj":"T14269"},{"id":"R3771","pred":"punct","subj":"T14271","obj":"T14230"}],"text":" These observed differences are likely due to substantial apoptosis of Alk5-deficient post-migratory neural crest cells, which is clearly detectable at E10.5, whereas similar intense cell death has not been reported in Tgfbr2/Wnt1-Cre mutants[9]."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T13719","span":{"begin":58,"end":70},"obj":"_FRAGMENT"},{"id":"T13720","span":{"begin":114,"end":119},"obj":"GO:0006915"},{"id":"T13721","span":{"begin":71,"end":75},"obj":"PR_EXT:000000047"},{"id":"T13722","span":{"begin":91,"end":100},"obj":"GO_EXT:biological_movement_or_translocation_process"},{"id":"T13723","span":{"begin":101,"end":113},"obj":"UBERON:0002342"},{"id":"T13724","span":{"begin":101,"end":119},"obj":"CL_EXT:neural_crest_cell"},{"id":"T13725","span":{"begin":114,"end":119},"obj":"CL_GO_EXT:cell"},{"id":"T13726","span":{"begin":183,"end":187},"obj":"CL_GO_EXT:cell"},{"id":"T13727","span":{"begin":183,"end":193},"obj":"GO:0008219"},{"id":"T13728","span":{"begin":219,"end":225},"obj":"GO_PR_EXT:transforming_growth_factor_beta_receptor_type_II"},{"id":"T13729","span":{"begin":226,"end":230},"obj":"PR_EXT:000017435"},{"id":"T13730","span":{"begin":235,"end":242},"obj":"SO_EXT:sequence_altered_entity"}],"relations":[{"id":"R3440","pred":"_lexicallyChainedTo","subj":"T13720","obj":"T13719"}],"text":" These observed differences are likely due to substantial apoptosis of Alk5-deficient post-migratory neural crest cells, which is clearly detectable at E10.5, whereas similar intense cell death has not been reported in Tgfbr2/Wnt1-Cre mutants[9]."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T13522","span":{"begin":58,"end":70},"obj":"_FRAGMENT"},{"id":"T13523","span":{"begin":114,"end":119},"obj":"GO:0006915"},{"id":"T13524","span":{"begin":71,"end":75},"obj":"PR:000000047"},{"id":"T13525","span":{"begin":101,"end":113},"obj":"UBERON:0002342"},{"id":"T13526","span":{"begin":183,"end":193},"obj":"GO:0008219"},{"id":"T13527","span":{"begin":226,"end":230},"obj":"PR:000017435"}],"relations":[{"id":"R3431","pred":"_lexicallyChainedTo","subj":"T13523","obj":"T13522"}],"text":" These observed differences are likely due to substantial apoptosis of Alk5-deficient post-migratory neural crest cells, which is clearly detectable at E10.5, whereas similar intense cell death has not been reported in Tgfbr2/Wnt1-Cre mutants[9]."}