PMC:1630425 / 14620-15653 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1630425","sourcedb":"PMC","sourceid":"1630425","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1630425","text":"Universal Sequence Mapping is an iterative procedure that populates a unitary hypercube bijectively: each sequence corresponds to a position in the map, and each map position corresponds to a unique sequence. For nucleotide sequences the hypercube has log2(4) = 2 dimensions, that is, it is a unit square. For that case, the original USM procedure in each direction is exactly equal to CGR. The same exercise for a sequence of aminoacids would produce a hypercube with 5 dimensions [14], which is the upper integer of log2(20). The edges of the hypercube correspond to the units of the alphabet that compose the sequence and the position is found by moving half the distance between the previous position and the edge corresponding to the unit at the position in the sequence being considered. This procedure, which was formally detailed in a previous report [3], is illustrated in Figure 1 for the sequence ACTGCC. The full USM procedure implements two such mappings, one in the forward and the other in the reverse directions [14].","tracks":[{"project":"2_test","denotations":[{"id":"17049089-11895567-1690145","span":{"begin":483,"end":485},"obj":"11895567"},{"id":"17049089-11331237-1690146","span":{"begin":860,"end":861},"obj":"11331237"},{"id":"17049089-11895567-1690147","span":{"begin":1029,"end":1031},"obj":"11895567"}],"attributes":[{"subj":"17049089-11895567-1690145","pred":"source","obj":"2_test"},{"subj":"17049089-11331237-1690146","pred":"source","obj":"2_test"},{"subj":"17049089-11895567-1690147","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93c4ec","default":true}]}]}}