PMC:1626108 / 43760-44582
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8488 | 0-10 | NN | denotes | Hexokinase |
T8489 | 13-21 | NN | denotes | activity |
T8490 | 11-12 | CD | denotes | I |
T8491 | 26-36 | VBN | denotes | determined |
T8492 | 22-25 | VBD | denotes | was |
T8493 | 37-59 | RB | denotes | spectrophotometrically |
T8494 | 60-62 | IN | denotes | at |
T8495 | 63-65 | CD | denotes | 25 |
T8496 | 66-68 | NN | denotes | °C |
T8497 | 69-71 | IN | denotes | by |
T8498 | 72-75 | DT | denotes | the |
T8499 | 76-82 | NN | denotes | method |
T8500 | 83-85 | IN | denotes | of |
T8501 | 86-94 | VBG | denotes | coupling |
T8502 | 95-98 | DT | denotes | the |
T8503 | 119-129 | NN | denotes | production |
T8504 | 99-106 | NN | denotes | glucose |
T8505 | 109-118 | NN | denotes | phosphate |
T8506 | 106-107 | HYPH | denotes | - |
T8507 | 107-108 | CD | denotes | 6 |
T8508 | 108-109 | HYPH | denotes | - |
T8509 | 130-133 | IN | denotes | via |
T8510 | 134-141 | NN | denotes | glucose |
T8511 | 144-153 | NN | denotes | phosphate |
T8512 | 141-142 | HYPH | denotes | - |
T8513 | 142-143 | CD | denotes | 6 |
T8514 | 143-144 | HYPH | denotes | - |
T8515 | 154-167 | NN | denotes | dehydrogenase |
T8516 | 168-172 | IN | denotes | with |
T8517 | 173-176 | DT | denotes | the |
T8518 | 177-183 | NN | denotes | change |
T8519 | 184-186 | IN | denotes | in |
T8520 | 187-190 | DT | denotes | the |
T8521 | 191-201 | NN | denotes | absorbance |
T8522 | 202-204 | IN | denotes | of |
T8523 | 205-210 | NN | denotes | NADPH |
T8524 | 211-213 | IN | denotes | at |
T8525 | 214-217 | CD | denotes | 340 |
T8526 | 218-220 | NN | denotes | nm |
T8527 | 221-224 | CC | denotes | and |
T8528 | 225-227 | IN | denotes | as |
T8529 | 228-237 | VBN | denotes | described |
T8530 | 238-240 | IN | denotes | by |
T8531 | 241-242 | -LRB- | denotes | [ |
T8532 | 242-244 | CD | denotes | 66 |
T8533 | 244-245 | -RRB- | denotes | ] |
T8534 | 245-246 | . | denotes | . |
T8535 | 246-532 | sentence | denotes | The reaction was started by the addition of purified brain hexokinase I (0.24 μg) (gift from J. Wilson) to 1.0 ml of reaction mixture containing 0.05 M Tris-HCl (pH 8.5), 7.4 mM MgCl2, 6.6 mM ATP, 0.65 mM NADP, 11.1 mM monothioglycerol, and 1 unit of glucose 6-phosphate dehydrogenase. |
T8536 | 247-250 | DT | denotes | The |
T8537 | 251-259 | NN | denotes | reaction |
T8538 | 264-271 | VBN | denotes | started |
T8539 | 260-263 | VBD | denotes | was |
T8540 | 272-274 | IN | denotes | by |
T8541 | 275-278 | DT | denotes | the |
T8542 | 279-287 | NN | denotes | addition |
T8543 | 288-290 | IN | denotes | of |
T8544 | 291-299 | VBN | denotes | purified |
T8545 | 306-316 | NN | denotes | hexokinase |
T8546 | 300-305 | NN | denotes | brain |
T8547 | 317-318 | CD | denotes | I |
T8548 | 319-320 | -LRB- | denotes | ( |
T8549 | 325-327 | NNS | denotes | μg |
T8550 | 320-324 | CD | denotes | 0.24 |
T8551 | 327-328 | -RRB- | denotes | ) |
T8552 | 329-330 | -LRB- | denotes | ( |
T8553 | 330-334 | NN | denotes | gift |
T8554 | 335-339 | IN | denotes | from |
T8555 | 340-342 | NNP | denotes | J. |
T8556 | 343-349 | NNP | denotes | Wilson |
T8557 | 349-350 | -RRB- | denotes | ) |
T8558 | 351-353 | IN | denotes | to |
T8559 | 354-357 | CD | denotes | 1.0 |
T8560 | 358-360 | NN | denotes | ml |
T8561 | 361-363 | IN | denotes | of |
T8562 | 364-372 | NN | denotes | reaction |
T8563 | 373-380 | NN | denotes | mixture |
T8564 | 381-391 | VBG | denotes | containing |
T8565 | 392-396 | CD | denotes | 0.05 |
T8566 | 397-398 | NNS | denotes | M |
T8567 | 404-407 | NN | denotes | HCl |
T8568 | 399-403 | NN | denotes | Tris |
T8569 | 403-404 | HYPH | denotes | - |
T8570 | 408-409 | -LRB- | denotes | ( |
T8571 | 409-411 | NN | denotes | pH |
T8572 | 412-415 | CD | denotes | 8.5 |
T8573 | 415-416 | -RRB- | denotes | ) |
T8574 | 416-418 | , | denotes | , |
T8575 | 418-421 | CD | denotes | 7.4 |
T8576 | 422-424 | NNS | denotes | mM |
T8577 | 425-430 | NN | denotes | MgCl2 |
T8578 | 430-432 | , | denotes | , |
T8579 | 432-435 | CD | denotes | 6.6 |
T8580 | 436-438 | NNS | denotes | mM |
T8581 | 439-442 | NN | denotes | ATP |
T8582 | 442-444 | , | denotes | , |
T8583 | 444-448 | CD | denotes | 0.65 |
T8584 | 449-451 | NNS | denotes | mM |
T8585 | 452-456 | NN | denotes | NADP |
T8586 | 456-458 | , | denotes | , |
T8587 | 458-462 | CD | denotes | 11.1 |
T8588 | 463-465 | NNS | denotes | mM |
T8589 | 466-482 | NN | denotes | monothioglycerol |
T8590 | 482-484 | , | denotes | , |
T8591 | 484-487 | CC | denotes | and |
T8592 | 488-489 | CD | denotes | 1 |
T8593 | 490-494 | NN | denotes | unit |
T8594 | 495-497 | IN | denotes | of |
T8595 | 498-505 | NN | denotes | glucose |
T8596 | 508-517 | NN | denotes | phosphate |
T8597 | 506-507 | CD | denotes | 6 |
T8598 | 507-508 | HYPH | denotes | - |
T8599 | 518-531 | NN | denotes | dehydrogenase |
T8600 | 531-532 | . | denotes | . |
T8601 | 532-725 | sentence | denotes | In the case of hexokinase activity measured in the presence of Cox11 and LD, the purified HKI was incubated with the recombinant proteins for 15 min at 4 °C before measurement of the activity. |
T8602 | 533-535 | IN | denotes | In |
T8603 | 631-640 | VBN | denotes | incubated |
T8604 | 536-539 | DT | denotes | the |
T8605 | 540-544 | NN | denotes | case |
T8606 | 545-547 | IN | denotes | of |
T8607 | 548-558 | NN | denotes | hexokinase |
T8608 | 559-567 | NN | denotes | activity |
T8609 | 568-576 | VBN | denotes | measured |
T8610 | 577-579 | IN | denotes | in |
T8611 | 580-583 | DT | denotes | the |
T8612 | 584-592 | NN | denotes | presence |
T8613 | 593-595 | IN | denotes | of |
T8614 | 596-601 | NN | denotes | Cox11 |
T8615 | 602-605 | CC | denotes | and |
T8616 | 606-608 | NN | denotes | LD |
T8617 | 608-610 | , | denotes | , |
T8618 | 610-613 | DT | denotes | the |
T8619 | 623-626 | NN | denotes | HKI |
T8620 | 614-622 | VBN | denotes | purified |
T8621 | 627-630 | VBD | denotes | was |
T8622 | 641-645 | IN | denotes | with |
T8623 | 646-649 | DT | denotes | the |
T8624 | 662-670 | NN | denotes | proteins |
T8625 | 650-661 | JJ | denotes | recombinant |
T8626 | 671-674 | IN | denotes | for |
T8627 | 675-677 | CD | denotes | 15 |
T8628 | 678-681 | NNS | denotes | min |
T8629 | 682-684 | IN | denotes | at |
T8630 | 685-686 | CD | denotes | 4 |
T8631 | 687-689 | NN | denotes | °C |
T8632 | 690-696 | IN | denotes | before |
T8633 | 697-708 | NN | denotes | measurement |
T8634 | 709-711 | IN | denotes | of |
T8635 | 712-715 | DT | denotes | the |
T8636 | 716-724 | NN | denotes | activity |
T8637 | 724-725 | . | denotes | . |
T8638 | 725-822 | sentence | denotes | The data were fitted directly into the Michaelis-Menten equation using SIGMAPLOT (SPSS Science). |
T8639 | 726-729 | DT | denotes | The |
T8640 | 730-734 | NNS | denotes | data |
T8641 | 740-746 | VBN | denotes | fitted |
T8642 | 735-739 | VBD | denotes | were |
T8643 | 747-755 | RB | denotes | directly |
T8644 | 756-760 | IN | denotes | into |
T8645 | 761-764 | DT | denotes | the |
T8646 | 782-790 | NN | denotes | equation |
T8647 | 765-774 | NNP | denotes | Michaelis |
T8648 | 775-781 | NNP | denotes | Menten |
T8649 | 774-775 | HYPH | denotes | - |
T8650 | 791-796 | VBG | denotes | using |
T8651 | 797-806 | NNP | denotes | SIGMAPLOT |
T8652 | 807-808 | -LRB- | denotes | ( |
T8653 | 813-820 | NNP | denotes | Science |
T8654 | 808-812 | NNP | denotes | SPSS |
T8655 | 820-821 | -RRB- | denotes | ) |
T8656 | 821-822 | . | denotes | . |
R5565 | T8488 | T8489 | nmod | Hexokinase,activity |
R5566 | T8489 | T8491 | nsubjpass | activity,determined |
R5567 | T8490 | T8488 | nummod | I,Hexokinase |
R5568 | T8492 | T8491 | auxpass | was,determined |
R5569 | T8493 | T8491 | advmod | spectrophotometrically,determined |
R5570 | T8494 | T8491 | prep | at,determined |
R5571 | T8495 | T8496 | nummod | 25,°C |
R5572 | T8496 | T8494 | pobj | °C,at |
R5573 | T8497 | T8491 | prep | by,determined |
R5574 | T8498 | T8499 | det | the,method |
R5575 | T8499 | T8497 | pobj | method,by |
R5576 | T8500 | T8499 | prep | of,method |
R5577 | T8501 | T8500 | pcomp | coupling,of |
R5578 | T8502 | T8503 | det | the,production |
R5579 | T8503 | T8501 | dobj | production,coupling |
R5580 | T8504 | T8505 | nmod | glucose,phosphate |
R5581 | T8505 | T8503 | compound | phosphate,production |
R5582 | T8506 | T8505 | punct | -,phosphate |
R5583 | T8507 | T8505 | nummod | 6,phosphate |
R5584 | T8508 | T8505 | punct | -,phosphate |
R5585 | T8509 | T8503 | prep | via,production |
R5586 | T8510 | T8511 | nmod | glucose,phosphate |
R5587 | T8511 | T8515 | compound | phosphate,dehydrogenase |
R5588 | T8512 | T8511 | punct | -,phosphate |
R5589 | T8513 | T8511 | nummod | 6,phosphate |
R5590 | T8514 | T8511 | punct | -,phosphate |
R5591 | T8515 | T8509 | pobj | dehydrogenase,via |
R5592 | T8516 | T8501 | prep | with,coupling |
R5593 | T8517 | T8518 | det | the,change |
R5594 | T8518 | T8516 | pobj | change,with |
R5595 | T8519 | T8518 | prep | in,change |
R5596 | T8520 | T8521 | det | the,absorbance |
R5597 | T8521 | T8519 | pobj | absorbance,in |
R5598 | T8522 | T8521 | prep | of,absorbance |
R5599 | T8523 | T8522 | pobj | NADPH,of |
R5600 | T8524 | T8518 | prep | at,change |
R5601 | T8525 | T8526 | nummod | 340,nm |
R5602 | T8526 | T8524 | pobj | nm,at |
R5603 | T8527 | T8497 | cc | and,by |
R5604 | T8528 | T8529 | mark | as,described |
R5605 | T8529 | T8497 | conj | described,by |
R5606 | T8530 | T8529 | agent | by,described |
R5607 | T8531 | T8532 | punct | [,66 |
R5608 | T8532 | T8530 | pobj | 66,by |
R5609 | T8533 | T8491 | punct | ],determined |
R5610 | T8534 | T8491 | punct | .,determined |
R5611 | T8536 | T8537 | det | The,reaction |
R5612 | T8537 | T8538 | nsubjpass | reaction,started |
R5613 | T8539 | T8538 | auxpass | was,started |
R5614 | T8540 | T8538 | agent | by,started |
R5615 | T8541 | T8542 | det | the,addition |
R5616 | T8542 | T8540 | pobj | addition,by |
R5617 | T8543 | T8542 | prep | of,addition |
R5618 | T8544 | T8545 | amod | purified,hexokinase |
R5619 | T8545 | T8543 | pobj | hexokinase,of |
R5620 | T8546 | T8545 | compound | brain,hexokinase |
R5621 | T8547 | T8545 | nummod | I,hexokinase |
R5622 | T8548 | T8549 | punct | (,μg |
R5623 | T8549 | T8545 | parataxis | μg,hexokinase |
R5624 | T8550 | T8549 | nummod | 0.24,μg |
R5625 | T8551 | T8549 | punct | ),μg |
R5626 | T8552 | T8553 | punct | (,gift |
R5627 | T8553 | T8545 | parataxis | gift,hexokinase |
R5628 | T8554 | T8553 | prep | from,gift |
R5629 | T8555 | T8556 | compound | J.,Wilson |
R5630 | T8556 | T8554 | pobj | Wilson,from |
R5631 | T8557 | T8553 | punct | ),gift |
R5632 | T8558 | T8542 | prep | to,addition |
R5633 | T8559 | T8560 | nummod | 1.0,ml |
R5634 | T8560 | T8558 | pobj | ml,to |
R5635 | T8561 | T8560 | prep | of,ml |
R5636 | T8562 | T8563 | compound | reaction,mixture |
R5637 | T8563 | T8561 | pobj | mixture,of |
R5638 | T8564 | T8560 | acl | containing,ml |
R5639 | T8565 | T8566 | nummod | 0.05,M |
R5640 | T8566 | T8567 | compound | M,HCl |
R5641 | T8567 | T8564 | dobj | HCl,containing |
R5642 | T8568 | T8567 | compound | Tris,HCl |
R5643 | T8569 | T8567 | punct | -,HCl |
R5644 | T8570 | T8571 | punct | (,pH |
R5645 | T8571 | T8567 | parataxis | pH,HCl |
R5646 | T8572 | T8571 | nummod | 8.5,pH |
R5647 | T8573 | T8571 | punct | ),pH |
R5648 | T8574 | T8567 | punct | ", ",HCl |
R5649 | T8575 | T8576 | nummod | 7.4,mM |
R5650 | T8576 | T8577 | compound | mM,MgCl2 |
R5651 | T8577 | T8567 | conj | MgCl2,HCl |
R5652 | T8578 | T8577 | punct | ", ",MgCl2 |
R5653 | T8579 | T8580 | nummod | 6.6,mM |
R5654 | T8580 | T8581 | compound | mM,ATP |
R5655 | T8581 | T8577 | conj | ATP,MgCl2 |
R5656 | T8582 | T8581 | punct | ", ",ATP |
R5657 | T8583 | T8584 | nummod | 0.65,mM |
R5658 | T8584 | T8585 | compound | mM,NADP |
R5659 | T8585 | T8581 | conj | NADP,ATP |
R5660 | T8586 | T8585 | punct | ", ",NADP |
R5661 | T8587 | T8588 | nummod | 11.1,mM |
R5662 | T8588 | T8589 | compound | mM,monothioglycerol |
R5663 | T8589 | T8585 | conj | monothioglycerol,NADP |
R5664 | T8590 | T8589 | punct | ", ",monothioglycerol |
R5665 | T8591 | T8589 | cc | and,monothioglycerol |
R5666 | T8592 | T8593 | nummod | 1,unit |
R5667 | T8593 | T8589 | conj | unit,monothioglycerol |
R5668 | T8594 | T8593 | prep | of,unit |
R5669 | T8595 | T8596 | nmod | glucose,phosphate |
R5670 | T8596 | T8599 | compound | phosphate,dehydrogenase |
R5671 | T8597 | T8596 | nummod | 6,phosphate |
R5672 | T8598 | T8596 | punct | -,phosphate |
R5673 | T8599 | T8594 | pobj | dehydrogenase,of |
R5674 | T8600 | T8538 | punct | .,started |
R5675 | T8602 | T8603 | prep | In,incubated |
R5676 | T8604 | T8605 | det | the,case |
R5677 | T8605 | T8602 | pobj | case,In |
R5678 | T8606 | T8605 | prep | of,case |
R5679 | T8607 | T8608 | compound | hexokinase,activity |
R5680 | T8608 | T8606 | pobj | activity,of |
R5681 | T8609 | T8608 | acl | measured,activity |
R5682 | T8610 | T8609 | prep | in,measured |
R5683 | T8611 | T8612 | det | the,presence |
R5684 | T8612 | T8610 | pobj | presence,in |
R5685 | T8613 | T8612 | prep | of,presence |
R5686 | T8614 | T8613 | pobj | Cox11,of |
R5687 | T8615 | T8614 | cc | and,Cox11 |
R5688 | T8616 | T8614 | conj | LD,Cox11 |
R5689 | T8617 | T8603 | punct | ", ",incubated |
R5690 | T8618 | T8619 | det | the,HKI |
R5691 | T8619 | T8603 | nsubjpass | HKI,incubated |
R5692 | T8620 | T8619 | amod | purified,HKI |
R5693 | T8621 | T8603 | auxpass | was,incubated |
R5694 | T8622 | T8603 | prep | with,incubated |
R5695 | T8623 | T8624 | det | the,proteins |
R5696 | T8624 | T8622 | pobj | proteins,with |
R5697 | T8625 | T8624 | amod | recombinant,proteins |
R5698 | T8626 | T8603 | prep | for,incubated |
R5699 | T8627 | T8628 | nummod | 15,min |
R5700 | T8628 | T8626 | pobj | min,for |
R5701 | T8629 | T8603 | prep | at,incubated |
R5702 | T8630 | T8631 | nummod | 4,°C |
R5703 | T8631 | T8629 | pobj | °C,at |
R5704 | T8632 | T8603 | prep | before,incubated |
R5705 | T8633 | T8632 | pobj | measurement,before |
R5706 | T8634 | T8633 | prep | of,measurement |
R5707 | T8635 | T8636 | det | the,activity |
R5708 | T8636 | T8634 | pobj | activity,of |
R5709 | T8637 | T8603 | punct | .,incubated |
R5710 | T8639 | T8640 | det | The,data |
R5711 | T8640 | T8641 | nsubjpass | data,fitted |
R5712 | T8642 | T8641 | auxpass | were,fitted |
R5713 | T8643 | T8641 | advmod | directly,fitted |
R5714 | T8644 | T8641 | prep | into,fitted |
R5715 | T8645 | T8646 | det | the,equation |
R5716 | T8646 | T8644 | pobj | equation,into |
R5717 | T8647 | T8648 | compound | Michaelis,Menten |
R5718 | T8648 | T8646 | compound | Menten,equation |
R5719 | T8649 | T8648 | punct | -,Menten |
R5720 | T8650 | T8641 | advcl | using,fitted |
R5721 | T8651 | T8650 | dobj | SIGMAPLOT,using |
R5722 | T8652 | T8653 | punct | (,Science |
R5723 | T8653 | T8651 | parataxis | Science,SIGMAPLOT |
R5724 | T8654 | T8653 | compound | SPSS,Science |
R5725 | T8655 | T8653 | punct | ),Science |
R5726 | T8656 | T8641 | punct | .,fitted |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8472 | 425-430 | CHEBI:6636 | denotes | MgCl2 |
T8460 | 0-10 | GO_EXT:0004396 | denotes | Hexokinase |
T8461 | 0-12 | PR_EXT:000008608 | denotes | Hexokinase I |
T8462 | 99-118 | CHEBI:14314 | denotes | glucose-6-phosphate |
T8463 | 134-153 | CHEBI:14314 | denotes | glucose-6-phosphate |
T8464 | 134-167 | GO_PR_EXT:glucose_6_phosphate_dehydrogenase | denotes | glucose-6-phosphate dehydrogenase |
T8465 | 205-210 | CHEBI_EXT:NADPH | denotes | NADPH |
T8466 | 300-305 | UBERON:0000955 | denotes | brain |
T8467 | 300-318 | PR_EXT:000008608 | denotes | brain hexokinase I |
T8468 | 306-316 | GO_EXT:0004396 | denotes | hexokinase |
T8469 | 373-380 | CHEBI:60004 | denotes | mixture |
T8470 | 399-403 | CHEBI:9754 | denotes | Tris |
T8471 | 404-407 | CHEBI:17883 | denotes | HCl |
T8473 | 439-442 | CHEBI_EXT:ATP | denotes | ATP |
T8474 | 452-456 | CHEBI_EXT:NADP | denotes | NADP |
T8475 | 466-482 | CHEBI:74537 | denotes | monothioglycerol |
T8476 | 498-517 | CHEBI:14314 | denotes | glucose 6-phosphate |
T8477 | 498-531 | GO_PR_EXT:glucose_6_phosphate_dehydrogenase | denotes | glucose 6-phosphate dehydrogenase |
T8478 | 548-558 | GO_EXT:0004396 | denotes | hexokinase |
T8479 | 596-601 | PR_EXT:000005770 | denotes | Cox11 |
T8480 | 623-626 | PR_EXT:000008608 | denotes | HKI |
T8481 | 650-661 | GO_SO_EXT:sequence_rearrangement_process | denotes | recombinant |
T8482 | 662-670 | CHEBI_PR_EXT:protein | denotes | proteins |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8445 | 0-12 | PR:000008608 | denotes | Hexokinase I |
T8446 | 99-118 | CHEBI:14314 | denotes | glucose-6-phosphate |
T8447 | 134-153 | CHEBI:14314 | denotes | glucose-6-phosphate |
T8448 | 300-305 | UBERON:0000955 | denotes | brain |
T8449 | 300-318 | PR:000008608 | denotes | brain hexokinase I |
T8450 | 373-380 | CHEBI:60004 | denotes | mixture |
T8451 | 399-403 | CHEBI:9754 | denotes | Tris |
T8452 | 404-407 | CHEBI:17883 | denotes | HCl |
T8453 | 425-430 | CHEBI:6636 | denotes | MgCl2 |
T8454 | 466-482 | CHEBI:74537 | denotes | monothioglycerol |
T8455 | 498-517 | CHEBI:14314 | denotes | glucose 6-phosphate |
T8456 | 596-601 | PR:000005770 | denotes | Cox11 |
T8457 | 623-626 | PR:000008608 | denotes | HKI |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
17069463-2740289-85858879 | 242-244 | 2740289 | denotes | 66 |
T67368 | 242-244 | 2740289 | denotes | 66 |