Id |
Subject |
Object |
Predicate |
Lexical cue |
T3130 |
11-17 |
NN |
denotes |
Family |
T3131 |
18-25 |
NN |
denotes |
history |
T3132 |
30-32 |
VBZ |
denotes |
is |
T3133 |
26-27 |
-LRB- |
denotes |
[ |
T3134 |
27-28 |
CD |
denotes |
1 |
T3135 |
28-29 |
-RRB- |
denotes |
] |
T3136 |
33-36 |
DT |
denotes |
the |
T3137 |
52-58 |
NN |
denotes |
factor |
T3138 |
37-46 |
JJS |
denotes |
strongest |
T3139 |
47-51 |
NN |
denotes |
risk |
T3140 |
59-62 |
IN |
denotes |
for |
T3141 |
63-77 |
JJ |
denotes |
cardiovascular |
T3142 |
78-86 |
NNS |
denotes |
diseases |
T3143 |
87-88 |
-LRB- |
denotes |
( |
T3144 |
88-91 |
NNS |
denotes |
CVD |
T3145 |
91-92 |
-RRB- |
denotes |
) |
T3146 |
92-93 |
. |
denotes |
. |
T3147 |
93-226 |
sentence |
denotes |
While a number of genetic mutations have been identified, these account for only a small percentage of the CVD in human populations. |
T3148 |
94-99 |
IN |
denotes |
While |
T3149 |
140-150 |
VBN |
denotes |
identified |
T3150 |
100-101 |
DT |
denotes |
a |
T3151 |
102-108 |
NN |
denotes |
number |
T3152 |
109-111 |
IN |
denotes |
of |
T3153 |
112-119 |
JJ |
denotes |
genetic |
T3154 |
120-129 |
NNS |
denotes |
mutations |
T3155 |
130-134 |
VBP |
denotes |
have |
T3156 |
135-139 |
VBN |
denotes |
been |
T3157 |
158-165 |
VBP |
denotes |
account |
T3158 |
150-152 |
, |
denotes |
, |
T3159 |
152-157 |
DT |
denotes |
these |
T3160 |
166-169 |
IN |
denotes |
for |
T3161 |
170-174 |
RB |
denotes |
only |
T3162 |
183-193 |
NN |
denotes |
percentage |
T3163 |
175-176 |
DT |
denotes |
a |
T3164 |
177-182 |
JJ |
denotes |
small |
T3165 |
194-196 |
IN |
denotes |
of |
T3166 |
197-200 |
DT |
denotes |
the |
T3167 |
201-204 |
NNS |
denotes |
CVD |
T3168 |
205-207 |
IN |
denotes |
in |
T3169 |
208-213 |
JJ |
denotes |
human |
T3170 |
214-225 |
NNS |
denotes |
populations |
T3171 |
225-226 |
. |
denotes |
. |
T3172 |
226-471 |
sentence |
denotes |
Thrombus formation on fissured atherosclerotic plaques is the precipitating event in the transition from a stable or subclinical atherosclerotic disease and leads to acute myocardial infarction, ischemic stroke or peripheral arterial occlusion. |
T3173 |
227-235 |
NN |
denotes |
Thrombus |
T3174 |
236-245 |
NN |
denotes |
formation |
T3175 |
282-284 |
VBZ |
denotes |
is |
T3176 |
246-248 |
IN |
denotes |
on |
T3177 |
249-257 |
VBN |
denotes |
fissured |
T3178 |
274-281 |
NNS |
denotes |
plaques |
T3179 |
258-273 |
JJ |
denotes |
atherosclerotic |
T3180 |
285-288 |
DT |
denotes |
the |
T3181 |
303-308 |
NN |
denotes |
event |
T3182 |
289-302 |
VBG |
denotes |
precipitating |
T3183 |
309-311 |
IN |
denotes |
in |
T3184 |
312-315 |
DT |
denotes |
the |
T3185 |
316-326 |
NN |
denotes |
transition |
T3186 |
327-331 |
IN |
denotes |
from |
T3187 |
332-333 |
DT |
denotes |
a |
T3188 |
372-379 |
NN |
denotes |
disease |
T3189 |
334-340 |
JJ |
denotes |
stable |
T3190 |
341-343 |
CC |
denotes |
or |
T3191 |
344-355 |
JJ |
denotes |
subclinical |
T3192 |
356-371 |
JJ |
denotes |
atherosclerotic |
T3193 |
380-383 |
CC |
denotes |
and |
T3194 |
384-389 |
VBZ |
denotes |
leads |
T3195 |
390-392 |
IN |
denotes |
to |
T3196 |
393-398 |
JJ |
denotes |
acute |
T3197 |
410-420 |
NN |
denotes |
infarction |
T3198 |
399-409 |
JJ |
denotes |
myocardial |
T3199 |
420-422 |
, |
denotes |
, |
T3200 |
422-430 |
JJ |
denotes |
ischemic |
T3201 |
431-437 |
NN |
denotes |
stroke |
T3202 |
438-440 |
CC |
denotes |
or |
T3203 |
441-451 |
JJ |
denotes |
peripheral |
T3204 |
452-460 |
JJ |
denotes |
arterial |
T3205 |
461-470 |
NN |
denotes |
occlusion |
T3206 |
470-471 |
. |
denotes |
. |
T3207 |
471-596 |
sentence |
denotes |
Arterial and venous thrombosis are complex responses and are influenced by multiple genetic and environmental factors [2-5]. |
T3208 |
472-480 |
JJ |
denotes |
Arterial |
T3209 |
492-502 |
NN |
denotes |
thrombosis |
T3210 |
481-484 |
CC |
denotes |
and |
T3211 |
485-491 |
JJ |
denotes |
venous |
T3212 |
503-506 |
VBP |
denotes |
are |
T3213 |
507-514 |
JJ |
denotes |
complex |
T3214 |
515-524 |
NNS |
denotes |
responses |
T3215 |
525-528 |
CC |
denotes |
and |
T3216 |
529-532 |
VBP |
denotes |
are |
T3217 |
533-543 |
VBN |
denotes |
influenced |
T3218 |
544-546 |
IN |
denotes |
by |
T3219 |
547-555 |
JJ |
denotes |
multiple |
T3220 |
582-589 |
NNS |
denotes |
factors |
T3221 |
556-563 |
JJ |
denotes |
genetic |
T3222 |
564-567 |
CC |
denotes |
and |
T3223 |
568-581 |
JJ |
denotes |
environmental |
T3224 |
590-591 |
-LRB- |
denotes |
[ |
T3225 |
591-592 |
CD |
denotes |
2 |
T3226 |
592-593 |
SYM |
denotes |
- |
T3227 |
593-594 |
CD |
denotes |
5 |
T3228 |
594-595 |
-RRB- |
denotes |
] |
T3229 |
595-596 |
. |
denotes |
. |
T3230 |
596-878 |
sentence |
denotes |
Polymorphisms and mutations in coagulation factors, fibrinolytic factors, platelet surface receptors, methylenetetrahydrofalate reductase, endothelial nitric oxide synthase, and antioxidant enzymes have been implicated as genetic determinants of susceptibility to thrombosis [6,7]. |
T3231 |
597-610 |
NNS |
denotes |
Polymorphisms |
T3232 |
805-815 |
VBN |
denotes |
implicated |
T3233 |
611-614 |
CC |
denotes |
and |
T3234 |
615-624 |
NNS |
denotes |
mutations |
T3235 |
625-627 |
IN |
denotes |
in |
T3236 |
628-639 |
NN |
denotes |
coagulation |
T3237 |
640-647 |
NNS |
denotes |
factors |
T3238 |
647-649 |
, |
denotes |
, |
T3239 |
649-661 |
JJ |
denotes |
fibrinolytic |
T3240 |
662-669 |
NNS |
denotes |
factors |
T3241 |
669-671 |
, |
denotes |
, |
T3242 |
671-679 |
NN |
denotes |
platelet |
T3243 |
680-687 |
NN |
denotes |
surface |
T3244 |
688-697 |
NNS |
denotes |
receptors |
T3245 |
697-699 |
, |
denotes |
, |
T3246 |
699-724 |
NN |
denotes |
methylenetetrahydrofalate |
T3247 |
725-734 |
NN |
denotes |
reductase |
T3248 |
734-736 |
, |
denotes |
, |
T3249 |
736-747 |
JJ |
denotes |
endothelial |
T3250 |
761-769 |
NN |
denotes |
synthase |
T3251 |
748-754 |
JJ |
denotes |
nitric |
T3252 |
755-760 |
NN |
denotes |
oxide |
T3253 |
769-771 |
, |
denotes |
, |
T3254 |
771-774 |
CC |
denotes |
and |
T3255 |
775-786 |
JJ |
denotes |
antioxidant |
T3256 |
787-794 |
NNS |
denotes |
enzymes |
T3257 |
795-799 |
VBP |
denotes |
have |
T3258 |
800-804 |
VBN |
denotes |
been |
T3259 |
816-818 |
IN |
denotes |
as |
T3260 |
819-826 |
JJ |
denotes |
genetic |
T3261 |
827-839 |
NNS |
denotes |
determinants |
T3262 |
840-842 |
IN |
denotes |
of |
T3263 |
843-857 |
NN |
denotes |
susceptibility |
T3264 |
858-860 |
IN |
denotes |
to |
T3265 |
861-871 |
NN |
denotes |
thrombosis |
T3266 |
872-873 |
-LRB- |
denotes |
[ |
T3267 |
875-876 |
CD |
denotes |
7 |
T3268 |
873-874 |
CD |
denotes |
6 |
T3269 |
874-875 |
, |
denotes |
, |
T3270 |
876-877 |
-RRB- |
denotes |
] |
T3271 |
877-878 |
. |
denotes |
. |
T3272 |
878-972 |
sentence |
denotes |
Great strides have been made in the diagnosis and treatment of thrombosis in the last decade. |
T3273 |
879-884 |
JJ |
denotes |
Great |
T3274 |
885-892 |
NNS |
denotes |
strides |
T3275 |
903-907 |
VBN |
denotes |
made |
T3276 |
893-897 |
VBP |
denotes |
have |
T3277 |
898-902 |
VBN |
denotes |
been |
T3278 |
908-910 |
IN |
denotes |
in |
T3279 |
911-914 |
DT |
denotes |
the |
T3280 |
915-924 |
NN |
denotes |
diagnosis |
T3281 |
925-928 |
CC |
denotes |
and |
T3282 |
929-938 |
NN |
denotes |
treatment |
T3283 |
939-941 |
IN |
denotes |
of |
T3284 |
942-952 |
NN |
denotes |
thrombosis |
T3285 |
953-955 |
IN |
denotes |
in |
T3286 |
956-959 |
DT |
denotes |
the |
T3287 |
965-971 |
NN |
denotes |
decade |
T3288 |
960-964 |
JJ |
denotes |
last |
T3289 |
971-972 |
. |
denotes |
. |
T3290 |
972-1152 |
sentence |
denotes |
However, strategies to prevent thrombosis have lagged far behind due, in part, to the contribution of multiple, and as yet undefined, genetic factors that lead to thrombotic risk. |
T3291 |
973-980 |
RB |
denotes |
However |
T3292 |
1020-1026 |
VBN |
denotes |
lagged |
T3293 |
980-982 |
, |
denotes |
, |
T3294 |
982-992 |
NNS |
denotes |
strategies |
T3295 |
993-995 |
TO |
denotes |
to |
T3296 |
996-1003 |
VB |
denotes |
prevent |
T3297 |
1004-1014 |
NN |
denotes |
thrombosis |
T3298 |
1015-1019 |
VBP |
denotes |
have |
T3299 |
1027-1030 |
RB |
denotes |
far |
T3300 |
1031-1037 |
RB |
denotes |
behind |
T3301 |
1038-1041 |
IN |
denotes |
due |
T3302 |
1041-1043 |
, |
denotes |
, |
T3303 |
1043-1045 |
IN |
denotes |
in |
T3304 |
1046-1050 |
JJ |
denotes |
part |
T3305 |
1050-1052 |
, |
denotes |
, |
T3306 |
1052-1054 |
IN |
denotes |
to |
T3307 |
1055-1058 |
DT |
denotes |
the |
T3308 |
1059-1071 |
NN |
denotes |
contribution |
T3309 |
1072-1074 |
IN |
denotes |
of |
T3310 |
1075-1083 |
JJ |
denotes |
multiple |
T3311 |
1115-1122 |
NNS |
denotes |
factors |
T3312 |
1083-1085 |
, |
denotes |
, |
T3313 |
1085-1088 |
CC |
denotes |
and |
T3314 |
1089-1091 |
RB |
denotes |
as |
T3315 |
1092-1095 |
RB |
denotes |
yet |
T3316 |
1096-1105 |
JJ |
denotes |
undefined |
T3317 |
1105-1107 |
, |
denotes |
, |
T3318 |
1107-1114 |
JJ |
denotes |
genetic |
T3319 |
1123-1127 |
WDT |
denotes |
that |
T3320 |
1128-1132 |
VBP |
denotes |
lead |
T3321 |
1133-1135 |
IN |
denotes |
to |
T3322 |
1136-1146 |
JJ |
denotes |
thrombotic |
T3323 |
1147-1151 |
NN |
denotes |
risk |
T3324 |
1151-1152 |
. |
denotes |
. |
T3325 |
1152-1362 |
sentence |
denotes |
Moreover, it remains unclear how genetic background influences the function of molecules and pathways known to regulate thrombus formation and lysis and, thereby, contributes to the risk of thrombotic disease. |
T3326 |
1153-1161 |
RB |
denotes |
Moreover |
T3327 |
1166-1173 |
VBZ |
denotes |
remains |
T3328 |
1161-1163 |
, |
denotes |
, |
T3329 |
1163-1165 |
PRP |
denotes |
it |
T3330 |
1174-1181 |
JJ |
denotes |
unclear |
T3331 |
1182-1185 |
WRB |
denotes |
how |
T3332 |
1205-1215 |
VBZ |
denotes |
influences |
T3333 |
1186-1193 |
JJ |
denotes |
genetic |
T3334 |
1194-1204 |
NN |
denotes |
background |
T3335 |
1216-1219 |
DT |
denotes |
the |
T3336 |
1220-1228 |
NN |
denotes |
function |
T3337 |
1229-1231 |
IN |
denotes |
of |
T3338 |
1232-1241 |
NNS |
denotes |
molecules |
T3339 |
1242-1245 |
CC |
denotes |
and |
T3340 |
1246-1254 |
NNS |
denotes |
pathways |
T3341 |
1255-1260 |
VBN |
denotes |
known |
T3342 |
1261-1263 |
TO |
denotes |
to |
T3343 |
1264-1272 |
VB |
denotes |
regulate |
T3344 |
1273-1281 |
NN |
denotes |
thrombus |
T3345 |
1282-1291 |
NN |
denotes |
formation |
T3346 |
1292-1295 |
CC |
denotes |
and |
T3347 |
1296-1301 |
NN |
denotes |
lysis |
T3348 |
1302-1305 |
CC |
denotes |
and |
T3349 |
1305-1307 |
, |
denotes |
, |
T3350 |
1307-1314 |
RB |
denotes |
thereby |
T3351 |
1316-1327 |
VBZ |
denotes |
contributes |
T3352 |
1314-1316 |
, |
denotes |
, |
T3353 |
1328-1330 |
IN |
denotes |
to |
T3354 |
1331-1334 |
DT |
denotes |
the |
T3355 |
1335-1339 |
NN |
denotes |
risk |
T3356 |
1340-1342 |
IN |
denotes |
of |
T3357 |
1343-1353 |
JJ |
denotes |
thrombotic |
T3358 |
1354-1361 |
NN |
denotes |
disease |
T3359 |
1361-1362 |
. |
denotes |
. |
T3360 |
1362-1528 |
sentence |
denotes |
Many of the available inbred mouse strains, such as C57BL/6J (B6) and A/J, have been classified as resistant or susceptible to particular complex diseases (Table 1). |
T3361 |
1363-1367 |
JJ |
denotes |
Many |
T3362 |
1448-1458 |
VBN |
denotes |
classified |
T3363 |
1368-1370 |
IN |
denotes |
of |
T3364 |
1371-1374 |
DT |
denotes |
the |
T3365 |
1398-1405 |
NNS |
denotes |
strains |
T3366 |
1375-1384 |
JJ |
denotes |
available |
T3367 |
1385-1391 |
JJ |
denotes |
inbred |
T3368 |
1392-1397 |
NN |
denotes |
mouse |
T3369 |
1405-1407 |
, |
denotes |
, |
T3370 |
1407-1411 |
JJ |
denotes |
such |
T3371 |
1412-1414 |
IN |
denotes |
as |
T3372 |
1415-1420 |
NN |
denotes |
C57BL |
T3373 |
1421-1423 |
NN |
denotes |
6J |
T3374 |
1420-1421 |
HYPH |
denotes |
/ |
T3375 |
1424-1425 |
-LRB- |
denotes |
( |
T3376 |
1425-1427 |
NN |
denotes |
B6 |
T3377 |
1427-1428 |
-RRB- |
denotes |
) |
T3378 |
1429-1432 |
CC |
denotes |
and |
T3379 |
1433-1434 |
NN |
denotes |
A |
T3380 |
1435-1436 |
NN |
denotes |
J |
T3381 |
1434-1435 |
HYPH |
denotes |
/ |
T3382 |
1436-1438 |
, |
denotes |
, |
T3383 |
1438-1442 |
VBP |
denotes |
have |
T3384 |
1443-1447 |
VBN |
denotes |
been |
T3385 |
1459-1461 |
IN |
denotes |
as |
T3386 |
1462-1471 |
JJ |
denotes |
resistant |
T3387 |
1472-1474 |
CC |
denotes |
or |
T3388 |
1475-1486 |
JJ |
denotes |
susceptible |
T3389 |
1487-1489 |
IN |
denotes |
to |
T3390 |
1490-1500 |
JJ |
denotes |
particular |
T3391 |
1509-1517 |
NNS |
denotes |
diseases |
T3392 |
1501-1508 |
JJ |
denotes |
complex |
T3393 |
1518-1519 |
-LRB- |
denotes |
( |
T3394 |
1519-1524 |
NN |
denotes |
Table |
T3395 |
1525-1526 |
CD |
denotes |
1 |
T3396 |
1526-1527 |
-RRB- |
denotes |
) |
T3397 |
1527-1528 |
. |
denotes |
. |
T3398 |
1528-1853 |
sentence |
denotes |
These two strains have diverse responses to diet-induced obesity [8] (B6 susceptible; A/J resistant), diet-induced atherosclerosis (B6 susceptible; A/J resistant) [9], arterial ligation-induced neointimal hyperplasia (B6 resistant; A/J resistant), and ligation induced vessel remodeling (B6 resistant; A/J susceptible) [10]. |
T3399 |
1529-1534 |
DT |
denotes |
These |
T3400 |
1539-1546 |
NNS |
denotes |
strains |
T3401 |
1535-1538 |
CD |
denotes |
two |
T3402 |
1547-1551 |
VBP |
denotes |
have |
T3403 |
1552-1559 |
JJ |
denotes |
diverse |
T3404 |
1560-1569 |
NNS |
denotes |
responses |
T3405 |
1570-1572 |
IN |
denotes |
to |
T3406 |
1573-1577 |
NN |
denotes |
diet |
T3407 |
1578-1585 |
VBN |
denotes |
induced |
T3408 |
1577-1578 |
HYPH |
denotes |
- |
T3409 |
1586-1593 |
NN |
denotes |
obesity |
T3410 |
1594-1595 |
-LRB- |
denotes |
[ |
T3411 |
1595-1596 |
CD |
denotes |
8 |
T3412 |
1596-1597 |
-RRB- |
denotes |
] |
T3413 |
1598-1599 |
-LRB- |
denotes |
( |
T3414 |
1619-1628 |
JJ |
denotes |
resistant |
T3415 |
1599-1601 |
NN |
denotes |
B6 |
T3416 |
1602-1613 |
JJ |
denotes |
susceptible |
T3417 |
1613-1614 |
: |
denotes |
; |
T3418 |
1615-1616 |
NN |
denotes |
A |
T3419 |
1617-1618 |
NN |
denotes |
J |
T3420 |
1616-1617 |
HYPH |
denotes |
/ |
T3421 |
1628-1629 |
-RRB- |
denotes |
) |
T3422 |
1629-1631 |
, |
denotes |
, |
T3423 |
1631-1635 |
NN |
denotes |
diet |
T3424 |
1636-1643 |
VBN |
denotes |
induced |
T3425 |
1635-1636 |
HYPH |
denotes |
- |
T3426 |
1644-1659 |
NN |
denotes |
atherosclerosis |
T3427 |
1660-1661 |
-LRB- |
denotes |
( |
T3428 |
1681-1690 |
JJ |
denotes |
resistant |
T3429 |
1661-1663 |
NN |
denotes |
B6 |
T3430 |
1664-1675 |
JJ |
denotes |
susceptible |
T3431 |
1675-1676 |
: |
denotes |
; |
T3432 |
1677-1678 |
NN |
denotes |
A |
T3433 |
1679-1680 |
NN |
denotes |
J |
T3434 |
1678-1679 |
HYPH |
denotes |
/ |
T3435 |
1690-1691 |
-RRB- |
denotes |
) |
T3436 |
1692-1693 |
-LRB- |
denotes |
[ |
T3437 |
1693-1694 |
CD |
denotes |
9 |
T3438 |
1694-1695 |
-RRB- |
denotes |
] |
T3439 |
1695-1697 |
, |
denotes |
, |
T3440 |
1697-1705 |
JJ |
denotes |
arterial |
T3441 |
1706-1714 |
NN |
denotes |
ligation |
T3442 |
1715-1722 |
VBN |
denotes |
induced |
T3443 |
1714-1715 |
HYPH |
denotes |
- |
T3444 |
1734-1745 |
NN |
denotes |
hyperplasia |
T3445 |
1723-1733 |
JJ |
denotes |
neointimal |
T3446 |
1746-1747 |
-LRB- |
denotes |
( |
T3447 |
1765-1774 |
JJ |
denotes |
resistant |
T3448 |
1747-1749 |
NN |
denotes |
B6 |
T3449 |
1750-1759 |
JJ |
denotes |
resistant |
T3450 |
1759-1760 |
: |
denotes |
; |
T3451 |
1761-1762 |
NN |
denotes |
A |
T3452 |
1763-1764 |
NN |
denotes |
J |
T3453 |
1762-1763 |
HYPH |
denotes |
/ |
T3454 |
1774-1775 |
-RRB- |
denotes |
) |
T3455 |
1775-1777 |
, |
denotes |
, |
T3456 |
1777-1780 |
CC |
denotes |
and |
T3457 |
1781-1789 |
NN |
denotes |
ligation |
T3458 |
1790-1797 |
VBN |
denotes |
induced |
T3459 |
1805-1815 |
NN |
denotes |
remodeling |
T3460 |
1798-1804 |
NN |
denotes |
vessel |
T3461 |
1816-1817 |
-LRB- |
denotes |
( |
T3462 |
1849-1851 |
CD |
denotes |
10 |
T3463 |
1817-1819 |
NN |
denotes |
B6 |
T3464 |
1820-1829 |
JJ |
denotes |
resistant |
T3467 |
1833-1834 |
NN |
denotes |
J |
T3468 |
1832-1833 |
HYPH |
denotes |
/ |
T3469 |
1835-1846 |
JJ |
denotes |
susceptible |
T3470 |
1846-1847 |
-RRB- |
denotes |
) |
T3471 |
1848-1849 |
-LRB- |
denotes |
[ |
T3472 |
1851-1852 |
-RRB- |
denotes |
] |
T3473 |
1852-1853 |
. |
denotes |
. |
T3474 |
1853-1979 |
sentence |
denotes |
These conditions are predisposing to thrombosis per se, but these mice have not been systematically evaluated for thrombosis. |
T3475 |
1854-1859 |
DT |
denotes |
These |
T3476 |
1860-1870 |
NNS |
denotes |
conditions |
T3477 |
1871-1874 |
VBP |
denotes |
are |
T3478 |
1875-1887 |
VBG |
denotes |
predisposing |
T3479 |
1888-1890 |
IN |
denotes |
to |
T3480 |
1891-1901 |
NN |
denotes |
thrombosis |
T3481 |
1902-1905 |
FW |
denotes |
per |
T3482 |
1906-1908 |
FW |
denotes |
se |
T3483 |
1908-1910 |
, |
denotes |
, |
T3484 |
1910-1913 |
CC |
denotes |
but |
T3485 |
1914-1919 |
DT |
denotes |
these |
T3486 |
1920-1924 |
NNS |
denotes |
mice |
T3487 |
1954-1963 |
VBN |
denotes |
evaluated |
T3488 |
1925-1929 |
VBP |
denotes |
have |
T3489 |
1930-1933 |
RB |
denotes |
not |
T3490 |
1934-1938 |
VBN |
denotes |
been |
T3491 |
1939-1953 |
RB |
denotes |
systematically |
T3492 |
1964-1967 |
IN |
denotes |
for |
T3493 |
1968-1978 |
NN |
denotes |
thrombosis |
T3494 |
1978-1979 |
. |
denotes |
. |
T3495 |
1979-2116 |
sentence |
denotes |
Clot formation and lysis, which ultimately determine thrombosis, requires platelet aggregation, coagulation, and fibrinolytic functions. |
T3496 |
1980-1984 |
NN |
denotes |
Clot |
T3497 |
1985-1994 |
NN |
denotes |
formation |
T3498 |
2045-2053 |
VBZ |
denotes |
requires |
T3499 |
1995-1998 |
CC |
denotes |
and |
T3500 |
1999-2004 |
NN |
denotes |
lysis |
T3501 |
2004-2006 |
, |
denotes |
, |
T3502 |
2006-2011 |
WDT |
denotes |
which |
T3503 |
2023-2032 |
VBP |
denotes |
determine |
T3504 |
2012-2022 |
RB |
denotes |
ultimately |
T3505 |
2033-2043 |
NN |
denotes |
thrombosis |
T3506 |
2043-2045 |
, |
denotes |
, |
T3507 |
2054-2062 |
NN |
denotes |
platelet |
T3508 |
2063-2074 |
NN |
denotes |
aggregation |
T3509 |
2074-2076 |
, |
denotes |
, |
T3510 |
2076-2087 |
NN |
denotes |
coagulation |
T3511 |
2087-2089 |
, |
denotes |
, |
T3512 |
2089-2092 |
CC |
denotes |
and |
T3513 |
2093-2105 |
JJ |
denotes |
fibrinolytic |
T3514 |
2106-2115 |
NNS |
denotes |
functions |
T3515 |
2115-2116 |
. |
denotes |
. |
T3516 |
2116-2213 |
sentence |
denotes |
Interactions among these pathways may occur and additional factors may modulate these processes. |
T3517 |
2117-2129 |
NNS |
denotes |
Interactions |
T3518 |
2155-2160 |
VB |
denotes |
occur |
T3519 |
2130-2135 |
IN |
denotes |
among |
T3520 |
2136-2141 |
DT |
denotes |
these |
T3521 |
2142-2150 |
NNS |
denotes |
pathways |
T3522 |
2151-2154 |
MD |
denotes |
may |
T3523 |
2161-2164 |
CC |
denotes |
and |
T3524 |
2165-2175 |
JJ |
denotes |
additional |
T3525 |
2176-2183 |
NNS |
denotes |
factors |
T3526 |
2188-2196 |
VB |
denotes |
modulate |
T3527 |
2184-2187 |
MD |
denotes |
may |
T3528 |
2197-2202 |
DT |
denotes |
these |
T3529 |
2203-2212 |
NNS |
denotes |
processes |
T3530 |
2212-2213 |
. |
denotes |
. |
T3531 |
2213-2404 |
sentence |
denotes |
Identification of novel modulators and factors of these pathways can be identified by associating the phenotype with a location(s) on a specific chromosome, a quantitative trait locus (QTL). |
T3532 |
2214-2228 |
NN |
denotes |
Identification |
T3533 |
2286-2296 |
VBN |
denotes |
identified |
T3534 |
2229-2231 |
IN |
denotes |
of |
T3535 |
2232-2237 |
JJ |
denotes |
novel |
T3536 |
2238-2248 |
NNS |
denotes |
modulators |
T3537 |
2249-2252 |
CC |
denotes |
and |
T3538 |
2253-2260 |
NNS |
denotes |
factors |
T3539 |
2261-2263 |
IN |
denotes |
of |
T3540 |
2264-2269 |
DT |
denotes |
these |
T3541 |
2270-2278 |
NNS |
denotes |
pathways |
T3542 |
2279-2282 |
MD |
denotes |
can |
T3543 |
2283-2285 |
VB |
denotes |
be |
T3544 |
2297-2299 |
IN |
denotes |
by |
T3545 |
2300-2311 |
VBG |
denotes |
associating |
T3546 |
2312-2315 |
DT |
denotes |
the |
T3547 |
2316-2325 |
NN |
denotes |
phenotype |
T3548 |
2326-2330 |
IN |
denotes |
with |
T3549 |
2331-2332 |
DT |
denotes |
a |
T3550 |
2333-2341 |
NN |
denotes |
location |
T3551 |
2341-2342 |
-LRB- |
denotes |
( |
T3552 |
2342-2343 |
AFX |
denotes |
s |
T3553 |
2343-2344 |
-RRB- |
denotes |
) |
T3554 |
2345-2347 |
IN |
denotes |
on |
T3555 |
2348-2349 |
DT |
denotes |
a |
T3556 |
2359-2369 |
NN |
denotes |
chromosome |
T3557 |
2350-2358 |
JJ |
denotes |
specific |
T3558 |
2369-2371 |
, |
denotes |
, |
T3559 |
2371-2372 |
DT |
denotes |
a |
T3560 |
2392-2397 |
NN |
denotes |
locus |
T3561 |
2373-2385 |
JJ |
denotes |
quantitative |
T3562 |
2386-2391 |
NN |
denotes |
trait |
T3563 |
2398-2399 |
-LRB- |
denotes |
( |
T3564 |
2399-2402 |
NN |
denotes |
QTL |
T3565 |
2402-2403 |
-RRB- |
denotes |
) |
T3566 |
2403-2404 |
. |
denotes |
. |
T3567 |
2404-2405 |
sentence |
denotes |
|
T3928 |
4707-4708 |
. |
denotes |
. |
T3927 |
4697-4707 |
NN |
denotes |
thrombosis |
T3926 |
4693-4696 |
CC |
denotes |
and |
T3925 |
4681-4692 |
NN |
denotes |
haemostasis |
T3924 |
4668-4680 |
JJ |
denotes |
pathological |
T3923 |
4665-4667 |
IN |
denotes |
to |
T3922 |
4650-4664 |
NN |
denotes |
susceptibility |
T3921 |
4647-4649 |
IN |
denotes |
of |
T3920 |
4626-4633 |
JJ |
denotes |
genetic |
T3919 |
4634-4646 |
NNS |
denotes |
determinants |
T3918 |
4614-4625 |
JJ |
denotes |
independent |
T3917 |
4605-4613 |
VB |
denotes |
identify |
T3916 |
4602-4604 |
TO |
denotes |
to |
T3915 |
4593-4601 |
JJ |
denotes |
possible |
T3914 |
4583-4589 |
MD |
denotes |
should |
T3913 |
4580-4582 |
PRP |
denotes |
it |
T3912 |
4578-4580 |
, |
denotes |
, |
T3911 |
4590-4592 |
VB |
denotes |
be |
T3910 |
4574-4578 |
RB |
denotes |
Thus |
T3909 |
4573-4708 |
sentence |
denotes |
Thus, it should be possible to identify independent genetic determinants of susceptibility to pathological haemostasis and thrombosis. |
T3908 |
4572-4573 |
. |
denotes |
. |
T3907 |
4566-4567 |
HYPH |
denotes |
/ |
T3906 |
4567-4568 |
NN |
denotes |
J |
T3905 |
4565-4566 |
NN |
denotes |
A |
T3904 |
4569-4572 |
NN |
denotes |
QTL |
T3903 |
4561-4564 |
DT |
denotes |
the |
T3902 |
4555-4560 |
IN |
denotes |
among |
T3901 |
4533-4545 |
NNS |
denotes |
interactions |
T3900 |
4546-4554 |
VBD |
denotes |
occurred |
T3899 |
4528-4532 |
IN |
denotes |
that |
T3898 |
4518-4527 |
VBD |
denotes |
suggested |
T3897 |
4514-4517 |
CC |
denotes |
and |
T3896 |
4512-4514 |
, |
denotes |
, |
T3895 |
4499-4501 |
NN |
denotes |
B6 |
T3894 |
4502-4512 |
NN |
denotes |
background |
T3893 |
4495-4498 |
DT |
denotes |
the |
T3892 |
4492-4494 |
IN |
denotes |
in |
T3891 |
4479-4482 |
VBD |
denotes |
was |
T3890 |
4477-4479 |
, |
denotes |
, |
T3889 |
4468-4477 |
NN |
denotes |
occlusion |
T3888 |
4459-4467 |
JJ |
denotes |
arterial |
T3887 |
4455-4458 |
CC |
denotes |
and |
T3886 |
4450-4454 |
NN |
denotes |
time |
T3885 |
4439-4449 |
NN |
denotes |
rebleeding |
T3884 |
4437-4439 |
, |
denotes |
, |
T3883 |
4424-4425 |
HYPH |
denotes |
/ |
T3882 |
4425-4426 |
NN |
denotes |
J |
T3881 |
4423-4424 |
NN |
denotes |
A |
T3880 |
4427-4437 |
NNS |
denotes |
phenotypes |
T3879 |
4419-4422 |
DT |
denotes |
the |
T3878 |
4416-4418 |
IN |
denotes |
of |
T3877 |
4405-4415 |
NN |
denotes |
expression |
T3876 |
4403-4405 |
, |
denotes |
, |
T3875 |
4400-4403 |
NN |
denotes |
CSS |
T3874 |
4396-4399 |
DT |
denotes |
the |
T3873 |
4393-4395 |
IN |
denotes |
in |
T3872 |
4391-4393 |
, |
denotes |
, |
T3871 |
4383-4391 |
NN |
denotes |
addition |
T3870 |
4483-4491 |
VBN |
denotes |
modified |
T3869 |
4380-4382 |
IN |
denotes |
In |
T3868 |
4379-4573 |
sentence |
denotes |
In addition, in the CSS, expression of the A/J phenotypes, rebleeding time and arterial occlusion, was modified in the B6 background, and suggested that interactions occurred among the A/J QTL. |
T3867 |
4378-4379 |
. |
denotes |
. |
T3866 |
4367-4378 |
NN |
denotes |
aggregation |
T3865 |
4358-4366 |
NN |
denotes |
platelet |
T3864 |
4355-4357 |
CC |
denotes |
or |
T3863 |
4343-4354 |
NN |
denotes |
coagulation |
T3862 |
4340-4342 |
IN |
denotes |
to |
T3861 |
4330-4339 |
JJ |
denotes |
unrelated |
T3734 |
3757-3761 |
DT |
denotes |
this |
T3733 |
3754-3756 |
IN |
denotes |
of |
T3732 |
3804-3812 |
VBN |
denotes |
reported |
T3731 |
3746-3753 |
NNS |
denotes |
studies |
T3730 |
3738-3745 |
JJ |
denotes |
Several |
T3729 |
3737-3994 |
sentence |
denotes |
Several studies of this CSS panel, B6 Chr1-19, X, YA/J, have been reported for behavior [12], weight gain [13], sterols [13], and plasma amino acids levels [13,14], and have identified many more QTL than studies of the same traits using a genome-wide scan. |
T3728 |
3736-3737 |
. |
denotes |
. |
T3727 |
3733-3736 |
NN |
denotes |
QTL |
T3726 |
3730-3732 |
IN |
denotes |
of |
T3725 |
3721-3722 |
HYPH |
denotes |
- |
T3724 |
3717-3721 |
RB |
denotes |
fine |
T3723 |
3722-3729 |
VBG |
denotes |
mapping |
T3722 |
3713-3716 |
DT |
denotes |
the |
T3721 |
3700-3703 |
NN |
denotes |
CSS |
T3720 |
3696-3699 |
DT |
denotes |
the |
T3719 |
3691-3695 |
IN |
denotes |
with |
T3718 |
3683-3690 |
NNS |
denotes |
screens |
T3717 |
3675-3682 |
JJ |
denotes |
initial |
T3716 |
3673-3675 |
, |
denotes |
, |
T3715 |
3665-3673 |
NN |
denotes |
addition |
T3714 |
3704-3712 |
VBP |
denotes |
simplify |
T3713 |
3662-3664 |
IN |
denotes |
In |
T3712 |
3661-3737 |
sentence |
denotes |
In addition, initial screens with the CSS simplify the fine-mapping of QTL. |
T3711 |
3660-3661 |
. |
denotes |
. |
T3710 |
3657-3660 |
NN |
denotes |
QTL |
T3709 |
3651-3656 |
JJ |
denotes |
other |
T3708 |
3648-3650 |
IN |
denotes |
of |
T3707 |
3639-3647 |
NN |
denotes |
presence |
T3706 |
3635-3638 |
DT |
denotes |
the |
T3705 |
3632-3634 |
IN |
denotes |
in |
T3704 |
3628-3631 |
NNS |
denotes |
QTL |
T3703 |
3625-3627 |
IN |
denotes |
of |
T3702 |
3615-3624 |
NN |
denotes |
detection |
T3701 |
3611-3614 |
IN |
denotes |
for |
T3700 |
3603-3610 |
NN |
denotes |
ability |
T3699 |
3599-3602 |
DT |
denotes |
the |
T3698 |
3596-3598 |
VBZ |
denotes |
is |
T3697 |
3586-3595 |
NN |
denotes |
advantage |
T3696 |
3578-3585 |
DT |
denotes |
Another |
T3695 |
3577-3661 |
sentence |
denotes |
Another advantage is the ability for detection of QTL in the presence of other QTL. |
T3694 |
3576-3577 |
. |
denotes |
. |
T3693 |
3566-3567 |
HYPH |
denotes |
- |
T3692 |
3567-3571 |
JJ |
denotes |
wide |
T3691 |
3560-3566 |
NN |
denotes |
genome |
T3690 |
3572-3576 |
NN |
denotes |
scan |
T3689 |
3558-3559 |
DT |
denotes |
a |
T3688 |
3553-3557 |
VBZ |
denotes |
does |
T3687 |
3548-3552 |
IN |
denotes |
than |
T3686 |
3544-3547 |
NN |
denotes |
QTL |
T3685 |
3540-3543 |
DT |
denotes |
the |
T3684 |
3530-3539 |
VB |
denotes |
determine |
T3683 |
3527-3529 |
TO |
denotes |
to |
T3682 |
3522-3526 |
NNS |
denotes |
mice |
T3681 |
3516-3521 |
JJR |
denotes |
fewer |
T3680 |
3501-3506 |
NN |
denotes |
panel |
T3679 |
3496-3500 |
DT |
denotes |
this |
T3678 |
3493-3495 |
IN |
denotes |
of |
T3677 |
3507-3515 |
VBZ |
denotes |
requires |
T3676 |
3489-3492 |
NN |
denotes |
Use |
T3675 |
3488-3577 |
sentence |
denotes |
Use of this panel requires fewer mice to determine the QTL than does a genome-wide scan. |
T3674 |
3487-3488 |
. |
denotes |
. |
T3673 |
3477-3487 |
NN |
denotes |
chromosome |
T3672 |
3472-3476 |
DT |
denotes |
this |
T3671 |
3469-3471 |
IN |
denotes |
on |
T3670 |
3457-3460 |
NN |
denotes |
QTL |
T3669 |
3447-3452 |
RBS |
denotes |
least |
T3668 |
3453-3456 |
CD |
denotes |
one |
T3667 |
3444-3446 |
RB |
denotes |
at |
T3666 |
3461-3468 |
VBZ |
denotes |
resides |
T3665 |
3439-3443 |
IN |
denotes |
that |
T3664 |
3431-3438 |
VBZ |
denotes |
implies |
T3663 |
3427-3430 |
CC |
denotes |
and |
T3662 |
3418-3422 |
JJR |
denotes |
more |
T3661 |
3415-3417 |
CC |
denotes |
or |
T3660 |
3423-3426 |
NN |
denotes |
CSS |
T3659 |
3411-3414 |
CD |
denotes |
one |
T3658 |
3408-3410 |
IN |
denotes |
in |
T3657 |
3402-3407 |
NN |
denotes |
trait |
T3656 |
3400-3401 |
DT |
denotes |
a |
T3655 |
3397-3399 |
IN |
denotes |
of |
T3654 |
3382-3396 |
NN |
denotes |
identification |
T3653 |
3378-3381 |
DT |
denotes |
the |
T3652 |
3371-3377 |
VBZ |
denotes |
allows |
T3651 |
3366-3370 |
DT |
denotes |
This |
T3650 |
3365-3488 |
sentence |
denotes |
This allows the identification of a trait in one or more CSS and implies that at least one QTL resides on this chromosome. |
T3649 |
3364-3365 |
. |
denotes |
. |
T3648 |
3351-3353 |
NN |
denotes |
B6 |
T3647 |
3354-3364 |
NN |
denotes |
background |
T3646 |
3349-3350 |
DT |
denotes |
a |
T3645 |
3346-3348 |
IN |
denotes |
in |
T3644 |
3341-3345 |
NNS |
denotes |
mice |
T3643 |
3338-3339 |
HYPH |
denotes |
/ |
T3642 |
3339-3340 |
NN |
denotes |
J |
T3641 |
3337-3338 |
NN |
denotes |
A |
T3640 |
3332-3336 |
IN |
denotes |
from |
T3639 |
3321-3331 |
NN |
denotes |
chromosome |
T3638 |
3317-3320 |
CD |
denotes |
one |
T3637 |
3312-3316 |
VBP |
denotes |
have |
T3636 |
3304-3311 |
NNS |
denotes |
strains |
T3635 |
3298-3303 |
DT |
denotes |
These |
T3634 |
3297-3365 |
sentence |
denotes |
These strains have one chromosome from A/J mice in a B6 background. |
T3633 |
3296-3297 |
. |
denotes |
. |
T3632 |
3286-3296 |
NN |
denotes |
chromosome |
T3631 |
3283-3284 |
HYPH |
denotes |
/ |
T3630 |
3282-3283 |
NN |
denotes |
A |
T3629 |
3271-3281 |
JJ |
denotes |
individual |
T3628 |
3284-3285 |
NN |
denotes |
J |
T3627 |
3267-3270 |
DT |
denotes |
the |
T3626 |
3263-3266 |
CC |
denotes |
and |
T3625 |
3261-3262 |
-RRB- |
denotes |
) |
T3624 |
3258-3259 |
-LRB- |
denotes |
( |
T3623 |
3247-3257 |
NN |
denotes |
background |
T3622 |
3259-3261 |
NN |
denotes |
B6 |
T3621 |
3243-3246 |
DT |
denotes |
the |
T3620 |
3240-3242 |
IN |
denotes |
in |
T3619 |
3227-3239 |
NN |
denotes |
homozygosity |
T3618 |
3218-3226 |
VB |
denotes |
identify |
T3617 |
3215-3217 |
TO |
denotes |
to |
T3616 |
3205-3209 |
VBD |
denotes |
were |
T3860 |
4328-4330 |
, |
denotes |
, |
T3859 |
4304-4317 |
JJ |
denotes |
prothrombotic |
T3858 |
4318-4328 |
NNS |
denotes |
phenotypes |
T3857 |
4296-4303 |
JJ |
denotes |
diverse |
T3856 |
4289-4291 |
, |
denotes |
, |
T3855 |
4282-4283 |
HYPH |
denotes |
/ |
T3854 |
4283-4284 |
NN |
denotes |
J |
T3853 |
4281-4282 |
NN |
denotes |
A |
T3852 |
4277-4280 |
CC |
denotes |
and |
T3851 |
4285-4289 |
NNS |
denotes |
mice |
T3850 |
4274-4276 |
NN |
denotes |
B6 |
T3849 |
4272-4274 |
, |
denotes |
, |
T3848 |
4258-4264 |
JJ |
denotes |
inbred |
T3847 |
4254-4257 |
CD |
denotes |
two |
T3846 |
4265-4272 |
NNS |
denotes |
strains |
T3845 |
4250-4253 |
DT |
denotes |
the |
T3844 |
4291-4295 |
VBP |
denotes |
have |
T3843 |
4245-4249 |
IN |
denotes |
that |
T3842 |
4230-4235 |
NN |
denotes |
study |
T3841 |
4225-4229 |
DT |
denotes |
this |
T3840 |
4222-4224 |
IN |
denotes |
of |
T3839 |
4236-4244 |
VBP |
denotes |
indicate |
T3838 |
4214-4221 |
NNS |
denotes |
results |
T3837 |
4210-4213 |
DT |
denotes |
The |
T3836 |
4209-4379 |
sentence |
denotes |
The results of this study indicate that the two inbred strains, B6 and A/J mice, have diverse prothrombotic phenotypes, unrelated to coagulation or platelet aggregation. |
T3835 |
4208-4209 |
. |
denotes |
. |
T3834 |
4196-4208 |
NN |
denotes |
fibrinolysis |
T3833 |
4192-4195 |
CC |
denotes |
and |
T3832 |
4180-4191 |
NN |
denotes |
coagulation |
T3831 |
4177-4179 |
IN |
denotes |
of |
T3830 |
4168-4176 |
NNS |
denotes |
measures |
T3829 |
4164-4167 |
CC |
denotes |
and |
T3828 |
4162-4164 |
, |
denotes |
, |
T3827 |
4157-4162 |
NN |
denotes |
assay |
T3826 |
4148-4156 |
NN |
denotes |
bleeding |
T3825 |
4143-4147 |
NN |
denotes |
tail |
T3824 |
4141-4143 |
, |
denotes |
, |
T3823 |
4129-4135 |
NN |
denotes |
injury |
T3822 |
4120-4128 |
JJ |
denotes |
vascular |
T3821 |
4111-4119 |
NN |
denotes |
chloride |
T3820 |
4104-4110 |
JJ |
denotes |
ferric |
T3819 |
4136-4141 |
NN |
denotes |
model |
T3818 |
4102-4103 |
DT |
denotes |
a |
T3817 |
4092-4101 |
VBG |
denotes |
utilizing |
T3816 |
4090-4092 |
, |
denotes |
, |
T3815 |
4086-4090 |
NN |
denotes |
risk |
T3814 |
4072-4085 |
JJ |
denotes |
prothrombotic |
T3813 |
4068-4071 |
IN |
denotes |
for |
T3812 |
4063-4067 |
NNS |
denotes |
mice |
T3811 |
4060-4062 |
IN |
denotes |
of |
T3810 |
4045-4051 |
JJ |
denotes |
inbred |
T3809 |
4041-4044 |
CD |
denotes |
two |
T3808 |
4052-4059 |
NNS |
denotes |
strains |
T3807 |
4037-4040 |
DT |
denotes |
the |
T3806 |
4028-4036 |
VB |
denotes |
evaluate |
T3805 |
4025-4027 |
TO |
denotes |
to |
T3804 |
4015-4020 |
NN |
denotes |
study |
T3803 |
4010-4014 |
DT |
denotes |
this |
T3802 |
4007-4009 |
IN |
denotes |
of |
T3801 |
4021-4024 |
VBD |
denotes |
was |
T3800 |
3999-4006 |
NN |
denotes |
purpose |
T3799 |
3995-3998 |
DT |
denotes |
The |
T3798 |
3994-4209 |
sentence |
denotes |
The purpose of this study was to evaluate the two inbred strains of mice for prothrombotic risk, utilizing a ferric chloride vascular injury model, tail bleeding assay, and measures of coagulation and fibrinolysis. |
T3797 |
3993-3994 |
. |
denotes |
. |
T3796 |
3983-3984 |
HYPH |
denotes |
- |
T3795 |
3984-3988 |
JJ |
denotes |
wide |
T3794 |
3977-3983 |
NN |
denotes |
genome |
T3793 |
3989-3993 |
NN |
denotes |
scan |
T3792 |
3975-3976 |
DT |
denotes |
a |
T3791 |
3969-3974 |
VBG |
denotes |
using |
T3790 |
3957-3961 |
JJ |
denotes |
same |
T3789 |
3962-3968 |
NNS |
denotes |
traits |
T3788 |
3953-3956 |
DT |
denotes |
the |
T3787 |
3950-3952 |
IN |
denotes |
of |
T3786 |
3942-3949 |
NNS |
denotes |
studies |
T3785 |
3937-3941 |
IN |
denotes |
than |
T3784 |
3933-3936 |
NN |
denotes |
QTL |
T3783 |
3928-3932 |
JJR |
denotes |
more |
T3782 |
3923-3927 |
JJ |
denotes |
many |
T3781 |
3912-3922 |
VBN |
denotes |
identified |
T3780 |
3907-3911 |
VBP |
denotes |
have |
T3779 |
3903-3906 |
CC |
denotes |
and |
T3778 |
3901-3903 |
, |
denotes |
, |
T3777 |
3900-3901 |
-RRB- |
denotes |
] |
T3776 |
3897-3898 |
, |
denotes |
, |
T3775 |
3895-3897 |
CD |
denotes |
13 |
T3774 |
3898-3900 |
CD |
denotes |
14 |
T3773 |
3894-3895 |
-LRB- |
denotes |
[ |
T3772 |
3881-3886 |
NNS |
denotes |
acids |
T3771 |
3875-3880 |
NN |
denotes |
amino |
T3770 |
3887-3893 |
NNS |
denotes |
levels |
T3769 |
3868-3874 |
NN |
denotes |
plasma |
T3768 |
3864-3867 |
CC |
denotes |
and |
T3767 |
3862-3864 |
, |
denotes |
, |
T3766 |
3861-3862 |
-RRB- |
denotes |
] |
T3765 |
3859-3861 |
CD |
denotes |
13 |
T3764 |
3858-3859 |
-LRB- |
denotes |
[ |
T3763 |
3850-3857 |
NNS |
denotes |
sterols |
T3762 |
3848-3850 |
, |
denotes |
, |
T3761 |
3847-3848 |
-RRB- |
denotes |
] |
T3760 |
3845-3847 |
CD |
denotes |
13 |
T3759 |
3844-3845 |
-LRB- |
denotes |
[ |
T3758 |
3839-3843 |
NN |
denotes |
gain |
T3757 |
3832-3838 |
NN |
denotes |
weight |
T3756 |
3830-3832 |
, |
denotes |
, |
T3755 |
3829-3830 |
-RRB- |
denotes |
] |
T3754 |
3827-3829 |
CD |
denotes |
12 |
T3753 |
3826-3827 |
-LRB- |
denotes |
[ |
T3752 |
3817-3825 |
NN |
denotes |
behavior |
T3751 |
3813-3816 |
IN |
denotes |
for |
T3750 |
3799-3803 |
VBN |
denotes |
been |
T3749 |
3794-3798 |
VBP |
denotes |
have |
T3748 |
3792-3794 |
, |
denotes |
, |
T3747 |
3790-3791 |
HYPH |
denotes |
/ |
T3746 |
3791-3792 |
NN |
denotes |
J |
T3745 |
3788-3790 |
NN |
denotes |
YA |
T3744 |
3786-3788 |
, |
denotes |
, |
T3743 |
3785-3786 |
NN |
denotes |
X |
T3742 |
3783-3785 |
, |
denotes |
, |
T3741 |
3780-3781 |
HYPH |
denotes |
- |
T3740 |
3776-3780 |
NN |
denotes |
Chr1 |
T3739 |
3781-3783 |
NN |
denotes |
19 |
T3738 |
3773-3775 |
NN |
denotes |
B6 |
T3737 |
3771-3773 |
, |
denotes |
, |
T3736 |
3762-3765 |
NN |
denotes |
CSS |
T3735 |
3766-3771 |
NN |
denotes |
panel |
T20564 |
2414-2428 |
NN |
denotes |
Identification |
T20565 |
2429-2431 |
IN |
denotes |
of |
T20566 |
2432-2436 |
NNS |
denotes |
mice |
T20567 |
2437-2448 |
JJ |
denotes |
susceptible |
T20568 |
2449-2451 |
CC |
denotes |
or |
T20569 |
2452-2461 |
JJ |
denotes |
resistant |
T20570 |
2462-2464 |
IN |
denotes |
to |
T20571 |
2465-2472 |
NN |
denotes |
obesity |
T20572 |
2472-2474 |
, |
denotes |
, |
T20573 |
2474-2489 |
NN |
denotes |
atherosclerosis |
T20574 |
2489-2491 |
, |
denotes |
, |
T20575 |
2491-2494 |
CC |
denotes |
and |
T20576 |
2495-2503 |
JJ |
denotes |
vascular |
T20577 |
2504-2510 |
NN |
denotes |
injury |
T3465 |
1829-1830 |
: |
denotes |
; |
T3466 |
1831-1832 |
NN |
denotes |
A |
T3615 |
3210-3214 |
VBN |
denotes |
used |
T3614 |
3197-3204 |
NNS |
denotes |
markers |
T3613 |
3189-3196 |
JJ |
denotes |
Genetic |
T3612 |
3188-3297 |
sentence |
denotes |
Genetic markers were used to identify homozygosity in the background (B6) and the individual A/J chromosome. |
T3611 |
3187-3188 |
. |
denotes |
. |
T3610 |
3180-3182 |
NN |
denotes |
B6 |
T3609 |
3183-3187 |
NNS |
denotes |
mice |
T3608 |
3176-3179 |
DT |
denotes |
the |
T3607 |
3173-3175 |
IN |
denotes |
to |
T3606 |
3148-3160 |
RB |
denotes |
successively |
T3605 |
3143-3147 |
VBD |
denotes |
were |
T3604 |
3134-3135 |
HYPH |
denotes |
/ |
T3603 |
3135-3136 |
NN |
denotes |
J |
T3602 |
3133-3134 |
NN |
denotes |
A |
T3601 |
3131-3132 |
SYM |
denotes |
× |
T3600 |
3128-3130 |
NN |
denotes |
B6 |
T3599 |
3137-3142 |
NN |
denotes |
cross |
T3598 |
3126-3127 |
DT |
denotes |
a |
T3597 |
3123-3125 |
IN |
denotes |
of |
T3596 |
3115-3122 |
NN |
denotes |
progeny |
T3595 |
3111-3114 |
DT |
denotes |
the |
T3594 |
3161-3172 |
VBN |
denotes |
backcrossed |
T3593 |
3105-3110 |
WRB |
denotes |
where |
T3592 |
3088-3096 |
NN |
denotes |
breeding |
T3591 |
3086-3087 |
'' |
denotes |
" |
T3590 |
3077-3078 |
HYPH |
denotes |
- |
T3589 |
3078-3086 |
VBN |
denotes |
assisted |
T3588 |
3071-3077 |
NN |
denotes |
marker |
T3587 |
3070-3071 |
`` |
denotes |
" |
T3586 |
3097-3104 |
NN |
denotes |
program |
T3585 |
3068-3069 |
DT |
denotes |
a |
T3584 |
3065-3067 |
IN |
denotes |
by |
T3583 |
3063-3064 |
-RRB- |
denotes |
] |
T3582 |
3061-3063 |
CD |
denotes |
11 |
T3581 |
3060-3061 |
-LRB- |
denotes |
[ |
T3580 |
3046-3049 |
VBD |
denotes |
was |
T3579 |
3044-3045 |
-RRB- |
denotes |
) |
T3578 |
3041-3044 |
NNS |
denotes |
CSS |
T3577 |
3040-3041 |
-LRB- |
denotes |
( |
T3576 |
3019-3031 |
NN |
denotes |
substitution |
T3575 |
3032-3039 |
NNS |
denotes |
strains |
T3574 |
3008-3018 |
NN |
denotes |
chromosome |
T3573 |
3005-3007 |
IN |
denotes |
of |
T3572 |
3050-3059 |
VBN |
denotes |
generated |
T3571 |
2999-3004 |
NN |
denotes |
panel |
T3570 |
2999-3188 |
sentence |
denotes |
panel of chromosome substitution strains (CSS) was generated [11] by a "marker-assisted" breeding program where the progeny of a B6 × A/J cross were successively backcrossed to the B6 mice. |
T3569 |
2997-2998 |
NN |
denotes |
A |
T3568 |
2997-2999 |
sentence |
denotes |
A |
R456 |
T3130 |
T3131 |
compound |
Family,history |
R457 |
T3131 |
T3132 |
nsubj |
history,is |
R458 |
T3133 |
T3134 |
punct |
[,1 |
R459 |
T3134 |
T3131 |
parataxis |
1,history |
R460 |
T3135 |
T3134 |
punct |
],1 |
R461 |
T3136 |
T3137 |
det |
the,factor |
R462 |
T3137 |
T3132 |
attr |
factor,is |
R463 |
T3138 |
T3137 |
amod |
strongest,factor |
R464 |
T3139 |
T3137 |
compound |
risk,factor |
R465 |
T3140 |
T3137 |
prep |
for,factor |
R466 |
T3141 |
T3142 |
amod |
cardiovascular,diseases |
R467 |
T3142 |
T3140 |
pobj |
diseases,for |
R468 |
T3143 |
T3142 |
punct |
(,diseases |
R469 |
T3144 |
T3142 |
appos |
CVD,diseases |
R470 |
T3145 |
T3132 |
punct |
),is |
R471 |
T3146 |
T3132 |
punct |
.,is |
R472 |
T3148 |
T3149 |
mark |
While,identified |
R473 |
T3149 |
T3157 |
advcl |
identified,account |
R474 |
T3150 |
T3151 |
det |
a,number |
R475 |
T3151 |
T3149 |
nsubjpass |
number,identified |
R476 |
T3152 |
T3151 |
prep |
of,number |
R477 |
T3153 |
T3154 |
amod |
genetic,mutations |
R478 |
T3154 |
T3152 |
pobj |
mutations,of |
R479 |
T3155 |
T3149 |
aux |
have,identified |
R480 |
T3156 |
T3149 |
auxpass |
been,identified |
R481 |
T3158 |
T3157 |
punct |
", ",account |
R482 |
T3159 |
T3157 |
nsubj |
these,account |
R483 |
T3160 |
T3157 |
prep |
for,account |
R484 |
T3161 |
T3162 |
advmod |
only,percentage |
R485 |
T3162 |
T3160 |
pobj |
percentage,for |
R486 |
T3163 |
T3162 |
det |
a,percentage |
R487 |
T3164 |
T3162 |
amod |
small,percentage |
R488 |
T3165 |
T3162 |
prep |
of,percentage |
R489 |
T3166 |
T3167 |
det |
the,CVD |
R490 |
T3167 |
T3165 |
pobj |
CVD,of |
R491 |
T3168 |
T3167 |
prep |
in,CVD |
R492 |
T3169 |
T3170 |
amod |
human,populations |
R493 |
T3170 |
T3168 |
pobj |
populations,in |
R494 |
T3171 |
T3157 |
punct |
.,account |
R495 |
T3173 |
T3174 |
compound |
Thrombus,formation |
R496 |
T3174 |
T3175 |
nsubj |
formation,is |
R497 |
T3176 |
T3174 |
prep |
on,formation |
R498 |
T3177 |
T3178 |
amod |
fissured,plaques |
R500 |
T3179 |
T3178 |
amod |
atherosclerotic,plaques |
R501 |
T3180 |
T3181 |
det |
the,event |
R503 |
T3182 |
T3181 |
amod |
precipitating,event |
R504 |
T3183 |
T3181 |
prep |
in,event |
R505 |
T3184 |
T3185 |
det |
the,transition |
R506 |
T3185 |
T3183 |
pobj |
transition,in |
R507 |
T3186 |
T3185 |
prep |
from,transition |
R508 |
T3187 |
T3188 |
det |
a,disease |
R509 |
T3188 |
T3186 |
pobj |
disease,from |
R510 |
T3189 |
T3188 |
amod |
stable,disease |
R511 |
T3190 |
T3189 |
cc |
or,stable |
R512 |
T3191 |
T3189 |
conj |
subclinical,stable |
R513 |
T3192 |
T3188 |
amod |
atherosclerotic,disease |
R514 |
T3193 |
T3175 |
cc |
and,is |
R515 |
T3194 |
T3175 |
conj |
leads,is |
R516 |
T3195 |
T3194 |
prep |
to,leads |
R517 |
T3196 |
T3197 |
amod |
acute,infarction |
R519 |
T3198 |
T3197 |
amod |
myocardial,infarction |
R520 |
T3199 |
T3197 |
punct |
", ",infarction |
R521 |
T3200 |
T3201 |
amod |
ischemic,stroke |
R522 |
T3201 |
T3197 |
conj |
stroke,infarction |
R523 |
T3202 |
T3201 |
cc |
or,stroke |
R524 |
T3203 |
T3204 |
amod |
peripheral,arterial |
R525 |
T3204 |
T3205 |
amod |
arterial,occlusion |
R526 |
T3205 |
T3201 |
conj |
occlusion,stroke |
R527 |
T3206 |
T3175 |
punct |
.,is |
R528 |
T3208 |
T3209 |
amod |
Arterial,thrombosis |
R529 |
T3209 |
T3212 |
nsubj |
thrombosis,are |
R530 |
T3210 |
T3208 |
cc |
and,Arterial |
R531 |
T3211 |
T3208 |
conj |
venous,Arterial |
R532 |
T3213 |
T3214 |
amod |
complex,responses |
R533 |
T3214 |
T3212 |
attr |
responses,are |
R534 |
T3215 |
T3212 |
cc |
and,are |
R535 |
T3216 |
T3217 |
auxpass |
are,influenced |
R536 |
T3217 |
T3212 |
conj |
influenced,are |
R537 |
T3218 |
T3217 |
agent |
by,influenced |
R538 |
T3219 |
T3220 |
amod |
multiple,factors |
R539 |
T3220 |
T3218 |
pobj |
factors,by |
R540 |
T3221 |
T3220 |
amod |
genetic,factors |
R541 |
T3222 |
T3221 |
cc |
and,genetic |
R542 |
T3223 |
T3221 |
conj |
environmental,genetic |
R543 |
T3224 |
T3225 |
punct |
[,2 |
R544 |
T3225 |
T3217 |
parataxis |
2,influenced |
R545 |
T3226 |
T3227 |
punct |
-,5 |
R546 |
T3227 |
T3225 |
prep |
5,2 |
R547 |
T3228 |
T3225 |
punct |
],2 |
R548 |
T3229 |
T3212 |
punct |
.,are |
R549 |
T3231 |
T3232 |
nsubjpass |
Polymorphisms,implicated |
R550 |
T3233 |
T3231 |
cc |
and,Polymorphisms |
R551 |
T3234 |
T3231 |
conj |
mutations,Polymorphisms |
R552 |
T3235 |
T3231 |
prep |
in,Polymorphisms |
R553 |
T3236 |
T3237 |
compound |
coagulation,factors |
R554 |
T3237 |
T3235 |
pobj |
factors,in |
R555 |
T3238 |
T3237 |
punct |
", ",factors |
R556 |
T3239 |
T3240 |
amod |
fibrinolytic,factors |
R557 |
T3240 |
T3237 |
conj |
factors,factors |
R558 |
T3241 |
T3240 |
punct |
", ",factors |
R559 |
T3242 |
T3243 |
compound |
platelet,surface |
R560 |
T3243 |
T3244 |
compound |
surface,receptors |
R561 |
T3244 |
T3240 |
conj |
receptors,factors |
R562 |
T3245 |
T3244 |
punct |
", ",receptors |
R563 |
T3246 |
T3247 |
compound |
methylenetetrahydrofalate,reductase |
R564 |
T3247 |
T3244 |
conj |
reductase,receptors |
R565 |
T3248 |
T3247 |
punct |
", ",reductase |
R566 |
T3249 |
T3250 |
amod |
endothelial,synthase |
R567 |
T3250 |
T3247 |
conj |
synthase,reductase |
R568 |
T3251 |
T3252 |
amod |
nitric,oxide |
R569 |
T3252 |
T3250 |
compound |
oxide,synthase |
R570 |
T3253 |
T3250 |
punct |
", ",synthase |
R571 |
T3254 |
T3250 |
cc |
and,synthase |
R572 |
T3255 |
T3256 |
amod |
antioxidant,enzymes |
R573 |
T3256 |
T3250 |
conj |
enzymes,synthase |
R574 |
T3257 |
T3232 |
aux |
have,implicated |
R575 |
T3258 |
T3232 |
auxpass |
been,implicated |
R576 |
T3259 |
T3232 |
prep |
as,implicated |
R577 |
T3260 |
T3261 |
amod |
genetic,determinants |
R578 |
T3261 |
T3259 |
pobj |
determinants,as |
R579 |
T3262 |
T3261 |
prep |
of,determinants |
R580 |
T3263 |
T3262 |
pobj |
susceptibility,of |
R581 |
T3264 |
T3263 |
prep |
to,susceptibility |
R582 |
T3265 |
T3264 |
pobj |
thrombosis,to |
R583 |
T3266 |
T3267 |
punct |
[,7 |
R584 |
T3267 |
T3232 |
parataxis |
7,implicated |
R585 |
T3268 |
T3267 |
nummod |
6,7 |
R586 |
T3269 |
T3267 |
punct |
",",7 |
R587 |
T3270 |
T3267 |
punct |
],7 |
R588 |
T3271 |
T3232 |
punct |
.,implicated |
R589 |
T3273 |
T3274 |
amod |
Great,strides |
R590 |
T3274 |
T3275 |
nsubjpass |
strides,made |
R591 |
T3276 |
T3275 |
aux |
have,made |
R592 |
T3277 |
T3275 |
auxpass |
been,made |
R593 |
T3278 |
T3275 |
prep |
in,made |
R594 |
T3279 |
T3280 |
det |
the,diagnosis |
R595 |
T3280 |
T3278 |
pobj |
diagnosis,in |
R596 |
T3281 |
T3280 |
cc |
and,diagnosis |
R597 |
T3282 |
T3280 |
conj |
treatment,diagnosis |
R598 |
T3283 |
T3280 |
prep |
of,diagnosis |
R599 |
T3284 |
T3283 |
pobj |
thrombosis,of |
R600 |
T3285 |
T3275 |
prep |
in,made |
R601 |
T3286 |
T3287 |
det |
the,decade |
R603 |
T3288 |
T3287 |
amod |
last,decade |
R604 |
T3289 |
T3275 |
punct |
.,made |
R605 |
T3291 |
T3292 |
advmod |
However,lagged |
R606 |
T3293 |
T3292 |
punct |
", ",lagged |
R607 |
T3294 |
T3292 |
nsubj |
strategies,lagged |
R608 |
T3295 |
T3296 |
aux |
to,prevent |
R609 |
T3296 |
T3294 |
advcl |
prevent,strategies |
R610 |
T3297 |
T3296 |
dobj |
thrombosis,prevent |
R611 |
T3298 |
T3292 |
aux |
have,lagged |
R612 |
T3299 |
T3300 |
advmod |
far,behind |
R613 |
T3300 |
T3292 |
advmod |
behind,lagged |
R614 |
T3301 |
T3292 |
prep |
due,lagged |
R615 |
T3302 |
T3301 |
punct |
", ",due |
R616 |
T3303 |
T3301 |
prep |
in,due |
R617 |
T3304 |
T3303 |
amod |
part,in |
R618 |
T3305 |
T3301 |
punct |
", ",due |
R619 |
T3306 |
T3301 |
pcomp |
to,due |
R620 |
T3307 |
T3308 |
det |
the,contribution |
R621 |
T3308 |
T3301 |
pobj |
contribution,due |
R622 |
T3309 |
T3308 |
prep |
of,contribution |
R623 |
T3310 |
T3311 |
amod |
multiple,factors |
R624 |
T3311 |
T3309 |
pobj |
factors,of |
R625 |
T3312 |
T3310 |
punct |
", ",multiple |
R626 |
T3313 |
T3310 |
cc |
and,multiple |
R627 |
T3314 |
T3315 |
advmod |
as,yet |
R628 |
T3315 |
T3316 |
advmod |
yet,undefined |
R629 |
T3316 |
T3310 |
conj |
undefined,multiple |
R630 |
T3317 |
T3311 |
punct |
", ",factors |
R631 |
T3318 |
T3311 |
amod |
genetic,factors |
R632 |
T3319 |
T3320 |
dep |
that,lead |
R633 |
T3320 |
T3311 |
relcl |
lead,factors |
R634 |
T3321 |
T3320 |
prep |
to,lead |
R635 |
T3322 |
T3323 |
amod |
thrombotic,risk |
R636 |
T3323 |
T3321 |
pobj |
risk,to |
R637 |
T3324 |
T3292 |
punct |
.,lagged |
R638 |
T3326 |
T3327 |
advmod |
Moreover,remains |
R639 |
T3328 |
T3327 |
punct |
", ",remains |
R640 |
T3329 |
T3327 |
nsubj |
it,remains |
R641 |
T3330 |
T3327 |
oprd |
unclear,remains |
R642 |
T3331 |
T3332 |
advmod |
how,influences |
R643 |
T3332 |
T3327 |
ccomp |
influences,remains |
R644 |
T3333 |
T3334 |
amod |
genetic,background |
R645 |
T3334 |
T3332 |
nsubj |
background,influences |
R646 |
T3335 |
T3336 |
det |
the,function |
R647 |
T3336 |
T3332 |
dobj |
function,influences |
R648 |
T3337 |
T3336 |
prep |
of,function |
R649 |
T3338 |
T3337 |
pobj |
molecules,of |
R650 |
T3339 |
T3338 |
cc |
and,molecules |
R651 |
T3340 |
T3338 |
conj |
pathways,molecules |
R652 |
T3341 |
T3338 |
acl |
known,molecules |
R653 |
T3342 |
T3343 |
aux |
to,regulate |
R654 |
T3343 |
T3341 |
xcomp |
regulate,known |
R655 |
T3344 |
T3345 |
compound |
thrombus,formation |
R656 |
T3345 |
T3343 |
dobj |
formation,regulate |
R657 |
T3346 |
T3345 |
cc |
and,formation |
R658 |
T3347 |
T3345 |
conj |
lysis,formation |
R659 |
T3348 |
T3332 |
cc |
and,influences |
R660 |
T3349 |
T3332 |
punct |
", ",influences |
R661 |
T3350 |
T3351 |
advmod |
thereby,contributes |
R663 |
T3352 |
T3351 |
punct |
", ",contributes |
R664 |
T3353 |
T3351 |
prep |
to,contributes |
R665 |
T3354 |
T3355 |
det |
the,risk |
R666 |
T3355 |
T3353 |
pobj |
risk,to |
R667 |
T3356 |
T3355 |
prep |
of,risk |
R668 |
T3357 |
T3358 |
amod |
thrombotic,disease |
R669 |
T3358 |
T3356 |
pobj |
disease,of |
R670 |
T3359 |
T3327 |
punct |
.,remains |
R671 |
T3465 |
T3462 |
punct |
;,10 |
R672 |
T3466 |
T3467 |
compound |
A,J |
R673 |
T3467 |
T3469 |
nsubj |
J,susceptible |
R674 |
T3468 |
T3467 |
punct |
/,J |
R675 |
T3469 |
T3462 |
amod |
susceptible,10 |
R676 |
T3470 |
T3462 |
punct |
),10 |
R677 |
T3471 |
T3462 |
punct |
[,10 |
R678 |
T3472 |
T3462 |
punct |
],10 |
R679 |
T3473 |
T3402 |
punct |
.,have |
R680 |
T3475 |
T3476 |
det |
These,conditions |
R681 |
T3476 |
T3477 |
nsubj |
conditions,are |
R682 |
T3478 |
T3477 |
acomp |
predisposing,are |
R683 |
T3479 |
T3478 |
prep |
to,predisposing |
R684 |
T3480 |
T3479 |
pobj |
thrombosis,to |
R685 |
T3481 |
T3482 |
advmod |
per,se |
R686 |
T3361 |
T3362 |
nsubjpass |
Many,classified |
R687 |
T3482 |
T3477 |
advmod |
se,are |
R688 |
T3483 |
T3477 |
punct |
", ",are |
R689 |
T3363 |
T3361 |
prep |
of,Many |
R690 |
T3484 |
T3477 |
cc |
but,are |
R691 |
T3364 |
T3365 |
det |
the,strains |
R692 |
T3365 |
T3363 |
pobj |
strains,of |
R693 |
T3366 |
T3365 |
amod |
available,strains |
R694 |
T3485 |
T3486 |
det |
these,mice |
R695 |
T3367 |
T3368 |
amod |
inbred,mouse |
R696 |
T3368 |
T3365 |
compound |
mouse,strains |
R697 |
T3486 |
T3487 |
nsubjpass |
mice,evaluated |
R698 |
T3369 |
T3365 |
punct |
", ",strains |
R699 |
T3370 |
T3371 |
amod |
such,as |
R700 |
T3371 |
T3365 |
prep |
as,strains |
R701 |
T3487 |
T3477 |
conj |
evaluated,are |
R702 |
T3372 |
T3373 |
compound |
C57BL,6J |
R703 |
T3373 |
T3371 |
pobj |
6J,as |
R704 |
T3374 |
T3373 |
punct |
/,6J |
R705 |
T3488 |
T3487 |
aux |
have,evaluated |
R706 |
T3375 |
T3373 |
punct |
(,6J |
R707 |
T3376 |
T3373 |
appos |
B6,6J |
R708 |
T3377 |
T3373 |
punct |
),6J |
R709 |
T3489 |
T3487 |
neg |
not,evaluated |
R710 |
T3378 |
T3373 |
cc |
and,6J |
R711 |
T3379 |
T3380 |
compound |
A,J |
R712 |
T3380 |
T3373 |
conj |
J,6J |
R713 |
T3490 |
T3487 |
auxpass |
been,evaluated |
R714 |
T3381 |
T3380 |
punct |
/,J |
R715 |
T3382 |
T3362 |
punct |
", ",classified |
R716 |
T3383 |
T3362 |
aux |
have,classified |
R717 |
T3384 |
T3362 |
auxpass |
been,classified |
R718 |
T3385 |
T3362 |
prep |
as,classified |
R719 |
T3386 |
T3385 |
amod |
resistant,as |
R720 |
T3491 |
T3487 |
advmod |
systematically,evaluated |
R721 |
T3387 |
T3386 |
cc |
or,resistant |
R722 |
T3388 |
T3386 |
conj |
susceptible,resistant |
R723 |
T3389 |
T3388 |
prep |
to,susceptible |
R724 |
T3492 |
T3487 |
prep |
for,evaluated |
R725 |
T3390 |
T3391 |
amod |
particular,diseases |
R726 |
T3391 |
T3389 |
pobj |
diseases,to |
R727 |
T3493 |
T3492 |
pobj |
thrombosis,for |
R728 |
T3392 |
T3391 |
amod |
complex,diseases |
R729 |
T3393 |
T3394 |
punct |
(,Table |
R730 |
T3394 |
T3362 |
parataxis |
Table,classified |
R731 |
T3494 |
T3487 |
punct |
.,evaluated |
R732 |
T3395 |
T3394 |
nummod |
1,Table |
R733 |
T3396 |
T3394 |
punct |
),Table |
R734 |
T3397 |
T3362 |
punct |
.,classified |
R735 |
T3496 |
T3497 |
compound |
Clot,formation |
R736 |
T3399 |
T3400 |
det |
These,strains |
R737 |
T3400 |
T3402 |
nsubj |
strains,have |
R738 |
T3401 |
T3400 |
nummod |
two,strains |
R739 |
T3497 |
T3498 |
nsubj |
formation,requires |
R740 |
T3403 |
T3404 |
amod |
diverse,responses |
R741 |
T3404 |
T3402 |
dobj |
responses,have |
R742 |
T3405 |
T3404 |
prep |
to,responses |
R743 |
T3499 |
T3497 |
cc |
and,formation |
R744 |
T3406 |
T3407 |
npadvmod |
diet,induced |
R745 |
T3407 |
T3409 |
amod |
induced,obesity |
R746 |
T3408 |
T3407 |
punct |
-,induced |
R747 |
T3409 |
T3405 |
pobj |
obesity,to |
R748 |
T3500 |
T3497 |
conj |
lysis,formation |
R749 |
T3410 |
T3411 |
punct |
[,8 |
R750 |
T3411 |
T3409 |
parataxis |
8,obesity |
R751 |
T3412 |
T3411 |
punct |
],8 |
R752 |
T3501 |
T3497 |
punct |
", ",formation |
R753 |
T3413 |
T3414 |
punct |
(,resistant |
R754 |
T3414 |
T3409 |
parataxis |
resistant,obesity |
R755 |
T3415 |
T3416 |
nsubj |
B6,susceptible |
R756 |
T3502 |
T3503 |
dep |
which,determine |
R757 |
T3416 |
T3414 |
amod |
susceptible,resistant |
R758 |
T3417 |
T3414 |
punct |
;,resistant |
R759 |
T3418 |
T3419 |
compound |
A,J |
R760 |
T3503 |
T3497 |
relcl |
determine,formation |
R761 |
T3419 |
T3414 |
nsubj |
J,resistant |
R762 |
T3420 |
T3419 |
punct |
/,J |
R763 |
T3421 |
T3414 |
punct |
),resistant |
R764 |
T3504 |
T3503 |
advmod |
ultimately,determine |
R765 |
T3422 |
T3409 |
punct |
", ",obesity |
R766 |
T3423 |
T3424 |
npadvmod |
diet,induced |
R767 |
T3424 |
T3426 |
amod |
induced,atherosclerosis |
R768 |
T3425 |
T3424 |
punct |
-,induced |
R769 |
T3505 |
T3503 |
dobj |
thrombosis,determine |
R770 |
T3506 |
T3498 |
punct |
", ",requires |
R771 |
T3426 |
T3409 |
conj |
atherosclerosis,obesity |
R772 |
T3427 |
T3428 |
punct |
(,resistant |
R773 |
T3507 |
T3508 |
compound |
platelet,aggregation |
R774 |
T3428 |
T3426 |
parataxis |
resistant,atherosclerosis |
R775 |
T3429 |
T3430 |
nsubj |
B6,susceptible |
R776 |
T3508 |
T3498 |
dobj |
aggregation,requires |
R777 |
T3430 |
T3428 |
amod |
susceptible,resistant |
R778 |
T3431 |
T3428 |
punct |
;,resistant |
R779 |
T3432 |
T3433 |
compound |
A,J |
R780 |
T3509 |
T3508 |
punct |
", ",aggregation |
R781 |
T3433 |
T3428 |
nsubj |
J,resistant |
R782 |
T3434 |
T3433 |
punct |
/,J |
R783 |
T3510 |
T3508 |
conj |
coagulation,aggregation |
R784 |
T3435 |
T3428 |
punct |
),resistant |
R785 |
T3436 |
T3437 |
punct |
[,9 |
R787 |
T3437 |
T3426 |
parataxis |
9,atherosclerosis |
R788 |
T3438 |
T3437 |
punct |
],9 |
R789 |
T3439 |
T3426 |
punct |
", ",atherosclerosis |
R791 |
T3440 |
T3441 |
amod |
arterial,ligation |
R792 |
T3441 |
T3442 |
npadvmod |
ligation,induced |
R793 |
T3442 |
T3444 |
amod |
induced,hyperplasia |
R794 |
T3443 |
T3442 |
punct |
-,induced |
R796 |
T3444 |
T3426 |
conj |
hyperplasia,atherosclerosis |
R797 |
T3445 |
T3444 |
amod |
neointimal,hyperplasia |
R799 |
T3446 |
T3447 |
punct |
(,resistant |
R800 |
T3447 |
T3444 |
parataxis |
resistant,hyperplasia |
R801 |
T3448 |
T3449 |
nsubj |
B6,resistant |
R803 |
T3449 |
T3447 |
amod |
resistant,resistant |
R804 |
T3450 |
T3447 |
punct |
;,resistant |
R806 |
T3451 |
T3452 |
compound |
A,J |
R807 |
T3452 |
T3447 |
nsubj |
J,resistant |
R808 |
T3453 |
T3452 |
punct |
/,J |
R809 |
T3454 |
T3447 |
punct |
),resistant |
R810 |
T3455 |
T3444 |
punct |
", ",hyperplasia |
R812 |
T3456 |
T3444 |
cc |
and,hyperplasia |
R813 |
T3457 |
T3458 |
npadvmod |
ligation,induced |
R814 |
T3458 |
T3459 |
amod |
induced,remodeling |
R815 |
T3459 |
T3444 |
conj |
remodeling,hyperplasia |
R817 |
T3460 |
T3459 |
compound |
vessel,remodeling |
R818 |
T3461 |
T3462 |
punct |
(,10 |
R820 |
T3462 |
T3459 |
parataxis |
10,remodeling |
R821 |
T3463 |
T3464 |
nsubj |
B6,resistant |
R822 |
T3464 |
T3462 |
amod |
resistant,10 |
R854 |
T3592 |
T3586 |
compound |
breeding,program |
R855 |
T3593 |
T3594 |
advmod |
where,backcrossed |
R856 |
T3594 |
T3586 |
relcl |
backcrossed,program |
R858 |
T3595 |
T3596 |
det |
the,progeny |
R859 |
T3596 |
T3594 |
nsubjpass |
progeny,backcrossed |
R860 |
T3597 |
T3596 |
prep |
of,progeny |
R861 |
T3598 |
T3599 |
det |
a,cross |
R863 |
T3599 |
T3597 |
pobj |
cross,of |
R864 |
T3600 |
T3599 |
nmod |
B6,cross |
R866 |
T3601 |
T3600 |
punct |
×,B6 |
R867 |
T3602 |
T3603 |
compound |
A,J |
R868 |
T3603 |
T3600 |
appos |
J,B6 |
R869 |
T3604 |
T3603 |
punct |
/,J |
R871 |
T3605 |
T3594 |
auxpass |
were,backcrossed |
R872 |
T3606 |
T3594 |
advmod |
successively,backcrossed |
R873 |
T3607 |
T3594 |
prep |
to,backcrossed |
R874 |
T3608 |
T3609 |
det |
the,mice |
R875 |
T3609 |
T3607 |
pobj |
mice,to |
R876 |
T3610 |
T3609 |
compound |
B6,mice |
R878 |
T3611 |
T3572 |
punct |
.,generated |
R879 |
T3613 |
T3614 |
amod |
Genetic,markers |
R881 |
T3614 |
T3615 |
nsubjpass |
markers,used |
R883 |
T3616 |
T3615 |
auxpass |
were,used |
R884 |
T3617 |
T3618 |
aux |
to,identify |
R885 |
T3618 |
T3615 |
advcl |
identify,used |
R886 |
T3619 |
T3618 |
dobj |
homozygosity,identify |
R888 |
T3620 |
T3619 |
prep |
in,homozygosity |
R889 |
T3621 |
T3622 |
det |
the,B6 |
R890 |
T3543 |
T3533 |
auxpass |
be,identified |
R891 |
T3544 |
T3533 |
prep |
by,identified |
R892 |
T3545 |
T3544 |
pcomp |
associating,by |
R893 |
T3546 |
T3547 |
det |
the,phenotype |
R894 |
T3622 |
T3620 |
pobj |
B6,in |
R895 |
T3623 |
T3622 |
nmod |
background,B6 |
R896 |
T3624 |
T3622 |
punct |
(,B6 |
R897 |
T3547 |
T3545 |
dobj |
phenotype,associating |
R898 |
T3625 |
T3622 |
punct |
),B6 |
R899 |
T3626 |
T3622 |
cc |
and,B6 |
R900 |
T3548 |
T3545 |
prep |
with,associating |
R901 |
T3627 |
T3628 |
det |
the,J |
R902 |
T3628 |
T3632 |
compound |
J,chromosome |
R903 |
T3629 |
T3628 |
amod |
individual,J |
R904 |
T3549 |
T3550 |
det |
a,location |
R905 |
T3630 |
T3628 |
compound |
A,J |
R906 |
T3631 |
T3628 |
punct |
/,J |
R907 |
T3632 |
T3622 |
conj |
chromosome,B6 |
R908 |
T3550 |
T3548 |
pobj |
location,with |
R909 |
T3633 |
T3615 |
punct |
.,used |
R910 |
T3551 |
T3550 |
punct |
(,location |
R911 |
T3552 |
T3550 |
nmod |
s,location |
R912 |
T3635 |
T3636 |
det |
These,strains |
R913 |
T3553 |
T3550 |
punct |
),location |
R914 |
T3636 |
T3637 |
nsubj |
strains,have |
R915 |
T3554 |
T3550 |
prep |
on,location |
R916 |
T3638 |
T3639 |
nummod |
one,chromosome |
R917 |
T3639 |
T3637 |
dobj |
chromosome,have |
R918 |
T3640 |
T3639 |
prep |
from,chromosome |
R919 |
T3555 |
T3556 |
det |
a,chromosome |
R920 |
T3641 |
T3642 |
compound |
A,J |
R921 |
T3642 |
T3644 |
compound |
J,mice |
R922 |
T3643 |
T3642 |
punct |
/,J |
R923 |
T3556 |
T3554 |
pobj |
chromosome,on |
R924 |
T3644 |
T3640 |
pobj |
mice,from |
R925 |
T3645 |
T3637 |
prep |
in,have |
R926 |
T3646 |
T3647 |
det |
a,background |
R927 |
T3647 |
T3645 |
pobj |
background,in |
R928 |
T3648 |
T3647 |
compound |
B6,background |
R929 |
T3557 |
T3556 |
amod |
specific,chromosome |
R930 |
T3649 |
T3637 |
punct |
.,have |
R931 |
T3651 |
T3652 |
nsubj |
This,allows |
R932 |
T3558 |
T3550 |
punct |
", ",location |
R933 |
T3653 |
T3654 |
det |
the,identification |
R934 |
T3654 |
T3652 |
dobj |
identification,allows |
R935 |
T3559 |
T3560 |
det |
a,locus |
R936 |
T3655 |
T3654 |
prep |
of,identification |
R937 |
T3656 |
T3657 |
det |
a,trait |
R938 |
T3657 |
T3655 |
pobj |
trait,of |
R939 |
T3560 |
T3550 |
appos |
locus,location |
R940 |
T3658 |
T3657 |
prep |
in,trait |
R941 |
T3659 |
T3660 |
nummod |
one,CSS |
R942 |
T3561 |
T3560 |
amod |
quantitative,locus |
R943 |
T3660 |
T3658 |
pobj |
CSS,in |
R944 |
T3661 |
T3659 |
cc |
or,one |
R945 |
T3662 |
T3659 |
conj |
more,one |
R946 |
T3562 |
T3560 |
compound |
trait,locus |
R947 |
T3663 |
T3652 |
cc |
and,allows |
R948 |
T3664 |
T3652 |
conj |
implies,allows |
R949 |
T3563 |
T3560 |
punct |
(,locus |
R950 |
T3665 |
T3666 |
mark |
that,resides |
R951 |
T3666 |
T3664 |
ccomp |
resides,implies |
R952 |
T3667 |
T3668 |
advmod |
at,one |
R953 |
T3564 |
T3560 |
appos |
QTL,locus |
R954 |
T3668 |
T3670 |
nummod |
one,QTL |
R955 |
T3669 |
T3668 |
advmod |
least,one |
R956 |
T3670 |
T3666 |
nsubj |
QTL,resides |
R957 |
T3565 |
T3533 |
punct |
),identified |
R958 |
T3671 |
T3666 |
prep |
on,resides |
R959 |
T3672 |
T3673 |
det |
this,chromosome |
R960 |
T3673 |
T3671 |
pobj |
chromosome,on |
R961 |
T3566 |
T3533 |
punct |
.,identified |
R962 |
T3674 |
T3652 |
punct |
.,allows |
R963 |
T3676 |
T3677 |
nsubj |
Use,requires |
R964 |
T3728 |
T3714 |
punct |
.,simplify |
R965 |
T3678 |
T3676 |
prep |
of,Use |
R966 |
T3679 |
T3680 |
det |
this,panel |
R967 |
T3680 |
T3678 |
pobj |
panel,of |
R968 |
T3730 |
T3731 |
amod |
Several,studies |
R969 |
T3681 |
T3682 |
amod |
fewer,mice |
R970 |
T3682 |
T3677 |
dobj |
mice,requires |
R971 |
T3683 |
T3684 |
aux |
to,determine |
R972 |
T3684 |
T3677 |
advcl |
determine,requires |
R973 |
T3685 |
T3686 |
det |
the,QTL |
R974 |
T3731 |
T3732 |
nsubjpass |
studies,reported |
R975 |
T3686 |
T3684 |
dobj |
QTL,determine |
R976 |
T3687 |
T3688 |
mark |
than,does |
R977 |
T3688 |
T3677 |
advcl |
does,requires |
R978 |
T3689 |
T3690 |
det |
a,scan |
R979 |
T3690 |
T3688 |
nsubj |
scan,does |
R980 |
T3691 |
T3692 |
npadvmod |
genome,wide |
R981 |
T3692 |
T3690 |
amod |
wide,scan |
R982 |
T3733 |
T3731 |
prep |
of,studies |
R983 |
T3693 |
T3692 |
punct |
-,wide |
R984 |
T3694 |
T3677 |
punct |
.,requires |
R985 |
T3696 |
T3697 |
det |
Another,advantage |
R986 |
T3734 |
T3735 |
det |
this,panel |
R987 |
T3697 |
T3698 |
nsubj |
advantage,is |
R988 |
T3699 |
T3700 |
det |
the,ability |
R989 |
T3735 |
T3733 |
pobj |
panel,of |
R990 |
T3700 |
T3698 |
attr |
ability,is |
R991 |
T3701 |
T3700 |
prep |
for,ability |
R992 |
T3702 |
T3701 |
pobj |
detection,for |
R993 |
T3703 |
T3702 |
prep |
of,detection |
R994 |
T3736 |
T3735 |
compound |
CSS,panel |
R995 |
T3704 |
T3703 |
pobj |
QTL,of |
R996 |
T3705 |
T3702 |
prep |
in,detection |
R997 |
T3706 |
T3707 |
det |
the,presence |
R998 |
T3737 |
T3735 |
punct |
", ",panel |
R999 |
T3707 |
T3705 |
pobj |
presence,in |
R1000 |
T3708 |
T3707 |
prep |
of,presence |
R1001 |
T3709 |
T3710 |
amod |
other,QTL |
R1002 |
T3738 |
T3739 |
compound |
B6,19 |
R1003 |
T3710 |
T3708 |
pobj |
QTL,of |
R1004 |
T3711 |
T3698 |
punct |
.,is |
R1005 |
T3739 |
T3735 |
appos |
19,panel |
R1006 |
T3713 |
T3714 |
prep |
In,simplify |
R1007 |
T3740 |
T3739 |
compound |
Chr1,19 |
R1008 |
T3715 |
T3713 |
pobj |
addition,In |
R1009 |
T3716 |
T3714 |
punct |
", ",simplify |
R1010 |
T3717 |
T3718 |
amod |
initial,screens |
R1011 |
T3718 |
T3714 |
nsubj |
screens,simplify |
R1012 |
T3741 |
T3739 |
punct |
-,19 |
R1013 |
T3719 |
T3718 |
prep |
with,screens |
R1014 |
T3720 |
T3721 |
det |
the,CSS |
R1015 |
T3742 |
T3739 |
punct |
", ",19 |
R1016 |
T3721 |
T3719 |
pobj |
CSS,with |
R1017 |
T3722 |
T3723 |
det |
the,mapping |
R1018 |
T3743 |
T3739 |
appos |
X,19 |
R1019 |
T3723 |
T3714 |
dobj |
mapping,simplify |
R1020 |
T3744 |
T3739 |
punct |
", ",19 |
R1021 |
T3724 |
T3723 |
advmod |
fine,mapping |
R1022 |
T3725 |
T3723 |
punct |
-,mapping |
R1023 |
T3745 |
T3746 |
compound |
YA,J |
R1024 |
T3726 |
T3723 |
prep |
of,mapping |
R1025 |
T3727 |
T3726 |
pobj |
QTL,of |
R1026 |
T3746 |
T3739 |
appos |
J,19 |
R1027 |
T3747 |
T3746 |
punct |
/,J |
R1028 |
T3748 |
T3732 |
punct |
", ",reported |
R1029 |
T3834 |
T3832 |
conj |
fibrinolysis,coagulation |
R1030 |
T3749 |
T3732 |
aux |
have,reported |
R1031 |
T3835 |
T3801 |
punct |
.,was |
R1032 |
T3750 |
T3732 |
auxpass |
been,reported |
R1033 |
T3837 |
T3838 |
det |
The,results |
R1034 |
T3838 |
T3839 |
nsubj |
results,indicate |
R1035 |
T3751 |
T3732 |
prep |
for,reported |
R1036 |
T3840 |
T3838 |
prep |
of,results |
R1037 |
T3841 |
T3842 |
det |
this,study |
R1038 |
T3752 |
T3751 |
pobj |
behavior,for |
R1039 |
T3842 |
T3840 |
pobj |
study,of |
R1040 |
T3843 |
T3844 |
mark |
that,have |
R1041 |
T3844 |
T3839 |
ccomp |
have,indicate |
R1042 |
T3753 |
T3754 |
punct |
[,12 |
R1043 |
T3845 |
T3846 |
det |
the,strains |
R1044 |
T3846 |
T3844 |
nsubj |
strains,have |
R1045 |
T3754 |
T3752 |
parataxis |
12,behavior |
R1046 |
T3847 |
T3846 |
nummod |
two,strains |
R1047 |
T3848 |
T3846 |
amod |
inbred,strains |
R1048 |
T3849 |
T3846 |
punct |
", ",strains |
R1049 |
T3755 |
T3754 |
punct |
],12 |
R1050 |
T3850 |
T3851 |
nmod |
B6,mice |
R1051 |
T3851 |
T3846 |
appos |
mice,strains |
R1052 |
T3852 |
T3850 |
cc |
and,B6 |
R1053 |
T3756 |
T3752 |
punct |
", ",behavior |
R1054 |
T3853 |
T3854 |
compound |
A,J |
R1055 |
T3854 |
T3850 |
conj |
J,B6 |
R1056 |
T3757 |
T3758 |
compound |
weight,gain |
R1057 |
T3855 |
T3854 |
punct |
/,J |
R1058 |
T3758 |
T3752 |
conj |
gain,behavior |
R1059 |
T3856 |
T3844 |
punct |
", ",have |
R1060 |
T3857 |
T3858 |
amod |
diverse,phenotypes |
R1061 |
T3858 |
T3844 |
dobj |
phenotypes,have |
R1062 |
T3859 |
T3858 |
amod |
prothrombotic,phenotypes |
R1063 |
T3759 |
T3760 |
punct |
[,13 |
R1064 |
T3860 |
T3858 |
punct |
", ",phenotypes |
R1065 |
T3861 |
T3858 |
amod |
unrelated,phenotypes |
R1066 |
T3760 |
T3758 |
parataxis |
13,gain |
R1067 |
T3862 |
T3861 |
prep |
to,unrelated |
R1068 |
T3863 |
T3862 |
pobj |
coagulation,to |
R1069 |
T3864 |
T3863 |
cc |
or,coagulation |
R1070 |
T3761 |
T3760 |
punct |
],13 |
R1071 |
T3865 |
T3866 |
compound |
platelet,aggregation |
R1072 |
T3866 |
T3863 |
conj |
aggregation,coagulation |
R1073 |
T3867 |
T3839 |
punct |
.,indicate |
R1074 |
T3762 |
T3758 |
punct |
", ",gain |
R1075 |
T3869 |
T3870 |
prep |
In,modified |
R1076 |
T3763 |
T3758 |
conj |
sterols,gain |
R1077 |
T3871 |
T3869 |
pobj |
addition,In |
R1078 |
T3872 |
T3870 |
punct |
", ",modified |
R1079 |
T3764 |
T3765 |
punct |
[,13 |
R1080 |
T3873 |
T3870 |
prep |
in,modified |
R1081 |
T3874 |
T3875 |
det |
the,CSS |
R1082 |
T3875 |
T3873 |
pobj |
CSS,in |
R1083 |
T3876 |
T3870 |
punct |
", ",modified |
R1084 |
T3877 |
T3870 |
nsubjpass |
expression,modified |
R1085 |
T3878 |
T3877 |
prep |
of,expression |
R1086 |
T3765 |
T3763 |
parataxis |
13,sterols |
R1087 |
T3879 |
T3880 |
det |
the,phenotypes |
R1088 |
T3880 |
T3878 |
pobj |
phenotypes,of |
R1089 |
T3881 |
T3882 |
compound |
A,J |
R1090 |
T3766 |
T3765 |
punct |
],13 |
R1091 |
T3882 |
T3880 |
compound |
J,phenotypes |
R1092 |
T3883 |
T3882 |
punct |
/,J |
R1093 |
T3767 |
T3763 |
punct |
", ",sterols |
R1094 |
T3884 |
T3880 |
punct |
", ",phenotypes |
R1095 |
T3885 |
T3886 |
compound |
rebleeding,time |
R1096 |
T3886 |
T3880 |
conj |
time,phenotypes |
R1097 |
T3887 |
T3886 |
cc |
and,time |
R1098 |
T3768 |
T3763 |
cc |
and,sterols |
R1099 |
T3888 |
T3889 |
amod |
arterial,occlusion |
R1100 |
T3889 |
T3886 |
conj |
occlusion,time |
R1101 |
T3769 |
T3770 |
compound |
plasma,levels |
R1102 |
T3890 |
T3870 |
punct |
", ",modified |
R1103 |
T3891 |
T3870 |
auxpass |
was,modified |
R1104 |
T3892 |
T3870 |
prep |
in,modified |
R1105 |
T3770 |
T3763 |
conj |
levels,sterols |
R1106 |
T3771 |
T3772 |
compound |
amino,acids |
R1107 |
T3893 |
T3894 |
det |
the,background |
R1108 |
T3772 |
T3770 |
compound |
acids,levels |
R1109 |
T3894 |
T3892 |
pobj |
background,in |
R1110 |
T3895 |
T3894 |
compound |
B6,background |
R1111 |
T3773 |
T3774 |
punct |
[,14 |
R1112 |
T3896 |
T3870 |
punct |
", ",modified |
R1113 |
T3897 |
T3870 |
cc |
and,modified |
R1114 |
T3774 |
T3770 |
parataxis |
14,levels |
R1115 |
T3898 |
T3870 |
conj |
suggested,modified |
R1116 |
T3899 |
T3900 |
mark |
that,occurred |
R1117 |
T3900 |
T3898 |
ccomp |
occurred,suggested |
R1118 |
T3775 |
T3774 |
nummod |
13,14 |
R1119 |
T3901 |
T3900 |
nsubj |
interactions,occurred |
R1120 |
T3902 |
T3900 |
prep |
among,occurred |
R1121 |
T3776 |
T3774 |
punct |
",",14 |
R1122 |
T3903 |
T3904 |
det |
the,QTL |
R1123 |
T3904 |
T3902 |
pobj |
QTL,among |
R1124 |
T3905 |
T3906 |
compound |
A,J |
R1125 |
T3777 |
T3774 |
punct |
],14 |
R1126 |
T3906 |
T3904 |
compound |
J,QTL |
R1127 |
T3907 |
T3906 |
punct |
/,J |
R1128 |
T3778 |
T3732 |
punct |
", ",reported |
R1129 |
T3908 |
T3870 |
punct |
.,modified |
R1130 |
T3910 |
T3911 |
advmod |
Thus,be |
R1131 |
T3779 |
T3732 |
cc |
and,reported |
R1132 |
T3912 |
T3911 |
punct |
", ",be |
R1133 |
T3913 |
T3911 |
nsubj |
it,be |
R1134 |
T3914 |
T3911 |
aux |
should,be |
R1135 |
T3915 |
T3911 |
acomp |
possible,be |
R1136 |
T3780 |
T3781 |
aux |
have,identified |
R1137 |
T3916 |
T3917 |
aux |
to,identify |
R1138 |
T3917 |
T3911 |
xcomp |
identify,be |
R1139 |
T3918 |
T3919 |
amod |
independent,determinants |
R1140 |
T3919 |
T3917 |
dobj |
determinants,identify |
R1141 |
T3781 |
T3732 |
conj |
identified,reported |
R1142 |
T3920 |
T3919 |
amod |
genetic,determinants |
R1143 |
T3921 |
T3919 |
prep |
of,determinants |
R1144 |
T3922 |
T3921 |
pobj |
susceptibility,of |
R1145 |
T3782 |
T3783 |
amod |
many,more |
R1146 |
T3923 |
T3922 |
prep |
to,susceptibility |
R1147 |
T3924 |
T3925 |
amod |
pathological,haemostasis |
R1148 |
T3783 |
T3784 |
amod |
more,QTL |
R1149 |
T3925 |
T3923 |
pobj |
haemostasis,to |
R1150 |
T3926 |
T3925 |
cc |
and,haemostasis |
R1151 |
T3927 |
T3925 |
conj |
thrombosis,haemostasis |
R1152 |
T3784 |
T3781 |
dobj |
QTL,identified |
R1153 |
T3928 |
T3911 |
punct |
.,be |
R1154 |
T3785 |
T3784 |
prep |
than,QTL |
R1155 |
T3786 |
T3785 |
pobj |
studies,than |
R1156 |
T3787 |
T3786 |
prep |
of,studies |
R1157 |
T3788 |
T3789 |
det |
the,traits |
R1158 |
T3789 |
T3787 |
pobj |
traits,of |
R1159 |
T3790 |
T3789 |
amod |
same,traits |
R1160 |
T3791 |
T3786 |
acl |
using,studies |
R1161 |
T3792 |
T3793 |
det |
a,scan |
R1162 |
T3793 |
T3791 |
dobj |
scan,using |
R1163 |
T3794 |
T3795 |
npadvmod |
genome,wide |
R1164 |
T3795 |
T3793 |
amod |
wide,scan |
R1165 |
T3796 |
T3795 |
punct |
-,wide |
R1166 |
T3797 |
T3732 |
punct |
.,reported |
R1167 |
T3799 |
T3800 |
det |
The,purpose |
R1168 |
T3800 |
T3801 |
nsubj |
purpose,was |
R1169 |
T3802 |
T3800 |
prep |
of,purpose |
R1170 |
T3803 |
T3804 |
det |
this,study |
R1171 |
T3804 |
T3802 |
pobj |
study,of |
R1172 |
T3805 |
T3806 |
aux |
to,evaluate |
R1173 |
T3806 |
T3801 |
xcomp |
evaluate,was |
R1174 |
T3807 |
T3808 |
det |
the,strains |
R1175 |
T3808 |
T3806 |
dobj |
strains,evaluate |
R1176 |
T3809 |
T3808 |
nummod |
two,strains |
R1177 |
T3810 |
T3808 |
amod |
inbred,strains |
R1178 |
T3811 |
T3808 |
prep |
of,strains |
R1179 |
T3812 |
T3811 |
pobj |
mice,of |
R1180 |
T3813 |
T3806 |
prep |
for,evaluate |
R1181 |
T3814 |
T3815 |
amod |
prothrombotic,risk |
R1182 |
T3815 |
T3813 |
pobj |
risk,for |
R1183 |
T3816 |
T3806 |
punct |
", ",evaluate |
R1184 |
T3817 |
T3806 |
advcl |
utilizing,evaluate |
R1185 |
T3818 |
T3819 |
det |
a,model |
R1186 |
T3819 |
T3817 |
dobj |
model,utilizing |
R1187 |
T3820 |
T3821 |
amod |
ferric,chloride |
R1188 |
T3821 |
T3819 |
nmod |
chloride,model |
R1189 |
T3822 |
T3823 |
amod |
vascular,injury |
R1190 |
T3823 |
T3819 |
compound |
injury,model |
R1191 |
T3824 |
T3819 |
punct |
", ",model |
R1192 |
T3825 |
T3826 |
compound |
tail,bleeding |
R1193 |
T3826 |
T3827 |
compound |
bleeding,assay |
R1194 |
T3827 |
T3819 |
conj |
assay,model |
R1195 |
T3828 |
T3827 |
punct |
", ",assay |
R1196 |
T3829 |
T3827 |
cc |
and,assay |
R1197 |
T3830 |
T3827 |
conj |
measures,assay |
R1198 |
T3831 |
T3830 |
prep |
of,measures |
R1199 |
T3832 |
T3831 |
pobj |
coagulation,of |
R1200 |
T3833 |
T3832 |
cc |
and,coagulation |
R6393 |
T20565 |
T20564 |
prep |
of,Identification |
R6394 |
T20566 |
T20565 |
pobj |
mice,of |
R6395 |
T20567 |
T20566 |
amod |
susceptible,mice |
R6396 |
T20568 |
T20567 |
cc |
or,susceptible |
R6397 |
T20569 |
T20567 |
conj |
resistant,susceptible |
R6398 |
T20570 |
T20569 |
prep |
to,resistant |
R6399 |
T20571 |
T20570 |
pobj |
obesity,to |
R6400 |
T20572 |
T20571 |
punct |
", ",obesity |
R6401 |
T20573 |
T20571 |
conj |
atherosclerosis,obesity |
R6402 |
T20574 |
T20573 |
punct |
", ",atherosclerosis |
R6403 |
T20575 |
T20573 |
cc |
and,atherosclerosis |
R6404 |
T20576 |
T20577 |
amod |
vascular,injury |
R6405 |
T20577 |
T20573 |
conj |
injury,atherosclerosis |
R499 |
T3178 |
T3176 |
pobj |
plaques,on |
R502 |
T3181 |
T3175 |
attr |
event,is |
R518 |
T3197 |
T3195 |
pobj |
infarction,to |
R602 |
T3287 |
T3285 |
pobj |
decade,in |
R662 |
T3351 |
T3332 |
conj |
contributes,influences |
R786 |
T3511 |
T3510 |
punct |
", ",coagulation |
R790 |
T3512 |
T3510 |
cc |
and,coagulation |
R795 |
T3513 |
T3514 |
amod |
fibrinolytic,functions |
R798 |
T3514 |
T3510 |
conj |
functions,coagulation |
R802 |
T3515 |
T3498 |
punct |
.,requires |
R805 |
T3517 |
T3518 |
nsubj |
Interactions,occur |
R811 |
T3519 |
T3517 |
prep |
among,Interactions |
R816 |
T3520 |
T3521 |
det |
these,pathways |
R819 |
T3521 |
T3519 |
pobj |
pathways,among |
R823 |
T3522 |
T3518 |
aux |
may,occur |
R824 |
T3523 |
T3518 |
cc |
and,occur |
R825 |
T3524 |
T3525 |
amod |
additional,factors |
R827 |
T3525 |
T3526 |
nsubj |
factors,modulate |
R830 |
T3526 |
T3518 |
conj |
modulate,occur |
R833 |
T3527 |
T3526 |
aux |
may,modulate |
R836 |
T3528 |
T3529 |
det |
these,processes |
R840 |
T3529 |
T3526 |
dobj |
processes,modulate |
R844 |
T3530 |
T3526 |
punct |
.,modulate |
R848 |
T3532 |
T3533 |
nsubjpass |
Identification,identified |
R853 |
T3534 |
T3532 |
prep |
of,Identification |
R857 |
T3535 |
T3536 |
amod |
novel,modulators |
R862 |
T3536 |
T3534 |
pobj |
modulators,of |
R865 |
T3537 |
T3536 |
cc |
and,modulators |
R870 |
T3538 |
T3536 |
conj |
factors,modulators |
R877 |
T3539 |
T3536 |
prep |
of,modulators |
R880 |
T3540 |
T3541 |
det |
these,pathways |
R882 |
T3541 |
T3539 |
pobj |
pathways,of |
R887 |
T3542 |
T3533 |
aux |
can,identified |
R826 |
T3571 |
T3572 |
nsubjpass |
panel,generated |
R828 |
T3573 |
T3571 |
prep |
of,panel |
R829 |
T3574 |
T3575 |
compound |
chromosome,strains |
R831 |
T3575 |
T3573 |
pobj |
strains,of |
R832 |
T3576 |
T3575 |
compound |
substitution,strains |
R834 |
T3577 |
T3575 |
punct |
(,strains |
R835 |
T3578 |
T3575 |
appos |
CSS,strains |
R837 |
T3579 |
T3572 |
punct |
),generated |
R838 |
T3580 |
T3572 |
auxpass |
was,generated |
R839 |
T3581 |
T3582 |
punct |
[,11 |
R841 |
T3582 |
T3572 |
parataxis |
11,generated |
R842 |
T3583 |
T3582 |
punct |
],11 |
R843 |
T3584 |
T3572 |
agent |
by,generated |
R845 |
T3585 |
T3586 |
det |
a,program |
R846 |
T3586 |
T3584 |
pobj |
program,by |
R847 |
T3587 |
T3586 |
punct |
"""",program |
R849 |
T3588 |
T3589 |
npadvmod |
marker,assisted |
R850 |
T3589 |
T3586 |
amod |
assisted,program |
R851 |
T3590 |
T3589 |
punct |
-,assisted |
R852 |
T3591 |
T3586 |
punct |
"""",program |