PMC:1617083 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1008	8-18	NN	denotes	background
T1009	0-67	sentence	denotes	Genetic background determines response to hemostasis and thrombosis
T1010	19-29	VBZ	denotes	determines
T1011	30-38	NN	denotes	response
T1012	39-41	IN	denotes	to
T1013	42-52	NN	denotes	hemostasis
T1014	53-56	CC	denotes	and
T1015	57-67	NN	denotes	thrombosis
T1016	67-68	sentence	denotes
T1017	78-88	sentence	denotes	Background
T1018	78-88	NN	denotes	Background
T1019	88-233	sentence	denotes	Thrombosis is the fatal and disabling consequence of cardiovascular diseases, the leading cause of mortality and morbidity in Western countries.
T1020	89-99	NN	denotes	Thrombosis
T1021	100-102	VBZ	denotes	is
T1022	103-106	DT	denotes	the
T1023	127-138	NN	denotes	consequence
T1024	107-112	JJ	denotes	fatal
T1025	113-116	CC	denotes	and
T1026	117-126	VBG	denotes	disabling
T1027	139-141	IN	denotes	of
T1028	142-156	JJ	denotes	cardiovascular
T1029	157-165	NNS	denotes	diseases
T1030	165-167	,	denotes	,
T1031	167-170	DT	denotes	the
T1032	179-184	NN	denotes	cause
T1033	171-178	VBG	denotes	leading
T1034	185-187	IN	denotes	of
T1035	188-197	NN	denotes	mortality
T1036	198-201	CC	denotes	and
T1037	202-211	NN	denotes	morbidity
T1038	212-214	IN	denotes	in
T1039	215-222	JJ	denotes	Western
T1040	223-232	NNS	denotes	countries
T1041	232-233	.	denotes	.
T1042	233-371	sentence	denotes	Two inbred mouse strains, C57BL/6J and A/J, have marked differences in susceptibility to obesity, atherosclerosis, and vessel remodeling.
T1043	234-237	CD	denotes	Two
T1044	251-258	NNS	denotes	strains
T1045	238-244	JJ	denotes	inbred
T1046	245-250	NN	denotes	mouse
T1047	278-282	VBP	denotes	have
T1048	258-260	,	denotes	,
T1049	260-265	NN	denotes	C57BL
T1050	266-268	NN	denotes	6J
T1051	265-266	HYPH	denotes	/
T1052	269-272	CC	denotes	and
T1053	273-274	NN	denotes	A
T1054	275-276	NN	denotes	J
T1055	274-275	HYPH	denotes	/
T1056	276-278	,	denotes	,
T1057	283-289	JJ	denotes	marked
T1058	290-301	NNS	denotes	differences
T1059	302-304	IN	denotes	in
T1060	305-319	NN	denotes	susceptibility
T1061	320-322	IN	denotes	to
T1062	323-330	NN	denotes	obesity
T1063	330-332	,	denotes	,
T1064	332-347	NN	denotes	atherosclerosis
T1065	347-349	,	denotes	,
T1066	349-352	CC	denotes	and
T1067	353-359	NN	denotes	vessel
T1068	360-370	NN	denotes	remodeling
T1069	370-371	.	denotes	.
T1070	371-496	sentence	denotes	However, it is unclear how these diverse genetic backgrounds influence pathways known to regulate thrombosis and hemostasis.
T1071	372-379	RB	denotes	However
T1072	384-386	VBZ	denotes	is
T1073	379-381	,	denotes	,
T1074	381-383	PRP	denotes	it
T1075	387-394	JJ	denotes	unclear
T1076	395-398	WRB	denotes	how
T1077	433-442	VBP	denotes	influence
T1078	399-404	DT	denotes	these
T1079	421-432	NNS	denotes	backgrounds
T1080	405-412	JJ	denotes	diverse
T1081	413-420	JJ	denotes	genetic
T1082	443-451	NNS	denotes	pathways
T1083	452-457	VBN	denotes	known
T1084	458-460	TO	denotes	to
T1085	461-469	VB	denotes	regulate
T1086	470-480	NN	denotes	thrombosis
T1087	481-484	CC	denotes	and
T1088	485-495	NN	denotes	hemostasis
T1089	495-496	.	denotes	.
T1090	496-679	sentence	denotes	The objective of this study was to evaluate thrombosis and hemostasis in these two inbred strains and determine the phenotypic response of A/J chromosomes in the C57BL/6J background.
T1091	497-500	DT	denotes	The
T1092	501-510	NN	denotes	objective
T1093	525-528	VBD	denotes	was
T1094	511-513	IN	denotes	of
T1095	514-518	DT	denotes	this
T1096	519-524	NN	denotes	study
T1097	529-531	TO	denotes	to
T1098	532-540	VB	denotes	evaluate
T1099	541-551	NN	denotes	thrombosis
T1100	552-555	CC	denotes	and
T1101	556-566	NN	denotes	hemostasis
T1102	567-569	IN	denotes	in
T1103	570-575	DT	denotes	these
T1104	587-594	NNS	denotes	strains
T1105	576-579	CD	denotes	two
T1106	580-586	JJ	denotes	inbred
T1107	595-598	CC	denotes	and
T1108	599-608	VB	denotes	determine
T1109	609-612	DT	denotes	the
T1110	624-632	NN	denotes	response
T1111	613-623	JJ	denotes	phenotypic
T1112	633-635	IN	denotes	of
T1113	636-637	NN	denotes	A
T1114	638-639	NN	denotes	J
T1115	637-638	HYPH	denotes	/
T1116	640-651	NNS	denotes	chromosomes
T1117	652-654	IN	denotes	in
T1118	655-658	DT	denotes	the
T1119	668-678	NN	denotes	background
T1120	659-664	NN	denotes	C57BL
T1121	665-667	NN	denotes	6J
T1122	664-665	HYPH	denotes	/
T1123	678-679	.	denotes	.
T1124	679-688	sentence	denotes	Methods
T1125	681-688	NNS	denotes	Methods
T1126	688-771	sentence	denotes	A/J and C57Bl/6J mice were evaluated for differences in thrombosis and hemostasis.
T1127	689-690	NN	denotes	A
T1128	691-692	NN	denotes	J
T1129	690-691	HYPH	denotes	/
T1130	706-710	NNS	denotes	mice
T1131	693-696	CC	denotes	and
T1132	697-702	NN	denotes	C57Bl
T1133	703-705	NN	denotes	6J
T1134	702-703	HYPH	denotes	/
T1135	716-725	VBN	denotes	evaluated
T1136	711-715	VBD	denotes	were
T1137	726-729	IN	denotes	for
T1138	730-741	NNS	denotes	differences
T1139	742-744	IN	denotes	in
T1140	745-755	NN	denotes	thrombosis
T1141	756-759	CC	denotes	and
T1142	760-770	NN	denotes	hemostasis
T1143	770-771	.	denotes	.
T1144	771-924	sentence	denotes	A thrombus was induced in the carotid artery by application of the exposed carotid to ferric chloride and blood flow measured until the vessel occluded.
T1145	772-773	DT	denotes	A
T1146	774-782	NN	denotes	thrombus
T1147	787-794	VBN	denotes	induced
T1148	783-786	VBD	denotes	was
T1149	795-797	IN	denotes	in
T1150	798-801	DT	denotes	the
T1151	810-816	NN	denotes	artery
T1152	802-809	JJ	denotes	carotid
T1153	817-819	IN	denotes	by
T1154	820-831	NN	denotes	application
T1155	832-834	IN	denotes	of
T1156	835-838	DT	denotes	the
T1157	847-854	NN	denotes	carotid
T1158	839-846	VBN	denotes	exposed
T1159	855-857	IN	denotes	to
T1160	858-864	JJ	denotes	ferric
T1161	865-873	NN	denotes	chloride
T1162	874-877	CC	denotes	and
T1163	878-883	NN	denotes	blood
T1164	884-888	NN	denotes	flow
T1165	889-897	VBN	denotes	measured
T1166	898-903	IN	denotes	until
T1167	915-923	VBD	denotes	occluded
T1168	904-907	DT	denotes	the
T1169	908-914	NN	denotes	vessel
T1170	923-924	.	denotes	.
T1171	924-1075	sentence	denotes	Bleeding and rebleeding times, as surrogate markers for thrombosis and hemostasis, were determined after clipping the tail and placing in warm saline.
T1172	925-933	NN	denotes	Bleeding
T1173	949-954	NNS	denotes	times
T1174	934-937	CC	denotes	and
T1175	938-948	NN	denotes	rebleeding
T1176	1013-1023	VBN	denotes	determined
T1177	954-956	,	denotes	,
T1178	956-958	IN	denotes	as
T1179	959-968	JJ	denotes	surrogate
T1180	969-976	NNS	denotes	markers
T1181	977-980	IN	denotes	for
T1182	981-991	NN	denotes	thrombosis
T1183	992-995	CC	denotes	and
T1184	996-1006	NN	denotes	hemostasis
T1185	1006-1008	,	denotes	,
T1186	1008-1012	VBD	denotes	were
T1187	1024-1029	IN	denotes	after
T1188	1030-1038	VBG	denotes	clipping
T1189	1039-1042	DT	denotes	the
T1190	1043-1047	NN	denotes	tail
T1191	1048-1051	CC	denotes	and
T1192	1052-1059	VBG	denotes	placing
T1193	1060-1062	IN	denotes	in
T1194	1063-1067	JJ	denotes	warm
T1195	1068-1074	NN	denotes	saline
T1196	1074-1075	.	denotes	.
T1197	1075-1216	sentence	denotes	Twenty-one chromosome substitution strains, A/J chromosomes in a C57BL/6J background, were screened for response to the tail bleeding assay.
T1198	1076-1082	CD	denotes	Twenty
T1199	1083-1086	CD	denotes	one
T1200	1082-1083	HYPH	denotes	-
T1201	1111-1118	NNS	denotes	strains
T1202	1087-1097	NN	denotes	chromosome
T1203	1098-1110	NN	denotes	substitution
T1204	1167-1175	VBN	denotes	screened
T1205	1118-1120	,	denotes	,
T1206	1120-1121	NN	denotes	A
T1207	1122-1123	NN	denotes	J
T1208	1121-1122	HYPH	denotes	/
T1209	1124-1135	NNS	denotes	chromosomes
T1210	1136-1138	IN	denotes	in
T1211	1139-1140	DT	denotes	a
T1212	1150-1160	NN	denotes	background
T1213	1141-1146	NN	denotes	C57BL
T1214	1147-1149	NN	denotes	6J
T1215	1146-1147	HYPH	denotes	/
T1216	1160-1162	,	denotes	,
T1217	1162-1166	VBD	denotes	were
T1218	1176-1179	IN	denotes	for
T1219	1180-1188	NN	denotes	response
T1220	1189-1191	IN	denotes	to
T1221	1192-1195	DT	denotes	the
T1222	1210-1215	NN	denotes	assay
T1223	1196-1200	NN	denotes	tail
T1224	1201-1209	NN	denotes	bleeding
T1225	1215-1216	.	denotes	.
T1226	1216-1225	sentence	denotes	Results
T1227	1218-1225	NNS	denotes	Results
T1228	1225-1315	sentence	denotes	Thrombus occlusion time was markedly decreased in the A/J mice compared to C57BL/6J mice.
T1229	1226-1234	NN	denotes	Thrombus
T1230	1235-1244	NN	denotes	occlusion
T1231	1245-1249	NN	denotes	time
T1232	1263-1272	VBN	denotes	decreased
T1233	1250-1253	VBD	denotes	was
T1234	1254-1262	RB	denotes	markedly
T1235	1273-1275	IN	denotes	in
T1236	1276-1279	DT	denotes	the
T1237	1284-1288	NNS	denotes	mice
T1238	1280-1281	NN	denotes	A
T1239	1282-1283	NN	denotes	J
T1240	1281-1282	HYPH	denotes	/
T1241	1289-1297	VBN	denotes	compared
T1242	1298-1300	IN	denotes	to
T1243	1301-1306	NN	denotes	C57BL
T1244	1307-1309	NN	denotes	6J
T1245	1306-1307	HYPH	denotes	/
T1246	1310-1314	NNS	denotes	mice
T1247	1314-1315	.	denotes	.
T1248	1315-1452	sentence	denotes	Tail bleeding time was similar in the two strains, but rebleeding time was markedly increased in the A/J mice compared to C57BL/6J mice.
T1249	1316-1320	NN	denotes	Tail
T1250	1321-1329	NN	denotes	bleeding
T1251	1330-1334	NN	denotes	time
T1252	1335-1338	VBD	denotes	was
T1253	1339-1346	JJ	denotes	similar
T1254	1347-1349	IN	denotes	in
T1255	1350-1353	DT	denotes	the
T1256	1358-1365	NNS	denotes	strains
T1257	1354-1357	CD	denotes	two
T1258	1365-1367	,	denotes	,
T1259	1367-1370	CC	denotes	but
T1260	1371-1381	NN	denotes	rebleeding
T1261	1382-1386	NN	denotes	time
T1262	1400-1409	VBN	denotes	increased
T1263	1387-1390	VBD	denotes	was
T1264	1391-1399	RB	denotes	markedly
T1265	1410-1412	IN	denotes	in
T1266	1413-1416	DT	denotes	the
T1267	1421-1425	NNS	denotes	mice
T1268	1417-1418	NN	denotes	A
T1269	1419-1420	NN	denotes	J
T1270	1418-1419	HYPH	denotes	/
T1271	1426-1434	VBN	denotes	compared
T1272	1435-1437	IN	denotes	to
T1273	1438-1443	NN	denotes	C57BL
T1274	1444-1446	NN	denotes	6J
T1275	1443-1444	HYPH	denotes	/
T1276	1447-1451	NNS	denotes	mice
T1277	1451-1452	.	denotes	.
T1278	1452-1568	sentence	denotes	Coagulation times and tail morphology were similar, but tail collagen content was higher in A/J than C57BL/6J mice.
T1279	1453-1464	NN	denotes	Coagulation
T1280	1465-1470	NNS	denotes	times
T1281	1491-1495	VBD	denotes	were
T1282	1471-1474	CC	denotes	and
T1283	1475-1479	NN	denotes	tail
T1284	1480-1490	NN	denotes	morphology
T1285	1496-1503	JJ	denotes	similar
T1286	1503-1505	,	denotes	,
T1287	1505-1508	CC	denotes	but
T1288	1509-1513	NN	denotes	tail
T1289	1514-1522	NN	denotes	collagen
T1290	1523-1530	NN	denotes	content
T1291	1531-1534	VBD	denotes	was
T1292	1535-1541	JJR	denotes	higher
T1293	1542-1544	IN	denotes	in
T1294	1545-1546	NN	denotes	A
T1295	1547-1548	NN	denotes	J
T1296	1546-1547	HYPH	denotes	/
T1297	1549-1553	IN	denotes	than
T1298	1554-1559	NN	denotes	C57BL
T1299	1560-1562	NN	denotes	6J
T1300	1559-1560	HYPH	denotes	/
T1301	1563-1567	NNS	denotes	mice
T1302	1567-1568	.	denotes	.
T1303	1568-1730	sentence	denotes	Three chromosome substitution strains, B6-Chr5A/J, B6-Chr11A/J, and B6-Chr17A/J, were identified with increased rebleeding time, a phenotype similar to A/J mice.
T1304	1569-1574	CD	denotes	Three
T1305	1599-1606	NNS	denotes	strains
T1306	1575-1585	NN	denotes	chromosome
T1307	1586-1598	NN	denotes	substitution
T1308	1655-1665	VBN	denotes	identified
T1309	1606-1608	,	denotes	,
T1310	1608-1610	NN	denotes	B6
T1311	1611-1616	NN	denotes	Chr5A
T1312	1610-1611	HYPH	denotes	-
T1313	1617-1618	NN	denotes	J
T1314	1616-1617	HYPH	denotes	/
T1315	1618-1620	,	denotes	,
T1316	1620-1622	NN	denotes	B6
T1317	1623-1629	NN	denotes	Chr11A
T1318	1622-1623	HYPH	denotes	-
T1319	1630-1631	NN	denotes	J
T1320	1629-1630	HYPH	denotes	/
T1321	1631-1633	,	denotes	,
T1322	1633-1636	CC	denotes	and
T1323	1637-1639	NN	denotes	B6
T1324	1640-1646	NN	denotes	Chr17A
T1325	1639-1640	HYPH	denotes	-
T1326	1647-1648	NN	denotes	J
T1327	1646-1647	HYPH	denotes	/
T1328	1648-1650	,	denotes	,
T1329	1650-1654	VBD	denotes	were
T1330	1666-1670	IN	denotes	with
T1331	1671-1680	VBN	denotes	increased
T1332	1692-1696	NN	denotes	time
T1333	1681-1691	NN	denotes	rebleeding
T1334	1696-1698	,	denotes	,
T1335	1698-1699	DT	denotes	a
T1336	1700-1709	NN	denotes	phenotype
T1337	1710-1717	JJ	denotes	similar
T1338	1718-1720	IN	denotes	to
T1339	1721-1722	NN	denotes	A
T1340	1723-1724	NN	denotes	J
T1341	1722-1723	HYPH	denotes	/
T1342	1725-1729	NNS	denotes	mice
T1343	1729-1730	.	denotes	.
T1344	1730-1980	sentence	denotes	Mice heterosomic for chromosomes 5 or 17 had rebleeding times similar to C57BL/6J mice, but when these two chromosome substitution strains, B6-Chr5A/J and B6-Chr17A/J, were crossed, the A/J phenotype was restored in these doubly heterosomic progeny.
T1345	1731-1735	NNS	denotes	Mice
T1346	1772-1775	VBD	denotes	had
T1347	1736-1747	JJ	denotes	heterosomic
T1348	1748-1751	IN	denotes	for
T1349	1752-1763	NNS	denotes	chromosomes
T1350	1764-1765	CD	denotes	5
T1351	1766-1768	CC	denotes	or
T1352	1769-1771	CD	denotes	17
T1353	1776-1786	NN	denotes	rebleeding
T1354	1787-1792	NNS	denotes	times
T1355	1793-1800	JJ	denotes	similar
T1356	1801-1803	IN	denotes	to
T1357	1804-1809	NN	denotes	C57BL
T1358	1810-1812	NN	denotes	6J
T1359	1809-1810	HYPH	denotes	/
T1360	1813-1817	NNS	denotes	mice
T1361	1817-1819	,	denotes	,
T1362	1819-1822	CC	denotes	but
T1363	1823-1827	IN	denotes	when
T1364	1904-1911	VBN	denotes	crossed
T1365	1828-1833	DT	denotes	these
T1366	1862-1869	NNS	denotes	strains
T1367	1834-1837	CD	denotes	two
T1368	1838-1848	NN	denotes	chromosome
T1369	1849-1861	NN	denotes	substitution
T1370	1869-1871	,	denotes	,
T1371	1871-1873	NN	denotes	B6
T1372	1874-1879	NN	denotes	Chr5A
T1373	1873-1874	HYPH	denotes	-
T1374	1880-1881	NN	denotes	J
T1375	1879-1880	HYPH	denotes	/
T1376	1882-1885	CC	denotes	and
T1377	1886-1888	NN	denotes	B6
T1378	1889-1895	NN	denotes	Chr17A
T1379	1888-1889	HYPH	denotes	-
T1380	1896-1897	NN	denotes	J
T1381	1895-1896	HYPH	denotes	/
T1382	1897-1899	,	denotes	,
T1383	1899-1903	VBD	denotes	were
T1384	1935-1943	VBN	denotes	restored
T1385	1911-1913	,	denotes	,
T1386	1913-1916	DT	denotes	the
T1387	1921-1930	NN	denotes	phenotype
T1388	1917-1918	NN	denotes	A
T1389	1919-1920	NN	denotes	J
T1390	1918-1919	HYPH	denotes	/
T1391	1931-1934	VBD	denotes	was
T1392	1944-1946	IN	denotes	in
T1393	1947-1952	DT	denotes	these
T1394	1972-1979	NN	denotes	progeny
T1395	1953-1959	RB	denotes	doubly
T1396	1960-1971	JJ	denotes	heterosomic
T1397	1979-1980	.	denotes	.
T1398	1980-1992	sentence	denotes	Conclusion
T1399	1982-1992	NN	denotes	Conclusion
T1400	1992-2121	sentence	denotes	These results indicate that susceptibility to arterial thrombosis and haemostasis is remarkably different in C57BL/and A/J mice.
T1401	1993-1998	DT	denotes	These
T1402	1999-2006	NNS	denotes	results
T1403	2007-2015	VBP	denotes	indicate
T1404	2016-2020	IN	denotes	that
T1405	2075-2077	VBZ	denotes	is
T1406	2021-2035	NN	denotes	susceptibility
T1407	2036-2038	IN	denotes	to
T1408	2039-2047	JJ	denotes	arterial
T1409	2048-2058	NN	denotes	thrombosis
T1410	2059-2062	CC	denotes	and
T1411	2063-2074	NN	denotes	haemostasis
T1412	2078-2088	RB	denotes	remarkably
T1413	2089-2098	JJ	denotes	different
T1414	2099-2101	IN	denotes	in
T1415	2102-2107	NN	denotes	C57BL
T1416	2114-2115	NN	denotes	J
T1417	2107-2108	HYPH	denotes	/
T1418	2108-2111	CC	denotes	and
T1419	2112-2113	NN	denotes	A
T1420	2113-2114	HYPH	denotes	/
T1421	2116-2120	NNS	denotes	mice
T1422	2120-2121	.	denotes	.
T1423	2121-2357	sentence	denotes	Three A/J chromosome substitution strains were identified that expressed a phenotype similar to A/J for rebleeding, the C57Bl/6J background could modify the A/J phenotype, and the combination of two A/J QTL could restore the phenotype.
T1424	2122-2127	CD	denotes	Three
T1425	2156-2163	NNS	denotes	strains
T1426	2128-2129	NN	denotes	A
T1427	2130-2131	NN	denotes	J
T1428	2129-2130	HYPH	denotes	/
T1429	2132-2142	NN	denotes	chromosome
T1430	2143-2155	NN	denotes	substitution
T1431	2169-2179	VBN	denotes	identified
T1432	2164-2168	VBD	denotes	were
T1433	2180-2184	WDT	denotes	that
T1434	2185-2194	VBD	denotes	expressed
T1435	2195-2196	DT	denotes	a
T1436	2197-2206	NN	denotes	phenotype
T1437	2207-2214	JJ	denotes	similar
T1438	2215-2217	IN	denotes	to
T1439	2218-2219	NN	denotes	A
T1440	2220-2221	NN	denotes	J
T1441	2219-2220	HYPH	denotes	/
T1442	2222-2225	IN	denotes	for
T1443	2226-2236	VBG	denotes	rebleeding
T1444	2236-2238	,	denotes	,
T1445	2238-2241	DT	denotes	the
T1446	2251-2261	NN	denotes	background
T1447	2242-2247	NN	denotes	C57Bl
T1448	2248-2250	NN	denotes	6J
T1449	2247-2248	HYPH	denotes	/
T1450	2268-2274	VB	denotes	modify
T1451	2262-2267	MD	denotes	could
T1452	2275-2278	DT	denotes	the
T1453	2283-2292	NN	denotes	phenotype
T1454	2279-2280	NN	denotes	A
T1455	2281-2282	NN	denotes	J
T1456	2280-2281	HYPH	denotes	/
T1457	2292-2294	,	denotes	,
T1458	2294-2297	CC	denotes	and
T1459	2298-2301	DT	denotes	the
T1460	2302-2313	NN	denotes	combination
T1461	2335-2342	VB	denotes	restore
T1462	2314-2316	IN	denotes	of
T1463	2317-2320	CD	denotes	two
T1464	2325-2328	NN	denotes	QTL
T1465	2321-2322	NN	denotes	A
T1466	2323-2324	NN	denotes	J
T1467	2322-2323	HYPH	denotes	/
T1468	2329-2334	MD	denotes	could
T1469	2343-2346	DT	denotes	the
T1470	2347-2356	NN	denotes	phenotype
T1471	2356-2357	.	denotes	.
T1472	2357-2569	sentence	denotes	The diverse genetic backgrounds and differences in response to vascular injury induced thrombosis and the tail bleeding assay, suggest the potential for identifying novel genetic determinants of thrombotic risk.
T1473	2358-2361	DT	denotes	The
T1474	2378-2389	NNS	denotes	backgrounds
T1475	2362-2369	JJ	denotes	diverse
T1476	2370-2377	JJ	denotes	genetic
T1477	2485-2492	VBP	denotes	suggest
T1478	2390-2393	CC	denotes	and
T1479	2394-2405	NNS	denotes	differences
T1480	2406-2408	IN	denotes	in
T1481	2409-2417	NN	denotes	response
T1482	2418-2420	IN	denotes	to
T1483	2421-2429	JJ	denotes	vascular
T1484	2430-2436	NN	denotes	injury
T1485	2437-2444	VBN	denotes	induced
T1486	2445-2455	NN	denotes	thrombosis
T1487	2456-2459	CC	denotes	and
T1488	2460-2463	DT	denotes	the
T1489	2478-2483	NN	denotes	assay
T1490	2464-2468	NN	denotes	tail
T1491	2469-2477	NN	denotes	bleeding
T1492	2483-2485	,	denotes	,
T1493	2493-2496	DT	denotes	the
T1494	2497-2506	NN	denotes	potential
T1495	2507-2510	IN	denotes	for
T1496	2511-2522	VBG	denotes	identifying
T1497	2523-2528	JJ	denotes	novel
T1498	2537-2549	NNS	denotes	determinants
T1499	2529-2536	JJ	denotes	genetic
T1500	2550-2552	IN	denotes	of
T1501	2553-2563	JJ	denotes	thrombotic
T1502	2564-2568	NN	denotes	risk
T1503	2568-2569	.	denotes	.
T3130	2582-2588	NN	denotes	Family
T3131	2589-2596	NN	denotes	history
T3132	2601-2603	VBZ	denotes	is
T3133	2597-2598	-LRB-	denotes	[
T3134	2598-2599	CD	denotes	1
T3135	2599-2600	-RRB-	denotes	]
T3136	2604-2607	DT	denotes	the
T3137	2623-2629	NN	denotes	factor
T3138	2608-2617	JJS	denotes	strongest
T3139	2618-2622	NN	denotes	risk
T3140	2630-2633	IN	denotes	for
T3141	2634-2648	JJ	denotes	cardiovascular
T3142	2649-2657	NNS	denotes	diseases
T3143	2658-2659	-LRB-	denotes	(
T3144	2659-2662	NNS	denotes	CVD
T3145	2662-2663	-RRB-	denotes	)
T3146	2663-2664	.	denotes	.
T3147	2664-2797	sentence	denotes	While a number of genetic mutations have been identified, these account for only a small percentage of the CVD in human populations.
T3148	2665-2670	IN	denotes	While
T3149	2711-2721	VBN	denotes	identified
T3150	2671-2672	DT	denotes	a
T3151	2673-2679	NN	denotes	number
T3152	2680-2682	IN	denotes	of
T3153	2683-2690	JJ	denotes	genetic
T3154	2691-2700	NNS	denotes	mutations
T3155	2701-2705	VBP	denotes	have
T3156	2706-2710	VBN	denotes	been
T3157	2729-2736	VBP	denotes	account
T3158	2721-2723	,	denotes	,
T3159	2723-2728	DT	denotes	these
T3160	2737-2740	IN	denotes	for
T3161	2741-2745	RB	denotes	only
T3162	2754-2764	NN	denotes	percentage
T3163	2746-2747	DT	denotes	a
T3164	2748-2753	JJ	denotes	small
T3165	2765-2767	IN	denotes	of
T3166	2768-2771	DT	denotes	the
T3167	2772-2775	NNS	denotes	CVD
T3168	2776-2778	IN	denotes	in
T3169	2779-2784	JJ	denotes	human
T3170	2785-2796	NNS	denotes	populations
T3171	2796-2797	.	denotes	.
T3172	2797-3042	sentence	denotes	Thrombus formation on fissured atherosclerotic plaques is the precipitating event in the transition from a stable or subclinical atherosclerotic disease and leads to acute myocardial infarction, ischemic stroke or peripheral arterial occlusion.
T3173	2798-2806	NN	denotes	Thrombus
T3174	2807-2816	NN	denotes	formation
T3175	2853-2855	VBZ	denotes	is
T3176	2817-2819	IN	denotes	on
T3177	2820-2828	VBN	denotes	fissured
T3178	2845-2852	NNS	denotes	plaques
T3179	2829-2844	JJ	denotes	atherosclerotic
T3180	2856-2859	DT	denotes	the
T3181	2874-2879	NN	denotes	event
T3182	2860-2873	VBG	denotes	precipitating
T3183	2880-2882	IN	denotes	in
T3184	2883-2886	DT	denotes	the
T3185	2887-2897	NN	denotes	transition
T3186	2898-2902	IN	denotes	from
T3187	2903-2904	DT	denotes	a
T3188	2943-2950	NN	denotes	disease
T3189	2905-2911	JJ	denotes	stable
T3190	2912-2914	CC	denotes	or
T3191	2915-2926	JJ	denotes	subclinical
T3192	2927-2942	JJ	denotes	atherosclerotic
T3193	2951-2954	CC	denotes	and
T3194	2955-2960	VBZ	denotes	leads
T3195	2961-2963	IN	denotes	to
T3196	2964-2969	JJ	denotes	acute
T3197	2981-2991	NN	denotes	infarction
T3198	2970-2980	JJ	denotes	myocardial
T3199	2991-2993	,	denotes	,
T3200	2993-3001	JJ	denotes	ischemic
T3201	3002-3008	NN	denotes	stroke
T3202	3009-3011	CC	denotes	or
T3203	3012-3022	JJ	denotes	peripheral
T3204	3023-3031	JJ	denotes	arterial
T3205	3032-3041	NN	denotes	occlusion
T3206	3041-3042	.	denotes	.
T3207	3042-3167	sentence	denotes	Arterial and venous thrombosis are complex responses and are influenced by multiple genetic and environmental factors [2-5].
T3208	3043-3051	JJ	denotes	Arterial
T3209	3063-3073	NN	denotes	thrombosis
T3210	3052-3055	CC	denotes	and
T3211	3056-3062	JJ	denotes	venous
T3212	3074-3077	VBP	denotes	are
T3213	3078-3085	JJ	denotes	complex
T3214	3086-3095	NNS	denotes	responses
T3215	3096-3099	CC	denotes	and
T3216	3100-3103	VBP	denotes	are
T3217	3104-3114	VBN	denotes	influenced
T3218	3115-3117	IN	denotes	by
T3219	3118-3126	JJ	denotes	multiple
T3220	3153-3160	NNS	denotes	factors
T3221	3127-3134	JJ	denotes	genetic
T3222	3135-3138	CC	denotes	and
T3223	3139-3152	JJ	denotes	environmental
T3224	3161-3162	-LRB-	denotes	[
T3225	3162-3163	CD	denotes	2
T3226	3163-3164	SYM	denotes	-
T3227	3164-3165	CD	denotes	5
T3228	3165-3166	-RRB-	denotes	]
T3229	3166-3167	.	denotes	.
T3230	3167-3449	sentence	denotes	Polymorphisms and mutations in coagulation factors, fibrinolytic factors, platelet surface receptors, methylenetetrahydrofalate reductase, endothelial nitric oxide synthase, and antioxidant enzymes have been implicated as genetic determinants of susceptibility to thrombosis [6,7].
T3231	3168-3181	NNS	denotes	Polymorphisms
T3232	3376-3386	VBN	denotes	implicated
T3233	3182-3185	CC	denotes	and
T3234	3186-3195	NNS	denotes	mutations
T3235	3196-3198	IN	denotes	in
T3236	3199-3210	NN	denotes	coagulation
T3237	3211-3218	NNS	denotes	factors
T3238	3218-3220	,	denotes	,
T3239	3220-3232	JJ	denotes	fibrinolytic
T3240	3233-3240	NNS	denotes	factors
T3241	3240-3242	,	denotes	,
T3242	3242-3250	NN	denotes	platelet
T3243	3251-3258	NN	denotes	surface
T3244	3259-3268	NNS	denotes	receptors
T3245	3268-3270	,	denotes	,
T3246	3270-3295	NN	denotes	methylenetetrahydrofalate
T3247	3296-3305	NN	denotes	reductase
T3248	3305-3307	,	denotes	,
T3249	3307-3318	JJ	denotes	endothelial
T3250	3332-3340	NN	denotes	synthase
T3251	3319-3325	JJ	denotes	nitric
T3252	3326-3331	NN	denotes	oxide
T3253	3340-3342	,	denotes	,
T3254	3342-3345	CC	denotes	and
T3255	3346-3357	JJ	denotes	antioxidant
T3256	3358-3365	NNS	denotes	enzymes
T3257	3366-3370	VBP	denotes	have
T3258	3371-3375	VBN	denotes	been
T3259	3387-3389	IN	denotes	as
T3260	3390-3397	JJ	denotes	genetic
T3261	3398-3410	NNS	denotes	determinants
T3262	3411-3413	IN	denotes	of
T3263	3414-3428	NN	denotes	susceptibility
T3264	3429-3431	IN	denotes	to
T3265	3432-3442	NN	denotes	thrombosis
T3266	3443-3444	-LRB-	denotes	[
T3267	3446-3447	CD	denotes	7
T3268	3444-3445	CD	denotes	6
T3269	3445-3446	,	denotes	,
T3270	3447-3448	-RRB-	denotes	]
T3271	3448-3449	.	denotes	.
T3272	3449-3543	sentence	denotes	Great strides have been made in the diagnosis and treatment of thrombosis in the last decade.
T3273	3450-3455	JJ	denotes	Great
T3274	3456-3463	NNS	denotes	strides
T3275	3474-3478	VBN	denotes	made
T3276	3464-3468	VBP	denotes	have
T3277	3469-3473	VBN	denotes	been
T3278	3479-3481	IN	denotes	in
T3279	3482-3485	DT	denotes	the
T3280	3486-3495	NN	denotes	diagnosis
T3281	3496-3499	CC	denotes	and
T3282	3500-3509	NN	denotes	treatment
T3283	3510-3512	IN	denotes	of
T3284	3513-3523	NN	denotes	thrombosis
T3285	3524-3526	IN	denotes	in
T3286	3527-3530	DT	denotes	the
T3287	3536-3542	NN	denotes	decade
T3288	3531-3535	JJ	denotes	last
T3289	3542-3543	.	denotes	.
T3290	3543-3723	sentence	denotes	However, strategies to prevent thrombosis have lagged far behind due, in part, to the contribution of multiple, and as yet undefined, genetic factors that lead to thrombotic risk.
T3291	3544-3551	RB	denotes	However
T3292	3591-3597	VBN	denotes	lagged
T3293	3551-3553	,	denotes	,
T3294	3553-3563	NNS	denotes	strategies
T3295	3564-3566	TO	denotes	to
T3296	3567-3574	VB	denotes	prevent
T3297	3575-3585	NN	denotes	thrombosis
T3298	3586-3590	VBP	denotes	have
T3299	3598-3601	RB	denotes	far
T3300	3602-3608	RB	denotes	behind
T3301	3609-3612	IN	denotes	due
T3302	3612-3614	,	denotes	,
T3303	3614-3616	IN	denotes	in
T3304	3617-3621	JJ	denotes	part
T3305	3621-3623	,	denotes	,
T3306	3623-3625	IN	denotes	to
T3307	3626-3629	DT	denotes	the
T3308	3630-3642	NN	denotes	contribution
T3309	3643-3645	IN	denotes	of
T3310	3646-3654	JJ	denotes	multiple
T3311	3686-3693	NNS	denotes	factors
T3312	3654-3656	,	denotes	,
T3313	3656-3659	CC	denotes	and
T3314	3660-3662	RB	denotes	as
T3315	3663-3666	RB	denotes	yet
T3316	3667-3676	JJ	denotes	undefined
T3317	3676-3678	,	denotes	,
T3318	3678-3685	JJ	denotes	genetic
T3319	3694-3698	WDT	denotes	that
T3320	3699-3703	VBP	denotes	lead
T3321	3704-3706	IN	denotes	to
T3322	3707-3717	JJ	denotes	thrombotic
T3323	3718-3722	NN	denotes	risk
T3324	3722-3723	.	denotes	.
T3325	3723-3933	sentence	denotes	Moreover, it remains unclear how genetic background influences the function of molecules and pathways known to regulate thrombus formation and lysis and, thereby, contributes to the risk of thrombotic disease.
T3326	3724-3732	RB	denotes	Moreover
T3327	3737-3744	VBZ	denotes	remains
T3328	3732-3734	,	denotes	,
T3329	3734-3736	PRP	denotes	it
T3330	3745-3752	JJ	denotes	unclear
T3331	3753-3756	WRB	denotes	how
T3332	3776-3786	VBZ	denotes	influences
T3333	3757-3764	JJ	denotes	genetic
T3334	3765-3775	NN	denotes	background
T3335	3787-3790	DT	denotes	the
T3336	3791-3799	NN	denotes	function
T3337	3800-3802	IN	denotes	of
T3338	3803-3812	NNS	denotes	molecules
T3339	3813-3816	CC	denotes	and
T3340	3817-3825	NNS	denotes	pathways
T3341	3826-3831	VBN	denotes	known
T3342	3832-3834	TO	denotes	to
T3343	3835-3843	VB	denotes	regulate
T3344	3844-3852	NN	denotes	thrombus
T3345	3853-3862	NN	denotes	formation
T3346	3863-3866	CC	denotes	and
T3347	3867-3872	NN	denotes	lysis
T3348	3873-3876	CC	denotes	and
T3349	3876-3878	,	denotes	,
T3350	3878-3885	RB	denotes	thereby
T3351	3887-3898	VBZ	denotes	contributes
T3352	3885-3887	,	denotes	,
T3353	3899-3901	IN	denotes	to
T3354	3902-3905	DT	denotes	the
T3355	3906-3910	NN	denotes	risk
T3356	3911-3913	IN	denotes	of
T3357	3914-3924	JJ	denotes	thrombotic
T3358	3925-3932	NN	denotes	disease
T3359	3932-3933	.	denotes	.
T3360	3933-4099	sentence	denotes	Many of the available inbred mouse strains, such as C57BL/6J (B6) and A/J, have been classified as resistant or susceptible to particular complex diseases (Table 1).
T3361	3934-3938	JJ	denotes	Many
T3362	4019-4029	VBN	denotes	classified
T3363	3939-3941	IN	denotes	of
T3364	3942-3945	DT	denotes	the
T3365	3969-3976	NNS	denotes	strains
T3366	3946-3955	JJ	denotes	available
T3367	3956-3962	JJ	denotes	inbred
T3368	3963-3968	NN	denotes	mouse
T3369	3976-3978	,	denotes	,
T3370	3978-3982	JJ	denotes	such
T3371	3983-3985	IN	denotes	as
T3372	3986-3991	NN	denotes	C57BL
T3373	3992-3994	NN	denotes	6J
T3374	3991-3992	HYPH	denotes	/
T3375	3995-3996	-LRB-	denotes	(
T3376	3996-3998	NN	denotes	B6
T3377	3998-3999	-RRB-	denotes	)
T3378	4000-4003	CC	denotes	and
T3379	4004-4005	NN	denotes	A
T3380	4006-4007	NN	denotes	J
T3381	4005-4006	HYPH	denotes	/
T3382	4007-4009	,	denotes	,
T3383	4009-4013	VBP	denotes	have
T3384	4014-4018	VBN	denotes	been
T3385	4030-4032	IN	denotes	as
T3386	4033-4042	JJ	denotes	resistant
T3387	4043-4045	CC	denotes	or
T3388	4046-4057	JJ	denotes	susceptible
T3389	4058-4060	IN	denotes	to
T3390	4061-4071	JJ	denotes	particular
T3391	4080-4088	NNS	denotes	diseases
T3392	4072-4079	JJ	denotes	complex
T3393	4089-4090	-LRB-	denotes	(
T3394	4090-4095	NN	denotes	Table
T3395	4096-4097	CD	denotes	1
T3396	4097-4098	-RRB-	denotes	)
T3397	4098-4099	.	denotes	.
T3398	4099-4424	sentence	denotes	These two strains have diverse responses to diet-induced obesity [8] (B6 susceptible; A/J resistant), diet-induced atherosclerosis (B6 susceptible; A/J resistant) [9], arterial ligation-induced neointimal hyperplasia (B6 resistant; A/J resistant), and ligation induced vessel remodeling (B6 resistant; A/J susceptible) [10].
T3399	4100-4105	DT	denotes	These
T3400	4110-4117	NNS	denotes	strains
T3401	4106-4109	CD	denotes	two
T3402	4118-4122	VBP	denotes	have
T3403	4123-4130	JJ	denotes	diverse
T3404	4131-4140	NNS	denotes	responses
T3405	4141-4143	IN	denotes	to
T3406	4144-4148	NN	denotes	diet
T3407	4149-4156	VBN	denotes	induced
T3408	4148-4149	HYPH	denotes	-
T3409	4157-4164	NN	denotes	obesity
T3410	4165-4166	-LRB-	denotes	[
T3411	4166-4167	CD	denotes	8
T3412	4167-4168	-RRB-	denotes	]
T3413	4169-4170	-LRB-	denotes	(
T3414	4190-4199	JJ	denotes	resistant
T3415	4170-4172	NN	denotes	B6
T3416	4173-4184	JJ	denotes	susceptible
T3417	4184-4185	:	denotes	;
T3418	4186-4187	NN	denotes	A
T3419	4188-4189	NN	denotes	J
T3420	4187-4188	HYPH	denotes	/
T3421	4199-4200	-RRB-	denotes	)
T3422	4200-4202	,	denotes	,
T3423	4202-4206	NN	denotes	diet
T3424	4207-4214	VBN	denotes	induced
T3425	4206-4207	HYPH	denotes	-
T3426	4215-4230	NN	denotes	atherosclerosis
T3427	4231-4232	-LRB-	denotes	(
T3428	4252-4261	JJ	denotes	resistant
T3429	4232-4234	NN	denotes	B6
T3430	4235-4246	JJ	denotes	susceptible
T3431	4246-4247	:	denotes	;
T3432	4248-4249	NN	denotes	A
T3433	4250-4251	NN	denotes	J
T3434	4249-4250	HYPH	denotes	/
T3435	4261-4262	-RRB-	denotes	)
T3436	4263-4264	-LRB-	denotes	[
T3437	4264-4265	CD	denotes	9
T3438	4265-4266	-RRB-	denotes	]
T3439	4266-4268	,	denotes	,
T3440	4268-4276	JJ	denotes	arterial
T3441	4277-4285	NN	denotes	ligation
T3442	4286-4293	VBN	denotes	induced
T3443	4285-4286	HYPH	denotes	-
T3444	4305-4316	NN	denotes	hyperplasia
T3445	4294-4304	JJ	denotes	neointimal
T3446	4317-4318	-LRB-	denotes	(
T3447	4336-4345	JJ	denotes	resistant
T3448	4318-4320	NN	denotes	B6
T3449	4321-4330	JJ	denotes	resistant
T3450	4330-4331	:	denotes	;
T3451	4332-4333	NN	denotes	A
T3452	4334-4335	NN	denotes	J
T3453	4333-4334	HYPH	denotes	/
T3454	4345-4346	-RRB-	denotes	)
T3455	4346-4348	,	denotes	,
T3456	4348-4351	CC	denotes	and
T3457	4352-4360	NN	denotes	ligation
T3458	4361-4368	VBN	denotes	induced
T3459	4376-4386	NN	denotes	remodeling
T3460	4369-4375	NN	denotes	vessel
T3461	4387-4388	-LRB-	denotes	(
T3462	4420-4422	CD	denotes	10
T3463	4388-4390	NN	denotes	B6
T3464	4391-4400	JJ	denotes	resistant
T3467	4404-4405	NN	denotes	J
T3468	4403-4404	HYPH	denotes	/
T3469	4406-4417	JJ	denotes	susceptible
T3470	4417-4418	-RRB-	denotes	)
T3471	4419-4420	-LRB-	denotes	[
T3472	4422-4423	-RRB-	denotes	]
T3473	4423-4424	.	denotes	.
T3474	4424-4550	sentence	denotes	These conditions are predisposing to thrombosis per se, but these mice have not been systematically evaluated for thrombosis.
T3475	4425-4430	DT	denotes	These
T3476	4431-4441	NNS	denotes	conditions
T3477	4442-4445	VBP	denotes	are
T3478	4446-4458	VBG	denotes	predisposing
T3479	4459-4461	IN	denotes	to
T3480	4462-4472	NN	denotes	thrombosis
T3481	4473-4476	FW	denotes	per
T3482	4477-4479	FW	denotes	se
T3483	4479-4481	,	denotes	,
T3484	4481-4484	CC	denotes	but
T3485	4485-4490	DT	denotes	these
T3486	4491-4495	NNS	denotes	mice
T3487	4525-4534	VBN	denotes	evaluated
T3488	4496-4500	VBP	denotes	have
T3489	4501-4504	RB	denotes	not
T3490	4505-4509	VBN	denotes	been
T3491	4510-4524	RB	denotes	systematically
T3492	4535-4538	IN	denotes	for
T3493	4539-4549	NN	denotes	thrombosis
T3494	4549-4550	.	denotes	.
T3495	4550-4687	sentence	denotes	Clot formation and lysis, which ultimately determine thrombosis, requires platelet aggregation, coagulation, and fibrinolytic functions.
T3496	4551-4555	NN	denotes	Clot
T3497	4556-4565	NN	denotes	formation
T3498	4616-4624	VBZ	denotes	requires
T3499	4566-4569	CC	denotes	and
T3500	4570-4575	NN	denotes	lysis
T3501	4575-4577	,	denotes	,
T3502	4577-4582	WDT	denotes	which
T3503	4594-4603	VBP	denotes	determine
T3504	4583-4593	RB	denotes	ultimately
T3505	4604-4614	NN	denotes	thrombosis
T3506	4614-4616	,	denotes	,
T3507	4625-4633	NN	denotes	platelet
T3508	4634-4645	NN	denotes	aggregation
T3509	4645-4647	,	denotes	,
T3510	4647-4658	NN	denotes	coagulation
T3511	4658-4660	,	denotes	,
T3512	4660-4663	CC	denotes	and
T3513	4664-4676	JJ	denotes	fibrinolytic
T3514	4677-4686	NNS	denotes	functions
T3515	4686-4687	.	denotes	.
T3516	4687-4784	sentence	denotes	Interactions among these pathways may occur and additional factors may modulate these processes.
T3517	4688-4700	NNS	denotes	Interactions
T3518	4726-4731	VB	denotes	occur
T3519	4701-4706	IN	denotes	among
T3520	4707-4712	DT	denotes	these
T3521	4713-4721	NNS	denotes	pathways
T3522	4722-4725	MD	denotes	may
T3523	4732-4735	CC	denotes	and
T3524	4736-4746	JJ	denotes	additional
T3525	4747-4754	NNS	denotes	factors
T3526	4759-4767	VB	denotes	modulate
T3527	4755-4758	MD	denotes	may
T3528	4768-4773	DT	denotes	these
T3529	4774-4783	NNS	denotes	processes
T3530	4783-4784	.	denotes	.
T3531	4784-4975	sentence	denotes	Identification of novel modulators and factors of these pathways can be identified by associating the phenotype with a location(s) on a specific chromosome, a quantitative trait locus (QTL).
T3532	4785-4799	NN	denotes	Identification
T3533	4857-4867	VBN	denotes	identified
T3534	4800-4802	IN	denotes	of
T3535	4803-4808	JJ	denotes	novel
T3536	4809-4819	NNS	denotes	modulators
T3537	4820-4823	CC	denotes	and
T3538	4824-4831	NNS	denotes	factors
T3539	4832-4834	IN	denotes	of
T3540	4835-4840	DT	denotes	these
T3541	4841-4849	NNS	denotes	pathways
T3542	4850-4853	MD	denotes	can
T3543	4854-4856	VB	denotes	be
T3544	4868-4870	IN	denotes	by
T3545	4871-4882	VBG	denotes	associating
T3546	4883-4886	DT	denotes	the
T3547	4887-4896	NN	denotes	phenotype
T3548	4897-4901	IN	denotes	with
T3549	4902-4903	DT	denotes	a
T3550	4904-4912	NN	denotes	location
T3551	4912-4913	-LRB-	denotes	(
T3552	4913-4914	AFX	denotes	s
T3553	4914-4915	-RRB-	denotes	)
T3554	4916-4918	IN	denotes	on
T3555	4919-4920	DT	denotes	a
T3556	4930-4940	NN	denotes	chromosome
T3557	4921-4929	JJ	denotes	specific
T3558	4940-4942	,	denotes	,
T3559	4942-4943	DT	denotes	a
T3560	4963-4968	NN	denotes	locus
T3561	4944-4956	JJ	denotes	quantitative
T3562	4957-4962	NN	denotes	trait
T3563	4969-4970	-LRB-	denotes	(
T3564	4970-4973	NN	denotes	QTL
T3565	4973-4974	-RRB-	denotes	)
T3566	4974-4975	.	denotes	.
T3567	4975-4976	sentence	denotes
T3928	7278-7279	.	denotes	.
T19543	32959-32961	NNP	denotes	J.
T22759	26484-26493	VB	denotes	determine
T22758	26481-26483	TO	denotes	to
T22757	26472-26475	VBD	denotes	was
T22756	26476-26480	VBN	denotes	made
T22755	26450-26460	NNP	denotes	Bonferroni
T22754	26461-26471	NN	denotes	correction
T22753	26448-26449	DT	denotes	a
T22752	26444-26447	CC	denotes	and
T22751	26442-26444	,	denotes	,
T22750	26437-26438	HYPH	denotes	-
T22749	26436-26437	NN	denotes	t
T22748	26438-26442	NN	denotes	test
T22747	26434-26435	DT	denotes	a
T22746	26429-26433	IN	denotes	with
T22745	26413-26417	VBD	denotes	were
T22744	26409-26412	NN	denotes	CSS
T22743	26405-26408	CC	denotes	and
T22742	26400-26404	NNS	denotes	mice
T22741	26397-26399	NN	denotes	B6
T22740	26389-26396	IN	denotes	between
T22739	26418-26428	VBN	denotes	determined
T22738	26377-26388	NNS	denotes	differences
T22737	26365-26376	JJ	denotes	Statistical
T22736	26364-26524	sentence	denotes	Statistical differences between B6 mice and CSS were determined with a t-test, and a Bonferroni correction was made to determine significance value (P < 0.01).
T22735	26363-26364	.	denotes	.
T22734	26359-26363	NNS	denotes	mice
T22733	26355-26356	SYM	denotes	–
T22732	26356-26358	CD	denotes	18
T22731	26354-26355	CD	denotes	5
T22730	26351-26353	IN	denotes	of
T22729	26345-26346	SYM	denotes	±
T22728	26340-26344	NN	denotes	mean
T22727	26347-26350	NN	denotes	SEM
T22726	26336-26339	DT	denotes	the
T22725	26332-26335	VBP	denotes	are
T22724	26327-26331	NNS	denotes	Bars
T22723	26326-26364	sentence	denotes	Bars are the mean ± SEM of 5–18 mice.
T22722	26325-26326	.	denotes	.
T22721	26324-26325	-RRB-	denotes	)
T22720	26320-26321	SYM	denotes	×
T22719	26322-26324	CD	denotes	17
T22718	26318-26319	CD	denotes	5
T22717	26317-26318	-LRB-	denotes	(
T22716	26314-26316	CD	denotes	17
T22705	26257-26258	-LRB-	denotes	(
T22704	26253-26254	-RRB-	denotes	)
T22703	26251-26253	CD	denotes	17
T22702	26250-26251	HYPH	denotes	-
T22701	26244-26250	NN	denotes	B6xCSS
T22700	26254-26256	NN	denotes	F1
T22699	26243-26244	-LRB-	denotes	(
T22698	26239-26242	CC	denotes	and
T22697	26237-26238	-RRB-	denotes	)
T22696	26234-26237	NN	denotes	5F1
T22695	26233-26234	-LRB-	denotes	(
T22694	26229-26230	-RRB-	denotes	)
T22693	26228-26229	CD	denotes	5
T22692	26227-26228	HYPH	denotes	-
T22691	26221-26227	NN	denotes	B6xCSS
T22690	26230-26232	NN	denotes	F1
T22689	26220-26221	-LRB-	denotes	(
T22688	26218-26220	,	denotes	,
T22687	26214-26218	NNS	denotes	mice
T22686	26202-26213	JJ	denotes	heterosomic
T22685	26199-26201	IN	denotes	in
T22684	26187-26191	VBD	denotes	were
T22683	26185-26186	-RRB-	denotes	)
T22682	26183-26185	NN	denotes	mL
T23066	27703-27707	NNS	denotes	mice
T23065	27700-27702	NN	denotes	B6
T23064	27692-27699	IN	denotes	between
T23063	27721-27731	VBN	denotes	determined
T23062	27680-27691	NNS	denotes	differences
T23061	27668-27679	JJ	denotes	Statistical
T23060	27667-27827	sentence	denotes	Statistical differences between B6 mice and CSS were determined with a t-test, and a Bonferroni correction was made to determine significance value (P < 0.02).
T23059	27666-27667	.	denotes	.
T23058	27662-27666	NNS	denotes	mice
T23057	27658-27659	SYM	denotes	–
T23056	27659-27661	CD	denotes	18
T23055	27657-27658	CD	denotes	5
T23054	27654-27656	IN	denotes	of
T23053	27648-27649	SYM	denotes	±
T23052	27643-27647	NN	denotes	mean
T23051	27650-27653	NN	denotes	SEM
T23050	27639-27642	DT	denotes	the
T23049	27635-27638	VBP	denotes	are
T23048	27630-27634	NNS	denotes	Bars
T23047	27629-27667	sentence	denotes	Bars are the mean ± SEM of 5–18 mice.
T23046	27628-27629	.	denotes	.
T23045	27627-27628	-RRB-	denotes	)
T23044	27623-27624	SYM	denotes	×
T23043	27625-27627	CD	denotes	17
T23042	27621-27622	CD	denotes	5
T23041	27620-27621	-LRB-	denotes	(
T23040	27617-27619	CD	denotes	17
T23039	27613-27616	CC	denotes	and
T23038	27611-27612	CD	denotes	5
T23037	27599-27610	NNS	denotes	chromosomes
T23036	27595-27598	IN	denotes	for
T23035	27590-27594	NNS	denotes	mice
T23034	27578-27589	JJ	denotes	heterosomic
T23033	27571-27577	RB	denotes	doubly
T23032	27567-27570	CC	denotes	and
T23031	27565-27567	,	denotes	,
T23030	27564-27565	-RRB-	denotes	)
T23029	27560-27564	NN	denotes	17F1
T23028	27559-27560	-LRB-	denotes	(
T22381	24331-24332	NN	denotes	P
T22380	24335-24339	CD	denotes	0.01
T22379	24330-24331	SYM	denotes	*
T22378	24329-24340	sentence	denotes	*P < 0.01.
T22377	24328-24329	.	denotes	.
T22376	24322-24328	NNS	denotes	values
T22375	24319-24321	NN	denotes	B6
T22374	24311-24318	IN	denotes	between
T22373	24288-24299	JJ	denotes	significant
T22372	24300-24310	NN	denotes	difference
T22371	24286-24287	DT	denotes	a
T22370	24277-24285	VBP	denotes	indicate
T22369	24269-24276	NNS	denotes	Symbols
T22327	24085-24086	SYM	denotes	±
T22326	24080-24084	NN	denotes	mean
T22325	24087-24090	NN	denotes	SEM
T22324	24076-24079	DT	denotes	the
T22323	24072-24075	VBP	denotes	are
T22322	24067-24071	NNS	denotes	Bars
T22321	24066-24104	sentence	denotes	Bars are the mean ± SEM of 5–28 mice.
T22320	24065-24066	.	denotes	.
T22319	24064-24065	-RRB-	denotes	)
T22318	24060-24061	SYM	denotes	×
T22317	24062-24064	CD	denotes	17
T22316	24058-24059	CD	denotes	5
T22315	24057-24058	-LRB-	denotes	(
T22314	24054-24056	CD	denotes	17
T22313	24050-24053	CC	denotes	and
T22312	24048-24049	CD	denotes	5
T22311	24036-24047	NNS	denotes	chromosomes
T22310	24032-24035	IN	denotes	for
T22309	24027-24031	NNS	denotes	mice
T22308	24015-24026	JJ	denotes	heterosomic
T22307	24008-24014	RB	denotes	doubly
T22306	24004-24007	CC	denotes	and
T22305	24002-24003	-RRB-	denotes	)
T22304	23998-24002	NN	denotes	17F1
T22303	23997-23998	-LRB-	denotes	(
T22258	23831-23833	IN	denotes	in
T22257	23815-23825	NN	denotes	rebleeding
T22256	23811-23814	CC	denotes	and
T22255	23826-23830	NN	denotes	time
T22254	23802-23810	NN	denotes	Bleeding
T23107	27900-27901	.	denotes	.
T23106	27892-27893	SYM	denotes	<
T23105	27894-27900	CD	denotes	0.0001
T23104	27890-27891	NN	denotes	P
T23103	27889-27890	SYM	denotes	*
T23102	27888-27901	sentence	denotes	*P < 0.0001.
T23101	27887-27888	.	denotes	.
T23100	27881-27887	NNS	denotes	values
T23099	27878-27880	NN	denotes	B6
T23098	27870-27877	IN	denotes	between
T23097	27847-27858	JJ	denotes	significant
T23096	27859-27869	NN	denotes	difference
T23095	27845-27846	DT	denotes	a
T23094	27836-27844	VBP	denotes	indicate
T23093	27828-27835	NNS	denotes	Symbols
T23092	27827-27888	sentence	denotes	Symbols indicate a significant difference between B6 values.
T23091	27826-27827	.	denotes	.
T23090	27825-27826	-RRB-	denotes	)
T23089	27819-27820	SYM	denotes	<
T23088	27817-27818	NN	denotes	P
T22681	26182-26183	SYM	denotes	/
T22680	26181-26182	NNS	denotes	U
T22679	26180-26181	-LRB-	denotes	(
T22678	26169-26170	CD	denotes	1
T22677	26168-26169	HYPH	denotes	-
T22676	26165-26168	NN	denotes	PAI
T22675	26171-26179	NN	denotes	activity
T22674	26158-26164	NN	denotes	Plasma
T22673	26156-26158	:	denotes	:
T22672	26155-26156	NN	denotes	B
T22671	26149-26154	NN	denotes	Panel
T22670	26145-26148	CC	denotes	and
T22669	26143-26144	-RRB-	denotes	)
T22668	26141-26143	NN	denotes	mL
T22667	26140-26141	SYM	denotes	/
T22666	26138-26140	NNS	denotes	ng
T22665	26137-26138	-LRB-	denotes	(
T22664	26127-26128	CD	denotes	1
T22663	26126-26127	HYPH	denotes	-
T22662	26123-26126	NN	denotes	PAI
T22661	26129-26136	NN	denotes	antigen
T22660	26116-26122	NN	denotes	Plasma
T22659	26114-26116	:	denotes	:
T22658	26192-26198	VBN	denotes	tested
T22657	26113-26114	NN	denotes	A
T22656	26107-26112	NN	denotes	Panel
T22655	26106-26326	sentence	denotes	Panel A: Plasma PAI-1 antigen (ng/mL) and Panel B: Plasma PAI-1 activity (U/mL) were tested in heterosomic mice, (B6xCSS-5)F1 (5F1) and (B6xCSS-17)F1 (17F1) and doubly heterosomic mice for chromosomes 5 and 17 (5 × 17).
T22654	26105-26106	.	denotes	.
T22653	26090-26093	NN	denotes	CSS
T22652	26094-26105	NNS	denotes	backcrosses
T22651	26086-26089	DT	denotes	the
T22650	26083-26085	IN	denotes	in
T22649	26081-26082	CD	denotes	1
T22648	26080-26081	HYPH	denotes	-
T22647	26077-26080	NN	denotes	PAI
T21949	22707-22708	NN	denotes	B
T21948	22701-22706	NN	denotes	Panel
T21947	22700-22736	sentence	denotes	Panel B: Rebleeding Time (seconds).
T21946	22699-22700	.	denotes	.
T21945	22698-22699	-RRB-	denotes	)
T21944	22691-22698	NNS	denotes	seconds
T21943	22690-22691	-LRB-	denotes	(
T21942	22685-22689	NN	denotes	Time
T21941	22676-22684	NN	denotes	Bleeding
T21940	22674-22676	:	denotes	:
T21939	22673-22674	NN	denotes	A
T21938	22667-22672	NN	denotes	Panel
T21937	22666-22700	sentence	denotes	Panel A: Bleeding Time (seconds).
T21936	22665-22666	.	denotes	.
T21935	22662-22665	NN	denotes	CSS
T21934	22658-22661	DT	denotes	the
T21933	22655-22657	IN	denotes	in
T21932	22639-22649	NN	denotes	rebleeding
T21931	22635-22638	CC	denotes	and
T21930	22650-22654	NN	denotes	time
T21929	22626-22634	NN	denotes	Bleeding
T22368	24268-24329	sentence	denotes	Symbols indicate a significant difference between B6 values.
T22367	24267-24268	.	denotes	.
T22366	24266-24267	-RRB-	denotes	)
T22365	24260-24261	SYM	denotes	<
T22364	24258-24259	NN	denotes	P
T22363	24262-24266	CD	denotes	0.01
T22362	24257-24258	-LRB-	denotes	(
T22361	24251-24256	NN	denotes	value
T22360	24238-24250	NN	denotes	significance
T22359	24228-24237	VB	denotes	determine
T22358	24225-24227	TO	denotes	to
T22357	24216-24219	VBD	denotes	was
T22356	24220-24224	VBN	denotes	made
T22355	24194-24204	NNP	denotes	Bonferroni
T22354	24205-24215	NN	denotes	correction
T22353	24192-24193	DT	denotes	a
T22352	24188-24191	CC	denotes	and
T22351	24186-24188	,	denotes	,
T22350	24181-24182	HYPH	denotes	-
T22349	24180-24181	NN	denotes	t
T22348	24182-24186	NN	denotes	test
T22347	24178-24179	DT	denotes	a
T22346	24173-24177	IN	denotes	with
T22345	24157-24161	VBD	denotes	were
T22344	24153-24156	NN	denotes	CSS
T22343	24149-24152	DT	denotes	the
T22342	24145-24148	CC	denotes	and
T22341	24140-24144	NNS	denotes	mice
T22340	24137-24139	NN	denotes	B6
T22339	24129-24136	IN	denotes	between
T22338	24162-24172	VBN	denotes	determined
T22337	24117-24128	NNS	denotes	differences
T22336	24105-24116	JJ	denotes	Statistical
T22335	24104-24268	sentence	denotes	Statistical differences between B6 mice and the CSS were determined with a t-test, and a Bonferroni correction was made to determine significance value (P < 0.01).
T22334	24103-24104	.	denotes	.
T22333	24099-24103	NNS	denotes	mice
T22332	24096-24097	CD	denotes	2
T22331	24095-24096	SYM	denotes	–
T22330	24097-24098	CD	denotes	8
T22329	24094-24095	CD	denotes	5
T22328	24091-24093	IN	denotes	of
T21753	21415-21419	CD	denotes	0.05
T21752	21409-21410	-LRB-	denotes	(
T21751	21386-21397	JJ	denotes	significant
T21750	21398-21408	NN	denotes	difference
T21749	21384-21385	DT	denotes	a
T21748	21374-21383	VBZ	denotes	indicates
T21747	21367-21373	NN	denotes	Symbol
T21746	21366-21458	sentence	denotes	Symbol indicates a significant difference (*P < 0.05) between B6 mice determined by t-test.
T21745	21365-21366	.	denotes	.
T21744	21357-21365	NN	denotes	genotype
T21743	21353-21356	IN	denotes	per
T21742	21348-21352	NNS	denotes	mice
T21741	21345-21346	SYM	denotes	–
T21740	21346-21347	CD	denotes	8
T21739	21344-21345	CD	denotes	4
T21738	21341-21343	IN	denotes	of
T21737	21335-21336	SYM	denotes	±
T21736	21330-21334	NN	denotes	mean
T21735	21337-21340	NN	denotes	SEM
T21734	21326-21329	DT	denotes	the
T21733	21322-21325	VBP	denotes	are
T21732	21315-21321	NNS	denotes	Values
T21731	21314-21366	sentence	denotes	Values are the mean ± SEM of 4–8 mice per genotype.
T21730	21313-21314	.	denotes	.
T21729	21308-21313	NN	denotes	mouse
T21728	21303-21307	DT	denotes	each
T21727	21299-21302	IN	denotes	for
T21726	21290-21298	VBD	denotes	averaged
T21725	21286-21289	CC	denotes	and
T21724	21281-21285	NN	denotes	tail
T21723	21276-21280	DT	denotes	each
T21722	21272-21275	IN	denotes	for
T21721	21266-21271	NNS	denotes	sites
T21720	21263-21264	SYM	denotes	–
T21719	21264-21265	CD	denotes	3
T21718	21262-21263	CD	denotes	2
T21717	21259-21261	IN	denotes	at
T21716	21250-21258	NNS	denotes	sections
T21715	21247-21248	SYM	denotes	–
T21714	21248-21249	CD	denotes	4
T21713	21246-21247	CD	denotes	3
T21712	21243-21245	IN	denotes	in
T21711	21228-21231	VBD	denotes	was
T21710	21220-21227	NN	denotes	section
T21709	21215-21219	DT	denotes	each
T21708	21212-21214	IN	denotes	of
T21707	21202-21206	NN	denotes	tail
T21706	21196-21201	JJ	denotes	total
T21705	21207-21211	NN	denotes	area
T21704	21192-21195	DT	denotes	the
T21703	21189-21191	IN	denotes	of
T21702	21187-21188	-RRB-	denotes	)
T21701	21178-21187	NN	denotes	cartilage
T21700	21177-21178	HYPH	denotes	/
T21699	21173-21177	NN	denotes	bone
T21698	21166-21172	NN	denotes	center
T21697	21156-21165	VBG	denotes	excluding
T21696	21155-21156	-LRB-	denotes	(
T21695	21141-21149	NN	denotes	collagen
T21694	21150-21154	NN	denotes	area
T21693	21137-21140	DT	denotes	the
T21692	21134-21136	IN	denotes	of
T21691	21123-21133	NN	denotes	percentage
T21690	21119-21122	DT	denotes	The
T21689	21117-21119	:	denotes	:
T21688	21232-21242	VBN	denotes	determined
T21687	21116-21117	NN	denotes	C
T21686	21110-21115	NN	denotes	Panel
T21685	21109-21314	sentence	denotes	Panel C: The percentage of the collagen area (excluding center bone/cartilage) of the total tail area of each section was determined in 3–4 sections at 2–3 sites for each tail and averaged for each mouse.
T21684	21108-21109	.	denotes	.
T21683	21100-21108	NN	denotes	collagen
T21682	21096-21099	DT	denotes	the
T21681	21085-21095	VBZ	denotes	identifies
T21680	21074-21078	JJ	denotes	blue
T21679	21079-21084	NN	denotes	color
T21678	21070-21073	DT	denotes	The
T21677	21069-21109	sentence	denotes	The blue color identifies the collagen.
T21676	21068-21069	.	denotes	.
T21675	21061-21062	HYPH	denotes	/
T21674	21062-21063	NN	denotes	J
T21666	21029-21035	NNP	denotes	Masson
T21665	21024-21028	IN	denotes	with
T21664	21016-21023	VBN	denotes	stained
T21663	21007-21015	NNS	denotes	sections
T21662	20992-21006	JJ	denotes	Representative
T21661	20990-20992	:	denotes	:
T21660	20989-20990	NN	denotes	B
T21659	20983-20988	NN	denotes	Panel
T21658	20982-21069	sentence	denotes	Panel B: Representative sections stained with Masson's Trichrome from B6 and A/J mice.
T21657	20981-20982	.	denotes	.
T21656	20974-20975	HYPH	denotes	/
T21655	20975-20976	NN	denotes	J
T21654	20973-20974	NN	denotes	A
T21653	20969-20972	CC	denotes	and
T21652	20977-20981	NNS	denotes	mice
T21651	20966-20968	NN	denotes	B6
T21650	20961-20965	IN	denotes	from
T21649	20955-20960	NN	denotes	eosin
T21648	20951-20954	CC	denotes	and
T21647	20939-20950	NN	denotes	hematoxylin
T21646	20934-20938	IN	denotes	with
T21645	20926-20933	VBN	denotes	stained
T21644	20917-20925	NNS	denotes	sections
T21643	20902-20916	JJ	denotes	Representative
T21642	20900-20902	:	denotes	:
T21641	20899-20900	NN	denotes	A
T21640	20893-20898	NN	denotes	Panel
T21639	20892-20982	sentence	denotes	Panel A: Representative sections stained with hematoxylin and eosin from B6 and A/J mice.
T21638	20891-20892	.	denotes	.
T21637	20879-20881	POS	denotes	's
T21636	20882-20891	NN	denotes	Trichrome
T21635	20873-20879	NNP	denotes	Masson
T21634	20870-20872	CC	denotes	or
T21633	20863-20864	HYPH	denotes	/
T21632	20864-20869	NN	denotes	Eosin
T21631	20852-20863	NN	denotes	Hematoxylin
T21630	20847-20851	IN	denotes	with
T21629	20839-20846	VBD	denotes	stained
T21628	20835-20838	CC	denotes	and
T21627	20833-20835	,	denotes	,
T21626	20824-20833	VBN	denotes	sectioned
T21625	20822-20824	,	denotes	,
T21624	20819-20822	NN	denotes	OCT
T21623	20816-20818	IN	denotes	in
T21622	20807-20815	VBN	denotes	embedded
T21621	20805-20807	,	denotes	,
T21620	20793-20797	VBD	denotes	were
T21619	20798-20805	VBN	denotes	excised
T21618	20787-20792	NNS	denotes	Tails
T21617	20786-20892	sentence	denotes	Tails were excised, embedded in OCT, sectioned, and stained with Hematoxylin/Eosin or Masson's Trichrome.
T21616	20785-20786	.	denotes	.
T21615	20777-20785	NN	denotes	collagen
T21614	20773-20776	CC	denotes	and
T21613	20762-20772	NN	denotes	morphology
T21612	20757-20761	NN	denotes	Tail
T21766	21457-21458	.	denotes	.
T21765	21452-21453	HYPH	denotes	-
T21764	21453-21457	NN	denotes	test
T21259	16145-16248	sentence	denotes	Symbols indicate a significant difference (P < 0.05, P < 0.01, **P < 0.001) between B6 or WT mice.
T21258	16144-16145	.	denotes	.
T21257	16128-16129	HYPH	denotes	-
T21256	16129-16134	NNP	denotes	Keuls
T21255	16122-16128	NNP	denotes	Newman
T21254	16135-16144	NN	denotes	post-test
T21253	16120-16121	DT	denotes	a
T21252	16116-16119	CC	denotes	and
T21251	16105-16106	HYPH	denotes	-
T21250	16106-16109	NN	denotes	way
T21249	16102-16105	CD	denotes	one
T21248	16110-16115	NN	denotes	ANOVA
T21247	16100-16101	DT	denotes	a
T21246	16097-16099	IN	denotes	by
T21245	16083-16087	VBD	denotes	were
T21244	16077-16082	NN	denotes	Lepob
T21243	16073-16076	CC	denotes	and
T21242	16071-16072	SYM	denotes	-
T21241	16070-16071	HYPH	denotes	/
T21240	16069-16070	SYM	denotes	-
T21239	16068-16069	CD	denotes	1
T21238	16067-16068	HYPH	denotes	-
T21237	16064-16067	NN	denotes	PAI
T21236	16062-16064	,	denotes	,
T21235	16060-16062	NN	denotes	B6
T21234	16055-16059	IN	denotes	from
T21233	16088-16096	VBN	denotes	compared
T21232	16048-16054	NNS	denotes	values
T21231	16044-16047	CC	denotes	and
T21230	16042-16044	,	denotes	,
T21229	16037-16038	HYPH	denotes	-
T21228	16036-16037	NN	denotes	t
T21227	16038-16042	NN	denotes	test
T21226	16034-16035	DT	denotes	a
T21225	16029-16033	IN	denotes	with
T21224	16015-16019	VBD	denotes	were
T21223	16003-16014	NNS	denotes	littermates
T21222	16001-16002	SYM	denotes	-
T21221	16000-16001	HYPH	denotes	/
T21220	15999-16000	SYM	denotes	-
T21219	15996-15999	NN	denotes	Plg
T21218	15992-15995	CC	denotes	and
T21217	15989-15991	NN	denotes	WT
T21216	15984-15988	IN	denotes	from
T21215	15980-15983	CC	denotes	and
T21214	15977-15978	HYPH	denotes	/
T21213	15978-15979	NN	denotes	J
T21212	15976-15977	NN	denotes	A
T21211	15972-15975	CC	denotes	and
T21210	15969-15971	NN	denotes	B6
T21209	15964-15968	IN	denotes	from
T21208	15957-15963	NNS	denotes	values
T21207	15955-15957	,	denotes	,
T21206	15944-15955	NNS	denotes	differences
T21205	15932-15943	JJ	denotes	statistical
T21204	16020-16028	VBN	denotes	compared
T21203	15922-15931	VB	denotes	determine
T21202	15919-15921	TO	denotes	To
T21201	15918-16145	sentence	denotes	To determine statistical differences, values from B6 and A/J and from WT and Plg-/- littermates were compared with a t-test, and values from B6, PAI-1-/- and Lepob were compared by a one-way ANOVA and a Newman-Keuls post-test.
T21200	15917-15918	.	denotes	.
T21199	15916-15917	-RRB-	denotes	)
T21198	15909-15916	NNS	denotes	seconds
T21197	15908-15909	-LRB-	denotes	(
T21196	15892-15902	NN	denotes	Rebleeding
T21195	15890-15892	:	denotes	:
T21194	15903-15907	NN	denotes	time
T21193	15887-15889	,	denotes	,
T21192	15886-15887	NN	denotes	C
T21191	15889-15890	NN	denotes	D
T21190	15880-15885	NN	denotes	Panel
T21189	15876-15879	CC	denotes	and
T21188	15874-15875	-RRB-	denotes	)
T21187	15867-15874	NNS	denotes	seconds
T21186	15866-15867	-LRB-	denotes	(
T21185	15852-15860	NN	denotes	Bleeding
T21184	15850-15852	:	denotes	:
T21183	15861-15865	NN	denotes	time
T21182	15847-15849	,	denotes	,
T21181	15846-15847	NN	denotes	A
T21180	15849-15850	NN	denotes	B
T21179	15840-15845	NN	denotes	Panel
T21178	15839-15918	sentence	denotes	Panel A, B: Bleeding time (seconds) and Panel C, D: Rebleeding time (seconds).
T21177	15838-15839	.	denotes	.
T21176	15832-15833	SYM	denotes	-
T21175	15831-15832	HYPH	denotes	/
T21174	15830-15831	SYM	denotes	-
T21173	15829-15830	CD	denotes	1
T21172	15828-15829	HYPH	denotes	-
T21171	15825-15828	NN	denotes	PAI
T21170	15821-15824	CC	denotes	and
T21169	15819-15820	SYM	denotes	-
T21168	15818-15819	HYPH	denotes	/
T21167	15817-15818	SYM	denotes	-
T21166	15814-15817	NN	denotes	Plg
T21165	15812-15814	,	denotes	,
T21164	15807-15812	NNP	denotes	Lepob
T21163	15805-15807	,	denotes	,
T21162	15803-15804	HYPH	denotes	/
T21161	15804-15805	NN	denotes	J
T21160	15802-15803	NN	denotes	A
T21159	15800-15802	,	denotes	,
T21158	15834-15838	NNS	denotes	mice
T21157	15798-15800	NN	denotes	B6
T21156	15795-15797	IN	denotes	in
T21155	15779-15789	NN	denotes	rebleeding
T20845	14391-14392	DT	denotes	a
T20844	14381-14390	VBZ	denotes	indicates
T20843	14374-14380	NN	denotes	Symbol
T20842	14373-14470	sentence	denotes	Symbol indicates a significant difference (**P < 0.01) between B6 mice determined with a t-test.
T20841	14372-14373	.	denotes	.
T20840	14364-14372	NN	denotes	genotype
T20839	14360-14363	IN	denotes	per
T20838	14355-14359	NNS	denotes	mice
T20837	14351-14352	HYPH	denotes	–
T20836	14352-14354	CD	denotes	17
T20835	14349-14351	CD	denotes	14
T20834	14346-14348	IN	denotes	of
T20833	14340-14341	SYM	denotes	±
T20832	14342-14345	NN	denotes	SEM
T20831	14335-14339	NN	denotes	mean
T20830	14333-14335	,	denotes	,
T20829	14329-14333	NN	denotes	time
T20828	14319-14328	NN	denotes	occlusion
T20827	14310-14318	JJ	denotes	Arterial
T20826	14308-14310	:	denotes	:
T20825	14307-14308	NN	denotes	C
T20824	14301-14306	NN	denotes	Panel
T20823	14300-14373	sentence	denotes	Panel C: Arterial occlusion time, mean ± SEM of 14–17 mice per genotype.
T20822	14299-14300	.	denotes	.
T20821	14295-14299	NNS	denotes	mice
T20820	14292-14293	HYPH	denotes	/
T20819	14293-14294	NN	denotes	J
T20818	14291-14292	NN	denotes	A
T20817	14289-14291	:	denotes	:
T20816	14288-14289	NN	denotes	B
T20815	14282-14287	NN	denotes	Panel
T20814	14280-14282	,	denotes	,
T20813	14276-14280	NNS	denotes	mice
T20812	14273-14275	NN	denotes	B6
T20811	14271-14273	:	denotes	:
T20810	14270-14271	NN	denotes	A
T20809	14264-14269	NN	denotes	Panel
T20808	14263-14300	sentence	denotes	Panel A: B6 mice, Panel B: A/J mice.
T20807	14262-14263	.	denotes	.
T20806	14255-14262	NN	denotes	carotid
T20805	14251-14254	DT	denotes	the
T20804	14248-14250	IN	denotes	to
T20803	14236-14247	NN	denotes	application
T20802	14227-14235	NN	denotes	chloride
T20801	14220-14226	JJ	denotes	ferric
T20800	14217-14219	IN	denotes	of
T20799	14208-14216	NN	denotes	duration
T20798	14199-14207	VBP	denotes	indicate
T20797	14192-14198	NNS	denotes	arrows
T20796	14188-14191	JJ	denotes	Red
T20795	14187-14263	sentence	denotes	Red arrows indicate duration of ferric chloride application to the carotid.
T20794	14186-14187	.	denotes	.
T20793	14178-14186	NN	denotes	genotype
T20792	14173-14177	DT	denotes	each
T20791	14168-14172	IN	denotes	from
T20790	14151-14160	NN	denotes	occlusion
T20789	14161-14167	NNS	denotes	curves
T20788	14136-14150	JJ	denotes	representative
T20787	14130-14131	NN	denotes	B
T20786	14126-14129	CC	denotes	and
T20785	14132-14135	VBP	denotes	are
T20784	14124-14125	NN	denotes	A
T20783	14117-14123	NNS	denotes	Panels
T20782	14116-14187	sentence	denotes	Panels A and B are representative occlusion curves from each genotype.
T20781	14115-14116	.	denotes	.
T20780	14108-14109	HYPH	denotes	/
T20779	14109-14110	NN	denotes	J
T20778	14107-14108	NN	denotes	A
T20777	14103-14106	CC	denotes	and
T20776	14111-14115	NNS	denotes	mice
T20775	14100-14102	NN	denotes	B6
T20774	14097-14099	IN	denotes	in
T20773	14092-14096	NN	denotes	time
T20772	14082-14091	NN	denotes	occlusion
T20771	14073-14081	JJ	denotes	Arterial
T20071	35485-35493	RB	denotes	upstream
T20070	35519-35521	VB	denotes	be
T20069	35479-35484	NNS	denotes	genes
T20068	35468-35478	JJ	denotes	regulatory
T20067	35464-35467	CC	denotes	but
T20066	35462-35464	,	denotes	,
T20065	35461-35462	-RRB-	denotes	]
T20064	35459-35461	CD	denotes	51
T20063	35458-35459	-LRB-	denotes	[
T20062	35446-35457	NNS	denotes	differences
T20061	35443-35445	DT	denotes	no
T20060	35429-35433	VBP	denotes	have
T20059	35421-35422	HYPH	denotes	/
T20058	35422-35423	NN	denotes	J
T20057	35420-35421	NN	denotes	A
T20056	35416-35419	CC	denotes	and
T20055	35424-35428	NNS	denotes	mice
T20054	35413-35415	NN	denotes	B6
T20053	35410-35412	IN	denotes	in
T20052	35392-35393	HYPH	denotes	-
T20051	35393-35404	NN	denotes	antiplasmin
T20050	35390-35392	NN	denotes	α2
T20049	35405-35409	NN	denotes	gene
T20048	35386-35389	DT	denotes	the
T20047	35383-35385	CC	denotes	or
T20046	35376-35377	CD	denotes	1
T20045	35375-35376	HYPH	denotes	-
T20044	35372-35375	NN	denotes	PAI
T20043	35378-35382	NN	denotes	gene
T20042	35368-35371	DT	denotes	the
T20041	35364-35367	IN	denotes	for
T20040	35434-35442	VBN	denotes	reported
T20039	35345-35349	NN	denotes	pair
T20038	35350-35358	NN	denotes	sequence
T20037	35340-35344	NN	denotes	base
T20036	35359-35363	NNS	denotes	data
T20035	35336-35339	NN	denotes	DNA
T20034	35335-35532	sentence	denotes	DNA base pair sequence data for the PAI-1 gene or the α2-antiplasmin gene in B6 and A/J mice have reported no differences [51], but regulatory genes upstream of the coding region may be important.
T20033	35334-35335	.	denotes	.
T20032	35329-35334	NNS	denotes	genes
T20031	35321-35328	JJ	denotes	unknown
T20030	35318-35320	IN	denotes	to
T20029	35309-35317	NN	denotes	addition
T20028	35306-35308	IN	denotes	in
T20027	35303-35305	CD	denotes	17
T20026	35292-35302	NN	denotes	chromosome
T20025	35289-35291	IN	denotes	on
T20024	35282-35288	VBP	denotes	reside
T20023	35277-35281	WDT	denotes	that
T20022	35268-35276	NN	denotes	proteins
T20021	35261-35267	NN	denotes	matrix
T20020	35257-35260	CC	denotes	and
T20019	35247-35256	NNS	denotes	proteases
T20018	35241-35246	JJ	denotes	other
T20017	35237-35240	IN	denotes	for
T20016	35231-35236	NNS	denotes	genes
T20015	35227-35230	VBP	denotes	are
T20014	35221-35226	EX	denotes	There
T20013	35220-35335	sentence	denotes	There are genes for other proteases and matrix proteins that reside on chromosome 17 in addition to unknown genes.
T20012	35219-35220	.	denotes	.
T20011	35216-35219	NN	denotes	Plg
T20010	35212-35215	RB	denotes	not
T20009	35205-35208	NN	denotes	QTL
T20008	35201-35204	DT	denotes	the
T20007	35209-35211	VBZ	denotes	is
T20006	35196-35200	IN	denotes	that
T20005	35185-35195	VBG	denotes	indicating
T20004	35183-35185	,	denotes	,
T20003	35179-35183	NNS	denotes	mice
T20002	35176-35178	NN	denotes	B6
T20001	35171-35175	IN	denotes	from
T20000	35164-35170	NNS	denotes	values
T19999	35161-35163	IN	denotes	to
T19998	35153-35160	JJ	denotes	similar
T19997	35132-35140	JJ	denotes	congenic
T19996	35141-35147	NN	denotes	strain
T19995	35127-35131	DT	denotes	this
T19994	35124-35126	IN	denotes	in
T19993	35113-35123	NN	denotes	rebleeding
T19992	35109-35112	CC	denotes	and
T19991	35100-35108	NN	denotes	bleeding
T19990	35096-35099	IN	denotes	for
T19989	35148-35152	VBD	denotes	were
T19988	35089-35095	NNS	denotes	Values
T19987	35088-35220	sentence	denotes	Values for bleeding and rebleeding in this congenic strain were similar to values from B6 mice, indicating that the QTL is not Plg.
T19986	35087-35088	.	denotes	.
T19985	35073-35081	NN	denotes	bleeding
T19984	35082-35087	NN	denotes	assay
T19983	35069-35072	DT	denotes	the
T19982	35066-35068	IN	denotes	in
T19981	35055-35058	VBD	denotes	was
T19980	35046-35049	NN	denotes	Plg
T19979	35050-35054	NN	denotes	gene
T19978	35042-35045	DT	denotes	the
T19977	35033-35041	VBZ	denotes	includes
T19976	35028-35032	WDT	denotes	that
T19975	35025-35027	CD	denotes	17
T19974	35014-35024	NN	denotes	chromosome
T19973	35011-35012	HYPH	denotes	/
T19972	35012-35013	NN	denotes	J
T19971	35010-35011	NN	denotes	A
T19970	35007-35009	IN	denotes	of
T19969	35005-35006	-RRB-	denotes	)
T19968	35001-35005	NNS	denotes	mice
T19967	34998-35000	NN	denotes	B6
T19966	34993-34997	IN	denotes	from
T19965	34979-34989	NN	denotes	background
T19964	34990-34992	VBZ	denotes	is
T19963	34975-34978	CC	denotes	and
T19962	34961-34970	VBG	denotes	remaining
T19961	34971-34974	NN	denotes	Chr
T19960	34957-34960	DT	denotes	the
T19959	34953-34956	CC	denotes	and
T19958	34950-34951	HYPH	denotes	/
T19957	34951-34952	NN	denotes	J
T19956	34949-34950	NN	denotes	A
T19955	34944-34948	IN	denotes	from
T19954	34927-34936	JJ	denotes	homosomic
T19953	34937-34943	NN	denotes	region
T19952	34925-34926	DT	denotes	a
T19951	34921-34924	IN	denotes	for
T19950	34912-34920	JJ	denotes	specific
T19949	34911-34912	-LRB-	denotes	(
T19948	35059-35065	VBN	denotes	tested
T19947	34895-34903	JJ	denotes	congenic
T19946	34904-34910	NN	denotes	strain
T19945	34893-34894	DT	denotes	A
T19944	34892-35088	sentence	denotes	A congenic strain (specific for a homosomic region from A/J and the remaining Chr and background is from B6 mice) of A/J chromosome 17 that includes the Plg gene was tested in the bleeding assay.
T19943	34891-34892	.	denotes	.
T19942	34869-34879	JJ	denotes	functional
T19941	34880-34891	NNS	denotes	differences
T19940	34860-34868	JJ	denotes	possible
T19939	34848-34851	RB	denotes	not
T19938	34842-34847	MD	denotes	would
T19937	34837-34841	DT	denotes	this
T19936	34835-34837	,	denotes	,
T19935	34826-34835	NN	denotes	structure
T19934	34822-34825	NN	denotes	Plg
T19933	34819-34821	IN	denotes	in
T19932	34807-34818	NNS	denotes	differences
T19931	34852-34859	VB	denotes	exclude
T19930	34796-34799	RB	denotes	not
T19929	34792-34795	VBD	denotes	did
T19928	34789-34791	PRP	denotes	we
T19927	34800-34806	VB	denotes	detect
T19926	34780-34788	IN	denotes	Although
T19925	34779-34892	sentence	denotes	Although we did not detect differences in Plg structure, this would not exclude possible functional differences.
T19924	34778-34779	.	denotes	.
T19923	34774-34778	NNS	denotes	mice
T19922	34771-34773	NN	denotes	B6
T19921	34768-34770	IN	denotes	to
T19920	34759-34767	VBN	denotes	compared
T19919	34754-34758	NNS	denotes	mice
T19918	34751-34752	HYPH	denotes	/
T19917	34752-34753	NN	denotes	J
T19916	34750-34751	NN	denotes	A
T19915	34747-34749	IN	denotes	in
T19914	34733-34736	VBD	denotes	was
T19913	34737-34746	VBN	denotes	increased
T19912	34719-34732	NN	denotes	concentration
T19911	34715-34718	NN	denotes	Plg
T19910	34714-34779	sentence	denotes	Plg concentration was increased in A/J mice compared to B6 mice.
T19909	34713-34714	.	denotes	.
T19908	34712-34713	-RRB-	denotes	]
T19907	34710-34712	CD	denotes	40
T19906	34709-34710	-LRB-	denotes	[
T19905	34701-34702	HYPH	denotes	/
T19904	34702-34703	NN	denotes	J
T19903	34700-34701	NN	denotes	A
T19902	34696-34699	CC	denotes	and
T19901	34704-34708	NNS	denotes	mice
T19900	34693-34695	NN	denotes	B6
T19899	34689-34692	IN	denotes	for
T19898	34675-34679	VBN	denotes	been
T19897	34670-34674	VBP	denotes	have
T19896	34661-34664	NN	denotes	Plg
T19895	34655-34660	NN	denotes	mouse
T19894	34665-34669	NN	denotes	gene
T19893	34651-34654	DT	denotes	the
T19892	34648-34650	IN	denotes	of
T19891	34680-34688	VBN	denotes	reported
T19890	34634-34641	JJ	denotes	allelic
T19889	34642-34647	NNS	denotes	forms
T19888	34630-34633	CD	denotes	Two
T19887	34629-34714	sentence	denotes	Two allelic forms of the mouse Plg gene have been reported for B6 and A/J mice [40].
T19886	34628-34629	.	denotes	.
T20483	36586-36588	IN	denotes	of
T20482	36576-36585	NN	denotes	screening
T20481	36572-36575	CC	denotes	and
T20480	36570-36572	,	denotes	,
T20479	36565-36570	NN	denotes	study
T20478	36560-36564	DT	denotes	this
T20477	36557-36559	IN	denotes	in
T20476	36547-36556	VBN	denotes	described
T20475	36541-36546	DT	denotes	those
T20474	36538-36540	IN	denotes	as
T20473	36533-36537	JJ	denotes	such
T20472	36531-36533	,	denotes	,
T20471	36517-36523	NN	denotes	parent
T20470	36524-36531	NNS	denotes	strains
T20469	36513-36516	DT	denotes	the
T20468	36510-36512	IN	denotes	in
T20467	36498-36509	NNS	denotes	differences
T20466	36495-36497	IN	denotes	of
T20465	36597-36599	VBZ	denotes	is
T20464	36480-36494	NN	denotes	Identification
T20463	36479-36677	sentence	denotes	Identification of differences in the parent strains, such as those described in this study, and screening of the CSS is a first-step in the discovery of new genetic determinants of thrombotic risk.
T20462	36478-36479	.	denotes	.
T20461	36458-36471	JJ	denotes	extracellular
T20460	36472-36478	NN	denotes	matrix
T20459	36451-36457	NN	denotes	vessel
T20458	36447-36450	CC	denotes	and
T20457	36435-36436	HYPH	denotes	/
T20456	36427-36435	NN	denotes	bleeding
T20455	36436-36446	NN	denotes	rebleeding
T20454	36422-36426	NN	denotes	tail
T20453	36420-36422	,	denotes	,
T20452	36410-36420	NN	denotes	thrombosis
T20451	36401-36409	JJ	denotes	arterial
T20450	36398-36400	IN	denotes	to
T20449	36390-36397	VBN	denotes	related
T20448	36383-36389	NNS	denotes	traits
T20447	36379-36382	DT	denotes	the
T20446	36375-36378	IN	denotes	for
T20445	36363-36374	JJ	denotes	responsible
T20444	36357-36362	NNS	denotes	genes
T20443	36353-36356	DT	denotes	the
T20442	36344-36352	VB	denotes	identify
T20441	36341-36343	TO	denotes	to
T20440	36333-36335	VB	denotes	be
T20439	36329-36332	MD	denotes	can
T20438	36315-36322	JJ	denotes	unknown
T20437	36312-36314	CC	denotes	or
T20436	36323-36328	NNS	denotes	genes
T20435	36306-36311	JJ	denotes	novel
T20434	36336-36340	VBN	denotes	used
T20433	36301-36305	IN	denotes	that
T20432	36279-36282	NN	denotes	CSS
T19885	34616-34617	HYPH	denotes	-
T19884	34617-34628	NN	denotes	antiplasmin
T19883	34614-34616	NN	denotes	α2
T19882	34610-34613	CC	denotes	and
T19881	34608-34610	,	denotes	,
T19880	34607-34608	CD	denotes	1
T19879	34606-34607	HYPH	denotes	-
T19878	34603-34606	NN	denotes	PAI
T19877	34601-34603	,	denotes	,
T19876	34598-34601	NN	denotes	Plg
T19875	34589-34597	JJ	denotes	variable
T19874	34569-34579	NN	denotes	rebleeding
T19873	34580-34584	NN	denotes	time
T19872	34560-34568	JJ	denotes	elevated
T19871	34555-34559	IN	denotes	with
T19870	34541-34546	CD	denotes	three
T19869	34547-34554	NNS	denotes	strains
T19868	34537-34540	DT	denotes	the
T19867	34533-34536	CC	denotes	and
T19866	34525-34526	HYPH	denotes	/
T19865	34526-34527	NN	denotes	J
T19864	34524-34525	NN	denotes	A
T19863	34528-34532	NNS	denotes	mice
T19862	34520-34523	DT	denotes	the
T19861	34518-34520	,	denotes	,
T19860	34511-34513	NN	denotes	B6
T19859	34514-34518	NNS	denotes	mice
T19858	34507-34510	DT	denotes	the
T19857	34504-34506	IN	denotes	to
T19856	34585-34588	VBD	denotes	had
T19741	33907-33908	.	denotes	.
T19740	33900-33901	HYPH	denotes	/
T19739	33901-33902	NN	denotes	J
T19738	33899-33900	NN	denotes	A
T19737	33903-33907	NNS	denotes	mice
T19736	33895-33898	DT	denotes	the
T19735	33892-33894	IN	denotes	in
T19734	33887-33891	NN	denotes	tail
T19733	33883-33886	DT	denotes	the
T19732	33880-33882	IN	denotes	of
T19731	33863-33871	NN	denotes	collagen
T19730	33872-33879	NN	denotes	content
T19729	33859-33862	DT	denotes	the
T19728	33856-33858	IN	denotes	in
T19727	33845-33855	NN	denotes	difference
T19726	33843-33844	DT	denotes	a
T19725	33828-33832	NN	denotes	tail
T19724	33824-33827	DT	denotes	the
T19723	33821-33823	IN	denotes	of
T19722	33833-33842	VBD	denotes	indicated
T19721	33812-33820	NN	denotes	analysis
T19720	33799-33811	JJ	denotes	Morphometric
T19719	33798-33908	sentence	denotes	Morphometric analysis of the tail indicated a difference in the collagen content of the tail in the A/J mice.
T19718	33797-33798	.	denotes	.
T19717	33781-33791	NN	denotes	rebleeding
T19716	33778-33780	CC	denotes	or
T19715	33769-33777	NN	denotes	bleeding
T19714	33792-33797	NNS	denotes	times
T19713	33764-33768	NN	denotes	tail
T19712	33760-33763	CC	denotes	and
T19711	33751-33759	NN	denotes	pressure
T19710	33745-33750	NN	denotes	blood
T19709	33737-33744	IN	denotes	between
T19708	33722-33736	NN	denotes	correspondence
T19707	33719-33721	DT	denotes	no
T19706	33716-33718	VBZ	denotes	is
T19705	33710-33715	EX	denotes	there
T19704	33706-33709	CC	denotes	but
T19703	33704-33706	,	denotes	,
T19702	33690-33695	NN	denotes	blood
T19701	33696-33704	NN	denotes	pressure
T19700	33682-33689	VBN	denotes	reduced
T19699	33672-33676	RB	denotes	also
T19698	33677-33681	VBP	denotes	have
T19697	33665-33666	-RRB-	denotes	]
T19695	33660-33662	CD	denotes	38
T19694	33663-33665	CD	denotes	39
T19693	33659-33660	-LRB-	denotes	[
T19692	33653-33658	NN	denotes	Lepob
T19691	33649-33652	CC	denotes	and
T19690	33647-33648	-RRB-	denotes	]
T19689	33645-33647	CD	denotes	37
T19688	33644-33645	-LRB-	denotes	[
T19687	33642-33643	SYM	denotes	-
T19686	33641-33642	HYPH	denotes	/
T19685	33640-33641	SYM	denotes	-
T19684	33667-33671	NNS	denotes	mice
T19683	33637-33640	NN	denotes	uPA
T19682	33633-33636	CC	denotes	and
T19681	33631-33633	,	denotes	,
T19680	33620-33631	NNS	denotes	littermates
T19679	33617-33619	JJ	denotes	WT
T19678	33614-33616	IN	denotes	to
T19677	33605-33613	VBN	denotes	compared
T19676	33600-33604	WRB	denotes	when
T19675	33585-33590	NN	denotes	blood
T19674	33591-33599	NN	denotes	pressure
T19673	33577-33584	VBN	denotes	reduced
T19672	33572-33576	VBP	denotes	have
T19671	33567-33571	NNS	denotes	mice
T19670	33561-33566	DT	denotes	these
T19669	33557-33560	CC	denotes	and
T19668	33555-33557	,	denotes	,
T19667	33554-33555	-RRB-	denotes	)
T19666	33547-33554	NNS	denotes	results
T19665	33535-33546	JJ	denotes	unpublished
T19664	33533-33535	,	denotes	,
T19663	33529-33533	NNP	denotes	Plow
T19662	33526-33528	NNP	denotes	E.
T19661	33522-33525	CC	denotes	and
T19660	33520-33522	,	denotes	,
T19659	33516-33520	NNP	denotes	Plow
T19658	33515-33516	HYPH	denotes	-
T19657	33509-33515	NNP	denotes	Hoover
T19656	33506-33508	NNP	denotes	J.
T19655	33504-33506	,	denotes	,
T19654	33497-33504	NNP	denotes	Hellard
T19653	33494-33496	NNP	denotes	D.
T19652	33493-33494	-LRB-	denotes	(
T19651	33486-33487	SYM	denotes	-
T19650	33485-33486	HYPH	denotes	/
T19649	33484-33485	SYM	denotes	-
T19648	33481-33484	NN	denotes	Plg
T19647	33488-33492	NNS	denotes	mice
T19646	33477-33480	DT	denotes	the
T19645	33474-33476	IN	denotes	in
T19644	33461-33464	VBD	denotes	was
T19643	33465-33473	VBN	denotes	measured
T19642	33452-33460	NN	denotes	pressure
T19641	33446-33451	NN	denotes	Blood
T19640	33445-33798	sentence	denotes	Blood pressure was measured in the Plg-/- mice (D. Hellard, J. Hoover-Plow, and E. Plow, unpublished results), and these mice have reduced blood pressure when compared to WT littermates, and uPA-/- [37] and Lepob [38,39] mice also have reduced blood pressure, but there is no correspondence between blood pressure and tail bleeding or rebleeding times.
T19639	33444-33445	.	denotes	.
T19638	33437-33439	NN	denotes	B6
T19637	33440-33444	NNS	denotes	mice
T19636	33433-33436	DT	denotes	the
T19635	33430-33432	IN	denotes	to
T19634	33421-33429	VBN	denotes	compared
T19633	33410-33420	NN	denotes	difference
T19632	33407-33409	DT	denotes	no
T19631	33404-33406	CC	denotes	or
T19630	33389-33394	NN	denotes	blood
T19629	33379-33388	VBN	denotes	decreased
T19628	33395-33403	NN	denotes	pressure
T19627	33372-33378	CC	denotes	either
T19626	33358-33362	VBP	denotes	have
T19625	33351-33352	-RRB-	denotes	]
T19624	33349-33351	CD	denotes	36
T19623	33348-33349	SYM	denotes	-
T19622	33346-33348	CD	denotes	33
T19621	33345-33346	-LRB-	denotes	[
T19620	33353-33357	NNS	denotes	mice
T19619	33342-33343	HYPH	denotes	/
T19618	33343-33344	NN	denotes	J
T19617	33341-33342	NN	denotes	A
T19616	33338-33340	IN	denotes	of
T19615	33363-33371	VBN	denotes	reported
T19614	33330-33337	NNS	denotes	Studies
T19613	33329-33445	sentence	denotes	Studies of A/J [33-36] mice have reported either decreased blood pressure or no difference compared to the B6 mice.
T19612	33328-33329	.	denotes	.
T19611	33324-33328	NN	denotes	case
T19610	33320-33323	DT	denotes	the
T19609	33316-33319	RB	denotes	not
T19608	33308-33312	DT	denotes	this
T19607	33313-33315	VBZ	denotes	is
T19606	33303-33307	IN	denotes	that
T19605	33287-33294	NNS	denotes	studies
T19604	33279-33286	JJ	denotes	several
T19603	33277-33279	,	denotes	,
T19602	33264-33272	NN	denotes	bleeding
T19601	33259-33263	NN	denotes	tail
T19600	33273-33277	NN	denotes	time
T19599	33250-33258	VBN	denotes	elevated
T19598	33245-33249	IN	denotes	with
T19597	33240-33244	NNS	denotes	mice
T19596	33237-33239	IN	denotes	in
T19595	33230-33236	JJR	denotes	higher
T19594	33295-33302	VBP	denotes	suggest
T19593	33215-33226	RB	denotes	conceivably
T19592	33209-33214	MD	denotes	could
T19591	33200-33208	NN	denotes	pressure
T19590	33194-33199	NN	denotes	blood
T19589	33227-33229	VB	denotes	be
T19588	33188-33193	IN	denotes	While
T19587	33187-33329	sentence	denotes	While blood pressure could conceivably be higher in mice with elevated tail bleeding time, several studies suggest that this is not the case.
T19586	33186-33187	.	denotes	.
T19585	33164-33175	RB	denotes	genetically
T19584	33161-33163	VBZ	denotes	is
T19583	33156-33160	NN	denotes	time
T19582	33145-33155	NN	denotes	rebleeding
T19581	33140-33144	NN	denotes	tail
T19580	33176-33186	VBN	denotes	determined
T19579	33135-33139	IN	denotes	that
T19578	33130-33134	RB	denotes	also
T19577	33126-33129	CC	denotes	but
T19576	33124-33126	,	denotes	,
T19575	33114-33124	NN	denotes	background
T19574	33111-33113	IN	denotes	by
T19573	33088-33099	RB	denotes	genetically
T19572	33083-33087	NN	denotes	time
T19571	33074-33082	NN	denotes	bleeding
T19570	33071-33073	VBZ	denotes	is
T19569	33066-33070	RB	denotes	only
T19568	33062-33065	RB	denotes	not
T19567	33100-33110	VBN	denotes	determined
T19566	33057-33061	IN	denotes	that
T19565	33043-33048	NN	denotes	study
T19564	33038-33042	DT	denotes	this
T19563	33035-33037	IN	denotes	of
T19562	33049-33056	VBP	denotes	suggest
T19561	33027-33034	NNS	denotes	results
T19560	33023-33026	DT	denotes	The
T19559	33022-33187	sentence	denotes	The results of this study suggest that not only is bleeding time genetically determined by background, but also that tail rebleeding time is genetically determined.
T19558	33021-33022	.	denotes	.
T19557	33020-33021	-RRB-	denotes	)
T19556	33013-33020	NNS	denotes	results
T20161	35966-35970	WDT	denotes	that
T20160	35950-35954	VBD	denotes	were
T20159	35945-35949	NNS	denotes	mice
T20158	35942-35943	HYPH	denotes	/
T20157	35943-35944	NN	denotes	J
T20156	35941-35942	NN	denotes	A
T20155	35936-35940	IN	denotes	from
T20154	35955-35965	VBN	denotes	identified
T20153	35924-35935	NNS	denotes	chromosomes
T20152	35918-35923	CD	denotes	Three
T20151	35917-35999	sentence	denotes	Three chromosomes from A/J mice were identified that had QTL for rebleeding time.
T20150	35916-35917	.	denotes	.
T20149	35897-35905	NN	denotes	collagen
T20148	35890-35896	NN	denotes	vessel
T20147	35886-35889	CC	denotes	and
T20146	35906-35916	NN	denotes	deposition
T20145	35879-35885	NN	denotes	tissue
T20144	35875-35878	CC	denotes	and
T20143	35873-35875	,	denotes	,
T20142	35865-35873	NN	denotes	function
T20141	35853-35864	NN	denotes	plasminogen
T20140	35851-35853	,	denotes	,
T20139	35837-35845	NN	denotes	bleeding
T20138	35832-35836	NN	denotes	tail
T20137	35846-35851	NN	denotes	assay
T20136	35830-35831	DT	denotes	a
T20135	35827-35829	IN	denotes	in
T20134	35822-35826	NN	denotes	time
T20133	35811-35821	NN	denotes	rebleeding
T20132	35809-35811	,	denotes	,
T20131	35797-35803	NN	denotes	injury
T20130	35788-35796	JJ	denotes	vascular
T20129	35782-35787	NN	denotes	FeCl3
T20128	35804-35809	NN	denotes	model
T20127	35780-35781	DT	denotes	a
T20126	35777-35779	IN	denotes	in
T20125	35767-35776	NN	denotes	formation
T20124	35756-35766	NN	denotes	thrombosis
T20123	35747-35755	JJ	denotes	arterial
T20122	35744-35746	IN	denotes	in
T20121	35742-35744	,	denotes	,
T20120	35740-35741	HYPH	denotes	/
T20119	35741-35742	NN	denotes	J
T20118	35739-35740	NN	denotes	A
T20117	35735-35738	CC	denotes	and
T20116	35732-35734	NN	denotes	B6
T20115	35730-35732	,	denotes	,
T20114	35726-35730	NNS	denotes	mice
T20113	35723-35725	IN	denotes	of
T20112	35708-35714	JJ	denotes	inbred
T20111	35715-35722	NNS	denotes	strains
T20110	35704-35707	CD	denotes	two
T20109	35701-35703	IN	denotes	in
T20108	35689-35700	NNS	denotes	differences
T20107	35682-35688	JJ	denotes	marked
T20106	35668-35673	NN	denotes	study
T20105	35663-35667	DT	denotes	this
T20104	35661-35663	,	denotes	,
T20103	35654-35661	NN	denotes	summary
T20102	35674-35681	VBZ	denotes	reports
T20101	35651-35653	IN	denotes	In
T20100	35650-35917	sentence	denotes	In summary, this study reports marked differences in two inbred strains of mice, B6 and A/J, in arterial thrombosis formation in a FeCl3 vascular injury model, rebleeding time in a tail bleeding assay, plasminogen function, and tissue and vessel collagen deposition.
T20099	35649-35650	.	denotes	.
T20098	35641-35649	NN	denotes	function
T20097	35635-35640	PRP$	denotes	their
T20096	35628-35634	VB	denotes	modify
T20095	35625-35627	TO	denotes	to
T20094	35607-35613	NN	denotes	system
T20093	35603-35606	NN	denotes	Plg
T20092	35614-35624	NNS	denotes	components
T20091	35599-35602	DT	denotes	the
T20090	35594-35598	IN	denotes	with
T20089	35581-35584	MD	denotes	may
T20088	35567-35574	JJ	denotes	unknown
T20087	35564-35566	CC	denotes	or
T20086	35575-35580	NNS	denotes	genes
T20085	35558-35563	JJ	denotes	novel
T20084	35585-35593	VB	denotes	interact
T20083	35553-35557	IN	denotes	that
T20082	35545-35552	VBP	denotes	suggest
T20081	35537-35544	NNS	denotes	results
T20080	35533-35536	PRP$	denotes	Our
T20079	35532-35650	sentence	denotes	Our results suggest that novel or unknown genes may interact with the Plg system components to modify their function.
T20078	35531-35532	.	denotes	.
T20077	35522-35531	JJ	denotes	important
T20076	35515-35518	MD	denotes	may
T20075	35501-35507	VBG	denotes	coding
T20074	35508-35514	NN	denotes	region
T20073	35497-35500	DT	denotes	the
T20072	35494-35496	IN	denotes	of
T19555	33001-33012	JJ	denotes	unpublished
T19554	32999-33001	,	denotes	,
T19553	32995-32999	NNP	denotes	Hart
T19552	32992-32994	NNP	denotes	E.
T19551	32988-32991	CC	denotes	and
T19550	32986-32988	,	denotes	,
T19549	32978-32986	NNP	denotes	Shchurin
T19548	32975-32977	NNP	denotes	A.
T19547	32973-32975	,	denotes	,
T19546	32969-32973	NNP	denotes	Plow
T19545	32968-32969	HYPH	denotes	-
T19544	32962-32968	NNP	denotes	Hoover
T19542	32958-32959	-LRB-	denotes	(
T19541	32943-32946	CD	denotes	129
T19540	32942-32943	NN	denotes	%
T19539	32940-32942	CD	denotes	50
T19538	32939-32940	:	denotes	:
T19537	32937-32939	NN	denotes	B6
T19536	32936-32937	NN	denotes	%
T19535	32934-32936	CD	denotes	50
T19534	32947-32957	NN	denotes	background
T19533	32932-32933	DT	denotes	a
T19532	32929-32931	IN	denotes	in
T19531	32922-32923	SYM	denotes	-
T19530	32921-32922	HYPH	denotes	/
T19529	32920-32921	SYM	denotes	-
T19528	32924-32928	NNS	denotes	mice
T19527	32917-32920	NN	denotes	Plg
T19526	32913-32916	IN	denotes	for
T19413	32408-32416	NNP	denotes	Shchurin
T19412	32405-32407	NNP	denotes	A.
T19411	32403-32405	,	denotes	,
T19410	32399-32403	NNP	denotes	Plow
T19409	32398-32399	HYPH	denotes	-
T19408	32392-32398	NNP	denotes	Hoover
T19407	32389-32391	NNP	denotes	J.
T19406	32388-32389	-LRB-	denotes	(
T19405	32381-32382	SYM	denotes	-
T19404	32380-32381	HYPH	denotes	/
T19403	32379-32380	SYM	denotes	-
T19402	32376-32379	NN	denotes	Plg
T19401	32383-32387	NNS	denotes	mice
T19400	32372-32375	DT	denotes	the
T19399	32369-32371	IN	denotes	to
T19398	32361-32368	JJ	denotes	similar
T19397	32347-32355	NN	denotes	bleeding
T19396	32337-32346	VBN	denotes	increased
T19395	32356-32360	NN	denotes	time
T19394	32334-32336	DT	denotes	an
T19393	32330-32333	VBD	denotes	had
T19392	32323-32324	SYM	denotes	-
T19391	32322-32323	HYPH	denotes	/
T19390	32321-32322	SYM	denotes	-
T19389	32325-32329	NNS	denotes	mice
T19388	32318-32321	NN	denotes	uPA
T19387	32314-32317	CC	denotes	and
T19386	32312-32314	,	denotes	,
T19385	32297-32307	NN	denotes	rebleeding
T19384	32308-32312	NN	denotes	time
T19383	32287-32296	VBN	denotes	decreased
T19382	32281-32282	SYM	denotes	-
T19381	32280-32281	HYPH	denotes	/
T19380	32279-32280	SYM	denotes	-
T19379	32278-32279	CD	denotes	1
T19378	32277-32278	HYPH	denotes	-
T19377	32283-32286	VBD	denotes	had
T19376	32274-32277	NN	denotes	PAI
T19375	32272-32274	,	denotes	,
T19374	32259-32267	NN	denotes	bleeding
T19373	32268-32272	NN	denotes	time
T19372	32249-32258	VBN	denotes	increased
T19371	32238-32239	SYM	denotes	-
T19370	32237-32238	HYPH	denotes	/
T19369	32236-32237	SYM	denotes	-
T19368	32240-32244	NNS	denotes	mice
T19367	32233-32236	NN	denotes	Plg
T19366	32231-32233	,	denotes	,
T19365	32226-32231	NN	denotes	study
T19364	32222-32225	PRP$	denotes	our
T19363	32245-32248	VBD	denotes	had
T19362	32219-32221	IN	denotes	In
T19361	32218-32452	sentence	denotes	In our study, Plg-/- mice had increased bleeding time, PAI-1-/- had decreased rebleeding time, and uPA-/- mice had an increased bleeding time similar to the Plg-/- mice (J. Hoover-Plow, A. Shchurin, and E. Hart, unpublished results).
T19360	32217-32218	.	denotes	.
T19359	32213-32217	NNS	denotes	mice
T19358	32210-32212	NN	denotes	B6
T19357	32207-32209	IN	denotes	to
T19356	32198-32206	VBN	denotes	compared
T19355	32191-32197	JJR	denotes	higher
T19354	32187-32190	VBD	denotes	was
T19353	32182-32186	NN	denotes	time
T19352	32171-32181	NN	denotes	rebleeding
T19351	32167-32170	CC	denotes	but
T19350	32165-32167	,	denotes	,
T19349	32161-32165	NN	denotes	time
T19348	32152-32160	NN	denotes	bleeding
T19347	32149-32151	IN	denotes	in
T19346	32141-32148	NNS	denotes	changes
T19345	32132-32135	RB	denotes	not
T19344	32128-32131	VBD	denotes	did
T19343	32123-32127	NNS	denotes	mice
T19342	32120-32121	HYPH	denotes	/
T19341	32121-32122	NN	denotes	J
T19340	32119-32120	NN	denotes	A
T19339	32117-32119	,	denotes	,
T19338	32103-32111	NN	denotes	bleeding
T19337	32098-32102	NN	denotes	tail
T19336	32112-32117	NN	denotes	assay
T19335	32094-32097	DT	denotes	the
T19334	32136-32140	VB	denotes	have
T19333	32091-32093	IN	denotes	In
T19332	32090-32218	sentence	denotes	In the tail bleeding assay, A/J mice did not have changes in bleeding time, but rebleeding time was higher compared to B6 mice.
T19331	32089-32090	.	denotes	.
T19330	32081-32089	NN	denotes	thrombus
T19329	32079-32080	DT	denotes	a
T19328	32076-32078	IN	denotes	of
T19327	32066-32075	NN	denotes	stability
T19326	32062-32065	DT	denotes	the
T19325	32059-32061	IN	denotes	in
T19324	32054-32058	NN	denotes	role
T19323	32052-32053	DT	denotes	a
T19322	32043-32046	MD	denotes	may
T19321	32031-32042	NN	denotes	coagulation
T19320	32026-32030	IN	denotes	than
T19319	32020-32025	JJ	denotes	other
T19318	32047-32051	VB	denotes	play
T19317	32012-32019	NNS	denotes	factors
T19316	32004-32011	JJ	denotes	genetic
T19315	31981-31986	NN	denotes	mouse
T19314	31987-31994	NNS	denotes	strains
T19313	31973-31980	JJ	denotes	certain
T19312	31970-31972	IN	denotes	in
T19311	31961-31969	VBN	denotes	observed
T19310	31955-31960	NNS	denotes	times
T19309	31944-31954	NN	denotes	rebleeding
T19308	31941-31943	IN	denotes	in
T19307	31925-31931	JJ	denotes	marked
T19306	31932-31940	NN	denotes	increase
T19305	31921-31924	DT	denotes	the
T19304	31919-31921	,	denotes	,
T19303	31995-32003	VBZ	denotes	suggests
T19302	31912-31919	RB	denotes	Overall
T19301	31911-32090	sentence	denotes	Overall, the marked increase in rebleeding times observed in certain mouse strains suggests genetic factors other than coagulation may play a role in the stability of a thrombus.
T19300	31910-31911	.	denotes	.
T19299	31892-31900	NN	denotes	thrombus
T19298	31901-31910	NN	denotes	formation
T19297	31885-31891	JJ	denotes	normal
T19296	31877-31884	VB	denotes	promote
T19295	31874-31876	TO	denotes	to
T19294	31865-31873	NN	denotes	response
T19293	31856-31864	NN	denotes	platelet
T19292	31853-31855	IN	denotes	on
T19291	31843-31852	NN	denotes	influence
T19290	31840-31842	DT	denotes	an
T19289	31830-31833	MD	denotes	may
T19288	31826-31829	NN	denotes	uPA
T19287	31822-31825	CC	denotes	and
T19286	31818-31821	NN	denotes	Plg
T19285	31834-31839	VB	denotes	exert
T19284	31813-31817	IN	denotes	that
T19283	31797-31798	SYM	denotes	-
T19282	31796-31797	HYPH	denotes	/
T19281	31795-31796	SYM	denotes	-
T19280	31792-31795	NN	denotes	uPA
T19279	31788-31791	CC	denotes	and
T19278	31786-31787	SYM	denotes	-
T19277	31785-31786	HYPH	denotes	/
T19276	31784-31785	SYM	denotes	-
T19275	31799-31803	NNS	denotes	mice
T19274	31781-31784	NN	denotes	Plg
T19273	31778-31780	IN	denotes	in
T19272	31804-31812	VBZ	denotes	suggests
T19271	31764-31772	NN	denotes	bleeding
T19270	31754-31763	VBN	denotes	increased
T19269	31773-31777	NN	denotes	time
T19268	31750-31753	DT	denotes	the
T19267	31746-31749	CC	denotes	and
T19266	31741-31745	NN	denotes	time
T19265	31732-31740	NN	denotes	bleeding
T19264	31729-31731	IN	denotes	in
T19263	31713-31719	JJ	denotes	marked
T19262	31720-31728	NN	denotes	increase
T19261	31711-31712	DT	denotes	a
T19260	31697-31704	RB	denotes	clearly
T19259	31676-31684	NN	denotes	platelet
T19258	31685-31696	NN	denotes	aggregation
T19257	31668-31675	VBN	denotes	reduced
T19256	31663-31667	IN	denotes	with
T19255	31705-31710	VBZ	denotes	shows
T19254	31645-31651	NN	denotes	leptin
T19253	31652-31662	NN	denotes	deficiency
T19252	31641-31644	DT	denotes	The
T19251	31640-31911	sentence	denotes	The leptin deficiency with reduced platelet aggregation clearly shows a marked increase in bleeding time and the increased bleeding time in Plg-/- and uPA-/- mice suggests that Plg and uPA may exert an influence on platelet response to promote normal thrombus formation.
T19250	31639-31640	.	denotes	.
T19249	31635-31639	NN	denotes	time
T19248	31626-31634	NN	denotes	bleeding
T19247	31621-31625	NN	denotes	tail
T19246	31606-31610	VBP	denotes	have
T19245	31604-31605	-RRB-	denotes	]
T19244	31602-31604	CD	denotes	31
T19243	31601-31602	-LRB-	denotes	[
T19242	31599-31601	,	denotes	,
T19241	31598-31599	CD	denotes	4
T19240	31597-31598	HYPH	denotes	-
T19239	31589-31597	NN	denotes	receptor
T19238	31578-31579	HYPH	denotes	-
T19237	31579-31588	VBN	denotes	activated
T19236	31570-31578	NN	denotes	protease
T19235	31566-31569	CC	denotes	and
T19234	31564-31566	,	denotes	,
T19233	31563-31564	-RRB-	denotes	]
T19232	31561-31563	CD	denotes	30
T19231	31560-31561	-LRB-	denotes	[
T19230	31544-31556	NN	denotes	glycoprotein
T19229	31557-31559	NN	denotes	Ib
T19228	31535-31543	NN	denotes	platelet
T19855	34495-34503	VBN	denotes	compared
T19854	34490-34494	WRB	denotes	When
T19853	34489-34629	sentence	denotes	When compared to the B6 mice, the A/J mice and the three strains with elevated rebleeding time had variable Plg, PAI-1, and α2-antiplasmin.
T19852	34488-34489	.	denotes	.
T19851	34481-34482	HYPH	denotes	/
T19850	34482-34483	NN	denotes	J
T19849	34480-34481	NN	denotes	A
T19848	34484-34488	NNS	denotes	mice
T19847	34476-34479	DT	denotes	the
T19846	34473-34475	IN	denotes	in
T19845	34458-34467	NN	denotes	occlusion
T19844	34449-34457	JJ	denotes	arterial
T19843	34468-34472	NN	denotes	time
T19842	34441-34448	VBN	denotes	reduced
T19841	34437-34440	CC	denotes	and
T19840	34421-34431	NN	denotes	rebleeding
T19839	34411-34420	VBN	denotes	increased
T19838	34432-34436	NN	denotes	time
T19837	34407-34410	DT	denotes	the
T19836	34387-34397	NNS	denotes	components
T19835	34381-34386	DT	denotes	these
T19834	34378-34380	IN	denotes	of
T19833	34360-34363	DT	denotes	the
T19832	34364-34377	NN	denotes	concentration
T19831	34353-34359	RB	denotes	merely
T19830	34398-34406	VBZ	denotes	explains
T19829	34348-34352	IN	denotes	that
T19828	34341-34347	JJ	denotes	likely
T19827	34337-34340	RB	denotes	not
T19826	34334-34336	VBZ	denotes	is
T19825	34331-34333	PRP	denotes	It
T19824	34330-34489	sentence	denotes	It is not likely that merely the concentration of these components explains the increased rebleeding time and reduced arterial occlusion time in the A/J mice.
T19823	34329-34330	.	denotes	.
T19822	34326-34329	NNS	denotes	CSS
T19821	34322-34325	CC	denotes	and
T19820	34317-34321	NNS	denotes	mice
T19819	34314-34315	HYPH	denotes	/
T19818	34313-34314	NN	denotes	A
T19817	34315-34316	NN	denotes	J
T19816	34309-34312	DT	denotes	the
T19815	34306-34308	IN	denotes	in
T19814	34300-34305	VBN	denotes	found
T19813	34280-34288	VBN	denotes	observed
T19812	34289-34299	NNS	denotes	phenotypes
T19811	34276-34279	DT	denotes	the
T19810	34273-34275	IN	denotes	to
T19809	34260-34272	JJ	denotes	coincidental
T19808	34257-34259	VB	denotes	be
T19807	34253-34256	RB	denotes	not
T19806	34249-34252	MD	denotes	may
T19805	34246-34248	CC	denotes	or
T19804	34242-34245	MD	denotes	may
T19803	34238-34241	CC	denotes	and
T19802	34233-34237	NN	denotes	time
T19801	34222-34232	NN	denotes	rebleeding
T19800	34218-34221	IN	denotes	for
T19799	34214-34217	NN	denotes	QTL
T19798	34210-34213	IN	denotes	for
T19797	34199-34209	VBN	denotes	identified
T19796	34181-34186	CD	denotes	three
T19795	34187-34198	NNS	denotes	chromosomes
T19794	34177-34180	DT	denotes	the
T19793	34174-34176	IN	denotes	on
T19792	34154-34155	HYPH	denotes	-
T19791	34155-34166	NN	denotes	antiplasmin
T19790	34152-34154	NN	denotes	α2
T19789	34148-34151	CC	denotes	and
T19788	34146-34148	,	denotes	,
T19787	34145-34146	CD	denotes	1
T19786	34144-34145	HYPH	denotes	-
T19785	34141-34144	NN	denotes	PAI
T19784	34139-34141	,	denotes	,
T19783	34136-34139	NN	denotes	Plg
T19782	34132-34135	IN	denotes	for
T19781	34167-34173	VBP	denotes	reside
T19780	34126-34131	NNS	denotes	genes
T19779	34122-34125	DT	denotes	The
T19778	34121-34330	sentence	denotes	The genes for Plg, PAI-1, and α2-antiplasmin reside on the three chromosomes identified for QTL for rebleeding time and may or may not be coincidental to the observed phenotypes found in the A/J mice and CSS.
T19777	34120-34121	.	denotes	.
T19776	34107-34120	NN	denotes	investigation
T19775	34099-34106	JJ	denotes	further
T19774	34091-34098	VB	denotes	warrant
T19773	34087-34090	CC	denotes	and
T19772	34079-34080	HYPH	denotes	/
T19771	34080-34081	NN	denotes	J
T19770	34078-34079	NN	denotes	A
T19769	34082-34086	NNS	denotes	mice
T19768	34074-34077	DT	denotes	the
T19767	34071-34073	IN	denotes	in
T19766	34056-34065	NN	denotes	occlusion
T19765	34048-34055	VBD	denotes	reduced
T19764	34044-34047	CC	denotes	and
T19763	34033-34043	NN	denotes	rebleeding
T19762	34023-34032	VBN	denotes	increased
T19761	34066-34070	NN	denotes	time
T19760	34019-34022	DT	denotes	the
T19759	34016-34018	IN	denotes	to
T19758	34001-34004	MD	denotes	may
T19757	33985-33991	NN	denotes	matrix
T19756	33992-34000	NN	denotes	proteins
T19755	33971-33984	JJ	denotes	extracellular
T19754	33968-33970	CC	denotes	or
T19753	33959-33967	NN	denotes	collagen
T19752	33956-33958	IN	denotes	of
T19751	33945-33955	NN	denotes	metabolism
T19750	33942-33944	CC	denotes	or
T19749	33941-33942	HYPH	denotes	/
T19748	33938-33941	CC	denotes	and
T19747	33928-33937	NN	denotes	structure
T19746	33924-33927	DT	denotes	the
T19745	33921-33923	IN	denotes	in
T19744	34005-34015	VB	denotes	contribute
T19743	33909-33920	NNS	denotes	Differences
T19742	33908-34121	sentence	denotes	Differences in the structure and/or metabolism of collagen or extracellular matrix proteins may contribute to the increased rebleeding and reduced occlusion time in the A/J mice and warrant further investigation.
T19227	31533-31535	,	denotes	,
T19226	31516-31524	NN	denotes	platelet
T19225	31525-31533	NN	denotes	function
T19224	31509-31515	JJ	denotes	normal
T19223	31505-31508	IN	denotes	for
T19222	31496-31504	VBN	denotes	required
T19221	31488-31495	NNS	denotes	factors
T19220	31485-31487	IN	denotes	in
T19219	31475-31484	JJ	denotes	deficient
T19218	31471-31474	VBP	denotes	are
T19217	31466-31470	WDT	denotes	that
T19216	31611-31620	VBN	denotes	increased
T19215	31461-31465	NNS	denotes	Mice
T19214	31460-31640	sentence	denotes	Mice that are deficient in factors required for normal platelet function, platelet glycoprotein Ib [30], and protease-activated receptor-4, [31] have increased tail bleeding time.
T19213	31459-31460	.	denotes	.
T19212	31450-31459	NN	denotes	stability
T19211	31446-31449	CC	denotes	and
T19210	31436-31445	NN	denotes	formation
T19209	31427-31435	NN	denotes	thrombus
T19208	31424-31426	IN	denotes	on
T19207	31413-31423	NNS	denotes	influences
T19206	31405-31412	JJ	denotes	genetic
T19205	31402-31404	IN	denotes	of
T19204	31383-31392	JJ	denotes	sensitive
T19203	31393-31401	NN	denotes	reporter
T19202	31381-31382	DT	denotes	a
T19201	31374-31377	MD	denotes	may
T19200	31369-31373	NN	denotes	time
T19199	31358-31368	NN	denotes	rebleeding
T19198	31378-31380	VB	denotes	be
T19149	31071-31081	NNP	denotes	Willebrand
T19148	31067-31070	NNP	denotes	von
T19147	31082-31089	NN	denotes	antigen
T19146	31059-31066	VBN	denotes	reduced
T19145	31056-31058	IN	denotes	to
T19144	31052-31055	IN	denotes	due
T19143	31038-31046	NN	denotes	bleeding
T19142	31047-31051	NN	denotes	time
T19141	31028-31037	VBN	denotes	increased
T19140	31020-31022	TO	denotes	to
T19139	31023-31027	VB	denotes	have
T19138	31012-31013	HYPH	denotes	/
T19137	31013-31014	NN	denotes	J
T19136	31008-31012	NN	denotes	RIIS
T19135	31004-31007	DT	denotes	the
T19134	31015-31019	NNS	denotes	mice
T19133	30999-31003	RB	denotes	only
T19132	30993-30998	VBN	denotes	found
T19131	30989-30992	CC	denotes	and
T19130	30984-30988	NNS	denotes	mice
T19129	30981-30983	IN	denotes	of
T19128	30973-30980	NNS	denotes	strains
T19127	30970-30972	CD	denotes	25
T19126	30959-30960	-RRB-	denotes	]
T19125	30957-30959	CD	denotes	28
T19124	30956-30957	-LRB-	denotes	[
T19123	30953-30955	FW	denotes	al
T19122	30950-30952	FW	denotes	et
T19121	30961-30969	VBD	denotes	screened
T19120	30943-30949	NNP	denotes	Sweeny
T19119	30942-31090	sentence	denotes	Sweeny et al [28] screened 25 strains of mice and found only the RIIS/J mice to have increased bleeding time due to reduced von Willebrand antigen.
T19118	30941-30942	.	denotes	.
T19117	30937-30941	NNS	denotes	mice
T19116	30934-30936	IN	denotes	in
T19115	30913-30924	NN	denotes	coagulation
T19114	30909-30912	CC	denotes	and
T19113	30925-30933	NN	denotes	proteins
T19112	30900-30908	NN	denotes	platelet
T19111	30897-30899	IN	denotes	of
T19110	30886-30896	NN	denotes	expression
T19109	30881-30885	RB	denotes	over
T19108	30877-30880	CC	denotes	and
T19107	30864-30876	NNS	denotes	deficiencies
T19106	30861-30863	IN	denotes	of
T19105	30854-30860	NN	denotes	impact
T19104	30850-30853	DT	denotes	the
T19103	30843-30849	VB	denotes	assess
T19102	30840-30842	TO	denotes	to
T19101	30835-30839	NNS	denotes	mice
T19100	30832-30834	IN	denotes	in
T19099	30820-30831	RB	denotes	extensively
T19098	30810-30814	VBN	denotes	been
T19097	30806-30809	VBZ	denotes	has
T19096	30815-30819	VBN	denotes	used
T19095	30790-30791	HYPH	denotes	-
T19094	30791-30799	NN	denotes	bleeding
T19093	30786-30790	NN	denotes	tail
T19092	30800-30805	NN	denotes	assay
T19091	30782-30785	DT	denotes	The
T19090	30781-30942	sentence	denotes	The tail-bleeding assay has been used extensively in mice to assess the impact of deficiencies and over expression of platelet and coagulation proteins in mice.
T19089	30780-30781	.	denotes	.
T19088	30771-30780	NN	denotes	formation
T19087	30762-30770	NN	denotes	thrombus
T19086	30752-30761	JJ	denotes	occlusive
T19085	30749-30751	IN	denotes	to
T19084	30741-30748	VBG	denotes	leading
T19083	30734-30740	NNS	denotes	events
T19082	30730-30733	DT	denotes	the
T19081	30717-30720	MD	denotes	can
T19080	30715-30717	,	denotes	,
T19079	30710-30715	NN	denotes	lysis
T19078	30705-30709	NN	denotes	clot
T19077	30702-30704	IN	denotes	of
T19076	30697-30701	NN	denotes	rate
T19075	30693-30696	DT	denotes	the
T19074	30686-30692	VBP	denotes	affect
T19073	30681-30685	WDT	denotes	that
T19072	30672-30680	NN	denotes	activity
T19071	30664-30671	NN	denotes	plasmin
T19070	30661-30663	IN	denotes	in
T19069	30649-30660	NNS	denotes	alterations
T19068	30721-30729	VB	denotes	modulate
T19067	30644-30648	IN	denotes	that
T19066	30633-30643	VBG	denotes	suggesting
T19065	30631-30633	,	denotes	,
T19064	30625-30626	SYM	denotes	-
T19063	30624-30625	HYPH	denotes	/
T19062	30623-30624	SYM	denotes	-
T19061	30620-30623	NN	denotes	PAI
T19060	30627-30631	NNS	denotes	mice
T19059	30616-30619	DT	denotes	the
T19058	30613-30615	IN	denotes	in
T19057	30603-30612	VBD	denotes	increased
T19056	30599-30602	CC	denotes	but
T19055	30597-30599	,	denotes	,
T19054	30591-30592	SYM	denotes	-
T19053	30590-30591	HYPH	denotes	/
T19052	30589-30590	SYM	denotes	-
T19051	30586-30589	NN	denotes	Plg
T19050	30593-30597	NNS	denotes	mice
T19049	30582-30585	DT	denotes	the
T19048	30579-30581	IN	denotes	in
T19047	30567-30570	VBD	denotes	was
T19046	30562-30566	NN	denotes	time
T19045	30552-30561	NN	denotes	formation
T19044	30543-30551	NN	denotes	thrombus
T19043	30541-30543	,	denotes	,
T19042	30540-30541	-RRB-	denotes	]
T19041	30538-30540	CD	denotes	27
T19040	30537-30538	-LRB-	denotes	[
T19039	30525-30528	NN	denotes	Plg
T19038	30529-30536	NN	denotes	network
T19037	30521-30524	DT	denotes	the
T19036	30518-30520	IN	denotes	of
T19035	30505-30517	NNS	denotes	deficiencies
T19034	30500-30504	IN	denotes	with
T19033	30495-30499	NNS	denotes	mice
T19032	30491-30494	DT	denotes	the
T19031	30571-30578	VBN	denotes	reduced
T19030	30488-30490	IN	denotes	In
T19029	30487-30781	sentence	denotes	In the mice with deficiencies of the Plg network [27], thrombus formation time was reduced in the Plg-/- mice, but increased in the PAI-/- mice, suggesting that alterations in plasmin activity that affect the rate of clot lysis, can modulate the events leading to occlusive thrombus formation.
T19028	30486-30487	.	denotes	.
T19027	30475-30478	CD	denotes	two
T19026	30479-30486	NNS	denotes	strains
T19025	30471-30474	DT	denotes	the
T19024	30468-30470	IN	denotes	in
T19023	30460-30467	JJ	denotes	similar
T19022	30456-30459	VBD	denotes	was
T19021	30451-30455	NN	denotes	time
T19020	30439-30450	NN	denotes	coagulation
T19019	30435-30438	CC	denotes	and
T19018	30433-30435	,	denotes	,
T19017	30416-30424	NN	denotes	platelet
T19016	30425-30433	NN	denotes	function
T19015	30407-30415	JJ	denotes	impaired
T19014	30402-30406	IN	denotes	with
T19013	30400-30401	-RRB-	denotes	]
T19012	30398-30400	CD	denotes	26
T19011	30397-30398	-LRB-	denotes	[
T19010	30386-30391	NN	denotes	Lepob
T19009	30392-30396	NNS	denotes	mice
T19008	30382-30385	DT	denotes	the
T19007	30378-30381	IN	denotes	for
T19006	30373-30377	IN	denotes	than
T19005	30363-30372	JJ	denotes	different
T19004	30344-30350	JJ	denotes	inbred
T19003	30340-30343	CD	denotes	two
T19002	30351-30358	NNS	denotes	strains
T19001	30336-30339	DT	denotes	the
T19000	30332-30335	IN	denotes	for
T18999	30322-30331	NN	denotes	cessation
T18998	30317-30321	NN	denotes	flow
T18997	30311-30316	NN	denotes	blood
T18996	30308-30310	IN	denotes	of
T18995	30359-30362	VBD	denotes	was
T18994	30300-30307	NN	denotes	pattern
T18993	30296-30299	DT	denotes	The
T18992	30295-30487	sentence	denotes	The pattern of blood flow cessation for the two inbred strains was different than for the Lepob mice [26] with impaired platelet function, and coagulation time was similar in the two strains.
T18991	30294-30295	.	denotes	.
T18990	30287-30288	HYPH	denotes	/
T18989	30288-30289	NN	denotes	J
T18988	30286-30287	NN	denotes	A
T18987	30282-30285	CC	denotes	and
T18986	30290-30294	NNS	denotes	mice
T18985	30279-30281	NN	denotes	B6
T18984	30276-30278	IN	denotes	in
T18983	30267-30275	NN	denotes	thrombus
T18982	30263-30266	DT	denotes	the
T18981	30260-30262	IN	denotes	of
T18980	30248-30259	NN	denotes	composition
T18979	30244-30247	DT	denotes	the
T18978	30241-30243	IN	denotes	in
T18977	30229-30240	NNS	denotes	differences
T18976	30218-30222	VBP	denotes	have
T18975	30215-30217	PRP	denotes	we
T18974	30213-30215	,	denotes	,
T18973	30206-30213	NNS	denotes	studies
T18972	30194-30205	JJ	denotes	preliminary
T18971	30223-30228	VBN	denotes	noted
T18970	30191-30193	IN	denotes	In
T18969	30190-30295	sentence	denotes	In preliminary studies, we have noted differences in the composition of the thrombus in B6 and A/J mice.
T18968	30189-30190	.	denotes	.
T18967	30182-30183	HYPH	denotes	/
T18966	30183-30184	NN	denotes	J
T18965	30181-30182	NN	denotes	A
T18964	30177-30180	CC	denotes	and
T19525	32906-32912	NNS	denotes	values
T19524	32898-32905	JJ	denotes	similar
T19523	32887-32891	VBP	denotes	have
T19522	32892-32897	VBN	denotes	found
T19521	32884-32886	PRP	denotes	We
T19520	32883-33022	sentence	denotes	We have found similar values for Plg-/- mice in a 50%B6:50%129 background (J. Hoover-Plow, A. Shchurin, and E. Hart, unpublished results).
T19519	32882-32883	.	denotes	.
T19518	32876-32877	SYM	denotes	-
T19517	32875-32876	HYPH	denotes	/
T19516	32874-32875	SYM	denotes	-
T19515	32878-32882	NNS	denotes	mice
T19514	32871-32874	NN	denotes	Plg
T19513	32867-32870	IN	denotes	for
T19512	32847-32857	RB	denotes	previously
T19511	32842-32846	VBN	denotes	been
T19510	32838-32841	RB	denotes	not
T19509	32834-32837	VBZ	denotes	has
T19508	32858-32866	VBN	denotes	reported
T19507	32829-32833	NN	denotes	time
T19506	32820-32828	NN	denotes	Bleeding
T19505	32819-32883	sentence	denotes	Bleeding time has not been previously reported for Plg-/- mice.
T19504	32818-32819	.	denotes	.
T19503	32813-32818	NN	denotes	study
T19502	32809-32812	PRP$	denotes	our
T19501	32806-32808	IN	denotes	in
T19500	32797-32805	VBN	denotes	reported
T19499	32791-32796	NNS	denotes	times
T19498	32787-32790	DT	denotes	the
T19497	32784-32786	IN	denotes	to
T19496	32775-32783	VBN	denotes	compared
T19495	32767-32774	JJ	denotes	reduced
T19494	32761-32766	NNS	denotes	times
T19493	32752-32760	NN	denotes	bleeding
T19492	32748-32751	CC	denotes	and
T19491	32740-32747	JJR	denotes	shorter
T19490	32727-32739	RB	denotes	considerably
T19489	32723-32726	VBD	denotes	was
T19488	32710-32714	NN	denotes	clip
T19487	32705-32709	NN	denotes	tail
T19486	32715-32722	NN	denotes	segment
T19485	32701-32704	DT	denotes	the
T19484	32697-32700	CC	denotes	but
T19483	32695-32697	,	denotes	,
T19482	32688-32695	JJ	denotes	similar
T19481	32684-32687	VBD	denotes	was
T19480	32678-32683	NN	denotes	assay
T19479	32674-32677	DT	denotes	the
T19478	32670-32673	CC	denotes	and
T19477	32668-32670	,	denotes	,
T19476	32664-32668	NNS	denotes	mice
T19475	32661-32663	NN	denotes	WT
T19474	32658-32660	IN	denotes	to
T19473	32649-32657	VBN	denotes	compared
T19472	32642-32643	SYM	denotes	-
T19471	32641-32642	HYPH	denotes	/
T19470	32640-32641	SYM	denotes	-
T19469	32639-32640	CD	denotes	1
T19468	32638-32639	HYPH	denotes	-
T19467	32635-32638	NN	denotes	PAI
T19466	32633-32635	,	denotes	,
T19465	32632-32633	SYM	denotes	-
T19464	32631-32632	HYPH	denotes	/
T19463	32630-32631	SYM	denotes	-
T19462	32627-32630	NN	denotes	uPA
T19461	32625-32627	,	denotes	,
T19460	32624-32625	SYM	denotes	-
T19459	32623-32624	HYPH	denotes	/
T19458	32622-32623	SYM	denotes	-
T19457	32644-32648	NNS	denotes	mice
T19456	32619-32622	NN	denotes	tPA
T19455	32615-32618	IN	denotes	for
T19454	32610-32614	NN	denotes	time
T19453	32601-32609	NN	denotes	bleeding
T19452	32598-32600	IN	denotes	in
T19451	32587-32597	NN	denotes	difference
T19450	32584-32586	DT	denotes	no
T19449	32573-32574	-RRB-	denotes	]
T19448	32571-32573	CD	denotes	32
T19447	32570-32571	-LRB-	denotes	[
T19446	32567-32569	FW	denotes	al
T19445	32564-32566	FW	denotes	et
T19444	32575-32583	VBD	denotes	reported
T19443	32556-32563	NNP	denotes	Matsuno
T19442	32555-32819	sentence	denotes	Matsuno et al [32] reported no difference in bleeding time for tPA-/-, uPA-/-, PAI-1-/- mice compared to WT mice, and the assay was similar, but the tail clip segment was considerably shorter and bleeding times reduced compared to the times reported in our study.
T19441	32554-32555	.	denotes	.
T19440	32541-32549	VBN	denotes	targeted
T19439	32533-32540	NN	denotes	network
T19438	32529-32532	NN	denotes	Plg
T19437	32550-32554	NNS	denotes	mice
T19436	32525-32528	DT	denotes	the
T19435	32522-32524	IN	denotes	of
T19434	32518-32521	DT	denotes	any
T19433	32515-32517	IN	denotes	in
T19432	32501-32505	VBN	denotes	been
T19431	32497-32500	RB	denotes	not
T19430	32492-32496	VBP	denotes	have
T19429	32506-32514	VBN	denotes	reported
T19428	32475-32485	NN	denotes	rebleeding
T19427	32472-32474	CC	denotes	or
T19426	32463-32471	NN	denotes	bleeding
T19425	32486-32491	NNS	denotes	times
T19424	32453-32462	VBN	denotes	Increased
T19423	32452-32555	sentence	denotes	Increased bleeding or rebleeding times have not been reported in any of the Plg network targeted mice.
T19422	32451-32452	.	denotes	.
T19421	32450-32451	-RRB-	denotes	)
T19420	32443-32450	NNS	denotes	results
T19419	32431-32442	JJ	denotes	unpublished
T19418	32429-32431	,	denotes	,
T19417	32425-32429	NNP	denotes	Hart
T19416	32422-32424	NNP	denotes	E.
T19415	32418-32421	CC	denotes	and
T19414	32416-32418	,	denotes	,
T18963	30174-30176	NN	denotes	B6
T18962	30185-30189	NNS	denotes	mice
T18961	30170-30173	DT	denotes	the
T18960	30167-30169	IN	denotes	in
T18959	30151-30160	NN	denotes	occlusion
T18958	30161-30166	NNS	denotes	rates
T18957	30142-30150	JJ	denotes	arterial
T18956	30139-30141	IN	denotes	to
T18955	30130-30138	NNS	denotes	carotids
T18954	30126-30129	DT	denotes	the
T18953	30123-30125	IN	denotes	of
T18952	30116-30122	NN	denotes	stress
T18951	30110-30115	JJ	denotes	sheer
T18950	30106-30109	CC	denotes	and
T18949	30101-30105	NN	denotes	size
T18948	30098-30100	IN	denotes	in
T18947	30086-30097	NNS	denotes	differences
T18946	30082-30085	DT	denotes	the
T18945	30079-30081	IN	denotes	in
T18944	30066-30078	NN	denotes	contribution
T18943	30062-30065	DT	denotes	the
T18942	30052-30061	VB	denotes	determine
T18941	30049-30051	TO	denotes	to
T18940	30039-30048	JJ	denotes	necessary
T18939	30030-30035	MD	denotes	would
T18938	30024-30029	NN	denotes	study
T18937	30019-30023	DT	denotes	this
T18936	30016-30018	IN	denotes	of
T18935	30010-30015	NN	denotes	scope
T18934	30006-30009	DT	denotes	the
T18871	29689-29692	CC	denotes	and
T18870	29679-29688	NN	denotes	formation
T18869	29670-29678	NN	denotes	thrombus
T18868	29668-29670	,	denotes	,
T18867	29659-29668	NN	denotes	treatment
T18866	29653-29658	NN	denotes	FeCl3
T18865	29718-29727	VBN	denotes	shortened
T18864	29647-29652	IN	denotes	After
T18863	29646-29768	sentence	denotes	After FeCl3 treatment, thrombus formation and occlusion was remarkably shortened in the A/J mice compared to the B6 mice.
T18862	29645-29646	.	denotes	.
T18861	29639-29645	NN	denotes	injury
T18860	29633-29638	NN	denotes	FeCl3
T18859	29627-29632	IN	denotes	after
T18858	29612-29619	JJ	denotes	carotid
T18857	29620-29626	NN	denotes	artery
T18856	29608-29611	DT	denotes	the
T18855	29605-29607	IN	denotes	of
T18854	29595-29604	NN	denotes	occlusion
T18853	29591-29594	IN	denotes	for
T18852	29586-29590	NN	denotes	time
T18851	29582-29585	DT	denotes	the
T18850	29579-29581	IN	denotes	in
T18849	29567-29578	NNS	denotes	differences
T18848	29560-29566	JJ	denotes	marked
T18847	29556-29559	VBD	denotes	had
T18846	29541-29547	JJ	denotes	inbred
T18845	29537-29540	CD	denotes	two
T18844	29548-29555	NNS	denotes	strains
T18843	29533-29536	DT	denotes	The
T18842	29532-29646	sentence	denotes	The two inbred strains had marked differences in the time for occlusion of the carotid artery after FeCl3 injury.
T18841	29531-29532	.	denotes	.
T18840	29530-29531	-RRB-	denotes	]
T18839	29528-29530	CD	denotes	24
T18838	29527-29528	-LRB-	denotes	[
T18837	29497-29512	JJ	denotes	pharmacological
T18836	29493-29496	CC	denotes	and
T18835	29513-29526	NNS	denotes	interventions
T18834	29485-29492	JJ	denotes	genetic
T18833	29476-29484	VB	denotes	evaluate
T18832	29473-29475	TO	denotes	to
T18831	29461-29467	RB	denotes	widely
T18830	29457-29460	RB	denotes	now
T18829	29454-29456	VBZ	denotes	is
T18828	29449-29453	NNS	denotes	mice
T18827	29446-29448	IN	denotes	in
T18826	29435-29445	NN	denotes	thrombosis
T18825	29431-29434	CC	denotes	and
T18824	29424-29430	NN	denotes	injury
T18823	29415-29423	JJ	denotes	vascular
T18822	29412-29414	IN	denotes	of
T18821	29468-29472	VBN	denotes	used
T18820	29397-29398	HYPH	denotes	-
T18819	29398-29405	VBN	denotes	induced
T18818	29392-29397	NN	denotes	FeCl3
T18817	29406-29411	NN	denotes	model
T18816	29388-29391	DT	denotes	The
T18815	29387-29532	sentence	denotes	The FeCl3-induced model of vascular injury and thrombosis in mice is now widely used to evaluate genetic and pharmacological interventions [24].
T18814	29386-29387	.	denotes	.
T18813	29384-29386	CD	denotes	17
T18812	29380-29383	CC	denotes	and
T18811	29378-29379	CD	denotes	5
T18810	29376-29378	,	denotes	,
T18809	29365-29376	NNS	denotes	chromosomes
T18808	29362-29364	IN	denotes	of
T18807	29358-29361	CD	denotes	two
T18806	29354-29357	IN	denotes	for
T18805	29342-29353	JJ	denotes	heterosomic
T18804	29335-29341	RB	denotes	doubly
T18803	29332-29334	IN	denotes	in
T18802	29322-29331	VBD	denotes	increased
T18801	29318-29321	CC	denotes	but
T18800	29316-29318	,	denotes	,
T18799	29298-29308	JJ	denotes	homozygous
T18798	29295-29297	CD	denotes	17
T18797	29294-29295	HYPH	denotes	-
T18796	29291-29294	NN	denotes	CSS
T18795	29287-29290	CC	denotes	and
T18794	29285-29286	CD	denotes	5
T18793	29284-29285	HYPH	denotes	-
T18792	29281-29284	NN	denotes	CSS
T18791	29309-29316	NNS	denotes	strains
T18790	29277-29280	DT	denotes	the
T18789	29274-29276	IN	denotes	in
T18788	29271-29273	NN	denotes	B6
T18787	29268-29270	IN	denotes	to
T18786	29260-29267	JJ	denotes	similar
T18785	29256-29259	VBD	denotes	was
T18784	29251-29255	NN	denotes	time
T18783	29241-29250	NN	denotes	occlusion
T18782	29232-29240	JJ	denotes	Arterial
T18781	29231-29387	sentence	denotes	Arterial occlusion time was similar to B6 in the CSS-5 and CSS-17 homozygous strains, but increased in doubly heterosomic for two of chromosomes, 5 and 17.
T18780	29230-29231	.	denotes	.
T18779	29228-29230	CD	denotes	17
T18778	29224-29227	CC	denotes	and
T18777	29222-29223	CD	denotes	5
T18776	29220-29222	,	denotes	,
T18775	29209-29220	NNS	denotes	chromosomes
T18774	29206-29208	IN	denotes	of
T18773	29202-29205	CD	denotes	two
T18772	29198-29201	IN	denotes	for
T18771	29179-29185	RB	denotes	doubly
T18770	29186-29197	JJ	denotes	heterosomic
T18769	29175-29178	DT	denotes	the
T18768	29172-29174	IN	denotes	in
T18767	29158-29162	VBD	denotes	were
T18766	29163-29171	VBN	denotes	restored
T18765	29151-29157	NNS	denotes	Values
T18764	29150-29231	sentence	denotes	Values were restored in the doubly heterosomic for two of chromosomes, 5 and 17.
T18763	29149-29150	.	denotes	.
T18762	29140-29142	CD	denotes	11
T18761	29139-29140	HYPH	denotes	-
T18760	29136-29139	NN	denotes	CSS
T18759	29143-29149	NN	denotes	strain
T18758	29132-29135	DT	denotes	the
T18757	29129-29131	IN	denotes	in
T18756	29125-29128	RB	denotes	not
T18755	29121-29124	CC	denotes	but
T18754	29119-29121	,	denotes	,
T18753	29114-29115	HYPH	denotes	-
T18752	29115-29119	NN	denotes	17F1
T18751	29111-29114	NN	denotes	CSS
T18750	29107-29110	CC	denotes	and
T18749	29102-29103	HYPH	denotes	-
T18748	29103-29106	NN	denotes	5F1
T18747	29099-29102	NN	denotes	CSS
T18746	29097-29099	,	denotes	,
T18745	29081-29092	JJ	denotes	heterosomic
T18744	29093-29097	NNS	denotes	mice
T18743	29077-29080	DT	denotes	the
T18742	29073-29076	CC	denotes	and
T18741	29070-29072	CD	denotes	17
T18740	29069-29070	HYPH	denotes	-
T18739	29066-29069	NN	denotes	CSS
T18738	29062-29065	CC	denotes	and
T18737	29060-29061	CD	denotes	5
T18736	29059-29060	HYPH	denotes	-
T18735	29056-29059	NN	denotes	CSS
T18734	29051-29055	CC	denotes	both
T18733	29048-29050	IN	denotes	in
T18732	29033-29037	VBD	denotes	were
T18731	29024-29032	NN	denotes	activity
T18730	29020-29023	CC	denotes	and
T18729	29012-29019	NN	denotes	antigen
T18728	29010-29011	CD	denotes	1
T18727	29009-29010	HYPH	denotes	-
T18726	29038-29047	VBN	denotes	decreased
T18725	29006-29009	NN	denotes	PAI
T18724	29005-29150	sentence	denotes	PAI-1 antigen and activity were decreased in both CSS-5 and CSS-17 and the heterosomic mice, CSS-5F1 and CSS-17F1, but not in the CSS-11 strain.
T18723	29004-29005	.	denotes	.
T18722	28989-28999	NN	denotes	rebleeding
T18721	29000-29004	NN	denotes	time
T18720	28980-28988	VBN	denotes	elevated
T18719	28978-28980	,	denotes	,
T18718	28966-28967	HYPH	denotes	/
T18717	28967-28968	NN	denotes	J
T18716	28965-28966	NN	denotes	A
T18715	28969-28978	NN	denotes	phenotype
T18714	28961-28964	DT	denotes	the
T18713	28953-28960	VB	denotes	express
T18712	28950-28952	TO	denotes	to
T18711	28936-28940	VBD	denotes	were
T18710	28934-28936	,	denotes	,
T18709	28932-28934	CD	denotes	17
T18708	28928-28931	CC	denotes	and
T18707	28926-28927	CD	denotes	5
T18706	28924-28926	,	denotes	,
T18705	28913-28924	NNS	denotes	chromosomes
T18704	28909-28912	DT	denotes	the
T18703	28906-28908	IN	denotes	of
T18702	28902-28905	CD	denotes	two
T18701	28898-28901	IN	denotes	for
T18700	28886-28897	JJ	denotes	heterosomic
T18699	28879-28885	RB	denotes	doubly
T18698	28876-28878	CC	denotes	or
T18697	28864-28875	NNS	denotes	chromosomes
T18696	28858-28863	DT	denotes	these
T18695	28854-28857	IN	denotes	for
T18694	28844-28853	JJ	denotes	homosomic
T18693	28941-28949	VBN	denotes	required
T18692	28839-28843	NNS	denotes	Mice
T18691	28838-29005	sentence	denotes	Mice homosomic for these chromosomes or doubly heterosomic for two of the chromosomes, 5 and 17, were required to express the A/J phenotype, elevated rebleeding time.
T18690	28837-28838	.	denotes	.
T18689	28822-28832	NN	denotes	rebleeding
T18688	28833-28837	NN	denotes	time
T18687	28812-28821	VBN	denotes	increased
T18686	28809-28811	IN	denotes	of
T19197	31353-31357	IN	denotes	that
T19196	31341-31352	NN	denotes	possibility
T19195	31337-31340	DT	denotes	the
T19194	31330-31336	VBD	denotes	raised
T19193	31318-31329	NN	denotes	observation
T19192	31313-31317	DT	denotes	This
T19191	31312-31460	sentence	denotes	This observation raised the possibility that rebleeding time may be a sensitive reporter of genetic influences on thrombus formation and stability.
T19190	31311-31312	.	denotes	.
T19189	31307-31311	NNS	denotes	mice
T19188	31293-31296	NN	denotes	FIX
T19187	31289-31292	CC	denotes	and
T19186	31297-31306	JJ	denotes	deficient
T19185	31283-31288	NN	denotes	FVIII
T19184	31280-31282	IN	denotes	in
T19183	31275-31279	NN	denotes	tail
T19182	31271-31274	DT	denotes	the
T19181	31268-31270	IN	denotes	of
T19180	31253-31267	NN	denotes	electrocautery
T19179	31245-31252	IN	denotes	despite
T19178	31224-31234	NN	denotes	rebleeding
T19177	31222-31224	,	denotes	,
T19176	31209-31212	RB	denotes	not
T19175	31205-31208	VBD	denotes	was
T19174	31200-31204	NN	denotes	time
T19173	31191-31199	NN	denotes	bleeding
T19172	31213-31222	VBN	denotes	increased
T19171	31185-31190	IN	denotes	while
T19170	31235-31244	VBD	denotes	persisted
T19169	31180-31184	IN	denotes	that
T19168	31174-31179	VBD	denotes	found
T19167	31170-31173	CC	denotes	and
T19166	31150-31161	NN	denotes	coagulation
T19165	31162-31169	NN	denotes	pathway
T19164	31146-31149	DT	denotes	the
T19163	31143-31145	IN	denotes	of
T19162	31133-31142	NNS	denotes	deletions
T19161	31128-31132	NN	denotes	gene
T19160	31123-31127	IN	denotes	with
T19159	31118-31122	NNS	denotes	mice
T19158	31106-31107	-RRB-	denotes	]
T19157	31104-31106	CD	denotes	29
T19156	31103-31104	-LRB-	denotes	[
T19155	31100-31102	FW	denotes	al
T19154	31097-31099	FW	denotes	et
T19153	31108-31117	VBN	denotes	evaluated
T19152	31091-31096	NNP	denotes	Broze
T19151	31090-31312	sentence	denotes	Broze et al [29] evaluated mice with gene deletions of the coagulation pathway and found that while bleeding time was not increased, rebleeding persisted despite electrocautery of the tail in FVIII and FIX deficient mice.
T19150	31089-31090	.	denotes	.
T18685	28796-28797	HYPH	denotes	/
T18684	28797-28798	NN	denotes	J
T18683	28795-28796	NN	denotes	A
T18682	28799-28808	NN	denotes	phenotype
T18681	28791-28794	DT	denotes	the
T18680	28788-28790	IN	denotes	to
T18679	28776-28787	VBD	denotes	contributed
T18678	28770-28775	WDT	denotes	which
T18677	28764-28769	NNS	denotes	genes
T18676	28755-28763	VBD	denotes	harbored
T18675	28750-28754	WDT	denotes	that
T18674	28738-28749	NNS	denotes	chromosomes
T18673	28732-28737	CD	denotes	three
T18672	28717-28720	NN	denotes	CSS
T18671	28713-28716	DT	denotes	the
T18670	28721-28731	VBD	denotes	identified
T18669	28703-28712	VBG	denotes	Screening
T18668	28702-28838	sentence	denotes	Screening the CSS identified three chromosomes that harbored genes which contributed to the A/J phenotype of increased rebleeding time.
T18667	28701-28702	.	denotes	.
T18666	28693-28701	NN	denotes	function
T18665	28684-28692	NN	denotes	platelet
T18664	28681-28683	CC	denotes	or
T18663	28669-28680	NN	denotes	coagulation
T18662	28666-28668	IN	denotes	in
T18661	28659-28665	NN	denotes	change
T18660	28654-28658	IN	denotes	with
T18659	28639-28642	RB	denotes	not
T18658	28634-28638	VBD	denotes	were
T18657	28643-28653	VBN	denotes	correlated
T18656	28613-28621	VBN	denotes	observed
T18933	29999-30005	IN	denotes	beyond
T18932	29997-29999	,	denotes	,
T18931	30036-30038	VB	denotes	be
T18930	29984-29997	NN	denotes	investigation
T18929	29976-29983	JJ	denotes	Further
T18928	29975-30190	sentence	denotes	Further investigation, beyond the scope of this study would be necessary to determine the contribution in the differences in size and sheer stress of the carotids to arterial occlusion rates in the B6 and A/J mice.
T18927	29974-29975	.	denotes	.
T18926	29957-29966	JJ	denotes	different
T18925	29967-29974	NNS	denotes	strains
T18924	29953-29956	DT	denotes	the
T18923	29948-29952	IN	denotes	with
T18922	29930-29935	NN	denotes	blood
T18921	29936-29940	NN	denotes	flow
T18920	29920-29929	VBN	denotes	increased
T18919	29915-29919	IN	denotes	with
T18918	29908-29914	NN	denotes	stress
T18917	29902-29907	JJ	denotes	sheer
T18916	29899-29901	IN	denotes	in
T18915	29891-29898	NNS	denotes	changes
T18914	29888-29890	IN	denotes	of
T18913	29878-29887	NN	denotes	magnitude
T18912	29874-29877	DT	denotes	the
T18911	29941-29947	VBD	denotes	varied
T18910	29869-29873	IN	denotes	that
T18909	29861-29863	,	denotes	,
T18908	29857-29861	NNS	denotes	rats
T18907	29854-29856	IN	denotes	in
T18906	29847-29853	NN	denotes	stress
T18905	29841-29846	JJ	denotes	sheer
T18904	29838-29840	IN	denotes	of
T18903	29836-29837	-RRB-	denotes	]
T18902	29834-29836	CD	denotes	25
T18901	29833-29834	-LRB-	denotes	[
T18900	29863-29868	VBD	denotes	found
T18899	29820-29826	JJ	denotes	recent
T18898	29827-29832	NN	denotes	study
T18897	29818-29819	DT	denotes	A
T18896	29817-29975	sentence	denotes	A recent study [25] of sheer stress in rats, found that the magnitude of changes in sheer stress with increased blood flow varied with the different strains.
T18895	29816-29817	.	denotes	.
T18894	29803-29807	VBN	denotes	been
T18893	29792-29802	RB	denotes	previously
T18892	29788-29791	RB	denotes	not
T18891	29783-29787	VBP	denotes	have
T18890	29808-29816	VBN	denotes	reported
T18889	29775-29782	NNS	denotes	results
T18888	29769-29774	DT	denotes	These
T18887	29768-29817	sentence	denotes	These results have not previously been reported.
T18886	29767-29768	.	denotes	.
T18885	29760-29762	NN	denotes	B6
T18884	29763-29767	NNS	denotes	mice
T18883	29756-29759	DT	denotes	the
T18882	29753-29755	IN	denotes	to
T18881	29744-29752	VBN	denotes	compared
T18880	29736-29737	HYPH	denotes	/
T18879	29737-29738	NN	denotes	J
T18878	29735-29736	NN	denotes	A
T18877	29739-29743	NNS	denotes	mice
T18876	29731-29734	DT	denotes	the
T18875	29728-29730	IN	denotes	in
T18874	29707-29717	RB	denotes	remarkably
T18873	29703-29706	VBD	denotes	was
T18872	29693-29702	NN	denotes	occlusion
T18655	28622-28633	NNS	denotes	differences
T18654	28609-28612	DT	denotes	the
T18653	28605-28608	CC	denotes	and
T18652	28603-28605	,	denotes	,
T18651	28601-28602	HYPH	denotes	/
T18650	28602-28603	NN	denotes	J
T18649	28600-28601	NN	denotes	A
T18648	28596-28599	CC	denotes	and
T18647	28593-28595	NN	denotes	B6
T18646	28591-28593	,	denotes	,
T18645	28577-28583	JJ	denotes	inbred
T18644	28573-28576	CD	denotes	two
T18643	28584-28591	NNS	denotes	strains
T18642	28569-28572	DT	denotes	the
T18641	28563-28568	IN	denotes	among
T18640	28543-28553	JJ	denotes	thrombotic
T18639	28554-28562	NN	denotes	response
T18638	28539-28542	DT	denotes	the
T18637	28536-28538	IN	denotes	in
T18636	28525-28529	VBD	denotes	were
T18635	28530-28535	VBN	denotes	found
T18634	28513-28524	NNS	denotes	differences
T18633	28506-28512	JJ	denotes	Marked
T18632	28505-28702	sentence	denotes	Marked differences were found in the thrombotic response among the two inbred strains, B6 and A/J, and the observed differences were not correlated with change in coagulation or platelet function.
T18631	28504-28505	.	denotes	.
T18630	28487-28495	NN	denotes	platelet
T18629	28479-28486	VBN	denotes	reduced
T18628	28496-28504	NN	denotes	function
T18627	28477-28478	DT	denotes	a
T18626	28472-28476	IN	denotes	with
T18625	28467-28471	NNS	denotes	mice
T18624	28457-28466	JJ	denotes	deficient
T18623	28450-28456	NN	denotes	leptin
T18622	28447-28449	IN	denotes	in
T18621	28439-28443	RB	denotes	well
T18620	28444-28446	IN	denotes	as
T18619	28436-28438	RB	denotes	as
T18618	28434-28436	,	denotes	,
T18617	28412-28424	JJ	denotes	fibrinolytic
T18616	28425-28434	NNS	denotes	responses
T18615	28404-28411	VBN	denotes	altered
T18614	28399-28403	IN	denotes	with
T18613	28387-28390	NN	denotes	Plg
T18612	28391-28398	NN	denotes	network
T18611	28383-28386	DT	denotes	the
T18610	28380-28382	IN	denotes	of
T18609	28375-28379	NNS	denotes	mice
T18608	28366-28374	VBN	denotes	targeted
T18607	28361-28365	NN	denotes	gene
T18606	28356-28360	IN	denotes	from
T18605	28349-28355	NNS	denotes	values
T18604	28346-28348	IN	denotes	to
T18603	28332-28336	VBD	denotes	were
T18602	28317-28323	JJ	denotes	inbred
T18601	28313-28316	CD	denotes	two
T18600	28324-28331	NNS	denotes	strains
T18599	28309-28312	DT	denotes	the
T18598	28306-28308	IN	denotes	of
T18597	28337-28345	VBN	denotes	compared
T18596	28294-28305	NNS	denotes	Assessments
T18595	28293-28505	sentence	denotes	Assessments of the two inbred strains were compared to values from gene targeted mice of the Plg network with altered fibrinolytic responses, as well as in leptin deficient mice with a reduced platelet function.
T18594	28292-28293	.	denotes	.
T18593	28284-28292	NN	denotes	response
T18592	28273-28283	JJ	denotes	thrombotic
T18591	28270-28272	IN	denotes	of
T18590	28259-28269	NNS	denotes	predictors
T18589	28249-28258	JJ	denotes	potential
T18588	28246-28248	IN	denotes	as
T18587	28231-28235	VBD	denotes	were
T18586	28215-28225	NN	denotes	rebleeding
T18585	28211-28214	CC	denotes	and
T18584	28226-28230	NN	denotes	time
T18583	28202-28210	NN	denotes	bleeding
T18582	28197-28201	NN	denotes	tail
T18581	28195-28197	,	denotes	,
T18580	28236-28245	VBN	denotes	evaluated
T18579	28191-28195	NN	denotes	time
T18578	28181-28190	NN	denotes	occlusion
T18577	28172-28180	JJ	denotes	Arterial
T18576	28171-28293	sentence	denotes	Arterial occlusion time, tail bleeding and rebleeding time were evaluated as potential predictors of thrombotic response.
T18575	28170-28171	.	denotes	.
T18574	28160-28170	NN	denotes	remodeling
T18573	28153-28159	NN	denotes	vessel
T18572	28149-28152	CC	denotes	and
T18571	28126-28136	JJ	denotes	neointimal
T18570	28137-28148	NN	denotes	hyperplasia
T18569	28117-28118	HYPH	denotes	-
T18568	28118-28125	VBN	denotes	induced
T18567	28109-28117	NN	denotes	ligation
T18566	28105-28108	CC	denotes	and
T18565	28103-28105	,	denotes	,
T18564	28088-28103	NN	denotes	atherosclerosis
T18563	28079-28080	HYPH	denotes	-
T18562	28080-28087	VBN	denotes	induced
T18561	28075-28079	NN	denotes	diet
T18560	28073-28075	,	denotes	,
T18559	28066-28073	NN	denotes	obesity
T18558	28057-28058	HYPH	denotes	-
T18557	28058-28065	VBN	denotes	induced
T18556	28053-28057	NN	denotes	diet
T18555	28050-28052	IN	denotes	to
T18554	28035-28049	NN	denotes	susceptibility
T18553	28032-28034	IN	denotes	in
T18552	28020-28031	NNS	denotes	differences
T18551	28013-28019	VBN	denotes	marked
T18550	28008-28012	VBP	denotes	have
T18549	28003-28007	WDT	denotes	that
T18548	27998-28002	NNS	denotes	mice
T18547	27995-27997	IN	denotes	of
T18546	27980-27986	JJ	denotes	inbred
T18545	27987-27994	NNS	denotes	strains
T18544	27976-27979	CD	denotes	two
T18543	27973-27975	IN	denotes	in
T18542	27949-27963	RB	denotes	systematically
T18541	27945-27948	VBD	denotes	was
T18540	27940-27944	NN	denotes	risk
T18539	27929-27939	JJ	denotes	thrombotic
T18538	27927-27929	,	denotes	,
T18537	27922-27927	NN	denotes	study
T18536	27917-27921	DT	denotes	this
T18535	27964-27972	VBN	denotes	assessed
T18534	27914-27916	IN	denotes	In
T14527	25914-25915	HYPH	denotes	/
T15073	27411-27412	.	denotes	.
T15072	27407-27411	NN	denotes	time
T15071	27397-27406	NN	denotes	occlusion
T15070	27388-27396	JJ	denotes	arterial
T15069	27372-27376	RB	denotes	also
T15068	27369-27371	CD	denotes	17
T15067	27365-27368	CC	denotes	and
T15066	27363-27364	CD	denotes	5
T15065	27352-27362	NN	denotes	chromosome
T15064	27349-27351	IN	denotes	on
T15063	27343-27348	NNS	denotes	genes
T15062	27339-27342	DT	denotes	the
T15061	27336-27338	IN	denotes	of
T15060	27324-27335	NN	denotes	interaction
T14555	25996-25998	NN	denotes	mL
T14554	25995-25996	SYM	denotes	/
T14553	25990-25993	CD	denotes	170
T14552	25994-25995	NNS	denotes	U
T14551	25989-25990	-LRB-	denotes	(
T14550	25980-25988	NN	denotes	activity
T14549	25976-25979	CC	denotes	and
T14548	25974-25975	-RRB-	denotes	)
T14547	25971-25972	SYM	denotes	=
T14546	25973-25974	CD	denotes	7
T14545	25969-25970	NN	denotes	n
T14544	25967-25969	,	denotes	,
T14543	25964-25967	CD	denotes	0.5
T14542	25962-25963	SYM	denotes	±
T14541	25959-25961	NN	denotes	mL
T14540	25958-25959	SYM	denotes	/
T14539	25952-25955	CD	denotes	5.4
T14538	25956-25958	NNS	denotes	ng
T14537	25951-25952	-LRB-	denotes	(
T14536	26031-26034	VBD	denotes	was
T14535	25941-25942	CD	denotes	1
T14534	25940-25941	HYPH	denotes	-
T14533	25937-25940	NN	denotes	PAI
T14532	25943-25950	NN	denotes	antigen
T14531	25933-25936	DT	denotes	The
T14530	25932-26066	sentence	denotes	The PAI-1 antigen (5.4 ng/mL ± 0.5, n = 7) and activity (170 U/mL ± 20, n = 6) in the CSS-11 mice was not different than for B6 mice.
T14529	25931-25932	.	denotes	.
T14528	25917-25923	NN	denotes	parent
T14526	25915-25916	NN	denotes	J
T14525	25913-25914	NN	denotes	A
T14524	25909-25912	CC	denotes	and
T14523	25906-25908	NN	denotes	B6
T14522	25924-25931	NNS	denotes	strains
T14521	25902-25905	DT	denotes	the
T14520	25899-25901	IN	denotes	of
T14519	25893-25898	NN	denotes	value
T14518	25889-25892	DT	denotes	the
T14517	25886-25888	IN	denotes	to
T14516	25873-25876	VBD	denotes	was
T14515	25862-25863	CD	denotes	1
T14514	25861-25862	HYPH	denotes	-
T14513	25864-25872	NN	denotes	activity
T14512	25858-25861	NN	denotes	PAI
T14511	25854-25857	IN	denotes	for
T14510	25848-25853	NN	denotes	value
T14509	25844-25847	DT	denotes	the
T14508	25834-25836	CD	denotes	17
T14507	25833-25834	HYPH	denotes	-
T14506	25830-25833	NN	denotes	CSS
T14505	25828-25829	SYM	denotes	×
T14504	25826-25827	CD	denotes	5
T14503	25825-25826	HYPH	denotes	-
T14502	25822-25825	NN	denotes	CSS
T14501	25837-25843	NN	denotes	strain
T14500	25818-25821	DT	denotes	the
T14499	25815-25817	IN	denotes	in
T14498	25877-25885	VBN	denotes	restored
T14497	25809-25814	RB	denotes	again
T14496	25805-25808	CC	denotes	but
T14495	25803-25805	,	denotes	,
T14494	25793-25794	HYPH	denotes	-
T14493	25794-25798	NN	denotes	17F1
T14492	25790-25793	NN	denotes	CSS
T14491	25786-25789	CC	denotes	and
T14490	25784-25785	CD	denotes	5
T14489	25783-25784	HYPH	denotes	-
T14488	25780-25783	NN	denotes	CSS
T14487	25799-25803	NNS	denotes	mice
T14486	25776-25779	DT	denotes	the
T14485	25773-25775	IN	denotes	in
T14484	25751-25764	RB	denotes	significantly
T14483	25747-25750	VBD	denotes	was
T14482	25765-25772	VBN	denotes	reduced
T14481	25736-25737	CD	denotes	1
T14480	25735-25736	HYPH	denotes	-
T14479	25738-25746	NN	denotes	activity
T14478	25732-25735	NN	denotes	PAI
T14477	25731-25932	sentence	denotes	PAI-1 activity was significantly reduced in the CSS-5 and CSS-17F1 mice, but again in the CSS-5 × CSS-17 strain the value for PAI-1 activity was restored to the value of the B6 and A/J parent strains.
T14476	25730-25731	.	denotes	.
T14475	25716-25722	NN	denotes	parent
T14474	25713-25714	HYPH	denotes	/
T14473	25714-25715	NN	denotes	J
T14472	25712-25713	NN	denotes	A
T14471	25708-25711	CC	denotes	and
T14470	25705-25707	NN	denotes	B6
T14469	25723-25730	NNS	denotes	strains
T14468	25701-25704	DT	denotes	the
T14467	25698-25700	IN	denotes	to
T14466	25690-25697	JJ	denotes	similar
T14465	25683-25689	NNS	denotes	values
T14464	25679-25682	VBD	denotes	had
T14463	25659-25670	JJ	denotes	heterosomic
T14462	25652-25658	JJ	denotes	double
T14461	25649-25651	CD	denotes	17
T15059	27377-27387	VBZ	denotes	determines
T15058	27319-27323	IN	denotes	that
T15057	27303-27310	NNS	denotes	results
T15056	27299-27302	DT	denotes	the
T15055	27297-27299	,	denotes	,
T15054	27279-27287	JJ	denotes	arterial
T15053	27288-27297	NN	denotes	occlusion
T15052	27275-27278	DT	denotes	the
T15051	27271-27274	IN	denotes	for
T15050	27311-27318	VBP	denotes	suggest
T15049	27259-27263	VBN	denotes	been
T15048	27254-27258	VBP	denotes	have
T15047	27249-27253	NNS	denotes	mice
T15046	27245-27248	NN	denotes	CSS
T15045	27242-27244	IN	denotes	of
T15044	27229-27234	JJ	denotes	small
T15043	27227-27228	DT	denotes	a
T15042	27235-27241	NN	denotes	number
T15041	27222-27226	RB	denotes	only
T15040	27264-27270	VBN	denotes	tested
T15039	27216-27221	IN	denotes	While
T15038	27215-27412	sentence	denotes	While only a small number of CSS mice have been tested for the arterial occlusion, the results suggest that interaction of the genes on chromosome 5 and 17 also determines arterial occlusion time.
T15037	27214-27215	.	denotes	.
T15036	27211-27214	NNS	denotes	min
T15035	27208-27210	CD	denotes	30
T15034	27205-27207	IN	denotes	by
T15033	27193-27196	RB	denotes	not
T15032	27189-27192	VBD	denotes	did
T15031	27180-27183	CD	denotes	two
T15030	27174-27179	JJ	denotes	other
T15029	27184-27188	NNS	denotes	mice
T15028	27170-27173	DT	denotes	the
T15027	27168-27169	:	denotes	;
T15026	27165-27168	NNS	denotes	min
T15025	27162-27164	CD	denotes	30
T15024	27159-27161	IN	denotes	by
T15023	27197-27204	VB	denotes	occlude
T15022	27146-27149	VBD	denotes	had
T15021	27139-27145	VBN	denotes	tested
T15020	27128-27133	CD	denotes	three
T15019	27125-27127	CC	denotes	or
T15018	27121-27124	CD	denotes	one
T15017	27134-27138	NNS	denotes	mice
T15016	27116-27120	RB	denotes	only
T15015	27114-27116	,	denotes	,
T15014	27107-27109	CD	denotes	17
T15013	27106-27107	HYPH	denotes	-
T15012	27103-27106	NN	denotes	CSS
T15011	27101-27102	SYM	denotes	×
T15010	27099-27100	CD	denotes	5
T15009	27098-27099	HYPH	denotes	-
T15008	27095-27098	NN	denotes	CSS
T15007	27110-27114	NNS	denotes	mice
T15006	27083-27094	JJ	denotes	heterosomic
T15005	27076-27082	JJ	denotes	double
T15004	27150-27158	VBN	denotes	occluded
T15003	27073-27075	IN	denotes	In
T15002	27072-27215	sentence	denotes	In double heterosomic CSS-5 × CSS-17 mice, only one or three mice tested had occluded by 30 min; the other two mice did not occlude by 30 min.
T15001	27071-27072	.	denotes	.
T15000	27064-27071	NNS	denotes	strains
T14999	27061-27062	HYPH	denotes	/
T14998	27060-27061	NN	denotes	A
T14997	27062-27063	NN	denotes	J
T14996	27056-27059	DT	denotes	the
T14995	27053-27055	CC	denotes	or
T14994	27047-27048	HYPH	denotes	-
T14993	27048-27052	NN	denotes	17F1
T14992	27044-27047	NN	denotes	CSS
T14991	27040-27043	CC	denotes	and
T14990	27035-27036	HYPH	denotes	-
T14989	27032-27035	NN	denotes	CSS
T14988	27020-27031	JJ	denotes	heterosomic
T14987	27036-27039	NN	denotes	5F1
T14986	27016-27019	DT	denotes	the
T14985	27013-27015	CC	denotes	or
T14984	27005-27007	NN	denotes	B6
T14983	27001-27004	DT	denotes	the
T14982	27008-27012	NNS	denotes	mice
T14981	26994-27000	CC	denotes	either
T14980	26989-26993	IN	denotes	than
T14979	26982-26988	JJR	denotes	higher
T14978	26976-26981	NNS	denotes	times
T14977	26966-26975	NN	denotes	occlusion
T14976	26962-26965	VBD	denotes	had
T14975	26951-26953	CD	denotes	17
T14974	26950-26951	HYPH	denotes	-
T14973	26947-26950	NN	denotes	CSS
T14972	26945-26946	SYM	denotes	×
T14971	26943-26944	CD	denotes	5
T14970	26942-26943	HYPH	denotes	-
T14969	26939-26942	NN	denotes	CSS
T14968	26927-26938	JJ	denotes	heterosomic
T14967	26920-26926	RB	denotes	doubly
T14966	26954-26961	NN	denotes	progeny
T14965	26916-26919	DT	denotes	the
T14964	26912-26915	CC	denotes	but
T14963	26910-26912	,	denotes	,
T14962	26903-26905	NN	denotes	B6
T14961	26906-26910	NNS	denotes	mice
T14960	26899-26902	DT	denotes	the
T14959	26896-26898	IN	denotes	to
T14958	26888-26895	JJ	denotes	similar
T14957	26882-26887	NNS	denotes	times
T14956	26872-26881	NN	denotes	occlusion
T14955	26865-26867	CD	denotes	17
T14954	26864-26865	HYPH	denotes	-
T14953	26861-26864	NN	denotes	CSS
T14952	26857-26860	CC	denotes	and
T14951	26855-26856	CD	denotes	5
T14950	26854-26855	HYPH	denotes	-
T14949	26868-26871	VBD	denotes	had
T14948	26851-26854	NN	denotes	CSS
T14947	26847-26850	DT	denotes	The
T14946	26846-27072	sentence	denotes	The CSS-5 and CSS-17 had occlusion times similar to the B6 mice, but the doubly heterosomic CSS-5 × CSS-17 progeny had occlusion times higher than either the B6 mice or the heterosomic CSS-5F1 and CSS-17F1 or the A/J strains.
T14945	26845-26846	.	denotes	.
T14944	26844-26845	-RRB-	denotes	)
T14943	26843-26844	CD	denotes	7
T14942	26836-26842	NN	denotes	Figure
T14941	26835-26836	-LRB-	denotes	(
T14940	26822-26827	NN	denotes	FeCl3
T14939	26828-26834	NN	denotes	injury
T14938	26818-26821	DT	denotes	the
T14937	26812-26817	IN	denotes	after
T14936	26802-26811	NN	denotes	occlusion
T14935	26793-26801	JJ	denotes	arterial
T14934	26789-26792	IN	denotes	for
T14933	26777-26781	VBD	denotes	were
T14932	26758-26768	VBN	denotes	identified
T14931	26769-26776	NNS	denotes	strains
T14930	26754-26757	DT	denotes	the
T14929	26782-26788	VBN	denotes	tested
T14928	26741-26753	RB	denotes	subsequently
T14927	26737-26740	CC	denotes	and
T14926	26735-26737	,	denotes	,
T14925	26724-26727	NN	denotes	CSS
T14924	26721-26723	CD	denotes	21
T14923	26728-26735	NNS	denotes	strains
T14922	26717-26720	DT	denotes	the
T14921	26714-26716	IN	denotes	of
T14920	26704-26713	NN	denotes	screening
T14919	26700-26703	DT	denotes	the
T14918	26688-26699	VBD	denotes	facilitated
T14917	26684-26687	CC	denotes	and
T14916	26678-26683	JJ	denotes	rapid
T14915	26674-26677	VBD	denotes	was
T14914	26659-26667	NN	denotes	bleeding
T14913	26654-26658	NN	denotes	tail
T14912	26668-26673	NN	denotes	assay
T14911	26650-26653	DT	denotes	The
T14910	26649-26846	sentence	denotes	The tail bleeding assay was rapid and facilitated the screening of the 21 CSS strains, and subsequently the identified strains were tested for arterial occlusion after the FeCl3 injury (Figure 7).
T14909	26640-26649	NN	denotes	formation
T14908	26631-26639	NN	denotes	thrombus
T14907	26622-26630	JJ	denotes	arterial
T14906	26618-26621	IN	denotes	for
T14905	26614-26617	NN	denotes	CSS
T14904	26611-26613	IN	denotes	of
T14903	26598-26610	NNS	denotes	Interactions
T14460	25648-25649	HYPH	denotes	-
T14459	25645-25648	NN	denotes	CSS
T14458	25643-25644	SYM	denotes	×
T14457	25641-25642	CD	denotes	5
T14456	25640-25641	HYPH	denotes	-
T14455	25637-25640	NN	denotes	CSS
T14454	25671-25678	NNS	denotes	strains
T14453	25633-25636	DT	denotes	The
T14452	25632-25731	sentence	denotes	The CSS-5 × CSS-17 double heterosomic strains had values similar to the B6 and A/J parent strains.
T14451	25631-25632	.	denotes	.
T14450	25629-25631	CD	denotes	17
T14449	25628-25629	HYPH	denotes	-
T14448	25625-25628	NN	denotes	CSS
T14447	25621-25624	CC	denotes	and
T14446	25619-25620	CD	denotes	5
T14445	25618-25619	HYPH	denotes	-
T14444	25603-25614	JJ	denotes	heterosomic
T14443	25599-25602	CC	denotes	and
T14442	25589-25598	JJ	denotes	homosomic
T14441	25615-25618	NN	denotes	CSS
T14440	25585-25588	DT	denotes	the
T14439	25582-25584	IN	denotes	in
T14438	25574-25581	JJ	denotes	similar
T14437	25562-25568	NNS	denotes	values
T14436	25558-25561	DT	denotes	the
T14435	25569-25573	VBD	denotes	were
T14434	25553-25557	IN	denotes	that
T14433	25548-25552	NN	denotes	fact
T14432	25544-25547	DT	denotes	the
T14431	25541-25543	IN	denotes	to
T14127	24459-24462	NN	denotes	CSS
T14126	24457-24459	,	denotes	,
T14125	24456-24457	-RRB-	denotes	)
T14124	24455-24456	CD	denotes	1
T14123	24454-24455	HYPH	denotes	-
T14122	24451-24454	NN	denotes	PAI
T14121	24450-24451	-LRB-	denotes	(
T14120	24448-24449	CD	denotes	5
T14119	24447-24448	HYPH	denotes	-
T14118	24444-24447	NN	denotes	CSS
T14117	24432-24443	NNS	denotes	chromosomes
T14116	24429-24431	IN	denotes	on
T14115	24411-24414	NN	denotes	Plg
T14114	24415-24421	NN	denotes	system
T14113	24407-24410	DT	denotes	the
T14112	24404-24406	IN	denotes	of
T14111	24422-24428	VBP	denotes	reside
T14110	24393-24403	NNS	denotes	Components
T14109	24392-24501	sentence	denotes	Components of the Plg system reside on chromosomes CSS-5 (PAI-1), CSS-11 (α2-antiplasmin), and CSS-17 (Plg).
T14108	24384-24392	NN	denotes	activity
T14107	24380-24383	CC	denotes	and
T14106	24372-24379	NN	denotes	antigen
T14105	24370-24371	CD	denotes	1
T14104	24369-24370	HYPH	denotes	-
T14103	24366-24369	NN	denotes	PAI
T14102	24362-24365	IN	denotes	for
T14101	24358-24361	NN	denotes	CSS
T14100	24355-24357	IN	denotes	of
T14099	24342-24354	NNS	denotes	Interactions
T14430	25537-25540	IN	denotes	due
T14429	25522-25530	JJ	denotes	dominant
T14428	25531-25536	NN	denotes	trait
T14427	25520-25521	DT	denotes	a
T14426	25516-25519	VBD	denotes	was
T14425	25506-25507	CD	denotes	1
T14424	25505-25506	HYPH	denotes	-
T14423	25502-25505	NN	denotes	PAI
T14422	25494-25501	VBN	denotes	reduced
T14421	25508-25515	NN	denotes	antigen
T14420	25490-25493	DT	denotes	The
T14419	25489-25632	sentence	denotes	The reduced PAI-1 antigen was a dominant trait due to the fact that the values were similar in the homosomic and heterosomic CSS-5 and CSS-17.
T14418	25488-25489	.	denotes	.
T14417	25484-25488	NNS	denotes	mice
T14416	25481-25483	NN	denotes	B6
T14415	25478-25480	IN	denotes	to
T14414	25469-25477	VBN	denotes	compared
T14413	25464-25468	WRB	denotes	when
T14412	25454-25455	CD	denotes	1
T14411	25453-25454	HYPH	denotes	-
T14410	25450-25453	NN	denotes	PAI
T14409	25456-25463	NN	denotes	antigen
T14408	25442-25449	VBN	denotes	reduced
T14407	25428-25437	RB	denotes	generally
T14406	25422-25423	HYPH	denotes	-
T14405	25423-25427	NN	denotes	17F1
T14404	25419-25422	NN	denotes	CSS
T14403	25415-25418	CC	denotes	and
T14402	25413-25415	,	denotes	,
T14401	25409-25410	HYPH	denotes	-
T14400	25410-25413	NN	denotes	5F1
T14399	25406-25409	NN	denotes	CSS
T14398	25404-25406	,	denotes	,
T14397	25402-25404	CD	denotes	17
T14396	25401-25402	HYPH	denotes	-
T14395	25398-25401	NN	denotes	CSS
T14394	25396-25398	,	denotes	,
T14393	25395-25396	CD	denotes	5
T14392	25394-25395	HYPH	denotes	-
T14391	25438-25441	VBD	denotes	had
T14390	25391-25394	NN	denotes	CSS
T14389	25390-25489	sentence	denotes	CSS-5, CSS-17, CSS-5F1, and CSS-17F1 generally had reduced PAI-1 antigen when compared to B6 mice.
T14388	25389-25390	.	denotes	.
T14387	25387-25389	CD	denotes	17
T14386	25385-25386	SYM	denotes	×
T14385	25383-25384	CD	denotes	5
T14384	25382-25383	HYPH	denotes	-
T14383	25379-25382	NN	denotes	CSS
T14382	25377-25379	,	denotes	,
T14381	25367-25377	JJ	denotes	hetersomic
T14380	25360-25366	JJ	denotes	double
T14379	25356-25359	CC	denotes	and
T14378	25354-25356	,	denotes	,
T14377	25349-25350	HYPH	denotes	-
T14376	25350-25354	NN	denotes	17F1
T14375	25346-25349	NN	denotes	CSS
T14374	25344-25346	,	denotes	,
T14373	25340-25341	HYPH	denotes	-
T14372	25341-25344	NN	denotes	5F1
T14371	25337-25340	NN	denotes	CSS
T14370	25335-25337	,	denotes	,
T14369	25324-25335	JJ	denotes	heterosomic
T14368	25320-25323	DT	denotes	the
T14367	25318-25320	,	denotes	,
T14366	25317-25318	-RRB-	denotes	)
T14365	25316-25317	CD	denotes	6
T14364	25309-25315	NN	denotes	Figure
T14363	25308-25309	-LRB-	denotes	(
T14362	25305-25307	CD	denotes	17
T14361	25304-25305	HYPH	denotes	-
T14360	25301-25304	NN	denotes	CSS
T14359	25297-25300	CC	denotes	and
T14358	25295-25297	,	denotes	,
T14357	25293-25295	CD	denotes	11
T14356	25292-25293	HYPH	denotes	-
T14355	25289-25292	NN	denotes	CSS
T14354	25287-25289	,	denotes	,
T14353	25286-25287	CD	denotes	5
T14352	25285-25286	HYPH	denotes	-
T14351	25282-25285	NN	denotes	CSS
T14350	25280-25282	,	denotes	,
T14349	25264-25274	NN	denotes	rebleeding
T14348	25275-25280	NNS	denotes	times
T14347	25254-25263	VBN	denotes	increased
T14346	25249-25253	IN	denotes	with
T14345	25245-25248	NNS	denotes	CSS
T14344	25241-25244	DT	denotes	the
T14343	25238-25240	IN	denotes	in
T14342	25222-25226	VBD	denotes	were
T14341	25213-25221	NN	denotes	activity
T14340	25209-25212	CC	denotes	and
T14339	25201-25208	NN	denotes	antigen
T14338	25199-25200	CD	denotes	1
T14337	25198-25199	HYPH	denotes	-
T14336	25227-25237	VBN	denotes	determined
T14335	25195-25198	NN	denotes	PAI
T14334	25194-25390	sentence	denotes	PAI-1 antigen and activity were determined in the CSS with increased rebleeding times, CSS-5, CSS-11, and CSS-17 (Figure 6), the heterosomic, CSS-5F1, CSS-17F1, and double hetersomic, CSS-5 × 17.
T14333	25193-25194	.	denotes	.
T14332	25186-25188	NN	denotes	B6
T14331	25189-25193	NNS	denotes	mice
T14330	25182-25185	DT	denotes	the
T14329	25179-25181	IN	denotes	to
T14328	25170-25178	VBN	denotes	compared
T14327	25162-25164	CD	denotes	17
T14326	25160-25161	SYM	denotes	×
T14325	25158-25159	CD	denotes	5
T14324	25157-25158	HYPH	denotes	-
T14323	25154-25157	NN	denotes	CSS
T14322	25151-25153	CC	denotes	or
T14321	25148-25150	CD	denotes	17
T14317	25141-25143	IN	denotes	in
T14316	25131-25140	JJ	denotes	different
T14315	25127-25130	RB	denotes	not
T14314	25123-25126	CC	denotes	but
T14313	25121-25123	,	denotes	,
T14312	25120-25121	-RRB-	denotes	)
T14311	25117-25118	SYM	denotes	=
T14310	25119-25120	CD	denotes	8
T14309	25115-25116	NN	denotes	n
T14308	25113-25115	,	denotes	,
T14307	25110-25111	SYM	denotes	±
T14306	25106-25109	CD	denotes	201
T14305	25112-25113	CD	denotes	6
T14304	25105-25106	-LRB-	denotes	(
T14303	25102-25104	CD	denotes	11
T14302	25101-25102	HYPH	denotes	-
T14301	25098-25101	NN	denotes	CSS
T14300	25094-25097	DT	denotes	the
T14299	25091-25093	IN	denotes	in
T14298	25082-25083	-RRB-	denotes	)
T14297	25076-25077	SYM	denotes	<
T14296	25074-25075	NN	denotes	P
T14295	25078-25082	CD	denotes	0.05
T14294	25073-25074	-LRB-	denotes	(
T14293	25084-25090	JJR	denotes	higher
T14292	25059-25072	RB	denotes	significantly
T14291	25057-25059	,	denotes	,
T14290	25056-25057	-RRB-	denotes	)
T14289	25053-25054	SYM	denotes	=
T14288	25055-25056	CD	denotes	5
T14287	25051-25052	NN	denotes	n
T14286	25049-25051	,	denotes	,
T14285	25047-25049	NN	denotes	mL
T14284	25046-25047	SYM	denotes	/
T14283	25040-25041	SYM	denotes	±
T14282	25042-25043	CD	denotes	4
T14281	25036-25039	CD	denotes	142
T14280	25044-25046	NNS	denotes	μg
T14279	25035-25036	-LRB-	denotes	(
T14278	25028-25029	CD	denotes	5
T14277	25027-25028	HYPH	denotes	-
T14276	25030-25034	NNS	denotes	mice
T14275	25024-25027	NN	denotes	CSS
T14274	25021-25023	IN	denotes	in
T14273	25011-25012	-RRB-	denotes	)
T14272	25005-25006	SYM	denotes	<
T14271	25003-25004	SYM	denotes	=
T14270	25001-25002	NN	denotes	P
T14269	25007-25011	CD	denotes	0.01
T14268	25000-25001	-LRB-	denotes	(
T14267	25013-25020	JJ	denotes	reduced
T14266	24986-24999	RB	denotes	significantly
T14265	24982-24985	VBD	denotes	was
T14264	24969-24970	HYPH	denotes	-
T14263	24970-24981	NN	denotes	antiplasmin
T14262	24967-24969	NN	denotes	α2
T14261	24966-25194	sentence	denotes	α2-antiplasmin was significantly (P = < 0.01) reduced in CSS-5 mice (142 ± 4 μg/mL, n = 5), significantly (P < 0.05) higher in the CSS-11 (201 ± 6, n = 8), but not different in CSS-17 or CSS-5 × 17 mice compared to the B6 mice.
T14260	24965-24966	.	denotes	.
T14259	24958-24960	NN	denotes	B6
T14258	24961-24965	NNS	denotes	mice
T14257	24954-24957	DT	denotes	the
T14256	24951-24953	IN	denotes	to
T14255	24942-24950	VBN	denotes	compared
T14254	24931-24933	CD	denotes	17
T14253	24930-24931	HYPH	denotes	-
T14252	24927-24930	NN	denotes	CSS
T14251	24924-24926	CC	denotes	or
T14250	24922-24923	CD	denotes	5
T14249	24921-24922	HYPH	denotes	-
T14248	24918-24921	NN	denotes	CSS
T14247	24934-24941	NNS	denotes	strains
T14246	24914-24917	DT	denotes	the
T14245	24911-24913	IN	denotes	in
T14244	24901-24910	JJ	denotes	different
T14243	24897-24900	RB	denotes	not
T14242	24893-24896	VBD	denotes	was
T14241	24884-24892	NN	denotes	activity
T14240	24871-24883	JJ	denotes	Fibrinolytic
T14239	24870-24966	sentence	denotes	Fibrinolytic activity was not different in the CSS-5 or CSS-17 strains compared to the B6 mice.
T14238	24869-24870	.	denotes	.
T14237	24862-24864	NN	denotes	B6
T14236	24865-24869	NNS	denotes	mice
T14235	24858-24861	DT	denotes	the
T14234	24854-24857	IN	denotes	for
T14233	24847-24853	NNS	denotes	values
T14232	24844-24846	IN	denotes	to
T14231	24836-24843	JJ	denotes	similar
T14230	24820-24823	NN	denotes	Plg
T14229	24824-24831	NN	denotes	antigen
T14228	24816-24819	DT	denotes	the
T14227	24814-24816	,	denotes	,
T14226	24812-24814	CD	denotes	17
T14225	24810-24811	SYM	denotes	×
T14224	24808-24809	CD	denotes	5
T14223	24807-24808	HYPH	denotes	-
T14222	24804-24807	NN	denotes	CSS
T14221	24800-24803	CC	denotes	and
T14220	24798-24799	CD	denotes	5
T14219	24797-24798	HYPH	denotes	-
T14218	24794-24797	NN	denotes	CSS
T14217	24832-24835	VBD	denotes	was
T14216	24790-24793	IN	denotes	for
T14215	24786-24789	CC	denotes	but
T14214	24784-24786	,	denotes	,
T14213	24777-24779	NN	denotes	B6
T14212	24780-24784	NNS	denotes	mice
T14211	24773-24776	DT	denotes	the
T14210	24770-24772	IN	denotes	to
T14209	24761-24769	VBN	denotes	compared
T14208	24756-24760	WRB	denotes	when
T14207	24754-24755	-RRB-	denotes	)
T14206	24750-24751	SYM	denotes	=
T14205	24752-24754	CD	denotes	12
T14204	24748-24749	NN	denotes	n
T14203	24746-24748	,	denotes	,
T14202	24743-24744	SYM	denotes	±
T14201	24739-24742	CD	denotes	152
T14200	24745-24746	CD	denotes	6
T14199	24738-24739	-LRB-	denotes	(
T14198	24726-24727	-RRB-	denotes	)
T14197	24719-24720	SYM	denotes	=
T14196	24717-24718	NN	denotes	P
T14195	24721-24726	CD	denotes	0.015
T14194	24716-24717	-LRB-	denotes	(
T14193	24728-24737	JJ	denotes	increased
T14192	24702-24715	RB	denotes	significantly
T14191	24697-24701	RB	denotes	also
T14190	24681-24684	NN	denotes	Plg
T14189	24685-24692	NN	denotes	antigen
T14188	24677-24680	DT	denotes	the
T14187	24675-24677	,	denotes	,
T14186	24668-24670	CD	denotes	17
T14185	24667-24668	HYPH	denotes	-
T14184	24671-24675	NNS	denotes	mice
T14183	24664-24667	NN	denotes	CSS
T14182	24693-24696	VBD	denotes	was
T14181	24661-24663	IN	denotes	In
T14180	24660-24870	sentence	denotes	In CSS-17 mice, the Plg antigen was also significantly (P = 0.015) increased (152 ± 6, n = 12) when compared to the B6 mice, but for CSS-5 and CSS-5 × 17, the Plg antigen was similar to values for the B6 mice.
T14179	24659-24660	.	denotes	.
T14178	24655-24659	NNS	denotes	mice
T14177	24652-24654	NN	denotes	B6
T14176	24649-24651	IN	denotes	to
T14175	24640-24648	VBN	denotes	compared
T14174	24635-24639	WRB	denotes	when
T14173	24624-24634	NN	denotes	fibrinogen
T14172	24620-24623	CC	denotes	and
T14171	24609-24610	CD	denotes	1
T14170	24608-24609	HYPH	denotes	-
T14169	24611-24619	NN	denotes	activity
T14168	24605-24608	NN	denotes	PAI
T14167	24603-24605	,	denotes	,
T14166	24591-24592	HYPH	denotes	-
T14165	24592-24603	NN	denotes	antiplasmin
T14164	24589-24591	NN	denotes	α2
T14163	24587-24589	,	denotes	,
T14162	24579-24587	NN	denotes	activity
T14161	24566-24578	JJ	denotes	fibrinolytic
T14160	24564-24566	,	denotes	,
T14159	24553-24556	NN	denotes	Plg
T14158	24557-24564	NN	denotes	antigen
T14157	24543-24552	VBN	denotes	increased
T14156	24531-24532	HYPH	denotes	/
T14155	24532-24533	NN	denotes	J
T14154	24530-24531	NN	denotes	A
T14153	24534-24538	NNS	denotes	mice
T14152	24526-24529	DT	denotes	the
T14151	24524-24526	,	denotes	,
T14150	24523-24524	CD	denotes	2
T14149	24517-24522	NN	denotes	Table
T14148	24514-24516	IN	denotes	in
T14147	24539-24542	VBD	denotes	had
T14146	24505-24513	VBN	denotes	reported
T14145	24502-24504	IN	denotes	As
T14144	24501-24660	sentence	denotes	As reported in Table 2, the A/J mice had increased Plg antigen, fibrinolytic activity, α2-antiplasmin, PAI-1 activity and fibrinogen when compared to B6 mice.
T14143	24500-24501	.	denotes	.
T14142	24499-24500	-RRB-	denotes	)
T14141	24496-24499	NN	denotes	Plg
T14140	24495-24496	-LRB-	denotes	(
T14139	24492-24494	CD	denotes	17
T14138	24491-24492	HYPH	denotes	-
T14137	24488-24491	NN	denotes	CSS
T14136	24484-24487	CC	denotes	and
T14135	24482-24484	,	denotes	,
T14134	24481-24482	-RRB-	denotes	)
T14133	24469-24470	HYPH	denotes	-
T14132	24470-24481	NN	denotes	antiplasmin
T14131	24467-24469	NN	denotes	α2
T14130	24466-24467	-LRB-	denotes	(
T14129	24463-24465	CD	denotes	11
T14128	24462-24463	HYPH	denotes	-
T14320	25147-25148	HYPH	denotes	-
T14319	25165-25169	NNS	denotes	mice
T14318	25144-25147	NN	denotes	CSS
T13199	23790-23791	.	denotes	.
T13198	23781-23790	NN	denotes	phenotype
T13197	23777-23780	DT	denotes	the
T13196	23769-23776	VB	denotes	produce
T13195	23766-23768	TO	denotes	to
T13194	23749-23753	VBD	denotes	were
T13193	23734-23735	HYPH	denotes	/
T13192	23735-23736	NN	denotes	J
T13191	23733-23734	NN	denotes	A
T13190	23737-23748	NNS	denotes	chromosomes
T13189	23729-23732	DT	denotes	the
T13188	23726-23728	IN	denotes	on
T13187	23719-23725	NNS	denotes	traits
T13186	23754-23765	VBG	denotes	interacting
T13185	23714-23718	IN	denotes	that
T13184	23704-23713	VBD	denotes	suggested
T13183	23699-23703	DT	denotes	This
T13182	23698-23791	sentence	denotes	This suggested that traits on the A/J chromosomes were interacting to produce the phenotype.
T13181	23697-23698	.	denotes	.
T13180	23695-23696	HYPH	denotes	/
T13179	23696-23697	NN	denotes	J
T13178	23694-23695	NN	denotes	A
T13177	23691-23693	IN	denotes	to
T13176	23683-23690	JJ	denotes	similar
T13175	23679-23682	RB	denotes	now
T13174	23665-23674	NN	denotes	phenotype
T13173	23661-23664	DT	denotes	the
T13172	23659-23661	,	denotes	,
T13171	23657-23659	CD	denotes	17
T13170	23656-23657	HYPH	denotes	-
T13169	23653-23656	NN	denotes	CSS
T13168	23651-23652	SYM	denotes	×
T13167	23649-23650	CD	denotes	5
T13166	23648-23649	HYPH	denotes	-
T13165	23645-23648	NN	denotes	CSS
T13164	23641-23644	DT	denotes	the
T13163	23638-23640	IN	denotes	of
T13162	23630-23637	NN	denotes	progeny
T13161	23626-23629	DT	denotes	the
T13160	23623-23625	IN	denotes	in
T13159	23620-23622	CD	denotes	17
T13158	23616-23619	CC	denotes	and
T13157	23614-23615	CD	denotes	5
T13156	23611-23613	IN	denotes	of
T13155	23587-23598	JJ	denotes	heterosomic
T13154	23599-23610	NNS	denotes	chromosomes
T13153	23583-23586	DT	denotes	the
T13152	23575-23582	IN	denotes	despite
T13151	23573-23575	,	denotes	,
T13150	23675-23678	VBD	denotes	was
T13149	23569-23573	RB	denotes	Thus
T13148	23568-23698	sentence	denotes	Thus, despite the heterosomic chromosomes of 5 and 17 in the progeny of the CSS-5 × CSS-17, the phenotype was now similar to A/J.
T13147	23567-23568	.	denotes	.
T13146	23548-23559	JJ	denotes	heterosomic
T13145	23541-23547	JJ	denotes	double
T13144	23560-23567	NNS	denotes	strains
T13143	23535-23540	DT	denotes	these
T13142	23532-23534	IN	denotes	of
T13141	23524-23531	NN	denotes	progeny
T13140	23520-23523	DT	denotes	the
T13139	23517-23519	IN	denotes	in
T13138	23504-23505	HYPH	denotes	/
T13137	23505-23506	NN	denotes	J
T13136	23503-23504	NN	denotes	A
T13135	23507-23516	NN	denotes	phenotype
T13134	23499-23502	DT	denotes	the
T13133	23496-23498	IN	denotes	of
T13132	23487-23495	NN	denotes	recovery
T13131	23483-23486	DT	denotes	the
T13130	23480-23482	IN	denotes	in
T13129	23469-23470	-RRB-	denotes	)
T13128	23467-23469	CD	denotes	17
T13127	23466-23467	HYPH	denotes	-
T13126	23463-23466	NN	denotes	CSS
T13125	23461-23462	SYM	denotes	×
T13124	23459-23460	CD	denotes	5
T13123	23458-23459	HYPH	denotes	-
T13122	23455-23458	NN	denotes	CSS
T13121	23454-23455	-LRB-	denotes	(
T13120	23451-23452	HYPH	denotes	/
T13119	23445-23451	NN	denotes	Chr17A
T13118	23444-23445	HYPH	denotes	-
T13117	23452-23453	NN	denotes	J
T13116	23442-23444	NN	denotes	B6
T13115	23440-23441	SYM	denotes	×
T13114	23437-23438	HYPH	denotes	/
T13113	23432-23437	NN	denotes	Chr5A
T13112	23431-23432	HYPH	denotes	-
T13111	23438-23439	NN	denotes	J
T13110	23429-23431	NN	denotes	B6
T13109	23427-23429	,	denotes	,
T13108	23422-23427	NN	denotes	cross
T13107	23418-23421	DT	denotes	the
T13106	23415-23417	IN	denotes	of
T13105	23407-23414	NN	denotes	progeny
T13104	23403-23406	DT	denotes	the
T13103	23400-23402	IN	denotes	in
T13102	23389-23399	NN	denotes	rebleeding
T13101	23385-23388	CC	denotes	and
T13100	23471-23479	VBD	denotes	resulted
T13099	23376-23384	NN	denotes	Bleeding
T13098	23375-23568	sentence	denotes	Bleeding and rebleeding in the progeny of the cross, B6-Chr5A/J × B6-Chr17A/J (CSS-5 × CSS-17) resulted in the recovery of the A/J phenotype in the progeny of these double heterosomic strains.
T13097	23374-23375	.	denotes	.
T13096	23365-23374	JJ	denotes	recessive
T13095	23362-23364	VBZ	denotes	is
T13094	23353-23354	HYPH	denotes	/
T13093	23354-23355	NN	denotes	J
T13092	23352-23353	NN	denotes	A
T13091	23356-23361	NN	denotes	trait
T13090	23348-23351	DT	denotes	the
T13089	23337-23347	VBG	denotes	suggesting
T13088	23335-23337	,	denotes	,
T13087	23331-23335	NNS	denotes	mice
T13086	23328-23329	HYPH	denotes	/
T13064	23236-23239	DT	denotes	The
T13063	23235-23375	sentence	denotes	The rebleeding values for CSS-5F1 and CSS-17F1 mice were similar to the B6 rather than the A/J mice, suggesting the A/J trait is recessive.
T13062	23234-23235	.	denotes	.
T13061	23233-23234	-RRB-	denotes	)
T13060	23232-23233	CD	denotes	5
T13059	23225-23231	NN	denotes	Figure
T13058	23224-23225	-LRB-	denotes	(
T13057	23212-23213	-RRB-	denotes	)
T13056	23210-23212	CD	denotes	17
T13055	23209-23210	HYPH	denotes	-
T13054	23203-23209	NN	denotes	B6xCSS
T13053	23202-23203	-LRB-	denotes	(
T13052	23199-23201	CD	denotes	17
T13051	23198-23199	HYPH	denotes	-
T13050	23213-23215	NN	denotes	F1
T13049	23195-23198	NN	denotes	CSS
T13048	23191-23194	CC	denotes	and
T13047	23187-23188	-RRB-	denotes	)
T13046	23186-23187	CD	denotes	5
T13045	23185-23186	HYPH	denotes	-
T13044	23179-23185	NN	denotes	B6xCSS
T13043	23178-23179	-LRB-	denotes	(
T13042	23176-23178	,	denotes	,
T13041	23175-23176	CD	denotes	5
T13040	23174-23175	HYPH	denotes	-
T13039	23188-23190	NN	denotes	F1
T13038	23171-23174	NN	denotes	CSS
T13037	23216-23223	NNS	denotes	strains
T12963	22474-22476	,	denotes	,
T12962	22471-22473	CD	denotes	60
T12961	22470-22471	:	denotes	–
T12960	22469-22470	CD	denotes	5
T12959	22468-22469	HYPH	denotes	-
T12958	22473-22474	NN	denotes	%
T12957	22465-22468	NN	denotes	CSS
T12956	22463-22465	:	denotes	:
T12955	22450-22455	CD	denotes	three
T12954	22456-22463	NNS	denotes	strains
T12953	22446-22449	DT	denotes	the
T12952	22442-22445	IN	denotes	for
T12951	22425-22430	NN	denotes	value
T12950	22420-22424	DT	denotes	this
T12949	22415-22419	IN	denotes	with
T12948	22410-22414	NNS	denotes	mice
T12947	22407-22409	IN	denotes	of
T12946	22431-22441	VBN	denotes	determined
T12945	22396-22406	NN	denotes	percentage
T12944	22392-22395	DT	denotes	the
T12943	22388-22391	CC	denotes	and
T12942	22386-22388	,	denotes	,
T12941	22383-22386	NN	denotes	sec
T12940	22379-22382	CD	denotes	600
T12939	22376-22378	IN	denotes	at
T12938	22364-22367	VBD	denotes	was
T12937	22368-22375	VBN	denotes	stopped
T12936	22348-22358	NN	denotes	rebleeding
T12935	22359-22363	NN	denotes	time
T12934	22344-22347	DT	denotes	The
T12933	22343-22503	sentence	denotes	The rebleeding time was stopped at 600 sec, and the percentage of mice with this value determined for the three strains: CSS-5–60%, CSS-11–60% and CSS-A17–46%.
T12932	22342-22343	.	denotes	.
T12931	22337-22342	CD	denotes	0.008
T12930	22335-22336	SYM	denotes	<
T12929	22333-22334	NN	denotes	P
T12928	22330-22332	IN	denotes	at
T12927	22317-22329	NN	denotes	significance
T12926	22304-22306	,	denotes	,
T12925	22303-22304	-RRB-	denotes	)
T12924	22302-22303	CD	denotes	5
T12923	22301-22302	HYPH	denotes	-
T12922	22298-22301	NN	denotes	CSS
T12921	22297-22298	-LRB-	denotes	(
T12920	22294-22295	HYPH	denotes	/
T12919	22295-22296	NN	denotes	J
T12918	22288-22289	HYPH	denotes	-
T12917	22289-22294	NN	denotes	Chr5A
T12916	22286-22288	NN	denotes	B6
T12915	22284-22286	,	denotes	,
T12914	22306-22316	VBN	denotes	approached
T12913	22278-22284	NN	denotes	strain
T12912	22270-22277	DT	denotes	Another
T12911	22269-22343	sentence	denotes	Another strain, B6-Chr5A/J (CSS-5), approached significance at P < 0.008.
T12910	22268-22269	.	denotes	.
T12909	22261-22262	HYPH	denotes	/
T12908	22262-22263	NN	denotes	J
T12907	22260-22261	NN	denotes	A
T12906	22264-22268	NNS	denotes	mice
T12905	22256-22259	DT	denotes	the
T12904	22251-22255	IN	denotes	from
T12903	22244-22250	NNS	denotes	values
T12902	22241-22243	IN	denotes	to
T12901	22233-22240	JJ	denotes	similar
T12900	22228-22232	VBD	denotes	were
T12899	22223-22227	WDT	denotes	that
T12898	22215-22217	NN	denotes	B6
T12897	22218-22222	NNS	denotes	mice
T12896	22211-22214	DT	denotes	the
T12895	22208-22210	IN	denotes	to
T12894	22199-22207	VBN	denotes	compared
T12893	22182-22192	NN	denotes	rebleeding
T12892	22193-22198	NNS	denotes	times
T12891	22173-22174	-RRB-	denotes	)
T12890	22166-22167	SYM	denotes	<
T12889	22164-22165	NN	denotes	P
T12888	22168-22173	CD	denotes	0.002
T12887	22163-22164	-LRB-	denotes	(
T12886	22175-22181	JJR	denotes	longer
T12885	22149-22162	RB	denotes	significantly
T12884	22143-22145	,	denotes	,
T12883	22142-22143	-RRB-	denotes	)
T12882	22140-22142	CD	denotes	17
T12881	22139-22140	HYPH	denotes	-
T12880	22136-22139	NN	denotes	CSS
T12879	22135-22136	-LRB-	denotes	(
T12878	22132-22133	HYPH	denotes	/
T12877	22133-22134	NN	denotes	J
T12876	22125-22126	HYPH	denotes	-
T12875	22126-22132	NN	denotes	Chr17A
T12874	22123-22125	NN	denotes	B6
T12873	22119-22122	CC	denotes	and
T12872	22117-22118	-RRB-	denotes	)
T12871	22115-22117	CD	denotes	11
T12870	22114-22115	HYPH	denotes	-
T12869	22111-22114	NN	denotes	CSS
T12868	22110-22111	-LRB-	denotes	(
T12867	22107-22108	HYPH	denotes	/
T12866	22108-22109	NN	denotes	J
T12865	22100-22101	HYPH	denotes	-
T12864	22101-22107	NN	denotes	Chr11A
T12863	22098-22100	NN	denotes	B6
T12862	22096-22098	,	denotes	,
T12861	22145-22148	VBD	denotes	had
T12860	22089-22096	NNS	denotes	strains
T12859	22085-22088	CD	denotes	two
T12858	22081-22084	CC	denotes	and
T12857	22073-22075	NN	denotes	B6
T12856	22076-22080	NNS	denotes	mice
T12855	22069-22072	DT	denotes	the
T12854	22066-22068	IN	denotes	to
T12853	22057-22065	VBN	denotes	compared
T12852	22049-22050	HYPH	denotes	/
T12851	22050-22051	NN	denotes	J
T12850	22048-22049	NN	denotes	A
T12849	22052-22056	NNS	denotes	mice
T13085	23327-23328	NN	denotes	A
T13084	23329-23330	NN	denotes	J
T13083	23323-23326	DT	denotes	the
T13082	23318-23322	IN	denotes	than
T13081	23311-23317	RB	denotes	rather
T13080	23308-23310	NN	denotes	B6
T13079	23304-23307	DT	denotes	the
T13078	23301-23303	IN	denotes	to
T13077	23293-23300	JJ	denotes	similar
T13076	23277-23278	HYPH	denotes	-
T13075	23278-23282	NN	denotes	17F1
T13074	23274-23277	NN	denotes	CSS
T13073	23270-23273	CC	denotes	and
T13072	23283-23287	NNS	denotes	mice
T13071	23265-23266	HYPH	denotes	-
T13070	23266-23269	NN	denotes	5F1
T13069	23262-23265	NN	denotes	CSS
T13068	23258-23261	IN	denotes	for
T13067	23288-23292	VBD	denotes	were
T13066	23240-23250	NN	denotes	rebleeding
T13065	23251-23257	NNS	denotes	values
T12809	21856-21858	IN	denotes	to
T12808	21847-21855	VBN	denotes	compared
T12807	21845-21846	-RRB-	denotes	)
T12806	21838-21845	NNS	denotes	seconds
T12805	21834-21835	SYM	denotes	–
T12804	21835-21837	CD	denotes	79
T12803	21832-21834	CD	denotes	49
T12802	21831-21832	-LRB-	denotes	(
T12801	21816-21824	NN	denotes	bleeding
T12800	21814-21815	-RRB-	denotes	)
T12799	21807-21808	SYM	denotes	<
T12798	21805-21806	NN	denotes	P
T12797	21809-21814	CD	denotes	0.002
T12796	21804-21805	-LRB-	denotes	(
T12795	21825-21830	NNS	denotes	times
T12794	21798-21803	JJR	denotes	lower
T12793	21792-21794	,	denotes	,
T12792	21790-21791	HYPH	denotes	/
T12791	21791-21792	NN	denotes	J
T12790	21788-21790	NN	denotes	YA
T12789	21784-21787	CC	denotes	and
T12788	21782-21784	,	denotes	,
T12787	21780-21782	CD	denotes	15
T12786	21778-21780	,	denotes	,
T12785	21776-21778	CD	denotes	14
T12784	21774-21776	,	denotes	,
T12783	21773-21774	CD	denotes	8
T12782	21771-21773	,	denotes	,
T12781	21770-21771	CD	denotes	6
T12780	21768-21770	,	denotes	,
T12779	21763-21764	HYPH	denotes	-
T12778	21764-21768	NN	denotes	Chr5
T12777	21761-21763	NN	denotes	B6
T12776	21759-21761	,	denotes	,
T12775	21752-21759	NNS	denotes	strains
T12774	21748-21751	DT	denotes	the
T12773	21745-21747	IN	denotes	of
T12772	21794-21797	VBD	denotes	had
T12771	21740-21744	NN	denotes	6six
T12770	21736-21739	CC	denotes	but
T12769	21734-21736	,	denotes	,
T12768	21725-21734	JJ	denotes	different
T12767	21721-21724	RB	denotes	not
T12766	21711-21715	NNS	denotes	mice
T12765	21708-21709	HYPH	denotes	/
T12764	21707-21708	NN	denotes	A
T12763	21709-21710	NN	denotes	J
T12762	21703-21706	DT	denotes	the
T12761	21699-21702	CC	denotes	and
T12760	21696-21698	NN	denotes	B6
T12759	21692-21695	DT	denotes	the
T12758	21688-21691	IN	denotes	for
T12757	21686-21687	-RRB-	denotes	)
T12756	21677-21683	NN	denotes	Figure
T12755	21684-21686	NN	denotes	4A
T12754	21676-21677	-LRB-	denotes	(
T12753	21716-21720	VBD	denotes	were
T12752	21661-21669	NN	denotes	bleeding
T12751	21670-21675	NNS	denotes	times
T12750	21657-21660	DT	denotes	The
T12749	21656-21895	sentence	denotes	The bleeding times (Figure 4A) for the B6 and the A/J mice were not different, but 6six of the strains, B6-Chr5, 6, 8, 14, 15, and YA/J, had lower (P < 0.002) bleeding times (49–79 seconds) compared to the value for the B6 mice (121 sec).
T12748	21655-21656	.	denotes	.
T12747	21642-21646	VBD	denotes	were
T12746	21638-21641	NN	denotes	CSS
T12745	21634-21637	DT	denotes	the
T12744	21632-21634	,	denotes	,
T12743	21622-21632	NN	denotes	thrombosis
T12742	21618-21621	CC	denotes	and
T12741	21607-21617	NN	denotes	hemostasis
T12740	21603-21606	IN	denotes	for
T12739	21586-21595	JJ	denotes	surrogate
T12738	21596-21602	NN	denotes	marker
T12737	21584-21585	DT	denotes	a
T12736	21581-21583	IN	denotes	as
T12735	21563-21564	HYPH	denotes	/
T12734	21555-21563	NN	denotes	bleeding
T12733	21564-21574	NN	denotes	rebleeding
T12732	21550-21554	NN	denotes	tail
T12731	21575-21580	NN	denotes	assay
T12730	21546-21549	DT	denotes	the
T12729	21647-21655	VBN	denotes	screened
T12728	21540-21545	VBG	denotes	Using
T12727	21539-21656	sentence	denotes	Using the tail bleeding/rebleeding assay as a surrogate marker for hemostasis and thrombosis, the CSS were screened.
T12726	21536-21539	NN	denotes	CSS
T12725	21533-21535	IN	denotes	in
T12724	21522-21532	NN	denotes	rebleeding
T11834	20744-20745	-RRB-	denotes	)
T11833	20735-20738	RB	denotes	not
T11832	20730-20734	NNS	denotes	data
T11831	20739-20744	VBN	denotes	shown
T11830	20729-20730	-LRB-	denotes	(
T11829	20721-20723	NN	denotes	B6
T11828	20724-20728	NNS	denotes	mice
T11827	20717-20720	DT	denotes	the
T11826	20714-20716	IN	denotes	to
T11825	20705-20713	VBN	denotes	compared
T11824	20690-20694	RB	denotes	also
T11823	20687-20689	VBZ	denotes	is
T11822	20679-20680	HYPH	denotes	/
T11821	20680-20681	NN	denotes	J
T11820	20678-20679	NN	denotes	A
T11819	20682-20686	NNS	denotes	mice
T11818	20674-20677	DT	denotes	the
T11817	20671-20673	IN	denotes	in
T11816	20664-20670	NN	denotes	tissue
T11815	20656-20663	NN	denotes	adipose
T11814	20653-20655	IN	denotes	in
T11813	20645-20652	NNS	denotes	vessels
T11812	20642-20644	IN	denotes	in
T11811	20695-20704	VBN	denotes	increased
T11810	20633-20641	NN	denotes	Collagen
T11809	20632-20746	sentence	denotes	Collagen in vessels in adipose tissue in the A/J mice is also increased compared to the B6 mice (data not shown).
T11808	20631-20632	.	denotes	.
T11807	20630-20631	-RRB-	denotes	)
T11806	20624-20625	SYM	denotes	<
T11805	20622-20623	NN	denotes	P
T11804	20626-20630	CD	denotes	0.05
T11803	20621-20622	-LRB-	denotes	(
T11802	20613-20615	NN	denotes	B6
T11801	20616-20620	NNS	denotes	mice
T11800	20609-20612	DT	denotes	the
T12839	21983-21993	NN	denotes	initiation
T12838	21979-21982	CC	denotes	and
T12837	21969-21978	NN	denotes	cessation
T12836	21960-21968	NN	denotes	bleeding
T12835	21952-21959	IN	denotes	between
T12834	21947-21951	NN	denotes	time
T12833	21943-21946	DT	denotes	the
T12832	21940-21942	IN	denotes	as
T12831	21929-21939	VBN	denotes	determined
T12830	21927-21929	,	denotes	,
T12829	21926-21927	-RRB-	denotes	)
T12828	21917-21923	NN	denotes	Figure
T12827	21924-21926	NN	denotes	4B
T12826	21916-21917	-LRB-	denotes	(
T12825	22031-22040	VBN	denotes	increased
T12824	21900-21910	NN	denotes	rebleeding
T12823	21911-21915	NN	denotes	time
T12822	21896-21899	DT	denotes	The
T12821	21895-22269	sentence	denotes	The rebleeding time (Figure 4B), determined as the time between bleeding cessation and initiation of the second bleeding, was markedly increased in the A/J mice compared to the B6 mice and two strains, B6-Chr11A/J (CSS-11) and B6-Chr17A/J (CSS-17), had significantly (P < 0.002) longer rebleeding times compared to the B6 mice that were similar to values from the A/J mice.
T12820	21894-21895	.	denotes	.
T12819	21893-21894	-RRB-	denotes	)
T12818	21890-21893	NN	denotes	sec
T12817	21886-21889	CD	denotes	121
T12816	21885-21886	-LRB-	denotes	(
T12815	21877-21879	NN	denotes	B6
T12814	21880-21884	NNS	denotes	mice
T12813	21873-21876	DT	denotes	the
T12812	21869-21872	IN	denotes	for
T12811	21863-21868	NN	denotes	value
T12810	21859-21862	DT	denotes	the
T11799	20604-20608	IN	denotes	than
T11798	20601-20602	HYPH	denotes	/
T11797	20600-20601	NN	denotes	A
T11796	20602-20603	NN	denotes	J
T11795	20596-20599	DT	denotes	the
T11794	20593-20595	IN	denotes	in
T11793	20585-20592	JJR	denotes	greater
T11792	20572-20580	NN	denotes	collagen
T11791	20569-20571	IN	denotes	of
T11790	20581-20584	VBD	denotes	was
T11789	20562-20568	NN	denotes	amount
T11788	20558-20561	DT	denotes	The
T11787	20557-20632	sentence	denotes	The amount of collagen was greater in the A/J than the B6 mice (P < 0.05).
T11786	20556-20557	.	denotes	.
T11785	20551-20556	NN	denotes	mouse
T11784	20550-20551	SYM	denotes	/
T11783	20545-20550	NNS	denotes	areas
T11782	20542-20543	SYM	denotes	–
T11781	20543-20544	CD	denotes	3
T11780	20541-20542	CD	denotes	2
T11779	20536-20540	IN	denotes	from
T11778	20527-20535	NNS	denotes	sections
T11777	20524-20525	SYM	denotes	–
T11776	20525-20526	CD	denotes	4
T11775	20523-20524	CD	denotes	3
T11774	20518-20522	IN	denotes	from
T11773	20516-20517	-RRB-	denotes	)
T11772	20507-20513	NN	denotes	Figure
T11771	20514-20516	NN	denotes	3C
T11770	20506-20507	-LRB-	denotes	(
T11739	20338-20347	NN	denotes	Trichrome
T11738	20329-20335	NNP	denotes	Masson
T11737	20324-20328	IN	denotes	with
T11736	20311-20315	VBD	denotes	were
T11735	20305-20310	NNS	denotes	tails
T11734	20301-20304	DT	denotes	the
T11733	20298-20300	IN	denotes	of
T11732	20316-20323	VBN	denotes	stained
T11731	20289-20297	NNS	denotes	Sections
T11730	20288-20459	sentence	denotes	Sections of the tails were stained with Masson's Trichrome (Figure 3B) that detects collagen, the major platelet adhesive substratum for initiation of thrombus formation.
T11729	20287-20288	.	denotes	.
T11728	20279-20287	NNS	denotes	sections
T11727	20269-20270	-RRB-	denotes	)
T11726	20260-20266	NN	denotes	Figure
T11725	20267-20269	NN	denotes	3A
T11724	20259-20260	-LRB-	denotes	(
T11723	20271-20278	VBN	denotes	stained
T11722	20252-20253	HYPH	denotes	/
T11721	20253-20258	NN	denotes	Eosin
T11720	20241-20252	NN	denotes	Hematoxylin
T11719	20238-20240	IN	denotes	in
T11718	20228-20237	NN	denotes	cartilage
T11717	20227-20228	HYPH	denotes	/
T11716	20223-20227	NN	denotes	bone
T11715	20216-20222	NN	denotes	center
T11714	20213-20215	CC	denotes	or
T11713	20211-20213	,	denotes	,
T11712	20205-20211	NNS	denotes	glands
T11711	20195-20204	JJ	denotes	sebaceous
T11710	20193-20195	,	denotes	,
T11709	20184-20193	NNS	denotes	follicles
T11708	20179-20183	NN	denotes	hair
T11707	20176-20178	IN	denotes	in
T11706	20162-20166	VBD	denotes	were
T11705	20167-20175	VBN	denotes	observed
T11704	20138-20149	JJ	denotes	qualitative
T11703	20130-20137	JJ	denotes	obvious
T11702	20150-20161	NNS	denotes	differences
T11701	20127-20129	DT	denotes	No
T11700	20126-20288	sentence	denotes	No obvious qualitative differences were observed in hair follicles, sebaceous glands, or center bone/cartilage in Hematoxylin/Eosin (Figure 3A) stained sections.
T11699	20125-20126	.	denotes	.
T11698	20124-20125	CD	denotes	3
T11697	20117-20123	NN	denotes	Figure
T11696	20114-20116	IN	denotes	in
T11695	20104-20107	VBP	denotes	are
T11694	20108-20113	VBN	denotes	shown
T11693	20095-20103	NNS	denotes	sections
T11692	20080-20094	JJ	denotes	representative
T11691	20076-20079	CC	denotes	and
T11690	20063-20065	POS	denotes	's
T11689	20066-20075	NN	denotes	Trichrome
T11688	20057-20063	NNP	denotes	Masson
T11687	20054-20056	CC	denotes	or
T11686	20047-20048	HYPH	denotes	/
T11685	20048-20053	NN	denotes	Eosin
T11684	20036-20047	NN	denotes	Hematoxylin
T11683	20031-20035	IN	denotes	with
T11682	20018-20022	VBD	denotes	were
T11681	20010-20011	HYPH	denotes	/
T11675	19998-20001	DT	denotes	the
T11674	19993-19997	IN	denotes	from
T11673	19988-19992	NN	denotes	tail
T11672	19984-19987	DT	denotes	the
T11671	19981-19983	IN	denotes	of
T11670	20023-20030	VBN	denotes	stained
T11669	19972-19980	NNS	denotes	Sections
T11668	19971-20126	sentence	denotes	Sections of the tail from the B6 and A/J mice were stained with Hematoxylin/Eosin or Masson's Trichrome and representative sections are shown in Figure 3.
T11667	19970-19971	.	denotes	.
T11666	19953-19963	NN	denotes	rebleeding
T11665	19949-19952	CC	denotes	and
T11664	19940-19948	NN	denotes	bleeding
T11663	19964-19970	NNS	denotes	values
T11662	19936-19939	DT	denotes	the
T11661	19933-19935	IN	denotes	in
T11660	19922-19932	NNS	denotes	variations
T11659	19918-19921	DT	denotes	the
T11658	19914-19917	IN	denotes	for
T11657	19900-19905	MD	denotes	might
T11656	19906-19913	VB	denotes	account
T11655	19895-19899	WDT	denotes	that
T11654	19883-19894	NNS	denotes	differences
T11653	19879-19882	IN	denotes	for
T11652	19865-19869	VBD	denotes	were
T11651	19860-19864	NNS	denotes	mice
T11650	19856-19859	DT	denotes	the
T11649	19853-19855	IN	denotes	of
T11648	19870-19878	VBN	denotes	examined
T11647	19847-19852	NNS	denotes	tails
T11646	19843-19846	DT	denotes	The
T11645	19842-19971	sentence	denotes	The tails of the mice were examined for differences that might account for the variations in the bleeding and rebleeding values.
T11644	19840-19841	HYPH	denotes	/
T11643	19841-19842	NN	denotes	J
T11642	19839-19840	NN	denotes	A
T11641	19835-19838	CC	denotes	and
T11640	19832-19834	NN	denotes	B6
T11639	19829-19831	IN	denotes	in
T11638	19818-19828	NN	denotes	morphology
T11637	19813-19817	NN	denotes	Tail
T12848	22044-22047	DT	denotes	the
T12847	22041-22043	IN	denotes	in
T12846	22022-22030	RB	denotes	markedly
T12845	22018-22021	VBD	denotes	was
T12844	22016-22018	,	denotes	,
T12843	22001-22007	JJ	denotes	second
T12842	22008-22016	NN	denotes	bleeding
T12841	21997-22000	DT	denotes	the
T12840	21994-21996	IN	denotes	of
T11769	20491-20494	VBD	denotes	was
T11768	20489-20490	-RRB-	denotes	)
T11767	20480-20484	NN	denotes	tail
T11766	20478-20479	NN	denotes	%
T11765	20485-20489	NN	denotes	area
T11764	20477-20478	-LRB-	denotes	(
T11763	20495-20505	VBN	denotes	quantified
T11762	20469-20476	NN	denotes	content
T11761	20460-20468	NN	denotes	Collagen
T11760	20459-20557	sentence	denotes	Collagen content (% tail area) was quantified (Figure 3C) from 3–4 sections from 2–3 areas/mouse.
T11759	20458-20459	.	denotes	.
T11758	20449-20458	NN	denotes	formation
T11757	20440-20448	NN	denotes	thrombus
T11756	20437-20439	IN	denotes	of
T11755	20426-20436	NN	denotes	initiation
T11754	20422-20425	IN	denotes	for
T11753	20402-20410	JJ	denotes	adhesive
T11752	20393-20401	NN	denotes	platelet
T11751	20387-20392	JJ	denotes	major
T11750	20411-20421	NN	denotes	substratum
T11749	20383-20386	DT	denotes	the
T11748	20381-20383	,	denotes	,
T11747	20373-20381	NN	denotes	collagen
T11746	20365-20372	VBZ	denotes	detects
T11745	20360-20364	WDT	denotes	that
T11744	20358-20359	-RRB-	denotes	)
T11743	20349-20355	NN	denotes	Figure
T11742	20356-20358	NN	denotes	3B
T11741	20348-20349	-LRB-	denotes	(
T11740	20335-20337	POS	denotes	's
T11190	19620-19624	IN	denotes	from
T11189	19613-19619	NN	denotes	plasma
T11188	19608-19612	IN	denotes	than
T11187	19601-19607	JJR	denotes	higher
T11186	19589-19590	HYPH	denotes	/
T11185	19590-19591	NN	denotes	J
T11184	19588-19589	NN	denotes	A
T11183	19592-19596	NNS	denotes	mice
T11182	19584-19587	DT	denotes	the
T11181	19579-19583	IN	denotes	from
T11180	19572-19578	NN	denotes	plasma
T11179	19569-19571	IN	denotes	in
T11178	19565-19568	NN	denotes	Plg
T11177	19562-19564	IN	denotes	of
T11176	19548-19561	NN	denotes	concentration
T11175	19544-19547	DT	denotes	the
T11174	19542-19544	,	denotes	,
T11173	19597-19600	VBD	denotes	was
T11172	19538-19542	RB	denotes	Thus
T11171	19537-19811	sentence	denotes	Thus, the concentration of Plg in plasma from the A/J mice was higher than plasma from the B6 mice as determined by two methods and no difference in migration after electrophoresis was observed, suggesting no marked changes in the structure of Plg in the two mouse strains.
T11170	19536-19537	.	denotes	.
T11169	19535-19536	-RRB-	denotes	)
T11168	19528-19532	NN	denotes	Fig.
T11167	19533-19535	NN	denotes	1B
T11166	19527-19528	-LRB-	denotes	(
T11165	19520-19526	NN	denotes	plasma
T11164	19517-19519	IN	denotes	of
T11163	19505-19509	JJ	denotes	same
T11162	19510-19516	NN	denotes	amount
T11161	19501-19504	DT	denotes	the
T11160	19496-19500	IN	denotes	from
T11159	19494-19495	-RRB-	denotes	)
T11158	19485-19494	NNS	denotes	occasions
T11157	19475-19480	RBS	denotes	least
T11156	19481-19484	CD	denotes	two
T11155	19472-19474	RB	denotes	at
T11154	19469-19471	IN	denotes	on
T11153	19457-19461	VBD	denotes	were
T11152	19441-19451	JJ	denotes	individual
T11151	19452-19456	NNS	denotes	mice
T11150	19437-19440	CD	denotes	six
T11149	19462-19468	VBN	denotes	tested
T11148	19436-19437	-LRB-	denotes	(
T11147	19431-19435	NNS	denotes	mice
T11146	19428-19430	NN	denotes	B6
T11145	19424-19427	DT	denotes	the
T11144	19419-19423	IN	denotes	than
T11143	19416-19417	HYPH	denotes	/
T11142	19415-19416	NN	denotes	A
T11141	19417-19418	NN	denotes	J
T11140	19411-19414	DT	denotes	the
T11139	19408-19410	IN	denotes	in
T11138	19401-19407	JJR	denotes	higher
T11137	19399-19400	NN	denotes	%
T11136	19397-19399	CD	denotes	56
T11135	19387-19392	NNS	denotes	bands
T11134	19383-19386	DT	denotes	the
T11133	19380-19382	IN	denotes	of
T11132	19393-19396	VBD	denotes	was
T11131	19372-19379	NN	denotes	density
T11130	19368-19371	DT	denotes	the
T11129	19364-19367	CC	denotes	and
T11128	19351-19354	VBD	denotes	was
T11127	19343-19344	HYPH	denotes	/
T11126	19344-19345	NN	denotes	J
T11125	19342-19343	NN	denotes	A
T11124	19338-19341	CC	denotes	and
T11123	19346-19350	NNS	denotes	mice
T11122	19335-19337	NN	denotes	B6
T11121	19330-19334	IN	denotes	from
T11120	19322-19329	NNS	denotes	volumes
T11119	19314-19321	VBG	denotes	varying
T11118	19311-19313	IN	denotes	of
T11117	19304-19310	NN	denotes	plasma
T11116	19301-19303	IN	denotes	of
T11115	19290-19300	NNS	denotes	conditions
T11114	19281-19289	NN	denotes	reducing
T11113	19275-19280	IN	denotes	under
T11112	19269-19270	HYPH	denotes	-
T11111	19270-19274	NN	denotes	PAGE
T11110	19266-19269	NN	denotes	SDS
T11109	19261-19265	IN	denotes	from
T11108	19248-19255	NNP	denotes	Western
T11107	19256-19260	NN	denotes	blot
T11106	19244-19247	DT	denotes	the
T11105	19241-19243	IN	denotes	of
T11104	19355-19363	VBN	denotes	compared
T11103	19233-19240	NN	denotes	density
T11102	19229-19232	DT	denotes	The
T11101	19228-19537	sentence	denotes	The density of the Western blot from SDS-PAGE under reducing conditions of plasma of varying volumes from B6 and A/J mice was compared and the density of the bands was 56% higher in the A/J than the B6 mice (six individual mice were tested on at least two occasions) from the same amount of plasma (Fig. 1B).
T11100	19227-19228	.	denotes	.
T11099	19226-19227	-RRB-	denotes	)
T11098	19217-19220	RB	denotes	not
T11097	19212-19216	NNS	denotes	data
T11096	19221-19226	VBN	denotes	shown
T11095	19211-19212	-LRB-	denotes	(
T11094	19198-19201	VBD	denotes	was
T11093	19187-19197	NNS	denotes	conditions
T11092	19181-19186	DT	denotes	these
T11091	19175-19180	IN	denotes	under
T11090	19171-19174	NN	denotes	Plg
T11089	19157-19170	VBN	denotes	immunostained
T11088	19153-19156	IN	denotes	for
T11087	19143-19152	NN	denotes	migration
T11086	19140-19142	IN	denotes	in
T11085	19202-19210	VBN	denotes	observed
T11084	19129-19139	NN	denotes	difference
T11083	19126-19128	DT	denotes	No
T11082	19125-19228	sentence	denotes	No difference in migration for immunostained Plg under these conditions was observed (data not shown).
T11081	19124-19125	.	denotes	.
T11080	19099-19113	VBG	denotes	non-denaturing
T11079	19095-19098	CC	denotes	and
T11078	19093-19095	,	denotes	,
T11077	19082-19093	JJ	denotes	non-reduced
T11076	19080-19082	,	denotes	,
T11075	19114-19124	NNS	denotes	conditions
T11074	19073-19080	VBN	denotes	reduced
T11073	19067-19072	IN	denotes	under
T11072	19051-19066	NN	denotes	electrophoresis
T11071	19048-19050	IN	denotes	to
T11070	19033-19037	VBD	denotes	were
T11069	19028-19032	NNS	denotes	mice
T11068	19025-19026	HYPH	denotes	/
T11067	19024-19025	NN	denotes	A
T11066	19026-19027	NN	denotes	J
T11065	19020-19023	DT	denotes	the
T11064	19016-19019	CC	denotes	and
T11063	19013-19015	NN	denotes	B6
T11062	19009-19012	DT	denotes	the
T11061	19004-19008	IN	denotes	from
T11060	18997-19003	NN	denotes	plasma
T11059	18995-18997	,	denotes	,
T11058	18988-18989	HYPH	denotes	/
T11057	18989-18990	NN	denotes	J
T11056	18987-18988	NN	denotes	A
T11055	18991-18995	NNS	denotes	mice
T11054	18983-18986	DT	denotes	the
T11053	18978-18982	IN	denotes	from
T11052	18974-18977	NN	denotes	Plg
T11051	18971-18973	IN	denotes	of
T11050	18963-18970	NNS	denotes	changes
T11049	18953-18962	NN	denotes	structure
T11048	18945-18952	NN	denotes	protein
T11047	18934-18939	EX	denotes	there
T11046	18940-18944	VBD	denotes	were
T11045	18926-18933	IN	denotes	whether
T11044	19038-19047	VBN	denotes	subjected
T11043	18916-18925	VB	denotes	determine
T11042	18913-18915	TO	denotes	To
T11041	18912-19125	sentence	denotes	To determine whether there were protein structure changes of Plg from the A/J mice, plasma from the B6 and the A/J mice were subjected to electrophoresis under reduced, non-reduced, and non-denaturing conditions.
T11040	18911-18912	.	denotes	.
T11039	18904-18905	HYPH	denotes	/
T11038	18905-18906	NN	denotes	J
T11037	18903-18904	NN	denotes	A
T11036	18907-18911	NNS	denotes	mice
T11035	18899-18902	DT	denotes	the
T11034	18896-18898	IN	denotes	in
T11033	18889-18895	JJR	denotes	higher
T11032	18884-18888	RB	denotes	also
T11031	18870-18880	NN	denotes	fibrinogen
T11030	18881-18883	VBZ	denotes	is
T11029	18864-18869	IN	denotes	since
T11028	18862-18864	,	denotes	,
T11027	18857-18862	JJ	denotes	clear
T11026	18853-18856	RB	denotes	not
T11025	18837-18848	NNS	denotes	differences
T11024	18831-18836	DT	denotes	these
T11023	18828-18830	IN	denotes	of
T11022	18849-18852	VBP	denotes	are
T11021	18804-18814	JJ	denotes	functional
T11020	18815-18827	NNS	denotes	consequences
T11019	18800-18803	DT	denotes	The
T11018	18799-18912	sentence	denotes	The functional consequences of these differences are not clear, since fibrinogen is also higher in the A/J mice.
T11017	18798-18799	.	denotes	.
T11016	18797-18798	-RRB-	denotes	)
T11015	18796-18797	CD	denotes	2
T11014	18790-18795	NN	denotes	Table
T11013	18789-18790	-LRB-	denotes	(
T11012	18781-18783	NN	denotes	B6
T11011	18784-18788	NNS	denotes	mice
T11010	18777-18780	DT	denotes	the
T11009	18774-18776	IN	denotes	to
T11008	18765-18773	VBN	denotes	compared
T11007	18760-18764	WRB	denotes	when
T11006	18752-18753	SYM	denotes	/
T11223	19810-19811	.	denotes	.
T11222	19797-19802	NN	denotes	mouse
T11005	18753-18754	NN	denotes	J
T11004	18751-18752	NN	denotes	A
T11003	18755-18759	NNS	denotes	mice
T11002	18747-18750	DT	denotes	the
T11001	18744-18746	IN	denotes	in
T11000	18729-18733	RB	denotes	also
T10999	18724-18728	VBD	denotes	were
T10998	18711-18712	HYPH	denotes	-
T10997	18712-18723	NN	denotes	anitplasmin
T10996	18709-18711	NN	denotes	α2
T10995	18705-18708	CC	denotes	and
T10994	18703-18705	,	denotes	,
T10993	18693-18694	CD	denotes	1
T10992	18692-18693	HYPH	denotes	-
T10991	18695-18703	NN	denotes	activity
T10990	18689-18692	NN	denotes	PAI
T10989	18687-18689	,	denotes	,
T10988	18679-18687	NN	denotes	activity
T10987	18666-18678	JJ	denotes	fibrinolytic
T10986	18664-18666	,	denotes	,
T10985	18656-18664	NN	denotes	addition
T10984	18734-18743	VBN	denotes	increased
T10983	18653-18655	IN	denotes	In
T10982	18652-18799	sentence	denotes	In addition, fibrinolytic activity, PAI-1 activity, and α2-anitplasmin were also increased in the A/J mice when compared to the B6 mice (Table 2).
T10981	18651-18652	.	denotes	.
T10980	18647-18651	NNS	denotes	mice
T10979	18644-18646	NN	denotes	B6
T10978	18641-18643	IN	denotes	in
T10977	18636-18640	IN	denotes	than
T10976	18628-18629	HYPH	denotes	/
T10975	18629-18630	NN	denotes	J
T10974	18627-18628	NN	denotes	A
T10973	18631-18635	NNS	denotes	mice
T10972	18623-18626	DT	denotes	the
T10971	18620-18622	IN	denotes	in
T10970	18613-18619	JJR	denotes	higher
T10969	18611-18612	NN	denotes	%
T10968	18609-18611	CD	denotes	34
T10967	18605-18608	VBD	denotes	was
T10966	18591-18604	NN	denotes	concentration
T10965	18587-18590	NN	denotes	Plg
T10964	18586-18652	sentence	denotes	Plg concentration was 34% higher in the A/J mice than in B6 mice.
T10963	18582-18586	NNS	denotes	mice
T10962	18579-18581	NN	denotes	B6
T10961	18574-18578	IN	denotes	than
T10960	18571-18572	HYPH	denotes	/
T10959	18572-18573	NN	denotes	J
T10958	18570-18571	NN	denotes	A
T10957	18567-18569	IN	denotes	in
T10956	18558-18559	CD	denotes	1
T10955	18557-18558	HYPH	denotes	-
T10954	18554-18557	NN	denotes	PAI
T10953	18550-18553	CC	denotes	and
T10952	18560-18566	JJR	denotes	higher
T10951	18546-18549	NN	denotes	Plg
T10315	17764-17770	JJ	denotes	common
T10314	17771-17778	NN	denotes	pathway
T10313	17760-17763	DT	denotes	the
T10312	17750-17759	VBZ	denotes	initiates
T10311	17744-17749	WDT	denotes	which
T10310	17742-17744	,	denotes	,
T10309	17741-17742	CD	denotes	X
T10308	17734-17740	NN	denotes	Factor
T10307	17716-17724	NNS	denotes	pathways
T10306	17711-17715	DT	denotes	both
T10305	17708-17710	IN	denotes	of
T10304	17725-17733	VBP	denotes	activate
T10303	17699-17707	NNS	denotes	products
T10302	17695-17698	DT	denotes	The
T10301	17694-17836	sentence	denotes	The products of both pathways activate Factor X, which initiates the common pathway leading to thrombin generation and fibrin clot formation.
T10300	17693-17694	.	denotes	.
T10299	17692-17693	-RRB-	denotes	)
T10298	17688-17692	CD	denotes	VIII
T10297	17684-17687	CC	denotes	and
T10296	17681-17683	CD	denotes	IX
T10295	17679-17681	,	denotes	,
T10294	17677-17679	CD	denotes	XI
T10293	17675-17677	,	denotes	,
T10292	17672-17675	CD	denotes	XII
T10291	17664-17671	NNS	denotes	Factors
T10290	17661-17663	IN	denotes	of
T10289	17650-17660	NN	denotes	activation
T10288	17649-17650	-LRB-	denotes	(
T10287	17631-17640	JJ	denotes	intrinsic
T10286	17641-17648	NN	denotes	pathway
T10285	17627-17630	DT	denotes	the
T10284	17624-17626	IN	denotes	of
T10283	17612-17623	NN	denotes	measurement
T10282	17610-17611	DT	denotes	a
T10281	17602-17606	NN	denotes	aPTT
T10280	17607-17609	VBZ	denotes	is
T10279	17596-17601	IN	denotes	while
T10278	17594-17595	-RRB-	denotes	)
T10277	17588-17594	NN	denotes	factor
T10276	17581-17587	NN	denotes	tissue
T10275	17578-17580	IN	denotes	by
T10274	17574-17577	CD	denotes	VII
T10273	17567-17573	NN	denotes	Factor
T10272	17564-17566	IN	denotes	of
T10271	17553-17563	NN	denotes	activation
T10270	17552-17553	-LRB-	denotes	(
T10269	17532-17543	NN	denotes	coagulation
T10268	17522-17531	JJ	denotes	extrinsic
T10267	17544-17551	NN	denotes	pathway
T10266	17518-17521	DT	denotes	the
T10265	17515-17517	IN	denotes	of
T10264	17503-17514	NN	denotes	measurement
T10263	17501-17502	DT	denotes	a
T10262	17498-17500	VBZ	denotes	is
T10261	17495-17497	NN	denotes	PT
T10260	17494-17694	sentence	denotes	PT is a measurement of the extrinsic coagulation pathway (activation of Factor VII by tissue factor) while aPTT is a measurement of the intrinsic pathway (activation of Factors XII, XI, IX and VIII).
T10259	17493-17494	.	denotes	.
T10258	17480-17484	VBD	denotes	were
T10257	17478-17479	-RRB-	denotes	)
T10256	17474-17478	NN	denotes	aPTT
T10255	17473-17474	-LRB-	denotes	(
T10254	17453-17467	NN	denotes	thromboplastin
T10253	17445-17452	JJ	denotes	partial
T10252	17468-17472	NN	denotes	time
T10251	17435-17444	VBN	denotes	activated
T10250	17431-17434	CC	denotes	and
T10249	17429-17430	-RRB-	denotes	)
T10248	17427-17429	NN	denotes	PT
T10247	17426-17427	-LRB-	denotes	(
T10246	17421-17425	NN	denotes	time
T10245	17409-17420	NN	denotes	prothrombin
T10244	17407-17409	,	denotes	,
T10243	17389-17399	NN	denotes	rebleeding
T10242	17385-17388	CC	denotes	and
T10241	17376-17384	NN	denotes	bleeding
T10240	17400-17407	NNS	denotes	results
T10239	17372-17375	DT	denotes	the
T10238	17369-17371	IN	denotes	to
T10237	17361-17368	NNS	denotes	factors
T10370	18050-18051	.	denotes	.
T10369	18036-18042	JJ	denotes	inbred
T10368	18032-18035	CD	denotes	two
T10367	18043-18050	NNS	denotes	strains
T10366	18028-18031	DT	denotes	the
T10365	18025-18027	IN	denotes	in
T10364	18015-18024	JJ	denotes	different
T10363	18011-18014	RB	denotes	not
T10362	17988-17999	NN	denotes	coagulation
T10361	18000-18007	NN	denotes	pathway
T10360	17984-17987	DT	denotes	the
T10359	18008-18010	VBZ	denotes	is
T10358	17979-17983	IN	denotes	that
T10357	17971-17978	VBP	denotes	suggest
T10356	17963-17970	NNS	denotes	results
T10355	17957-17962	DT	denotes	These
T10354	17956-18051	sentence	denotes	These results suggest that the coagulation pathway is not different in the two inbred strains.
T10353	17955-17956	.	denotes	.
T10352	17954-17955	-RRB-	denotes	)
T10351	17953-17954	CD	denotes	2
T10350	17947-17952	NN	denotes	Table
T10349	17946-17947	-LRB-	denotes	(
T10348	17932-17937	NN	denotes	mouse
T10347	17928-17931	CD	denotes	two
T10346	17938-17945	NNS	denotes	strains
T10345	17924-17927	DT	denotes	the
T10344	17916-17923	IN	denotes	between
T10343	17906-17915	JJ	denotes	different
T10342	17902-17905	RB	denotes	not
T10341	17897-17901	VBD	denotes	were
T10340	17890-17896	NNS	denotes	values
T10339	17886-17889	CC	denotes	and
T10338	17878-17879	HYPH	denotes	/
T10337	17879-17880	NN	denotes	J
T10336	17877-17878	NN	denotes	A
T10335	17873-17876	CC	denotes	and
T10334	17870-17872	NN	denotes	B6
T10333	17881-17885	NNS	denotes	mice
T10332	17866-17869	DT	denotes	the
T10331	17863-17865	IN	denotes	in
T10330	17849-17853	VBD	denotes	were
T10329	17844-17848	NN	denotes	aPTT
T10328	17840-17843	CC	denotes	and
T10327	17854-17862	VBN	denotes	measured
T10326	17837-17839	NN	denotes	PT
T10325	17836-17956	sentence	denotes	PT and aPTT were measured in the B6 and A/J mice and values were not different between the two mouse strains (Table 2).
T10324	17835-17836	.	denotes	.
T10323	17826-17835	NN	denotes	formation
T10322	17821-17825	NN	denotes	clot
T10321	17814-17820	NN	denotes	fibrin
T10320	17810-17813	CC	denotes	and
T10319	17799-17809	NN	denotes	generation
T10318	17790-17798	NN	denotes	thrombin
T10317	17787-17789	IN	denotes	to
T10316	17779-17786	VBG	denotes	leading
T9877	17227-17230	NN	denotes	Plg
T9876	17231-17238	NN	denotes	network
T9875	17223-17226	DT	denotes	the
T9874	17220-17222	IN	denotes	of
T9873	17209-17219	NN	denotes	regulation
T9872	17205-17208	DT	denotes	the
T9871	17202-17204	IN	denotes	in
T9870	17190-17201	NNS	denotes	differences
T9869	17178-17181	MD	denotes	may
T9868	17175-17176	HYPH	denotes	/
T9867	17174-17175	NN	denotes	A
T9866	17176-17177	NN	denotes	J
T9865	17170-17173	DT	denotes	the
T9864	17167-17169	IN	denotes	in
T9863	17182-17189	VB	denotes	suggest
T9842	17037-17046	JJ	denotes	prolonged
T9841	17058-17062	NN	denotes	time
T9840	17035-17036	DT	denotes	a
T9839	17032-17034	IN	denotes	in
T9838	17098-17106	VBD	denotes	resulted
T9837	17021-17024	RB	denotes	not
T9836	17017-17020	VBD	denotes	did
T9835	17002-17005	NN	denotes	Plg
T9834	17006-17016	NN	denotes	deficiency
T9833	17000-17001	DT	denotes	a
T9832	17025-17031	VB	denotes	result
T9831	16991-16999	IN	denotes	Although
T9830	16990-17127	sentence	denotes	Although a Plg deficiency did not result in a prolonged rebleeding time as anticipated, a PAI-1 deficiency resulted in a shortened time.
T9829	16989-16990	.	denotes	.
T9828	16982-16984	NN	denotes	B6
T9827	16985-16989	NNS	denotes	mice
T9826	16978-16981	DT	denotes	the
T9825	16974-16977	IN	denotes	for
T9824	16969-16973	IN	denotes	than
T9823	16963-16968	JJR	denotes	lower
T9822	16954-16962	RB	denotes	1.8-fold
T9821	16950-16953	VBD	denotes	was
T9820	16944-16949	WDT	denotes	which
T9819	16942-16944	,	denotes	,
T9818	16927-16937	NN	denotes	rebleeding
T9817	16917-16918	-RRB-	denotes	)
T9816	16911-16912	SYM	denotes	<
T9815	16909-16910	NN	denotes	P
T9814	16913-16917	CD	denotes	0.05
T9813	16908-16909	-LRB-	denotes	(
T9812	16919-16926	VBN	denotes	reduced
T9811	16894-16907	RB	denotes	significantly
T9810	16938-16942	NN	denotes	time
T9809	16892-16893	DT	denotes	a
T9808	16888-16891	VBD	denotes	had
T9807	16881-16882	SYM	denotes	-
T9806	16880-16881	HYPH	denotes	/
T9805	16879-16880	SYM	denotes	-
T9804	16878-16879	CD	denotes	1
T9803	16877-16878	HYPH	denotes	-
T9802	16883-16887	NNS	denotes	mice
T9801	16874-16877	NN	denotes	PAI
T9800	16870-16873	CC	denotes	but
T9799	16868-16870	,	denotes	,
T9798	16857-16868	NNS	denotes	littermates
T9797	16854-16856	NN	denotes	WT
T9796	16851-16853	IN	denotes	to
T9795	16842-16850	VBN	denotes	compared
T9794	16835-16836	SYM	denotes	-
T9793	16834-16835	HYPH	denotes	/
T9792	16833-16834	SYM	denotes	-
T9791	16837-16841	NNS	denotes	mice
T9790	16830-16833	NN	denotes	Plg
T9789	16827-16829	IN	denotes	in
T9788	16817-16826	JJ	denotes	different
T9787	16813-16816	RB	denotes	not
T9786	16809-16812	VBD	denotes	was
T9785	16804-16808	NN	denotes	time
T9784	16793-16803	VBG	denotes	Rebleeding
T9783	16792-16990	sentence	denotes	Rebleeding time was not different in Plg-/- mice compared to WT littermates, but PAI-1-/- mice had a significantly (P < 0.05) reduced rebleeding time, which was 1.8-fold lower than for the B6 mice.
T9782	16791-16792	.	denotes	.
T9781	16790-16791	-RRB-	denotes	)
T9780	16781-16787	NN	denotes	Figure
T9779	16788-16790	NN	denotes	2B
T9778	16780-16781	-LRB-	denotes	(
T9777	16768-16772	RB	denotes	also
T9776	16763-16767	VBD	denotes	were
T9775	16756-16757	SYM	denotes	-
T9774	16755-16756	HYPH	denotes	/
T9773	16754-16755	SYM	denotes	-
T9772	16753-16754	CD	denotes	1
T9771	16752-16753	HYPH	denotes	-
T9770	16749-16752	NN	denotes	PAI
T9769	16745-16748	CC	denotes	and
T9768	16743-16744	SYM	denotes	-
T9767	16742-16743	HYPH	denotes	/
T9766	16741-16742	SYM	denotes	-
T9765	16758-16762	NNS	denotes	mice
T9764	16738-16741	NN	denotes	Plg
T9763	16736-16738	,	denotes	,
T9762	16732-16736	NN	denotes	time
T9761	16721-16731	NN	denotes	rebleeding
T9760	16710-16713	MD	denotes	may
T9759	16690-16702	JJ	denotes	fibrinolytic
T9758	16703-16709	NN	denotes	system
T9757	16686-16689	DT	denotes	the
T9756	16683-16685	IN	denotes	in
T9755	16671-16682	NNS	denotes	alterations
T9754	16714-16720	VB	denotes	affect
T9753	16667-16670	WRB	denotes	how
T9752	16773-16779	VBN	denotes	tested
T9751	16657-16666	VB	denotes	determine
T9750	16654-16656	TO	denotes	To
T9749	16653-16792	sentence	denotes	To determine how alterations in the fibrinolytic system may affect rebleeding time, Plg-/- and PAI-1-/- mice were also tested (Figure 2B).
T9748	16652-16653	.	denotes	.
T9747	16645-16647	NN	denotes	B6
T9746	16648-16652	NNS	denotes	mice
T9745	16641-16644	DT	denotes	the
T9744	16636-16640	IN	denotes	than
T9743	16625-16630	NN	denotes	Lepob
T9742	16631-16635	NNS	denotes	mice
T9741	16621-16624	DT	denotes	the
T9740	16618-16620	IN	denotes	in
T9739	16613-16617	JJR	denotes	less
T9738	16604-16612	RB	denotes	8.5-fold
T9737	16597-16603	RB	denotes	nearly
T9736	16577-16587	NN	denotes	rebleeding
T9735	16588-16592	NN	denotes	time
T9734	16573-16576	DT	denotes	the
T9733	16571-16573	,	denotes	,
T9732	16563-16571	NN	denotes	contrast
T9731	16593-16596	VBD	denotes	was
T9730	16560-16562	IN	denotes	In
T9729	16559-16653	sentence	denotes	In contrast, the rebleeding time was nearly 8.5-fold less in the Lepob mice than the B6 mice.
T9728	16558-16559	.	denotes	.
T9727	16551-16553	NN	denotes	B6
T9726	16554-16558	NNS	denotes	mice
T9725	16547-16550	DT	denotes	the
T9724	16542-16546	IN	denotes	than
T9723	16535-16536	-RRB-	denotes	)
T9722	16528-16529	SYM	denotes	<
T9721	16530-16535	CD	denotes	0.001
T9720	16526-16527	NN	denotes	P
T9719	16524-16526	,	denotes	,
T9718	16516-16524	RB	denotes	2.6-fold
T9717	16515-16516	-LRB-	denotes	(
T9716	16537-16541	NNS	denotes	mice
T9715	16512-16513	HYPH	denotes	/
T9714	16513-16514	NN	denotes	J
T9713	16511-16512	NN	denotes	A
T9712	16508-16510	IN	denotes	in
T9711	16501-16507	JJR	denotes	higher
T9710	16487-16500	RB	denotes	significantly
T9709	16482-16486	VBD	denotes	were
T9708	16476-16481	NNS	denotes	times
T9707	16465-16475	NN	denotes	Rebleeding
T9706	16464-16559	sentence	denotes	Rebleeding times were significantly higher in A/J (2.6-fold, P < 0.001) mice than the B6 mice.
T9705	16463-16464	.	denotes	.
T9704	16462-16463	-RRB-	denotes	)
T9703	16453-16459	NN	denotes	Figure
T9702	16460-16462	NN	denotes	2B
T9701	16452-16453	-LRB-	denotes	(
T9700	16436-16442	JJ	denotes	second
T9699	16443-16451	NN	denotes	bleeding
T9698	16432-16435	DT	denotes	the
T9697	16429-16431	IN	denotes	of
T9696	16423-16428	NN	denotes	start
T9695	16419-16422	DT	denotes	the
T9694	16415-16418	CC	denotes	and
T9693	16406-16414	NN	denotes	bleeding
T9692	16403-16405	IN	denotes	of
T9673	15754-15755	.	denotes	.
T9672	15743-15746	CD	denotes	two
T9671	15747-15754	NNS	denotes	strains
T9670	15737-15742	DT	denotes	these
T9669	15734-15736	IN	denotes	in
T9668	15722-15725	RB	denotes	not
T9667	15719-15721	VBZ	denotes	is
T9666	15726-15733	VBN	denotes	altered
T9665	15707-15718	NN	denotes	aggregation
T9664	15698-15706	NN	denotes	platelet
T9663	15688-15697	VBD	denotes	suggested
T9662	15684-15687	CC	denotes	and
T9661	15676-15677	HYPH	denotes	/
T9660	15677-15678	NN	denotes	J
T9659	15675-15676	NN	denotes	A
T9658	15671-15674	CC	denotes	and
T9657	15679-15683	NNS	denotes	mice
T9656	15668-15670	NN	denotes	B6
T9655	15660-15667	IN	denotes	between
T9654	15646-15654	NN	denotes	bleeding
T9653	15655-15659	NN	denotes	time
T9652	15642-15645	DT	denotes	the
T9651	15639-15641	IN	denotes	in
T9650	15628-15638	NN	denotes	difference
T9649	15625-15627	DT	denotes	no
T9648	15615-15620	EX	denotes	there
T9647	15613-15615	,	denotes	,
T9646	15609-15613	NN	denotes	time
T9645	15600-15608	NN	denotes	bleeding
T9644	15597-15599	IN	denotes	in
T9643	15588-15596	NN	denotes	increase
T9642	15580-15587	RB	denotes	10-fold
T9641	15576-15579	CC	denotes	and
T9640	15560-15568	NN	denotes	platelet
T9639	15569-15575	NN	denotes	defect
T9638	15558-15559	DT	denotes	a
T9637	15553-15557	IN	denotes	with
T9636	15542-15547	NN	denotes	Lepob
T9635	15548-15552	NNS	denotes	mice
T9634	15538-15541	DT	denotes	the
T9633	15535-15537	IN	denotes	to
T9632	15526-15534	NN	denotes	contrast
T9631	15621-15624	VBD	denotes	was
T9630	15523-15525	IN	denotes	In
T9629	15522-15755	sentence	denotes	In contrast to the Lepob mice with a platelet defect and 10-fold increase in bleeding time, there was no difference in the bleeding time between B6 and A/J mice and suggested platelet aggregation is not altered in these two strains.
T9628	15521-15522	.	denotes	.
T9627	15517-15521	NNS	denotes	mice
T9862	17151-17161	NN	denotes	rebleeding
T9861	17141-17150	VBN	denotes	increased
T9860	17132-17140	RB	denotes	markedly
T9859	17162-17166	NN	denotes	time
T9858	17128-17131	DT	denotes	The
T9857	17127-17239	sentence	denotes	The markedly increased rebleeding time in the A/J may suggest differences in the regulation of the Plg network.
T9856	17126-17127	.	denotes	.
T9855	17112-17121	VBN	denotes	shortened
T9854	17122-17126	NN	denotes	time
T9853	17110-17111	DT	denotes	a
T9852	17107-17109	IN	denotes	in
T9851	17085-17086	CD	denotes	1
T9850	17084-17085	HYPH	denotes	-
T9849	17081-17084	NN	denotes	PAI
T9848	17087-17097	NN	denotes	deficiency
T9847	17079-17080	DT	denotes	a
T9846	17077-17079	,	denotes	,
T9845	17066-17077	VBN	denotes	anticipated
T9844	17063-17065	IN	denotes	as
T9843	17047-17057	NN	denotes	rebleeding
T9626	15514-15516	NN	denotes	B6
T9597	15401-15403	IN	denotes	in
T9596	15399-15400	NN	denotes	%
T9595	15397-15399	CD	denotes	66
T9594	15394-15396	IN	denotes	by
T9593	15382-15383	-RRB-	denotes	)
T9592	15374-15375	SYM	denotes	=
T9591	15372-15373	NN	denotes	P
T9590	15376-15382	CD	denotes	0.0001
T9589	15371-15372	-LRB-	denotes	(
T9588	15357-15370	RB	denotes	significantly
T9587	15352-15356	RB	denotes	also
T9586	15348-15351	VBD	denotes	was
T9585	15384-15393	VBN	denotes	increased
T9584	15343-15347	NN	denotes	time
T9583	15334-15342	NN	denotes	Bleeding
T9582	15333-15452	sentence	denotes	Bleeding time was also significantly (P = 0.0001) increased by 66% in the Plg-/- mice compared to WT mice littermates.
T9581	15332-15333	.	denotes	.
T9580	15328-15332	NNS	denotes	mice
T9579	15325-15327	NN	denotes	B6
T9578	15322-15324	IN	denotes	to
T9577	15313-15321	VBN	denotes	compared
T9576	15308-15312	NN	denotes	time
T9575	15299-15307	NN	denotes	bleeding
T9574	15296-15298	IN	denotes	in
T9573	15279-15286	RB	denotes	10-fold
T9572	15277-15278	DT	denotes	a
T9571	15287-15295	NN	denotes	increase
T9570	15270-15276	RB	denotes	nearly
T9569	15260-15265	EX	denotes	there
T9568	15258-15259	-RRB-	denotes	)
T9567	15249-15255	NN	denotes	Figure
T9566	15256-15258	NN	denotes	2A
T9565	15248-15249	-LRB-	denotes	(
T9564	15237-15242	NN	denotes	Lepob
T9563	15243-15247	NNS	denotes	mice
T9562	15233-15236	DT	denotes	the
T9561	15266-15269	VBD	denotes	was
T9560	15230-15232	IN	denotes	In
T9559	15229-15333	sentence	denotes	In the Lepob mice (Figure 2A) there was nearly a 10-fold increase in bleeding time compared to B6 mice.
T9558	15228-15229	.	denotes	.
T9557	15220-15228	NN	denotes	function
T9556	15211-15219	NN	denotes	platelet
T9555	15207-15210	IN	denotes	for
T9554	15197-15206	NN	denotes	reference
T9553	15195-15196	DT	denotes	a
T9552	15192-15194	IN	denotes	as
T9551	15182-15191	VBN	denotes	evaluated
T9550	15177-15181	VBD	denotes	were
T9549	15173-15176	CC	denotes	and
T9548	15171-15172	-RRB-	denotes	]
T9547	15169-15171	CD	denotes	26
T9546	15168-15169	-LRB-	denotes	[
T9545	15147-15155	NN	denotes	platelet
T9544	15156-15167	NN	denotes	aggregation
T9543	15138-15146	VBN	denotes	impaired
T9542	15133-15137	VBP	denotes	have
T9541	15122-15127	NN	denotes	Lepob
T9540	15128-15132	NNS	denotes	mice
T9539	15118-15121	DT	denotes	The
T9538	15117-15229	sentence	denotes	The Lepob mice have impaired platelet aggregation [26] and were evaluated as a reference for platelet function.
T9537	15116-15117	.	denotes	.
T9536	15105-15109	RB	denotes	also
T9535	15100-15104	VBD	denotes	were
T9534	15098-15100	,	denotes	,
T9533	15092-15093	SYM	denotes	-
T9532	15091-15092	HYPH	denotes	/
T9531	15090-15091	SYM	denotes	-
T9530	15087-15090	NN	denotes	PAI
T9529	15083-15086	CC	denotes	and
T9528	15081-15082	SYM	denotes	-
T9527	15080-15081	HYPH	denotes	/
T9526	15079-15080	SYM	denotes	-
T9525	15094-15098	NNS	denotes	mice
T9524	15076-15079	NN	denotes	Plg
T9523	15074-15076	,	denotes	,
T9522	15064-15074	NN	denotes	thrombosis
T9521	15061-15063	CC	denotes	or
T9520	15059-15061	,	denotes	,
T9519	15055-15059	NNS	denotes	mice
T9518	15049-15054	NN	denotes	Lepob
T9517	15047-15049	,	denotes	,
T9516	15037-15047	NN	denotes	hemostasis
T9515	15034-15036	IN	denotes	in
T9514	15022-15033	NNS	denotes	alterations
T9513	15016-15021	JJ	denotes	known
T9512	15011-15015	IN	denotes	with
T9511	15006-15010	NNS	denotes	mice
T9510	15004-15006	,	denotes	,
T9509	14994-14995	HYPH	denotes	/
T9508	14995-14996	NN	denotes	J
T9449	14715-14723	NN	denotes	bleeding
T9448	14711-14714	DT	denotes	the
T9447	14727-14731	VB	denotes	stop
T9446	14707-14710	IN	denotes	for
T9445	14702-14706	NN	denotes	time
T9444	14698-14701	DT	denotes	the
T9443	14688-14697	VBG	denotes	measuring
T9442	14684-14687	CC	denotes	and
T9441	14677-14683	NN	denotes	saline
T9440	14672-14676	JJ	denotes	warm
T9439	14669-14671	IN	denotes	in
T9438	14664-14668	NN	denotes	tail
T9437	14660-14663	DT	denotes	the
T9436	14652-14659	VBG	denotes	placing
T9435	14650-14652	,	denotes	,
T9434	14640-14642	NN	denotes	mm
T9433	14638-14639	CD	denotes	5
T9432	14643-14650	NN	denotes	segment
T9431	14636-14637	DT	denotes	a
T9430	14627-14635	VBG	denotes	clipping
T9429	14625-14627	,	denotes	,
T9428	14621-14625	NN	denotes	tail
T9427	14617-14620	DT	denotes	the
T9426	14606-14616	VBG	denotes	prewarming
T9425	14600-14605	IN	denotes	after
T9424	14585-14588	VBD	denotes	was
T9423	14583-14585	,	denotes	,
T9422	14575-14583	NN	denotes	activity
T9421	14564-14574	JJ	denotes	hemostatic
T9420	14561-14563	IN	denotes	of
T9419	14551-14560	NN	denotes	indicator
T9418	14548-14550	DT	denotes	an
T9417	14546-14548	,	denotes	,
T9416	14589-14599	VBN	denotes	determined
T9415	14533-14541	NN	denotes	bleeding
T9414	14542-14546	NN	denotes	time
T9413	14529-14532	DT	denotes	The
T9412	14528-14732	sentence	denotes	The bleeding time, an indicator of hemostatic activity, was determined after prewarming the tail, clipping a 5 mm segment, placing the tail in warm saline and measuring the time for the bleeding to stop.
T9411	14521-14522	HYPH	denotes	/
T9410	14522-14523	NN	denotes	J
T9409	14520-14521	NN	denotes	A
T9408	14516-14519	CC	denotes	and
T9407	14524-14528	NNS	denotes	mice
T9406	14513-14515	NN	denotes	B6
T9405	14510-14512	IN	denotes	in
T9404	14505-14509	NN	denotes	time
T9403	14494-14504	NN	denotes	rebleeding
T9402	14491-14493	IN	denotes	in
T9401	14479-14490	NNS	denotes	differences
T9400	14472-14478	JJ	denotes	Marked
T9479	14883-14884	NN	denotes	J
T9478	14881-14882	NN	denotes	A
T9477	14878-14880	IN	denotes	in
T9476	14868-14877	JJ	denotes	different
T9475	14864-14867	RB	denotes	not
T9474	14860-14863	VBD	denotes	was
T9473	14855-14859	NN	denotes	time
T9472	14846-14854	NN	denotes	Bleeding
T9471	14845-14922	sentence	denotes	Bleeding time was not different in A/J mice compared to B6 mice (Figure 2A).
T9470	14844-14845	.	denotes	.
T9469	14835-14844	JJ	denotes	dependent
T9468	14828-14834	NN	denotes	gender
T9467	14824-14827	RB	denotes	not
T9466	14820-14823	VBD	denotes	was
T9465	14816-14819	CC	denotes	and
T9464	14802-14807	NN	denotes	mouse
T9463	14808-14815	NNS	denotes	strains
T9462	14792-14801	JJ	denotes	different
T9461	14789-14791	IN	denotes	in
T9460	14776-14788	JJ	denotes	reproducible
T9459	14772-14775	CC	denotes	and
T9458	14761-14771	JJ	denotes	consistent
T9457	14757-14760	VBD	denotes	was
T9456	14747-14756	NN	denotes	procedure
T9455	14742-14746	DT	denotes	this
T9454	14736-14741	VBD	denotes	found
T9453	14733-14735	PRP	denotes	We
T9452	14732-14845	sentence	denotes	We found this procedure was consistent and reproducible in different mouse strains and was not gender dependent.
T9451	14731-14732	.	denotes	.
T9450	14724-14726	TO	denotes	to
T8374	13894-13896	IN	denotes	to
T8373	13885-13893	NN	denotes	thrombus
T8372	13881-13884	DT	denotes	the
T8371	13878-13880	IN	denotes	of
T8370	13872-13877	NN	denotes	ratio
T8369	13868-13871	DT	denotes	the
T8368	13866-13868	,	denotes	,
T8367	13903-13906	VBD	denotes	was
T8366	13859-13866	RB	denotes	However
T8365	13858-13971	sentence	denotes	However, the ratio of the thrombus to lumen was similar for A/J (0.63 ± 0.03) compared to B6 mice (0.67 ± 0.09).
T8364	13857-13858	.	denotes	.
T8363	13856-13857	-RRB-	denotes	)
T8362	13853-13854	SYM	denotes	=
T8361	13855-13856	CD	denotes	6
T8360	13851-13852	NN	denotes	n
T8359	13849-13851	,	denotes	,
T8358	13842-13843	SYM	denotes	±
T8357	13836-13841	CD	denotes	0.128
T8356	13844-13849	CD	denotes	0.007
T8355	13835-13836	-LRB-	denotes	(
T8354	13830-13834	NNS	denotes	mice
T8353	13827-13829	NN	denotes	B6
T8352	13823-13826	IN	denotes	for
T8351	13818-13822	IN	denotes	than
T8350	13810-13811	SYM	denotes	/
T8349	13811-13812	NN	denotes	J
T8348	13809-13810	NN	denotes	A
T8347	13813-13817	NNS	denotes	mice
T8346	13805-13808	DT	denotes	the
T8345	13802-13804	IN	denotes	in
T8344	13797-13801	JJR	denotes	less
T8343	13783-13796	RB	denotes	significantly
T8342	13777-13778	-RRB-	denotes	)
T8341	13774-13775	SYM	denotes	=
T8340	13776-13777	CD	denotes	6
T8339	13772-13773	NN	denotes	n
T8338	13770-13772	,	denotes	,
T8337	13763-13764	SYM	denotes	±
T8336	13757-13762	CD	denotes	0.066
T8335	13765-13770	CD	denotes	0.007
T8334	13756-13757	-LRB-	denotes	(
T8333	13750-13755	NN	denotes	lumen
T8332	13746-13749	DT	denotes	the
T8331	13743-13745	IN	denotes	of
T8330	13741-13742	-RRB-	denotes	)
T8329	13738-13741	NN	denotes	mm2
T8328	13737-13738	-LRB-	denotes	(
T8327	13779-13782	VBD	denotes	was
T8326	13732-13736	NN	denotes	area
T8325	13728-13731	DT	denotes	The
T8324	13727-13858	sentence	denotes	The area (mm2) of the lumen (0.066 ± 0.007, n = 6) was significantly less in the A/J mice than for B6 mice (0.128 ± 0.007, n = 6).
T8323	13726-13727	.	denotes	.
T8322	13717-13726	JJ	denotes	different
T8321	13706-13716	RB	denotes	noticeably
T8320	13690-13693	CD	denotes	two
T8319	13694-13701	NNS	denotes	strains
T8318	13686-13689	DT	denotes	the
T8317	13683-13685	IN	denotes	in
T8316	13674-13682	NNS	denotes	carotids
T8315	13670-13673	DT	denotes	the
T8314	13667-13669	IN	denotes	of
T8313	13702-13705	VBD	denotes	was
T8312	13662-13666	NN	denotes	size
T8311	13658-13661	DT	denotes	The
T8310	13657-13727	sentence	denotes	The size of the carotids in the two strains was noticeably different.
T8309	13656-13657	.	denotes	.
T8308	13655-13656	-RRB-	denotes	)
T8307	13646-13652	NN	denotes	Figure
T8306	13653-13655	NN	denotes	1A
T8305	13645-13646	-LRB-	denotes	(
T8304	13633-13636	CD	denotes	two
T8303	13637-13644	NNS	denotes	strains
T8302	13629-13632	DT	denotes	the
T8301	13621-13628	IN	denotes	between
T8300	13611-13620	JJ	denotes	different
T8299	13597-13610	RB	denotes	significantly
T8298	13592-13596	VBD	denotes	were
T8297	13576-13585	NN	denotes	occlusion
T8296	13571-13575	JJ	denotes	mean
T8295	13586-13591	NNS	denotes	times
T8294	13567-13570	DT	denotes	The
T8293	13566-13657	sentence	denotes	The mean occlusion times were significantly different between the two strains (Figure 1A).
T8292	13565-13566	.	denotes	.
T8291	13556-13558	NN	denotes	B6
T8290	13559-13565	NN	denotes	strain
T8289	13552-13555	DT	denotes	the
T8288	13547-13551	IN	denotes	from
T8287	13529-13535	JJ	denotes	marked
T8286	13536-13546	NN	denotes	difference
T8285	13527-13528	DT	denotes	a
T8284	13513-13526	VBG	denotes	demonstrating
T8283	13511-13513	,	denotes	,
T8282	13510-13511	-RRB-	denotes	)
T8281	13501-13507	NN	denotes	Figure
T8280	13508-13510	NN	denotes	1C
T8279	13500-13501	-LRB-	denotes	(
T8278	13495-13499	CD	denotes	zero
T8277	13492-13494	IN	denotes	to
T8276	13483-13491	RB	denotes	abruptly
T8275	13462-13467	NN	denotes	blood
T8274	13468-13472	NN	denotes	flow
T8273	13458-13461	DT	denotes	the
T8272	13450-13451	HYPH	denotes	/
T8271	13451-13452	NN	denotes	J
T8270	13449-13450	NN	denotes	A
T8269	13453-13457	NNS	denotes	mice
T8268	13445-13448	DT	denotes	the
T8267	13473-13482	VBD	denotes	decreased
T8266	13441-13444	IN	denotes	for
T8265	13437-13440	CC	denotes	but
T8264	13435-13437	,	denotes	,
T8263	13434-13435	-RRB-	denotes	)
T8262	13425-13431	NN	denotes	Figure
T8261	13432-13434	NN	denotes	1B
T8260	13424-13425	-LRB-	denotes	(
T8259	13416-13418	NN	denotes	B6
T8258	13419-13423	NNS	denotes	mice
T8257	13412-13415	DT	denotes	the
T8256	13408-13411	IN	denotes	for
T8255	13398-13407	NN	denotes	occlusion
T8254	13391-13397	IN	denotes	before
T8253	13374-13381	JJ	denotes	gradual
T8252	13382-13390	NN	denotes	decrease
T8251	13372-13373	DT	denotes	a
T8250	13367-13371	IN	denotes	with
T8249	13359-13366	NN	denotes	pattern
T8248	13357-13358	DT	denotes	a
T8247	13335-13346	NN	denotes	application
T8246	13329-13334	NN	denotes	FeCl3
T8245	13323-13328	IN	denotes	after
T8244	13318-13322	NN	denotes	flow
T8243	13312-13317	NN	denotes	blood
T8242	13309-13311	IN	denotes	of
T8241	13347-13356	VBD	denotes	indicated
T8240	13302-13308	NNS	denotes	curves
T8239	13298-13301	DT	denotes	The
T8238	13297-13566	sentence	denotes	The curves of blood flow after FeCl3 application indicated a pattern with a gradual decrease before occlusion for the B6 mice (Figure 1B), but for the A/J mice the blood flow decreased abruptly to zero (Figure 1C), demonstrating a marked difference from the B6 strain.
T8237	13296-13297	.	denotes	.
T8236	13295-13296	-RRB-	denotes	)
T8235	13291-13292	SYM	denotes	=
T8234	13293-13295	CD	denotes	14
T8233	13289-13290	NN	denotes	n
T8232	13287-13289	,	denotes	,
T8231	13284-13285	SYM	denotes	±
T8230	13282-13283	CD	denotes	5
T8229	13286-13287	CD	denotes	2
T8228	13281-13282	-LRB-	denotes	(
T8227	13278-13279	HYPH	denotes	/
T8226	13279-13280	NN	denotes	J
T8225	13277-13278	NN	denotes	A
T8224	13273-13276	CC	denotes	and
T8223	13268-13269	SYM	denotes	=
T8222	13270-13272	CD	denotes	17
T8221	13266-13267	NN	denotes	n
T8220	13264-13266	,	denotes	,
T8219	13261-13262	SYM	denotes	±
T8218	13258-13260	CD	denotes	10
T8217	13263-13264	CD	denotes	1
T8216	13257-13258	-LRB-	denotes	(
T8215	13254-13256	NN	denotes	B6
T8214	13250-13253	IN	denotes	for
T8213	13248-13249	NN	denotes	%
T8212	13246-13248	CD	denotes	10
T8211	13243-13245	IN	denotes	at
T8210	13238-13242	IN	denotes	than
T8209	13231-13237	JJR	denotes	longer
T8208	13224-13225	NN	denotes	%
T8207	13223-13224	CD	denotes	5
T8206	13220-13222	IN	denotes	at
T8201	13211-13213	,	denotes	,
T8200	13208-13209	SYM	denotes	±
T8199	13206-13207	CD	denotes	8
T8198	13210-13211	CD	denotes	1
T8197	13205-13206	-LRB-	denotes	(
T8196	13202-13203	HYPH	denotes	/
T8195	13203-13204	NN	denotes	J
T8194	13201-13202	NN	denotes	A
T8193	13197-13200	CC	denotes	and
T8192	13195-13196	-RRB-	denotes	)
T8191	13192-13193	SYM	denotes	=
T8190	13194-13195	CD	denotes	3
T8189	13190-13191	NN	denotes	n
T9507	14993-14994	NN	denotes	A
T9506	14989-14992	CC	denotes	and
T9505	14986-14988	NN	denotes	B6
T9504	14997-15004	NNS	denotes	strains
T9503	14982-14985	DT	denotes	the
T9502	14979-14981	IN	denotes	in
T9501	14966-14970	VBD	denotes	were
T9500	14957-14965	NNS	denotes	pathways
T9499	14948-14956	JJ	denotes	specific
T9498	14971-14978	VBN	denotes	altered
T9497	14945-14947	IN	denotes	if
T9496	14935-14944	VB	denotes	determine
T9495	14932-14934	TO	denotes	to
T9494	14926-14931	NN	denotes	order
T9493	15110-15116	VBN	denotes	tested
T9492	14923-14925	IN	denotes	In
T9491	14922-15117	sentence	denotes	In order to determine if specific pathways were altered in the B6 and A/J strains, mice with known alterations in hemostasis, Lepob mice, or thrombosis, Plg-/- and PAI-/- mice, were also tested.
T9490	14921-14922	.	denotes	.
T9489	14920-14921	-RRB-	denotes	)
T9488	14911-14917	NN	denotes	Figure
T9487	14918-14920	NN	denotes	2A
T9486	14910-14911	-LRB-	denotes	(
T9485	14905-14909	NNS	denotes	mice
T9484	14902-14904	NN	denotes	B6
T9483	14899-14901	IN	denotes	to
T9482	14890-14898	VBN	denotes	compared
T9481	14885-14889	NNS	denotes	mice
T9480	14882-14883	HYPH	denotes	/
T8188	13188-13190	,	denotes	,
T8187	13185-13186	SYM	denotes	±
T8186	13182-13184	CD	denotes	15
T8185	13187-13188	CD	denotes	3
T8184	13181-13182	-LRB-	denotes	(
T8183	13178-13180	NN	denotes	B6
T8182	13173-13177	CC	denotes	both
T8181	13169-13172	IN	denotes	for
T8180	13165-13168	NNS	denotes	min
T8179	13164-13165	-LRB-	denotes	(
T8178	13226-13230	VBD	denotes	were
T8177	13149-13158	NN	denotes	occlusion
T8176	13159-13163	NN	denotes	time
T8175	13145-13148	DT	denotes	The
T8174	13144-13297	sentence	denotes	The occlusion time (min for both B6 (15 ± 3, n = 3) and A/J (8 ± 1, n = 3) at 5% were longer than at 10% for B6 (10 ± 1, n = 17 and A/J (5 ± 2, n = 14).
T8173	13143-13144	.	denotes	.
T8172	13137-13138	NN	denotes	%
T8171	13135-13137	CD	denotes	10
T8170	13139-13143	NN	denotes	dose
T8169	13131-13134	DT	denotes	the
T8168	13126-13130	IN	denotes	with
T8167	13123-13125	IN	denotes	as
T8166	13110-13114	JJ	denotes	same
T8165	13115-13122	NNS	denotes	results
T8164	13106-13109	DT	denotes	the
T8163	13104-13106	,	denotes	,
T8162	13100-13104	NNS	denotes	mice
T8161	13097-13099	NN	denotes	B6
T8160	13093-13096	DT	denotes	the
T8159	13088-13092	IN	denotes	than
T8108	12913-12915	NN	denotes	1A
T8107	12905-12906	-LRB-	denotes	(
T8106	12900-12904	NNS	denotes	mice
T8105	12897-12898	HYPH	denotes	/
T8104	12896-12897	NN	denotes	A
T8103	12898-12899	NN	denotes	J
T8102	12892-12895	DT	denotes	the
T8101	12888-12891	CC	denotes	and
T8100	12885-12887	NN	denotes	B6
T8099	12881-12884	DT	denotes	the
T8098	12873-12880	IN	denotes	between
T8097	12863-12866	VBD	denotes	was
T8096	12858-12862	NN	denotes	time
T8095	12848-12857	NN	denotes	occlusion
T8094	12839-12847	NN	denotes	thrombus
T8093	12830-12838	JJ	denotes	arterial
T8092	12827-12829	IN	denotes	in
T8091	12867-12872	VBN	denotes	found
T8090	12809-12815	JJ	denotes	marked
T8089	12816-12826	NN	denotes	difference
T8088	12807-12808	DT	denotes	A
T8087	12806-12917	sentence	denotes	A marked difference in arterial thrombus occlusion time was found between the B6 and the A/J mice (Figure 1A).
T8086	12805-12806	.	denotes	.
T8085	12792-12805	NN	denotes	investigation
T8084	12786-12791	IN	denotes	under
T8083	12772-12777	NN	denotes	mouse
T8082	12769-12770	HYPH	denotes	/
T8081	12770-12771	NN	denotes	J
T8080	12768-12769	NN	denotes	A
T8079	12764-12767	CC	denotes	and
T8078	12761-12763	NN	denotes	B6
T8077	12778-12785	NNS	denotes	strains
T8076	12757-12760	DT	denotes	the
T8075	12754-12756	IN	denotes	in
T8074	12735-12744	JJ	denotes	occlusive
T8073	12745-12753	NN	denotes	thrombus
T8072	12732-12734	DT	denotes	an
T8071	12725-12731	VB	denotes	induce
T8070	12722-12724	TO	denotes	to
T8069	12713-12716	VBD	denotes	was
T8068	12711-12713	,	denotes	,
T8067	12695-12705	NN	denotes	thrombosis
T8066	12686-12694	JJ	denotes	arterial
T8065	12671-12672	HYPH	denotes	-
T8064	12672-12685	VBN	denotes	characterized
T8063	12667-12671	JJ	denotes	well
T8062	12706-12711	NN	denotes	model
T8061	12665-12666	DT	denotes	a
T8060	12663-12665	,	denotes	,
T8059	12662-12663	-RRB-	denotes	]
T8058	12660-12662	CD	denotes	24
T8057	12659-12660	-LRB-	denotes	[
T8056	12717-12721	VBN	denotes	used
T8055	12646-12652	NN	denotes	injury
T8054	12639-12645	NN	denotes	artery
T8053	12631-12638	JJ	denotes	cartoid
T8052	12625-12630	NN	denotes	FeCl3
T8051	12653-12658	NN	denotes	model
T8050	12621-12624	DT	denotes	The
T8049	12620-12806	sentence	denotes	The FeCl3 cartoid artery injury model [24], a well-characterized arterial thrombosis model, was used to induce an occlusive thrombus in the B6 and A/J mouse strains under investigation.
T8048	12613-12614	HYPH	denotes	/
T8047	12614-12615	NN	denotes	J
T8046	12612-12613	NN	denotes	A
T8045	12608-12611	CC	denotes	and
T8044	12616-12620	NNS	denotes	mice
T8043	12605-12607	NN	denotes	B6
T8042	12602-12604	IN	denotes	in
T8041	12592-12601	NN	denotes	formation
T8040	12583-12591	NN	denotes	thrombus
T8039	12574-12582	JJ	denotes	arterial
T8038	12571-12573	IN	denotes	in
T8037	12559-12570	NNS	denotes	differences
T8036	12552-12558	JJ	denotes	Marked
T8418	14057-14061	NNS	denotes	mice
T8417	14054-14056	NN	denotes	B6
T8416	14051-14053	IN	denotes	to
T8415	14042-14050	VBN	denotes	compared
T8414	14037-14041	WRB	denotes	when
T8413	14029-14030	HYPH	denotes	/
T8412	14030-14031	NN	denotes	J
T8411	14028-14029	NN	denotes	A
T8410	14032-14036	NNS	denotes	mice
T8409	14024-14027	DT	denotes	the
T8408	14021-14023	IN	denotes	in
T8407	14016-14020	JJR	denotes	less
T8406	14014-14015	NN	denotes	%
T8405	14012-14014	CD	denotes	14
T8404	14005-14006	-RRB-	denotes	]
T8403	14003-14005	CD	denotes	25
T8402	14002-14003	-LRB-	denotes	[
T8401	14007-14011	VBD	denotes	were
T8400	13989-13995	NN	denotes	stress
T8399	13983-13988	NN	denotes	sheer
T8398	13996-14001	NNS	denotes	rates
T8397	13972-13982	VBN	denotes	Calculated
T8396	13971-14062	sentence	denotes	Calculated sheer stress rates [25] were 14% less in the A/J mice when compared to B6 mice.
T8395	13970-13971	.	denotes	.
T8394	13969-13970	-RRB-	denotes	)
T8393	13963-13964	SYM	denotes	±
T8392	13958-13962	CD	denotes	0.67
T8391	13965-13969	CD	denotes	0.09
T8390	13957-13958	-LRB-	denotes	(
T8389	13952-13956	NNS	denotes	mice
T8388	13949-13951	NN	denotes	B6
T8387	13946-13948	IN	denotes	to
T8386	13937-13945	VBN	denotes	compared
T8385	13935-13936	-RRB-	denotes	)
T8384	13929-13930	SYM	denotes	±
T8383	13924-13928	CD	denotes	0.63
T8382	13931-13935	CD	denotes	0.03
T8381	13923-13924	-LRB-	denotes	(
T8380	13920-13921	HYPH	denotes	/
T8379	13921-13922	NN	denotes	J
T8378	13919-13920	NN	denotes	A
T8377	13915-13918	IN	denotes	for
T8376	13907-13914	JJ	denotes	similar
T8375	13897-13902	NN	denotes	lumen
T8158	13085-13086	HYPH	denotes	/
T8157	13084-13085	NN	denotes	A
T8156	13086-13087	NN	denotes	J
T8155	13080-13083	DT	denotes	the
T8154	13077-13079	IN	denotes	in
T8153	13071-13076	JJR	denotes	lower
T8152	13067-13070	VBD	denotes	was
T8151	13052-13061	NN	denotes	occlusion
T8150	13062-13066	NN	denotes	time
T8149	13048-13051	DT	denotes	the
T8148	13044-13047	CC	denotes	and
T8147	13036-13038	NN	denotes	B6
T8146	13032-13035	CC	denotes	and
T8145	13029-13030	HYPH	denotes	/
T8144	13030-13031	NN	denotes	J
T8143	13028-13029	NN	denotes	A
T8142	13039-13043	NNS	denotes	mice
T8141	13024-13027	DT	denotes	the
T8140	13021-13023	IN	denotes	in
T8139	13010-13013	VBD	denotes	was
T8138	13004-13009	NN	denotes	FeCl3
T8137	13001-13003	IN	denotes	of
T8136	13014-13020	VBN	denotes	tested
T8135	12994-12995	NN	denotes	%
T8134	12993-12994	CD	denotes	5
T8133	12996-13000	NN	denotes	dose
T8132	12991-12992	DT	denotes	A
T8131	12990-13144	sentence	denotes	A 5% dose of FeCl3 was tested in the A/J and B6 mice and the occlusion time was lower in the A/J than the B6 mice, the same results as with the 10% dose.
T8130	12989-12990	.	denotes	.
T8129	12982-12984	NN	denotes	B6
T8128	12985-12989	NNS	denotes	mice
T8127	12978-12981	DT	denotes	the
T8126	12974-12977	IN	denotes	for
T8125	12969-12973	IN	denotes	than
T8124	12964-12968	JJR	denotes	less
T8123	12957-12963	RB	denotes	2-fold
T8122	12945-12946	HYPH	denotes	/
T8121	12946-12947	NN	denotes	J
T8120	12944-12945	NN	denotes	A
T8119	12948-12952	NNS	denotes	mice
T8118	12940-12943	DT	denotes	the
T8117	12937-12939	IN	denotes	in
T8116	12953-12956	VBD	denotes	was
T8115	12922-12931	NN	denotes	occlusion
T8114	12932-12936	NN	denotes	time
T8113	12918-12921	DT	denotes	The
T8112	12917-12990	sentence	denotes	The occlusion time in the A/J mice was 2-fold less than for the B6 mice.
T8111	12916-12917	.	denotes	.
T8110	12915-12916	-RRB-	denotes	)
T8109	12906-12912	NN	denotes	Figure
T7238	12219-12225	NNP	denotes	Newman
T7237	12232-12241	NN	denotes	post-test
T7236	12217-12218	DT	denotes	a
T7235	12213-12216	CC	denotes	and
T7234	12202-12203	HYPH	denotes	-
T7233	12203-12206	NN	denotes	way
T7232	12199-12202	CD	denotes	one
T7231	12207-12212	NN	denotes	ANOVA
T7230	12197-12198	DT	denotes	a
T7229	12194-12196	IN	denotes	by
T7228	12178-12182	VBD	denotes	were
T7227	12171-12172	SYM	denotes	-
T7226	12170-12171	HYPH	denotes	/
T7225	12169-12170	SYM	denotes	-
T7224	12168-12169	CD	denotes	1
T7223	12167-12168	HYPH	denotes	-
T7222	12164-12167	NN	denotes	PAI
T7221	12162-12164	,	denotes	,
T7220	12157-12162	NN	denotes	Lepob
T7219	12155-12157	,	denotes	,
T7218	12173-12177	NNS	denotes	mice
T7217	12153-12155	NN	denotes	B6
T7216	12147-12152	IN	denotes	among
T7215	12183-12193	VBN	denotes	determined
T7214	12135-12146	NNS	denotes	Differences
T7213	12134-12242	sentence	denotes	Differences among B6, Lepob, PAI-1-/- mice were determined by a one-way ANOVA and a Newman-Keuls post-test.
T7212	12133-12134	.	denotes	.
T7211	12128-12129	HYPH	denotes	-
T7210	12127-12128	NN	denotes	t
T7209	12119-12120	HYPH	denotes	-
T7208	12120-12126	VBN	denotes	tailed
T7207	12116-12119	CD	denotes	two
T7206	12129-12133	NN	denotes	test
T7205	12114-12115	DT	denotes	a
T7204	12109-12113	IN	denotes	with
T7203	12096-12099	VBD	denotes	was
T7202	12082-12083	SYM	denotes	-
T7201	12081-12082	HYPH	denotes	/
T7200	12080-12081	SYM	denotes	-
T7199	12077-12080	NN	denotes	Plg
T7198	12073-12076	CC	denotes	and
T7197	12071-12072	-RRB-	denotes	)
T7196	12069-12071	NN	denotes	WT
T7195	12068-12069	-LRB-	denotes	(
T7194	12084-12095	NNS	denotes	littermates
T7193	12062-12063	HYPH	denotes	-
T7192	12063-12067	NN	denotes	type
T7191	12058-12062	JJ	denotes	wild
T7190	12050-12057	IN	denotes	between
T7189	12046-12049	CC	denotes	and
T7188	12038-12040	NN	denotes	B6
T7187	12034-12037	CC	denotes	and
T7186	12041-12045	NNS	denotes	mice
T7185	12031-12032	HYPH	denotes	/
T7184	12032-12033	NN	denotes	J
T7183	12030-12031	NN	denotes	A
T7182	12022-12029	IN	denotes	between
T7181	12010-12021	NNS	denotes	comparisons
T7180	12006-12009	IN	denotes	for
T7179	12100-12108	VBN	denotes	compared
T7178	11985-11996	JJ	denotes	statistical
T7177	11997-12005	NN	denotes	analysis
T7176	11981-11984	DT	denotes	The
T7175	11980-12134	sentence	denotes	The statistical analysis for comparisons between A/J and B6 mice and between wild-type (WT) and Plg-/- littermates was compared with a two-tailed t-test.
T7174	11979-11980	.	denotes	.
T7173	11974-11975	SYM	denotes	±
T6823	11499-11503	VBD	denotes	were
T6822	11495-11498	NN	denotes	OCT
T6821	11492-11494	IN	denotes	in
T6820	11483-11491	NNS	denotes	carotids
T6819	11475-11482	JJ	denotes	injured
T6818	11472-11474	CC	denotes	or
T6817	11504-11513	VBN	denotes	sectioned
T6816	11459-11465	VBN	denotes	frozen
T6815	11466-11471	NNS	denotes	tails
T6814	11455-11458	DT	denotes	The
T6813	11454-11595	sentence	denotes	The frozen tails or injured carotids in OCT were sectioned at 5 μm thickness and stained with Masson's Trichrome (HT 15, Sigma Diagnostics).
T6812	11425-11445	NN	denotes	immunohistochemistry
T6811	11421-11424	CC	denotes	and
T6810	11446-11454	NN	denotes	analysis
T6809	11407-11420	JJ	denotes	Histochemical
T7277	12408-12410	IN	denotes	of
T7276	12457-12467	VBN	denotes	determined
T7275	12402-12407	NN	denotes	level
T7274	12398-12401	DT	denotes	the
T7273	12394-12397	CC	denotes	and
T7272	12387-12388	HYPH	denotes	-
T7271	12386-12387	NN	denotes	t
T7270	12388-12393	NNS	denotes	tests
T7269	12380-12381	HYPH	denotes	-
T7268	12381-12385	NN	denotes	tail
T7267	12377-12380	CD	denotes	two
T7266	12372-12376	IN	denotes	with
T7265	12356-12360	VBD	denotes	were
T7264	12352-12355	NN	denotes	CSS
T7263	12348-12351	CC	denotes	and
T7262	12343-12347	NNS	denotes	mice
T7261	12340-12342	NN	denotes	B6
T7260	12332-12339	IN	denotes	between
T7259	12320-12331	NNS	denotes	comparisons
T7258	12316-12319	IN	denotes	for
T7257	12361-12371	VBN	denotes	determined
T7256	12295-12306	JJ	denotes	statistical
T7255	12307-12315	NN	denotes	analysis
T7254	12291-12294	DT	denotes	The
T7253	12290-12541	sentence	denotes	The statistical analysis for comparisons between B6 mice and CSS were determined with two-tail t-tests and the level of the significant P-values (see figure legends) determined with a Bonferroni correction to account for multihypothesis testing [13].
T7252	12289-12290	.	denotes	.
T7251	12278-12289	JJ	denotes	significant
T7250	12263-12266	VBD	denotes	was
T7249	12258-12262	CD	denotes	0.05
T7248	12256-12257	SYM	denotes	<
T7247	12254-12255	NN	denotes	P
T7246	12251-12253	IN	denotes	of
T7245	12267-12277	VBN	denotes	considered
T7244	12245-12250	NN	denotes	value
T7243	12243-12244	DT	denotes	A
T7242	12242-12290	sentence	denotes	A value of P < 0.05 was considered significant.
T7241	12241-12242	.	denotes	.
T7240	12225-12226	HYPH	denotes	-
T7239	12226-12231	NNP	denotes	Keuls
T6616	11318-11320	DT	denotes	an
T6615	11313-11317	IN	denotes	with
T6614	11302-11312	NN	denotes	fibrinogen
T6613	11298-11301	CC	denotes	and
T6612	11296-11298	,	denotes	,
T6611	11295-11296	-RRB-	denotes	)
T6610	11293-11295	NNP	denotes	MI
T6609	11291-11293	,	denotes	,
T6608	11281-11291	NNP	denotes	Southfield
T6607	11279-11281	,	denotes	,
T6606	11258-11267	NNP	denotes	Molecular
T6605	11268-11279	NNPS	denotes	Innovations
T6604	11257-11258	-LRB-	denotes	(
T6603	11242-11247	NN	denotes	mouse
T6602	11248-11256	NN	denotes	antibody
T6601	11240-11241	DT	denotes	a
T6600	11235-11239	IN	denotes	with
T6599	11225-11234	NN	denotes	detection
T6598	11221-11224	CC	denotes	and
T6597	11207-11214	NN	denotes	capture
T6596	11199-11206	NN	denotes	plasmin
T6595	11215-11220	NN	denotes	assay
T6594	11197-11198	DT	denotes	a
T6593	11192-11196	IN	denotes	with
T6592	11177-11180	VBD	denotes	was
T6591	11181-11191	VBN	denotes	determined
T6590	11164-11165	HYPH	denotes	-
T6589	11162-11164	NN	denotes	α2
T6588	11156-11161	NN	denotes	mouse
T6587	11165-11176	NN	denotes	antiplasmin
T6586	11149-11155	JJ	denotes	active
T6585	11136-11148	RB	denotes	Functionally
T6584	11135-11405	sentence	denotes	Functionally active mouse α2-antiplasmin was determined with a plasmin capture assay and detection with a mouse antibody (Molecular Innovations, Southfield, MI), and fibrinogen with an ELISA assay with antibodies that recognize mouse fibrinogen (Hyphen BioMed, France).
T6583	11134-11135	.	denotes	.
T6582	11126-11129	VBD	denotes	was
T6581	11121-11125	NNS	denotes	mice
T6580	11107-11110	NN	denotes	Plg
T6579	11104-11106	CC	denotes	or
T6578	11102-11103	CD	denotes	1
T6577	11101-11102	HYPH	denotes	-
T6576	11111-11120	JJ	denotes	deficient
T6575	11098-11101	NN	denotes	PAI
T6574	11093-11097	IN	denotes	from
T6573	11086-11092	NN	denotes	plasma
T6572	11084-11086	,	denotes	,
T6571	11078-11084	NNS	denotes	assays
T6570	11072-11077	DT	denotes	these
T6569	11069-11071	IN	denotes	in
T6568	11051-11059	JJ	denotes	negative
T6567	11060-11068	NNS	denotes	controls
T6566	11047-11050	DT	denotes	the
T6565	11130-11134	VBN	denotes	used
T6564	11043-11046	IN	denotes	For
T6563	11042-11135	sentence	denotes	For the negative controls in these assays, plasma from PAI-1 or Plg deficient mice was used.
T6562	11041-11042	.	denotes	.
T6561	11040-11041	-RRB-	denotes	]
T6560	11038-11040	CD	denotes	23
T6559	11037-11038	-LRB-	denotes	[
T6558	11025-11036	NN	denotes	degradation
T6557	11018-11024	NN	denotes	fibrin
T6556	11015-11017	IN	denotes	by
T6555	11004-11014	VBN	denotes	determined
T6554	10982-10994	JJ	denotes	fibrinolytic
T6553	10995-11003	NN	denotes	activity
T6552	10978-10981	DT	denotes	the
T6551	10974-10977	CC	denotes	and
T6550	10972-10973	-RRB-	denotes	]
T6549	10970-10972	CD	denotes	22
T6548	10969-10970	-LRB-	denotes	[
T6547	10951-10962	JJ	denotes	chromogenic
T6546	10963-10968	NN	denotes	assay
T6545	10949-10950	DT	denotes	a
T6544	10944-10948	IN	denotes	with
T6543	10929-10932	VBD	denotes	was
T6542	10933-10943	VBN	denotes	determined
T6541	10925-10928	NN	denotes	Plg
T6540	10924-11042	sentence	denotes	Plg was determined with a chromogenic assay [22] and the fibrinolytic activity determined by fibrin degradation [23].
T6539	10923-10924	.	denotes	.
T6538	10922-10923	-RRB-	denotes	)
T6537	10920-10922	NN	denotes	mL
T6536	10919-10920	SYM	denotes	/
T6535	10912-10913	SYM	denotes	–
T6534	10913-10916	CD	denotes	3.5
T6533	10911-10912	CD	denotes	0
T6532	10917-10919	NNS	denotes	ng
T6531	10910-10911	-LRB-	denotes	(
T6530	10901-10909	JJ	denotes	standard
T6529	10897-10900	DT	denotes	the
T6528	10894-10896	IN	denotes	as
T6527	10892-10893	-RRB-	denotes	)
T6526	10872-10880	NNP	denotes	American
T6525	10881-10892	NNP	denotes	Diagnostica
T6524	10871-10872	-LRB-	denotes	(
T6523	10869-10870	CD	denotes	1
T6522	10868-10869	HYPH	denotes	-
T6521	10865-10868	NN	denotes	PAI
T6520	10859-10864	NN	denotes	mouse
T6519	10855-10858	CC	denotes	and
T6518	10838-10845	NN	denotes	capture
T6517	10846-10854	NN	denotes	antibody
T6516	10834-10837	DT	denotes	the
T6515	10831-10833	IN	denotes	as
T6514	10829-10830	-RRB-	denotes	)
T6513	10809-10817	NNP	denotes	American
T6512	10818-10829	NNP	denotes	Diagnostica
T6511	10808-10809	-LRB-	denotes	(
T6510	10806-10807	CD	denotes	1
T6509	10805-10806	HYPH	denotes	-
T6508	10796-10801	NN	denotes	mouse
T6507	10791-10795	AFX	denotes	anti
T6506	10790-10791	HYPH	denotes	-
T6505	10802-10805	NN	denotes	PAI
T6504	10785-10790	NN	denotes	sheep
T6503	10779-10784	VBG	denotes	using
T6502	10777-10778	-RRB-	denotes	]
T6501	10775-10777	CD	denotes	21
T6500	10774-10775	-LRB-	denotes	[
T6499	10768-10773	NNP	denotes	ELISA
T6498	10765-10767	IN	denotes	by
T6497	10750-10753	VBD	denotes	was
T6496	10754-10764	VBN	denotes	determined
T6495	10728-10735	NN	denotes	antigen
T6494	10726-10727	CD	denotes	1
T6493	10725-10726	HYPH	denotes	-
T6492	10736-10749	NN	denotes	concentration
T6491	10722-10725	NN	denotes	PAI
T6490	10721-10924	sentence	denotes	PAI-1 antigen concentration was determined by ELISA [21] using sheep-anti mouse PAI-1 (American Diagnostica) as the capture antibody and mouse PAI-1 (American Diagnostica) as the standard (0–3.5 ng/mL).
T6489	10720-10721	.	denotes	.
T6488	10719-10720	-RRB-	denotes	]
T6487	10717-10719	CD	denotes	20
T6486	10716-10717	-LRB-	denotes	[
T6485	10713-10715	FW	denotes	al
T6484	10710-10712	FW	denotes	et
T6483	10701-10709	NNP	denotes	Chandler
T6482	10698-10700	IN	denotes	of
T6481	10691-10697	NN	denotes	method
T6480	10687-10690	DT	denotes	the
T6479	10684-10686	IN	denotes	to
T6478	10674-10683	VBG	denotes	according
T6477	10659-10662	VBD	denotes	was
T6476	10663-10673	VBN	denotes	determined
T6475	10648-10649	CD	denotes	1
T6474	10647-10648	HYPH	denotes	-
T6473	10650-10658	NN	denotes	activity
T6472	10644-10647	NN	denotes	PAI
T6471	10643-10721	sentence	denotes	PAI-1 activity was determined according to the method of Chandler et al [20].
T6470	10642-10643	.	denotes	.
T6469	10641-10642	-RRB-	denotes	)
T6468	10629-10631	,	denotes	,
T6467	10622-10629	NNP	denotes	SCA2000
T6466	10631-10641	NNP	denotes	Synbiotics
T6465	10621-10622	-LRB-	denotes	(
T6464	10600-10611	NNP	denotes	Coagulation
T6463	10586-10599	VBN	denotes	precalibrated
T6462	10612-10620	NNP	denotes	Analyzer
T6461	10582-10585	DT	denotes	the
T6460	10577-10581	IN	denotes	into
T6459	10568-10576	VBN	denotes	inserted
T6458	10564-10567	CC	denotes	and
T6457	10547-10548	-RRB-	denotes	)
T6456	10543-10547	NN	denotes	aPTT
T6455	10542-10543	-LRB-	denotes	(
T6454	10522-10536	NN	denotes	thromboplastin
T6453	10514-10521	JJ	denotes	partial
T6452	10537-10541	NN	denotes	time
T6451	10504-10513	VBN	denotes	activated
T6450	10501-10503	CC	denotes	or
T6449	10499-10500	-RRB-	denotes	)
T6448	10497-10499	NN	denotes	PT
T6447	10496-10497	-LRB-	denotes	(
T6446	10549-10563	NNS	denotes	determinations
T6445	10491-10495	NN	denotes	time
T6444	10479-10490	NN	denotes	prothrombin
T6443	10475-10478	IN	denotes	for
T6442	10473-10474	-RRB-	denotes	)
T6441	10463-10473	NNP	denotes	Synbiotics
T6440	10462-10463	-LRB-	denotes	(
T6439	10448-10455	NN	denotes	reagent
T6438	10456-10461	NN	denotes	strip
T6437	10446-10447	DT	denotes	a
T6436	10443-10445	IN	denotes	on
T6435	10424-10435	RB	denotes	immediately
T6434	10418-10423	NN	denotes	blood
T6433	10415-10417	IN	denotes	of
T6432	10436-10442	VBN	denotes	placed
T6431	10410-10414	NN	denotes	drop
T6430	10408-10409	DT	denotes	a
T6429	10404-10407	CC	denotes	and
T6428	10402-10404	,	denotes	,
T6427	10387-10396	JJ	denotes	capillary
T6426	10397-10402	NNS	denotes	tubes
T6425	10378-10386	JJ	denotes	uncoated
T6424	10373-10377	IN	denotes	into
T6423	10359-10366	JJ	denotes	orbital
T6422	10367-10372	NN	denotes	sinus
T6421	10355-10358	DT	denotes	the
T6420	10350-10354	IN	denotes	from
T6419	10345-10349	VBN	denotes	bled
T6418	10343-10345	,	denotes	,
T6417	10342-10343	-RRB-	denotes	)
T6416	10336-10342	NNP	denotes	Abbott
T6415	10335-10336	-LRB-	denotes	(
T6414	10324-10334	NN	denotes	Isoflurane
T6413	10319-10323	IN	denotes	with
T6412	10301-10305	VBD	denotes	were
T6411	10306-10318	VBN	denotes	anesthetized
T6410	10296-10300	NNS	denotes	Mice
T6409	10295-10643	sentence	denotes	Mice were anesthetized with Isoflurane (Abbott), bled from the orbital sinus into uncoated capillary tubes, and a drop of blood immediately placed on a reagent strip (Synbiotics) for prothrombin time (PT) or activated partial thromboplastin time (aPTT) determinations and inserted into the precalibrated Coagulation Analyzer (SCA2000, Synbiotics).
T6408	10287-10288	CD	denotes	1
T6407	10286-10287	HYPH	denotes	-
T6406	10283-10286	NN	denotes	PAI
T6405	10279-10282	CC	denotes	and
T6404	10266-10278	JJ	denotes	fibrinolytic
T6403	10264-10266	,	denotes	,
T6402	10254-10264	NN	denotes	fibrinogen
T6401	10252-10254	,	denotes	,
T6400	10240-10241	HYPH	denotes	-
T6399	10241-10252	NN	denotes	antiplasmin
T6398	10238-10240	NN	denotes	α2
T6397	10236-10238	,	denotes	,
T6396	10233-10236	NN	denotes	Plg
T6395	10231-10233	,	denotes	,
T6394	10289-10295	NNS	denotes	assays
T6393	10220-10231	NN	denotes	Coagulation
T5517	9647-9648	.	denotes	.
T5516	9635-9641	NN	denotes	injury
T5515	9626-9634	JJ	denotes	vascular
T5514	9642-9647	NN	denotes	model
T5513	9622-9625	DT	denotes	the
T5512	9619-9621	IN	denotes	in
T5511	9607-9611	VBD	denotes	were
T5510	9612-9618	VBN	denotes	tested
T5509	9602-9606	WDT	denotes	that
T5508	9597-9601	NNS	denotes	mice
T5507	9593-9596	DT	denotes	the
T5506	9587-9592	IN	denotes	among
T5505	9580-9586	NN	denotes	weight
T5504	9575-9579	NN	denotes	body
T5503	9572-9574	IN	denotes	in
T5502	9561-9571	NN	denotes	difference
T5465	9388-9393	IN	denotes	after
T5464	9424-9431	VBN	denotes	reached
T5463	9384-9387	NNS	denotes	min
T5462	9376-9383	JJ	denotes	several
T5461	9370-9375	IN	denotes	until
T5460	9361-9369	NN	denotes	baseline
T5459	9357-9360	DT	denotes	the
T5458	9354-9356	IN	denotes	of
T5457	9340-9353	NN	denotes	establishment
T5456	9336-9339	DT	denotes	the
T5455	9331-9335	IN	denotes	from
T5454	9325-9330	NN	denotes	place
T5453	9322-9324	IN	denotes	in
T5452	9318-9321	VBD	denotes	was
T5451	9307-9311	NN	denotes	flow
T5450	9312-9317	NN	denotes	probe
T5449	9303-9306	DT	denotes	The
T5448	9302-9476	sentence	denotes	The flow probe was in place from the establishment of the baseline until several min after the stable occlusion had been reached or stopped at 30 min if it had not occluded.
T5447	9301-9302	.	denotes	.
T5446	9300-9301	-RRB-	denotes	)
T5445	9290-9295	NN	denotes	blood
T5444	9296-9300	NN	denotes	flow
T5443	9282-9289	NN	denotes	minimum
T5442	9281-9282	-LRB-	denotes	(
T5441	9274-9280	NN	denotes	artery
T5440	9270-9273	DT	denotes	the
T5439	9267-9269	IN	denotes	of
T5438	9257-9266	NN	denotes	occlusion
T5437	9253-9256	DT	denotes	the
T5436	9250-9252	IN	denotes	to
T5435	9235-9240	NN	denotes	FeCl3
T5434	9241-9249	NN	denotes	solution
T5433	9231-9234	DT	denotes	the
T5432	9228-9230	IN	denotes	of
T5431	9219-9227	NN	denotes	addition
T5430	9215-9218	DT	denotes	the
T5429	9210-9214	IN	denotes	from
T5428	9195-9198	VBD	denotes	was
T5427	9199-9209	VBN	denotes	determined
T5426	9190-9194	NN	denotes	time
T5425	9180-9189	NN	denotes	Occlusion
T5424	9179-9302	sentence	denotes	Occlusion time was determined from the addition of the FeCl3 solution to the occlusion of the artery (minimum blood flow).
T5423	9178-9179	.	denotes	.
T5422	9175-9178	NNS	denotes	min
T5421	9173-9174	CD	denotes	3
T5420	9169-9172	IN	denotes	for
T5419	9154-9161	JJ	denotes	carotid
T5418	9162-9168	NN	denotes	artery
T5417	9150-9153	DT	denotes	the
T5416	9147-9149	IN	denotes	of
T5415	9139-9146	NN	denotes	surface
T5414	9135-9138	DT	denotes	the
T5413	9132-9134	IN	denotes	to
T5412	9120-9123	VBD	denotes	was
T5411	9111-9119	NN	denotes	solution
T5410	9105-9110	NN	denotes	FeCl3
T5409	9103-9104	NN	denotes	%
T5408	9101-9103	CD	denotes	10
T5407	9096-9100	IN	denotes	with
T5406	9086-9095	VBN	denotes	saturated
T5405	9080-9085	NN	denotes	paper
T5404	9073-9079	NN	denotes	filter
T5403	9070-9072	IN	denotes	of
T5402	9061-9063	NN	denotes	mm
T5401	9057-9058	SYM	denotes	×
T5400	9059-9060	CD	denotes	2
T5399	9053-9056	CD	denotes	0.5
T5398	9064-9069	NN	denotes	strip
T5397	9051-9052	DT	denotes	a
T5396	9049-9051	,	denotes	,
T5395	9124-9131	VBN	denotes	applied
T5394	9038-9041	VBD	denotes	was
T5393	9022-9028	JJ	denotes	stable
T5392	9029-9037	NN	denotes	baseline
T5391	9020-9021	DT	denotes	a
T5390	9042-9049	VBN	denotes	reached
T5389	9015-9019	WRB	denotes	when
T5388	9011-9014	CC	denotes	and
T5387	9004-9010	NN	denotes	artery
T5386	9000-9003	DT	denotes	the
T5385	8994-8999	IN	denotes	under
T5384	8983-8986	VBD	denotes	was
T5383	8981-8982	-RRB-	denotes	)
T5382	8969-8974	NN	denotes	model
T5381	8967-8969	,	denotes	,
T5380	8960-8967	NNP	denotes	Systems
T5379	8950-8959	NNP	denotes	Transonic
T5378	8975-8981	NN	denotes	0.5PSB
T5377	8949-8950	-LRB-	denotes	(
T5376	8987-8993	VBN	denotes	placed
T5375	8938-8942	NN	denotes	flow
T5374	8943-8948	NN	denotes	probe
T5373	8934-8937	DT	denotes	The
T5372	8933-9179	sentence	denotes	The flow probe (Transonic Systems, model 0.5PSB) was placed under the artery and when a stable baseline was reached, a 0.5 × 2 mm strip of filter paper saturated with 10% FeCl3 solution was applied to the surface of the carotid artery for 3 min.
T5371	8932-8933	.	denotes	.
T5370	8922-8932	NN	denotes	dissection
T5369	8916-8921	JJ	denotes	blunt
T5368	8913-8915	IN	denotes	by
T5367	8904-8912	VBN	denotes	isolated
T5366	8889-8896	JJ	denotes	carotid
T5365	8882-8888	JJ	denotes	common
T5364	8877-8881	JJ	denotes	left
T5363	8897-8903	NN	denotes	artery
T5362	8873-8876	DT	denotes	the
T5361	8869-8872	CC	denotes	and
T5360	8860-8863	VBD	denotes	was
T5359	8864-8868	VBN	denotes	made
T5358	8842-8850	JJ	denotes	cervical
T5357	8834-8841	NN	denotes	midline
T5356	8851-8859	NN	denotes	incision
T5355	8832-8833	DT	denotes	a
T5354	8830-8832	,	denotes	,
T5353	8829-8830	-RRB-	denotes	)
T5352	8827-8829	NN	denotes	kg
T5351	8826-8827	SYM	denotes	/
T5350	8822-8823	CD	denotes	5
T5349	8820-8822	,	denotes	,
T5348	8818-8820	NN	denotes	kg
T5347	8817-8818	SYM	denotes	/
T5346	8815-8817	NNS	denotes	mg
T5345	8812-8814	CD	denotes	80
T5344	8824-8826	NNS	denotes	mg
T5343	8811-8812	-LRB-	denotes	(
T5342	8801-8802	HYPH	denotes	/
T5341	8802-8810	NN	denotes	xylazine
T5340	8793-8801	NN	denotes	ketamine
T5339	8788-8792	IN	denotes	with
T5338	8770-8774	VBD	denotes	were
T5337	8775-8787	VBN	denotes	anesthetized
T5336	8765-8769	NNS	denotes	Mice
T5335	8764-8933	sentence	denotes	Mice were anesthetized with ketamine/xylazine (80 mg/kg, 5 mg/kg), a midline cervical incision was made and the left common carotid artery isolated by blunt dissection.
T5334	8763-8764	.	denotes	.
T5333	8751-8754	VBD	denotes	was
T5332	8749-8750	-RRB-	denotes	]
T5331	8746-8747	,	denotes	,
T5330	8744-8746	CD	denotes	18
T5329	8747-8749	CD	denotes	19
T5328	8743-8744	-LRB-	denotes	[
T5327	8736-8742	NN	denotes	injury
T5326	8729-8735	NN	denotes	vessel
T5325	8726-8728	IN	denotes	of
T5324	8718-8719	-RRB-	denotes	)
T5323	8713-8718	NN	denotes	FeCl3
T5322	8712-8713	-LRB-	denotes	(
T5321	8703-8711	NN	denotes	chloride
T5320	8696-8702	JJ	denotes	ferric
T5319	8720-8725	NN	denotes	model
T5318	8694-8695	DT	denotes	a
T5317	8692-8694	,	denotes	,
T5316	8678-8685	NN	denotes	carotid
T5315	8686-8692	NN	denotes	artery
T5314	8674-8677	DT	denotes	the
T5313	8671-8673	IN	denotes	in
T5312	8661-8670	NN	denotes	formation
T5311	8650-8660	NN	denotes	thrombosis
T5310	8755-8763	VBN	denotes	employed
T5309	8643-8649	VB	denotes	induce
T5308	8640-8642	TO	denotes	To
T5307	8639-8764	sentence	denotes	To induce thrombosis formation in the carotid artery, a ferric chloride (FeCl3) model of vessel injury [18,19] was employed.
T5306	8633-8639	NN	denotes	injury
T5305	8624-8632	JJ	denotes	Vascular
T5870	10217-10218	.	denotes	.
T5869	10202-10208	JJ	denotes	second
T5868	10209-10217	NN	denotes	bleeding
T5867	10198-10201	DT	denotes	the
T5866	10195-10197	IN	denotes	of
T5865	10189-10194	NN	denotes	start
T5864	10185-10188	DT	denotes	the
T5863	10181-10184	CC	denotes	and
T5862	10171-10180	NN	denotes	cessation
T5861	10162-10170	NN	denotes	bleeding
T5860	10154-10161	IN	denotes	between
T5859	10149-10153	NN	denotes	time
T5858	10145-10148	DT	denotes	the
T5857	10140-10144	IN	denotes	from
T5856	10127-10130	VBD	denotes	was
T5855	10111-10121	NN	denotes	rebleeding
T5854	10122-10126	NN	denotes	time
T5853	10107-10110	DT	denotes	the
T5852	10105-10107	,	denotes	,
T5851	10090-10096	NN	denotes	saline
T5850	10085-10089	JJ	denotes	same
T5849	10097-10105	NN	denotes	solution
T5848	10081-10084	DT	denotes	the
T5847	10078-10080	IN	denotes	in
T5846	10068-10077	VBG	denotes	remaining
T5845	10063-10067	NN	denotes	tail
T5844	10059-10062	DT	denotes	the
T5843	10131-10139	VBN	denotes	measured
T5842	10054-10058	IN	denotes	With
T5841	10053-10218	sentence	denotes	With the tail remaining in the same saline solution, the rebleeding time was measured from the time between bleeding cessation and the start of the second bleeding.
T5840	10052-10053	.	denotes	.
T5839	10044-10052	NN	denotes	bleeding
T5838	10041-10043	IN	denotes	of
T5837	10031-10040	NN	denotes	cessation
T5836	10028-10030	IN	denotes	to
T5835	10019-10027	VBG	denotes	bleeding
T5834	10016-10018	IN	denotes	of
T5833	10010-10015	NN	denotes	start
T5832	10006-10009	DT	denotes	the
T5831	9998-10005	IN	denotes	between
T5830	9993-9997	NN	denotes	time
T5829	9989-9992	DT	denotes	the
T5828	9986-9988	IN	denotes	as
T5827	9973-9976	VBD	denotes	was
T5826	9977-9985	VBN	denotes	measured
T5825	9968-9972	NN	denotes	time
T5824	9959-9967	NN	denotes	Bleeding
T5823	9958-10053	sentence	denotes	Bleeding time was measured as the time between the start of bleeding to cessation of bleeding.
T5822	9957-9958	.	denotes	.
T5821	9951-9957	NN	denotes	saline
T5820	9947-9950	DT	denotes	the
T5819	9944-9946	IN	denotes	to
T5818	9935-9943	VBD	denotes	returned
T5817	9923-9934	RB	denotes	immediately
T5816	9919-9922	CC	denotes	and
T5815	9909-9918	VBN	denotes	amputated
T5814	9896-9900	NN	denotes	tail
T5813	9893-9895	NN	denotes	mm
T5812	9891-9892	CD	denotes	5
T5811	9901-9908	NN	denotes	segment
T5810	9889-9890	DT	denotes	a
T5809	9885-9888	CC	denotes	and
T5808	9878-9884	NN	denotes	saline
T5807	9874-9877	DT	denotes	the
T5806	9869-9873	IN	denotes	from
T5805	9858-9861	VBD	denotes	was
T5804	9862-9868	VBN	denotes	lifted
T5803	9853-9857	NN	denotes	tail
T5802	9849-9852	DT	denotes	The
T5801	9848-9958	sentence	denotes	The tail was lifted from the saline and a 5 mm tail segment amputated and immediately returned to the saline.
T5800	9847-9848	.	denotes	.
T5799	9837-9842	NN	denotes	water
T5798	9843-9847	NN	denotes	bath
T5797	9835-9836	DT	denotes	a
T5796	9832-9834	IN	denotes	in
T5795	9829-9831	NNS	denotes	°C
T5794	9827-9829	CD	denotes	37
T5793	9824-9826	IN	denotes	at
T5792	9817-9823	NN	denotes	saline
T5791	9814-9816	IN	denotes	of
T5790	9811-9813	NNS	denotes	mL
T5789	9808-9810	CD	denotes	10
T5788	9805-9807	IN	denotes	in
T5787	9801-9804	NNS	denotes	min
T5786	9799-9800	CD	denotes	5
T5785	9795-9798	IN	denotes	for
T5784	9780-9784	NN	denotes	tail
T5783	9776-9779	DT	denotes	the
T5782	9774-9776	,	denotes	,
T5781	9773-9774	-RRB-	denotes	)
T5780	9771-9773	NN	denotes	kg
T5779	9770-9771	SYM	denotes	/
T5777	9764-9766	,	denotes	,
T5776	9762-9764	NN	denotes	kg
T5775	9761-9762	SYM	denotes	/
T5774	9759-9761	NNS	denotes	mg
T5773	9756-9758	CD	denotes	80
T5772	9768-9770	NNS	denotes	mg
T5771	9755-9756	-LRB-	denotes	(
T5770	9745-9746	HYPH	denotes	/
T5769	9746-9754	NN	denotes	xylazine
T5768	9737-9745	NN	denotes	ketamine
T5767	9732-9736	IN	denotes	with
T5766	9785-9794	VBN	denotes	prewarmed
T5765	9714-9718	VBD	denotes	were
T5764	9709-9713	NNS	denotes	mice
T5763	9707-9709	,	denotes	,
T5762	9693-9701	NN	denotes	bleeding
T5761	9688-9692	NN	denotes	tail
T5760	9702-9707	NN	denotes	assay
T5759	9684-9687	DT	denotes	the
T5758	9719-9731	VBN	denotes	anesthetized
T5757	9680-9683	IN	denotes	For
T5756	9679-9848	sentence	denotes	For the tail bleeding assay, mice were anesthetized with ketamine/xylazine (80 mg/kg, 5 mg/kg), the tail prewarmed for 5 min in 10 mL of saline at 37°C in a water bath.
T5755	9663-9673	NN	denotes	rebleeding
T5754	9659-9662	CC	denotes	and
T5753	9674-9679	NN	denotes	assay
T5752	9650-9658	NN	denotes	Bleeding
T5501	9558-9560	DT	denotes	no
T5500	9554-9557	VBD	denotes	was
T5499	9548-9553	EX	denotes	There
T5498	9547-9648	sentence	denotes	There was no difference in body weight among the mice that were tested in the vascular injury model.
T5497	9546-9547	.	denotes	.
T5496	9545-9546	-RRB-	denotes	)
T5495	9534-9539	NN	denotes	model
T5494	9532-9534	,	denotes	,
T5493	9525-9532	NNP	denotes	Systems
T5492	9515-9524	NNP	denotes	Transonic
T5491	9540-9545	NN	denotes	TS420
T5490	9514-9515	-LRB-	denotes	(
T5489	9507-9509	CD	denotes	10
T5488	9510-9513	NN	denotes	sec
T5487	9501-9506	DT	denotes	every
T5486	9488-9491	VBD	denotes	was
T5485	9492-9500	VBN	denotes	recorded
T5484	9483-9487	NN	denotes	flow
T5483	9477-9482	NN	denotes	Blood
T5482	9476-9547	sentence	denotes	Blood flow was recorded every 10 sec (Transonic Systems, model TS420).
T5481	9475-9476	.	denotes	.
T5480	9463-9466	RB	denotes	not
T5479	9459-9462	VBD	denotes	had
T5478	9456-9458	PRP	denotes	it
T5477	9467-9475	VBN	denotes	occluded
T5476	9453-9455	IN	denotes	if
T5475	9449-9452	NNS	denotes	min
T5474	9446-9448	CD	denotes	30
T5473	9443-9445	IN	denotes	at
T5472	9435-9442	VBD	denotes	stopped
T5471	9432-9434	CC	denotes	or
T5470	9419-9423	VBN	denotes	been
T5469	9415-9418	VBD	denotes	had
T5468	9398-9404	JJ	denotes	stable
T5467	9405-9414	NN	denotes	occlusion
T5466	9394-9397	DT	denotes	the
T4815	8307-8311	NNS	denotes	Mice
T4814	8306-8472	sentence	denotes	Mice were fed a standard autoclavable laboratory diet consisting of: 23% protein, 4.5% fat, 6% fiber, (Purina, St. Louis, MO), and tested between 7 and 9 wks-of-age.
T4813	8305-8306	.	denotes	.
T4812	8298-8305	FW	denotes	libitum
T4811	8295-8297	FW	denotes	ad
T4810	8289-8294	NN	denotes	water
T4809	8285-8288	CC	denotes	and
T4808	8280-8284	NN	denotes	food
T4807	8269-8279	VBN	denotes	sterilized
T4806	8260-8268	VBN	denotes	provided
T4805	8255-8259	VBD	denotes	were
T4804	8251-8254	CC	denotes	and
T4803	8249-8251	,	denotes	,
T4802	8239-8243	NN	denotes	dark
T4801	8236-8238	NN	denotes	hr
T4800	8233-8235	CD	denotes	10
T4799	8232-8233	HYPH	denotes	/
T4798	8227-8232	NN	denotes	light
T4797	8224-8226	NN	denotes	hr
T4796	8221-8223	CD	denotes	14
T4795	8244-8249	NN	denotes	cycle
T4794	8219-8220	DT	denotes	a
T4793	8216-8218	IN	denotes	on
T4792	8205-8215	VBN	denotes	maintained
T4791	8203-8205	,	denotes	,
T4790	8189-8197	NN	denotes	isolator
T4789	8198-8203	NNS	denotes	cages
T4788	8178-8188	VBN	denotes	sterilized
T4787	8175-8177	IN	denotes	in
T4786	8163-8167	VBD	denotes	were
T4785	8168-8174	VBN	denotes	housed
T4784	8158-8162	NNS	denotes	Mice
T4783	8157-8306	sentence	denotes	Mice were housed in sterilized isolator cages, maintained on a 14 hr light/10 hr dark cycle, and were provided sterilized food and water ad libitum.
T4782	8156-8157	.	denotes	.
T4781	8155-8156	-RRB-	denotes	)
T4780	8152-8155	NN	denotes	CCF
T4779	8151-8152	-LRB-	denotes	(
T4778	8133-8139	NNP	denotes	Clinic
T4777	8123-8132	NNP	denotes	Cleveland
T4776	8140-8150	NNP	denotes	Foundation
T4775	8119-8122	DT	denotes	the
T4774	8116-8118	IN	denotes	at
T4773	8102-8110	NNP	denotes	Resource
T4772	8091-8101	NNP	denotes	Biological
T4771	8111-8115	NNP	denotes	Unit
T4770	8087-8090	DT	denotes	the
T4769	8084-8086	IN	denotes	in
T4768	8079-8083	VBN	denotes	bred
T4767	8075-8078	CC	denotes	and
T4766	8063-8067	VBD	denotes	were
T4765	8068-8074	VBN	denotes	housed
T4764	8058-8062	NNS	denotes	mice
T4763	8054-8057	DT	denotes	All
T4762	8053-8157	sentence	denotes	All mice were housed and bred in the Biological Resource Unit at the Cleveland Clinic Foundation (CCF).
T4761	8052-8053	.	denotes	.
T4760	8039-8041	POS	denotes	's
T4759	8042-8052	NN	denotes	laboratory
T4758	8033-8039	NNP	denotes	Nadeau
T4757	8029-8032	NNP	denotes	Dr.
T4756	8024-8028	IN	denotes	from
T4755	8007-8011	VBD	denotes	were
T4754	7998-8001	NN	denotes	CSS
T4753	8002-8006	NNS	denotes	mice
T4752	7994-7997	DT	denotes	the
T4751	7991-7993	IN	denotes	of
T4750	8012-8023	VBN	denotes	transferred
T4749	7985-7990	NNS	denotes	pairs
T4748	7976-7984	NN	denotes	Breeding
T4747	7975-8053	sentence	denotes	Breeding pairs of the CSS mice were transferred from Dr. Nadeau's laboratory.
T4746	7974-7975	.	denotes	.
T4745	7973-7974	-RRB-	denotes	]
T4744	7971-7973	CD	denotes	17
T4743	7970-7971	-LRB-	denotes	[
T4742	7960-7963	NN	denotes	ear
T4741	7964-7969	NN	denotes	punch
T4740	7957-7959	DT	denotes	an
T4739	7952-7956	IN	denotes	from
T4738	7948-7951	NN	denotes	age
T4737	7947-7948	HYPH	denotes	-
T4736	7945-7947	IN	denotes	of
T4735	7944-7945	HYPH	denotes	-
T4734	7939-7944	NNS	denotes	weeks
T4733	7936-7937	SYM	denotes	–
T4732	7937-7938	CD	denotes	4
T4731	7935-7936	CD	denotes	3
T4730	7932-7934	IN	denotes	at
T4729	7922-7925	NN	denotes	PCR
T4728	7926-7931	NN	denotes	assay
T4727	7920-7921	DT	denotes	a
T4726	7917-7919	IN	denotes	by
T4725	7901-7905	VBD	denotes	were
T4724	7891-7900	NN	denotes	offspring
T4723	7887-7890	DT	denotes	the
T4722	7884-7886	IN	denotes	of
T4721	7882-7883	-RRB-	denotes	)
T4720	7881-7882	SYM	denotes	-
T4719	7880-7881	HYPH	denotes	/
T4718	7879-7880	SYM	denotes	-
T4717	7876-7879	NN	denotes	Plg
T4716	7874-7876	,	denotes	,
T4715	7873-7874	SYM	denotes	-
T4714	7872-7873	HYPH	denotes	/
T4713	7871-7872	SYM	denotes	+
T4712	7868-7871	NN	denotes	Plg
T4711	7866-7868	,	denotes	,
T4710	7865-7866	SYM	denotes	+
T4709	7864-7865	HYPH	denotes	/
T4708	7863-7864	SYM	denotes	+
T4707	7860-7863	NN	denotes	Plg
T4706	7859-7860	-LRB-	denotes	(
T4705	7906-7916	VBN	denotes	determined
T4704	7849-7858	NNS	denotes	Genotypes
T4703	7848-7975	sentence	denotes	Genotypes (Plg+/+, Plg+/-, Plg-/-) of the offspring were determined by a PCR assay at 3–4 weeks-of-age from an ear punch [17].
T4702	7847-7848	.	denotes	.
T4701	7839-7847	NN	denotes	breeding
T4700	7835-7838	IN	denotes	for
T4699	7825-7829	VBD	denotes	were
T4698	7830-7834	VBN	denotes	used
T4697	7806-7818	JJ	denotes	heterozygous
T4696	7819-7824	NNS	denotes	pairs
T4695	7802-7805	NN	denotes	Plg
T4694	7798-7801	CC	denotes	and
T4693	7793-7797	RB	denotes	well
T4692	7779-7782	RB	denotes	not
T4691	7776-7778	VBP	denotes	do
T4690	7783-7792	VB	denotes	reproduce
T4689	7769-7770	SYM	denotes	-
T4688	7768-7769	HYPH	denotes	/
T4687	7767-7768	SYM	denotes	-
T4686	7764-7767	NN	denotes	Plg
T4685	7771-7775	NNS	denotes	mice
T4684	7760-7763	DT	denotes	The
T4683	7759-7848	sentence	denotes	The Plg-/- mice do not reproduce well and Plg heterozygous pairs were used for breeding.
T4682	7758-7759	.	denotes	.
T4681	7754-7758	NNS	denotes	mice
T4680	7751-7753	NN	denotes	B6
T4679	7746-7750	IN	denotes	with
T4678	7734-7745	NNS	denotes	generations
T4677	7728-7733	CD	denotes	eight
T4676	7724-7727	IN	denotes	for
T4675	7711-7712	-RRB-	denotes	)
T4674	7708-7711	CD	denotes	129
T4673	7707-7708	HYPH	denotes	:
T4672	7705-7707	NN	denotes	B6
T4671	7704-7705	-LRB-	denotes	(
T4670	7698-7703	JJ	denotes	mixed
T4669	7689-7697	JJ	denotes	original
T4668	7713-7723	NN	denotes	background
T4667	7685-7688	DT	denotes	the
T4666	7680-7684	IN	denotes	from
T4665	7675-7679	NNS	denotes	mice
T4664	7666-7674	VBG	denotes	crossing
T4663	7663-7665	IN	denotes	by
T4662	7653-7662	VBN	denotes	generated
T4661	7651-7653	,	denotes	,
T4660	7638-7640	NN	denotes	B6
T4659	7641-7651	NN	denotes	background
T4658	7634-7637	DT	denotes	the
T4657	7631-7633	IN	denotes	in
T4656	7620-7630	VBN	denotes	maintained
T4655	7616-7619	CC	denotes	and
T4654	7614-7615	-RRB-	denotes	]
T4653	7612-7614	CD	denotes	16
T4652	7611-7612	-LRB-	denotes	[
T4651	7590-7600	RB	denotes	previously
T4650	7601-7610	VBN	denotes	described
T4649	7587-7589	IN	denotes	as
T4648	7572-7576	VBD	denotes	were
T4647	7577-7586	VBN	denotes	generated
T4646	7565-7566	SYM	denotes	-
T4645	7564-7565	HYPH	denotes	/
T4644	7563-7564	SYM	denotes	-
T4643	7560-7563	NN	denotes	Plg
T4642	7567-7571	NNS	denotes	mice
T4641	7556-7559	DT	denotes	The
T4640	7555-7759	sentence	denotes	The Plg-/- mice were generated as previously described [16] and maintained in the B6 background, generated by crossing mice from the original mixed (B6:129) background for eight generations with B6 mice.
T4639	7554-7555	.	denotes	.
T4638	7551-7554	NN	denotes	age
T4637	7550-7551	HYPH	denotes	-
T4636	7548-7550	IN	denotes	of
T4635	7547-7548	HYPH	denotes	-
T4634	7544-7547	NNS	denotes	wks
T4633	7542-7543	CD	denotes	6
T4632	7539-7541	IN	denotes	at
T4631	7537-7538	-RRB-	denotes	)
T4630	7532-7537	NNP	denotes	Maine
T4629	7530-7532	,	denotes	,
T4628	7524-7530	NNP	denotes	Harbor
T4627	7520-7523	NNP	denotes	Bar
T4626	7519-7520	-LRB-	denotes	(
T4625	7508-7518	NNP	denotes	Laboratory
T4624	7500-7507	NNP	denotes	Jackson
T4623	7495-7499	IN	denotes	from
T4622	7481-7485	VBD	denotes	were
T4621	7467-7469	NN	denotes	B6
T4620	7470-7480	NN	denotes	background
T4619	7465-7466	DT	denotes	a
T4618	7462-7464	IN	denotes	in
T4617	7455-7456	-RRB-	denotes	]
T4616	7453-7455	CD	denotes	15
T4615	7452-7453	-LRB-	denotes	[
T4614	7450-7451	-RRB-	denotes	)
T4613	7444-7450	CD	denotes	002507
T4612	7443-7444	NN	denotes	#
T4611	7442-7443	-LRB-	denotes	(
T4610	7440-7441	-RRB-	denotes	)
T4609	7439-7440	SYM	denotes	-
T4608	7438-7439	HYPH	denotes	/
T4607	7437-7438	SYM	denotes	-
T4606	7436-7437	CD	denotes	1
T4605	7435-7436	HYPH	denotes	-
T4604	7457-7461	NNS	denotes	mice
T4603	7432-7435	NN	denotes	PAI
T4602	7431-7432	-LRB-	denotes	(
T4601	7416-7425	JJ	denotes	deficient
T4600	7396-7405	NN	denotes	activator
T4595	7378-7389	NN	denotes	plasminogen
T4594	7426-7430	NNS	denotes	mice
T4593	7368-7369	HYPH	denotes	-
T4592	7369-7377	VBN	denotes	targeted
T4591	7364-7368	NN	denotes	gene
T4590	7360-7363	CC	denotes	and
T4589	7358-7359	-RRB-	denotes	)
T4588	7352-7358	CD	denotes	000646
T4587	7351-7352	NN	denotes	#
T4586	7350-7351	-LRB-	denotes	(
T4585	7347-7348	HYPH	denotes	/
T4584	7348-7349	NN	denotes	J
T4583	7346-7347	NN	denotes	A
T4582	7344-7346	,	denotes	,
T4581	7343-7344	-RRB-	denotes	)
T4580	7337-7343	CD	denotes	000632
T4579	7336-7337	NN	denotes	#
T4578	7335-7336	-LRB-	denotes	(
T4577	7329-7334	NN	denotes	Lepob
T4576	7327-7329	,	denotes	,
T4575	7326-7327	-RRB-	denotes	)
T4574	7320-7326	CD	denotes	000664
T4573	7319-7320	NN	denotes	#
T4572	7318-7319	-LRB-	denotes	(
T4571	7315-7317	NN	denotes	B6
T4570	7313-7315	,	denotes	,
T4569	7486-7494	VBN	denotes	obtained
T4568	7299-7305	JJ	denotes	inbred
T4567	7306-7313	NNS	denotes	strains
T4566	7295-7298	DT	denotes	The
T4565	7294-7555	sentence	denotes	The inbred strains, B6 (#000664), Lepob (#000632), A/J (#000646) and gene-targeted plasminogen (Plg) activator inhibitor deficient mice (PAI-1-/-) (#002507) [15] mice in a B6 background were obtained from Jackson Laboratory (Bar Harbor, Maine) at 6 wks-of-age.
T4564	7290-7294	NNS	denotes	Mice
T4882	8621-8622	.	denotes	.
T4881	8618-8621	NNP	denotes	CCF
T4880	8615-8617	IN	denotes	at
T4879	8596-8604	NNP	denotes	Advisory
T4878	8587-8595	NNP	denotes	Research
T4877	8583-8586	CC	denotes	and
T4876	8578-8582	NNP	denotes	Care
T4875	8571-8577	NNP	denotes	Animal
T4874	8557-8570	NNP	denotes	Institutional
T4873	8605-8614	NNP	denotes	Committee
T4872	8553-8556	DT	denotes	the
T4871	8550-8552	IN	denotes	by
T4870	8541-8549	VBN	denotes	approved
T4869	8532-8540	NN	denotes	protocol
T4868	8530-8531	DT	denotes	a
T4867	8525-8529	IN	denotes	with
T4866	8514-8524	NN	denotes	accordance
T4865	8511-8513	IN	denotes	in
T4864	8496-8500	VBD	denotes	were
T4863	8501-8510	VBN	denotes	performed
T4862	8477-8483	NN	denotes	animal
T4861	8484-8495	NNS	denotes	experiments
T4860	8473-8476	DT	denotes	All
T4859	8472-8622	sentence	denotes	All animal experiments were performed in accordance with a protocol approved by the Institutional Animal Care and Research Advisory Committee at CCF.
T4858	8471-8472	.	denotes	.
T4857	8468-8471	NN	denotes	age
T4856	8467-8468	HYPH	denotes	-
T4855	8465-8467	IN	denotes	of
T4854	8464-8465	HYPH	denotes	-
T4853	8459-8460	CD	denotes	9
T4852	8455-8458	CC	denotes	and
T4851	8461-8464	NNS	denotes	wks
T4850	8453-8454	CD	denotes	7
T4849	8445-8452	IN	denotes	between
T4848	8438-8444	VBN	denotes	tested
T4847	8434-8437	CC	denotes	and
T4846	8432-8434	,	denotes	,
T4845	8431-8432	-RRB-	denotes	)
T4844	8429-8431	NNP	denotes	MO
T4843	8427-8429	,	denotes	,
T4842	8422-8427	NNP	denotes	Louis
T4841	8418-8421	NNP	denotes	St.
T4840	8416-8418	,	denotes	,
T4839	8410-8416	NNP	denotes	Purina
T4838	8409-8410	-LRB-	denotes	(
T4837	8407-8409	,	denotes	,
T4836	8402-8407	NN	denotes	fiber
T4835	8400-8401	NN	denotes	%
T4834	8399-8400	CD	denotes	6
T4833	8397-8399	,	denotes	,
T4832	8394-8397	NN	denotes	fat
T4831	8392-8393	NN	denotes	%
T4830	8389-8392	CD	denotes	4.5
T4829	8387-8389	,	denotes	,
T4828	8380-8387	NN	denotes	protein
T4827	8378-8379	NN	denotes	%
T4826	8376-8378	CD	denotes	23
T4825	8374-8376	:	denotes	:
T4824	8372-8374	IN	denotes	of
T4823	8361-8371	VBG	denotes	consisting
T4822	8345-8355	NN	denotes	laboratory
T4821	8332-8344	JJ	denotes	autoclavable
T4820	8323-8331	JJ	denotes	standard
T4819	8356-8360	NN	denotes	diet
T4818	8321-8322	DT	denotes	a
T4817	8312-8316	VBD	denotes	were
T4816	8317-8320	VBN	denotes	fed
T4599	7394-7395	-RRB-	denotes	)
T4598	7391-7394	NN	denotes	Plg
T4597	7390-7391	-LRB-	denotes	(
T4596	7406-7415	NN	denotes	inhibitor
T3927	7268-7278	NN	denotes	thrombosis
T3926	7264-7267	CC	denotes	and
T3925	7252-7263	NN	denotes	haemostasis
T3924	7239-7251	JJ	denotes	pathological
T3923	7236-7238	IN	denotes	to
T3922	7221-7235	NN	denotes	susceptibility
T3921	7218-7220	IN	denotes	of
T3920	7197-7204	JJ	denotes	genetic
T3919	7205-7217	NNS	denotes	determinants
T3918	7185-7196	JJ	denotes	independent
T3917	7176-7184	VB	denotes	identify
T3916	7173-7175	TO	denotes	to
T3915	7164-7172	JJ	denotes	possible
T3914	7154-7160	MD	denotes	should
T3913	7151-7153	PRP	denotes	it
T3912	7149-7151	,	denotes	,
T3911	7161-7163	VB	denotes	be
T3910	7145-7149	RB	denotes	Thus
T3909	7144-7279	sentence	denotes	Thus, it should be possible to identify independent genetic determinants of susceptibility to pathological haemostasis and thrombosis.
T3908	7143-7144	.	denotes	.
T3907	7137-7138	HYPH	denotes	/
T3906	7138-7139	NN	denotes	J
T3905	7136-7137	NN	denotes	A
T3904	7140-7143	NN	denotes	QTL
T3903	7132-7135	DT	denotes	the
T3902	7126-7131	IN	denotes	among
T3901	7104-7116	NNS	denotes	interactions
T3900	7117-7125	VBD	denotes	occurred
T3899	7099-7103	IN	denotes	that
T3898	7089-7098	VBD	denotes	suggested
T3897	7085-7088	CC	denotes	and
T3896	7083-7085	,	denotes	,
T3895	7070-7072	NN	denotes	B6
T3894	7073-7083	NN	denotes	background
T3893	7066-7069	DT	denotes	the
T3892	7063-7065	IN	denotes	in
T3891	7050-7053	VBD	denotes	was
T3890	7048-7050	,	denotes	,
T3889	7039-7048	NN	denotes	occlusion
T3888	7030-7038	JJ	denotes	arterial
T3887	7026-7029	CC	denotes	and
T3886	7021-7025	NN	denotes	time
T3885	7010-7020	NN	denotes	rebleeding
T3884	7008-7010	,	denotes	,
T3883	6995-6996	HYPH	denotes	/
T3882	6996-6997	NN	denotes	J
T3881	6994-6995	NN	denotes	A
T3880	6998-7008	NNS	denotes	phenotypes
T3879	6990-6993	DT	denotes	the
T3878	6987-6989	IN	denotes	of
T3877	6976-6986	NN	denotes	expression
T3876	6974-6976	,	denotes	,
T3875	6971-6974	NN	denotes	CSS
T3874	6967-6970	DT	denotes	the
T3873	6964-6966	IN	denotes	in
T3872	6962-6964	,	denotes	,
T3871	6954-6962	NN	denotes	addition
T3870	7054-7062	VBN	denotes	modified
T3869	6951-6953	IN	denotes	In
T3868	6950-7144	sentence	denotes	In addition, in the CSS, expression of the A/J phenotypes, rebleeding time and arterial occlusion, was modified in the B6 background, and suggested that interactions occurred among the A/J QTL.
T3867	6949-6950	.	denotes	.
T3866	6938-6949	NN	denotes	aggregation
T3865	6929-6937	NN	denotes	platelet
T3864	6926-6928	CC	denotes	or
T3863	6914-6925	NN	denotes	coagulation
T3862	6911-6913	IN	denotes	to
T3861	6901-6910	JJ	denotes	unrelated
T3734	6328-6332	DT	denotes	this
T3733	6325-6327	IN	denotes	of
T3732	6375-6383	VBN	denotes	reported
T3731	6317-6324	NNS	denotes	studies
T3730	6309-6316	JJ	denotes	Several
T3729	6308-6565	sentence	denotes	Several studies of this CSS panel, B6 Chr1-19, X, YA/J, have been reported for behavior [12], weight gain [13], sterols [13], and plasma amino acids levels [13,14], and have identified many more QTL than studies of the same traits using a genome-wide scan.
T3728	6307-6308	.	denotes	.
T3727	6304-6307	NN	denotes	QTL
T3726	6301-6303	IN	denotes	of
T3725	6292-6293	HYPH	denotes	-
T3724	6288-6292	RB	denotes	fine
T3723	6293-6300	VBG	denotes	mapping
T3722	6284-6287	DT	denotes	the
T3721	6271-6274	NN	denotes	CSS
T3720	6267-6270	DT	denotes	the
T3719	6262-6266	IN	denotes	with
T3718	6254-6261	NNS	denotes	screens
T3717	6246-6253	JJ	denotes	initial
T3716	6244-6246	,	denotes	,
T3715	6236-6244	NN	denotes	addition
T3714	6275-6283	VBP	denotes	simplify
T3713	6233-6235	IN	denotes	In
T3712	6232-6308	sentence	denotes	In addition, initial screens with the CSS simplify the fine-mapping of QTL.
T3711	6231-6232	.	denotes	.
T3710	6228-6231	NN	denotes	QTL
T3709	6222-6227	JJ	denotes	other
T3708	6219-6221	IN	denotes	of
T3707	6210-6218	NN	denotes	presence
T3706	6206-6209	DT	denotes	the
T3705	6203-6205	IN	denotes	in
T3704	6199-6202	NNS	denotes	QTL
T3703	6196-6198	IN	denotes	of
T3702	6186-6195	NN	denotes	detection
T3701	6182-6185	IN	denotes	for
T3700	6174-6181	NN	denotes	ability
T3699	6170-6173	DT	denotes	the
T3698	6167-6169	VBZ	denotes	is
T3697	6157-6166	NN	denotes	advantage
T3696	6149-6156	DT	denotes	Another
T3695	6148-6232	sentence	denotes	Another advantage is the ability for detection of QTL in the presence of other QTL.
T3694	6147-6148	.	denotes	.
T3693	6137-6138	HYPH	denotes	-
T3692	6138-6142	JJ	denotes	wide
T3691	6131-6137	NN	denotes	genome
T3690	6143-6147	NN	denotes	scan
T3689	6129-6130	DT	denotes	a
T3688	6124-6128	VBZ	denotes	does
T3687	6119-6123	IN	denotes	than
T3686	6115-6118	NN	denotes	QTL
T3685	6111-6114	DT	denotes	the
T3684	6101-6110	VB	denotes	determine
T3683	6098-6100	TO	denotes	to
T3682	6093-6097	NNS	denotes	mice
T3681	6087-6092	JJR	denotes	fewer
T3680	6072-6077	NN	denotes	panel
T3679	6067-6071	DT	denotes	this
T3678	6064-6066	IN	denotes	of
T3677	6078-6086	VBZ	denotes	requires
T3676	6060-6063	NN	denotes	Use
T3675	6059-6148	sentence	denotes	Use of this panel requires fewer mice to determine the QTL than does a genome-wide scan.
T3674	6058-6059	.	denotes	.
T3673	6048-6058	NN	denotes	chromosome
T3672	6043-6047	DT	denotes	this
T3671	6040-6042	IN	denotes	on
T3670	6028-6031	NN	denotes	QTL
T3669	6018-6023	RBS	denotes	least
T3668	6024-6027	CD	denotes	one
T3667	6015-6017	RB	denotes	at
T3666	6032-6039	VBZ	denotes	resides
T3665	6010-6014	IN	denotes	that
T3664	6002-6009	VBZ	denotes	implies
T3663	5998-6001	CC	denotes	and
T3662	5989-5993	JJR	denotes	more
T3661	5986-5988	CC	denotes	or
T3660	5994-5997	NN	denotes	CSS
T3659	5982-5985	CD	denotes	one
T3658	5979-5981	IN	denotes	in
T3657	5973-5978	NN	denotes	trait
T3656	5971-5972	DT	denotes	a
T3655	5968-5970	IN	denotes	of
T3654	5953-5967	NN	denotes	identification
T3653	5949-5952	DT	denotes	the
T3652	5942-5948	VBZ	denotes	allows
T3651	5937-5941	DT	denotes	This
T3650	5936-6059	sentence	denotes	This allows the identification of a trait in one or more CSS and implies that at least one QTL resides on this chromosome.
T3649	5935-5936	.	denotes	.
T3648	5922-5924	NN	denotes	B6
T3647	5925-5935	NN	denotes	background
T3646	5920-5921	DT	denotes	a
T3645	5917-5919	IN	denotes	in
T3644	5912-5916	NNS	denotes	mice
T3643	5909-5910	HYPH	denotes	/
T3642	5910-5911	NN	denotes	J
T3641	5908-5909	NN	denotes	A
T3640	5903-5907	IN	denotes	from
T3639	5892-5902	NN	denotes	chromosome
T3638	5888-5891	CD	denotes	one
T3637	5883-5887	VBP	denotes	have
T3636	5875-5882	NNS	denotes	strains
T3635	5869-5874	DT	denotes	These
T3634	5868-5936	sentence	denotes	These strains have one chromosome from A/J mice in a B6 background.
T3633	5867-5868	.	denotes	.
T3632	5857-5867	NN	denotes	chromosome
T3631	5854-5855	HYPH	denotes	/
T3630	5853-5854	NN	denotes	A
T3629	5842-5852	JJ	denotes	individual
T3628	5855-5856	NN	denotes	J
T3627	5838-5841	DT	denotes	the
T3626	5834-5837	CC	denotes	and
T3625	5832-5833	-RRB-	denotes	)
T3624	5829-5830	-LRB-	denotes	(
T3623	5818-5828	NN	denotes	background
T3622	5830-5832	NN	denotes	B6
T3621	5814-5817	DT	denotes	the
T3620	5811-5813	IN	denotes	in
T3619	5798-5810	NN	denotes	homozygosity
T3618	5789-5797	VB	denotes	identify
T3617	5786-5788	TO	denotes	to
T3616	5776-5780	VBD	denotes	were
T3860	6899-6901	,	denotes	,
T3859	6875-6888	JJ	denotes	prothrombotic
T3858	6889-6899	NNS	denotes	phenotypes
T3857	6867-6874	JJ	denotes	diverse
T3856	6860-6862	,	denotes	,
T3855	6853-6854	HYPH	denotes	/
T3854	6854-6855	NN	denotes	J
T3853	6852-6853	NN	denotes	A
T3852	6848-6851	CC	denotes	and
T3851	6856-6860	NNS	denotes	mice
T3850	6845-6847	NN	denotes	B6
T3849	6843-6845	,	denotes	,
T3848	6829-6835	JJ	denotes	inbred
T3847	6825-6828	CD	denotes	two
T3846	6836-6843	NNS	denotes	strains
T3845	6821-6824	DT	denotes	the
T3844	6862-6866	VBP	denotes	have
T3843	6816-6820	IN	denotes	that
T3842	6801-6806	NN	denotes	study
T3841	6796-6800	DT	denotes	this
T3840	6793-6795	IN	denotes	of
T3839	6807-6815	VBP	denotes	indicate
T3838	6785-6792	NNS	denotes	results
T3837	6781-6784	DT	denotes	The
T3836	6780-6950	sentence	denotes	The results of this study indicate that the two inbred strains, B6 and A/J mice, have diverse prothrombotic phenotypes, unrelated to coagulation or platelet aggregation.
T3835	6779-6780	.	denotes	.
T3834	6767-6779	NN	denotes	fibrinolysis
T3833	6763-6766	CC	denotes	and
T3832	6751-6762	NN	denotes	coagulation
T3831	6748-6750	IN	denotes	of
T3830	6739-6747	NNS	denotes	measures
T3829	6735-6738	CC	denotes	and
T3828	6733-6735	,	denotes	,
T3827	6728-6733	NN	denotes	assay
T3826	6719-6727	NN	denotes	bleeding
T3825	6714-6718	NN	denotes	tail
T3824	6712-6714	,	denotes	,
T3823	6700-6706	NN	denotes	injury
T3822	6691-6699	JJ	denotes	vascular
T3821	6682-6690	NN	denotes	chloride
T3820	6675-6681	JJ	denotes	ferric
T3819	6707-6712	NN	denotes	model
T3818	6673-6674	DT	denotes	a
T3817	6663-6672	VBG	denotes	utilizing
T3816	6661-6663	,	denotes	,
T3815	6657-6661	NN	denotes	risk
T3814	6643-6656	JJ	denotes	prothrombotic
T3813	6639-6642	IN	denotes	for
T3812	6634-6638	NNS	denotes	mice
T3811	6631-6633	IN	denotes	of
T3810	6616-6622	JJ	denotes	inbred
T3809	6612-6615	CD	denotes	two
T3808	6623-6630	NNS	denotes	strains
T3807	6608-6611	DT	denotes	the
T3806	6599-6607	VB	denotes	evaluate
T3805	6596-6598	TO	denotes	to
T3804	6586-6591	NN	denotes	study
T3803	6581-6585	DT	denotes	this
T3802	6578-6580	IN	denotes	of
T3801	6592-6595	VBD	denotes	was
T3800	6570-6577	NN	denotes	purpose
T3799	6566-6569	DT	denotes	The
T3798	6565-6780	sentence	denotes	The purpose of this study was to evaluate the two inbred strains of mice for prothrombotic risk, utilizing a ferric chloride vascular injury model, tail bleeding assay, and measures of coagulation and fibrinolysis.
T3797	6564-6565	.	denotes	.
T3796	6554-6555	HYPH	denotes	-
T3795	6555-6559	JJ	denotes	wide
T3794	6548-6554	NN	denotes	genome
T3793	6560-6564	NN	denotes	scan
T3792	6546-6547	DT	denotes	a
T3791	6540-6545	VBG	denotes	using
T3790	6528-6532	JJ	denotes	same
T3789	6533-6539	NNS	denotes	traits
T3788	6524-6527	DT	denotes	the
T3787	6521-6523	IN	denotes	of
T3786	6513-6520	NNS	denotes	studies
T3785	6508-6512	IN	denotes	than
T3784	6504-6507	NN	denotes	QTL
T3783	6499-6503	JJR	denotes	more
T3782	6494-6498	JJ	denotes	many
T3781	6483-6493	VBN	denotes	identified
T3780	6478-6482	VBP	denotes	have
T3779	6474-6477	CC	denotes	and
T3778	6472-6474	,	denotes	,
T3777	6471-6472	-RRB-	denotes	]
T3776	6468-6469	,	denotes	,
T3775	6466-6468	CD	denotes	13
T3774	6469-6471	CD	denotes	14
T3773	6465-6466	-LRB-	denotes	[
T3772	6452-6457	NNS	denotes	acids
T3771	6446-6451	NN	denotes	amino
T3770	6458-6464	NNS	denotes	levels
T3769	6439-6445	NN	denotes	plasma
T3768	6435-6438	CC	denotes	and
T3767	6433-6435	,	denotes	,
T3766	6432-6433	-RRB-	denotes	]
T3765	6430-6432	CD	denotes	13
T3764	6429-6430	-LRB-	denotes	[
T3763	6421-6428	NNS	denotes	sterols
T3762	6419-6421	,	denotes	,
T3761	6418-6419	-RRB-	denotes	]
T3760	6416-6418	CD	denotes	13
T3759	6415-6416	-LRB-	denotes	[
T3758	6410-6414	NN	denotes	gain
T3757	6403-6409	NN	denotes	weight
T3756	6401-6403	,	denotes	,
T3755	6400-6401	-RRB-	denotes	]
T3754	6398-6400	CD	denotes	12
T3753	6397-6398	-LRB-	denotes	[
T3752	6388-6396	NN	denotes	behavior
T3751	6384-6387	IN	denotes	for
T3750	6370-6374	VBN	denotes	been
T3749	6365-6369	VBP	denotes	have
T3748	6363-6365	,	denotes	,
T3747	6361-6362	HYPH	denotes	/
T3746	6362-6363	NN	denotes	J
T3745	6359-6361	NN	denotes	YA
T3744	6357-6359	,	denotes	,
T3743	6356-6357	NN	denotes	X
T3742	6354-6356	,	denotes	,
T3741	6351-6352	HYPH	denotes	-
T3740	6347-6351	NN	denotes	Chr1
T3739	6352-6354	NN	denotes	19
T3738	6344-6346	NN	denotes	B6
T3737	6342-6344	,	denotes	,
T3736	6333-6336	NN	denotes	CSS
T3735	6337-6342	NN	denotes	panel
T6631	11404-11405	.	denotes	.
T6630	11403-11404	-RRB-	denotes	)
T6629	11397-11403	NNP	denotes	France
T6628	11395-11397	,	denotes	,
T6627	11382-11388	NNP	denotes	Hyphen
T6626	11389-11395	NNP	denotes	BioMed
T6625	11381-11382	-LRB-	denotes	(
T6624	11370-11380	NN	denotes	fibrinogen
T6623	11364-11369	NN	denotes	mouse
T6622	11354-11363	VBP	denotes	recognize
T6621	11349-11353	WDT	denotes	that
T6620	11338-11348	NNS	denotes	antibodies
T6619	11333-11337	IN	denotes	with
T6618	11321-11326	NN	denotes	ELISA
T6617	11327-11332	NN	denotes	assay
T6861	11684-11689	NNS	denotes	sites
T6860	11681-11682	SYM	denotes	–
T6859	11682-11683	CD	denotes	3
T6858	11680-11681	CD	denotes	2
T6857	11675-11679	IN	denotes	from
T6856	11666-11674	NNS	denotes	sections
T6855	11661-11665	CD	denotes	four
T6854	11659-11661	,	denotes	,
T6853	11646-11650	NN	denotes	tail
T6852	11651-11659	NNS	denotes	sections
T6851	11642-11645	DT	denotes	the
T6850	11639-11641	IN	denotes	in
T6849	11634-11638	NN	denotes	area
T6848	11625-11633	NN	denotes	collagen
T6847	11622-11624	IN	denotes	of
T6846	11613-11621	NN	denotes	analysis
T6845	11600-11612	JJ	denotes	quantitative
T6844	11695-11703	VBN	denotes	measured
T6843	11596-11599	IN	denotes	For
T6842	11595-11773	sentence	denotes	For quantitative analysis of collagen area in the tail sections, four sections from 2–3 sites were measured using computer assisted image analysis (Image-Pro Plus, Cybernetics).
T6841	11594-11595	.	denotes	.
T6840	11593-11594	-RRB-	denotes	)
T6839	11576-11581	NNP	denotes	Sigma
T6838	11574-11576	,	denotes	,
T6837	11572-11574	CD	denotes	15
T6836	11569-11571	NN	denotes	HT
T6835	11582-11593	NNP	denotes	Diagnostics
T6834	11568-11569	-LRB-	denotes	(
T6833	11555-11557	POS	denotes	's
T6832	11558-11567	NN	denotes	Trichrome
T6831	11549-11555	NNP	denotes	Masson
T6830	11544-11548	IN	denotes	with
T6829	11536-11543	VBD	denotes	stained
T6828	11532-11535	CC	denotes	and
T6827	11522-11531	NN	denotes	thickness
T6826	11519-11521	NNS	denotes	μm
T6825	11517-11518	CD	denotes	5
T6824	11514-11516	IN	denotes	at
T6906	11933-11934	.	denotes	.
T6905	11928-11933	NN	denotes	mouse
T6904	11923-11927	DT	denotes	each
T6903	11919-11922	IN	denotes	for
T6902	11910-11918	VBN	denotes	averaged
T6901	11906-11909	CC	denotes	and
T6900	11892-11896	VBD	denotes	were
T6899	11886-11891	RB	denotes	apart
T6898	11883-11885	NNS	denotes	μm
T6897	11879-11882	CD	denotes	100
T6896	11865-11878	RB	denotes	approximately
T6895	11859-11864	NNS	denotes	sites
T6894	11849-11858	JJ	denotes	different
T6893	11844-11848	IN	denotes	from
T6892	11835-11843	NNS	denotes	sections
T6891	11832-11833	SYM	denotes	–
T6890	11833-11834	CD	denotes	4
T6889	11831-11832	CD	denotes	3
T6888	11829-11831	,	denotes	,
T6887	11816-11823	NN	denotes	carotid
T6886	11808-11815	JJ	denotes	injured
T6885	11824-11829	NN	denotes	lumen
T6884	11804-11807	DT	denotes	the
T6883	11801-11803	IN	denotes	of
T6882	11782-11786	NN	denotes	area
T6881	11787-11800	NN	denotes	determination
T6880	11778-11781	DT	denotes	the
T6879	11897-11905	VBN	denotes	analyzed
T6878	11774-11777	IN	denotes	For
T6877	11773-11934	sentence	denotes	For the area determination of the injured carotid lumen, 3–4 sections from different sites approximately 100 μm apart were analyzed and averaged for each mouse.
T6876	11772-11773	.	denotes	.
T6875	11771-11772	-RRB-	denotes	)
T6874	11758-11760	,	denotes	,
T6873	11750-11753	NNP	denotes	Pro
T6872	11749-11750	HYPH	denotes	-
T6871	11754-11758	NNP	denotes	Plus
T6870	11744-11749	NNP	denotes	Image
T6869	11760-11771	NNP	denotes	Cybernetics
T6868	11743-11744	-LRB-	denotes	(
T6867	11728-11733	NN	denotes	image
T6866	11734-11742	NN	denotes	analysis
T6865	11719-11727	VBN	denotes	assisted
T6864	11710-11718	NN	denotes	computer
T6863	11704-11709	VBG	denotes	using
T6862	11690-11694	VBD	denotes	were
T7172	11976-11979	NN	denotes	SEM
T7171	11969-11973	NN	denotes	mean
T7170	11966-11968	IN	denotes	as
T7169	11952-11955	VBP	denotes	are
T7168	11956-11965	VBN	denotes	presented
T7167	11947-11951	NNS	denotes	Data
T7166	11946-11980	sentence	denotes	Data are presented as mean ± SEM.
T7165	11936-11946	NN	denotes	Statistics
T7300	12540-12541	.	denotes	.
T7299	12539-12540	-RRB-	denotes	]
T7298	12537-12539	CD	denotes	13
T7297	12536-12537	-LRB-	denotes	[
T7296	12528-12535	NN	denotes	testing
T7295	12512-12527	NN	denotes	multihypothesis
T7294	12508-12511	IN	denotes	for
T7293	12500-12507	VB	denotes	account
T7292	12497-12499	TO	denotes	to
T7291	12475-12485	NNP	denotes	Bonferroni
T7290	12486-12496	NN	denotes	correction
T7289	12473-12474	DT	denotes	a
T7288	12468-12472	IN	denotes	with
T7287	12455-12456	-RRB-	denotes	)
T7286	12448-12455	NNS	denotes	legends
T7285	12441-12447	NN	denotes	figure
T7284	12437-12440	VB	denotes	see
T7283	12436-12437	-LRB-	denotes	(
T7282	12428-12429	HYPH	denotes	-
T7281	12427-12428	NN	denotes	P
T7280	12415-12426	JJ	denotes	significant
T7279	12429-12435	NNS	denotes	values
T7278	12411-12414	DT	denotes	the
T8205	13218-13219	-RRB-	denotes	)
T8204	13215-13216	SYM	denotes	=
T8203	13217-13218	CD	denotes	3
T8202	13213-13214	NN	denotes	n
T8419	14061-14062	.	denotes	.
T9878	17238-17239	.	denotes	.
T10236	17348-17360	VBG	denotes	contributing
T10235	17331-17342	NN	denotes	coagulation
T10234	17328-17330	IN	denotes	in
T10233	17316-17327	NNS	denotes	differences
T10232	17343-17347	VBD	denotes	were
T10231	17313-17315	IN	denotes	if
T10230	17485-17493	VBN	denotes	measured
T10229	17303-17312	VB	denotes	determine
T10228	17300-17302	TO	denotes	To
T10227	17299-17494	sentence	denotes	To determine if differences in coagulation were contributing factors to the bleeding and rebleeding results, prothrombin time (PT) and activated partial thromboplastin time (aPTT) were measured.
T10226	17292-17293	HYPH	denotes	/
T10225	17293-17294	NN	denotes	J
T10224	17291-17292	NN	denotes	A
T10223	17287-17290	CC	denotes	and
T10222	17295-17299	NNS	denotes	mice
T10221	17284-17286	NN	denotes	B6
T10220	17276-17283	IN	denotes	between
T10219	17264-17275	NN	denotes	coagulation
T10218	17258-17263	NN	denotes	blood
T10217	17255-17257	IN	denotes	in
T10216	17244-17254	NN	denotes	difference
T10215	17241-17243	DT	denotes	No
T11221	19793-19796	CD	denotes	two
T11220	19803-19810	NNS	denotes	strains
T11219	19789-19792	DT	denotes	the
T11218	19786-19788	IN	denotes	in
T11217	19782-19785	NN	denotes	Plg
T11216	19779-19781	IN	denotes	of
T11215	19769-19778	NN	denotes	structure
T11214	19765-19768	DT	denotes	the
T11213	19762-19764	IN	denotes	in
T11212	19747-19753	JJ	denotes	marked
T11211	19754-19761	NNS	denotes	changes
T11210	19744-19746	DT	denotes	no
T11209	19733-19743	VBG	denotes	suggesting
T11208	19731-19733	,	denotes	,
T11207	19719-19722	VBD	denotes	was
T11206	19703-19718	NN	denotes	electrophoresis
T11205	19697-19702	IN	denotes	after
T11204	19687-19696	NN	denotes	migration
T11203	19684-19686	IN	denotes	in
T11202	19723-19731	VBN	denotes	observed
T11201	19673-19683	NN	denotes	difference
T11200	19670-19672	DT	denotes	no
T11199	19666-19669	CC	denotes	and
T11198	19658-19665	NNS	denotes	methods
T11197	19654-19657	CD	denotes	two
T11196	19651-19653	IN	denotes	by
T11195	19640-19650	VBN	denotes	determined
T11194	19637-19639	IN	denotes	as
T11193	19629-19631	NN	denotes	B6
T11192	19632-19636	NNS	denotes	mice
T11191	19625-19628	DT	denotes	the
T11680	20011-20012	NN	denotes	J
T11679	20009-20010	NN	denotes	A
T11678	20005-20008	CC	denotes	and
T11677	20002-20004	NN	denotes	B6
T11676	20013-20017	NNS	denotes	mice
T11835	20745-20746	.	denotes	.
T12723	21518-21521	IN	denotes	for
T12722	21514-21517	NN	denotes	QTL
T12721	21509-21513	IN	denotes	with
T12720	21497-21508	NNS	denotes	chromosomes
T12719	21491-21496	CD	denotes	three
T12718	21480-21490	VBZ	denotes	identifies
T12717	21474-21479	NN	denotes	assay
T12716	21465-21473	NN	denotes	bleeding
T12715	21460-21464	NN	denotes	Tail
T14575	26065-26066	.	denotes	.
T14574	26061-26065	NNS	denotes	mice
T14573	26058-26060	NN	denotes	B6
T14572	26054-26057	IN	denotes	for
T14571	26049-26053	IN	denotes	than
T14570	26039-26048	JJ	denotes	different
T14569	26035-26038	RB	denotes	not
T14568	26023-26025	CD	denotes	11
T14567	26022-26023	HYPH	denotes	-
T14566	26019-26022	NN	denotes	CSS
T14565	26026-26030	NNS	denotes	mice
T14564	26015-26018	DT	denotes	the
T14563	26012-26014	IN	denotes	in
T14562	26010-26011	-RRB-	denotes	)
T14561	26007-26008	SYM	denotes	=
T14560	26009-26010	CD	denotes	6
T14559	26005-26006	NN	denotes	n
T14558	26003-26005	,	denotes	,
T14557	26001-26003	CD	denotes	20
T14556	25999-26000	SYM	denotes	±
T19696	33662-33663	,	denotes	,
T20167	35998-35999	.	denotes	.
T20166	35994-35998	NN	denotes	time
T20165	35983-35993	NN	denotes	rebleeding
T20164	35979-35982	IN	denotes	for
T20184	36094-36095	.	denotes	.
T20183	36090-36094	NN	denotes	time
T20182	36080-36089	NN	denotes	occlusion
T20181	36071-36079	JJ	denotes	arterial
T20180	36062-36070	VB	denotes	modulate
T20179	36058-36061	CC	denotes	and
T20178	36046-36049	NN	denotes	Plg
T20177	36050-36057	NN	denotes	network
T20176	36042-36045	DT	denotes	the
T20175	36039-36041	IN	denotes	in
T20174	36028-36038	NNS	denotes	components
T20173	36023-36027	IN	denotes	with
T20172	36010-36013	MD	denotes	may
T20171	36014-36022	VB	denotes	interact
T20170	36004-36009	NNS	denotes	genes
T20169	36000-36003	DT	denotes	The
T20168	35999-36095	sentence	denotes	The genes may interact with components in the Plg network and modulate arterial occlusion time.
T20163	35975-35978	NN	denotes	QTL
T20162	35971-35974	VBD	denotes	had
T20431	36283-36292	NN	denotes	screening
T20430	36275-36278	DT	denotes	the
T20429	36272-36274	IN	denotes	of
T20428	36293-36300	VBP	denotes	suggest
T20427	36264-36271	NNS	denotes	results
T20426	36260-36263	PRP$	denotes	Our
T20425	36259-36479	sentence	denotes	Our results of the CSS screening suggest that novel or unknown genes can be used to identify the genes responsible for the traits related to arterial thrombosis, tail bleeding/rebleeding and vessel extracellular matrix.
T20424	36258-36259	.	denotes	.
T20423	36247-36258	NN	denotes	haemostasis
T20422	36243-36246	CC	denotes	and
T20421	36232-36242	NN	denotes	thrombosis
T20420	36229-36231	IN	denotes	of
T20419	36216-36228	NNS	denotes	determinants
T20418	36208-36215	JJ	denotes	genetic
T20417	36199-36207	VB	denotes	identify
T20416	36196-36198	TO	denotes	to
T20415	36183-36185	VB	denotes	be
T20414	36179-36182	MD	denotes	can
T20413	36171-36172	HYPH	denotes	/
T20412	36172-36173	NN	denotes	J
T20411	36170-36171	NN	denotes	A
T20410	36166-36169	CC	denotes	and
T20409	36163-36165	NN	denotes	B6
T20408	36174-36178	NNS	denotes	mice
T20407	36159-36162	DT	denotes	the
T20406	36156-36158	IN	denotes	in
T20405	36143-36155	VBN	denotes	demonstrated
T20404	36186-36195	VBN	denotes	exploited
T20403	36119-36130	JJ	denotes	independent
T20402	36112-36118	JJ	denotes	marked
T20401	36131-36142	NNS	denotes	differences
T20400	36108-36111	DT	denotes	The
T20532	37850-37851	:	denotes	:
T20531	37846-37850	RB	denotes	here
T20530	37834-37836	VB	denotes	be
T20529	37830-37833	MD	denotes	can
T20528	37824-37829	NN	denotes	paper
T20527	37819-37823	DT	denotes	this
T20526	37815-37818	IN	denotes	for
T20525	37837-37845	VBN	denotes	accessed
T20524	37791-37806	JJ	denotes	pre-publication
T20523	37807-37814	NN	denotes	history
T20500	36676-36677	.	denotes	.
T20499	36672-36676	NN	denotes	risk
T20498	36661-36671	JJ	denotes	thrombotic
T20497	36658-36660	IN	denotes	of
T20496	36637-36644	JJ	denotes	genetic
T20495	36645-36657	NNS	denotes	determinants
T20494	36633-36636	JJ	denotes	new
T20493	36630-36632	IN	denotes	of
T20492	36620-36629	NN	denotes	discovery
T20491	36616-36619	DT	denotes	the
T20490	36613-36615	IN	denotes	in
T20489	36607-36608	HYPH	denotes	-
T20488	36602-36607	JJ	denotes	first
T20487	36608-36612	NN	denotes	step
T20486	36600-36601	DT	denotes	a
T20485	36593-36596	NN	denotes	CSS
T20484	36589-36592	DT	denotes	the
T20564	4985-4999	NN	denotes	Identification
T20565	5000-5002	IN	denotes	of
T20566	5003-5007	NNS	denotes	mice
T20567	5008-5019	JJ	denotes	susceptible
T20568	5020-5022	CC	denotes	or
T20569	5023-5032	JJ	denotes	resistant
T20570	5033-5035	IN	denotes	to
T20571	5036-5043	NN	denotes	obesity
T20572	5043-5045	,	denotes	,
T20573	5045-5060	NN	denotes	atherosclerosis
T20574	5060-5062	,	denotes	,
T20575	5062-5065	CC	denotes	and
T20576	5066-5074	JJ	denotes	vascular
T20577	5075-5081	NN	denotes	injury
T20848	14416-14417	-LRB-	denotes	(
T20847	14393-14404	JJ	denotes	significant
T20846	14405-14415	NN	denotes	difference
T20863	14469-14470	.	denotes	.
T20862	14464-14465	HYPH	denotes	-
T20861	14463-14464	NN	denotes	t
T20860	14465-14469	NN	denotes	test
T20859	14461-14462	DT	denotes	a
T20858	14456-14460	IN	denotes	with
T20857	14445-14455	VBN	denotes	determined
T20856	14440-14444	NNS	denotes	mice
T20855	14437-14439	NN	denotes	B6
T20854	14429-14436	IN	denotes	between
T20853	14427-14428	-RRB-	denotes	)
T20852	14421-14422	SYM	denotes	<
T20851	14419-14420	NN	denotes	P
T20850	14417-14419	SYM	denotes	**
T20849	14423-14427	CD	denotes	0.01
T21154	15775-15778	CC	denotes	and
T21153	15790-15794	NN	denotes	time
T21152	15766-15774	NN	denotes	Bleeding
T21272	16200-16202	SYM	denotes	**
T21271	16198-16200	,	denotes	,
T21270	16192-16193	SYM	denotes	<
T21269	16194-16198	CD	denotes	0.05
T21268	16190-16191	NN	denotes	P
T21267	16189-16190	SYM	denotes	*
T21266	16219-16224	CD	denotes	0.001
T21265	16188-16189	-LRB-	denotes	(
T21264	16165-16176	JJ	denotes	significant
T21263	16177-16187	NN	denotes	difference
T21262	16163-16164	DT	denotes	a
T21261	16154-16162	VBP	denotes	indicate
T21260	16146-16153	NNS	denotes	Symbols
T21301	16301-16302	.	denotes	.
T21300	16293-16301	NN	denotes	genotype
T21299	16289-16292	IN	denotes	per
T21298	16284-16288	NNS	denotes	mice
T21297	16280-16281	SYM	denotes	–
T21296	16281-16283	CD	denotes	34
T21295	16278-16280	CD	denotes	10
T21294	16275-16277	IN	denotes	of
T21293	16269-16270	SYM	denotes	±
T21292	16264-16268	NN	denotes	mean
T21291	16271-16274	NN	denotes	SEM
T21290	16260-16263	DT	denotes	the
T21289	16256-16259	VBP	denotes	are
T21288	16249-16255	NNS	denotes	Values
T21287	16248-16302	sentence	denotes	Values are the mean ± SEM of 10–34 mice per genotype.
T21286	16247-16248	.	denotes	.
T21285	16240-16242	NN	denotes	WT
T21284	16237-16239	CC	denotes	or
T21283	16243-16247	NNS	denotes	mice
T21282	16234-16236	NN	denotes	B6
T21281	16226-16233	IN	denotes	between
T21280	16224-16225	-RRB-	denotes	)
T21279	16217-16218	SYM	denotes	<
T21278	16215-16216	NN	denotes	P
T21277	16212-16215	SYM	denotes	***
T21276	16210-16212	,	denotes	,
T21275	16204-16205	SYM	denotes	<
T21274	16206-16210	CD	denotes	0.01
T21273	16202-16203	NN	denotes	P
T21673	21060-21061	NN	denotes	A
T21672	21056-21059	CC	denotes	and
T21671	21064-21068	NNS	denotes	mice
T21670	21053-21055	NN	denotes	B6
T21669	21048-21052	IN	denotes	from
T21668	21035-21037	POS	denotes	's
T21667	21038-21047	NN	denotes	Trichrome
T21763	21451-21452	NN	denotes	t
T21762	21448-21450	IN	denotes	by
T21761	21437-21447	VBN	denotes	determined
T21760	21432-21436	NNS	denotes	mice
T21759	21429-21431	NN	denotes	B6
T21758	21421-21428	IN	denotes	between
T21757	21419-21420	-RRB-	denotes	)
T21756	21413-21414	SYM	denotes	<
T21755	21411-21412	NN	denotes	P
T21754	21410-21411	SYM	denotes	*
T21989	22860-22870	NNP	denotes	Bonferroni
T21988	22871-22881	NN	denotes	correction
T21987	22858-22859	DT	denotes	a
T21986	22854-22857	CC	denotes	and
T21985	22852-22854	,	denotes	,
T21984	22847-22848	HYPH	denotes	-
T21983	22846-22847	NN	denotes	t
T21982	22848-22852	NN	denotes	test
T21981	22844-22845	DT	denotes	a
T21980	22839-22843	IN	denotes	with
T21979	22823-22827	VBD	denotes	were
T21978	22819-22822	NN	denotes	CSS
T21977	22815-22818	CC	denotes	and
T21976	22810-22814	NNS	denotes	mice
T21975	22807-22809	NN	denotes	B6
T21974	22799-22806	IN	denotes	between
T21973	22828-22838	VBN	denotes	determined
T21972	22787-22798	NNS	denotes	differences
T21971	22775-22786	JJ	denotes	Statistical
T21970	22774-22935	sentence	denotes	Statistical differences between B6 mice and CSS were determined with a t-test, and a Bonferroni correction was made to determine significance value (P < 0.002).
T21969	22773-22774	.	denotes	.
T21968	22769-22773	NNS	denotes	mice
T21967	22765-22766	SYM	denotes	–
T21966	22766-22768	CD	denotes	28
T21965	22764-22765	CD	denotes	7
T21964	22761-22763	IN	denotes	of
T21963	22755-22756	SYM	denotes	±
T21962	22750-22754	NN	denotes	mean
T21961	22757-22760	NN	denotes	SEM
T21960	22746-22749	DT	denotes	the
T21959	22742-22745	VBP	denotes	are
T21958	22737-22741	NNS	denotes	Bars
T21957	22736-22774	sentence	denotes	Bars are the mean ± SEM of 7–28 mice.
T21956	22735-22736	.	denotes	.
T21955	22734-22735	-RRB-	denotes	)
T21954	22727-22734	NNS	denotes	seconds
T21953	22726-22727	-LRB-	denotes	(
T21952	22721-22725	NN	denotes	Time
T21951	22710-22720	NN	denotes	Rebleeding
T21950	22708-22710	:	denotes	:
T22017	23007-23008	.	denotes	.
T22016	23000-23001	SYM	denotes	<
T22015	23002-23007	CD	denotes	0.002
T22014	22998-22999	NN	denotes	P
T22013	22997-22998	SYM	denotes	*
T22012	22996-23008	sentence	denotes	*P < 0.002.
T22011	22995-22996	.	denotes	.
T22010	22989-22995	NNS	denotes	values
T22009	22986-22988	NN	denotes	B6
T22008	22978-22985	IN	denotes	between
T22007	22955-22966	JJ	denotes	significant
T22006	22967-22977	NN	denotes	difference
T22005	22953-22954	DT	denotes	a
T22004	22944-22952	VBP	denotes	indicate
T22003	22936-22943	NNS	denotes	Symbols
T22002	22935-22996	sentence	denotes	Symbols indicate a significant difference between B6 values.
T22001	22934-22935	.	denotes	.
T22000	22933-22934	-RRB-	denotes	)
T21999	22926-22927	SYM	denotes	<
T21998	22924-22925	NN	denotes	P
T21997	22928-22933	CD	denotes	0.002
T21996	22923-22924	-LRB-	denotes	(
T21995	22917-22922	NN	denotes	value
T21994	22904-22916	NN	denotes	significance
T21993	22894-22903	VB	denotes	determine
T21992	22891-22893	TO	denotes	to
T21991	22882-22885	VBD	denotes	was
T21990	22886-22890	VBN	denotes	made
T22302	23993-23994	-RRB-	denotes	)
T22301	23991-23993	CD	denotes	17
T22300	23990-23991	HYPH	denotes	-
T22299	23984-23990	NN	denotes	B6xCSS
T22298	23994-23996	NN	denotes	F1
T22297	23983-23984	-LRB-	denotes	(
T22296	23979-23982	CC	denotes	and
T22295	23977-23978	-RRB-	denotes	)
T22294	23974-23977	NN	denotes	5F1
T22293	23973-23974	-LRB-	denotes	(
T22292	23969-23970	-RRB-	denotes	)
T22291	23968-23969	CD	denotes	5
T22290	23967-23968	HYPH	denotes	-
T22289	23961-23967	NN	denotes	B6xCSS
T22288	23970-23972	NN	denotes	F1
T22287	23960-23961	-LRB-	denotes	(
T22286	23958-23960	,	denotes	,
T22285	23954-23958	NNS	denotes	mice
T22284	23942-23953	JJ	denotes	heterosomic
T22283	23939-23941	IN	denotes	in
T22282	23927-23931	VBD	denotes	were
T22281	23925-23926	-RRB-	denotes	)
T22280	23918-23925	NNS	denotes	seconds
T22279	23917-23918	-LRB-	denotes	(
T22278	23912-23916	NN	denotes	Time
T22277	23901-23911	NN	denotes	Rebleeding
T22276	23899-23901	:	denotes	:
T22275	23898-23899	NN	denotes	B
T22274	23892-23897	NN	denotes	Panel
T22273	23888-23891	CC	denotes	and
T22272	23886-23887	-RRB-	denotes	)
T22271	23879-23886	NNS	denotes	seconds
T22270	23878-23879	-LRB-	denotes	(
T22269	23873-23877	NN	denotes	Time
T22268	23864-23872	NN	denotes	Bleeding
T22267	23862-23864	:	denotes	:
T22266	23932-23938	VBN	denotes	tested
T22265	23861-23862	NN	denotes	A
T22264	23855-23860	NN	denotes	Panel
T22263	23854-24066	sentence	denotes	Panel A: Bleeding Time (seconds) and Panel B: Rebleeding Time (seconds) were tested in heterosomic mice, (B6xCSS-5)F1 (5F1) and (B6xCSS-17)F1 (17F1) and doubly heterosomic mice for chromosomes 5 and 17 (5 × 17).
T22262	23853-23854	.	denotes	.
T22261	23838-23841	NN	denotes	CSS
T22260	23842-23853	NNS	denotes	backcrosses
T22259	23834-23837	DT	denotes	the
T22383	24339-24340	.	denotes	.
T22382	24333-24334	SYM	denotes	<
T22715	26310-26313	CC	denotes	and
T22714	26308-26309	CD	denotes	5
T22713	26296-26307	NNS	denotes	chromosomes
T22712	26292-26295	IN	denotes	for
T22711	26287-26291	NNS	denotes	mice
T22710	26275-26286	JJ	denotes	heterosomic
T22709	26268-26274	RB	denotes	doubly
T22708	26264-26267	CC	denotes	and
T22707	26262-26263	-RRB-	denotes	)
T22706	26258-26262	NN	denotes	17F1
T23021	27541-27544	CC	denotes	and
T22783	26595-26596	.	denotes	.
T22782	26589-26590	SYM	denotes	<
T22781	26591-26595	CD	denotes	0.01
T22780	26587-26588	NN	denotes	P
T22779	26586-26587	SYM	denotes	*
T22778	26585-26596	sentence	denotes	*P < 0.01.
T22777	26584-26585	.	denotes	.
T22776	26578-26584	NNS	denotes	values
T22775	26575-26577	NN	denotes	B6
T22774	26567-26574	IN	denotes	between
T22773	26544-26555	JJ	denotes	significant
T22772	26556-26566	NN	denotes	difference
T22771	26542-26543	DT	denotes	a
T22770	26533-26541	VBP	denotes	indicate
T22769	26525-26532	NNS	denotes	Symbols
T22768	26524-26585	sentence	denotes	Symbols indicate a significant difference between B6 values.
T22767	26523-26524	.	denotes	.
T22766	26522-26523	-RRB-	denotes	)
T22765	26516-26517	SYM	denotes	<
T22764	26514-26515	NN	denotes	P
T22763	26518-26522	CD	denotes	0.01
T22762	26513-26514	-LRB-	denotes	(
T22761	26507-26512	NN	denotes	value
T22760	26494-26506	NN	denotes	significance
T23027	27555-27556	-RRB-	denotes	)
T23026	27553-27555	CD	denotes	17
T23025	27552-27553	HYPH	denotes	-
T23024	27546-27552	NN	denotes	B6xCSS
T23023	27556-27558	NN	denotes	F1
T23022	27545-27546	-LRB-	denotes	(
T23020	27539-27540	-RRB-	denotes	)
T23019	27536-27539	NN	denotes	5F1
T23018	27535-27536	-LRB-	denotes	(
T23017	27531-27532	-RRB-	denotes	)
T23016	27530-27531	CD	denotes	5
T23015	27529-27530	HYPH	denotes	-
T23014	27532-27534	NN	denotes	F1
T23013	27523-27529	NN	denotes	B6xCSS
T23012	27522-27523	-LRB-	denotes	(
T23011	27520-27522	,	denotes	,
T23010	27516-27520	NNS	denotes	mice
T23009	27504-27515	JJ	denotes	heterosomic
T23008	27501-27503	IN	denotes	in
T23007	27486-27489	VBD	denotes	was
T23006	27490-27500	VBN	denotes	determined
T23005	27481-27485	NN	denotes	time
T23004	27471-27480	NN	denotes	Occlusion
T23003	27470-27629	sentence	denotes	Occlusion time was determined in heterosomic mice, (B6xCSS-5)F1 (5F1) and (B6xCSS-17)F1 (17F1), and doubly heterosomic mice for chromosomes 5 and 17 (5 × 17).
T23002	27469-27470	.	denotes	.
T23001	27454-27457	NN	denotes	CSS
T23000	27458-27469	NNS	denotes	backcrosses
T22999	27450-27453	DT	denotes	the
T22998	27447-27449	IN	denotes	in
T22997	27442-27446	NN	denotes	time
T22996	27432-27441	NN	denotes	occlusion
T22995	27423-27431	JJ	denotes	Arterial
T23087	27821-27825	CD	denotes	0.02
T23086	27816-27817	-LRB-	denotes	(
T23085	27810-27815	NN	denotes	value
T23084	27797-27809	NN	denotes	significance
T23083	27787-27796	VB	denotes	determine
T23082	27784-27786	TO	denotes	to
T23081	27775-27778	VBD	denotes	was
T23080	27779-27783	VBN	denotes	made
T23079	27753-27763	NNP	denotes	Bonferroni
T23078	27764-27774	NN	denotes	correction
T23077	27751-27752	DT	denotes	a
T23076	27747-27750	CC	denotes	and
T23075	27745-27747	,	denotes	,
T23074	27740-27741	HYPH	denotes	-
T23073	27739-27740	NN	denotes	t
T23072	27741-27745	NN	denotes	test
T23071	27737-27738	DT	denotes	a
T23070	27732-27736	IN	denotes	with
T23069	27716-27720	VBD	denotes	were
T23068	27712-27715	NN	denotes	CSS
T23067	27708-27711	CC	denotes	and
T23154	18128-18133	NN	denotes	mouse
T23153	18121-18127	JJ	denotes	inbred
T23152	18118-18119	HYPH	denotes	/
T23151	18119-18120	NN	denotes	J
T23150	18117-18118	NN	denotes	A
T23149	18113-18116	CC	denotes	and
T23148	18134-18141	NNS	denotes	strains
T23147	18110-18112	NN	denotes	B6
T23146	18107-18109	IN	denotes	in
T23145	18089-18095	NN	denotes	System
T23144	18077-18088	NN	denotes	Plasminogen
T23143	18073-18076	CC	denotes	and
T23142	18096-18106	NNS	denotes	Parameters
T23141	18061-18072	NN	denotes	Coagulation
T9603	15413-15414	SYM	denotes	-
T9602	15412-15413	HYPH	denotes	/
T9601	15411-15412	SYM	denotes	-
T9600	15408-15411	NN	denotes	Plg
T9599	15415-15419	NNS	denotes	mice
T9598	15404-15407	DT	denotes	the
T20522	37787-37790	DT	denotes	The
T5778	9766-9767	CD	denotes	5
T13006	22614-22615	.	denotes	.
T13005	22613-22614	NN	denotes	%
T13004	22611-22613	CD	denotes	85
T13003	22596-22606	NN	denotes	percentage
T13002	22592-22595	DT	denotes	the
T13001	22584-22585	HYPH	denotes	/
T13000	22585-22586	NN	denotes	J
T12999	22583-22584	NN	denotes	A
T12998	22587-22591	NNS	denotes	mice
T12997	22579-22582	DT	denotes	the
T12996	22607-22610	VBD	denotes	was
T12995	22575-22578	IN	denotes	for
T12994	22571-22574	CC	denotes	and
T12993	22569-22570	NN	denotes	%
T12992	22568-22569	CD	denotes	7
T12991	22560-22563	NN	denotes	sec
T12990	22556-22559	CD	denotes	600
T12989	22553-22555	IN	denotes	of
T12988	22537-22547	NN	denotes	rebleeding
T12987	22548-22552	NN	denotes	time
T12986	22535-22536	DT	denotes	a
T12985	22530-22534	IN	denotes	with
T12984	22525-22529	NNS	denotes	mice
T12983	22522-22524	NN	denotes	B6
T12982	22519-22521	IN	denotes	of
T12981	22564-22567	VBD	denotes	was
T12980	22508-22518	NN	denotes	percentage
T12979	22504-22507	DT	denotes	The
T12978	22503-22615	sentence	denotes	The percentage of B6 mice with a rebleeding time of 600 sec was 7% and for the A/J mice the percentage was 85%.
T12977	22502-22503	.	denotes	.
T12976	22499-22501	CD	denotes	46
T12975	22498-22499	:	denotes	–
T12974	22501-22502	NN	denotes	%
T12973	22494-22495	HYPH	denotes	-
T12972	22495-22498	NN	denotes	A17
T12971	22491-22494	NN	denotes	CSS
T12970	22487-22490	CC	denotes	and
T12969	22483-22485	NN	denotes	60
T12968	22482-22483	:	denotes	–
T12967	22480-22482	CD	denotes	11
T12966	22479-22480	HYPH	denotes	-
T12965	22485-22486	NN	denotes	%
T12964	22476-22479	NN	denotes	CSS
T13036	23167-23170	DT	denotes	the
T13035	23163-23166	IN	denotes	for
T13034	23158-23162	NNS	denotes	mice
T13033	23146-23157	JJ	denotes	heterosomic
T13032	23138-23145	VB	denotes	produce
T13031	23135-23137	TO	denotes	to
T13030	23130-23134	NNS	denotes	mice
T13029	23127-23129	NN	denotes	B6
T13028	23122-23126	IN	denotes	with
T13027	23109-23113	VBD	denotes	were
T13026	23114-23121	VBN	denotes	crossed
T13025	23104-23108	WDT	denotes	that
T13024	23099-23103	NNS	denotes	mice
T13023	23096-23098	IN	denotes	of
T13022	23088-23095	NN	denotes	progeny
T13021	23084-23087	DT	denotes	the
T13020	23079-23083	IN	denotes	from
T13019	23072-23078	NNS	denotes	values
T13018	23069-23071	IN	denotes	to
T13017	23055-23059	VBD	denotes	were
T13016	23051-23054	NN	denotes	CSS
T13015	23047-23050	CC	denotes	and
T13014	23032-23038	NN	denotes	parent
T13013	23039-23046	NNS	denotes	strains
T13012	23028-23031	DT	denotes	the
T13011	23025-23027	IN	denotes	in
T13010	23060-23068	VBN	denotes	compared
T13009	23020-23024	NN	denotes	time
T13008	23009-23019	NN	denotes	Rebleeding
T13007	22615-23235	sentence	denotes	Figure 4 Bleeding and rebleeding time in the CSS. Panel A: Bleeding Time (seconds). Panel B: Rebleeding Time (seconds). Bars are the mean ± SEM of 7–28 mice. Statistical differences between B6 mice and CSS were determined with a t-test, and a Bonferroni correction was made to determine significance value (P < 0.002). Symbols indicate a significant difference between B6 values. *P < 0.002. Rebleeding time in the parent strains and CSS were compared to values from the progeny of mice that were crossed with B6 mice to produce heterosomic mice for the CSS-5, (B6xCSS-5)F1 and CSS-17 (B6xCSS-17)F1 strains (Figure 5).
T9625	15511-15513	IN	denotes	to
T9624	15502-15510	VBN	denotes	compared
T9623	15495-15496	SYM	denotes	-
T9622	15494-15495	HYPH	denotes	/
T9621	15493-15494	SYM	denotes	-
T9620	15492-15493	CD	denotes	1
T9619	15491-15492	HYPH	denotes	-
T9618	15497-15501	NNS	denotes	mice
T9617	15488-15491	NN	denotes	PAI
T9616	15485-15487	IN	denotes	in
T9615	15475-15484	JJ	denotes	different
T9614	15471-15474	RB	denotes	not
T9613	15467-15470	VBD	denotes	was
T9612	15462-15466	NN	denotes	time
T9611	15453-15461	NN	denotes	Bleeding
T9610	15452-15522	sentence	denotes	Bleeding time was not different in PAI-1-/- mice compared to B6 mice.
T9609	15451-15452	.	denotes	.
T9608	15435-15439	NNS	denotes	mice
T9607	15440-15451	NNS	denotes	littermates
T9606	15432-15434	NN	denotes	WT
T9605	15429-15431	IN	denotes	to
T9604	15420-15428	VBN	denotes	compared
T9691	16393-16402	NN	denotes	cessation
T9690	16389-16392	DT	denotes	the
T9689	16381-16388	IN	denotes	between
T9688	16376-16380	NN	denotes	time
T9687	16372-16375	DT	denotes	the
T9686	16369-16371	IN	denotes	as
T9685	16356-16359	VBD	denotes	was
T9684	16354-16356	,	denotes	,
T9683	16345-16354	NN	denotes	stability
T9682	16336-16344	NN	denotes	thrombus
T9681	16333-16335	IN	denotes	of
T9680	16323-16332	NN	denotes	indicator
T9679	16320-16322	DT	denotes	an
T9678	16318-16320	,	denotes	,
T9677	16360-16368	VBN	denotes	measured
T9676	16314-16318	NN	denotes	time
T9675	16303-16313	NN	denotes	Rebleeding
T9674	15755-16464	sentence	denotes	Figure 2 Bleeding and rebleeding time in B6, A/J, Lepob, Plg-/- and PAI-1-/- mice. Panel A, B: Bleeding time (seconds) and Panel C, D: Rebleeding time (seconds). To determine statistical differences, values from B6 and A/J and from WT and Plg-/- littermates were compared with a t-test, and values from B6, PAI-1-/- and Lepob were compared by a one-way ANOVA and a Newman-Keuls post-test. Symbols indicate a significant difference (P < 0.05, P < 0.01, **P < 0.001) between B6 or WT mice. Values are the mean ± SEM of 10–34 mice per genotype. Rebleeding time, an indicator of thrombus stability, was measured as the time between the cessation of bleeding and the start of the second bleeding (Figure 2B).
T1007	0-7	JJ	denotes	Genetic
T3465	4400-4401	:	denotes	;
T3466	4402-4403	NN	denotes	A
T3615	5781-5785	VBN	denotes	used
T3614	5768-5775	NNS	denotes	markers
T3613	5760-5767	JJ	denotes	Genetic
T3612	5759-5868	sentence	denotes	Genetic markers were used to identify homozygosity in the background (B6) and the individual A/J chromosome.
T3611	5758-5759	.	denotes	.
T3610	5751-5753	NN	denotes	B6
T3609	5754-5758	NNS	denotes	mice
T3608	5747-5750	DT	denotes	the
T3607	5744-5746	IN	denotes	to
T3606	5719-5731	RB	denotes	successively
T3605	5714-5718	VBD	denotes	were
T3604	5705-5706	HYPH	denotes	/
T3603	5706-5707	NN	denotes	J
T3602	5704-5705	NN	denotes	A
T3601	5702-5703	SYM	denotes	×
T3600	5699-5701	NN	denotes	B6
T3599	5708-5713	NN	denotes	cross
T3598	5697-5698	DT	denotes	a
T3597	5694-5696	IN	denotes	of
T3596	5686-5693	NN	denotes	progeny
T3595	5682-5685	DT	denotes	the
T3594	5732-5743	VBN	denotes	backcrossed
T3593	5676-5681	WRB	denotes	where
T3592	5659-5667	NN	denotes	breeding
T3591	5657-5658	''	denotes	"
T3590	5648-5649	HYPH	denotes	-
T3589	5649-5657	VBN	denotes	assisted
T3588	5642-5648	NN	denotes	marker
T3587	5641-5642	``	denotes	"
T3586	5668-5675	NN	denotes	program
T3585	5639-5640	DT	denotes	a
T3584	5636-5638	IN	denotes	by
T3583	5634-5635	-RRB-	denotes	]
T3582	5632-5634	CD	denotes	11
T3581	5631-5632	-LRB-	denotes	[
T3580	5617-5620	VBD	denotes	was
T3579	5615-5616	-RRB-	denotes	)
T3578	5612-5615	NNS	denotes	CSS
T3577	5611-5612	-LRB-	denotes	(
T3576	5590-5602	NN	denotes	substitution
T3575	5603-5610	NNS	denotes	strains
T3574	5579-5589	NN	denotes	chromosome
T3573	5576-5578	IN	denotes	of
T3572	5621-5630	VBN	denotes	generated
T3571	5570-5575	NN	denotes	panel
T3570	5570-5759	sentence	denotes	panel of chromosome substitution strains (CSS) was generated [11] by a "marker-assisted" breeding program where the progeny of a B6 × A/J cross were successively backcrossed to the B6 mice.
T3569	5568-5569	NN	denotes	A
T3568	5568-5570	sentence	denotes	A
R43	T1059	T1058	prep	in,differences
R44	T1060	T1059	pobj	susceptibility,in
R45	T1061	T1060	prep	to,susceptibility
R46	T1062	T1061	pobj	obesity,to
R1	T1008	T1010	nsubj	background,determines
R2	T1011	T1010	dobj	response,determines
R3	T1012	T1011	prep	to,response
R4	T1013	T1012	pobj	hemostasis,to
R5	T1014	T1013	cc	and,hemostasis
R6	T1015	T1013	conj	thrombosis,hemostasis
R7	T1020	T1021	nsubj	Thrombosis,is
R8	T1022	T1023	det	the,consequence
R9	T1023	T1021	attr	consequence,is
R13	T1027	T1023	prep	of,consequence
R14	T1028	T1029	amod	cardiovascular,diseases
R15	T1029	T1027	pobj	diseases,of
R16	T1030	T1029	punct	", ",diseases
R17	T1031	T1032	det	the,cause
R18	T1032	T1029	appos	cause,diseases
R20	T1034	T1032	prep	of,cause
R21	T1035	T1034	pobj	mortality,of
R22	T1036	T1035	cc	and,mortality
R23	T1037	T1035	conj	morbidity,mortality
R24	T1038	T1032	prep	in,cause
R25	T1039	T1040	amod	Western,countries
R26	T1040	T1038	pobj	countries,in
R27	T1041	T1021	punct	.,is
R28	T1043	T1044	nummod	Two,strains
R29	T1044	T1047	nsubj	strains,have
R32	T1048	T1044	punct	", ",strains
R33	T1049	T1050	compound	C57BL,6J
R34	T1050	T1044	appos	6J,strains
R36	T1052	T1050	cc	and,6J
R37	T1053	T1054	compound	A,J
R38	T1054	T1050	conj	J,6J
R40	T1056	T1047	punct	", ",have
R41	T1057	T1058	amod	marked,differences
R42	T1058	T1047	dobj	differences,have
R47	T1063	T1062	punct	", ",obesity
R48	T1064	T1062	conj	atherosclerosis,obesity
R49	T1065	T1064	punct	", ",atherosclerosis
R50	T1066	T1064	cc	and,atherosclerosis
R51	T1067	T1068	compound	vessel,remodeling
R52	T1068	T1064	conj	remodeling,atherosclerosis
R53	T1069	T1047	punct	.,have
R54	T1071	T1072	advmod	However,is
R55	T1073	T1072	punct	", ",is
R56	T1074	T1072	nsubj	it,is
R57	T1075	T1072	acomp	unclear,is
R58	T1076	T1077	advmod	how,influence
R59	T1077	T1072	ccomp	influence,is
R61	T1079	T1077	nsubj	backgrounds,influence
R62	T1080	T1079	amod	diverse,backgrounds
R63	T1081	T1079	amod	genetic,backgrounds
R64	T1082	T1077	dobj	pathways,influence
R65	T1083	T1082	acl	known,pathways
R66	T1084	T1085	aux	to,regulate
R67	T1085	T1083	xcomp	regulate,known
R68	T1086	T1085	dobj	thrombosis,regulate
R69	T1087	T1086	cc	and,thrombosis
R70	T1088	T1086	conj	hemostasis,thrombosis
R71	T1089	T1072	punct	.,is
R72	T1091	T1092	det	The,objective
R73	T1092	T1093	nsubj	objective,was
R74	T1094	T1092	prep	of,objective
R75	T1095	T1096	det	this,study
R76	T1096	T1094	pobj	study,of
R77	T1097	T1098	aux	to,evaluate
R78	T1098	T1093	xcomp	evaluate,was
R79	T1099	T1098	dobj	thrombosis,evaluate
R80	T1100	T1099	cc	and,thrombosis
R81	T1101	T1099	conj	hemostasis,thrombosis
R82	T1102	T1098	prep	in,evaluate
R83	T1103	T1104	det	these,strains
R84	T1104	T1102	pobj	strains,in
R87	T1107	T1098	cc	and,evaluate
R88	T1108	T1098	conj	determine,evaluate
R89	T1109	T1110	det	the,response
R90	T1110	T1108	dobj	response,determine
R92	T1112	T1110	prep	of,response
R93	T1113	T1114	compound	A,J
R94	T1114	T1116	compound	J,chromosomes
R96	T1116	T1112	pobj	chromosomes,of
R97	T1117	T1108	prep	in,determine
R98	T1118	T1119	det	the,background
R99	T1119	T1117	pobj	background,in
R101	T1121	T1119	compound	6J,background
R102	T1122	T1121	punct	/,6J
R103	T1123	T1093	punct	.,was
R104	T1127	T1128	nmod	A,J
R105	T1128	T1130	nmod	J,mice
R107	T1130	T1135	nsubjpass	mice,evaluated
R110	T1133	T1128	conj	6J,J
R111	T1134	T1133	punct	/,6J
R112	T1136	T1135	auxpass	were,evaluated
R113	T1137	T1135	prep	for,evaluated
R114	T1138	T1137	pobj	differences,for
R115	T1139	T1138	prep	in,differences
R116	T1140	T1139	pobj	thrombosis,in
R117	T1141	T1140	cc	and,thrombosis
R118	T1142	T1140	conj	hemostasis,thrombosis
R119	T1143	T1135	punct	.,evaluated
R120	T1145	T1146	det	A,thrombus
R121	T1146	T1147	nsubjpass	thrombus,induced
R122	T1148	T1147	auxpass	was,induced
R123	T1149	T1147	prep	in,induced
R124	T1150	T1151	det	the,artery
R125	T1151	T1149	pobj	artery,in
R127	T1153	T1147	prep	by,induced
R128	T1154	T1153	pobj	application,by
R129	T1155	T1154	prep	of,application
R130	T1156	T1157	det	the,carotid
R131	T1157	T1155	pobj	carotid,of
R133	T1159	T1154	prep	to,application
R134	T1160	T1161	amod	ferric,chloride
R135	T1161	T1159	pobj	chloride,to
R136	T1162	T1147	cc	and,induced
R137	T1163	T1164	compound	blood,flow
R138	T1164	T1165	nsubj	flow,measured
R139	T1165	T1147	conj	measured,induced
R140	T1166	T1167	mark	until,occluded
R141	T1167	T1165	advcl	occluded,measured
R144	T1170	T1165	punct	.,measured
R145	T1172	T1173	nmod	Bleeding,times
R146	T1173	T1176	nsubjpass	times,determined
R149	T1177	T1173	punct	", ",times
R150	T1178	T1173	prep	as,times
R151	T1179	T1180	amod	surrogate,markers
R152	T1180	T1178	pobj	markers,as
R153	T1181	T1180	prep	for,markers
R154	T1182	T1181	pobj	thrombosis,for
R155	T1183	T1182	cc	and,thrombosis
R156	T1184	T1182	conj	hemostasis,thrombosis
R157	T1185	T1176	punct	", ",determined
R158	T1186	T1176	auxpass	were,determined
R159	T1187	T1176	prep	after,determined
R160	T1188	T1187	pcomp	clipping,after
R161	T1189	T1190	det	the,tail
R162	T1190	T1188	dobj	tail,clipping
R163	T1191	T1188	cc	and,clipping
R164	T1192	T1188	conj	placing,clipping
R165	T1193	T1192	prep	in,placing
R166	T1194	T1195	amod	warm,saline
R167	T1195	T1193	pobj	saline,in
R168	T1196	T1176	punct	.,determined
R169	T1198	T1199	compound	Twenty,one
R170	T1199	T1201	nummod	one,strains
R172	T1201	T1204	nsubjpass	strains,screened
R175	T1205	T1201	punct	", ",strains
R176	T1206	T1207	compound	A,J
R177	T1207	T1209	compound	J,chromosomes
R179	T1209	T1201	appos	chromosomes,strains
R180	T1210	T1209	prep	in,chromosomes
R181	T1211	T1212	det	a,background
R182	T1212	T1210	pobj	background,in
R184	T1214	T1212	compound	6J,background
R185	T1215	T1214	punct	/,6J
R186	T1216	T1204	punct	", ",screened
R187	T1217	T1204	auxpass	were,screened
R188	T1218	T1204	prep	for,screened
R189	T1219	T1218	pobj	response,for
R190	T1220	T1219	prep	to,response
R191	T1221	T1222	det	the,assay
R192	T1222	T1220	pobj	assay,to
R195	T1225	T1204	punct	.,screened
R196	T1229	T1230	compound	Thrombus,occlusion
R197	T1230	T1231	compound	occlusion,time
R198	T1231	T1232	nsubjpass	time,decreased
R199	T1233	T1232	auxpass	was,decreased
R200	T1234	T1232	advmod	markedly,decreased
R201	T1235	T1232	prep	in,decreased
R202	T1236	T1237	det	the,mice
R203	T1237	T1235	pobj	mice,in
R205	T1239	T1237	compound	J,mice
R206	T1240	T1239	punct	/,J
R207	T1241	T1232	prep	compared,decreased
R208	T1242	T1241	prep	to,compared
R209	T1243	T1244	compound	C57BL,6J
R210	T1244	T1246	compound	6J,mice
R212	T1246	T1242	pobj	mice,to
R213	T1247	T1232	punct	.,decreased
R214	T1249	T1250	compound	Tail,bleeding
R215	T1250	T1251	compound	bleeding,time
R216	T1251	T1252	nsubj	time,was
R217	T1253	T1252	acomp	similar,was
R218	T1254	T1252	prep	in,was
R219	T1255	T1256	det	the,strains
R220	T1256	T1254	pobj	strains,in
R222	T1258	T1252	punct	", ",was
R223	T1259	T1252	cc	but,was
R224	T1260	T1261	compound	rebleeding,time
R225	T1261	T1262	nsubjpass	time,increased
R226	T1262	T1252	conj	increased,was
R229	T1265	T1262	prep	in,increased
R230	T1266	T1267	det	the,mice
R231	T1267	T1265	pobj	mice,in
R233	T1269	T1267	compound	J,mice
R234	T1270	T1269	punct	/,J
R235	T1271	T1262	prep	compared,increased
R236	T1272	T1271	prep	to,compared
R237	T1273	T1274	compound	C57BL,6J
R238	T1274	T1276	compound	6J,mice
R240	T1276	T1272	pobj	mice,to
R241	T1277	T1262	punct	.,increased
R242	T1279	T1280	compound	Coagulation,times
R243	T1280	T1281	nsubj	times,were
R244	T1282	T1280	cc	and,times
R245	T1283	T1284	compound	tail,morphology
R246	T1284	T1280	conj	morphology,times
R247	T1285	T1281	acomp	similar,were
R248	T1286	T1281	punct	", ",were
R249	T1287	T1281	cc	but,were
R250	T1288	T1289	compound	tail,collagen
R251	T1289	T1290	compound	collagen,content
R252	T1290	T1291	nsubj	content,was
R253	T1291	T1281	conj	was,were
R254	T1292	T1291	acomp	higher,was
R255	T1293	T1291	prep	in,was
R256	T1294	T1295	compound	A,J
R257	T1295	T1293	pobj	J,in
R259	T1297	T1291	prep	than,was
R260	T1298	T1299	compound	C57BL,6J
R261	T1299	T1297	pobj	6J,than
R263	T1301	T1291	dobj	mice,was
R264	T1302	T1291	punct	.,was
R265	T1304	T1305	nummod	Three,strains
R266	T1305	T1308	nsubjpass	strains,identified
R269	T1309	T1305	punct	", ",strains
R270	T1310	T1311	compound	B6,Chr5A
R271	T1311	T1313	compound	Chr5A,J
R273	T1313	T1305	appos	J,strains
R275	T1315	T1313	punct	", ",J
R276	T1316	T1317	compound	B6,Chr11A
R277	T1317	T1319	compound	Chr11A,J
R279	T1319	T1313	conj	J,J
R281	T1321	T1319	punct	", ",J
R282	T1322	T1319	cc	and,J
R283	T1323	T1324	compound	B6,Chr17A
R284	T1324	T1326	compound	Chr17A,J
R286	T1326	T1319	conj	J,J
R288	T1328	T1308	punct	", ",identified
R289	T1329	T1308	auxpass	were,identified
R290	T1330	T1308	prep	with,identified
R291	T1331	T1332	amod	increased,time
R292	T1332	T1330	pobj	time,with
R294	T1334	T1332	punct	", ",time
R295	T1335	T1336	det	a,phenotype
R296	T1336	T1332	appos	phenotype,time
R297	T1337	T1336	amod	similar,phenotype
R298	T1338	T1337	prep	to,similar
R299	T1339	T1340	compound	A,J
R300	T1340	T1342	compound	J,mice
R302	T1342	T1338	pobj	mice,to
R303	T1343	T1308	punct	.,identified
R304	T1345	T1346	nsubj	Mice,had
R305	T1347	T1345	amod	heterosomic,Mice
R306	T1348	T1347	prep	for,heterosomic
R307	T1349	T1350	nmod	chromosomes,5
R308	T1350	T1348	pobj	5,for
R309	T1351	T1350	cc	or,5
R310	T1352	T1350	conj	17,5
R311	T1353	T1354	compound	rebleeding,times
R312	T1354	T1346	dobj	times,had
R313	T1355	T1354	amod	similar,times
R314	T1356	T1355	prep	to,similar
R315	T1357	T1358	compound	C57BL,6J
R316	T1358	T1360	compound	6J,mice
R318	T1360	T1356	pobj	mice,to
R319	T1361	T1346	punct	", ",had
R320	T1362	T1346	cc	but,had
R321	T1363	T1364	prep	when,crossed
R322	T1364	T1384	advcl	crossed,restored
R324	T1366	T1364	nsubjpass	strains,crossed
R325	T1367	T1366	nummod	two,strains
R326	T1368	T1366	compound	chromosome,strains
R327	T1369	T1366	compound	substitution,strains
R330	T1372	T1374	compound	Chr5A,J
R331	T1373	T1372	punct	-,Chr5A
R332	T1374	T1366	appos	J,strains
R333	T1375	T1374	punct	/,J
R336	T1378	T1380	compound	Chr17A,J
R337	T1379	T1378	punct	-,Chr17A
R338	T1380	T1374	conj	J,J
R339	T1381	T1380	punct	/,J
R342	T1384	T1346	conj	restored,had
R345	T1387	T1384	nsubjpass	phenotype,restored
R346	T1388	T1389	compound	A,J
R348	T1390	T1389	punct	/,J
R350	T1392	T1384	prep	in,restored
R351	T1393	T1394	det	these,progeny
R352	T1394	T1392	pobj	progeny,in
R355	T1397	T1384	punct	.,restored
R356	T1401	T1402	det	These,results
R357	T1402	T1403	nsubj	results,indicate
R358	T1404	T1405	mark	that,is
R359	T1405	T1403	ccomp	is,indicate
R366	T1412	T1413	advmod	remarkably,different
R367	T1413	T1405	acomp	different,is
R368	T1414	T1405	prep	in,is
R369	T1415	T1416	nmod	C57BL,J
R370	T1416	T1421	compound	J,mice
R375	T1421	T1414	pobj	mice,in
R376	T1422	T1403	punct	.,indicate
R377	T1424	T1425	nummod	Three,strains
R378	T1425	T1431	nsubjpass	strains,identified
R380	T1427	T1425	compound	J,strains
R381	T1428	T1427	punct	/,J
R384	T1432	T1431	auxpass	were,identified
R385	T1433	T1434	dep	that,expressed
R386	T1434	T1431	ccomp	expressed,identified
R387	T1435	T1436	det	a,phenotype
R388	T1436	T1434	dobj	phenotype,expressed
R389	T1437	T1436	amod	similar,phenotype
R390	T1438	T1437	prep	to,similar
R391	T1439	T1440	compound	A,J
R392	T1440	T1438	pobj	J,to
R394	T1442	T1431	prep	for,identified
R395	T1443	T1442	pobj	rebleeding,for
R396	T1444	T1431	punct	", ",identified
R397	T1445	T1446	det	the,background
R398	T1446	T1450	nsubj	background,modify
R400	T1448	T1446	compound	6J,background
R401	T1449	T1448	punct	/,6J
R402	T1450	T1431	conj	modify,identified
R404	T1452	T1453	det	the,phenotype
R405	T1453	T1450	dobj	phenotype,modify
R407	T1455	T1453	compound	J,phenotype
R408	T1456	T1455	punct	/,J
R409	T1457	T1450	punct	", ",modify
R410	T1458	T1450	cc	and,modify
R411	T1459	T1460	det	the,combination
R412	T1460	T1461	nsubj	combination,restore
R413	T1461	T1450	conj	restore,modify
R416	T1464	T1462	pobj	QTL,of
R417	T1465	T1466	compound	A,J
R419	T1467	T1466	punct	/,J
R421	T1469	T1470	det	the,phenotype
R422	T1470	T1461	dobj	phenotype,restore
R423	T1471	T1461	punct	.,restore
R424	T1473	T1474	det	The,backgrounds
R425	T1474	T1477	nsubj	backgrounds,suggest
R428	T1478	T1474	cc	and,backgrounds
R429	T1479	T1474	conj	differences,backgrounds
R430	T1480	T1479	prep	in,differences
R431	T1481	T1480	pobj	response,in
R432	T1482	T1481	prep	to,response
R433	T1483	T1484	amod	vascular,injury
R434	T1484	T1485	npadvmod	injury,induced
R435	T1485	T1486	amod	induced,thrombosis
R436	T1486	T1482	pobj	thrombosis,to
R437	T1487	T1486	cc	and,thrombosis
R438	T1488	T1489	det	the,assay
R439	T1489	T1486	conj	assay,thrombosis
R442	T1492	T1477	punct	", ",suggest
R443	T1493	T1494	det	the,potential
R444	T1494	T1477	dobj	potential,suggest
R445	T1495	T1494	prep	for,potential
R446	T1496	T1495	pcomp	identifying,for
R447	T1497	T1498	amod	novel,determinants
R448	T1498	T1496	dobj	determinants,identifying
R450	T1500	T1498	prep	of,determinants
R451	T1501	T1502	amod	thrombotic,risk
R452	T1502	T1500	pobj	risk,of
R453	T1503	T1477	punct	.,suggest
R454	T1007	T1008	amod	Genetic,background
R456	T3130	T3131	compound	Family,history
R457	T3131	T3132	nsubj	history,is
R458	T3133	T3134	punct	[,1
R459	T3134	T3131	parataxis	1,history
R460	T3135	T3134	punct	],1
R461	T3136	T3137	det	the,factor
R462	T3137	T3132	attr	factor,is
R463	T3138	T3137	amod	strongest,factor
R464	T3139	T3137	compound	risk,factor
R465	T3140	T3137	prep	for,factor
R466	T3141	T3142	amod	cardiovascular,diseases
R467	T3142	T3140	pobj	diseases,for
R468	T3143	T3142	punct	(,diseases
R469	T3144	T3142	appos	CVD,diseases
R470	T3145	T3132	punct	),is
R471	T3146	T3132	punct	.,is
R472	T3148	T3149	mark	While,identified
R473	T3149	T3157	advcl	identified,account
R474	T3150	T3151	det	a,number
R475	T3151	T3149	nsubjpass	number,identified
R476	T3152	T3151	prep	of,number
R477	T3153	T3154	amod	genetic,mutations
R478	T3154	T3152	pobj	mutations,of
R479	T3155	T3149	aux	have,identified
R480	T3156	T3149	auxpass	been,identified
R481	T3158	T3157	punct	", ",account
R482	T3159	T3157	nsubj	these,account
R483	T3160	T3157	prep	for,account
R484	T3161	T3162	advmod	only,percentage
R485	T3162	T3160	pobj	percentage,for
R486	T3163	T3162	det	a,percentage
R487	T3164	T3162	amod	small,percentage
R488	T3165	T3162	prep	of,percentage
R489	T3166	T3167	det	the,CVD
R490	T3167	T3165	pobj	CVD,of
R491	T3168	T3167	prep	in,CVD
R492	T3169	T3170	amod	human,populations
R493	T3170	T3168	pobj	populations,in
R494	T3171	T3157	punct	.,account
R495	T3173	T3174	compound	Thrombus,formation
R496	T3174	T3175	nsubj	formation,is
R497	T3176	T3174	prep	on,formation
R498	T3177	T3178	amod	fissured,plaques
R500	T3179	T3178	amod	atherosclerotic,plaques
R501	T3180	T3181	det	the,event
R503	T3182	T3181	amod	precipitating,event
R504	T3183	T3181	prep	in,event
R505	T3184	T3185	det	the,transition
R506	T3185	T3183	pobj	transition,in
R507	T3186	T3185	prep	from,transition
R508	T3187	T3188	det	a,disease
R509	T3188	T3186	pobj	disease,from
R510	T3189	T3188	amod	stable,disease
R511	T3190	T3189	cc	or,stable
R512	T3191	T3189	conj	subclinical,stable
R513	T3192	T3188	amod	atherosclerotic,disease
R514	T3193	T3175	cc	and,is
R515	T3194	T3175	conj	leads,is
R516	T3195	T3194	prep	to,leads
R517	T3196	T3197	amod	acute,infarction
R519	T3198	T3197	amod	myocardial,infarction
R520	T3199	T3197	punct	", ",infarction
R521	T3200	T3201	amod	ischemic,stroke
R522	T3201	T3197	conj	stroke,infarction
R523	T3202	T3201	cc	or,stroke
R524	T3203	T3204	amod	peripheral,arterial
R525	T3204	T3205	amod	arterial,occlusion
R526	T3205	T3201	conj	occlusion,stroke
R527	T3206	T3175	punct	.,is
R528	T3208	T3209	amod	Arterial,thrombosis
R529	T3209	T3212	nsubj	thrombosis,are
R530	T3210	T3208	cc	and,Arterial
R531	T3211	T3208	conj	venous,Arterial
R532	T3213	T3214	amod	complex,responses
R533	T3214	T3212	attr	responses,are
R534	T3215	T3212	cc	and,are
R535	T3216	T3217	auxpass	are,influenced
R536	T3217	T3212	conj	influenced,are
R537	T3218	T3217	agent	by,influenced
R538	T3219	T3220	amod	multiple,factors
R539	T3220	T3218	pobj	factors,by
R540	T3221	T3220	amod	genetic,factors
R541	T3222	T3221	cc	and,genetic
R542	T3223	T3221	conj	environmental,genetic
R543	T3224	T3225	punct	[,2
R544	T3225	T3217	parataxis	2,influenced
R545	T3226	T3227	punct	-,5
R546	T3227	T3225	prep	5,2
R547	T3228	T3225	punct	],2
R548	T3229	T3212	punct	.,are
R549	T3231	T3232	nsubjpass	Polymorphisms,implicated
R550	T3233	T3231	cc	and,Polymorphisms
R551	T3234	T3231	conj	mutations,Polymorphisms
R552	T3235	T3231	prep	in,Polymorphisms
R553	T3236	T3237	compound	coagulation,factors
R554	T3237	T3235	pobj	factors,in
R555	T3238	T3237	punct	", ",factors
R556	T3239	T3240	amod	fibrinolytic,factors
R557	T3240	T3237	conj	factors,factors
R558	T3241	T3240	punct	", ",factors
R559	T3242	T3243	compound	platelet,surface
R560	T3243	T3244	compound	surface,receptors
R561	T3244	T3240	conj	receptors,factors
R562	T3245	T3244	punct	", ",receptors
R563	T3246	T3247	compound	methylenetetrahydrofalate,reductase
R564	T3247	T3244	conj	reductase,receptors
R565	T3248	T3247	punct	", ",reductase
R566	T3249	T3250	amod	endothelial,synthase
R567	T3250	T3247	conj	synthase,reductase
R568	T3251	T3252	amod	nitric,oxide
R569	T3252	T3250	compound	oxide,synthase
R570	T3253	T3250	punct	", ",synthase
R571	T3254	T3250	cc	and,synthase
R572	T3255	T3256	amod	antioxidant,enzymes
R573	T3256	T3250	conj	enzymes,synthase
R574	T3257	T3232	aux	have,implicated
R575	T3258	T3232	auxpass	been,implicated
R576	T3259	T3232	prep	as,implicated
R577	T3260	T3261	amod	genetic,determinants
R578	T3261	T3259	pobj	determinants,as
R579	T3262	T3261	prep	of,determinants
R580	T3263	T3262	pobj	susceptibility,of
R581	T3264	T3263	prep	to,susceptibility
R582	T3265	T3264	pobj	thrombosis,to
R583	T3266	T3267	punct	[,7
R584	T3267	T3232	parataxis	7,implicated
R585	T3268	T3267	nummod	6,7
R586	T3269	T3267	punct	",",7
R587	T3270	T3267	punct	],7
R588	T3271	T3232	punct	.,implicated
R589	T3273	T3274	amod	Great,strides
R590	T3274	T3275	nsubjpass	strides,made
R591	T3276	T3275	aux	have,made
R592	T3277	T3275	auxpass	been,made
R593	T3278	T3275	prep	in,made
R594	T3279	T3280	det	the,diagnosis
R595	T3280	T3278	pobj	diagnosis,in
R596	T3281	T3280	cc	and,diagnosis
R597	T3282	T3280	conj	treatment,diagnosis
R598	T3283	T3280	prep	of,diagnosis
R599	T3284	T3283	pobj	thrombosis,of
R600	T3285	T3275	prep	in,made
R601	T3286	T3287	det	the,decade
R603	T3288	T3287	amod	last,decade
R604	T3289	T3275	punct	.,made
R605	T3291	T3292	advmod	However,lagged
R606	T3293	T3292	punct	", ",lagged
R607	T3294	T3292	nsubj	strategies,lagged
R608	T3295	T3296	aux	to,prevent
R609	T3296	T3294	advcl	prevent,strategies
R610	T3297	T3296	dobj	thrombosis,prevent
R611	T3298	T3292	aux	have,lagged
R612	T3299	T3300	advmod	far,behind
R613	T3300	T3292	advmod	behind,lagged
R614	T3301	T3292	prep	due,lagged
R615	T3302	T3301	punct	", ",due
R616	T3303	T3301	prep	in,due
R617	T3304	T3303	amod	part,in
R618	T3305	T3301	punct	", ",due
R619	T3306	T3301	pcomp	to,due
R620	T3307	T3308	det	the,contribution
R621	T3308	T3301	pobj	contribution,due
R622	T3309	T3308	prep	of,contribution
R623	T3310	T3311	amod	multiple,factors
R624	T3311	T3309	pobj	factors,of
R625	T3312	T3310	punct	", ",multiple
R626	T3313	T3310	cc	and,multiple
R627	T3314	T3315	advmod	as,yet
R628	T3315	T3316	advmod	yet,undefined
R629	T3316	T3310	conj	undefined,multiple
R630	T3317	T3311	punct	", ",factors
R631	T3318	T3311	amod	genetic,factors
R632	T3319	T3320	dep	that,lead
R633	T3320	T3311	relcl	lead,factors
R634	T3321	T3320	prep	to,lead
R635	T3322	T3323	amod	thrombotic,risk
R636	T3323	T3321	pobj	risk,to
R637	T3324	T3292	punct	.,lagged
R638	T3326	T3327	advmod	Moreover,remains
R639	T3328	T3327	punct	", ",remains
R640	T3329	T3327	nsubj	it,remains
R641	T3330	T3327	oprd	unclear,remains
R642	T3331	T3332	advmod	how,influences
R643	T3332	T3327	ccomp	influences,remains
R644	T3333	T3334	amod	genetic,background
R645	T3334	T3332	nsubj	background,influences
R646	T3335	T3336	det	the,function
R647	T3336	T3332	dobj	function,influences
R648	T3337	T3336	prep	of,function
R649	T3338	T3337	pobj	molecules,of
R650	T3339	T3338	cc	and,molecules
R651	T3340	T3338	conj	pathways,molecules
R652	T3341	T3338	acl	known,molecules
R653	T3342	T3343	aux	to,regulate
R654	T3343	T3341	xcomp	regulate,known
R655	T3344	T3345	compound	thrombus,formation
R656	T3345	T3343	dobj	formation,regulate
R657	T3346	T3345	cc	and,formation
R658	T3347	T3345	conj	lysis,formation
R659	T3348	T3332	cc	and,influences
R660	T3349	T3332	punct	", ",influences
R661	T3350	T3351	advmod	thereby,contributes
R663	T3352	T3351	punct	", ",contributes
R664	T3353	T3351	prep	to,contributes
R665	T3354	T3355	det	the,risk
R666	T3355	T3353	pobj	risk,to
R667	T3356	T3355	prep	of,risk
R668	T3357	T3358	amod	thrombotic,disease
R669	T3358	T3356	pobj	disease,of
R670	T3359	T3327	punct	.,remains
R671	T3465	T3462	punct	;,10
R672	T3466	T3467	compound	A,J
R673	T3467	T3469	nsubj	J,susceptible
R674	T3468	T3467	punct	/,J
R675	T3469	T3462	amod	susceptible,10
R676	T3470	T3462	punct	),10
R677	T3471	T3462	punct	[,10
R678	T3472	T3462	punct	],10
R679	T3473	T3402	punct	.,have
R680	T3475	T3476	det	These,conditions
R681	T3476	T3477	nsubj	conditions,are
R682	T3478	T3477	acomp	predisposing,are
R683	T3479	T3478	prep	to,predisposing
R684	T3480	T3479	pobj	thrombosis,to
R685	T3481	T3482	advmod	per,se
R686	T3361	T3362	nsubjpass	Many,classified
R687	T3482	T3477	advmod	se,are
R688	T3483	T3477	punct	", ",are
R689	T3363	T3361	prep	of,Many
R690	T3484	T3477	cc	but,are
R691	T3364	T3365	det	the,strains
R692	T3365	T3363	pobj	strains,of
R693	T3366	T3365	amod	available,strains
R694	T3485	T3486	det	these,mice
R695	T3367	T3368	amod	inbred,mouse
R696	T3368	T3365	compound	mouse,strains
R697	T3486	T3487	nsubjpass	mice,evaluated
R698	T3369	T3365	punct	", ",strains
R699	T3370	T3371	amod	such,as
R700	T3371	T3365	prep	as,strains
R701	T3487	T3477	conj	evaluated,are
R702	T3372	T3373	compound	C57BL,6J
R703	T3373	T3371	pobj	6J,as
R704	T3374	T3373	punct	/,6J
R705	T3488	T3487	aux	have,evaluated
R706	T3375	T3373	punct	(,6J
R707	T3376	T3373	appos	B6,6J
R708	T3377	T3373	punct	),6J
R709	T3489	T3487	neg	not,evaluated
R710	T3378	T3373	cc	and,6J
R711	T3379	T3380	compound	A,J
R712	T3380	T3373	conj	J,6J
R713	T3490	T3487	auxpass	been,evaluated
R714	T3381	T3380	punct	/,J
R715	T3382	T3362	punct	", ",classified
R716	T3383	T3362	aux	have,classified
R717	T3384	T3362	auxpass	been,classified
R718	T3385	T3362	prep	as,classified
R719	T3386	T3385	amod	resistant,as
R720	T3491	T3487	advmod	systematically,evaluated
R721	T3387	T3386	cc	or,resistant
R722	T3388	T3386	conj	susceptible,resistant
R723	T3389	T3388	prep	to,susceptible
R724	T3492	T3487	prep	for,evaluated
R725	T3390	T3391	amod	particular,diseases
R726	T3391	T3389	pobj	diseases,to
R727	T3493	T3492	pobj	thrombosis,for
R728	T3392	T3391	amod	complex,diseases
R729	T3393	T3394	punct	(,Table
R730	T3394	T3362	parataxis	Table,classified
R731	T3494	T3487	punct	.,evaluated
R732	T3395	T3394	nummod	1,Table
R733	T3396	T3394	punct	),Table
R734	T3397	T3362	punct	.,classified
R735	T3496	T3497	compound	Clot,formation
R736	T3399	T3400	det	These,strains
R737	T3400	T3402	nsubj	strains,have
R738	T3401	T3400	nummod	two,strains
R739	T3497	T3498	nsubj	formation,requires
R740	T3403	T3404	amod	diverse,responses
R741	T3404	T3402	dobj	responses,have
R742	T3405	T3404	prep	to,responses
R743	T3499	T3497	cc	and,formation
R744	T3406	T3407	npadvmod	diet,induced
R745	T3407	T3409	amod	induced,obesity
R746	T3408	T3407	punct	-,induced
R747	T3409	T3405	pobj	obesity,to
R748	T3500	T3497	conj	lysis,formation
R749	T3410	T3411	punct	[,8
R750	T3411	T3409	parataxis	8,obesity
R751	T3412	T3411	punct	],8
R752	T3501	T3497	punct	", ",formation
R753	T3413	T3414	punct	(,resistant
R754	T3414	T3409	parataxis	resistant,obesity
R755	T3415	T3416	nsubj	B6,susceptible
R756	T3502	T3503	dep	which,determine
R757	T3416	T3414	amod	susceptible,resistant
R758	T3417	T3414	punct	;,resistant
R759	T3418	T3419	compound	A,J
R760	T3503	T3497	relcl	determine,formation
R761	T3419	T3414	nsubj	J,resistant
R762	T3420	T3419	punct	/,J
R763	T3421	T3414	punct	),resistant
R764	T3504	T3503	advmod	ultimately,determine
R765	T3422	T3409	punct	", ",obesity
R766	T3423	T3424	npadvmod	diet,induced
R767	T3424	T3426	amod	induced,atherosclerosis
R768	T3425	T3424	punct	-,induced
R769	T3505	T3503	dobj	thrombosis,determine
R770	T3506	T3498	punct	", ",requires
R771	T3426	T3409	conj	atherosclerosis,obesity
R772	T3427	T3428	punct	(,resistant
R773	T3507	T3508	compound	platelet,aggregation
R774	T3428	T3426	parataxis	resistant,atherosclerosis
R775	T3429	T3430	nsubj	B6,susceptible
R776	T3508	T3498	dobj	aggregation,requires
R777	T3430	T3428	amod	susceptible,resistant
R778	T3431	T3428	punct	;,resistant
R779	T3432	T3433	compound	A,J
R780	T3509	T3508	punct	", ",aggregation
R781	T3433	T3428	nsubj	J,resistant
R782	T3434	T3433	punct	/,J
R783	T3510	T3508	conj	coagulation,aggregation
R784	T3435	T3428	punct	),resistant
R785	T3436	T3437	punct	[,9
R787	T3437	T3426	parataxis	9,atherosclerosis
R788	T3438	T3437	punct	],9
R789	T3439	T3426	punct	", ",atherosclerosis
R791	T3440	T3441	amod	arterial,ligation
R792	T3441	T3442	npadvmod	ligation,induced
R793	T3442	T3444	amod	induced,hyperplasia
R794	T3443	T3442	punct	-,induced
R796	T3444	T3426	conj	hyperplasia,atherosclerosis
R797	T3445	T3444	amod	neointimal,hyperplasia
R799	T3446	T3447	punct	(,resistant
R800	T3447	T3444	parataxis	resistant,hyperplasia
R801	T3448	T3449	nsubj	B6,resistant
R803	T3449	T3447	amod	resistant,resistant
R804	T3450	T3447	punct	;,resistant
R806	T3451	T3452	compound	A,J
R807	T3452	T3447	nsubj	J,resistant
R808	T3453	T3452	punct	/,J
R809	T3454	T3447	punct	),resistant
R810	T3455	T3444	punct	", ",hyperplasia
R812	T3456	T3444	cc	and,hyperplasia
R813	T3457	T3458	npadvmod	ligation,induced
R814	T3458	T3459	amod	induced,remodeling
R815	T3459	T3444	conj	remodeling,hyperplasia
R817	T3460	T3459	compound	vessel,remodeling
R818	T3461	T3462	punct	(,10
R820	T3462	T3459	parataxis	10,remodeling
R821	T3463	T3464	nsubj	B6,resistant
R822	T3464	T3462	amod	resistant,10
R854	T3592	T3586	compound	breeding,program
R855	T3593	T3594	advmod	where,backcrossed
R856	T3594	T3586	relcl	backcrossed,program
R858	T3595	T3596	det	the,progeny
R859	T3596	T3594	nsubjpass	progeny,backcrossed
R860	T3597	T3596	prep	of,progeny
R861	T3598	T3599	det	a,cross
R863	T3599	T3597	pobj	cross,of
R864	T3600	T3599	nmod	B6,cross
R866	T3601	T3600	punct	×,B6
R867	T3602	T3603	compound	A,J
R868	T3603	T3600	appos	J,B6
R869	T3604	T3603	punct	/,J
R871	T3605	T3594	auxpass	were,backcrossed
R872	T3606	T3594	advmod	successively,backcrossed
R873	T3607	T3594	prep	to,backcrossed
R874	T3608	T3609	det	the,mice
R875	T3609	T3607	pobj	mice,to
R876	T3610	T3609	compound	B6,mice
R878	T3611	T3572	punct	.,generated
R879	T3613	T3614	amod	Genetic,markers
R881	T3614	T3615	nsubjpass	markers,used
R883	T3616	T3615	auxpass	were,used
R884	T3617	T3618	aux	to,identify
R885	T3618	T3615	advcl	identify,used
R886	T3619	T3618	dobj	homozygosity,identify
R888	T3620	T3619	prep	in,homozygosity
R889	T3621	T3622	det	the,B6
R890	T3543	T3533	auxpass	be,identified
R891	T3544	T3533	prep	by,identified
R892	T3545	T3544	pcomp	associating,by
R893	T3546	T3547	det	the,phenotype
R894	T3622	T3620	pobj	B6,in
R895	T3623	T3622	nmod	background,B6
R896	T3624	T3622	punct	(,B6
R897	T3547	T3545	dobj	phenotype,associating
R898	T3625	T3622	punct	),B6
R899	T3626	T3622	cc	and,B6
R900	T3548	T3545	prep	with,associating
R901	T3627	T3628	det	the,J
R902	T3628	T3632	compound	J,chromosome
R903	T3629	T3628	amod	individual,J
R904	T3549	T3550	det	a,location
R905	T3630	T3628	compound	A,J
R906	T3631	T3628	punct	/,J
R907	T3632	T3622	conj	chromosome,B6
R908	T3550	T3548	pobj	location,with
R909	T3633	T3615	punct	.,used
R910	T3551	T3550	punct	(,location
R911	T3552	T3550	nmod	s,location
R912	T3635	T3636	det	These,strains
R913	T3553	T3550	punct	),location
R914	T3636	T3637	nsubj	strains,have
R915	T3554	T3550	prep	on,location
R916	T3638	T3639	nummod	one,chromosome
R917	T3639	T3637	dobj	chromosome,have
R918	T3640	T3639	prep	from,chromosome
R919	T3555	T3556	det	a,chromosome
R920	T3641	T3642	compound	A,J
R921	T3642	T3644	compound	J,mice
R922	T3643	T3642	punct	/,J
R923	T3556	T3554	pobj	chromosome,on
R924	T3644	T3640	pobj	mice,from
R925	T3645	T3637	prep	in,have
R926	T3646	T3647	det	a,background
R927	T3647	T3645	pobj	background,in
R928	T3648	T3647	compound	B6,background
R929	T3557	T3556	amod	specific,chromosome
R930	T3649	T3637	punct	.,have
R931	T3651	T3652	nsubj	This,allows
R932	T3558	T3550	punct	", ",location
R933	T3653	T3654	det	the,identification
R934	T3654	T3652	dobj	identification,allows
R935	T3559	T3560	det	a,locus
R936	T3655	T3654	prep	of,identification
R937	T3656	T3657	det	a,trait
R938	T3657	T3655	pobj	trait,of
R939	T3560	T3550	appos	locus,location
R940	T3658	T3657	prep	in,trait
R941	T3659	T3660	nummod	one,CSS
R942	T3561	T3560	amod	quantitative,locus
R943	T3660	T3658	pobj	CSS,in
R944	T3661	T3659	cc	or,one
R945	T3662	T3659	conj	more,one
R946	T3562	T3560	compound	trait,locus
R947	T3663	T3652	cc	and,allows
R948	T3664	T3652	conj	implies,allows
R949	T3563	T3560	punct	(,locus
R950	T3665	T3666	mark	that,resides
R951	T3666	T3664	ccomp	resides,implies
R952	T3667	T3668	advmod	at,one
R953	T3564	T3560	appos	QTL,locus
R954	T3668	T3670	nummod	one,QTL
R955	T3669	T3668	advmod	least,one
R956	T3670	T3666	nsubj	QTL,resides
R957	T3565	T3533	punct	),identified
R958	T3671	T3666	prep	on,resides
R959	T3672	T3673	det	this,chromosome
R960	T3673	T3671	pobj	chromosome,on
R961	T3566	T3533	punct	.,identified
R962	T3674	T3652	punct	.,allows
R963	T3676	T3677	nsubj	Use,requires
R964	T3728	T3714	punct	.,simplify
R965	T3678	T3676	prep	of,Use
R966	T3679	T3680	det	this,panel
R967	T3680	T3678	pobj	panel,of
R968	T3730	T3731	amod	Several,studies
R969	T3681	T3682	amod	fewer,mice
R970	T3682	T3677	dobj	mice,requires
R971	T3683	T3684	aux	to,determine
R972	T3684	T3677	advcl	determine,requires
R973	T3685	T3686	det	the,QTL
R974	T3731	T3732	nsubjpass	studies,reported
R975	T3686	T3684	dobj	QTL,determine
R976	T3687	T3688	mark	than,does
R977	T3688	T3677	advcl	does,requires
R978	T3689	T3690	det	a,scan
R979	T3690	T3688	nsubj	scan,does
R980	T3691	T3692	npadvmod	genome,wide
R981	T3692	T3690	amod	wide,scan
R982	T3733	T3731	prep	of,studies
R983	T3693	T3692	punct	-,wide
R984	T3694	T3677	punct	.,requires
R985	T3696	T3697	det	Another,advantage
R986	T3734	T3735	det	this,panel
R987	T3697	T3698	nsubj	advantage,is
R988	T3699	T3700	det	the,ability
R989	T3735	T3733	pobj	panel,of
R990	T3700	T3698	attr	ability,is
R991	T3701	T3700	prep	for,ability
R992	T3702	T3701	pobj	detection,for
R993	T3703	T3702	prep	of,detection
R994	T3736	T3735	compound	CSS,panel
R995	T3704	T3703	pobj	QTL,of
R996	T3705	T3702	prep	in,detection
R997	T3706	T3707	det	the,presence
R998	T3737	T3735	punct	", ",panel
R999	T3707	T3705	pobj	presence,in
R1000	T3708	T3707	prep	of,presence
R1001	T3709	T3710	amod	other,QTL
R1002	T3738	T3739	compound	B6,19
R1003	T3710	T3708	pobj	QTL,of
R1004	T3711	T3698	punct	.,is
R1005	T3739	T3735	appos	19,panel
R1006	T3713	T3714	prep	In,simplify
R1007	T3740	T3739	compound	Chr1,19
R1008	T3715	T3713	pobj	addition,In
R1009	T3716	T3714	punct	", ",simplify
R1010	T3717	T3718	amod	initial,screens
R1011	T3718	T3714	nsubj	screens,simplify
R1012	T3741	T3739	punct	-,19
R1013	T3719	T3718	prep	with,screens
R1014	T3720	T3721	det	the,CSS
R1015	T3742	T3739	punct	", ",19
R1016	T3721	T3719	pobj	CSS,with
R1017	T3722	T3723	det	the,mapping
R1018	T3743	T3739	appos	X,19
R1019	T3723	T3714	dobj	mapping,simplify
R1020	T3744	T3739	punct	", ",19
R1021	T3724	T3723	advmod	fine,mapping
R1022	T3725	T3723	punct	-,mapping
R1023	T3745	T3746	compound	YA,J
R1024	T3726	T3723	prep	of,mapping
R1025	T3727	T3726	pobj	QTL,of
R1026	T3746	T3739	appos	J,19
R1027	T3747	T3746	punct	/,J
R1028	T3748	T3732	punct	", ",reported
R1029	T3834	T3832	conj	fibrinolysis,coagulation
R1030	T3749	T3732	aux	have,reported
R1031	T3835	T3801	punct	.,was
R1032	T3750	T3732	auxpass	been,reported
R1033	T3837	T3838	det	The,results
R1034	T3838	T3839	nsubj	results,indicate
R1035	T3751	T3732	prep	for,reported
R1036	T3840	T3838	prep	of,results
R1037	T3841	T3842	det	this,study
R1038	T3752	T3751	pobj	behavior,for
R1039	T3842	T3840	pobj	study,of
R1040	T3843	T3844	mark	that,have
R1041	T3844	T3839	ccomp	have,indicate
R1042	T3753	T3754	punct	[,12
R1043	T3845	T3846	det	the,strains
R1044	T3846	T3844	nsubj	strains,have
R1045	T3754	T3752	parataxis	12,behavior
R1046	T3847	T3846	nummod	two,strains
R1047	T3848	T3846	amod	inbred,strains
R1048	T3849	T3846	punct	", ",strains
R1049	T3755	T3754	punct	],12
R1050	T3850	T3851	nmod	B6,mice
R1051	T3851	T3846	appos	mice,strains
R1052	T3852	T3850	cc	and,B6
R1053	T3756	T3752	punct	", ",behavior
R1054	T3853	T3854	compound	A,J
R1055	T3854	T3850	conj	J,B6
R1056	T3757	T3758	compound	weight,gain
R1057	T3855	T3854	punct	/,J
R1058	T3758	T3752	conj	gain,behavior
R1059	T3856	T3844	punct	", ",have
R1060	T3857	T3858	amod	diverse,phenotypes
R1061	T3858	T3844	dobj	phenotypes,have
R1062	T3859	T3858	amod	prothrombotic,phenotypes
R1063	T3759	T3760	punct	[,13
R1064	T3860	T3858	punct	", ",phenotypes
R1065	T3861	T3858	amod	unrelated,phenotypes
R1066	T3760	T3758	parataxis	13,gain
R1067	T3862	T3861	prep	to,unrelated
R1068	T3863	T3862	pobj	coagulation,to
R1069	T3864	T3863	cc	or,coagulation
R1070	T3761	T3760	punct	],13
R1071	T3865	T3866	compound	platelet,aggregation
R1072	T3866	T3863	conj	aggregation,coagulation
R1073	T3867	T3839	punct	.,indicate
R1074	T3762	T3758	punct	", ",gain
R1075	T3869	T3870	prep	In,modified
R1076	T3763	T3758	conj	sterols,gain
R1077	T3871	T3869	pobj	addition,In
R1078	T3872	T3870	punct	", ",modified
R1079	T3764	T3765	punct	[,13
R1080	T3873	T3870	prep	in,modified
R1081	T3874	T3875	det	the,CSS
R1082	T3875	T3873	pobj	CSS,in
R1083	T3876	T3870	punct	", ",modified
R1084	T3877	T3870	nsubjpass	expression,modified
R1085	T3878	T3877	prep	of,expression
R1086	T3765	T3763	parataxis	13,sterols
R1087	T3879	T3880	det	the,phenotypes
R1088	T3880	T3878	pobj	phenotypes,of
R1089	T3881	T3882	compound	A,J
R1090	T3766	T3765	punct	],13
R1091	T3882	T3880	compound	J,phenotypes
R1092	T3883	T3882	punct	/,J
R1093	T3767	T3763	punct	", ",sterols
R1094	T3884	T3880	punct	", ",phenotypes
R1095	T3885	T3886	compound	rebleeding,time
R1096	T3886	T3880	conj	time,phenotypes
R1097	T3887	T3886	cc	and,time
R1098	T3768	T3763	cc	and,sterols
R1099	T3888	T3889	amod	arterial,occlusion
R1100	T3889	T3886	conj	occlusion,time
R1101	T3769	T3770	compound	plasma,levels
R1102	T3890	T3870	punct	", ",modified
R1103	T3891	T3870	auxpass	was,modified
R1104	T3892	T3870	prep	in,modified
R1105	T3770	T3763	conj	levels,sterols
R1106	T3771	T3772	compound	amino,acids
R1107	T3893	T3894	det	the,background
R1108	T3772	T3770	compound	acids,levels
R1109	T3894	T3892	pobj	background,in
R1110	T3895	T3894	compound	B6,background
R1111	T3773	T3774	punct	[,14
R1112	T3896	T3870	punct	", ",modified
R1113	T3897	T3870	cc	and,modified
R1114	T3774	T3770	parataxis	14,levels
R1115	T3898	T3870	conj	suggested,modified
R1116	T3899	T3900	mark	that,occurred
R1117	T3900	T3898	ccomp	occurred,suggested
R1118	T3775	T3774	nummod	13,14
R1119	T3901	T3900	nsubj	interactions,occurred
R1120	T3902	T3900	prep	among,occurred
R1121	T3776	T3774	punct	",",14
R1122	T3903	T3904	det	the,QTL
R1123	T3904	T3902	pobj	QTL,among
R1124	T3905	T3906	compound	A,J
R1125	T3777	T3774	punct	],14
R1126	T3906	T3904	compound	J,QTL
R1127	T3907	T3906	punct	/,J
R1128	T3778	T3732	punct	", ",reported
R1129	T3908	T3870	punct	.,modified
R1130	T3910	T3911	advmod	Thus,be
R1131	T3779	T3732	cc	and,reported
R1132	T3912	T3911	punct	", ",be
R1133	T3913	T3911	nsubj	it,be
R1134	T3914	T3911	aux	should,be
R1135	T3915	T3911	acomp	possible,be
R1136	T3780	T3781	aux	have,identified
R1137	T3916	T3917	aux	to,identify
R1138	T3917	T3911	xcomp	identify,be
R1139	T3918	T3919	amod	independent,determinants
R1140	T3919	T3917	dobj	determinants,identify
R1141	T3781	T3732	conj	identified,reported
R1142	T3920	T3919	amod	genetic,determinants
R1143	T3921	T3919	prep	of,determinants
R1144	T3922	T3921	pobj	susceptibility,of
R1145	T3782	T3783	amod	many,more
R1146	T3923	T3922	prep	to,susceptibility
R1147	T3924	T3925	amod	pathological,haemostasis
R1148	T3783	T3784	amod	more,QTL
R1149	T3925	T3923	pobj	haemostasis,to
R1150	T3926	T3925	cc	and,haemostasis
R1151	T3927	T3925	conj	thrombosis,haemostasis
R1152	T3784	T3781	dobj	QTL,identified
R1153	T3928	T3911	punct	.,be
R1154	T3785	T3784	prep	than,QTL
R1155	T3786	T3785	pobj	studies,than
R1156	T3787	T3786	prep	of,studies
R1157	T3788	T3789	det	the,traits
R1158	T3789	T3787	pobj	traits,of
R1159	T3790	T3789	amod	same,traits
R1160	T3791	T3786	acl	using,studies
R1161	T3792	T3793	det	a,scan
R1162	T3793	T3791	dobj	scan,using
R1163	T3794	T3795	npadvmod	genome,wide
R1164	T3795	T3793	amod	wide,scan
R1165	T3796	T3795	punct	-,wide
R1166	T3797	T3732	punct	.,reported
R1167	T3799	T3800	det	The,purpose
R1168	T3800	T3801	nsubj	purpose,was
R1169	T3802	T3800	prep	of,purpose
R1170	T3803	T3804	det	this,study
R1171	T3804	T3802	pobj	study,of
R1172	T3805	T3806	aux	to,evaluate
R1173	T3806	T3801	xcomp	evaluate,was
R1174	T3807	T3808	det	the,strains
R1175	T3808	T3806	dobj	strains,evaluate
R1176	T3809	T3808	nummod	two,strains
R1177	T3810	T3808	amod	inbred,strains
R1178	T3811	T3808	prep	of,strains
R1179	T3812	T3811	pobj	mice,of
R1180	T3813	T3806	prep	for,evaluate
R1181	T3814	T3815	amod	prothrombotic,risk
R1182	T3815	T3813	pobj	risk,for
R1183	T3816	T3806	punct	", ",evaluate
R1184	T3817	T3806	advcl	utilizing,evaluate
R1185	T3818	T3819	det	a,model
R1186	T3819	T3817	dobj	model,utilizing
R1187	T3820	T3821	amod	ferric,chloride
R1188	T3821	T3819	nmod	chloride,model
R1189	T3822	T3823	amod	vascular,injury
R1190	T3823	T3819	compound	injury,model
R1191	T3824	T3819	punct	", ",model
R1192	T3825	T3826	compound	tail,bleeding
R1193	T3826	T3827	compound	bleeding,assay
R1194	T3827	T3819	conj	assay,model
R1195	T3828	T3827	punct	", ",assay
R1196	T3829	T3827	cc	and,assay
R1197	T3830	T3827	conj	measures,assay
R1198	T3831	T3830	prep	of,measures
R1199	T3832	T3831	pobj	coagulation,of
R1200	T3833	T3832	cc	and,coagulation
R1205	T4566	T4567	det	The,strains
R1206	T4567	T4569	nsubjpass	strains,obtained
R1207	T4568	T4567	amod	inbred,strains
R1208	T4570	T4567	punct	", ",strains
R1209	T4571	T4567	conj	B6,strains
R1210	T4572	T4573	punct	(,#
R1211	T4573	T4571	parataxis	#,B6
R1212	T4574	T4573	nummod	000664,#
R1213	T4575	T4573	punct	),#
R1214	T4576	T4571	punct	", ",B6
R1215	T4577	T4571	conj	Lepob,B6
R1216	T4578	T4579	punct	(,#
R1217	T4579	T4577	parataxis	#,Lepob
R1218	T4580	T4579	nummod	000632,#
R1219	T4581	T4579	punct	),#
R1220	T4582	T4577	punct	", ",Lepob
R1221	T4583	T4584	compound	A,J
R1222	T4584	T4577	conj	J,Lepob
R1223	T4585	T4584	punct	/,J
R1224	T4586	T4587	punct	(,#
R1225	T4587	T4584	parataxis	#,J
R1226	T4588	T4587	nummod	000646,#
R1227	T4589	T4587	punct	),#
R1228	T4590	T4584	cc	and,J
R1229	T4591	T4592	npadvmod	gene,targeted
R1230	T4592	T4594	amod	targeted,mice
R1231	T4593	T4592	punct	-,targeted
R1232	T4594	T4584	conj	mice,J
R1233	T4595	T4596	nmod	plasminogen,inhibitor
R1234	T4596	T4601	npadvmod	inhibitor,deficient
R1235	T4597	T4595	punct	(,plasminogen
R1236	T4598	T4595	appos	Plg,plasminogen
R1237	T4599	T4596	punct	),inhibitor
R1238	T4600	T4596	compound	activator,inhibitor
R1239	T4601	T4594	amod	deficient,mice
R1240	T4602	T4594	punct	(,mice
R1241	T4603	T4604	nmod	PAI,mice
R1242	T4604	T4594	appos	mice,mice
R1243	T4605	T4603	punct	-,PAI
R1244	T4606	T4603	nummod	1,PAI
R1245	T4607	T4603	punct	-,PAI
R1246	T4608	T4603	punct	/,PAI
R1247	T4609	T4603	punct	-,PAI
R1248	T4610	T4603	punct	),PAI
R1249	T4611	T4612	punct	(,#
R1250	T4612	T4603	parataxis	#,PAI
R1251	T4613	T4612	nummod	002507,#
R1252	T4614	T4612	punct	),#
R1253	T4615	T4616	punct	[,15
R1254	T4616	T4603	parataxis	15,PAI
R1255	T4617	T4616	punct	],15
R1256	T4618	T4594	prep	in,mice
R1257	T4619	T4620	det	a,background
R1258	T4620	T4618	pobj	background,in
R1259	T4621	T4620	compound	B6,background
R1260	T4622	T4569	auxpass	were,obtained
R1261	T4623	T4569	prep	from,obtained
R1262	T4624	T4625	compound	Jackson,Laboratory
R1263	T4625	T4623	pobj	Laboratory,from
R1264	T4626	T4625	punct	(,Laboratory
R1265	T4627	T4628	compound	Bar,Harbor
R1266	T4628	T4625	npadvmod	Harbor,Laboratory
R1267	T4629	T4625	punct	", ",Laboratory
R1268	T4630	T4625	npadvmod	Maine,Laboratory
R1269	T4631	T4569	punct	),obtained
R1270	T4632	T4569	prep	at,obtained
R1271	T4633	T4634	nummod	6,wks
R1272	T4634	T4632	pobj	wks,at
R1273	T4635	T4634	punct	-,wks
R1274	T4636	T4634	prep	of,wks
R1275	T4637	T4636	punct	-,of
R1276	T4638	T4636	pobj	age,of
R1277	T4639	T4569	punct	.,obtained
R1278	T4641	T4642	det	The,mice
R1279	T4642	T4647	nsubjpass	mice,generated
R1280	T4643	T4642	nmod	Plg,mice
R1281	T4644	T4643	punct	-,Plg
R1282	T4645	T4643	punct	/,Plg
R1283	T4646	T4643	punct	-,Plg
R1284	T4648	T4647	auxpass	were,generated
R1285	T4649	T4650	mark	as,described
R1286	T4650	T4647	advcl	described,generated
R1287	T4651	T4650	advmod	previously,described
R1288	T4652	T4653	punct	[,16
R1289	T4653	T4650	parataxis	16,described
R1290	T4654	T4653	punct	],16
R1291	T4655	T4647	cc	and,generated
R1292	T4656	T4647	conj	maintained,generated
R1293	T4657	T4656	prep	in,maintained
R1294	T4658	T4659	det	the,background
R1295	T4659	T4657	pobj	background,in
R1296	T4660	T4659	compound	B6,background
R1297	T4661	T4656	punct	", ",maintained
R1298	T4662	T4656	conj	generated,maintained
R1299	T4663	T4662	prep	by,generated
R1300	T4664	T4663	pcomp	crossing,by
R1301	T4665	T4664	dobj	mice,crossing
R1302	T4666	T4665	prep	from,mice
R1303	T4667	T4668	det	the,background
R1304	T4668	T4666	pobj	background,from
R1305	T4669	T4668	amod	original,background
R1306	T4670	T4668	amod	mixed,background
R1307	T4671	T4668	punct	(,background
R1308	T4672	T4668	nmod	B6,background
R1309	T4673	T4672	punct	:,B6
R1310	T4674	T4672	nummod	129,B6
R1311	T4675	T4668	punct	),background
R1312	T4676	T4664	prep	for,crossing
R1313	T4677	T4678	nummod	eight,generations
R1314	T4678	T4676	pobj	generations,for
R1315	T4679	T4664	prep	with,crossing
R1316	T4680	T4681	compound	B6,mice
R1317	T4681	T4679	pobj	mice,with
R1318	T4682	T4647	punct	.,generated
R1319	T4684	T4685	det	The,mice
R1320	T4685	T4690	nsubj	mice,reproduce
R1321	T4686	T4685	nmod	Plg,mice
R1322	T4687	T4686	punct	-,Plg
R1323	T4688	T4686	punct	/,Plg
R1324	T4689	T4686	punct	-,Plg
R1325	T4691	T4690	aux	do,reproduce
R1326	T4692	T4690	neg	not,reproduce
R1327	T4693	T4690	advmod	well,reproduce
R1328	T4694	T4690	cc	and,reproduce
R1329	T4695	T4696	nmod	Plg,pairs
R1330	T4696	T4698	nsubjpass	pairs,used
R1331	T4697	T4696	amod	heterozygous,pairs
R1332	T4698	T4690	conj	used,reproduce
R1333	T4699	T4698	auxpass	were,used
R1334	T4700	T4698	prep	for,used
R1335	T4701	T4700	pobj	breeding,for
R1336	T4702	T4698	punct	.,used
R1337	T4704	T4705	nsubjpass	Genotypes,determined
R1338	T4706	T4704	punct	(,Genotypes
R1339	T4707	T4704	appos	Plg,Genotypes
R1340	T4708	T4707	punct	+,Plg
R1341	T4709	T4707	punct	/,Plg
R1342	T4710	T4707	punct	+,Plg
R1343	T4711	T4707	punct	", ",Plg
R1344	T4712	T4707	appos	Plg,Plg
R1345	T4713	T4712	punct	+,Plg
R1346	T4714	T4712	punct	/,Plg
R1347	T4715	T4712	punct	-,Plg
R1348	T4716	T4707	punct	", ",Plg
R1349	T4717	T4707	appos	Plg,Plg
R1350	T4718	T4717	punct	-,Plg
R1351	T4719	T4717	punct	/,Plg
R1352	T4720	T4717	punct	-,Plg
R1353	T4721	T4704	punct	),Genotypes
R1354	T4722	T4704	prep	of,Genotypes
R1355	T4723	T4724	det	the,offspring
R1356	T4724	T4722	pobj	offspring,of
R1357	T4725	T4705	auxpass	were,determined
R1358	T4726	T4705	prep	by,determined
R1359	T4727	T4728	det	a,assay
R1360	T4728	T4726	pobj	assay,by
R1361	T4729	T4728	compound	PCR,assay
R1362	T4730	T4728	prep	at,assay
R1363	T4731	T4732	quantmod	3,4
R1364	T4732	T4734	nummod	4,weeks
R1365	T4733	T4732	punct	–,4
R1366	T4734	T4730	pobj	weeks,at
R1367	T4735	T4734	punct	-,weeks
R1368	T4736	T4734	prep	of,weeks
R1369	T4737	T4736	punct	-,of
R1370	T4738	T4736	pobj	age,of
R1371	T4739	T4728	prep	from,assay
R1372	T4740	T4741	det	an,punch
R1373	T4741	T4739	pobj	punch,from
R1374	T4742	T4741	compound	ear,punch
R1375	T4743	T4744	punct	[,17
R1376	T4744	T4705	parataxis	17,determined
R1377	T4745	T4744	punct	],17
R1378	T4746	T4705	punct	.,determined
R1379	T4748	T4749	compound	Breeding,pairs
R1380	T4749	T4750	nsubjpass	pairs,transferred
R1381	T4751	T4749	prep	of,pairs
R1382	T4752	T4753	det	the,mice
R1383	T4753	T4751	pobj	mice,of
R1384	T4754	T4753	compound	CSS,mice
R1385	T4755	T4750	auxpass	were,transferred
R1386	T4756	T4750	prep	from,transferred
R1387	T4757	T4758	compound	Dr.,Nadeau
R1388	T4758	T4759	poss	Nadeau,laboratory
R1389	T4759	T4756	pobj	laboratory,from
R1390	T4760	T4758	case	's,Nadeau
R1391	T4761	T4750	punct	.,transferred
R1392	T4763	T4764	det	All,mice
R1393	T4764	T4765	nsubjpass	mice,housed
R1394	T4766	T4765	auxpass	were,housed
R1395	T4767	T4765	cc	and,housed
R1396	T4768	T4765	conj	bred,housed
R1397	T4769	T4768	prep	in,bred
R1398	T4770	T4771	det	the,Unit
R1399	T4771	T4769	pobj	Unit,in
R1400	T4772	T4771	compound	Biological,Unit
R1401	T4773	T4771	compound	Resource,Unit
R1402	T4774	T4771	prep	at,Unit
R1403	T4775	T4776	det	the,Foundation
R1404	T4776	T4774	pobj	Foundation,at
R1405	T4777	T4776	compound	Cleveland,Foundation
R1406	T4778	T4776	compound	Clinic,Foundation
R1407	T4779	T4776	punct	(,Foundation
R1408	T4780	T4776	appos	CCF,Foundation
R1409	T4781	T4765	punct	),housed
R1410	T4782	T4765	punct	.,housed
R1411	T4784	T4785	nsubjpass	Mice,housed
R1412	T4786	T4785	auxpass	were,housed
R1413	T4787	T4785	prep	in,housed
R1414	T4788	T4789	amod	sterilized,cages
R1415	T4789	T4787	pobj	cages,in
R1416	T4790	T4789	compound	isolator,cages
R1417	T4791	T4785	punct	", ",housed
R1418	T4792	T4785	dep	maintained,housed
R1419	T4793	T4792	prep	on,maintained
R1420	T4794	T4795	det	a,cycle
R1421	T4795	T4793	pobj	cycle,on
R1422	T4796	T4797	nummod	14,hr
R1423	T4797	T4798	nmod	hr,light
R1424	T4798	T4795	nmod	light,cycle
R1425	T4799	T4798	punct	/,light
R1426	T4800	T4801	nummod	10,hr
R1427	T4801	T4802	compound	hr,dark
R1428	T4802	T4798	appos	dark,light
R1429	T4803	T4785	punct	", ",housed
R1430	T4804	T4785	cc	and,housed
R1431	T4805	T4806	auxpass	were,provided
R1432	T4806	T4785	conj	provided,housed
R1433	T4807	T4808	amod	sterilized,food
R1434	T4808	T4806	dobj	food,provided
R1435	T4809	T4808	cc	and,food
R1436	T4810	T4808	conj	water,food
R1437	T4811	T4812	advmod	ad,libitum
R1438	T4812	T4806	advmod	libitum,provided
R1439	T4813	T4785	punct	.,housed
R1440	T4815	T4816	nsubjpass	Mice,fed
R1441	T4817	T4816	auxpass	were,fed
R1442	T4818	T4819	det	a,diet
R1443	T4819	T4816	dobj	diet,fed
R1444	T4820	T4819	amod	standard,diet
R1445	T4821	T4819	amod	autoclavable,diet
R1446	T4822	T4819	compound	laboratory,diet
R1447	T4823	T4819	acl	consisting,diet
R1448	T4824	T4823	prep	of,consisting
R1449	T4825	T4824	punct	: ,of
R1450	T4826	T4827	nummod	23,%
R1451	T4827	T4828	compound	%,protein
R1452	T4828	T4824	pobj	protein,of
R1453	T4829	T4828	punct	", ",protein
R1454	T4830	T4831	nummod	4.5,%
R1455	T4831	T4832	compound	%,fat
R1456	T4832	T4828	appos	fat,protein
R1457	T4833	T4828	punct	", ",protein
R1458	T4834	T4835	nummod	6,%
R1459	T4835	T4836	compound	%,fiber
R1460	T4836	T4828	appos	fiber,protein
R1461	T4837	T4828	punct	", ",protein
R1462	T4838	T4839	punct	(,Purina
R1463	T4839	T4828	parataxis	Purina,protein
R1464	T4840	T4839	punct	", ",Purina
R1465	T4841	T4842	compound	St.,Louis
R1466	T4842	T4839	npadvmod	Louis,Purina
R1467	T4843	T4839	punct	", ",Purina
R1468	T4844	T4839	npadvmod	MO,Purina
R1469	T4845	T4839	punct	),Purina
R1470	T4846	T4816	punct	", ",fed
R1471	T4847	T4816	cc	and,fed
R1472	T4848	T4816	conj	tested,fed
R1473	T4849	T4848	prep	between,tested
R1474	T4850	T4851	nummod	7,wks
R1475	T4851	T4849	pobj	wks,between
R1476	T4852	T4850	cc	and,7
R1477	T4853	T4850	conj	9,7
R1478	T4854	T4851	punct	-,wks
R1479	T4855	T4851	prep	of,wks
R1480	T4856	T4855	punct	-,of
R1481	T4857	T4855	pobj	age,of
R1482	T4858	T4816	punct	.,fed
R1483	T4860	T4861	det	All,experiments
R1484	T4861	T4863	nsubjpass	experiments,performed
R1485	T4862	T4861	compound	animal,experiments
R1486	T4864	T4863	auxpass	were,performed
R1487	T4865	T4863	prep	in,performed
R1488	T4866	T4865	pobj	accordance,in
R1489	T4867	T4866	prep	with,accordance
R1490	T4868	T4869	det	a,protocol
R1491	T4869	T4867	pobj	protocol,with
R1492	T4870	T4869	acl	approved,protocol
R1493	T4871	T4870	agent	by,approved
R1494	T4872	T4873	det	the,Committee
R1495	T4873	T4871	pobj	Committee,by
R1496	T4874	T4873	nmod	Institutional,Committee
R1497	T4875	T4876	nmod	Animal,Care
R1498	T4876	T4873	nmod	Care,Committee
R1499	T4877	T4876	cc	and,Care
R1500	T4878	T4879	compound	Research,Advisory
R1501	T4879	T4876	conj	Advisory,Care
R1502	T4880	T4873	prep	at,Committee
R1503	T4881	T4880	pobj	CCF,at
R1504	T4882	T4863	punct	.,performed
R1505	T5305	T5306	amod	Vascular,injury
R1506	T5308	T5309	aux	To,induce
R1507	T5309	T5310	advcl	induce,employed
R1508	T5311	T5312	compound	thrombosis,formation
R1509	T5312	T5309	dobj	formation,induce
R1510	T5313	T5309	prep	in,induce
R1511	T5314	T5315	det	the,artery
R1512	T5315	T5313	pobj	artery,in
R1513	T5316	T5315	compound	carotid,artery
R1514	T5317	T5310	punct	", ",employed
R1515	T5318	T5319	det	a,model
R1516	T5319	T5310	nsubjpass	model,employed
R1517	T5320	T5321	amod	ferric,chloride
R1518	T5321	T5319	nmod	chloride,model
R1519	T5322	T5321	punct	(,chloride
R1520	T5323	T5321	appos	FeCl3,chloride
R1521	T5324	T5319	punct	),model
R1522	T5325	T5319	prep	of,model
R1523	T5326	T5327	compound	vessel,injury
R1524	T5327	T5325	pobj	injury,of
R1525	T5328	T5329	punct	[,19
R1526	T5329	T5319	parataxis	19,model
R1527	T5330	T5329	nummod	18,19
R1528	T5331	T5329	punct	",",19
R1529	T5332	T5329	punct	],19
R1530	T5333	T5310	auxpass	was,employed
R1531	T5334	T5310	punct	.,employed
R1532	T5336	T5337	nsubjpass	Mice,anesthetized
R1533	T5338	T5337	auxpass	were,anesthetized
R1534	T5339	T5337	prep	with,anesthetized
R1535	T5340	T5341	compound	ketamine,xylazine
R1536	T5341	T5339	pobj	xylazine,with
R1537	T5342	T5341	punct	/,xylazine
R1538	T5343	T5344	punct	(,mg
R1539	T5344	T5341	parataxis	mg,xylazine
R1540	T5345	T5346	nummod	80,mg
R1541	T5346	T5344	dep	mg,mg
R1542	T5347	T5348	punct	/,kg
R1543	T5348	T5346	prep	kg,mg
R1544	T5349	T5344	punct	", ",mg
R1545	T5350	T5344	nummod	5,mg
R1546	T5351	T5352	punct	/,kg
R1547	T5352	T5344	prep	kg,mg
R1548	T5353	T5344	punct	),mg
R1549	T5354	T5337	punct	", ",anesthetized
R1550	T5355	T5356	det	a,incision
R1551	T5356	T5359	nsubjpass	incision,made
R1552	T5357	T5356	nmod	midline,incision
R1553	T5358	T5356	amod	cervical,incision
R1554	T5359	T5337	conj	made,anesthetized
R1555	T5360	T5359	auxpass	was,made
R1556	T5361	T5359	cc	and,made
R1557	T5362	T5363	det	the,artery
R1558	T5363	T5367	nsubj	artery,isolated
R1559	T5364	T5363	amod	left,artery
R1560	T5365	T5363	amod	common,artery
R1561	T5366	T5363	amod	carotid,artery
R1562	T5367	T5359	conj	isolated,made
R1563	T5368	T5367	prep	by,isolated
R1564	T5369	T5370	amod	blunt,dissection
R1565	T5370	T5368	pobj	dissection,by
R1566	T5371	T5367	punct	.,isolated
R1567	T5373	T5374	det	The,probe
R1568	T5374	T5376	nsubjpass	probe,placed
R1569	T5375	T5374	compound	flow,probe
R1570	T5377	T5378	punct	(,0.5PSB
R1571	T5378	T5374	parataxis	0.5PSB,probe
R1572	T5379	T5380	compound	Transonic,Systems
R1573	T5380	T5378	dep	Systems,0.5PSB
R1574	T5381	T5378	punct	", ",0.5PSB
R1575	T5382	T5378	compound	model,0.5PSB
R1576	T5383	T5378	punct	),0.5PSB
R1577	T5384	T5376	auxpass	was,placed
R1578	T5385	T5376	prep	under,placed
R1579	T5386	T5387	det	the,artery
R1580	T5387	T5385	pobj	artery,under
R1581	T5388	T5376	cc	and,placed
R1582	T5389	T5390	advmod	when,reached
R1583	T5390	T5395	advcl	reached,applied
R1584	T5391	T5392	det	a,baseline
R1585	T5392	T5390	nsubjpass	baseline,reached
R1586	T5393	T5392	amod	stable,baseline
R1587	T5394	T5390	auxpass	was,reached
R1588	T5395	T5376	conj	applied,placed
R1589	T5396	T5395	punct	", ",applied
R1590	T5397	T5398	det	a,strip
R1591	T5398	T5395	nsubjpass	strip,applied
R1592	T5399	T5400	nummod	0.5,2
R1593	T5400	T5402	nummod	2,mm
R1594	T5401	T5400	punct	×,2
R1595	T5402	T5398	compound	mm,strip
R1596	T5403	T5398	prep	of,strip
R1597	T5404	T5405	compound	filter,paper
R1598	T5405	T5403	pobj	paper,of
R1599	T5406	T5398	acl	saturated,strip
R1600	T5407	T5406	prep	with,saturated
R1601	T5408	T5409	nummod	10,%
R1602	T5409	T5410	compound	%,FeCl3
R1603	T5410	T5411	compound	FeCl3,solution
R1604	T5411	T5407	pobj	solution,with
R1605	T5412	T5395	auxpass	was,applied
R1606	T5413	T5395	prep	to,applied
R1607	T5414	T5415	det	the,surface
R1608	T5415	T5413	pobj	surface,to
R1609	T5416	T5415	prep	of,surface
R1610	T5417	T5418	det	the,artery
R1611	T5418	T5416	pobj	artery,of
R1612	T5419	T5418	amod	carotid,artery
R1613	T5420	T5395	prep	for,applied
R1614	T5421	T5422	nummod	3,min
R1615	T5422	T5420	pobj	min,for
R1616	T5423	T5395	punct	.,applied
R1617	T5425	T5426	compound	Occlusion,time
R1618	T5426	T5427	nsubjpass	time,determined
R1619	T5428	T5427	auxpass	was,determined
R1620	T5429	T5427	prep	from,determined
R1621	T5430	T5431	det	the,addition
R1622	T5431	T5429	pobj	addition,from
R1623	T5432	T5431	prep	of,addition
R1624	T5433	T5434	det	the,solution
R1625	T5434	T5432	pobj	solution,of
R1626	T5435	T5434	compound	FeCl3,solution
R1627	T5436	T5429	prep	to,from
R1628	T5437	T5438	det	the,occlusion
R1629	T5438	T5436	pobj	occlusion,to
R1630	T5439	T5438	prep	of,occlusion
R1631	T5440	T5441	det	the,artery
R1632	T5441	T5439	pobj	artery,of
R1633	T5442	T5438	punct	(,occlusion
R1634	T5443	T5444	compound	minimum,flow
R1635	T5444	T5438	appos	flow,occlusion
R1636	T5445	T5444	compound	blood,flow
R1637	T5446	T5427	punct	),determined
R1638	T5447	T5427	punct	.,determined
R1639	T5449	T5450	det	The,probe
R1640	T5450	T5452	nsubj	probe,was
R1641	T5451	T5450	compound	flow,probe
R1642	T5453	T5452	prep	in,was
R1643	T5454	T5453	pobj	place,in
R1644	T5455	T5452	prep	from,was
R1645	T5456	T5457	det	the,establishment
R1646	T5457	T5455	pobj	establishment,from
R1647	T5458	T5457	prep	of,establishment
R1648	T5459	T5460	det	the,baseline
R1649	T5460	T5458	pobj	baseline,of
R1650	T5461	T5455	prep	until,from
R1651	T5462	T5463	amod	several,min
R1652	T5463	T5464	npadvmod	min,reached
R1653	T5464	T5461	pcomp	reached,until
R1654	T5465	T5464	mark	after,reached
R1655	T5466	T5467	det	the,occlusion
R1656	T5467	T5464	nsubjpass	occlusion,reached
R1657	T5468	T5467	amod	stable,occlusion
R1658	T5469	T5464	aux	had,reached
R1659	T5470	T5464	auxpass	been,reached
R1660	T5471	T5452	cc	or,was
R1661	T5472	T5452	conj	stopped,was
R1662	T5473	T5472	prep	at,stopped
R1663	T5474	T5475	nummod	30,min
R1664	T5475	T5473	pobj	min,at
R1665	T5476	T5477	mark	if,occluded
R1666	T5477	T5472	advcl	occluded,stopped
R1667	T5478	T5477	nsubj	it,occluded
R1668	T5479	T5477	aux	had,occluded
R1669	T5480	T5477	neg	not,occluded
R1670	T5481	T5452	punct	.,was
R1671	T5483	T5484	compound	Blood,flow
R1672	T5484	T5485	nsubjpass	flow,recorded
R1673	T5486	T5485	auxpass	was,recorded
R1674	T5487	T5488	det	every,sec
R1675	T5488	T5485	npadvmod	sec,recorded
R1676	T5489	T5488	nummod	10,sec
R1677	T5490	T5491	punct	(,TS420
R1678	T5491	T5485	parataxis	TS420,recorded
R1679	T5492	T5493	compound	Transonic,Systems
R1680	T5493	T5491	dep	Systems,TS420
R1681	T5494	T5491	punct	", ",TS420
R1682	T5495	T5491	compound	model,TS420
R1683	T5496	T5491	punct	),TS420
R1684	T5497	T5485	punct	.,recorded
R1685	T5499	T5500	expl	There,was
R1686	T5501	T5502	det	no,difference
R1687	T5502	T5500	attr	difference,was
R1688	T5503	T5502	prep	in,difference
R1689	T5504	T5505	compound	body,weight
R1690	T5505	T5503	pobj	weight,in
R1691	T5506	T5500	prep	among,was
R1692	T5507	T5508	det	the,mice
R1693	T5508	T5506	pobj	mice,among
R1694	T5509	T5510	dep	that,tested
R1695	T5510	T5508	relcl	tested,mice
R1696	T5511	T5510	auxpass	were,tested
R1697	T5512	T5510	prep	in,tested
R1698	T5513	T5514	det	the,model
R1699	T5514	T5512	pobj	model,in
R1700	T5515	T5516	amod	vascular,injury
R1701	T5516	T5514	compound	injury,model
R1702	T5517	T5500	punct	.,was
R1703	T5752	T5753	nmod	Bleeding,assay
R1704	T5754	T5752	cc	and,Bleeding
R1705	T5755	T5752	conj	rebleeding,Bleeding
R1706	T5757	T5758	prep	For,anesthetized
R1707	T5758	T5766	ccomp	anesthetized,prewarmed
R1708	T5759	T5760	det	the,assay
R1709	T5760	T5757	pobj	assay,For
R1710	T5761	T5762	compound	tail,bleeding
R1711	T5762	T5760	compound	bleeding,assay
R1712	T5763	T5758	punct	", ",anesthetized
R1713	T5764	T5758	nsubjpass	mice,anesthetized
R1714	T5765	T5758	auxpass	were,anesthetized
R1715	T5767	T5758	prep	with,anesthetized
R1716	T5768	T5769	compound	ketamine,xylazine
R1717	T5769	T5767	pobj	xylazine,with
R1718	T5770	T5769	punct	/,xylazine
R1719	T5771	T5772	punct	(,mg
R1720	T5772	T5769	parataxis	mg,xylazine
R1721	T5773	T5774	nummod	80,mg
R1722	T5774	T5772	dep	mg,mg
R1723	T5775	T5776	punct	/,kg
R1724	T5776	T5774	prep	kg,mg
R1725	T5777	T5772	punct	", ",mg
R1726	T5778	T5772	nummod	5,mg
R1727	T5779	T5780	punct	/,kg
R1728	T5780	T5772	prep	kg,mg
R1729	T5781	T5772	punct	),mg
R1730	T5782	T5766	punct	", ",prewarmed
R1731	T5783	T5784	det	the,tail
R1732	T5784	T5766	nsubj	tail,prewarmed
R1733	T5785	T5766	prep	for,prewarmed
R1734	T5786	T5787	nummod	5,min
R1735	T5787	T5785	pobj	min,for
R1736	T5788	T5766	prep	in,prewarmed
R1737	T5789	T5790	nummod	10,mL
R1738	T5790	T5788	pobj	mL,in
R1739	T5791	T5790	prep	of,mL
R1740	T5792	T5791	pobj	saline,of
R1741	T5793	T5792	prep	at,saline
R1742	T5794	T5795	nummod	37,°C
R1743	T5795	T5793	pobj	°C,at
R1744	T5796	T5766	prep	in,prewarmed
R1745	T5797	T5798	det	a,bath
R1746	T5798	T5796	pobj	bath,in
R1747	T5799	T5798	compound	water,bath
R1748	T5800	T5766	punct	.,prewarmed
R1749	T5802	T5803	det	The,tail
R1750	T5803	T5804	nsubjpass	tail,lifted
R1751	T5805	T5804	auxpass	was,lifted
R1752	T5806	T5804	prep	from,lifted
R1753	T5807	T5808	det	the,saline
R1754	T5808	T5806	pobj	saline,from
R1755	T5809	T5804	cc	and,lifted
R1756	T5810	T5811	det	a,segment
R1757	T5811	T5815	nsubj	segment,amputated
R1758	T5812	T5813	nummod	5,mm
R1759	T5813	T5811	compound	mm,segment
R1760	T5814	T5811	compound	tail,segment
R1761	T5815	T5804	conj	amputated,lifted
R1762	T5816	T5815	cc	and,amputated
R1763	T5817	T5818	advmod	immediately,returned
R1764	T5818	T5815	conj	returned,amputated
R1765	T5819	T5818	prep	to,returned
R1766	T5820	T5821	det	the,saline
R1767	T5821	T5819	pobj	saline,to
R1768	T5822	T5815	punct	.,amputated
R1769	T5824	T5825	compound	Bleeding,time
R1770	T5825	T5826	nsubjpass	time,measured
R1771	T5827	T5826	auxpass	was,measured
R1772	T5828	T5826	prep	as,measured
R1773	T5829	T5830	det	the,time
R1774	T5830	T5828	pobj	time,as
R1775	T5831	T5830	prep	between,time
R1776	T5832	T5833	det	the,start
R1777	T5833	T5831	pobj	start,between
R1778	T5834	T5833	prep	of,start
R1779	T5835	T5834	pobj	bleeding,of
R1780	T5836	T5831	prep	to,between
R1781	T5837	T5836	pobj	cessation,to
R1782	T5838	T5837	prep	of,cessation
R1783	T5839	T5838	pobj	bleeding,of
R1784	T5840	T5826	punct	.,measured
R1785	T5842	T5843	prep	With,measured
R1786	T5844	T5845	det	the,tail
R1787	T5845	T5846	nsubj	tail,remaining
R1788	T5846	T5842	pcomp	remaining,With
R1789	T5847	T5846	prep	in,remaining
R1790	T5848	T5849	det	the,solution
R1791	T5849	T5847	pobj	solution,in
R1792	T5850	T5849	amod	same,solution
R1793	T5851	T5849	compound	saline,solution
R1794	T5852	T5843	punct	", ",measured
R1795	T5853	T5854	det	the,time
R1796	T5854	T5843	nsubjpass	time,measured
R1797	T5855	T5854	compound	rebleeding,time
R1798	T5856	T5843	auxpass	was,measured
R1799	T5857	T5843	prep	from,measured
R1800	T5858	T5859	det	the,time
R1801	T5859	T5857	pobj	time,from
R1802	T5860	T5859	prep	between,time
R1803	T5861	T5862	compound	bleeding,cessation
R1804	T5862	T5860	pobj	cessation,between
R1805	T5863	T5862	cc	and,cessation
R1806	T5864	T5865	det	the,start
R1807	T5865	T5862	conj	start,cessation
R1808	T5866	T5865	prep	of,start
R1809	T5867	T5868	det	the,bleeding
R1810	T5868	T5866	pobj	bleeding,of
R1811	T5869	T5868	amod	second,bleeding
R1812	T5870	T5843	punct	.,measured
R1813	T6393	T6394	nmod	Coagulation,assays
R1814	T6395	T6393	punct	", ",Coagulation
R1815	T6396	T6393	conj	Plg,Coagulation
R1816	T6397	T6396	punct	", ",Plg
R1817	T6398	T6399	compound	α2,antiplasmin
R1818	T6399	T6396	conj	antiplasmin,Plg
R1819	T6400	T6399	punct	-,antiplasmin
R1820	T6401	T6399	punct	", ",antiplasmin
R1821	T6402	T6399	conj	fibrinogen,antiplasmin
R1822	T6403	T6402	punct	", ",fibrinogen
R1823	T6404	T6402	conj	fibrinolytic,fibrinogen
R1824	T6405	T6404	cc	and,fibrinolytic
R1825	T6406	T6404	conj	PAI,fibrinolytic
R1826	T6407	T6406	punct	-,PAI
R1827	T6408	T6406	nummod	1,PAI
R1828	T6410	T6411	nsubjpass	Mice,anesthetized
R1829	T6412	T6411	auxpass	were,anesthetized
R1830	T6413	T6411	prep	with,anesthetized
R1831	T6414	T6413	pobj	Isoflurane,with
R1832	T6415	T6416	punct	(,Abbott
R1833	T6416	T6414	parataxis	Abbott,Isoflurane
R1834	T6417	T6416	punct	),Abbott
R1835	T6418	T6411	punct	", ",anesthetized
R1836	T6419	T6411	dep	bled,anesthetized
R1837	T6420	T6419	prep	from,bled
R1838	T6421	T6422	det	the,sinus
R1839	T6422	T6420	pobj	sinus,from
R1840	T6423	T6422	amod	orbital,sinus
R1841	T6424	T6419	prep	into,bled
R1842	T6425	T6426	amod	uncoated,tubes
R1843	T6426	T6424	pobj	tubes,into
R1844	T6427	T6426	amod	capillary,tubes
R1845	T6428	T6411	punct	", ",anesthetized
R1846	T6429	T6411	cc	and,anesthetized
R1847	T6430	T6431	det	a,drop
R1848	T6431	T6432	nsubj	drop,placed
R1849	T6432	T6411	conj	placed,anesthetized
R1850	T6433	T6431	prep	of,drop
R1851	T6434	T6433	pobj	blood,of
R1852	T6435	T6432	advmod	immediately,placed
R1853	T6436	T6432	prep	on,placed
R1854	T6437	T6438	det	a,strip
R1855	T6438	T6436	pobj	strip,on
R1856	T6439	T6438	compound	reagent,strip
R1857	T6440	T6441	punct	(,Synbiotics
R1858	T6441	T6438	parataxis	Synbiotics,strip
R1859	T6442	T6441	punct	),Synbiotics
R1860	T6443	T6432	prep	for,placed
R1861	T6444	T6445	nmod	prothrombin,time
R1862	T6445	T6446	nmod	time,determinations
R1863	T6446	T6443	pobj	determinations,for
R1864	T6447	T6445	punct	(,time
R1865	T6448	T6445	appos	PT,time
R1866	T6449	T6445	punct	),time
R1867	T6450	T6445	cc	or,time
R1868	T6451	T6452	amod	activated,time
R1869	T6452	T6445	conj	time,time
R1870	T6453	T6452	amod	partial,time
R1871	T6454	T6452	compound	thromboplastin,time
R1872	T6455	T6452	punct	(,time
R1873	T6456	T6452	appos	aPTT,time
R1874	T6457	T6446	punct	),determinations
R1875	T6458	T6432	cc	and,placed
R1876	T6459	T6432	conj	inserted,placed
R1877	T6460	T6459	prep	into,inserted
R1878	T6461	T6462	det	the,Analyzer
R1879	T6462	T6460	pobj	Analyzer,into
R1880	T6463	T6462	amod	precalibrated,Analyzer
R1881	T6464	T6462	compound	Coagulation,Analyzer
R1882	T6465	T6466	punct	(,Synbiotics
R1883	T6466	T6462	parataxis	Synbiotics,Analyzer
R1884	T6467	T6466	dep	SCA2000,Synbiotics
R1885	T6468	T6466	punct	", ",Synbiotics
R1886	T6469	T6466	punct	),Synbiotics
R1887	T6470	T6432	punct	.,placed
R1888	T6472	T6473	nmod	PAI,activity
R1889	T6473	T6476	nsubjpass	activity,determined
R1890	T6474	T6472	punct	-,PAI
R1891	T6475	T6472	nummod	1,PAI
R1892	T6477	T6476	auxpass	was,determined
R1893	T6478	T6476	prep	according,determined
R1894	T6479	T6478	prep	to,according
R1895	T6480	T6481	det	the,method
R1896	T6481	T6479	pobj	method,to
R1897	T6482	T6481	prep	of,method
R1898	T6483	T6482	pobj	Chandler,of
R1899	T6484	T6485	advmod	et,al
R1900	T6485	T6483	advmod	al,Chandler
R1901	T6486	T6487	punct	[,20
R1902	T6487	T6483	parataxis	20,Chandler
R1903	T6488	T6487	punct	],20
R1904	T6489	T6476	punct	.,determined
R1905	T6491	T6492	nmod	PAI,concentration
R1906	T6492	T6496	nsubjpass	concentration,determined
R1907	T6493	T6491	punct	-,PAI
R1908	T6494	T6491	nummod	1,PAI
R1909	T6495	T6492	compound	antigen,concentration
R1910	T6497	T6496	auxpass	was,determined
R1911	T6498	T6496	prep	by,determined
R1912	T6499	T6498	pobj	ELISA,by
R1913	T6500	T6501	punct	[,21
R1914	T6501	T6499	parataxis	21,ELISA
R1915	T6502	T6501	punct	],21
R1916	T6503	T6496	advcl	using,determined
R1917	T6504	T6505	nmod	sheep,PAI
R1918	T6505	T6503	dobj	PAI,using
R1919	T6506	T6505	punct	-,PAI
R1920	T6507	T6508	nmod	anti,mouse
R1921	T6508	T6505	amod	mouse,PAI
R1922	T6509	T6505	punct	-,PAI
R1923	T6510	T6505	nummod	1,PAI
R1924	T6511	T6512	punct	(,Diagnostica
R1925	T6512	T6505	parataxis	Diagnostica,PAI
R1926	T6513	T6512	compound	American,Diagnostica
R1927	T6514	T6512	punct	),Diagnostica
R1928	T6515	T6503	prep	as,using
R1929	T6516	T6517	det	the,antibody
R1930	T6517	T6515	pobj	antibody,as
R1931	T6518	T6517	compound	capture,antibody
R1932	T6519	T6503	cc	and,using
R1933	T6520	T6521	compound	mouse,PAI
R1934	T6521	T6503	conj	PAI,using
R1935	T6522	T6521	punct	-,PAI
R1936	T6523	T6521	nummod	1,PAI
R1937	T6524	T6525	punct	(,Diagnostica
R1938	T6525	T6521	parataxis	Diagnostica,PAI
R1939	T6526	T6525	compound	American,Diagnostica
R1940	T6527	T6525	punct	),Diagnostica
R1941	T6528	T6521	prep	as,PAI
R1942	T6529	T6530	det	the,standard
R1943	T6530	T6528	pobj	standard,as
R1944	T6531	T6532	punct	(,ng
R1945	T6532	T6530	parataxis	ng,standard
R1946	T6533	T6534	quantmod	0,3.5
R1947	T6534	T6532	nummod	3.5,ng
R1948	T6535	T6534	punct	–,3.5
R1949	T6536	T6537	punct	/,mL
R1950	T6537	T6532	prep	mL,ng
R1951	T6538	T6532	punct	),ng
R1952	T6539	T6496	punct	.,determined
R1953	T6541	T6542	nsubjpass	Plg,determined
R1954	T6543	T6542	auxpass	was,determined
R1955	T6544	T6542	prep	with,determined
R1956	T6545	T6546	det	a,assay
R1957	T6546	T6544	pobj	assay,with
R1958	T6547	T6546	amod	chromogenic,assay
R1959	T6548	T6549	punct	[,22
R1960	T6549	T6542	parataxis	22,determined
R1961	T6550	T6549	punct	],22
R1962	T6551	T6542	cc	and,determined
R1963	T6552	T6553	det	the,activity
R1964	T6553	T6555	nsubj	activity,determined
R1965	T6554	T6553	amod	fibrinolytic,activity
R1966	T6555	T6542	conj	determined,determined
R1967	T6556	T6555	prep	by,determined
R1968	T6557	T6558	compound	fibrin,degradation
R1969	T6558	T6556	pobj	degradation,by
R1970	T6559	T6560	punct	[,23
R1971	T6560	T6555	parataxis	23,determined
R1972	T6561	T6560	punct	],23
R1973	T6562	T6555	punct	.,determined
R1974	T6564	T6565	prep	For,used
R1975	T6566	T6567	det	the,controls
R1976	T6567	T6564	pobj	controls,For
R1977	T6568	T6567	amod	negative,controls
R1978	T6569	T6567	prep	in,controls
R1979	T6570	T6571	det	these,assays
R1980	T6571	T6569	pobj	assays,in
R1981	T6572	T6565	punct	", ",used
R1982	T6573	T6565	nsubjpass	plasma,used
R1983	T6574	T6573	prep	from,plasma
R1984	T6575	T6576	npadvmod	PAI,deficient
R1985	T6576	T6581	amod	deficient,mice
R1986	T6577	T6575	punct	-,PAI
R1987	T6578	T6575	nummod	1,PAI
R1988	T6579	T6575	cc	or,PAI
R1989	T6580	T6575	conj	Plg,PAI
R1990	T6581	T6574	pobj	mice,from
R1991	T6582	T6565	auxpass	was,used
R1992	T6583	T6565	punct	.,used
R1993	T6585	T6586	advmod	Functionally,active
R1994	T6586	T6587	amod	active,antiplasmin
R1995	T6587	T6591	nsubjpass	antiplasmin,determined
R1996	T6588	T6587	compound	mouse,antiplasmin
R1997	T6589	T6587	compound	α2,antiplasmin
R1998	T6590	T6587	punct	-,antiplasmin
R1999	T6592	T6591	auxpass	was,determined
R2000	T6593	T6591	prep	with,determined
R2001	T6594	T6595	det	a,assay
R2002	T6595	T6593	pobj	assay,with
R2003	T6596	T6597	compound	plasmin,capture
R2004	T6597	T6595	compound	capture,assay
R2005	T6598	T6595	cc	and,assay
R2006	T6599	T6595	conj	detection,assay
R2007	T6600	T6599	prep	with,detection
R2008	T6601	T6602	det	a,antibody
R2009	T6602	T6600	pobj	antibody,with
R2010	T6603	T6602	compound	mouse,antibody
R2011	T6604	T6605	punct	(,Innovations
R2012	T6605	T6602	parataxis	Innovations,antibody
R2013	T6606	T6605	compound	Molecular,Innovations
R2014	T6607	T6605	punct	", ",Innovations
R2015	T6608	T6605	npadvmod	Southfield,Innovations
R2016	T6609	T6605	punct	", ",Innovations
R2017	T6610	T6605	npadvmod	MI,Innovations
R2018	T6611	T6605	punct	),Innovations
R2019	T6612	T6591	punct	", ",determined
R2020	T6613	T6591	cc	and,determined
R2021	T6614	T6591	conj	fibrinogen,determined
R2022	T6615	T6614	prep	with,fibrinogen
R2023	T6616	T6617	det	an,assay
R2024	T6617	T6615	pobj	assay,with
R2025	T6618	T6617	compound	ELISA,assay
R2026	T6619	T6617	prep	with,assay
R2027	T6620	T6619	pobj	antibodies,with
R2028	T6621	T6622	dep	that,recognize
R2029	T6622	T6620	relcl	recognize,antibodies
R2030	T6623	T6624	compound	mouse,fibrinogen
R2031	T6624	T6622	dobj	fibrinogen,recognize
R2032	T6625	T6626	punct	(,BioMed
R2033	T6626	T6620	parataxis	BioMed,antibodies
R2034	T6627	T6626	compound	Hyphen,BioMed
R2035	T6628	T6626	punct	", ",BioMed
R2036	T6629	T6626	npadvmod	France,BioMed
R2037	T6630	T6626	punct	),BioMed
R2038	T6631	T6614	punct	.,fibrinogen
R2039	T6809	T6810	amod	Histochemical,analysis
R2040	T6811	T6809	cc	and,Histochemical
R2041	T6812	T6809	conj	immunohistochemistry,Histochemical
R2042	T6814	T6815	det	The,tails
R2043	T6815	T6817	nsubjpass	tails,sectioned
R2044	T6816	T6815	amod	frozen,tails
R2045	T6818	T6815	cc	or,tails
R2046	T6819	T6820	amod	injured,carotids
R2047	T6820	T6815	conj	carotids,tails
R2048	T6821	T6815	prep	in,tails
R2049	T6822	T6821	pobj	OCT,in
R2050	T6823	T6817	auxpass	were,sectioned
R2051	T6824	T6817	prep	at,sectioned
R2052	T6825	T6826	nummod	5,μm
R2053	T6826	T6827	compound	μm,thickness
R2054	T6827	T6824	pobj	thickness,at
R2055	T6828	T6817	cc	and,sectioned
R2056	T6829	T6817	conj	stained,sectioned
R2057	T6830	T6829	prep	with,stained
R2058	T6831	T6832	poss	Masson,Trichrome
R2059	T6832	T6830	pobj	Trichrome,with
R2060	T6833	T6831	case	's,Masson
R2061	T6834	T6835	punct	(,Diagnostics
R2062	T6835	T6832	parataxis	Diagnostics,Trichrome
R2063	T6836	T6835	dep	HT,Diagnostics
R2064	T6837	T6836	nummod	15,HT
R2065	T6838	T6835	punct	", ",Diagnostics
R2066	T6839	T6835	compound	Sigma,Diagnostics
R2067	T6840	T6835	punct	),Diagnostics
R2068	T6841	T6817	punct	.,sectioned
R2069	T6843	T6844	prep	For,measured
R2070	T6845	T6846	amod	quantitative,analysis
R2071	T6846	T6843	pobj	analysis,For
R2072	T6847	T6846	prep	of,analysis
R2073	T6848	T6849	compound	collagen,area
R2074	T6849	T6847	pobj	area,of
R2075	T6850	T6846	prep	in,analysis
R2076	T6851	T6852	det	the,sections
R2077	T6852	T6850	pobj	sections,in
R2078	T6853	T6852	compound	tail,sections
R2079	T6854	T6844	punct	", ",measured
R2080	T6855	T6856	nummod	four,sections
R2081	T6856	T6844	nsubjpass	sections,measured
R2082	T6857	T6856	prep	from,sections
R2083	T6858	T6859	quantmod	2,3
R2084	T6859	T6861	nummod	3,sites
R2085	T6860	T6859	punct	–,3
R2086	T6861	T6857	pobj	sites,from
R2087	T6862	T6844	auxpass	were,measured
R2088	T6863	T6844	advcl	using,measured
R2089	T6864	T6865	npadvmod	computer,assisted
R2090	T6865	T6866	amod	assisted,analysis
R2091	T6866	T6863	dobj	analysis,using
R2092	T6867	T6866	compound	image,analysis
R2093	T6868	T6869	punct	(,Cybernetics
R2094	T6869	T6863	parataxis	Cybernetics,using
R2095	T6870	T6871	compound	Image,Plus
R2096	T6871	T6869	dep	Plus,Cybernetics
R2097	T6872	T6871	punct	-,Plus
R2098	T6873	T6871	compound	Pro,Plus
R2099	T6874	T6869	punct	", ",Cybernetics
R2100	T6875	T6869	punct	),Cybernetics
R2101	T6876	T6844	punct	.,measured
R2102	T6878	T6879	prep	For,analyzed
R2103	T6880	T6881	det	the,determination
R2104	T6881	T6878	pobj	determination,For
R2105	T6882	T6881	compound	area,determination
R2106	T6883	T6881	prep	of,determination
R2107	T6884	T6885	det	the,lumen
R2108	T6885	T6883	pobj	lumen,of
R2109	T6886	T6885	amod	injured,lumen
R2110	T6887	T6885	compound	carotid,lumen
R2111	T6888	T6879	punct	", ",analyzed
R2112	T6889	T6890	quantmod	3,4
R2113	T6890	T6892	nummod	4,sections
R2114	T6891	T6890	punct	–,4
R2115	T6892	T6879	nsubjpass	sections,analyzed
R2116	T6893	T6892	prep	from,sections
R2117	T6894	T6895	amod	different,sites
R2118	T6895	T6893	pobj	sites,from
R2119	T6896	T6897	advmod	approximately,100
R2120	T6897	T6898	nummod	100,μm
R2121	T6898	T6899	npadvmod	μm,apart
R2122	T6899	T6895	advmod	apart,sites
R2123	T6900	T6879	auxpass	were,analyzed
R2124	T6901	T6879	cc	and,analyzed
R2125	T6902	T6879	conj	averaged,analyzed
R2126	T6903	T6902	prep	for,averaged
R2127	T6904	T6905	det	each,mouse
R2128	T6905	T6903	pobj	mouse,for
R2129	T6906	T6879	punct	.,analyzed
R2130	T7167	T7168	nsubjpass	Data,presented
R2131	T7169	T7168	auxpass	are,presented
R2132	T7170	T7168	prep	as,presented
R2133	T7171	T7172	nmod	mean,SEM
R2134	T7172	T7170	pobj	SEM,as
R2135	T7173	T7172	punct	±,SEM
R2136	T7174	T7168	punct	.,presented
R2137	T7176	T7177	det	The,analysis
R2138	T7177	T7179	nsubjpass	analysis,compared
R2139	T7178	T7177	amod	statistical,analysis
R2140	T7180	T7177	prep	for,analysis
R2141	T7181	T7180	pobj	comparisons,for
R2142	T7182	T7181	prep	between,comparisons
R2143	T7183	T7184	nmod	A,J
R2144	T7184	T7186	nmod	J,mice
R2145	T7185	T7184	punct	/,J
R2146	T7186	T7182	pobj	mice,between
R2147	T7187	T7184	cc	and,J
R2148	T7188	T7184	conj	B6,J
R2149	T7189	T7182	cc	and,between
R2150	T7190	T7182	conj	between,between
R2151	T7191	T7192	amod	wild,type
R2152	T7192	T7194	nmod	type,littermates
R2153	T7193	T7192	punct	-,type
R2154	T7194	T7190	pobj	littermates,between
R2155	T7195	T7192	punct	(,type
R2156	T7196	T7192	appos	WT,type
R2157	T7197	T7192	punct	),type
R2158	T7198	T7192	cc	and,type
R2159	T7199	T7192	conj	Plg,type
R2160	T7200	T7199	punct	-,Plg
R2161	T7201	T7199	punct	/,Plg
R2162	T7202	T7199	punct	-,Plg
R2163	T7203	T7179	auxpass	was,compared
R2164	T7204	T7179	prep	with,compared
R2165	T7205	T7206	det	a,test
R2166	T7206	T7204	pobj	test,with
R2167	T7207	T7208	advmod	two,tailed
R2168	T7208	T7206	amod	tailed,test
R2169	T7209	T7208	punct	-,tailed
R2170	T7210	T7206	compound	t,test
R2171	T7211	T7206	punct	-,test
R2172	T7212	T7179	punct	.,compared
R2173	T7214	T7215	nsubjpass	Differences,determined
R2174	T7216	T7214	prep	among,Differences
R2175	T7217	T7218	nmod	B6,mice
R2176	T7218	T7216	pobj	mice,among
R2177	T7219	T7217	punct	", ",B6
R2178	T7220	T7217	appos	Lepob,B6
R2179	T7221	T7217	punct	", ",B6
R2180	T7222	T7217	appos	PAI,B6
R2181	T7223	T7222	punct	-,PAI
R2182	T7224	T7222	nummod	1,PAI
R2183	T7225	T7222	punct	-,PAI
R2184	T7226	T7222	punct	/,PAI
R2185	T7227	T7222	punct	-,PAI
R2186	T7228	T7215	auxpass	were,determined
R2187	T7229	T7215	agent	by,determined
R2188	T7230	T7231	det	a,ANOVA
R2189	T7231	T7229	pobj	ANOVA,by
R2190	T7232	T7233	nummod	one,way
R2191	T7233	T7231	compound	way,ANOVA
R2192	T7234	T7233	punct	-,way
R2193	T7235	T7231	cc	and,ANOVA
R2194	T7236	T7237	det	a,post-test
R2195	T7237	T7231	conj	post-test,ANOVA
R2196	T7238	T7239	compound	Newman,Keuls
R2197	T7239	T7237	compound	Keuls,post-test
R2198	T7240	T7239	punct	-,Keuls
R2199	T7241	T7215	punct	.,determined
R2200	T7243	T7244	det	A,value
R2201	T7244	T7245	nsubjpass	value,considered
R2202	T7246	T7244	prep	of,value
R2203	T7247	T7246	pobj	P,of
R2204	T7248	T7249	punct	<,0.05
R2205	T7249	T7247	amod	0.05,P
R2206	T7250	T7245	auxpass	was,considered
R2207	T7251	T7245	oprd	significant,considered
R2208	T7252	T7245	punct	.,considered
R2209	T7254	T7255	det	The,analysis
R2210	T7255	T7257	nsubjpass	analysis,determined
R2211	T7256	T7255	amod	statistical,analysis
R2212	T7258	T7255	prep	for,analysis
R2213	T7259	T7258	pobj	comparisons,for
R2214	T7260	T7259	prep	between,comparisons
R2215	T7261	T7262	compound	B6,mice
R2216	T7262	T7260	pobj	mice,between
R2217	T7263	T7262	cc	and,mice
R2218	T7264	T7262	conj	CSS,mice
R2219	T7265	T7257	auxpass	were,determined
R2220	T7266	T7257	prep	with,determined
R2221	T7267	T7268	nummod	two,tail
R2222	T7268	T7270	compound	tail,tests
R2223	T7269	T7268	punct	-,tail
R2224	T7270	T7266	pobj	tests,with
R2225	T7271	T7270	compound	t,tests
R2226	T7272	T7270	punct	-,tests
R2227	T7273	T7257	cc	and,determined
R2228	T7274	T7275	det	the,level
R2229	T7275	T7276	nsubj	level,determined
R2230	T7276	T7257	conj	determined,determined
R2231	T7277	T7275	prep	of,level
R2232	T7278	T7279	det	the,values
R2233	T7279	T7277	pobj	values,of
R2234	T7280	T7279	amod	significant,values
R2235	T7281	T7279	compound	P,values
R2236	T7282	T7279	punct	-,values
R2237	T7283	T7284	punct	(,see
R2238	T7284	T7275	parataxis	see,level
R2239	T7285	T7286	compound	figure,legends
R2240	T7286	T7284	dobj	legends,see
R2241	T7287	T7284	punct	),see
R2242	T7288	T7276	prep	with,determined
R2243	T7289	T7290	det	a,correction
R2244	T7290	T7288	pobj	correction,with
R2245	T7291	T7290	compound	Bonferroni,correction
R2246	T7292	T7293	aux	to,account
R2247	T7293	T7290	advcl	account,correction
R2248	T7294	T7293	prep	for,account
R2249	T7295	T7296	compound	multihypothesis,testing
R2250	T7296	T7294	pobj	testing,for
R2251	T7297	T7298	punct	[,13
R2252	T7298	T7276	parataxis	13,determined
R2253	T7299	T7298	punct	],13
R2254	T7300	T7276	punct	.,determined
R2255	T8036	T8037	amod	Marked,differences
R2256	T8038	T8037	prep	in,differences
R2257	T8039	T8040	amod	arterial,thrombus
R2258	T8040	T8041	compound	thrombus,formation
R2259	T8041	T8038	pobj	formation,in
R2260	T8042	T8037	prep	in,differences
R2261	T8043	T8044	nmod	B6,mice
R2262	T8044	T8042	pobj	mice,in
R2263	T8045	T8043	cc	and,B6
R2264	T8046	T8047	compound	A,J
R2265	T8047	T8043	conj	J,B6
R2266	T8048	T8047	punct	/,J
R2267	T8050	T8051	det	The,model
R2268	T8051	T8056	nsubjpass	model,used
R2269	T8052	T8051	nmod	FeCl3,model
R2270	T8053	T8054	amod	cartoid,artery
R2271	T8054	T8051	compound	artery,model
R2272	T8055	T8051	compound	injury,model
R2273	T8057	T8058	punct	[,24
R2274	T8058	T8051	parataxis	24,model
R2275	T8059	T8058	punct	],24
R2276	T8060	T8051	punct	", ",model
R2277	T8061	T8062	det	a,model
R2278	T8062	T8051	appos	model,model
R2279	T8063	T8064	amod	well,characterized
R2280	T8064	T8062	amod	characterized,model
R2281	T8065	T8064	punct	-,characterized
R2282	T8066	T8067	amod	arterial,thrombosis
R2283	T8067	T8062	compound	thrombosis,model
R2284	T8068	T8056	punct	", ",used
R2285	T8069	T8056	auxpass	was,used
R2286	T8070	T8071	aux	to,induce
R2287	T8071	T8056	advcl	induce,used
R2288	T8072	T8073	det	an,thrombus
R2289	T8073	T8071	dobj	thrombus,induce
R2290	T8074	T8073	amod	occlusive,thrombus
R2291	T8075	T8071	prep	in,induce
R2292	T8076	T8077	det	the,strains
R2293	T8077	T8075	pobj	strains,in
R2294	T8078	T8077	nmod	B6,strains
R2295	T8079	T8078	cc	and,B6
R2296	T8080	T8081	compound	A,J
R2297	T8081	T8078	conj	J,B6
R2298	T8082	T8081	punct	/,J
R2299	T8083	T8077	compound	mouse,strains
R2300	T8084	T8077	prep	under,strains
R2301	T8085	T8084	pobj	investigation,under
R2302	T8086	T8056	punct	.,used
R2303	T8088	T8089	det	A,difference
R2304	T8089	T8091	nsubjpass	difference,found
R2305	T8090	T8089	amod	marked,difference
R2306	T8092	T8089	prep	in,difference
R2307	T8093	T8094	amod	arterial,thrombus
R2308	T8094	T8095	compound	thrombus,occlusion
R2309	T8095	T8096	compound	occlusion,time
R2310	T8096	T8092	pobj	time,in
R2311	T8097	T8091	auxpass	was,found
R2312	T8098	T8091	prep	between,found
R2313	T8099	T8100	det	the,B6
R2314	T8100	T8098	pobj	B6,between
R2315	T8101	T8100	cc	and,B6
R2316	T8102	T8103	det	the,J
R2317	T8103	T8106	compound	J,mice
R2318	T8104	T8103	compound	A,J
R2319	T8105	T8103	punct	/,J
R2320	T8106	T8100	conj	mice,B6
R2321	T8107	T8108	punct	(,1A
R2322	T8108	T8091	parataxis	1A,found
R2323	T8109	T8108	compound	Figure,1A
R2324	T8110	T8108	punct	),1A
R2325	T8111	T8091	punct	.,found
R2326	T8113	T8114	det	The,time
R2327	T8114	T8116	nsubj	time,was
R2328	T8115	T8114	compound	occlusion,time
R2329	T8117	T8114	prep	in,time
R2330	T8118	T8119	det	the,mice
R2331	T8119	T8117	pobj	mice,in
R2332	T8120	T8121	compound	A,J
R2333	T8121	T8119	compound	J,mice
R2334	T8122	T8121	punct	/,J
R2335	T8123	T8124	advmod	2-fold,less
R2336	T8124	T8116	acomp	less,was
R2337	T8125	T8124	prep	than,less
R2338	T8126	T8125	prep	for,than
R2339	T8127	T8128	det	the,mice
R2340	T8128	T8126	pobj	mice,for
R2341	T8129	T8128	compound	B6,mice
R2342	T8130	T8116	punct	.,was
R2343	T8132	T8133	det	A,dose
R2344	T8133	T8136	nsubjpass	dose,tested
R2345	T8134	T8135	nummod	5,%
R2346	T8135	T8133	compound	%,dose
R2347	T8137	T8133	prep	of,dose
R2348	T8138	T8137	pobj	FeCl3,of
R2349	T8139	T8136	auxpass	was,tested
R2350	T8140	T8136	prep	in,tested
R2351	T8141	T8142	det	the,mice
R2352	T8142	T8140	pobj	mice,in
R2353	T8143	T8144	nmod	A,J
R2354	T8144	T8142	nmod	J,mice
R2355	T8145	T8144	punct	/,J
R2356	T8146	T8144	cc	and,J
R2357	T8147	T8144	conj	B6,J
R2358	T8148	T8136	cc	and,tested
R2359	T8149	T8150	det	the,time
R2360	T8150	T8152	nsubj	time,was
R2361	T8151	T8150	compound	occlusion,time
R2362	T8152	T8136	conj	was,tested
R2363	T8153	T8152	acomp	lower,was
R2364	T8154	T8153	prep	in,lower
R2365	T8155	T8156	det	the,J
R2366	T8156	T8154	pobj	J,in
R2367	T8157	T8156	compound	A,J
R2368	T8158	T8156	punct	/,J
R2369	T8159	T8153	prep	than,lower
R2370	T8160	T8161	det	the,B6
R2371	T8161	T8159	pobj	B6,than
R2372	T8162	T8159	pobj	mice,than
R2373	T8163	T8152	punct	", ",was
R2374	T8164	T8165	det	the,results
R2375	T8165	T8152	npadvmod	results,was
R2376	T8166	T8165	amod	same,results
R2377	T8167	T8165	prep	as,results
R2378	T8168	T8167	prep	with,as
R2379	T8169	T8170	det	the,dose
R2380	T8170	T8168	pobj	dose,with
R2381	T8171	T8172	nummod	10,%
R2382	T8172	T8170	compound	%,dose
R2383	T8173	T8152	punct	.,was
R2384	T8175	T8176	det	The,time
R2385	T8176	T8178	nsubj	time,were
R2386	T8177	T8176	compound	occlusion,time
R2387	T8179	T8180	punct	(,min
R2388	T8180	T8176	parataxis	min,time
R2389	T8181	T8180	prep	for,min
R2390	T8182	T8183	preconj	both,B6
R2391	T8183	T8181	pobj	B6,for
R2392	T8184	T8185	punct	(,3
R2393	T8185	T8183	parataxis	3,B6
R2394	T8186	T8185	quantmod	15,3
R2395	T8187	T8185	punct	±,3
R2396	T8188	T8185	punct	", ",3
R2397	T8189	T8190	nsubj	n,3
R2398	T8190	T8185	ccomp	3,3
R2399	T8191	T8190	punct	=,3
R2400	T8192	T8185	punct	),3
R2401	T8193	T8183	cc	and,B6
R2402	T8194	T8195	compound	A,J
R2403	T8195	T8183	conj	J,B6
R2404	T8196	T8195	punct	/,J
R2405	T8197	T8198	punct	(,1
R2406	T8198	T8195	parataxis	1,J
R2407	T8199	T8198	quantmod	8,1
R2408	T8200	T8198	punct	±,1
R2409	T8201	T8198	punct	", ",1
R2410	T8202	T8203	nsubj	n,3
R2411	T8203	T8198	ccomp	3,1
R2412	T8204	T8203	punct	=,3
R2413	T8205	T8198	punct	),1
R2414	T8206	T8176	prep	at,time
R2415	T8207	T8208	nummod	5,%
R2416	T8208	T8206	pobj	%,at
R2417	T8209	T8178	acomp	longer,were
R2418	T8210	T8209	prep	than,longer
R2419	T8211	T8210	prep	at,than
R2420	T8212	T8213	nummod	10,%
R2421	T8213	T8211	pobj	%,at
R2422	T8214	T8178	prep	for,were
R2423	T8215	T8214	pobj	B6,for
R2424	T8216	T8217	punct	(,1
R2425	T8217	T8215	parataxis	1,B6
R2426	T8218	T8217	quantmod	10,1
R2427	T8219	T8217	punct	±,1
R2428	T8220	T8217	punct	", ",1
R2429	T8221	T8222	nsubj	n,17
R2430	T8222	T8217	ccomp	17,1
R2431	T8223	T8222	punct	=,17
R2432	T8224	T8215	cc	and,B6
R2433	T8225	T8226	compound	A,J
R2434	T8226	T8215	conj	J,B6
R2435	T8227	T8226	punct	/,J
R2436	T8228	T8229	punct	(,2
R2437	T8229	T8226	parataxis	2,J
R2438	T8230	T8229	quantmod	5,2
R2439	T8231	T8229	punct	±,2
R2440	T8232	T8229	punct	", ",2
R2441	T8233	T8234	nsubj	n,14
R2442	T8234	T8229	ccomp	14,2
R2443	T8235	T8234	punct	=,14
R2444	T8236	T8229	punct	),2
R2445	T8237	T8178	punct	.,were
R2446	T8239	T8240	det	The,curves
R2447	T8240	T8241	nsubj	curves,indicated
R2448	T8242	T8240	prep	of,curves
R2449	T8243	T8244	compound	blood,flow
R2450	T8244	T8242	pobj	flow,of
R2451	T8245	T8240	prep	after,curves
R2452	T8246	T8247	compound	FeCl3,application
R2453	T8247	T8245	pobj	application,after
R2454	T8248	T8249	det	a,pattern
R2455	T8249	T8241	dobj	pattern,indicated
R2456	T8250	T8241	prep	with,indicated
R2457	T8251	T8252	det	a,decrease
R2458	T8252	T8250	pobj	decrease,with
R2459	T8253	T8252	amod	gradual,decrease
R2460	T8254	T8252	prep	before,decrease
R2461	T8255	T8254	pobj	occlusion,before
R2462	T8256	T8252	prep	for,decrease
R2463	T8257	T8258	det	the,mice
R2464	T8258	T8256	pobj	mice,for
R2465	T8259	T8258	compound	B6,mice
R2466	T8260	T8261	punct	(,1B
R2467	T8261	T8241	parataxis	1B,indicated
R2468	T8262	T8261	compound	Figure,1B
R2469	T8263	T8261	punct	),1B
R2470	T8264	T8241	punct	", ",indicated
R2471	T8265	T8241	cc	but,indicated
R2472	T8266	T8267	prep	for,decreased
R2473	T8267	T8241	conj	decreased,indicated
R2474	T8268	T8269	det	the,mice
R2475	T8269	T8266	pobj	mice,for
R2476	T8270	T8271	compound	A,J
R2477	T8271	T8269	compound	J,mice
R2478	T8272	T8271	punct	/,J
R2479	T8273	T8274	det	the,flow
R2480	T8274	T8267	nsubj	flow,decreased
R2481	T8275	T8274	compound	blood,flow
R2482	T8276	T8267	advmod	abruptly,decreased
R2483	T8277	T8267	prep	to,decreased
R2484	T8278	T8277	pobj	zero,to
R2485	T8279	T8280	punct	(,1C
R2486	T8280	T8267	parataxis	1C,decreased
R2487	T8281	T8280	compound	Figure,1C
R2488	T8282	T8280	punct	),1C
R2489	T8283	T8267	punct	", ",decreased
R2490	T8284	T8267	advcl	demonstrating,decreased
R2491	T8285	T8286	det	a,difference
R2492	T8286	T8284	dobj	difference,demonstrating
R2493	T8287	T8286	amod	marked,difference
R2494	T8288	T8286	prep	from,difference
R2495	T8289	T8290	det	the,strain
R2496	T8290	T8288	pobj	strain,from
R2497	T8291	T8290	compound	B6,strain
R2498	T8292	T8267	punct	.,decreased
R2499	T8294	T8295	det	The,times
R2500	T8295	T8298	nsubj	times,were
R2501	T8296	T8295	amod	mean,times
R2502	T8297	T8295	compound	occlusion,times
R2503	T8299	T8300	advmod	significantly,different
R2504	T8300	T8298	acomp	different,were
R2505	T8301	T8298	prep	between,were
R2506	T8302	T8303	det	the,strains
R2507	T8303	T8301	pobj	strains,between
R2508	T8304	T8303	nummod	two,strains
R2509	T8305	T8306	punct	(,1A
R2510	T8306	T8298	parataxis	1A,were
R2511	T8307	T8306	compound	Figure,1A
R2512	T8308	T8306	punct	),1A
R2513	T8309	T8298	punct	.,were
R2514	T8311	T8312	det	The,size
R2515	T8312	T8313	nsubj	size,was
R2516	T8314	T8312	prep	of,size
R2517	T8315	T8316	det	the,carotids
R2518	T8316	T8314	pobj	carotids,of
R2519	T8317	T8312	prep	in,size
R2520	T8318	T8319	det	the,strains
R2521	T8319	T8317	pobj	strains,in
R2522	T8320	T8319	nummod	two,strains
R2523	T8321	T8322	advmod	noticeably,different
R2524	T8322	T8313	acomp	different,was
R2525	T8323	T8313	punct	.,was
R2526	T8325	T8326	det	The,area
R2527	T8326	T8327	nsubj	area,was
R2528	T8328	T8329	punct	(,mm2
R2529	T8329	T8326	parataxis	mm2,area
R2530	T8330	T8329	punct	),mm2
R2531	T8331	T8326	prep	of,area
R2532	T8332	T8333	det	the,lumen
R2533	T8333	T8331	pobj	lumen,of
R2534	T8334	T8335	punct	(,0.007
R2535	T8335	T8333	parataxis	0.007,lumen
R2536	T8336	T8335	quantmod	0.066,0.007
R2537	T8337	T8335	punct	±,0.007
R2538	T8338	T8335	punct	", ",0.007
R2539	T8339	T8340	nsubj	n,6
R2540	T8340	T8335	ccomp	6,0.007
R2541	T8341	T8340	punct	=,6
R2542	T8342	T8335	punct	),0.007
R2543	T8343	T8344	advmod	significantly,less
R2544	T8344	T8327	acomp	less,was
R2545	T8345	T8327	prep	in,was
R2546	T8346	T8347	det	the,mice
R2547	T8347	T8345	pobj	mice,in
R2548	T8348	T8349	nmod	A,J
R2549	T8349	T8347	compound	J,mice
R2550	T8350	T8349	punct	/,J
R2551	T8351	T8327	prep	than,was
R2552	T8352	T8351	prep	for,than
R2553	T8353	T8354	compound	B6,mice
R2554	T8354	T8352	pobj	mice,for
R2555	T8355	T8356	punct	(,0.007
R2556	T8356	T8327	parataxis	0.007,was
R2557	T8357	T8356	quantmod	0.128,0.007
R2558	T8358	T8356	punct	±,0.007
R2559	T8359	T8356	punct	", ",0.007
R2560	T8360	T8361	nsubj	n,6
R2561	T8361	T8356	ccomp	6,0.007
R2562	T8362	T8361	punct	=,6
R2563	T8363	T8356	punct	),0.007
R2564	T8364	T8327	punct	.,was
R2565	T8366	T8367	advmod	However,was
R2566	T8368	T8367	punct	", ",was
R2567	T8369	T8370	det	the,ratio
R2568	T8370	T8367	nsubj	ratio,was
R2569	T8371	T8370	prep	of,ratio
R2570	T8372	T8373	det	the,thrombus
R2571	T8373	T8371	pobj	thrombus,of
R2572	T8374	T8370	prep	to,ratio
R2573	T8375	T8374	pobj	lumen,to
R2574	T8376	T8367	acomp	similar,was
R2575	T8377	T8367	prep	for,was
R2576	T8378	T8379	compound	A,J
R2577	T8379	T8377	pobj	J,for
R2578	T8380	T8379	punct	/,J
R2579	T8381	T8382	punct	(,0.03
R2580	T8382	T8379	parataxis	0.03,J
R2581	T8383	T8382	quantmod	0.63,0.03
R2582	T8384	T8382	punct	±,0.03
R2583	T8385	T8382	punct	),0.03
R2584	T8386	T8379	prep	compared,J
R2585	T8387	T8386	prep	to,compared
R2586	T8388	T8389	compound	B6,mice
R2587	T8389	T8387	pobj	mice,to
R2588	T8390	T8391	punct	(,0.09
R2589	T8391	T8389	parataxis	0.09,mice
R2590	T8392	T8391	quantmod	0.67,0.09
R2591	T8393	T8391	punct	±,0.09
R2592	T8394	T8391	punct	),0.09
R2593	T8395	T8367	punct	.,was
R2594	T8397	T8398	amod	Calculated,rates
R2595	T8398	T8401	nsubj	rates,were
R2596	T8399	T8398	compound	sheer,rates
R2597	T8400	T8398	compound	stress,rates
R2598	T8402	T8403	punct	[,25
R2599	T8403	T8398	parataxis	25,rates
R2600	T8404	T8403	punct	],25
R2601	T8405	T8406	nummod	14,%
R2602	T8406	T8407	npadvmod	%,less
R2603	T8407	T8401	acomp	less,were
R2604	T8408	T8401	prep	in,were
R2605	T8409	T8410	det	the,mice
R2606	T8410	T8408	pobj	mice,in
R2607	T8411	T8412	compound	A,J
R2608	T8412	T8410	compound	J,mice
R2609	T8413	T8412	punct	/,J
R2610	T8414	T8415	advmod	when,compared
R2611	T8415	T8401	advcl	compared,were
R2612	T8416	T8415	prep	to,compared
R2613	T8417	T8418	compound	B6,mice
R2614	T8418	T8416	pobj	mice,to
R2615	T8419	T8401	punct	.,were
R2616	T9400	T9401	amod	Marked,differences
R2617	T9402	T9401	prep	in,differences
R2618	T9403	T9404	compound	rebleeding,time
R2619	T9404	T9402	pobj	time,in
R2620	T9405	T9401	prep	in,differences
R2621	T9406	T9407	nmod	B6,mice
R2622	T9407	T9405	pobj	mice,in
R2623	T9408	T9406	cc	and,B6
R2624	T9409	T9410	compound	A,J
R2625	T9410	T9406	conj	J,B6
R2626	T9411	T9410	punct	/,J
R2627	T9413	T9414	det	The,time
R2628	T9414	T9416	nsubjpass	time,determined
R2629	T9415	T9414	compound	bleeding,time
R2630	T9417	T9414	punct	", ",time
R2631	T9418	T9419	det	an,indicator
R2632	T9419	T9414	appos	indicator,time
R2633	T9420	T9419	prep	of,indicator
R2634	T9421	T9422	amod	hemostatic,activity
R2635	T9422	T9420	pobj	activity,of
R2636	T9423	T9416	punct	", ",determined
R2637	T9424	T9416	auxpass	was,determined
R2638	T9425	T9416	prep	after,determined
R2639	T9426	T9425	pcomp	prewarming,after
R2640	T9427	T9428	det	the,tail
R2641	T9428	T9426	dobj	tail,prewarming
R2642	T9429	T9426	punct	", ",prewarming
R2643	T9430	T9426	conj	clipping,prewarming
R2644	T9431	T9432	det	a,segment
R2645	T9432	T9430	dobj	segment,clipping
R2646	T9433	T9434	nummod	5,mm
R2647	T9434	T9432	compound	mm,segment
R2648	T9435	T9430	punct	", ",clipping
R2649	T9436	T9430	conj	placing,clipping
R2650	T9437	T9438	det	the,tail
R2651	T9438	T9436	dobj	tail,placing
R2652	T9439	T9436	prep	in,placing
R2653	T9440	T9441	amod	warm,saline
R2654	T9441	T9439	pobj	saline,in
R2655	T9442	T9436	cc	and,placing
R2656	T9443	T9436	conj	measuring,placing
R2657	T9444	T9445	det	the,time
R2658	T9445	T9443	dobj	time,measuring
R2659	T9446	T9447	mark	for,stop
R2660	T9447	T9445	advcl	stop,time
R2661	T9448	T9449	det	the,bleeding
R2662	T9449	T9447	nsubj	bleeding,stop
R2663	T9450	T9447	aux	to,stop
R2664	T9451	T9416	punct	.,determined
R2665	T9453	T9454	nsubj	We,found
R2666	T9455	T9456	det	this,procedure
R2667	T9456	T9457	nsubj	procedure,was
R2668	T9457	T9454	advcl	was,found
R2669	T9458	T9457	acomp	consistent,was
R2670	T9459	T9458	cc	and,consistent
R2671	T9460	T9458	conj	reproducible,consistent
R2672	T9461	T9457	prep	in,was
R2673	T9462	T9463	amod	different,strains
R2674	T9463	T9461	pobj	strains,in
R2675	T9464	T9463	compound	mouse,strains
R2676	T9465	T9457	cc	and,was
R2677	T9466	T9457	conj	was,was
R2678	T9467	T9466	neg	not,was
R2679	T9468	T9469	npadvmod	gender,dependent
R2680	T9469	T9466	acomp	dependent,was
R2681	T9470	T9454	punct	.,found
R2682	T9472	T9473	compound	Bleeding,time
R2683	T9473	T9474	nsubj	time,was
R2684	T9475	T9474	neg	not,was
R2685	T9476	T9474	acomp	different,was
R2686	T9477	T9474	prep	in,was
R2687	T9478	T9479	compound	A,J
R2688	T9479	T9481	compound	J,mice
R2689	T9480	T9479	punct	/,J
R2690	T9481	T9477	pobj	mice,in
R2691	T9482	T9474	prep	compared,was
R2692	T9483	T9482	prep	to,compared
R2693	T9484	T9485	compound	B6,mice
R2694	T9485	T9483	pobj	mice,to
R2695	T9486	T9487	punct	(,2A
R2696	T9487	T9474	parataxis	2A,was
R2697	T9488	T9487	compound	Figure,2A
R2698	T9489	T9487	punct	),2A
R2699	T9490	T9474	punct	.,was
R2700	T9492	T9493	prep	In,tested
R2701	T9494	T9492	pobj	order,In
R2702	T9495	T9496	aux	to,determine
R2703	T9496	T9494	acl	determine,order
R2704	T9497	T9498	mark	if,altered
R2705	T9498	T9496	ccomp	altered,determine
R2706	T9499	T9500	amod	specific,pathways
R2707	T9500	T9498	nsubjpass	pathways,altered
R2708	T9501	T9498	auxpass	were,altered
R2709	T9502	T9498	prep	in,altered
R2710	T9503	T9504	det	the,strains
R2711	T9504	T9502	pobj	strains,in
R2712	T9505	T9504	nmod	B6,strains
R2713	T9506	T9505	cc	and,B6
R2714	T9507	T9508	compound	A,J
R2715	T9508	T9505	conj	J,B6
R2716	T9509	T9508	punct	/,J
R2717	T9510	T9493	punct	", ",tested
R2718	T9511	T9493	nsubjpass	mice,tested
R2719	T9512	T9511	prep	with,mice
R2720	T9513	T9514	amod	known,alterations
R2721	T9514	T9512	pobj	alterations,with
R2722	T9515	T9514	prep	in,alterations
R2723	T9516	T9515	pobj	hemostasis,in
R2724	T9517	T9511	punct	", ",mice
R2725	T9518	T9519	compound	Lepob,mice
R2726	T9519	T9511	appos	mice,mice
R2727	T9520	T9511	punct	", ",mice
R2728	T9521	T9511	cc	or,mice
R2729	T9522	T9511	conj	thrombosis,mice
R2730	T9523	T9522	punct	", ",thrombosis
R2731	T9524	T9525	nmod	Plg,mice
R2732	T9525	T9522	appos	mice,thrombosis
R2733	T9526	T9524	punct	-,Plg
R2734	T9527	T9524	punct	/,Plg
R2735	T9528	T9524	punct	-,Plg
R2736	T9529	T9524	cc	and,Plg
R2737	T9530	T9524	conj	PAI,Plg
R2738	T9531	T9530	punct	-,PAI
R2739	T9532	T9530	punct	/,PAI
R2740	T9533	T9530	punct	-,PAI
R2741	T9534	T9493	punct	", ",tested
R2742	T9535	T9493	auxpass	were,tested
R2743	T9536	T9493	advmod	also,tested
R2744	T9537	T9493	punct	.,tested
R2745	T9539	T9540	det	The,mice
R2746	T9540	T9542	nsubj	mice,have
R2747	T9541	T9540	compound	Lepob,mice
R2748	T9543	T9544	amod	impaired,aggregation
R2749	T9544	T9542	dobj	aggregation,have
R2750	T9545	T9544	compound	platelet,aggregation
R2751	T9546	T9547	punct	[,26
R2752	T9547	T9542	parataxis	26,have
R2753	T9548	T9547	punct	],26
R2754	T9549	T9542	cc	and,have
R2755	T9550	T9551	auxpass	were,evaluated
R2756	T9551	T9542	conj	evaluated,have
R2757	T9552	T9551	prep	as,evaluated
R2758	T9553	T9554	det	a,reference
R2759	T9554	T9552	pobj	reference,as
R2760	T9555	T9554	prep	for,reference
R2761	T9556	T9557	compound	platelet,function
R2762	T9557	T9555	pobj	function,for
R2763	T9558	T9542	punct	.,have
R2764	T9560	T9561	prep	In,was
R2765	T9562	T9563	det	the,mice
R2766	T9563	T9560	pobj	mice,In
R2767	T9564	T9563	compound	Lepob,mice
R2768	T9565	T9566	punct	(,2A
R2769	T9566	T9563	parataxis	2A,mice
R2770	T9567	T9566	compound	Figure,2A
R2771	T9568	T9566	punct	),2A
R2772	T9569	T9561	expl	there,was
R2773	T9570	T9571	advmod	nearly,increase
R2774	T9571	T9561	attr	increase,was
R2775	T9572	T9571	det	a,increase
R2776	T9573	T9571	advmod	10-fold,increase
R2777	T9574	T9571	prep	in,increase
R2778	T9575	T9576	compound	bleeding,time
R2779	T9576	T9574	pobj	time,in
R2780	T9577	T9571	prep	compared,increase
R2781	T9578	T9577	prep	to,compared
R2782	T9579	T9580	compound	B6,mice
R2783	T9580	T9578	pobj	mice,to
R2784	T9581	T9561	punct	.,was
R2785	T9583	T9584	compound	Bleeding,time
R2786	T9584	T9585	nsubjpass	time,increased
R2787	T9586	T9585	auxpass	was,increased
R2788	T9587	T9585	advmod	also,increased
R2789	T9588	T9585	advmod	significantly,increased
R2790	T9589	T9590	punct	(,0.0001
R2791	T9590	T9588	parataxis	0.0001,significantly
R2792	T9591	T9590	nsubj	P,0.0001
R2793	T9592	T9590	punct	=,0.0001
R2794	T9593	T9590	punct	),0.0001
R2795	T9594	T9585	prep	by,increased
R2796	T9595	T9596	nummod	66,%
R2797	T9596	T9594	pobj	%,by
R2798	T9597	T9585	prep	in,increased
R2799	T9598	T9599	det	the,mice
R2800	T9599	T9597	pobj	mice,in
R2801	T9600	T9599	nmod	Plg,mice
R2802	T9601	T9600	punct	-,Plg
R2803	T9602	T9600	punct	/,Plg
R2804	T9603	T9600	punct	-,Plg
R2805	T9604	T9585	prep	compared,increased
R2821	T9622	T9617	punct	/,PAI
R2822	T9623	T9617	punct	-,PAI
R2823	T9624	T9613	prep	compared,was
R2824	T9625	T9624	prep	to,compared
R2825	T9626	T9627	compound	B6,mice
R2826	T9627	T9625	pobj	mice,to
R2827	T9628	T9613	punct	.,was
R2828	T9630	T9631	prep	In,was
R2829	T9632	T9630	pobj	contrast,In
R2830	T9633	T9632	prep	to,contrast
R2831	T9634	T9635	det	the,mice
R2832	T9635	T9633	pobj	mice,to
R2833	T9636	T9635	compound	Lepob,mice
R2834	T9637	T9635	prep	with,mice
R2835	T9638	T9639	det	a,defect
R2836	T9639	T9637	pobj	defect,with
R2837	T9640	T9639	compound	platelet,defect
R2838	T9641	T9639	cc	and,defect
R2839	T9642	T9643	advmod	10-fold,increase
R2840	T9643	T9639	conj	increase,defect
R2841	T9644	T9643	prep	in,increase
R2842	T9645	T9646	compound	bleeding,time
R2843	T9646	T9644	pobj	time,in
R2844	T9647	T9631	punct	", ",was
R2845	T9648	T9631	expl	there,was
R2846	T9649	T9650	det	no,difference
R2847	T9650	T9631	attr	difference,was
R2848	T9651	T9650	prep	in,difference
R2849	T9652	T9653	det	the,time
R2850	T9653	T9651	pobj	time,in
R2851	T9654	T9653	compound	bleeding,time
R2852	T9655	T9653	prep	between,time
R2853	T9656	T9657	nmod	B6,mice
R2854	T9657	T9655	pobj	mice,between
R2855	T9658	T9656	cc	and,B6
R2856	T9659	T9660	compound	A,J
R2857	T9660	T9656	conj	J,B6
R2858	T9661	T9660	punct	/,J
R2859	T9662	T9631	cc	and,was
R2860	T9663	T9631	conj	suggested,was
R2861	T9664	T9665	compound	platelet,aggregation
R2862	T9665	T9666	nsubjpass	aggregation,altered
R2863	T9666	T9663	advcl	altered,suggested
R2864	T9667	T9666	auxpass	is,altered
R2865	T9668	T9666	neg	not,altered
R2866	T9669	T9666	prep	in,altered
R2867	T9670	T9671	det	these,strains
R2868	T9671	T9669	pobj	strains,in
R2869	T9672	T9671	nummod	two,strains
R2870	T9673	T9631	punct	.,was
R2905	T9712	T9709	prep	in,were
R2906	T9713	T9714	nmod	A,J
R2907	T9714	T9716	nmod	J,mice
R2908	T9715	T9714	punct	/,J
R2909	T9716	T9712	pobj	mice,in
R2910	T9717	T9718	punct	(,2.6-fold
R2911	T9718	T9714	parataxis	2.6-fold,J
R2912	T9719	T9718	punct	", ",2.6-fold
R2913	T9720	T9721	nsubj	P,0.001
R2914	T9721	T9718	ccomp	0.001,2.6-fold
R2915	T9722	T9721	punct	<,0.001
R2916	T9723	T9718	punct	),2.6-fold
R2917	T9724	T9709	prep	than,were
R2918	T9725	T9726	det	the,mice
R2919	T9726	T9724	pobj	mice,than
R2920	T9727	T9726	compound	B6,mice
R2921	T9728	T9709	punct	.,were
R2922	T9730	T9731	prep	In,was
R2923	T9732	T9730	pobj	contrast,In
R2924	T9733	T9731	punct	", ",was
R2925	T9734	T9735	det	the,time
R2926	T9735	T9731	nsubj	time,was
R2927	T9736	T9735	compound	rebleeding,time
R2928	T9737	T9738	advmod	nearly,8.5-fold
R2929	T9738	T9739	advmod	8.5-fold,less
R2930	T9739	T9731	acomp	less,was
R2931	T9740	T9731	prep	in,was
R2932	T9741	T9742	det	the,mice
R2933	T9742	T9740	pobj	mice,in
R2934	T9743	T9742	compound	Lepob,mice
R2935	T9744	T9731	prep	than,was
R2936	T9745	T9746	det	the,mice
R2937	T9746	T9744	pobj	mice,than
R2938	T9747	T9746	compound	B6,mice
R2939	T9748	T9731	punct	.,was
R2940	T9750	T9751	aux	To,determine
R2941	T9751	T9752	advcl	determine,tested
R2942	T9753	T9754	advmod	how,affect
R2943	T9754	T9751	ccomp	affect,determine
R2944	T9755	T9754	nsubj	alterations,affect
R2945	T9756	T9755	prep	in,alterations
R2946	T9757	T9758	det	the,system
R2947	T9758	T9756	pobj	system,in
R2948	T9759	T9758	amod	fibrinolytic,system
R2949	T9760	T9754	aux	may,affect
R2950	T9761	T9762	compound	rebleeding,time
R2951	T9762	T9754	dobj	time,affect
R2952	T9763	T9752	punct	", ",tested
R2953	T9764	T9765	nmod	Plg,mice
R2954	T9765	T9752	nsubjpass	mice,tested
R2955	T9766	T9764	punct	-,Plg
R2956	T9767	T9764	punct	/,Plg
R2957	T9768	T9764	punct	-,Plg
R2958	T9769	T9764	cc	and,Plg
R2959	T9770	T9764	conj	PAI,Plg
R2960	T9771	T9770	punct	-,PAI
R2961	T9772	T9770	nummod	1,PAI
R2962	T9773	T9770	punct	-,PAI
R2963	T9774	T9770	punct	/,PAI
R2964	T9775	T9770	punct	-,PAI
R2965	T9776	T9752	auxpass	were,tested
R2966	T9777	T9752	advmod	also,tested
R2967	T9778	T9779	punct	(,2B
R2968	T9779	T9752	parataxis	2B,tested
R2969	T9780	T9779	compound	Figure,2B
R2970	T9781	T9779	punct	),2B
R2971	T9782	T9752	punct	.,tested
R2972	T9784	T9785	amod	Rebleeding,time
R2973	T9785	T9786	nsubj	time,was
R2974	T9787	T9786	neg	not,was
R2975	T9788	T9786	acomp	different,was
R2976	T9789	T9786	prep	in,was
R2977	T9790	T9791	nmod	Plg,mice
R2978	T9791	T9789	pobj	mice,in
R2979	T9792	T9790	punct	-,Plg
R2980	T9793	T9790	punct	/,Plg
R2981	T9794	T9790	punct	-,Plg
R2982	T9795	T9786	prep	compared,was
R2983	T9796	T9795	prep	to,compared
R2984	T9797	T9798	compound	WT,littermates
R2985	T9798	T9796	pobj	littermates,to
R2986	T9799	T9786	punct	", ",was
R2987	T9800	T9786	cc	but,was
R2988	T9801	T9802	nmod	PAI,mice
R2989	T9802	T9808	nsubj	mice,had
R2990	T9803	T9801	punct	-,PAI
R2991	T9804	T9801	nummod	1,PAI
R2992	T9805	T9801	punct	-,PAI
R2993	T9806	T9801	punct	/,PAI
R2994	T9807	T9801	punct	-,PAI
R2995	T9808	T9786	conj	had,was
R2996	T9809	T9810	det	a,time
R2997	T9810	T9808	dobj	time,had
R2998	T9811	T9812	advmod	significantly,reduced
R2999	T9812	T9810	amod	reduced,time
R3000	T9813	T9814	punct	(,0.05
R3001	T9814	T9811	parataxis	0.05,significantly
R3002	T9815	T9814	nsubj	P,0.05
R3003	T9816	T9814	punct	<,0.05
R3004	T9817	T9814	punct	),0.05
R3005	T9818	T9810	compound	rebleeding,time
R3006	T9819	T9810	punct	", ",time
R3007	T9820	T9821	dep	which,was
R3008	T9821	T9810	relcl	was,time
R3009	T9822	T9823	advmod	1.8-fold,lower
R3010	T9823	T9821	acomp	lower,was
R3011	T9824	T9823	prep	than,lower
R3012	T9825	T9824	prep	for,than
R3013	T9826	T9827	det	the,mice
R3014	T9827	T9825	pobj	mice,for
R3015	T9828	T9827	compound	B6,mice
R3016	T9829	T9808	punct	.,had
R3017	T9831	T9832	mark	Although,result
R3018	T9832	T9838	advcl	result,resulted
R3019	T9833	T9834	det	a,deficiency
R3020	T9834	T9832	nsubj	deficiency,result
R3021	T9835	T9834	compound	Plg,deficiency
R3022	T9836	T9832	aux	did,result
R3023	T9837	T9832	neg	not,result
R3024	T9839	T9832	prep	in,result
R3025	T9840	T9841	det	a,time
R3026	T9841	T9839	pobj	time,in
R3027	T9842	T9841	amod	prolonged,time
R3028	T9843	T9841	compound	rebleeding,time
R3029	T9844	T9845	mark	as,anticipated
R3030	T9845	T9832	advcl	anticipated,result
R3031	T9846	T9838	punct	", ",resulted
R3032	T9847	T9848	det	a,deficiency
R3033	T9848	T9838	nsubj	deficiency,resulted
R3034	T9849	T9848	nmod	PAI,deficiency
R3035	T9850	T9849	punct	-,PAI
R3036	T9851	T9849	nummod	1,PAI
R3037	T9852	T9838	prep	in,resulted
R3038	T9853	T9854	det	a,time
R3039	T9854	T9852	pobj	time,in
R3040	T9855	T9854	amod	shortened,time
R3041	T9856	T9838	punct	.,resulted
R3042	T9858	T9859	det	The,time
R3043	T9859	T9863	nsubj	time,suggest
R3044	T9860	T9861	advmod	markedly,increased
R3045	T9861	T9859	amod	increased,time
R3046	T9862	T9859	compound	rebleeding,time
R3047	T9864	T9859	prep	in,time
R3048	T9865	T9866	det	the,J
R3049	T9866	T9864	pobj	J,in
R3050	T9867	T9866	compound	A,J
R3051	T9868	T9866	punct	/,J
R3052	T9869	T9863	aux	may,suggest
R3053	T9870	T9863	dobj	differences,suggest
R3054	T9871	T9870	prep	in,differences
R3055	T9872	T9873	det	the,regulation
R3056	T9873	T9871	pobj	regulation,in
R3057	T9874	T9873	prep	of,regulation
R3058	T9875	T9876	det	the,network
R3059	T9876	T9874	pobj	network,of
R3060	T9877	T9876	compound	Plg,network
R3061	T9878	T9863	punct	.,suggest
R3068	T10215	T10216	det	No,difference
R3069	T10217	T10216	prep	in,difference
R3070	T10218	T10219	compound	blood,coagulation
R3071	T10219	T10217	pobj	coagulation,in
R3072	T10220	T10216	prep	between,difference
R3073	T10221	T10222	nmod	B6,mice
R3074	T10222	T10220	pobj	mice,between
R3075	T10223	T10221	cc	and,B6
R3076	T10224	T10225	compound	A,J
R3077	T10225	T10221	conj	J,B6
R3078	T10226	T10225	punct	/,J
R3079	T10228	T10229	aux	To,determine
R3080	T10229	T10230	advcl	determine,measured
R3081	T10231	T10232	mark	if,were
R3082	T10232	T10229	ccomp	were,determine
R3083	T10233	T10232	nsubj	differences,were
R3084	T10234	T10233	prep	in,differences
R3085	T10235	T10234	pobj	coagulation,in
R3086	T10236	T10237	amod	contributing,factors
R3087	T10237	T10232	attr	factors,were
R3088	T10238	T10237	prep	to,factors
R3089	T10239	T10240	det	the,results
R3090	T10240	T10238	pobj	results,to
R3091	T10241	T10240	nmod	bleeding,results
R3092	T10242	T10241	cc	and,bleeding
R3093	T10243	T10241	conj	rebleeding,bleeding
R3094	T10244	T10230	punct	", ",measured
R3095	T10245	T10246	compound	prothrombin,time
R3096	T10246	T10230	nsubjpass	time,measured
R3097	T10247	T10246	punct	(,time
R3098	T10248	T10246	appos	PT,time
R3099	T10249	T10246	punct	),time
R3100	T10250	T10246	cc	and,time
R3101	T10251	T10252	amod	activated,time
R3102	T10252	T10246	conj	time,time
R3103	T10253	T10252	amod	partial,time
R3104	T10254	T10252	compound	thromboplastin,time
R3105	T10255	T10252	punct	(,time
R3106	T10256	T10252	appos	aPTT,time
R3107	T10257	T10230	punct	),measured
R3108	T10258	T10230	auxpass	were,measured
R3109	T10259	T10230	punct	.,measured
R3110	T10261	T10262	nsubj	PT,is
R3111	T10263	T10264	det	a,measurement
R3112	T10264	T10262	attr	measurement,is
R3113	T10265	T10264	prep	of,measurement
R3114	T10266	T10267	det	the,pathway
R3115	T10267	T10265	pobj	pathway,of
R3116	T10268	T10267	amod	extrinsic,pathway
R3117	T10269	T10267	compound	coagulation,pathway
R3118	T10270	T10267	punct	(,pathway
R3119	T10271	T10267	appos	activation,pathway
R3120	T10272	T10271	prep	of,activation
R3121	T10273	T10272	pobj	Factor,of
R3122	T10274	T10273	nummod	VII,Factor
R3123	T10275	T10271	prep	by,activation
R3124	T10276	T10277	compound	tissue,factor
R3125	T10277	T10275	pobj	factor,by
R3126	T10278	T10262	punct	),is
R3127	T10279	T10280	mark	while,is
R3128	T10280	T10262	advcl	is,is
R3129	T10281	T10280	nsubj	aPTT,is
R3130	T10282	T10283	det	a,measurement
R3131	T10283	T10280	attr	measurement,is
R3132	T10284	T10283	prep	of,measurement
R3133	T10285	T10286	det	the,pathway
R3134	T10286	T10284	pobj	pathway,of
R3135	T10287	T10286	amod	intrinsic,pathway
R3136	T10288	T10286	punct	(,pathway
R3137	T10289	T10286	appos	activation,pathway
R3138	T10290	T10289	prep	of,activation
R3139	T10291	T10292	nmod	Factors,XII
R3140	T10292	T10290	pobj	XII,of
R3141	T10293	T10292	punct	", ",XII
R3142	T10294	T10292	conj	XI,XII
R3143	T10295	T10294	punct	", ",XI
R3144	T10296	T10294	conj	IX,XI
R3145	T10297	T10296	cc	and,IX
R3146	T10298	T10296	conj	VIII,IX
R3147	T10299	T10262	punct	),is
R3148	T10300	T10262	punct	.,is
R3149	T10302	T10303	det	The,products
R3150	T10303	T10304	nsubj	products,activate
R3151	T10305	T10303	prep	of,products
R3152	T10306	T10307	det	both,pathways
R3153	T10307	T10305	pobj	pathways,of
R3154	T10308	T10304	dobj	Factor,activate
R3155	T10309	T10308	nummod	X,Factor
R3156	T10310	T10308	punct	", ",Factor
R3157	T10311	T10312	dep	which,initiates
R3158	T10312	T10308	relcl	initiates,Factor
R3159	T10313	T10314	det	the,pathway
R3160	T10314	T10312	dobj	pathway,initiates
R3161	T10315	T10314	amod	common,pathway
R3162	T10316	T10314	acl	leading,pathway
R3163	T10317	T10316	prep	to,leading
R3164	T10318	T10319	compound	thrombin,generation
R3165	T10319	T10317	pobj	generation,to
R3166	T10320	T10319	cc	and,generation
R3167	T10321	T10322	compound	fibrin,clot
R3168	T10322	T10323	compound	clot,formation
R3169	T10323	T10319	conj	formation,generation
R3170	T10324	T10304	punct	.,activate
R3171	T10326	T10327	nsubjpass	PT,measured
R3172	T10328	T10326	cc	and,PT
R3173	T10329	T10326	conj	aPTT,PT
R3174	T10330	T10327	auxpass	were,measured
R3175	T10331	T10327	prep	in,measured
R3176	T10332	T10333	det	the,mice
R3177	T10333	T10331	pobj	mice,in
R3178	T10334	T10333	nmod	B6,mice
R3179	T10335	T10334	cc	and,B6
R3180	T10336	T10337	compound	A,J
R3181	T10337	T10334	conj	J,B6
R3182	T10338	T10337	punct	/,J
R3183	T10339	T10327	cc	and,measured
R3184	T10340	T10341	nsubj	values,were
R3185	T10341	T10327	conj	were,measured
R3186	T10342	T10341	neg	not,were
R3187	T10343	T10341	acomp	different,were
R3188	T10344	T10343	prep	between,different
R3189	T10345	T10346	det	the,strains
R3190	T10346	T10344	pobj	strains,between
R3191	T10347	T10346	nummod	two,strains
R3192	T10348	T10346	compound	mouse,strains
R3193	T10349	T10350	punct	(,Table
R3194	T10350	T10341	parataxis	Table,were
R3195	T10351	T10350	nummod	2,Table
R3196	T10352	T10350	punct	),Table
R3197	T10353	T10341	punct	.,were
R3198	T10355	T10356	det	These,results
R3199	T10356	T10357	nsubj	results,suggest
R3200	T10358	T10359	mark	that,is
R3201	T10359	T10357	ccomp	is,suggest
R3202	T10360	T10361	det	the,pathway
R3203	T10361	T10359	nsubj	pathway,is
R3204	T10362	T10361	compound	coagulation,pathway
R3205	T10363	T10359	neg	not,is
R3206	T10364	T10359	acomp	different,is
R3207	T10365	T10359	prep	in,is
R3208	T10366	T10367	det	the,strains
R3209	T10367	T10365	pobj	strains,in
R3210	T10368	T10367	nummod	two,strains
R3211	T10369	T10367	amod	inbred,strains
R3212	T10370	T10357	punct	.,suggest
R3213	T10951	T10952	nsubj	Plg,higher
R3214	T10953	T10951	cc	and,Plg
R3215	T10954	T10951	conj	PAI,Plg
R3216	T10955	T10954	punct	-,PAI
R3217	T10956	T10954	nummod	1,PAI
R3218	T10957	T10952	prep	in,higher
R3219	T10958	T10959	compound	A,J
R3220	T10959	T10957	pobj	J,in
R3221	T10960	T10959	punct	/,J
R3222	T10961	T10952	prep	than,higher
R3223	T10962	T10963	compound	B6,mice
R3224	T10963	T10961	pobj	mice,than
R3225	T10965	T10966	compound	Plg,concentration
R3226	T10966	T10967	nsubj	concentration,was
R3227	T10968	T10969	nummod	34,%
R3228	T10969	T10970	npadvmod	%,higher
R3229	T10970	T10967	acomp	higher,was
R3230	T10971	T10967	prep	in,was
R3231	T10972	T10973	det	the,mice
R3232	T10973	T10971	pobj	mice,in
R3233	T10974	T10975	compound	A,J
R3234	T10975	T10973	compound	J,mice
R3235	T10976	T10975	punct	/,J
R3236	T10977	T10967	prep	than,was
R3237	T10978	T10977	prep	in,than
R3238	T10979	T10980	compound	B6,mice
R3239	T10980	T10978	pobj	mice,in
R3240	T10981	T10967	punct	.,was
R3241	T10983	T10984	prep	In,increased
R3242	T10985	T10983	pobj	addition,In
R3243	T10986	T10984	punct	", ",increased
R3244	T10987	T10988	amod	fibrinolytic,activity
R3245	T10988	T10984	nsubjpass	activity,increased
R3246	T10989	T10988	punct	", ",activity
R3247	T10990	T10991	nmod	PAI,activity
R3248	T10991	T10988	conj	activity,activity
R3249	T10992	T10990	punct	-,PAI
R3250	T10993	T10990	nummod	1,PAI
R3251	T10994	T10991	punct	", ",activity
R3252	T10995	T10991	cc	and,activity
R3253	T10996	T10997	compound	α2,anitplasmin
R3254	T10997	T10991	conj	anitplasmin,activity
R3255	T10998	T10997	punct	-,anitplasmin
R3256	T10999	T10984	auxpass	were,increased
R3257	T11000	T10984	advmod	also,increased
R3258	T11001	T10984	prep	in,increased
R3259	T11002	T11003	det	the,mice
R3260	T11003	T11001	pobj	mice,in
R3261	T11004	T11005	nmod	A,J
R3262	T11005	T11003	compound	J,mice
R3263	T11006	T11005	punct	/,J
R3264	T11007	T11008	advmod	when,compared
R3265	T11008	T10984	advcl	compared,increased
R3266	T11009	T11008	prep	to,compared
R3267	T11010	T11011	det	the,mice
R3268	T11011	T11009	pobj	mice,to
R3269	T11012	T11011	compound	B6,mice
R3270	T11013	T11014	punct	(,Table
R3271	T11014	T10984	parataxis	Table,increased
R3272	T11015	T11014	nummod	2,Table
R3273	T11016	T11014	punct	),Table
R3274	T11017	T10984	punct	.,increased
R3275	T11019	T11020	det	The,consequences
R3276	T11020	T11022	nsubj	consequences,are
R3277	T11021	T11020	amod	functional,consequences
R3278	T11023	T11020	prep	of,consequences
R3279	T11024	T11025	det	these,differences
R3280	T11025	T11023	pobj	differences,of
R3281	T11026	T11022	neg	not,are
R3282	T11027	T11022	acomp	clear,are
R3283	T11028	T11022	punct	", ",are
R3284	T11029	T11030	mark	since,is
R3285	T11030	T11022	advcl	is,are
R3286	T11031	T11030	nsubj	fibrinogen,is
R3287	T11032	T11030	advmod	also,is
R3288	T11033	T11030	acomp	higher,is
R3289	T11034	T11030	prep	in,is
R3290	T11035	T11036	det	the,mice
R3291	T11036	T11034	pobj	mice,in
R3292	T11037	T11038	compound	A,J
R3293	T11038	T11036	compound	J,mice
R3294	T11039	T11038	punct	/,J
R3295	T11040	T11022	punct	.,are
R3296	T11042	T11043	aux	To,determine
R3297	T11043	T11044	advcl	determine,subjected
R3298	T11045	T11046	mark	whether,were
R3299	T11046	T11043	ccomp	were,determine
R3300	T11047	T11046	expl	there,were
R3301	T11048	T11049	compound	protein,structure
R3302	T11049	T11050	compound	structure,changes
R3303	T11050	T11046	attr	changes,were
R3304	T11051	T11050	prep	of,changes
R3305	T11052	T11051	pobj	Plg,of
R3306	T11053	T11050	prep	from,changes
R3307	T11054	T11055	det	the,mice
R3308	T11055	T11053	pobj	mice,from
R3309	T11056	T11057	compound	A,J
R3310	T11057	T11055	compound	J,mice
R3311	T11058	T11057	punct	/,J
R3312	T11059	T11044	punct	", ",subjected
R3313	T11060	T11044	nsubjpass	plasma,subjected
R3314	T11061	T11060	prep	from,plasma
R3315	T11062	T11063	det	the,B6
R3316	T11063	T11061	pobj	B6,from
R3317	T11064	T11063	cc	and,B6
R3318	T11065	T11066	det	the,J
R3319	T11066	T11069	compound	J,mice
R3320	T11067	T11066	compound	A,J
R3321	T11068	T11066	punct	/,J
R3322	T11069	T11063	conj	mice,B6
R3323	T11070	T11044	auxpass	were,subjected
R3324	T11071	T11044	prep	to,subjected
R3325	T11072	T11071	pobj	electrophoresis,to
R3326	T11073	T11044	prep	under,subjected
R3327	T11074	T11075	amod	reduced,conditions
R3328	T11075	T11073	pobj	conditions,under
R3329	T11076	T11074	punct	", ",reduced
R3330	T11077	T11074	conj	non-reduced,reduced
R3331	T11078	T11077	punct	", ",non-reduced
R3332	T11079	T11077	cc	and,non-reduced
R3333	T11080	T11077	conj	non-denaturing,non-reduced
R3334	T11081	T11044	punct	.,subjected
R3335	T11083	T11084	det	No,difference
R3336	T11084	T11085	nsubjpass	difference,observed
R3337	T11086	T11084	prep	in,difference
R3338	T11087	T11086	pobj	migration,in
R3339	T11088	T11084	prep	for,difference
R3340	T11089	T11090	amod	immunostained,Plg
R3341	T11090	T11088	pobj	Plg,for
R3342	T11091	T11084	prep	under,difference
R3343	T11092	T11093	det	these,conditions
R3344	T11093	T11091	pobj	conditions,under
R3345	T11094	T11085	auxpass	was,observed
R3346	T11095	T11096	punct	(,shown
R3347	T11096	T11085	parataxis	shown,observed
R3348	T11097	T11096	nsubj	data,shown
R3349	T11098	T11096	neg	not,shown
R3350	T11099	T11096	punct	),shown
R3351	T11100	T11085	punct	.,observed
R3352	T11102	T11103	det	The,density
R3353	T11103	T11104	nsubjpass	density,compared
R3354	T11105	T11103	prep	of,density
R3355	T11106	T11107	det	the,blot
R3356	T11107	T11105	pobj	blot,of
R3357	T11108	T11107	compound	Western,blot
R3358	T11109	T11107	prep	from,blot
R3359	T11110	T11111	compound	SDS,PAGE
R3360	T11111	T11109	pobj	PAGE,from
R3361	T11112	T11111	punct	-,PAGE
R3362	T11113	T11103	prep	under,density
R3363	T11114	T11115	compound	reducing,conditions
R3364	T11115	T11113	pobj	conditions,under
R3365	T11116	T11115	prep	of,conditions
R3366	T11117	T11116	pobj	plasma,of
R3367	T11118	T11117	prep	of,plasma
R3368	T11119	T11120	amod	varying,volumes
R3369	T11120	T11118	pobj	volumes,of
R3370	T11121	T11117	prep	from,plasma
R3371	T11122	T11123	nmod	B6,mice
R3372	T11123	T11121	pobj	mice,from
R3373	T11124	T11122	cc	and,B6
R3374	T11125	T11126	compound	A,J
R3375	T11126	T11122	conj	J,B6
R3376	T11127	T11126	punct	/,J
R3377	T11128	T11104	auxpass	was,compared
R3378	T11129	T11104	cc	and,compared
R3379	T11130	T11131	det	the,density
R3380	T11131	T11132	nsubj	density,was
R3381	T11132	T11104	conj	was,compared
R3382	T11133	T11131	prep	of,density
R3383	T11134	T11135	det	the,bands
R3384	T11135	T11133	pobj	bands,of
R3385	T11136	T11137	nummod	56,%
R3386	T11137	T11138	npadvmod	%,higher
R3387	T11138	T11132	acomp	higher,was
R3388	T11139	T11132	prep	in,was
R3389	T11140	T11141	det	the,J
R3390	T11141	T11139	pobj	J,in
R3391	T11142	T11141	compound	A,J
R3392	T11143	T11141	punct	/,J
R3393	T11144	T11132	prep	than,was
R3394	T11145	T11146	det	the,B6
R3395	T11146	T11144	pobj	B6,than
R3396	T11147	T11132	dobj	mice,was
R3397	T11148	T11149	punct	(,tested
R3398	T11149	T11132	parataxis	tested,was
R3399	T11150	T11151	nummod	six,mice
R3400	T11151	T11149	nsubjpass	mice,tested
R3401	T11152	T11151	amod	individual,mice
R3402	T11153	T11149	auxpass	were,tested
R3403	T11154	T11149	prep	on,tested
R3404	T11155	T11156	advmod	at,two
R3405	T11156	T11158	nummod	two,occasions
R3406	T11157	T11156	advmod	least,two
R3407	T11158	T11154	pobj	occasions,on
R3408	T11159	T11149	punct	),tested
R3409	T11160	T11132	prep	from,was
R3410	T11161	T11162	det	the,amount
R3411	T11162	T11160	pobj	amount,from
R3412	T11163	T11162	amod	same,amount
R3413	T11164	T11162	prep	of,amount
R3414	T11165	T11164	pobj	plasma,of
R3415	T11166	T11167	punct	(,1B
R3416	T11167	T11132	parataxis	1B,was
R3417	T11168	T11167	compound	Fig.,1B
R3418	T11169	T11167	punct	),1B
R3419	T11170	T11132	punct	.,was
R3420	T11172	T11173	advmod	Thus,was
R3421	T11174	T11173	punct	", ",was
R3422	T11175	T11176	det	the,concentration
R3423	T11176	T11173	nsubj	concentration,was
R3424	T11177	T11176	prep	of,concentration
R3425	T11178	T11177	pobj	Plg,of
R3426	T11179	T11176	prep	in,concentration
R3427	T11180	T11179	pobj	plasma,in
R3428	T11181	T11180	prep	from,plasma
R3429	T11182	T11183	det	the,mice
R3430	T11183	T11181	pobj	mice,from
R3431	T11184	T11185	compound	A,J
R3432	T11185	T11183	compound	J,mice
R3433	T11186	T11185	punct	/,J
R3434	T11187	T11173	acomp	higher,was
R3435	T11188	T11187	prep	than,higher
R3436	T11189	T11188	pobj	plasma,than
R3437	T11190	T11189	prep	from,plasma
R3438	T11191	T11192	det	the,mice
R3439	T11192	T11190	pobj	mice,from
R3440	T11193	T11192	compound	B6,mice
R3441	T11194	T11195	mark	as,determined
R3442	T11195	T11173	advcl	determined,was
R3443	T11196	T11195	prep	by,determined
R3444	T11197	T11198	nummod	two,methods
R3445	T11198	T11196	pobj	methods,by
R3446	T11199	T11173	cc	and,was
R3447	T11200	T11201	det	no,difference
R3448	T11201	T11202	nsubjpass	difference,observed
R3449	T11202	T11173	conj	observed,was
R3450	T11203	T11201	prep	in,difference
R3451	T11204	T11203	pobj	migration,in
R3452	T11205	T11201	prep	after,difference
R3453	T11206	T11205	pobj	electrophoresis,after
R3454	T11207	T11202	auxpass	was,observed
R3455	T11208	T11202	punct	", ",observed
R3456	T11209	T11202	advcl	suggesting,observed
R3457	T11210	T11211	det	no,changes
R3458	T11211	T11209	dobj	changes,suggesting
R3459	T11212	T11211	amod	marked,changes
R3460	T11213	T11211	prep	in,changes
R3461	T11214	T11215	det	the,structure
R3462	T11215	T11213	pobj	structure,in
R3463	T11216	T11215	prep	of,structure
R3464	T11217	T11216	pobj	Plg,of
R3465	T11218	T11211	prep	in,changes
R3466	T11219	T11220	det	the,strains
R3467	T11220	T11218	pobj	strains,in
R3468	T11221	T11220	nummod	two,strains
R3469	T11222	T11220	compound	mouse,strains
R3470	T11223	T11202	punct	.,observed
R3471	T11637	T11638	compound	Tail,morphology
R3472	T11639	T11638	prep	in,morphology
R3473	T11640	T11639	pobj	B6,in
R3474	T11641	T11640	cc	and,B6
R3475	T11642	T11643	compound	A,J
R3476	T11643	T11640	conj	J,B6
R3477	T11644	T11643	punct	/,J
R3478	T11646	T11647	det	The,tails
R3479	T11647	T11648	nsubjpass	tails,examined
R3480	T11649	T11647	prep	of,tails
R3481	T11650	T11651	det	the,mice
R3482	T11651	T11649	pobj	mice,of
R3483	T11652	T11648	auxpass	were,examined
R3484	T11653	T11648	prep	for,examined
R3485	T11654	T11653	pobj	differences,for
R3486	T11655	T11656	dep	that,account
R3487	T11656	T11654	relcl	account,differences
R3488	T11657	T11656	aux	might,account
R3489	T11658	T11656	prep	for,account
R3490	T11659	T11660	det	the,variations
R3491	T11660	T11658	pobj	variations,for
R3492	T11661	T11660	prep	in,variations
R3493	T11662	T11663	det	the,values
R3494	T11663	T11661	pobj	values,in
R3495	T11664	T11663	nmod	bleeding,values
R3496	T11665	T11664	cc	and,bleeding
R3497	T11666	T11664	conj	rebleeding,bleeding
R3498	T11667	T11648	punct	.,examined
R3499	T11669	T11670	nsubjpass	Sections,stained
R3500	T11671	T11669	prep	of,Sections
R3501	T11672	T11673	det	the,tail
R3502	T11673	T11671	pobj	tail,of
R3503	T11674	T11673	prep	from,tail
R3504	T11675	T11676	det	the,mice
R3505	T11676	T11674	pobj	mice,from
R3506	T11677	T11676	nmod	B6,mice
R3507	T11678	T11677	cc	and,B6
R3508	T11679	T11680	compound	A,J
R3509	T11680	T11677	conj	J,B6
R3510	T11681	T11680	punct	/,J
R3511	T11682	T11670	auxpass	were,stained
R3512	T11683	T11670	prep	with,stained
R3513	T11684	T11685	compound	Hematoxylin,Eosin
R3514	T11685	T11683	pobj	Eosin,with
R3515	T11686	T11685	punct	/,Eosin
R3516	T11687	T11685	cc	or,Eosin
R3517	T11688	T11689	poss	Masson,Trichrome
R3518	T11689	T11685	conj	Trichrome,Eosin
R3519	T11690	T11688	case	's,Masson
R3520	T11691	T11670	cc	and,stained
R3521	T11692	T11693	amod	representative,sections
R3522	T11693	T11694	nsubjpass	sections,shown
R3523	T11694	T11670	conj	shown,stained
R3524	T11695	T11694	auxpass	are,shown
R3525	T11696	T11694	prep	in,shown
R3526	T11697	T11696	pobj	Figure,in
R3527	T11698	T11697	nummod	3,Figure
R3528	T11699	T11694	punct	.,shown
R3529	T11701	T11702	det	No,differences
R3530	T11702	T11705	nsubjpass	differences,observed
R3531	T11703	T11702	amod	obvious,differences
R3532	T11704	T11702	amod	qualitative,differences
R3533	T11706	T11705	auxpass	were,observed
R3534	T11707	T11705	prep	in,observed
R3535	T11708	T11709	compound	hair,follicles
R3536	T11709	T11707	pobj	follicles,in
R3537	T11710	T11709	punct	", ",follicles
R3538	T11711	T11712	amod	sebaceous,glands
R3539	T11712	T11709	conj	glands,follicles
R3540	T11713	T11712	punct	", ",glands
R3541	T11714	T11712	cc	or,glands
R3542	T11715	T11716	compound	center,bone
R3543	T11716	T11712	conj	bone,glands
R3544	T11717	T11716	punct	/,bone
R3545	T11718	T11716	appos	cartilage,bone
R3546	T11719	T11705	prep	in,observed
R3547	T11720	T11721	compound	Hematoxylin,Eosin
R3548	T11721	T11723	npadvmod	Eosin,stained
R3549	T11722	T11721	punct	/,Eosin
R3550	T11723	T11728	amod	stained,sections
R3551	T11724	T11725	punct	(,3A
R3552	T11725	T11721	parataxis	3A,Eosin
R3553	T11726	T11725	compound	Figure,3A
R3554	T11727	T11725	punct	),3A
R3555	T11728	T11719	pobj	sections,in
R3556	T11729	T11705	punct	.,observed
R3557	T11731	T11732	nsubjpass	Sections,stained
R3558	T11733	T11731	prep	of,Sections
R3559	T11734	T11735	det	the,tails
R3560	T11735	T11733	pobj	tails,of
R3561	T11736	T11732	auxpass	were,stained
R3562	T11737	T11732	prep	with,stained
R3563	T11738	T11739	poss	Masson,Trichrome
R3564	T11739	T11737	pobj	Trichrome,with
R3565	T11740	T11738	case	's,Masson
R3566	T11741	T11742	punct	(,3B
R3567	T11742	T11739	parataxis	3B,Trichrome
R3568	T11743	T11742	compound	Figure,3B
R3569	T11744	T11742	punct	),3B
R3570	T11745	T11746	dep	that,detects
R3571	T11746	T11739	relcl	detects,Trichrome
R3572	T11747	T11746	dobj	collagen,detects
R3573	T11748	T11747	punct	", ",collagen
R3574	T11749	T11750	det	the,substratum
R3575	T11750	T11747	appos	substratum,collagen
R3576	T11751	T11750	amod	major,substratum
R3577	T11752	T11750	nmod	platelet,substratum
R3578	T11753	T11752	amod	adhesive,platelet
R3579	T11754	T11750	prep	for,substratum
R3580	T11755	T11754	pobj	initiation,for
R3581	T11756	T11755	prep	of,initiation
R3582	T11757	T11758	compound	thrombus,formation
R3583	T11758	T11756	pobj	formation,of
R3584	T11759	T11732	punct	.,stained
R3585	T11761	T11762	compound	Collagen,content
R3586	T11762	T11763	nsubjpass	content,quantified
R3587	T11764	T11765	punct	(,area
R3588	T11765	T11762	parataxis	area,content
R3589	T11766	T11765	compound	%,area
R3590	T11767	T11765	compound	tail,area
R3591	T11768	T11765	punct	),area
R3592	T11769	T11763	auxpass	was,quantified
R3593	T11770	T11771	punct	(,3C
R3594	T11771	T11763	parataxis	3C,quantified
R3595	T11772	T11771	compound	Figure,3C
R3596	T11773	T11771	punct	),3C
R3597	T11774	T11763	prep	from,quantified
R3598	T11775	T11776	quantmod	3,4
R3599	T11776	T11778	nummod	4,sections
R3600	T11777	T11776	punct	–,4
R3601	T11778	T11774	pobj	sections,from
R3602	T11779	T11778	prep	from,sections
R3603	T11780	T11781	quantmod	2,3
R3604	T11781	T11783	nummod	3,areas
R3605	T11782	T11781	punct	–,3
R3606	T11783	T11779	pobj	areas,from
R3607	T11784	T11785	punct	/,mouse
R3608	T11785	T11783	prep	mouse,areas
R3609	T11786	T11763	punct	.,quantified
R3610	T11788	T11789	det	The,amount
R3611	T11789	T11790	nsubj	amount,was
R3612	T11791	T11789	prep	of,amount
R3613	T11792	T11791	pobj	collagen,of
R3614	T11793	T11790	acomp	greater,was
R3615	T11794	T11790	prep	in,was
R3616	T11795	T11796	det	the,J
R3617	T11796	T11794	pobj	J,in
R3618	T11797	T11796	compound	A,J
R3619	T11798	T11796	punct	/,J
R3620	T11799	T11790	prep	than,was
R3621	T11800	T11801	det	the,mice
R3622	T11801	T11799	pobj	mice,than
R3623	T11802	T11801	compound	B6,mice
R3624	T11803	T11804	punct	(,0.05
R3625	T11804	T11790	parataxis	0.05,was
R3626	T11805	T11804	nsubj	P,0.05
R3627	T11806	T11804	punct	<,0.05
R3628	T11807	T11804	punct	),0.05
R3629	T11808	T11790	punct	.,was
R3630	T11810	T11811	nsubjpass	Collagen,increased
R3631	T11812	T11810	prep	in,Collagen
R3632	T11813	T11812	pobj	vessels,in
R3633	T11814	T11813	prep	in,vessels
R3634	T11815	T11816	compound	adipose,tissue
R3635	T11816	T11814	pobj	tissue,in
R3636	T11817	T11816	prep	in,tissue
R3637	T11818	T11819	det	the,mice
R3638	T11819	T11817	pobj	mice,in
R3639	T11820	T11821	compound	A,J
R3640	T11821	T11819	compound	J,mice
R3641	T11822	T11821	punct	/,J
R3642	T11823	T11811	auxpass	is,increased
R3643	T11824	T11811	advmod	also,increased
R3644	T11825	T11811	prep	compared,increased
R3645	T11826	T11825	prep	to,compared
R3646	T11827	T11828	det	the,mice
R3647	T11828	T11826	pobj	mice,to
R3648	T11829	T11828	compound	B6,mice
R3649	T11830	T11831	punct	(,shown
R3650	T11831	T11811	parataxis	shown,increased
R3651	T11832	T11831	nsubj	data,shown
R3652	T11833	T11831	neg	not,shown
R3653	T11834	T11831	punct	),shown
R3654	T11835	T11811	punct	.,increased
R3655	T12715	T12716	compound	Tail,bleeding
R3656	T12716	T12717	compound	bleeding,assay
R3657	T12717	T12718	nsubj	assay,identifies
R3658	T12719	T12720	nummod	three,chromosomes
R3659	T12720	T12718	dobj	chromosomes,identifies
R3660	T12721	T12720	prep	with,chromosomes
R3661	T12722	T12721	pobj	QTL,with
R3662	T12723	T12722	prep	for,QTL
R3663	T12724	T12723	pobj	rebleeding,for
R3664	T12725	T12718	prep	in,identifies
R3665	T12726	T12725	pobj	CSS,in
R3666	T12728	T12729	advcl	Using,screened
R3667	T12730	T12731	det	the,assay
R3668	T12731	T12728	dobj	assay,Using
R3669	T12732	T12733	compound	tail,rebleeding
R3670	T12733	T12731	compound	rebleeding,assay
R3671	T12734	T12733	compound	bleeding,rebleeding
R3672	T12735	T12733	punct	/,rebleeding
R3673	T12736	T12728	prep	as,Using
R3674	T12737	T12738	det	a,marker
R3675	T12738	T12736	pobj	marker,as
R3676	T12739	T12738	amod	surrogate,marker
R3677	T12740	T12738	prep	for,marker
R3678	T12741	T12740	pobj	hemostasis,for
R3679	T12742	T12741	cc	and,hemostasis
R3680	T12743	T12741	conj	thrombosis,hemostasis
R3681	T12744	T12729	punct	", ",screened
R3682	T12745	T12746	det	the,CSS
R3683	T12746	T12729	nsubjpass	CSS,screened
R3684	T12747	T12729	auxpass	were,screened
R3685	T12748	T12729	punct	.,screened
R3686	T12750	T12751	det	The,times
R3687	T12751	T12753	nsubj	times,were
R3688	T12752	T12751	compound	bleeding,times
R3689	T12754	T12755	punct	(,4A
R3690	T12755	T12751	parataxis	4A,times
R3691	T12756	T12755	compound	Figure,4A
R3692	T12757	T12755	punct	),4A
R3693	T12758	T12751	prep	for,times
R3694	T12759	T12760	det	the,B6
R3695	T12760	T12758	pobj	B6,for
R3696	T12761	T12760	cc	and,B6
R3697	T12762	T12763	det	the,J
R3698	T12763	T12766	compound	J,mice
R3699	T12764	T12763	compound	A,J
R3700	T12765	T12763	punct	/,J
R3701	T12766	T12760	conj	mice,B6
R3702	T12767	T12753	neg	not,were
R3703	T12768	T12753	acomp	different,were
R3704	T12769	T12753	punct	", ",were
R3705	T12770	T12753	cc	but,were
R3706	T12771	T12772	nsubj	6six,had
R3707	T12772	T12753	conj	had,were
R3708	T12773	T12771	prep	of,6six
R3709	T12774	T12775	det	the,strains
R3710	T12775	T12773	pobj	strains,of
R3711	T12776	T12771	punct	", ",6six
R3712	T12777	T12778	compound	B6,Chr5
R3713	T12778	T12771	appos	Chr5,6six
R3714	T12779	T12778	punct	-,Chr5
R3715	T12780	T12778	punct	", ",Chr5
R3716	T12781	T12778	conj	6,Chr5
R3717	T12782	T12781	punct	", ",6
R3718	T12783	T12781	conj	8,6
R3719	T12784	T12783	punct	", ",8
R3720	T12785	T12783	conj	14,8
R3721	T12786	T12785	punct	", ",14
R3722	T12787	T12785	conj	15,14
R3723	T12788	T12787	punct	", ",15
R3724	T12789	T12787	cc	and,15
R3725	T12790	T12791	compound	YA,J
R3726	T12791	T12787	conj	J,15
R3727	T12792	T12791	punct	/,J
R3728	T12793	T12772	punct	", ",had
R3729	T12794	T12795	amod	lower,times
R3730	T12795	T12772	dobj	times,had
R3731	T12796	T12797	punct	(,0.002
R3732	T12797	T12794	parataxis	0.002,lower
R3733	T12798	T12797	nsubj	P,0.002
R3734	T12799	T12797	punct	<,0.002
R3735	T12800	T12797	punct	),0.002
R3736	T12801	T12795	compound	bleeding,times
R3737	T12802	T12795	punct	(,times
R3738	T12803	T12804	quantmod	49,79
R3739	T12804	T12806	nummod	79,seconds
R3740	T12805	T12804	punct	–,79
R3741	T12806	T12795	appos	seconds,times
R3742	T12807	T12772	punct	),had
R3743	T12808	T12772	prep	compared,had
R3744	T12809	T12808	prep	to,compared
R3745	T12810	T12811	det	the,value
R3746	T12811	T12809	pobj	value,to
R3747	T12812	T12811	prep	for,value
R3748	T12813	T12814	det	the,mice
R3749	T12814	T12812	pobj	mice,for
R3750	T12815	T12814	compound	B6,mice
R3751	T12816	T12811	punct	(,value
R3752	T12817	T12818	nummod	121,sec
R3753	T12818	T12811	appos	sec,value
R3754	T12819	T12772	punct	),had
R3755	T12820	T12772	punct	.,had
R3756	T12822	T12823	det	The,time
R3757	T12823	T12825	nsubjpass	time,increased
R3758	T12824	T12823	compound	rebleeding,time
R3759	T12826	T12827	punct	(,4B
R3760	T12827	T12823	parataxis	4B,time
R3761	T12828	T12827	compound	Figure,4B
R3762	T12829	T12827	punct	),4B
R3763	T12830	T12823	punct	", ",time
R3764	T12831	T12823	acl	determined,time
R3765	T12832	T12831	prep	as,determined
R3766	T12833	T12834	det	the,time
R3767	T12834	T12832	pobj	time,as
R3768	T12835	T12834	prep	between,time
R3769	T12836	T12837	compound	bleeding,cessation
R3770	T12837	T12835	pobj	cessation,between
R3771	T12838	T12837	cc	and,cessation
R3772	T12839	T12837	conj	initiation,cessation
R3773	T12840	T12839	prep	of,initiation
R3774	T12841	T12842	det	the,bleeding
R3775	T12842	T12840	pobj	bleeding,of
R3776	T12843	T12842	amod	second,bleeding
R3777	T12844	T12825	punct	", ",increased
R3778	T12845	T12825	auxpass	was,increased
R3779	T12846	T12825	advmod	markedly,increased
R3780	T12847	T12825	prep	in,increased
R3781	T12848	T12849	det	the,mice
R3782	T12849	T12847	pobj	mice,in
R3783	T12850	T12851	compound	A,J
R3784	T12851	T12849	compound	J,mice
R3785	T12852	T12851	punct	/,J
R3786	T12853	T12825	prep	compared,increased
R3787	T12854	T12853	prep	to,compared
R3788	T12855	T12856	det	the,mice
R3789	T12856	T12854	pobj	mice,to
R3790	T12857	T12856	compound	B6,mice
R3791	T12858	T12825	cc	and,increased
R3792	T12859	T12860	nummod	two,strains
R3793	T12860	T12861	nsubj	strains,had
R3794	T12861	T12825	conj	had,increased
R3795	T12862	T12860	punct	", ",strains
R3796	T12863	T12864	compound	B6,Chr11A
R3797	T12864	T12866	compound	Chr11A,J
R3798	T12865	T12864	punct	-,Chr11A
R3799	T12866	T12860	appos	J,strains
R3800	T12867	T12866	punct	/,J
R3801	T12868	T12866	punct	(,J
R3802	T12869	T12866	appos	CSS,J
R3803	T12870	T12869	punct	-,CSS
R3804	T12871	T12869	nummod	11,CSS
R3805	T12872	T12866	punct	),J
R3806	T12873	T12866	cc	and,J
R3807	T12874	T12875	compound	B6,Chr17A
R3808	T12875	T12877	compound	Chr17A,J
R3809	T12876	T12875	punct	-,Chr17A
R3810	T12877	T12866	conj	J,J
R3811	T12878	T12877	punct	/,J
R3812	T12879	T12877	punct	(,J
R3813	T12880	T12877	appos	CSS,J
R3814	T12881	T12880	punct	-,CSS
R3815	T12882	T12880	nummod	17,CSS
R3816	T12883	T12861	punct	),had
R3817	T12884	T12861	punct	", ",had
R3818	T12885	T12886	advmod	significantly,longer
R3819	T12886	T12892	amod	longer,times
R3820	T12887	T12888	punct	(,0.002
R3821	T12888	T12885	parataxis	0.002,significantly
R3822	T12889	T12888	nsubj	P,0.002
R3823	T12890	T12888	punct	<,0.002
R3824	T12891	T12888	punct	),0.002
R3825	T12892	T12861	dobj	times,had
R3826	T12893	T12892	compound	rebleeding,times
R3827	T12894	T12861	prep	compared,had
R3828	T12895	T12894	prep	to,compared
R3829	T12896	T12897	det	the,mice
R3830	T12897	T12895	pobj	mice,to
R3831	T12898	T12897	compound	B6,mice
R3832	T12899	T12900	dep	that,were
R3833	T12900	T12897	relcl	were,mice
R3834	T12901	T12900	acomp	similar,were
R3835	T12902	T12901	prep	to,similar
R3836	T12903	T12902	pobj	values,to
R3837	T12904	T12903	prep	from,values
R3838	T12905	T12906	det	the,mice
R3839	T12906	T12904	pobj	mice,from
R3840	T12907	T12908	compound	A,J
R3841	T12908	T12906	compound	J,mice
R3842	T12909	T12908	punct	/,J
R3843	T12910	T12861	punct	.,had
R3844	T12912	T12913	det	Another,strain
R3845	T12913	T12914	nsubj	strain,approached
R3846	T12915	T12913	punct	", ",strain
R3847	T12916	T12917	compound	B6,Chr5A
R3848	T12917	T12919	compound	Chr5A,J
R3849	T12918	T12917	punct	-,Chr5A
R3850	T12919	T12913	appos	J,strain
R3851	T12920	T12919	punct	/,J
R3852	T12921	T12919	punct	(,J
R3853	T12922	T12919	appos	CSS,J
R3854	T12923	T12922	punct	-,CSS
R3855	T12924	T12922	nummod	5,CSS
R3856	T12925	T12914	punct	),approached
R3857	T12926	T12914	punct	", ",approached
R3858	T12927	T12914	dobj	significance,approached
R3859	T12928	T12914	prep	at,approached
R3860	T12929	T12928	pobj	P,at
R3861	T12930	T12931	punct	<,0.008
R3862	T12931	T12929	amod	0.008,P
R3863	T12932	T12914	punct	.,approached
R3864	T12934	T12935	det	The,time
R3865	T12935	T12937	nsubjpass	time,stopped
R3866	T12936	T12935	compound	rebleeding,time
R3867	T12938	T12937	auxpass	was,stopped
R3868	T12939	T12937	prep	at,stopped
R3869	T12940	T12941	nummod	600,sec
R3870	T12941	T12939	pobj	sec,at
R3871	T12942	T12937	punct	", ",stopped
R3872	T12943	T12937	cc	and,stopped
R3873	T12944	T12945	det	the,percentage
R3874	T12945	T12946	nsubj	percentage,determined
R3875	T12946	T12937	conj	determined,stopped
R3876	T12947	T12945	prep	of,percentage
R3877	T12948	T12947	pobj	mice,of
R3878	T12949	T12948	prep	with,mice
R3879	T12950	T12951	det	this,value
R3880	T12951	T12949	pobj	value,with
R3881	T12952	T12946	prep	for,determined
R3882	T12953	T12954	det	the,strains
R3883	T12954	T12952	pobj	strains,for
R3884	T12955	T12954	nummod	three,strains
R3885	T12956	T12937	punct	: ,stopped
R3886	T12957	T12958	dep	CSS,%
R3887	T12958	T12937	dep	%,stopped
R3888	T12959	T12957	punct	-,CSS
R3889	T12960	T12957	nummod	5,CSS
R3890	T12961	T12958	punct	–,%
R3891	T12962	T12958	nummod	60,%
R3892	T12963	T12958	punct	", ",%
R3893	T12964	T12965	dep	CSS,%
R3894	T12965	T12958	conj	%,%
R3895	T12966	T12964	punct	-,CSS
R3896	T12967	T12964	nummod	11,CSS
R3897	T12968	T12965	punct	–,%
R3898	T12969	T12965	compound	60,%
R3965	T13040	T13038	punct	-,CSS
R3966	T13041	T13038	nummod	5,CSS
R3967	T13042	T13038	punct	", ",CSS
R3968	T13043	T13038	punct	(,CSS
R3969	T13044	T13038	appos	B6xCSS,CSS
R3970	T13045	T13044	punct	-,B6xCSS
R3971	T13046	T13044	nummod	5,B6xCSS
R3972	T13047	T13039	punct	),F1
R3973	T13048	T13039	cc	and,F1
R3974	T13049	T13050	nmod	CSS,F1
R3975	T13050	T13039	conj	F1,F1
R3976	T13051	T13049	punct	-,CSS
R3977	T13052	T13049	nummod	17,CSS
R3978	T13053	T13049	punct	(,CSS
R3979	T13054	T13049	appos	B6xCSS,CSS
R3980	T13055	T13054	punct	-,B6xCSS
R3981	T13056	T13054	nummod	17,B6xCSS
R3982	T13057	T13050	punct	),F1
R3983	T13058	T13059	punct	(,Figure
R3984	T13059	T13032	parataxis	Figure,produce
R3985	T13060	T13059	nummod	5,Figure
R3986	T13061	T13059	punct	),Figure
R3987	T13062	T13010	punct	.,compared
R3988	T13064	T13065	det	The,values
R3989	T13065	T13067	nsubj	values,were
R3990	T13066	T13065	compound	rebleeding,values
R3991	T13068	T13065	prep	for,values
R3992	T13069	T13070	nmod	CSS,5F1
R3993	T13070	T13072	nmod	5F1,mice
R3994	T13071	T13070	punct	-,5F1
R3995	T13072	T13068	pobj	mice,for
R3996	T13073	T13070	cc	and,5F1
R3997	T13074	T13075	compound	CSS,17F1
R3998	T13075	T13070	conj	17F1,5F1
R3999	T13076	T13075	punct	-,17F1
R4000	T13077	T13067	acomp	similar,were
R4001	T13078	T13077	prep	to,similar
R4002	T13079	T13080	det	the,B6
R4003	T13080	T13078	pobj	B6,to
R4004	T13081	T13082	advmod	rather,than
R4005	T13082	T13080	cc	than,B6
R4006	T13083	T13084	det	the,J
R4007	T13084	T13087	compound	J,mice
R4008	T13085	T13084	compound	A,J
R4009	T13086	T13084	punct	/,J
R4010	T13087	T13080	conj	mice,B6
R4011	T13088	T13067	punct	", ",were
R4012	T13089	T13067	advcl	suggesting,were
R4013	T13090	T13091	det	the,trait
R4014	T13091	T13095	nsubj	trait,is
R4015	T13092	T13093	compound	A,J
R4016	T13093	T13091	compound	J,trait
R4017	T13094	T13093	punct	/,J
R4018	T13095	T13089	advcl	is,suggesting
R4019	T13096	T13095	acomp	recessive,is
R4020	T13097	T13067	punct	.,were
R4021	T13099	T13100	nsubj	Bleeding,resulted
R4022	T13101	T13099	cc	and,Bleeding
R4023	T13102	T13099	conj	rebleeding,Bleeding
R4024	T13103	T13099	prep	in,Bleeding
R4025	T13104	T13105	det	the,progeny
R4026	T13105	T13103	pobj	progeny,in
R4027	T13106	T13105	prep	of,progeny
R4028	T13107	T13108	det	the,cross
R4029	T13108	T13106	pobj	cross,of
R4030	T13109	T13108	punct	", ",cross
R4031	T13110	T13111	compound	B6,J
R4032	T13111	T13108	appos	J,cross
R4033	T13112	T13111	punct	-,J
R4034	T13113	T13111	compound	Chr5A,J
R4035	T13114	T13111	punct	/,J
R4036	T13115	T13111	punct	×,J
R4037	T13116	T13117	compound	B6,J
R4038	T13117	T13111	appos	J,J
R4039	T13118	T13117	punct	-,J
R4040	T13119	T13117	compound	Chr17A,J
R4041	T13120	T13117	punct	/,J
R4042	T13121	T13111	punct	(,J
R4043	T13122	T13111	appos	CSS,J
R4044	T13123	T13122	punct	-,CSS
R4045	T13124	T13122	nummod	5,CSS
R4046	T13125	T13122	punct	×,CSS
R4047	T13126	T13122	appos	CSS,CSS
R4048	T13127	T13126	punct	-,CSS
R4049	T13128	T13126	nummod	17,CSS
R4050	T13129	T13100	punct	),resulted
R4051	T13130	T13100	prep	in,resulted
R4052	T13131	T13132	det	the,recovery
R4053	T13132	T13130	pobj	recovery,in
R4054	T13133	T13132	prep	of,recovery
R4055	T13134	T13135	det	the,phenotype
R4056	T13135	T13133	pobj	phenotype,of
R4057	T13136	T13137	compound	A,J
R4058	T13137	T13135	compound	J,phenotype
R4059	T13138	T13137	punct	/,J
R4060	T13139	T13132	prep	in,recovery
R4061	T13140	T13141	det	the,progeny
R4062	T13141	T13139	pobj	progeny,in
R4063	T13142	T13141	prep	of,progeny
R4064	T13143	T13144	det	these,strains
R4065	T13144	T13142	pobj	strains,of
R4066	T13145	T13146	amod	double,heterosomic
R4067	T13146	T13144	amod	heterosomic,strains
R4068	T13147	T13100	punct	.,resulted
R4069	T13149	T13150	advmod	Thus,was
R4070	T13151	T13150	punct	", ",was
R4071	T13152	T13150	prep	despite,was
R4072	T13153	T13154	det	the,chromosomes
R4073	T13154	T13152	pobj	chromosomes,despite
R4074	T13155	T13154	amod	heterosomic,chromosomes
R4075	T13156	T13154	prep	of,chromosomes
R4076	T13157	T13156	pobj	5,of
R4077	T13158	T13157	cc	and,5
R4078	T13159	T13157	conj	17,5
R4079	T13160	T13154	prep	in,chromosomes
R4080	T13161	T13162	det	the,progeny
R4081	T13162	T13160	pobj	progeny,in
R4082	T13163	T13162	prep	of,progeny
R4083	T13164	T13165	det	the,CSS
R4084	T13165	T13163	pobj	CSS,of
R4085	T13166	T13165	punct	-,CSS
R4086	T13167	T13165	nummod	5,CSS
R4087	T13168	T13165	punct	×,CSS
R4088	T13169	T13165	appos	CSS,CSS
R4089	T13170	T13169	punct	-,CSS
R4090	T13171	T13169	nummod	17,CSS
R4091	T13172	T13150	punct	", ",was
R4092	T13173	T13174	det	the,phenotype
R4093	T13174	T13150	nsubj	phenotype,was
R4094	T13175	T13150	advmod	now,was
R4095	T13176	T13150	acomp	similar,was
R4096	T13177	T13176	prep	to,similar
R4097	T13178	T13179	compound	A,J
R4098	T13179	T13177	pobj	J,to
R4099	T13180	T13179	punct	/,J
R4100	T13181	T13150	punct	.,was
R4101	T13183	T13184	nsubj	This,suggested
R4102	T13185	T13186	mark	that,interacting
R4103	T13186	T13184	ccomp	interacting,suggested
R4104	T13187	T13186	nsubj	traits,interacting
R4105	T13188	T13187	prep	on,traits
R4106	T13189	T13190	det	the,chromosomes
R4107	T13190	T13188	pobj	chromosomes,on
R4108	T13191	T13192	compound	A,J
R4109	T13192	T13190	compound	J,chromosomes
R4110	T13193	T13192	punct	/,J
R4111	T13194	T13186	aux	were,interacting
R4112	T13195	T13196	aux	to,produce
R4113	T13196	T13186	advcl	produce,interacting
R4114	T13197	T13198	det	the,phenotype
R4115	T13198	T13196	dobj	phenotype,produce
R4116	T13199	T13184	punct	.,suggested
R4117	T14100	T14099	prep	of,Interactions
R4118	T14101	T14100	pobj	CSS,of
R4119	T14102	T14099	prep	for,Interactions
R4120	T14103	T14102	pobj	PAI,for
R4121	T14104	T14103	punct	-,PAI
R4122	T14105	T14103	nummod	1,PAI
R4123	T14106	T14103	appos	antigen,PAI
R4124	T14107	T14106	cc	and,antigen
R4125	T14108	T14106	conj	activity,antigen
R4126	T14110	T14111	nsubj	Components,reside
R4127	T14112	T14110	prep	of,Components
R4128	T14113	T14114	det	the,system
R4129	T14114	T14112	pobj	system,of
R4130	T14115	T14114	compound	Plg,system
R4131	T14116	T14111	prep	on,reside
R4132	T14117	T14118	compound	chromosomes,CSS
R4133	T14118	T14116	pobj	CSS,on
R4134	T14119	T14118	punct	-,CSS
R4135	T14120	T14118	nummod	5,CSS
R4136	T14121	T14118	punct	(,CSS
R4137	T14122	T14118	appos	PAI,CSS
R4138	T14123	T14122	punct	-,PAI
R4139	T14124	T14122	nummod	1,PAI
R4140	T14125	T14118	punct	),CSS
R4141	T14126	T14118	punct	", ",CSS
R4142	T14127	T14118	conj	CSS,CSS
R4143	T14128	T14127	punct	-,CSS
R4144	T14129	T14127	nummod	11,CSS
R4145	T14130	T14127	punct	(,CSS
R4146	T14131	T14132	compound	α2,antiplasmin
R4147	T14132	T14127	appos	antiplasmin,CSS
R4148	T14133	T14132	punct	-,antiplasmin
R4149	T14134	T14127	punct	),CSS
R4150	T14135	T14127	punct	", ",CSS
R4151	T14136	T14127	cc	and,CSS
R4152	T14137	T14127	conj	CSS,CSS
R4153	T14138	T14137	punct	-,CSS
R4154	T14139	T14137	nummod	17,CSS
R4155	T14140	T14137	punct	(,CSS
R4156	T14141	T14137	appos	Plg,CSS
R4157	T14142	T14111	punct	),reside
R4158	T14143	T14111	punct	.,reside
R4159	T14145	T14146	mark	As,reported
R4160	T14146	T14147	advcl	reported,had
R4161	T14148	T14146	prep	in,reported
R4162	T14149	T14148	pobj	Table,in
R4163	T14150	T14149	nummod	2,Table
R4164	T14151	T14147	punct	", ",had
R4165	T14152	T14153	det	the,mice
R4166	T14153	T14147	nsubj	mice,had
R4167	T14154	T14155	compound	A,J
R4168	T14155	T14153	compound	J,mice
R4169	T14156	T14155	punct	/,J
R4170	T14157	T14158	amod	increased,antigen
R4171	T14158	T14147	dobj	antigen,had
R4172	T14159	T14158	compound	Plg,antigen
R4173	T14160	T14158	punct	", ",antigen
R4174	T14161	T14162	amod	fibrinolytic,activity
R4175	T14162	T14158	conj	activity,antigen
R4176	T14163	T14162	punct	", ",activity
R4177	T14164	T14165	compound	α2,antiplasmin
R4178	T14165	T14162	conj	antiplasmin,activity
R4179	T14166	T14165	punct	-,antiplasmin
R4180	T14167	T14165	punct	", ",antiplasmin
R4181	T14168	T14169	nmod	PAI,activity
R4182	T14169	T14165	conj	activity,antiplasmin
R4183	T14170	T14168	punct	-,PAI
R4184	T14171	T14168	nummod	1,PAI
R4185	T14172	T14169	cc	and,activity
R4186	T14173	T14169	conj	fibrinogen,activity
R4187	T14174	T14175	advmod	when,compared
R4188	T14175	T14147	advcl	compared,had
R4189	T14176	T14175	prep	to,compared
R4190	T14177	T14178	compound	B6,mice
R4191	T14178	T14176	pobj	mice,to
R4192	T14179	T14147	punct	.,had
R4193	T14181	T14182	prep	In,was
R4194	T14183	T14184	nmod	CSS,mice
R4195	T14184	T14181	pobj	mice,In
R4196	T14185	T14183	punct	-,CSS
R4197	T14186	T14183	nummod	17,CSS
R4198	T14187	T14182	punct	", ",was
R4199	T14188	T14189	det	the,antigen
R4200	T14189	T14182	nsubj	antigen,was
R4201	T14190	T14189	compound	Plg,antigen
R4202	T14191	T14182	advmod	also,was
R4203	T14192	T14193	advmod	significantly,increased
R4204	T14193	T14182	acomp	increased,was
R4205	T14194	T14195	punct	(,0.015
R4206	T14195	T14192	parataxis	0.015,significantly
R4207	T14196	T14195	nsubj	P,0.015
R4208	T14197	T14195	punct	=,0.015
R4209	T14198	T14195	punct	),0.015
R4210	T14199	T14200	punct	(,6
R4211	T14200	T14193	parataxis	6,increased
R4212	T14201	T14200	nummod	152,6
R4213	T14202	T14200	punct	±,6
R4214	T14203	T14200	punct	", ",6
R4215	T14204	T14205	nsubj	n,12
R4216	T14205	T14200	ccomp	12,6
R4217	T14206	T14205	punct	=,12
R4218	T14207	T14200	punct	),6
R4219	T14208	T14209	advmod	when,compared
R4220	T14209	T14182	advcl	compared,was
R4221	T14210	T14209	prep	to,compared
R4222	T14211	T14212	det	the,mice
R4223	T14212	T14210	pobj	mice,to
R4224	T14213	T14212	compound	B6,mice
R4225	T14214	T14182	punct	", ",was
R4226	T14215	T14182	cc	but,was
R4227	T14216	T14217	prep	for,was
R4228	T14217	T14182	conj	was,was
R4229	T14218	T14216	pobj	CSS,for
R4230	T14219	T14218	punct	-,CSS
R4231	T14220	T14218	nummod	5,CSS
R4232	T14221	T14218	cc	and,CSS
R4233	T14222	T14218	conj	CSS,CSS
R4234	T14223	T14222	punct	-,CSS
R4235	T14224	T14222	nummod	5,CSS
R4236	T14225	T14222	punct	×,CSS
R4237	T14226	T14222	nummod	17,CSS
R4238	T14227	T14217	punct	", ",was
R4239	T14228	T14229	det	the,antigen
R4240	T14229	T14217	nsubj	antigen,was
R4241	T14230	T14229	compound	Plg,antigen
R4242	T14231	T14217	acomp	similar,was
R4243	T14232	T14231	prep	to,similar
R4244	T14233	T14232	pobj	values,to
R4245	T14234	T14233	prep	for,values
R4246	T14235	T14236	det	the,mice
R4247	T14236	T14234	pobj	mice,for
R4248	T14237	T14236	compound	B6,mice
R4249	T14238	T14217	punct	.,was
R4250	T14240	T14241	amod	Fibrinolytic,activity
R4251	T14241	T14242	nsubj	activity,was
R4252	T14243	T14242	neg	not,was
R4253	T14244	T14242	acomp	different,was
R4254	T14245	T14244	prep	in,different
R4255	T14246	T14247	det	the,strains
R4256	T14247	T14245	pobj	strains,in
R4257	T14248	T14247	nmod	CSS,strains
R4258	T14249	T14248	punct	-,CSS
R4259	T14250	T14248	nummod	5,CSS
R4260	T14251	T14248	cc	or,CSS
R4261	T14252	T14248	conj	CSS,CSS
R4262	T14253	T14252	punct	-,CSS
R4263	T14254	T14252	nummod	17,CSS
R4264	T14255	T14242	prep	compared,was
R4265	T14256	T14255	prep	to,compared
R4266	T14257	T14258	det	the,mice
R4267	T14258	T14256	pobj	mice,to
R4268	T14259	T14258	compound	B6,mice
R4269	T14260	T14242	punct	.,was
R4270	T14262	T14263	compound	α2,antiplasmin
R4271	T14263	T14265	nsubj	antiplasmin,was
R4272	T14264	T14263	punct	-,antiplasmin
R4273	T14266	T14267	advmod	significantly,reduced
R4274	T14267	T14265	acomp	reduced,was
R4275	T14268	T14269	punct	(,0.01
R4276	T14269	T14266	parataxis	0.01,significantly
R4277	T14270	T14269	nsubj	P,0.01
R4278	T14271	T14269	punct	=,0.01
R4279	T14272	T14269	punct	<,0.01
R4280	T14273	T14269	punct	),0.01
R4281	T14274	T14265	prep	in,was
R4282	T14275	T14276	nmod	CSS,mice
R4283	T14276	T14274	pobj	mice,in
R4284	T14277	T14275	punct	-,CSS
R4285	T14278	T14275	nummod	5,CSS
R4286	T14279	T14280	punct	(,μg
R4287	T14280	T14276	parataxis	μg,mice
R4288	T14281	T14282	quantmod	142,4
R4289	T14282	T14280	nummod	4,μg
R4290	T14283	T14282	punct	±,4
R4291	T14284	T14285	punct	/,mL
R4292	T14285	T14280	prep	mL,μg
R4293	T14286	T14280	punct	", ",μg
R4294	T14287	T14288	nsubj	n,5
R4295	T14288	T14280	ccomp	5,μg
R4296	T14289	T14288	punct	=,5
R4297	T14290	T14280	punct	),μg
R4298	T14291	T14265	punct	", ",was
R4299	T14292	T14293	advmod	significantly,higher
R4300	T14293	T14265	conj	higher,was
R4301	T14294	T14295	punct	(,0.05
R4302	T14295	T14292	parataxis	0.05,significantly
R4303	T14296	T14295	nsubj	P,0.05
R4304	T14297	T14295	punct	<,0.05
R4305	T14298	T14295	punct	),0.05
R4306	T14299	T14293	prep	in,higher
R4307	T14300	T14301	det	the,CSS
R4308	T14301	T14299	pobj	CSS,in
R4309	T14302	T14301	punct	-,CSS
R4310	T14303	T14301	nummod	11,CSS
R4311	T14304	T14305	punct	(,6
R4312	T14305	T14301	parataxis	6,CSS
R4313	T14306	T14305	quantmod	201,6
R4314	T14307	T14305	punct	±,6
R4315	T14308	T14305	punct	", ",6
R4316	T14309	T14310	nsubj	n,8
R4317	T14310	T14305	ccomp	8,6
R4318	T14311	T14310	punct	=,8
R4319	T14312	T14305	punct	),6
R4320	T14313	T14293	punct	", ",higher
R4321	T14314	T14293	cc	but,higher
R4322	T14315	T14316	neg	not,different
R4323	T14316	T14293	conj	different,higher
R4324	T14317	T14316	prep	in,different
R4325	T14318	T14319	nmod	CSS,mice
R4326	T14319	T14317	pobj	mice,in
R4327	T14320	T14318	punct	-,CSS
R4328	T14321	T14318	nummod	17,CSS
R4329	T14322	T14318	cc	or,CSS
R4330	T14323	T14318	conj	CSS,CSS
R4331	T14324	T14323	punct	-,CSS
R4332	T14325	T14323	nummod	5,CSS
R4333	T14326	T14323	punct	×,CSS
R4334	T14327	T14323	nummod	17,CSS
R4335	T14328	T14316	prep	compared,different
R4336	T14329	T14328	prep	to,compared
R4337	T14330	T14331	det	the,mice
R4338	T14331	T14329	pobj	mice,to
R4339	T14332	T14331	compound	B6,mice
R4340	T14333	T14265	punct	.,was
R4341	T14335	T14336	nsubjpass	PAI,determined
R4342	T14337	T14335	punct	-,PAI
R4343	T14338	T14335	nummod	1,PAI
R4344	T14339	T14335	appos	antigen,PAI
R4345	T14340	T14339	cc	and,antigen
R4346	T14341	T14339	conj	activity,antigen
R4347	T14342	T14336	auxpass	were,determined
R4348	T14343	T14336	prep	in,determined
R4349	T14344	T14345	det	the,CSS
R4350	T14345	T14343	pobj	CSS,in
R4351	T14346	T14345	prep	with,CSS
R4352	T14347	T14348	amod	increased,times
R4353	T14348	T14346	pobj	times,with
R4354	T14349	T14348	compound	rebleeding,times
R4355	T14350	T14345	punct	", ",CSS
R4356	T14351	T14345	appos	CSS,CSS
R4357	T14352	T14351	punct	-,CSS
R4358	T14353	T14351	nummod	5,CSS
R4359	T14354	T14351	punct	", ",CSS
R4360	T14355	T14351	conj	CSS,CSS
R4361	T14356	T14355	punct	-,CSS
R4362	T14357	T14355	nummod	11,CSS
R4363	T14358	T14355	punct	", ",CSS
R4364	T14359	T14355	cc	and,CSS
R4365	T14360	T14355	conj	CSS,CSS
R4366	T14361	T14360	punct	-,CSS
R4367	T14362	T14360	nummod	17,CSS
R4368	T14363	T14364	punct	(,Figure
R4369	T14364	T14360	parataxis	Figure,CSS
R4370	T14365	T14364	nummod	6,Figure
R4371	T14366	T14364	punct	),Figure
R4372	T14367	T14345	punct	", ",CSS
R4373	T14368	T14369	det	the,heterosomic
R4374	T14369	T14345	conj	heterosomic,CSS
R4375	T14370	T14369	punct	", ",heterosomic
R4376	T14371	T14372	compound	CSS,5F1
R4377	T14372	T14369	appos	5F1,heterosomic
R4378	T14373	T14372	punct	-,5F1
R4379	T14374	T14372	punct	", ",5F1
R4380	T14375	T14376	compound	CSS,17F1
R4381	T14376	T14372	appos	17F1,5F1
R4382	T14377	T14376	punct	-,17F1
R4383	T14378	T14369	punct	", ",heterosomic
R4384	T14379	T14369	cc	and,heterosomic
R4385	T14380	T14381	amod	double,hetersomic
R4386	T14381	T14369	conj	hetersomic,heterosomic
R4387	T14382	T14381	punct	", ",hetersomic
R4388	T14383	T14381	appos	CSS,hetersomic
R4389	T14384	T14383	punct	-,CSS
R4390	T14385	T14383	nummod	5,CSS
R4391	T14386	T14383	punct	×,CSS
R4392	T14387	T14383	nummod	17,CSS
R4393	T14388	T14336	punct	.,determined
R4394	T14390	T14391	nsubj	CSS,had
R4395	T14392	T14390	punct	-,CSS
R4396	T14393	T14390	nummod	5,CSS
R4397	T14394	T14390	punct	", ",CSS
R4398	T14395	T14390	conj	CSS,CSS
R4399	T14396	T14395	punct	-,CSS
R4400	T14397	T14395	nummod	17,CSS
R4401	T14398	T14395	punct	", ",CSS
R4402	T14399	T14400	compound	CSS,5F1
R4403	T14400	T14395	conj	5F1,CSS
R4404	T14401	T14400	punct	-,5F1
R4405	T14402	T14400	punct	", ",5F1
R4406	T14403	T14400	cc	and,5F1
R4407	T14404	T14405	compound	CSS,17F1
R4408	T14405	T14400	conj	17F1,5F1
R4409	T14406	T14405	punct	-,17F1
R4410	T14407	T14391	advmod	generally,had
R4411	T14408	T14409	amod	reduced,antigen
R4412	T14409	T14391	dobj	antigen,had
R4413	T14410	T14409	nmod	PAI,antigen
R4414	T14411	T14410	punct	-,PAI
R4415	T14412	T14410	nummod	1,PAI
R4416	T14413	T14414	advmod	when,compared
R4417	T14414	T14391	advcl	compared,had
R4418	T14415	T14414	prep	to,compared
R4419	T14416	T14417	compound	B6,mice
R4420	T14417	T14415	pobj	mice,to
R4421	T14418	T14391	punct	.,had
R4422	T14420	T14421	det	The,antigen
R4423	T14421	T14426	nsubj	antigen,was
R4424	T14422	T14421	amod	reduced,antigen
R4425	T14423	T14421	nmod	PAI,antigen
R4426	T14424	T14423	punct	-,PAI
R4427	T14425	T14423	nummod	1,PAI
R4428	T14427	T14428	det	a,trait
R4429	T14428	T14426	attr	trait,was
R4430	T14429	T14428	amod	dominant,trait
R4431	T14430	T14426	prep	due,was
R4432	T14431	T14430	pcomp	to,due
R4433	T14432	T14433	det	the,fact
R4434	T14433	T14430	pobj	fact,due
R4435	T14434	T14435	mark	that,were
R4436	T14435	T14433	acl	were,fact
R4437	T14436	T14437	det	the,values
R4438	T14437	T14435	nsubj	values,were
R4439	T14438	T14435	acomp	similar,were
R4440	T14439	T14438	prep	in,similar
R4441	T14440	T14441	det	the,CSS
R4442	T14441	T14439	pobj	CSS,in
R4443	T14442	T14441	amod	homosomic,CSS
R4444	T14443	T14442	cc	and,homosomic
R4445	T14444	T14442	conj	heterosomic,homosomic
R4446	T14445	T14441	punct	-,CSS
R4447	T14446	T14441	nummod	5,CSS
R4448	T14447	T14441	cc	and,CSS
R4449	T14448	T14441	conj	CSS,CSS
R4450	T14449	T14448	punct	-,CSS
R4451	T14450	T14448	nummod	17,CSS
R4452	T14451	T14426	punct	.,was
R4453	T14453	T14454	det	The,strains
R4454	T14454	T14464	nsubj	strains,had
R4455	T14455	T14454	nmod	CSS,strains
R4456	T14456	T14455	punct	-,CSS
R4457	T14457	T14455	nummod	5,CSS
R4458	T14458	T14455	punct	×,CSS
R4459	T14459	T14455	appos	CSS,CSS
R4460	T14460	T14459	punct	-,CSS
R4461	T14461	T14459	nummod	17,CSS
R4462	T14462	T14463	amod	double,heterosomic
R4463	T14463	T14454	amod	heterosomic,strains
R4464	T14465	T14464	dobj	values,had
R4465	T14466	T14465	amod	similar,values
R4466	T14467	T14466	prep	to,similar
R4467	T14468	T14469	det	the,strains
R4468	T14469	T14467	pobj	strains,to
R4469	T14470	T14469	nmod	B6,strains
R4470	T14471	T14470	cc	and,B6
R4471	T14472	T14473	compound	A,J
R4472	T14473	T14470	conj	J,B6
R4473	T14474	T14473	punct	/,J
R4474	T14475	T14469	compound	parent,strains
R4475	T14476	T14464	punct	.,had
R4476	T14478	T14479	nmod	PAI,activity
R4477	T14479	T14482	nsubjpass	activity,reduced
R4478	T14480	T14478	punct	-,PAI
R4479	T14481	T14478	nummod	1,PAI
R4480	T14483	T14482	auxpass	was,reduced
R4481	T14484	T14482	advmod	significantly,reduced
R4482	T14485	T14482	prep	in,reduced
R4483	T14486	T14487	det	the,mice
R4484	T14487	T14485	pobj	mice,in
R4485	T14488	T14487	nmod	CSS,mice
R4486	T14489	T14488	punct	-,CSS
R4487	T14490	T14488	nummod	5,CSS
R4488	T14491	T14488	cc	and,CSS
R4489	T14492	T14493	compound	CSS,17F1
R4490	T14493	T14488	conj	17F1,CSS
R4491	T14494	T14493	punct	-,17F1
R4492	T14495	T14482	punct	", ",reduced
R4493	T14496	T14482	cc	but,reduced
R4494	T14497	T14498	advmod	again,restored
R4495	T14498	T14482	conj	restored,reduced
R4496	T14499	T14498	prep	in,restored
R4497	T14500	T14501	det	the,strain
R4498	T14501	T14499	pobj	strain,in
R4499	T14502	T14501	nmod	CSS,strain
R4500	T14503	T14502	punct	-,CSS
R4501	T14504	T14502	nummod	5,CSS
R4502	T14505	T14502	punct	×,CSS
R4503	T14506	T14502	appos	CSS,CSS
R4504	T14507	T14506	punct	-,CSS
R4505	T14508	T14506	nummod	17,CSS
R4506	T14509	T14510	det	the,value
R4507	T14510	T14498	nsubjpass	value,restored
R4508	T14511	T14510	prep	for,value
R4509	T14512	T14513	nmod	PAI,activity
R4510	T14513	T14511	pobj	activity,for
R4511	T14514	T14512	punct	-,PAI
R4512	T14515	T14512	nummod	1,PAI
R4513	T14516	T14498	auxpass	was,restored
R4514	T14517	T14498	prep	to,restored
R4515	T14518	T14519	det	the,value
R4516	T14519	T14517	pobj	value,to
R4517	T14520	T14519	prep	of,value
R4518	T14521	T14522	det	the,strains
R4519	T14522	T14520	pobj	strains,of
R4520	T14523	T14522	nmod	B6,strains
R4521	T14524	T14523	cc	and,B6
R4522	T14525	T14526	compound	A,J
R4523	T14526	T14523	conj	J,B6
R4524	T14527	T14526	punct	/,J
R4525	T14528	T14522	compound	parent,strains
R4526	T14529	T14498	punct	.,restored
R4527	T14531	T14532	det	The,antigen
R4528	T14532	T14536	nsubj	antigen,was
R4529	T14533	T14532	nmod	PAI,antigen
R4530	T14534	T14533	punct	-,PAI
R4531	T14535	T14533	nummod	1,PAI
R4532	T14537	T14538	punct	(,ng
R4533	T14538	T14532	parataxis	ng,antigen
R4534	T14539	T14538	nummod	5.4,ng
R4535	T14540	T14541	punct	/,mL
R4536	T14541	T14538	prep	mL,ng
R4537	T14542	T14543	punct	±,0.5
R4538	T14543	T14538	nummod	0.5,ng
R4539	T14544	T14538	punct	", ",ng
R4540	T14545	T14546	nsubj	n,7
R4541	T14546	T14538	ccomp	7,ng
R4542	T14547	T14546	punct	=,7
R4543	T14548	T14538	punct	),ng
R4544	T14549	T14532	cc	and,antigen
R4545	T14550	T14532	conj	activity,antigen
R4546	T14551	T14552	punct	(,U
R4547	T14552	T14550	parataxis	U,activity
R4548	T14553	T14552	nummod	170,U
R4549	T14554	T14555	punct	/,mL
R4550	T14555	T14552	prep	mL,U
R4551	T14556	T14557	punct	±,20
R4552	T14557	T14552	nummod	20,U
R4553	T14558	T14552	punct	", ",U
R4554	T14559	T14560	nsubj	n,6
R4555	T14560	T14552	ccomp	6,U
R4556	T14561	T14560	punct	=,6
R4557	T14562	T14552	punct	),U
R4558	T14563	T14532	prep	in,antigen
R4559	T14564	T14565	det	the,mice
R4560	T14565	T14563	pobj	mice,in
R4561	T14566	T14565	nmod	CSS,mice
R4562	T14567	T14566	punct	-,CSS
R4563	T14568	T14566	nummod	11,CSS
R4564	T14569	T14536	neg	not,was
R4565	T14570	T14536	acomp	different,was
R4566	T14571	T14570	prep	than,different
R4567	T14572	T14571	prep	for,than
R4568	T14573	T14574	compound	B6,mice
R4569	T14574	T14572	pobj	mice,for
R4570	T14575	T14536	punct	.,was
R4571	T14904	T14903	prep	of,Interactions
R4572	T14905	T14904	pobj	CSS,of
R4573	T14906	T14903	prep	for,Interactions
R4574	T14907	T14908	amod	arterial,thrombus
R4575	T14908	T14909	compound	thrombus,formation
R4576	T14909	T14906	pobj	formation,for
R4577	T14911	T14912	det	The,assay
R4578	T14912	T14915	nsubj	assay,was
R4579	T14913	T14914	compound	tail,bleeding
R4580	T14914	T14912	compound	bleeding,assay
R4581	T14916	T14915	acomp	rapid,was
R4582	T14917	T14915	cc	and,was
R4583	T14918	T14915	conj	facilitated,was
R4584	T14919	T14920	det	the,screening
R4585	T14920	T14918	dobj	screening,facilitated
R4586	T14921	T14920	prep	of,screening
R4587	T14922	T14923	det	the,strains
R4588	T14923	T14921	pobj	strains,of
R4589	T14924	T14923	nummod	21,strains
R4590	T14925	T14923	compound	CSS,strains
R4591	T14926	T14915	punct	", ",was
R4592	T14927	T14915	cc	and,was
R4593	T14928	T14929	advmod	subsequently,tested
R4594	T14929	T14915	conj	tested,was
R4595	T14930	T14931	det	the,strains
R4596	T14931	T14929	nsubjpass	strains,tested
R4597	T14932	T14931	amod	identified,strains
R4598	T14933	T14929	auxpass	were,tested
R4599	T14934	T14929	prep	for,tested
R4600	T14935	T14936	amod	arterial,occlusion
R4601	T14936	T14934	pobj	occlusion,for
R4602	T14937	T14929	prep	after,tested
R4603	T14938	T14939	det	the,injury
R4604	T14939	T14937	pobj	injury,after
R4605	T14940	T14939	compound	FeCl3,injury
R4606	T14941	T14942	punct	(,Figure
R4607	T14942	T14929	parataxis	Figure,tested
R4608	T14943	T14942	nummod	7,Figure
R4609	T14944	T14942	punct	),Figure
R4610	T14945	T14929	punct	.,tested
R4611	T14947	T14948	det	The,CSS
R4612	T14948	T14949	nsubj	CSS,had
R4613	T14950	T14948	punct	-,CSS
R4614	T14951	T14948	nummod	5,CSS
R4615	T14952	T14948	cc	and,CSS
R4616	T14953	T14948	conj	CSS,CSS
R4617	T14954	T14953	punct	-,CSS
R4618	T14955	T14953	nummod	17,CSS
R4619	T14956	T14957	compound	occlusion,times
R4620	T14957	T14949	dobj	times,had
R4621	T14958	T14957	amod	similar,times
R4622	T14959	T14958	prep	to,similar
R4623	T14960	T14961	det	the,mice
R4624	T14961	T14959	pobj	mice,to
R4625	T14962	T14961	compound	B6,mice
R4626	T14963	T14949	punct	", ",had
R4627	T14964	T14949	cc	but,had
R4628	T14965	T14966	det	the,progeny
R4629	T14966	T14976	nsubj	progeny,had
R4630	T14967	T14968	advmod	doubly,heterosomic
R4631	T14968	T14966	amod	heterosomic,progeny
R4632	T14969	T14966	nmod	CSS,progeny
R4633	T14970	T14969	punct	-,CSS
R4634	T14971	T14969	nummod	5,CSS
R4635	T14972	T14969	punct	×,CSS
R4636	T14973	T14969	appos	CSS,CSS
R4637	T14974	T14973	punct	-,CSS
R4638	T14975	T14973	nummod	17,CSS
R4639	T14976	T14949	conj	had,had
R4640	T14977	T14978	compound	occlusion,times
R4641	T14978	T14976	dobj	times,had
R4642	T14979	T14978	amod	higher,times
R4643	T14980	T14979	prep	than,higher
R4644	T14981	T14982	preconj	either,mice
R4645	T14982	T14980	pobj	mice,than
R4646	T14983	T14982	det	the,mice
R4647	T14984	T14982	compound	B6,mice
R4648	T14985	T14982	cc	or,mice
R4649	T14986	T14987	det	the,5F1
R4650	T14987	T14982	conj	5F1,mice
R4651	T14988	T14987	amod	heterosomic,5F1
R4652	T14989	T14987	compound	CSS,5F1
R4653	T14990	T14987	punct	-,5F1
R4654	T14991	T14987	cc	and,5F1
R4655	T14992	T14993	compound	CSS,17F1
R4656	T14993	T14987	conj	17F1,5F1
R4657	T14994	T14993	punct	-,17F1
R4658	T14995	T14987	cc	or,5F1
R4659	T14996	T14997	det	the,J
R4660	T14997	T15000	compound	J,strains
R4661	T14998	T14997	compound	A,J
R4662	T14999	T14997	punct	/,J
R4663	T15000	T14987	conj	strains,5F1
R4664	T15001	T14976	punct	.,had
R4665	T15003	T15004	prep	In,occluded
R4666	T15004	T15023	ccomp	occluded,occlude
R4667	T15005	T15006	amod	double,heterosomic
R4668	T15006	T15007	amod	heterosomic,mice
R4669	T15007	T15003	pobj	mice,In
R4670	T15008	T15007	nmod	CSS,mice
R4671	T15009	T15008	punct	-,CSS
R4672	T15010	T15008	nummod	5,CSS
R4673	T15011	T15008	punct	×,CSS
R4674	T15012	T15008	appos	CSS,CSS
R4675	T15013	T15012	punct	-,CSS
R4676	T15014	T15012	nummod	17,CSS
R4677	T15015	T15004	punct	", ",occluded
R4678	T15016	T15017	advmod	only,mice
R4679	T15017	T15004	nsubj	mice,occluded
R4680	T15018	T15017	nummod	one,mice
R4681	T15019	T15018	cc	or,one
R4682	T15020	T15018	conj	three,one
R4683	T15021	T15017	acl	tested,mice
R4684	T15022	T15004	aux	had,occluded
R4685	T15024	T15004	prep	by,occluded
R4686	T15025	T15026	nummod	30,min
R4687	T15026	T15024	pobj	min,by
R4688	T15027	T15023	punct	;,occlude
R4689	T15028	T15029	det	the,mice
R4690	T15029	T15023	nsubj	mice,occlude
R4691	T15030	T15029	amod	other,mice
R4692	T15031	T15029	nummod	two,mice
R4693	T15032	T15023	aux	did,occlude
R4694	T15033	T15023	neg	not,occlude
R4695	T15034	T15023	prep	by,occlude
R4696	T15035	T15036	nummod	30,min
R4697	T15036	T15034	pobj	min,by
R4698	T15037	T15023	punct	.,occlude
R4699	T15039	T15040	mark	While,tested
R4700	T15040	T15050	advcl	tested,suggest
R4701	T15041	T15042	advmod	only,number
R4702	T15042	T15040	nsubjpass	number,tested
R4703	T15043	T15042	det	a,number
R4704	T15044	T15042	amod	small,number
R4705	T15045	T15042	prep	of,number
R4706	T15046	T15047	compound	CSS,mice
R4707	T15047	T15045	pobj	mice,of
R4708	T15048	T15040	aux	have,tested
R4709	T15049	T15040	auxpass	been,tested
R4710	T15051	T15040	prep	for,tested
R4711	T15052	T15053	det	the,occlusion
R4712	T15053	T15051	pobj	occlusion,for
R4713	T15054	T15053	amod	arterial,occlusion
R4714	T15055	T15050	punct	", ",suggest
R4715	T15056	T15057	det	the,results
R4716	T15057	T15050	nsubj	results,suggest
R4717	T15058	T15059	mark	that,determines
R4718	T15059	T15050	ccomp	determines,suggest
R4719	T15060	T15059	nsubj	interaction,determines
R4720	T15061	T15060	prep	of,interaction
R4721	T15062	T15063	det	the,genes
R4722	T15063	T15061	pobj	genes,of
R4723	T15064	T15063	prep	on,genes
R4724	T15065	T15066	nmod	chromosome,5
R4725	T15066	T15064	pobj	5,on
R4726	T15067	T15066	cc	and,5
R4727	T15068	T15066	conj	17,5
R4728	T15069	T15059	advmod	also,determines
R4729	T15070	T15071	amod	arterial,occlusion
R4730	T15071	T15072	compound	occlusion,time
R4731	T15072	T15059	dobj	time,determines
R4732	T15073	T15050	punct	.,suggest
R4737	T18534	T18535	prep	In,assessed
R4738	T18536	T18537	det	this,study
R4739	T18537	T18534	pobj	study,In
R4740	T18538	T18535	punct	", ",assessed
R4741	T18539	T18540	amod	thrombotic,risk
R4742	T18540	T18535	nsubjpass	risk,assessed
R4743	T18541	T18535	auxpass	was,assessed
R4744	T18542	T18535	advmod	systematically,assessed
R4745	T18543	T18535	prep	in,assessed
R4746	T18544	T18545	nummod	two,strains
R4747	T18545	T18543	pobj	strains,in
R4748	T18546	T18545	amod	inbred,strains
R4749	T18547	T18545	prep	of,strains
R4750	T18548	T18547	pobj	mice,of
R4751	T18549	T18550	dep	that,have
R4752	T18550	T18545	relcl	have,strains
R4753	T18551	T18552	amod	marked,differences
R4754	T18552	T18550	dobj	differences,have
R4755	T18553	T18552	prep	in,differences
R4756	T18554	T18553	pobj	susceptibility,in
R4757	T18555	T18554	prep	to,susceptibility
R4758	T18556	T18557	npadvmod	diet,induced
R4759	T18557	T18559	amod	induced,obesity
R4760	T18558	T18557	punct	-,induced
R4761	T18559	T18555	pobj	obesity,to
R4762	T18560	T18559	punct	", ",obesity
R4763	T18561	T18562	npadvmod	diet,induced
R4764	T18562	T18564	amod	induced,atherosclerosis
R4765	T18563	T18562	punct	-,induced
R4766	T18564	T18559	conj	atherosclerosis,obesity
R4767	T18565	T18564	punct	", ",atherosclerosis
R4768	T18566	T18564	cc	and,atherosclerosis
R4769	T18567	T18568	npadvmod	ligation,induced
R4770	T18568	T18570	amod	induced,hyperplasia
R4771	T18569	T18568	punct	-,induced
R4772	T18570	T18564	conj	hyperplasia,atherosclerosis
R4773	T18571	T18570	amod	neointimal,hyperplasia
R4774	T18572	T18570	cc	and,hyperplasia
R4775	T18573	T18574	compound	vessel,remodeling
R4776	T18574	T18570	conj	remodeling,hyperplasia
R4777	T18575	T18535	punct	.,assessed
R4778	T18577	T18578	amod	Arterial,occlusion
R4779	T18578	T18579	compound	occlusion,time
R4780	T18579	T18580	nsubjpass	time,evaluated
R4781	T18581	T18579	punct	", ",time
R4782	T18582	T18583	nmod	tail,bleeding
R4783	T18583	T18584	nmod	bleeding,time
R4784	T18584	T18579	appos	time,time
R4785	T18585	T18583	cc	and,bleeding
R4786	T18586	T18583	conj	rebleeding,bleeding
R4787	T18587	T18580	auxpass	were,evaluated
R4788	T18588	T18580	prep	as,evaluated
R4789	T18589	T18590	amod	potential,predictors
R4790	T18590	T18588	pobj	predictors,as
R4791	T18591	T18590	prep	of,predictors
R4792	T18592	T18593	amod	thrombotic,response
R4793	T18593	T18591	pobj	response,of
R4794	T18594	T18580	punct	.,evaluated
R4795	T18596	T18597	nsubjpass	Assessments,compared
R4796	T18598	T18596	prep	of,Assessments
R4797	T18599	T18600	det	the,strains
R4798	T18600	T18598	pobj	strains,of
R4799	T18601	T18600	nummod	two,strains
R4800	T18602	T18600	amod	inbred,strains
R4801	T18603	T18597	auxpass	were,compared
R4802	T18604	T18597	prep	to,compared
R4803	T18605	T18604	pobj	values,to
R4804	T18606	T18605	prep	from,values
R4805	T18607	T18608	npadvmod	gene,targeted
R4806	T18608	T18609	amod	targeted,mice
R4807	T18609	T18606	pobj	mice,from
R4808	T18610	T18609	prep	of,mice
R4809	T18611	T18612	det	the,network
R4810	T18612	T18610	pobj	network,of
R4811	T18613	T18612	compound	Plg,network
R4812	T18614	T18609	prep	with,mice
R4813	T18615	T18616	amod	altered,responses
R4814	T18616	T18614	pobj	responses,with
R4815	T18617	T18616	amod	fibrinolytic,responses
R4816	T18618	T18606	punct	", ",from
R4817	T18619	T18620	advmod	as,as
R4818	T18620	T18606	cc	as,from
R4819	T18621	T18620	advmod	well,as
R4820	T18622	T18606	conj	in,from
R4821	T18623	T18624	npadvmod	leptin,deficient
R4822	T18624	T18625	amod	deficient,mice
R4823	T18625	T18622	pobj	mice,in
R4824	T18626	T18625	prep	with,mice
R4825	T18627	T18628	det	a,function
R4826	T18628	T18626	pobj	function,with
R4827	T18629	T18628	amod	reduced,function
R4828	T18630	T18628	compound	platelet,function
R4829	T18631	T18597	punct	.,compared
R4830	T18633	T18634	amod	Marked,differences
R4831	T18634	T18635	nsubjpass	differences,found
R4832	T18636	T18635	auxpass	were,found
R4833	T18637	T18635	prep	in,found
R4834	T18638	T18639	det	the,response
R4835	T18639	T18637	pobj	response,in
R4836	T18640	T18639	amod	thrombotic,response
R4837	T18641	T18635	prep	among,found
R4838	T18642	T18643	det	the,strains
R4839	T18643	T18641	pobj	strains,among
R4840	T18644	T18643	nummod	two,strains
R4841	T18645	T18643	amod	inbred,strains
R4842	T18646	T18643	punct	", ",strains
R4843	T18647	T18643	appos	B6,strains
R4844	T18648	T18647	cc	and,B6
R4845	T18649	T18650	compound	A,J
R4846	T18650	T18647	conj	J,B6
R4847	T18651	T18650	punct	/,J
R4848	T18652	T18635	punct	", ",found
R4849	T18653	T18635	cc	and,found
R4850	T18654	T18655	det	the,differences
R4851	T18655	T18657	nsubjpass	differences,correlated
R4852	T18656	T18655	amod	observed,differences
R4853	T18657	T18635	conj	correlated,found
R4854	T18658	T18657	auxpass	were,correlated
R4855	T18659	T18657	neg	not,correlated
R4856	T18660	T18657	prep	with,correlated
R4857	T18661	T18660	pobj	change,with
R4858	T18662	T18661	prep	in,change
R4859	T18663	T18662	pobj	coagulation,in
R4860	T18664	T18663	cc	or,coagulation
R4861	T18665	T18666	compound	platelet,function
R4862	T18666	T18663	conj	function,coagulation
R4863	T18667	T18657	punct	.,correlated
R4864	T18669	T18670	csubj	Screening,identified
R4865	T18671	T18672	det	the,CSS
R4866	T18672	T18669	dobj	CSS,Screening
R4867	T18673	T18674	nummod	three,chromosomes
R4868	T18674	T18670	dobj	chromosomes,identified
R4869	T18675	T18676	dep	that,harbored
R4870	T18676	T18674	relcl	harbored,chromosomes
R4871	T18677	T18676	dobj	genes,harbored
R4872	T18678	T18679	dep	which,contributed
R4873	T18679	T18677	relcl	contributed,genes
R4874	T18680	T18679	prep	to,contributed
R4875	T18681	T18682	det	the,phenotype
R4876	T18682	T18680	pobj	phenotype,to
R4877	T18683	T18684	compound	A,J
R4878	T18684	T18682	compound	J,phenotype
R4879	T18685	T18684	punct	/,J
R4880	T18686	T18682	prep	of,phenotype
R4881	T18687	T18688	amod	increased,time
R4882	T18688	T18686	pobj	time,of
R4883	T18689	T18688	compound	rebleeding,time
R4884	T18690	T18670	punct	.,identified
R4885	T18692	T18693	nsubjpass	Mice,required
R4886	T18694	T18692	amod	homosomic,Mice
R4887	T18695	T18694	prep	for,homosomic
R4888	T18696	T18697	det	these,chromosomes
R4889	T18697	T18695	pobj	chromosomes,for
R4890	T18698	T18694	cc	or,homosomic
R4891	T18699	T18700	advmod	doubly,heterosomic
R4892	T18700	T18694	conj	heterosomic,homosomic
R4893	T18701	T18700	prep	for,heterosomic
R4894	T18702	T18701	pobj	two,for
R4895	T18703	T18702	prep	of,two
R4896	T18704	T18705	det	the,chromosomes
R4897	T18705	T18703	pobj	chromosomes,of
R4898	T18706	T18702	punct	", ",two
R4899	T18707	T18702	appos	5,two
R4900	T18708	T18707	cc	and,5
R4901	T18709	T18707	conj	17,5
R4902	T18710	T18693	punct	", ",required
R4903	T18711	T18693	auxpass	were,required
R4904	T18712	T18713	aux	to,express
R4905	T18713	T18693	advcl	express,required
R4906	T18714	T18715	det	the,phenotype
R4907	T18715	T18713	dobj	phenotype,express
R4908	T18716	T18717	compound	A,J
R4909	T18717	T18715	compound	J,phenotype
R4910	T18718	T18717	punct	/,J
R4911	T18719	T18715	punct	", ",phenotype
R4912	T18720	T18721	amod	elevated,time
R4913	T18721	T18715	appos	time,phenotype
R4914	T18722	T18721	compound	rebleeding,time
R4915	T18723	T18693	punct	.,required
R4916	T18725	T18726	nsubjpass	PAI,decreased
R4917	T18727	T18725	punct	-,PAI
R4918	T18728	T18725	nummod	1,PAI
R4919	T18729	T18725	appos	antigen,PAI
R4920	T18730	T18729	cc	and,antigen
R4921	T18731	T18729	conj	activity,antigen
R4922	T18732	T18726	auxpass	were,decreased
R4923	T18733	T18726	prep	in,decreased
R4924	T18734	T18735	preconj	both,CSS
R4925	T18735	T18733	pobj	CSS,in
R4926	T18736	T18735	punct	-,CSS
R4927	T18737	T18735	nummod	5,CSS
R4928	T18738	T18735	cc	and,CSS
R4929	T18739	T18735	conj	CSS,CSS
R4930	T18740	T18739	punct	-,CSS
R4931	T18741	T18739	nummod	17,CSS
R4932	T18742	T18735	cc	and,CSS
R4933	T18743	T18744	det	the,mice
R4934	T18744	T18735	conj	mice,CSS
R4935	T18745	T18744	amod	heterosomic,mice
R4936	T18746	T18744	punct	", ",mice
R4937	T18747	T18748	compound	CSS,5F1
R4938	T18748	T18744	appos	5F1,mice
R4939	T18749	T18748	punct	-,5F1
R4940	T18750	T18748	cc	and,5F1
R4941	T18751	T18752	compound	CSS,17F1
R4942	T18752	T18748	conj	17F1,5F1
R4943	T18753	T18752	punct	-,17F1
R4944	T18754	T18733	punct	", ",in
R4945	T18755	T18733	cc	but,in
R4946	T18756	T18755	neg	not,but
R4947	T18757	T18733	conj	in,in
R4948	T18758	T18759	det	the,strain
R4949	T18759	T18757	pobj	strain,in
R4950	T18760	T18759	nmod	CSS,strain
R4951	T18761	T18760	punct	-,CSS
R4952	T18762	T18760	nummod	11,CSS
R4953	T18763	T18726	punct	.,decreased
R4954	T18765	T18766	nsubjpass	Values,restored
R4955	T18767	T18766	auxpass	were,restored
R4956	T18768	T18766	prep	in,restored
R4957	T18769	T18770	det	the,heterosomic
R4958	T18770	T18768	pobj	heterosomic,in
R4959	T18771	T18770	advmod	doubly,heterosomic
R4960	T18772	T18766	prep	for,restored
R4961	T18773	T18772	pobj	two,for
R4962	T18774	T18773	prep	of,two
R4963	T18775	T18774	pobj	chromosomes,of
R4964	T18776	T18773	punct	", ",two
R4965	T18777	T18773	appos	5,two
R4966	T18778	T18777	cc	and,5
R4967	T18779	T18777	conj	17,5
R4968	T18780	T18766	punct	.,restored
R4969	T18782	T18783	amod	Arterial,occlusion
R4970	T18783	T18784	compound	occlusion,time
R4971	T18784	T18785	nsubj	time,was
R4972	T18786	T18785	acomp	similar,was
R4973	T18787	T18786	prep	to,similar
R4974	T18788	T18787	pobj	B6,to
R4975	T18789	T18785	prep	in,was
R4976	T18790	T18791	det	the,strains
R4977	T18791	T18789	pobj	strains,in
R4978	T18792	T18791	nmod	CSS,strains
R4979	T18793	T18792	punct	-,CSS
R4980	T18794	T18792	nummod	5,CSS
R4981	T18795	T18792	cc	and,CSS
R4982	T18796	T18792	conj	CSS,CSS
R4983	T18797	T18796	punct	-,CSS
R4984	T18798	T18796	nummod	17,CSS
R4985	T18799	T18791	amod	homozygous,strains
R4986	T18800	T18785	punct	", ",was
R4987	T18801	T18785	cc	but,was
R4988	T18802	T18785	conj	increased,was
R4989	T18803	T18802	prep	in,increased
R4990	T18804	T18805	advmod	doubly,heterosomic
R4991	T18805	T18803	pobj	heterosomic,in
R4992	T18806	T18785	prep	for,was
R4993	T18807	T18806	pobj	two,for
R4994	T18808	T18807	prep	of,two
R4995	T18809	T18808	pobj	chromosomes,of
R4996	T18810	T18807	punct	", ",two
R4997	T18811	T18807	appos	5,two
R4998	T18812	T18811	cc	and,5
R4999	T18813	T18811	conj	17,5
R5000	T18814	T18785	punct	.,was
R5001	T18816	T18817	det	The,model
R5002	T18817	T18821	nsubjpass	model,used
R5003	T18818	T18819	npadvmod	FeCl3,induced
R5004	T18819	T18817	amod	induced,model
R5005	T18820	T18819	punct	-,induced
R5006	T18822	T18817	prep	of,model
R5007	T18823	T18824	amod	vascular,injury
R5008	T18824	T18822	pobj	injury,of
R5009	T18825	T18824	cc	and,injury
R5010	T18826	T18824	conj	thrombosis,injury
R5011	T18827	T18817	prep	in,model
R5012	T18828	T18827	pobj	mice,in
R5013	T18829	T18821	auxpass	is,used
R5014	T18830	T18821	advmod	now,used
R5015	T18831	T18821	advmod	widely,used
R5016	T18832	T18833	aux	to,evaluate
R5017	T18833	T18821	advcl	evaluate,used
R5018	T18834	T18835	amod	genetic,interventions
R5019	T18835	T18833	dobj	interventions,evaluate
R5020	T18836	T18834	cc	and,genetic
R5021	T18837	T18834	conj	pharmacological,genetic
R5022	T18838	T18839	punct	[,24
R5023	T18839	T18821	parataxis	24,used
R5024	T18840	T18839	punct	],24
R5025	T18841	T18821	punct	.,used
R5026	T18843	T18844	det	The,strains
R5027	T18844	T18847	nsubj	strains,had
R5028	T18845	T18844	nummod	two,strains
R5029	T18846	T18844	amod	inbred,strains
R5030	T18848	T18849	amod	marked,differences
R5031	T18849	T18847	dobj	differences,had
R5032	T18850	T18849	prep	in,differences
R5033	T18851	T18852	det	the,time
R5034	T18852	T18850	pobj	time,in
R5035	T18853	T18852	prep	for,time
R5036	T18854	T18853	pobj	occlusion,for
R5037	T18855	T18854	prep	of,occlusion
R5038	T18856	T18857	det	the,artery
R5039	T18857	T18855	pobj	artery,of
R5040	T18858	T18857	amod	carotid,artery
R5041	T18859	T18854	prep	after,occlusion
R5042	T18860	T18861	compound	FeCl3,injury
R5043	T18861	T18859	pobj	injury,after
R5044	T18862	T18847	punct	.,had
R5045	T18864	T18865	prep	After,shortened
R5046	T18866	T18867	compound	FeCl3,treatment
R5047	T18867	T18864	pobj	treatment,After
R5048	T18868	T18865	punct	", ",shortened
R5049	T18869	T18870	compound	thrombus,formation
R5050	T18870	T18865	nsubjpass	formation,shortened
R5051	T18871	T18870	cc	and,formation
R5052	T18872	T18870	conj	occlusion,formation
R5053	T18873	T18865	auxpass	was,shortened
R5054	T18874	T18865	advmod	remarkably,shortened
R5055	T18875	T18865	prep	in,shortened
R5056	T18876	T18877	det	the,mice
R5057	T18877	T18875	pobj	mice,in
R5058	T18878	T18879	compound	A,J
R5059	T18879	T18877	compound	J,mice
R5060	T18880	T18879	punct	/,J
R5061	T18881	T18865	prep	compared,shortened
R5062	T18882	T18881	prep	to,compared
R5063	T18883	T18884	det	the,mice
R5064	T18884	T18882	pobj	mice,to
R5065	T18885	T18884	compound	B6,mice
R5066	T18886	T18865	punct	.,shortened
R5067	T18888	T18889	det	These,results
R5068	T18889	T18890	nsubjpass	results,reported
R5069	T18891	T18890	aux	have,reported
R5070	T18892	T18890	neg	not,reported
R5071	T18893	T18890	advmod	previously,reported
R5072	T18894	T18890	auxpass	been,reported
R5073	T18895	T18890	punct	.,reported
R5074	T18897	T18898	det	A,study
R5075	T18898	T18900	nsubj	study,found
R5076	T18899	T18898	amod	recent,study
R5077	T18901	T18902	punct	[,25
R5078	T18902	T18898	parataxis	25,study
R5079	T18903	T18902	punct	],25
R5080	T18904	T18898	prep	of,study
R5081	T18905	T18906	amod	sheer,stress
R5082	T18906	T18904	pobj	stress,of
R5083	T18907	T18898	prep	in,study
R5084	T18908	T18907	pobj	rats,in
R5085	T18909	T18900	punct	", ",found
R5086	T18910	T18911	mark	that,varied
R5087	T18911	T18900	ccomp	varied,found
R5088	T18912	T18913	det	the,magnitude
R5089	T18913	T18911	nsubj	magnitude,varied
R5090	T18914	T18913	prep	of,magnitude
R5091	T18915	T18914	pobj	changes,of
R5092	T18916	T18915	prep	in,changes
R5093	T18917	T18918	amod	sheer,stress
R5094	T18918	T18916	pobj	stress,in
R5095	T18919	T18913	prep	with,magnitude
R5096	T18920	T18921	amod	increased,flow
R5097	T18921	T18919	pobj	flow,with
R5098	T18922	T18921	compound	blood,flow
R5099	T18923	T18911	prep	with,varied
R5100	T18924	T18925	det	the,strains
R5101	T18925	T18923	pobj	strains,with
R5102	T18926	T18925	amod	different,strains
R5103	T18927	T18900	punct	.,found
R5104	T18929	T18930	amod	Further,investigation
R5105	T18930	T18931	nsubj	investigation,be
R5106	T18932	T18930	punct	", ",investigation
R5107	T18933	T18930	prep	beyond,investigation
R5108	T18934	T18935	det	the,scope
R5109	T18935	T18933	pobj	scope,beyond
R5110	T18936	T18935	prep	of,scope
R5111	T18937	T18938	det	this,study
R5112	T18938	T18936	pobj	study,of
R5113	T18939	T18931	aux	would,be
R5114	T18940	T18931	acomp	necessary,be
R5115	T18941	T18942	aux	to,determine
R5116	T18942	T18931	advcl	determine,be
R5117	T18943	T18944	det	the,contribution
R5118	T18944	T18942	dobj	contribution,determine
R5119	T18945	T18944	prep	in,contribution
R5120	T18946	T18947	det	the,differences
R5121	T18947	T18945	pobj	differences,in
R5122	T18948	T18947	prep	in,differences
R5123	T18949	T18948	pobj	size,in
R5124	T18950	T18947	cc	and,differences
R5125	T18951	T18952	amod	sheer,stress
R5126	T18952	T18947	conj	stress,differences
R5127	T18953	T18952	prep	of,stress
R5128	T18954	T18955	det	the,carotids
R5129	T18955	T18953	pobj	carotids,of
R5130	T18956	T18944	prep	to,contribution
R5131	T18957	T18958	amod	arterial,rates
R5132	T18958	T18956	pobj	rates,to
R5133	T18959	T18958	compound	occlusion,rates
R5134	T18960	T18958	prep	in,rates
R5135	T18961	T18962	det	the,mice
R5136	T18962	T18960	pobj	mice,in
R5137	T18963	T18962	nmod	B6,mice
R5138	T18964	T18963	cc	and,B6
R5139	T18965	T18966	compound	A,J
R5140	T18966	T18963	conj	J,B6
R5141	T18967	T18966	punct	/,J
R5142	T18968	T18931	punct	.,be
R5143	T18970	T18971	prep	In,noted
R5144	T18972	T18973	amod	preliminary,studies
R5145	T18973	T18970	pobj	studies,In
R5146	T18974	T18971	punct	", ",noted
R5147	T18975	T18971	nsubj	we,noted
R5148	T18976	T18971	aux	have,noted
R5149	T18977	T18971	dobj	differences,noted
R5150	T18978	T18977	prep	in,differences
R5151	T18979	T18980	det	the,composition
R5152	T18980	T18978	pobj	composition,in
R5153	T18981	T18980	prep	of,composition
R5154	T18982	T18983	det	the,thrombus
R5155	T18983	T18981	pobj	thrombus,of
R5156	T18984	T18971	prep	in,noted
R5157	T18985	T18986	nmod	B6,mice
R5158	T18986	T18984	pobj	mice,in
R5159	T18987	T18985	cc	and,B6
R5160	T18988	T18989	compound	A,J
R5161	T18989	T18985	conj	J,B6
R5162	T18990	T18989	punct	/,J
R5163	T18991	T18971	punct	.,noted
R5164	T18993	T18994	det	The,pattern
R5165	T18994	T18995	nsubj	pattern,was
R5166	T19075	T19076	det	the,rate
R5167	T18996	T18994	prep	of,pattern
R5168	T19076	T19074	dobj	rate,affect
R5169	T19077	T19076	prep	of,rate
R5170	T18997	T18998	compound	blood,flow
R5171	T19078	T19079	compound	clot,lysis
R5172	T19079	T19077	pobj	lysis,of
R5173	T18998	T18999	compound	flow,cessation
R5174	T19080	T19068	punct	", ",modulate
R5175	T19081	T19068	aux	can,modulate
R5176	T19082	T19083	det	the,events
R5177	T18999	T18996	pobj	cessation,of
R5178	T19083	T19068	dobj	events,modulate
R5179	T19084	T19083	acl	leading,events
R5180	T19085	T19084	prep	to,leading
R5181	T19000	T18994	prep	for,pattern
R5182	T19086	T19087	amod	occlusive,thrombus
R5183	T19087	T19088	compound	thrombus,formation
R5184	T19001	T19002	det	the,strains
R5185	T19088	T19085	pobj	formation,to
R5186	T19089	T19031	punct	.,reduced
R5187	T19002	T19000	pobj	strains,for
R5188	T19091	T19092	det	The,assay
R5189	T19092	T19096	nsubjpass	assay,used
R5190	T19003	T19002	nummod	two,strains
R5191	T19093	T19094	compound	tail,bleeding
R5192	T19094	T19092	compound	bleeding,assay
R5193	T19095	T19094	punct	-,bleeding
R5194	T19004	T19002	amod	inbred,strains
R5195	T19097	T19096	aux	has,used
R5196	T19005	T18995	acomp	different,was
R5197	T19098	T19096	auxpass	been,used
R5198	T19006	T19005	prep	than,different
R5199	T19099	T19096	advmod	extensively,used
R5200	T19100	T19096	prep	in,used
R5201	T19101	T19100	pobj	mice,in
R5202	T19102	T19103	aux	to,assess
R5203	T19007	T19006	prep	for,than
R5204	T19103	T19096	advcl	assess,used
R5205	T19104	T19105	det	the,impact
R5206	T19105	T19103	dobj	impact,assess
R5207	T19008	T19009	det	the,mice
R5208	T19106	T19105	prep	of,impact
R5209	T19009	T19007	pobj	mice,for
R5210	T19107	T19106	pobj	deficiencies,of
R5211	T19108	T19107	cc	and,deficiencies
R5212	T19109	T19110	advmod	over,expression
R5213	T19010	T19009	compound	Lepob,mice
R5214	T19110	T19107	conj	expression,deficiencies
R5215	T19111	T19107	prep	of,deficiencies
R5216	T19112	T19113	nmod	platelet,proteins
R5217	T19011	T19012	punct	[,26
R5218	T19113	T19111	pobj	proteins,of
R5219	T19114	T19112	cc	and,platelet
R5220	T19012	T19009	parataxis	26,mice
R5221	T19115	T19112	conj	coagulation,platelet
R5222	T19116	T19107	prep	in,deficiencies
R5223	T19117	T19116	pobj	mice,in
R5224	T19013	T19012	punct	],26
R5225	T19118	T19096	punct	.,used
R5226	T19120	T19121	nsubj	Sweeny,screened
R5227	T19014	T19009	prep	with,mice
R5228	T19122	T19123	advmod	et,al
R5229	T19123	T19120	advmod	al,Sweeny
R5230	T19015	T19016	amod	impaired,function
R5231	T19124	T19125	punct	[,28
R5232	T19125	T19120	parataxis	28,Sweeny
R5233	T19126	T19125	punct	],28
R5234	T19016	T19014	pobj	function,with
R5235	T19127	T19128	nummod	25,strains
R5236	T19128	T19121	dobj	strains,screened
R5237	T19017	T19016	compound	platelet,function
R5238	T19129	T19128	prep	of,strains
R5239	T19130	T19129	pobj	mice,of
R5240	T19131	T19121	cc	and,screened
R5241	T19018	T18995	punct	", ",was
R5242	T19132	T19121	conj	found,screened
R5243	T19133	T19134	advmod	only,mice
R5244	T19019	T18995	cc	and,was
R5245	T19134	T19139	nsubj	mice,have
R5246	T19135	T19134	det	the,mice
R5247	T19136	T19137	compound	RIIS,J
R5248	T19020	T19021	compound	coagulation,time
R5249	T19137	T19134	compound	J,mice
R5250	T19138	T19137	punct	/,J
R5251	T19139	T19132	ccomp	have,found
R5252	T19140	T19139	aux	to,have
R5253	T19141	T19142	amod	increased,time
R5254	T19142	T19139	dobj	time,have
R5255	T19021	T19022	nsubj	time,was
R5256	T19143	T19142	compound	bleeding,time
R5257	T19144	T19142	prep	due,time
R5258	T19145	T19144	pcomp	to,due
R5259	T19022	T18995	conj	was,was
R5260	T19146	T19147	amod	reduced,antigen
R5261	T19147	T19144	pobj	antigen,due
R5262	T19023	T19022	acomp	similar,was
R5263	T19148	T19149	compound	von,Willebrand
R5264	T19149	T19147	compound	Willebrand,antigen
R5265	T19150	T19121	punct	.,screened
R5266	T19024	T19022	prep	in,was
R5267	T19152	T19153	nsubj	Broze,evaluated
R5268	T19025	T19026	det	the,strains
R5269	T19154	T19155	advmod	et,al
R5270	T19155	T19152	advmod	al,Broze
R5271	T19026	T19024	pobj	strains,in
R5272	T19156	T19157	punct	[,29
R5273	T19157	T19152	parataxis	29,Broze
R5274	T19027	T19026	nummod	two,strains
R5275	T19158	T19157	punct	],29
R5276	T19159	T19153	dobj	mice,evaluated
R5277	T19160	T19159	prep	with,mice
R5278	T19028	T19022	punct	.,was
R5279	T19161	T19162	compound	gene,deletions
R5280	T19162	T19160	pobj	deletions,with
R5281	T19163	T19162	prep	of,deletions
R5282	T19030	T19031	prep	In,reduced
R5283	T19164	T19165	det	the,pathway
R5284	T19165	T19163	pobj	pathway,of
R5285	T19166	T19165	compound	coagulation,pathway
R5286	T19167	T19153	cc	and,evaluated
R5287	T19032	T19033	det	the,mice
R5288	T19168	T19153	conj	found,evaluated
R5289	T19169	T19170	mark	that,persisted
R5290	T19170	T19168	ccomp	persisted,found
R5291	T19171	T19172	mark	while,increased
R5292	T19033	T19030	pobj	mice,In
R5293	T19172	T19170	advcl	increased,persisted
R5294	T19173	T19174	compound	bleeding,time
R5295	T19034	T19033	prep	with,mice
R5296	T19174	T19172	nsubjpass	time,increased
R5297	T19175	T19172	auxpass	was,increased
R5298	T19176	T19172	neg	not,increased
R5299	T19035	T19034	pobj	deficiencies,with
R5300	T19177	T19170	punct	", ",persisted
R5301	T19178	T19170	nsubj	rebleeding,persisted
R5302	T19036	T19035	prep	of,deficiencies
R5303	T19179	T19170	prep	despite,persisted
R5304	T19180	T19179	pobj	electrocautery,despite
R5305	T19037	T19038	det	the,network
R5306	T19038	T19036	pobj	network,of
R5307	T19039	T19038	compound	Plg,network
R5308	T19181	T19180	prep	of,electrocautery
R5309	T19182	T19183	det	the,tail
R5310	T19040	T19041	punct	[,27
R5311	T19041	T19033	parataxis	27,mice
R5312	T19183	T19181	pobj	tail,of
R5313	T19042	T19041	punct	],27
R5314	T19184	T19170	prep	in,persisted
R5315	T19185	T19186	npadvmod	FVIII,deficient
R5316	T19186	T19189	amod	deficient,mice
R5317	T19043	T19031	punct	", ",reduced
R5318	T19187	T19185	cc	and,FVIII
R5319	T19188	T19185	conj	FIX,FVIII
R5320	T19189	T19184	pobj	mice,in
R5321	T19044	T19045	compound	thrombus,formation
R5322	T19190	T19153	punct	.,evaluated
R5323	T19045	T19046	compound	formation,time
R5324	T19192	T19193	det	This,observation
R5325	T19193	T19194	nsubj	observation,raised
R5326	T19046	T19031	nsubj	time,reduced
R5327	T19195	T19196	det	the,possibility
R5328	T19047	T19031	aux	was,reduced
R5329	T19196	T19194	dobj	possibility,raised
R5330	T19197	T19198	mark	that,be
R5331	T19198	T19196	acl	be,possibility
R5332	T19048	T19031	prep	in,reduced
R5333	T19199	T19200	compound	rebleeding,time
R5334	T19200	T19198	nsubj	time,be
R5335	T19201	T19198	aux	may,be
R5336	T19049	T19050	det	the,mice
R5337	T19202	T19203	det	a,reporter
R5338	T19203	T19198	attr	reporter,be
R5339	T19204	T19203	amod	sensitive,reporter
R5340	T19050	T19048	pobj	mice,in
R5341	T19205	T19203	prep	of,reporter
R5342	T19206	T19207	amod	genetic,influences
R5343	T19207	T19205	pobj	influences,of
R5344	T19051	T19050	nmod	Plg,mice
R5345	T19208	T19207	prep	on,influences
R5346	T19209	T19210	compound	thrombus,formation
R5347	T19210	T19208	pobj	formation,on
R5348	T19052	T19051	punct	-,Plg
R5349	T19211	T19210	cc	and,formation
R5350	T19212	T19210	conj	stability,formation
R5351	T19213	T19194	punct	.,raised
R5352	T19053	T19051	punct	/,Plg
R5353	T19215	T19216	nsubj	Mice,increased
R5354	T19054	T19051	punct	-,Plg
R5355	T19217	T19218	dep	that,are
R5356	T19218	T19215	relcl	are,Mice
R5357	T19219	T19218	acomp	deficient,are
R5358	T19220	T19219	prep	in,deficient
R5359	T19221	T19220	pobj	factors,in
R5360	T19222	T19221	acl	required,factors
R5361	T19055	T19031	punct	", ",reduced
R5362	T19223	T19222	prep	for,required
R5363	T19224	T19225	amod	normal,function
R5364	T19225	T19223	pobj	function,for
R5365	T19056	T19031	cc	but,reduced
R5366	T19226	T19225	compound	platelet,function
R5367	T19227	T19225	punct	", ",function
R5368	T19228	T19229	compound	platelet,Ib
R5369	T19057	T19031	conj	increased,reduced
R5370	T19229	T19225	conj	Ib,function
R5371	T19230	T19229	compound	glycoprotein,Ib
R5372	T19231	T19232	punct	[,30
R5373	T19058	T19057	prep	in,increased
R5374	T19232	T19229	parataxis	30,Ib
R5375	T19059	T19060	det	the,mice
R5376	T19233	T19232	punct	],30
R5377	T19234	T19229	punct	", ",Ib
R5378	T19235	T19229	cc	and,Ib
R5379	T19236	T19237	npadvmod	protease,activated
R5380	T19060	T19058	pobj	mice,in
R5381	T19237	T19239	amod	activated,receptor
R5382	T19238	T19237	punct	-,activated
R5383	T19061	T19060	nmod	PAI,mice
R5384	T19239	T19229	conj	receptor,Ib
R5385	T19240	T19239	punct	-,receptor
R5386	T19241	T19239	nummod	4,receptor
R5387	T19062	T19061	punct	-,PAI
R5388	T19242	T19222	punct	", ",required
R5389	T19243	T19244	punct	[,31
R5390	T19244	T19222	parataxis	31,required
R5391	T19063	T19061	punct	/,PAI
R5392	T19245	T19244	punct	],31
R5393	T19246	T19216	aux	have,increased
R5394	T19247	T19248	compound	tail,bleeding
R5395	T19064	T19061	punct	-,PAI
R5396	T19248	T19249	compound	bleeding,time
R5397	T19249	T19216	dobj	time,increased
R5398	T19250	T19216	punct	.,increased
R5399	T19065	T19031	punct	", ",reduced
R5400	T19252	T19253	det	The,deficiency
R5401	T19253	T19255	nsubj	deficiency,shows
R5402	T19066	T19031	advcl	suggesting,reduced
R5403	T19254	T19253	compound	leptin,deficiency
R5404	T19256	T19253	prep	with,deficiency
R5405	T19067	T19068	mark	that,modulate
R5406	T19257	T19258	amod	reduced,aggregation
R5407	T19258	T19256	pobj	aggregation,with
R5408	T19259	T19258	compound	platelet,aggregation
R5409	T19260	T19255	advmod	clearly,shows
R5410	T19261	T19262	det	a,increase
R5411	T19262	T19255	dobj	increase,shows
R5412	T19068	T19066	ccomp	modulate,suggesting
R5413	T19263	T19262	amod	marked,increase
R5414	T19264	T19262	prep	in,increase
R5415	T19265	T19266	compound	bleeding,time
R5416	T19266	T19264	pobj	time,in
R5417	T19069	T19068	nsubj	alterations,modulate
R5418	T19267	T19255	cc	and,shows
R5419	T19268	T19269	det	the,time
R5420	T19070	T19069	prep	in,alterations
R5421	T19071	T19072	compound	plasmin,activity
R5422	T19269	T19272	nsubj	time,suggests
R5423	T19270	T19269	amod	increased,time
R5424	T19072	T19070	pobj	activity,in
R5425	T19271	T19269	compound	bleeding,time
R5426	T19272	T19255	conj	suggests,shows
R5427	T19073	T19074	dep	that,affect
R5428	T19273	T19269	prep	in,time
R5429	T19074	T19069	relcl	affect,alterations
R5430	T19274	T19275	nmod	Plg,mice
R5431	T19275	T19273	pobj	mice,in
R5432	T19276	T19274	punct	-,Plg
R5433	T19277	T19274	punct	/,Plg
R5434	T19287	T19286	cc	and,Plg
R5435	T19278	T19274	punct	-,Plg
R5436	T19279	T19274	cc	and,Plg
R5437	T19280	T19274	conj	uPA,Plg
R5438	T19288	T19286	conj	uPA,Plg
R5439	T19281	T19280	punct	-,uPA
R5440	T19282	T19280	punct	/,uPA
R5441	T19283	T19280	punct	-,uPA
R5442	T19289	T19285	aux	may,exert
R5443	T19284	T19285	mark	that,exert
R5444	T19285	T19272	ccomp	exert,suggests
R5445	T19286	T19285	nsubj	Plg,exert
R5446	T19290	T19291	det	an,influence
R5447	T19291	T19285	dobj	influence,exert
R5448	T19292	T19291	prep	on,influence
R5449	T19293	T19294	compound	platelet,response
R5450	T19393	T19377	conj	had,had
R5451	T19294	T19292	pobj	response,on
R5452	T19394	T19395	det	an,time
R5453	T19395	T19393	dobj	time,had
R5454	T19295	T19296	aux	to,promote
R5455	T19396	T19395	amod	increased,time
R5456	T19397	T19395	compound	bleeding,time
R5457	T19398	T19395	amod	similar,time
R5458	T19296	T19285	advcl	promote,exert
R5459	T19399	T19398	prep	to,similar
R5460	T19400	T19401	det	the,mice
R5461	T19401	T19399	pobj	mice,to
R5462	T19297	T19298	amod	normal,formation
R5463	T19402	T19401	nmod	Plg,mice
R5464	T19403	T19402	punct	-,Plg
R5465	T19404	T19402	punct	/,Plg
R5466	T19298	T19296	dobj	formation,promote
R5467	T19405	T19402	punct	-,Plg
R5468	T19406	T19407	punct	(,J.
R5469	T19407	T19393	meta	J.,had
R5470	T19299	T19298	compound	thrombus,formation
R5471	T19408	T19407	nmod	Hoover,J.
R5472	T19409	T19407	punct	-,J.
R5473	T19410	T19407	nmod	Plow,J.
R5474	T19300	T19272	punct	.,suggests
R5475	T19411	T19407	punct	", ",J.
R5476	T19412	T19407	conj	A.,J.
R5477	T19413	T19412	nmod	Shchurin,A.
R5478	T19302	T19303	advmod	Overall,suggests
R5479	T19414	T19412	punct	", ",A.
R5480	T19415	T19412	cc	and,A.
R5481	T19416	T19412	conj	E.,A.
R5482	T19417	T19416	nmod	Hart,E.
R5483	T19304	T19303	punct	", ",suggests
R5484	T19418	T19416	punct	", ",E.
R5485	T19419	T19420	amod	unpublished,results
R5486	T19305	T19306	det	the,increase
R5487	T19420	T19416	conj	results,E.
R5488	T19421	T19420	punct	),results
R5489	T19422	T19393	punct	.,had
R5490	T19306	T19303	nsubj	increase,suggests
R5491	T19424	T19425	amod	Increased,times
R5492	T19425	T19429	nsubjpass	times,reported
R5493	T19307	T19306	amod	marked,increase
R5494	T19426	T19425	nmod	bleeding,times
R5495	T19427	T19426	cc	or,bleeding
R5496	T19428	T19426	conj	rebleeding,bleeding
R5497	T19308	T19306	prep	in,increase
R5498	T19430	T19429	aux	have,reported
R5499	T19431	T19429	neg	not,reported
R5500	T19432	T19429	auxpass	been,reported
R5501	T19309	T19310	compound	rebleeding,times
R5502	T19433	T19429	prep	in,reported
R5503	T19434	T19433	pobj	any,in
R5504	T19310	T19308	pobj	times,in
R5505	T19435	T19434	prep	of,any
R5506	T19436	T19437	det	the,mice
R5507	T19311	T19306	acl	observed,increase
R5508	T19437	T19435	pobj	mice,of
R5509	T19312	T19311	prep	in,observed
R5510	T19438	T19439	compound	Plg,network
R5511	T19439	T19440	npadvmod	network,targeted
R5512	T19440	T19437	amod	targeted,mice
R5513	T19441	T19429	punct	.,reported
R5514	T19443	T19444	nsubj	Matsuno,reported
R5515	T19313	T19314	amod	certain,strains
R5516	T19445	T19446	advmod	et,al
R5517	T19446	T19443	advmod	al,Matsuno
R5518	T19314	T19312	pobj	strains,in
R5519	T19447	T19448	punct	[,32
R5520	T19448	T19443	parataxis	32,Matsuno
R5521	T19315	T19314	compound	mouse,strains
R5522	T19449	T19448	punct	],32
R5523	T19450	T19451	det	no,difference
R5524	T19451	T19444	dobj	difference,reported
R5525	T19316	T19317	amod	genetic,factors
R5526	T19452	T19451	prep	in,difference
R5527	T19453	T19454	compound	bleeding,time
R5528	T19317	T19318	nsubj	factors,play
R5529	T19318	T19303	advcl	play,suggests
R5530	T19454	T19452	pobj	time,in
R5531	T19319	T19317	amod	other,factors
R5532	T19455	T19451	prep	for,difference
R5533	T19456	T19457	nmod	tPA,mice
R5534	T19457	T19455	pobj	mice,for
R5535	T19320	T19319	prep	than,other
R5536	T19458	T19456	punct	-,tPA
R5537	T19459	T19456	punct	/,tPA
R5538	T19321	T19320	pobj	coagulation,than
R5539	T19460	T19456	punct	-,tPA
R5540	T19461	T19456	punct	", ",tPA
R5541	T19462	T19456	appos	uPA,tPA
R5542	T19322	T19318	aux	may,play
R5543	T19463	T19462	punct	-,uPA
R5544	T19464	T19462	punct	/,uPA
R5545	T19465	T19462	punct	-,uPA
R5546	T19323	T19324	det	a,role
R5547	T19466	T19456	punct	", ",tPA
R5548	T19467	T19456	appos	PAI,tPA
R5549	T19468	T19467	punct	-,PAI
R5550	T19324	T19318	dobj	role,play
R5551	T19469	T19467	nummod	1,PAI
R5552	T19470	T19467	punct	-,PAI
R5553	T19471	T19467	punct	/,PAI
R5554	T19325	T19318	prep	in,play
R5555	T19472	T19467	punct	-,PAI
R5556	T19473	T19457	prep	compared,mice
R5557	T19474	T19473	prep	to,compared
R5558	T19326	T19327	det	the,stability
R5559	T19475	T19476	compound	WT,mice
R5560	T19476	T19474	pobj	mice,to
R5561	T19477	T19444	punct	", ",reported
R5562	T19327	T19325	pobj	stability,in
R5563	T19478	T19444	cc	and,reported
R5564	T19479	T19480	det	the,assay
R5565	T19480	T19481	nsubj	assay,was
R5566	T19481	T19444	conj	was,reported
R5567	T19482	T19481	acomp	similar,was
R5568	T19483	T19444	punct	", ",reported
R5569	T19328	T19327	prep	of,stability
R5570	T19484	T19444	cc	but,reported
R5571	T19485	T19486	det	the,segment
R5572	T19486	T19489	nsubj	segment,was
R5573	T19487	T19488	compound	tail,clip
R5574	T19329	T19330	det	a,thrombus
R5575	T19488	T19486	compound	clip,segment
R5576	T19489	T19444	conj	was,reported
R5577	T19490	T19491	advmod	considerably,shorter
R5578	T19330	T19328	pobj	thrombus,of
R5579	T19491	T19489	acomp	shorter,was
R5580	T19492	T19489	cc	and,was
R5581	T19331	T19303	punct	.,suggests
R5582	T19493	T19494	compound	bleeding,times
R5583	T19494	T19495	nsubj	times,reduced
R5584	T19495	T19489	conj	reduced,was
R5585	T19496	T19495	prep	compared,reduced
R5586	T19333	T19334	prep	In,have
R5587	T19497	T19496	prep	to,compared
R5588	T19498	T19499	det	the,times
R5589	T19335	T19336	det	the,assay
R5590	T19336	T19333	pobj	assay,In
R5591	T19499	T19497	pobj	times,to
R5592	T19337	T19338	compound	tail,bleeding
R5593	T19500	T19499	acl	reported,times
R5594	T19501	T19500	prep	in,reported
R5595	T19338	T19336	compound	bleeding,assay
R5596	T19502	T19503	poss	our,study
R5597	T19503	T19501	pobj	study,in
R5598	T19504	T19489	punct	.,was
R5599	T19339	T19334	punct	", ",have
R5600	T19506	T19507	compound	Bleeding,time
R5601	T19340	T19341	compound	A,J
R5602	T19507	T19508	nsubjpass	time,reported
R5603	T19509	T19508	aux	has,reported
R5604	T19341	T19343	compound	J,mice
R5605	T19510	T19508	neg	not,reported
R5606	T19511	T19508	auxpass	been,reported
R5607	T19342	T19341	punct	/,J
R5608	T19512	T19508	advmod	previously,reported
R5609	T19513	T19508	prep	for,reported
R5610	T19514	T19515	nmod	Plg,mice
R5611	T19343	T19334	nsubj	mice,have
R5612	T19515	T19513	pobj	mice,for
R5613	T19516	T19514	punct	-,Plg
R5614	T19517	T19514	punct	/,Plg
R5615	T19518	T19514	punct	-,Plg
R5616	T19519	T19508	punct	.,reported
R5617	T19344	T19334	aux	did,have
R5618	T19521	T19522	nsubj	We,found
R5619	T19523	T19522	aux	have,found
R5620	T19345	T19334	neg	not,have
R5621	T19346	T19334	dobj	changes,have
R5622	T19524	T19525	amod	similar,values
R5623	T19525	T19522	dobj	values,found
R5624	T19347	T19346	prep	in,changes
R5625	T19526	T19525	prep	for,values
R5626	T19527	T19528	nmod	Plg,mice
R5627	T19348	T19349	compound	bleeding,time
R5628	T19528	T19526	pobj	mice,for
R5629	T19529	T19527	punct	-,Plg
R5630	T19530	T19527	punct	/,Plg
R5631	T19349	T19347	pobj	time,in
R5632	T19531	T19527	punct	-,Plg
R5633	T19532	T19528	prep	in,mice
R5634	T19350	T19334	punct	", ",have
R5635	T19533	T19534	det	a,background
R5636	T19534	T19532	pobj	background,in
R5637	T19535	T19536	nummod	50,%
R5638	T19351	T19334	cc	but,have
R5639	T19536	T19537	nmod	%,B6
R5640	T19537	T19534	nmod	B6,background
R5641	T19538	T19537	punct	:,B6
R5642	T19352	T19353	compound	rebleeding,time
R5643	T19539	T19540	nummod	50,%
R5644	T19540	T19537	appos	%,B6
R5645	T19353	T19354	nsubj	time,was
R5646	T19541	T19540	nummod	129,%
R5647	T19542	T19543	punct	(,J.
R5648	T19543	T19522	meta	J.,found
R5649	T19544	T19543	nmod	Hoover,J.
R5650	T19354	T19334	conj	was,have
R5651	T19545	T19543	punct	-,J.
R5652	T19546	T19543	nmod	Plow,J.
R5653	T19547	T19543	punct	", ",J.
R5654	T19548	T19543	conj	A.,J.
R5655	T19549	T19548	nmod	Shchurin,A.
R5656	T19355	T19354	acomp	higher,was
R5657	T19550	T19548	punct	", ",A.
R5658	T19551	T19548	cc	and,A.
R5659	T19356	T19354	prep	compared,was
R5660	T19552	T19548	conj	E.,A.
R5661	T19553	T19552	nmod	Hart,E.
R5662	T19554	T19552	punct	", ",E.
R5663	T19555	T19556	amod	unpublished,results
R5664	T19357	T19356	prep	to,compared
R5665	T19556	T19552	conj	results,E.
R5666	T19557	T19556	punct	),results
R5667	T19558	T19522	punct	.,found
R5668	T19560	T19561	det	The,results
R5669	T19561	T19562	nsubj	results,suggest
R5670	T19358	T19359	compound	B6,mice
R5671	T19563	T19561	prep	of,results
R5672	T19564	T19565	det	this,study
R5673	T19359	T19357	pobj	mice,to
R5674	T19565	T19563	pobj	study,of
R5675	T19566	T19567	mark	that,determined
R5676	T19567	T19562	advcl	determined,suggest
R5677	T19360	T19354	punct	.,was
R5678	T19568	T19567	preconj	not,determined
R5679	T19569	T19568	advmod	only,not
R5680	T19570	T19567	auxpass	is,determined
R5681	T19362	T19363	prep	In,had
R5682	T19571	T19572	compound	bleeding,time
R5683	T19572	T19567	nsubjpass	time,determined
R5684	T19573	T19567	advmod	genetically,determined
R5685	T19574	T19567	agent	by,determined
R5686	T19364	T19365	poss	our,study
R5687	T19575	T19574	pobj	background,by
R5688	T19576	T19567	punct	", ",determined
R5689	T19577	T19567	cc	but,determined
R5690	T19578	T19577	advmod	also,but
R5691	T19365	T19362	pobj	study,In
R5692	T19579	T19580	mark	that,determined
R5693	T19580	T19567	conj	determined,determined
R5694	T19366	T19363	punct	", ",had
R5695	T19581	T19582	compound	tail,rebleeding
R5696	T19582	T19583	compound	rebleeding,time
R5697	T19583	T19580	nsubjpass	time,determined
R5698	T19367	T19368	nmod	Plg,mice
R5699	T19584	T19580	auxpass	is,determined
R5700	T19585	T19580	advmod	genetically,determined
R5701	T19586	T19562	punct	.,suggest
R5702	T19368	T19363	nsubj	mice,had
R5703	T19588	T19589	mark	While,be
R5704	T19369	T19367	punct	-,Plg
R5705	T19589	T19594	advcl	be,suggest
R5706	T19590	T19591	compound	blood,pressure
R5707	T19591	T19589	nsubj	pressure,be
R5708	T19370	T19367	punct	/,Plg
R5709	T19592	T19589	aux	could,be
R5710	T19593	T19589	advmod	conceivably,be
R5711	T19371	T19367	punct	-,Plg
R5712	T19595	T19589	acomp	higher,be
R5713	T19596	T19589	prep	in,be
R5714	T19597	T19596	pobj	mice,in
R5715	T19372	T19373	amod	increased,time
R5716	T19598	T19597	prep	with,mice
R5717	T19599	T19600	amod	elevated,time
R5718	T19600	T19598	pobj	time,with
R5719	T19601	T19602	compound	tail,bleeding
R5720	T19602	T19600	compound	bleeding,time
R5721	T19603	T19594	punct	", ",suggest
R5722	T19373	T19363	dobj	time,had
R5723	T19604	T19605	amod	several,studies
R5724	T19374	T19373	compound	bleeding,time
R5725	T19375	T19363	punct	", ",had
R5726	T19376	T19377	nsubj	PAI,had
R5727	T19605	T19594	nsubj	studies,suggest
R5728	T19377	T19363	conj	had,had
R5729	T19606	T19607	mark	that,is
R5730	T19378	T19376	punct	-,PAI
R5731	T19379	T19376	nummod	1,PAI
R5732	T19607	T19594	ccomp	is,suggest
R5733	T19608	T19607	nsubj	this,is
R5734	T19380	T19376	punct	-,PAI
R5735	T19609	T19607	neg	not,is
R5736	T19610	T19611	det	the,case
R5737	T19611	T19607	attr	case,is
R5738	T19381	T19376	punct	/,PAI
R5739	T19612	T19594	punct	.,suggest
R5740	T19382	T19376	punct	-,PAI
R5741	T19614	T19615	nsubj	Studies,reported
R5742	T19383	T19384	amod	decreased,time
R5743	T19616	T19614	prep	of,Studies
R5744	T19617	T19618	nmod	A,J
R5745	T19384	T19377	dobj	time,had
R5746	T19618	T19620	nmod	J,mice
R5747	T19619	T19618	punct	/,J
R5748	T19385	T19384	compound	rebleeding,time
R5749	T19620	T19616	pobj	mice,of
R5750	T19621	T19622	punct	[,33
R5751	T19622	T19618	parataxis	33,J
R5752	T19386	T19377	punct	", ",had
R5753	T19623	T19624	punct	-,36
R5754	T19624	T19622	prep	36,33
R5755	T19387	T19377	cc	and,had
R5756	T19625	T19622	punct	],33
R5757	T19626	T19615	aux	have,reported
R5758	T19627	T19628	preconj	either,pressure
R5759	T19388	T19389	nmod	uPA,mice
R5760	T19628	T19615	dobj	pressure,reported
R5761	T19629	T19628	amod	decreased,pressure
R5762	T19389	T19393	nsubj	mice,had
R5763	T19630	T19628	compound	blood,pressure
R5764	T19631	T19628	cc	or,pressure
R5765	T19632	T19633	det	no,difference
R5766	T19390	T19388	punct	-,uPA
R5767	T19633	T19628	conj	difference,pressure
R5768	T19634	T19628	prep	compared,pressure
R5769	T19635	T19634	prep	to,compared
R5770	T19636	T19637	det	the,mice
R5771	T19637	T19635	pobj	mice,to
R5772	T19638	T19637	compound	B6,mice
R5773	T19391	T19388	punct	/,uPA
R5774	T19639	T19615	punct	.,reported
R5775	T19392	T19388	punct	-,uPA
R5776	T19641	T19642	compound	Blood,pressure
R5777	T19642	T19643	nsubjpass	pressure,measured
R5778	T19711	T19709	pobj	pressure,between
R5779	T19644	T19643	auxpass	was,measured
R5780	T19645	T19643	prep	in,measured
R5781	T19646	T19647	det	the,mice
R5782	T19647	T19645	pobj	mice,in
R5783	T19648	T19647	nmod	Plg,mice
R5784	T19712	T19711	cc	and,pressure
R5785	T19649	T19648	punct	-,Plg
R5786	T19650	T19648	punct	/,Plg
R5787	T19651	T19648	punct	-,Plg
R5788	T19713	T19714	nmod	tail,times
R5789	T19652	T19653	punct	(,D.
R5790	T19653	T19643	meta	D.,measured
R5791	T19654	T19653	nmod	Hellard,D.
R5792	T19714	T19711	conj	times,pressure
R5793	T19655	T19653	punct	", ",D.
R5794	T19656	T19653	conj	J.,D.
R5795	T19657	T19656	nmod	Hoover,J.
R5796	T19715	T19714	nmod	bleeding,times
R5797	T19658	T19656	punct	-,J.
R5798	T19659	T19656	nmod	Plow,J.
R5799	T19716	T19715	cc	or,bleeding
R5800	T19660	T19656	punct	", ",J.
R5801	T19661	T19656	cc	and,J.
R5802	T19662	T19656	conj	E.,J.
R5803	T19717	T19715	conj	rebleeding,bleeding
R5804	T19663	T19662	nmod	Plow,E.
R5805	T19664	T19662	punct	", ",E.
R5806	T19665	T19666	amod	unpublished,results
R5807	T19718	T19706	punct	.,is
R5808	T19666	T19662	conj	results,E.
R5809	T19667	T19666	punct	),results
R5810	T19668	T19643	punct	", ",measured
R5811	T19720	T19721	amod	Morphometric,analysis
R5812	T19669	T19643	cc	and,measured
R5813	T19670	T19671	det	these,mice
R5814	T19671	T19672	nsubj	mice,have
R5815	T19672	T19643	conj	have,measured
R5816	T19721	T19722	nsubj	analysis,indicated
R5817	T19673	T19674	amod	reduced,pressure
R5818	T19674	T19672	dobj	pressure,have
R5819	T19675	T19674	compound	blood,pressure
R5820	T19723	T19721	prep	of,analysis
R5821	T19676	T19677	advmod	when,compared
R5822	T19677	T19672	advcl	compared,have
R5823	T19678	T19677	prep	to,compared
R5824	T19679	T19680	amod	WT,littermates
R5825	T19680	T19678	pobj	littermates,to
R5826	T19681	T19672	punct	", ",have
R5827	T19682	T19672	cc	and,have
R5828	T19724	T19725	det	the,tail
R5829	T19683	T19684	nmod	uPA,mice
R5830	T19725	T19723	pobj	tail,of
R5831	T19684	T19698	nsubj	mice,have
R5832	T19685	T19683	punct	-,uPA
R5833	T19726	T19727	det	a,difference
R5834	T19686	T19683	punct	/,uPA
R5835	T19687	T19683	punct	-,uPA
R5836	T19688	T19689	punct	[,37
R5837	T19689	T19683	parataxis	37,uPA
R5838	T19727	T19722	dobj	difference,indicated
R5839	T19690	T19689	punct	],37
R5840	T19691	T19683	cc	and,uPA
R5841	T19728	T19727	prep	in,difference
R5842	T19692	T19683	conj	Lepob,uPA
R5843	T19693	T19694	punct	[,39
R5844	T19694	T19692	parataxis	39,Lepob
R5845	T19729	T19730	det	the,content
R5846	T19695	T19694	nummod	38,39
R5847	T19696	T19694	punct	",",39
R5848	T19697	T19694	punct	],39
R5849	T19730	T19728	pobj	content,in
R5850	T19698	T19672	conj	have,have
R5851	T19699	T19698	advmod	also,have
R5852	T19700	T19701	amod	reduced,pressure
R5853	T19731	T19730	compound	collagen,content
R5854	T19701	T19698	dobj	pressure,have
R5855	T19702	T19701	compound	blood,pressure
R5856	T19703	T19643	punct	", ",measured
R5857	T19732	T19730	prep	of,content
R5858	T19704	T19643	cc	but,measured
R5859	T19705	T19706	expl	there,is
R5860	T19706	T19643	conj	is,measured
R5861	T19733	T19734	det	the,tail
R5862	T19707	T19708	det	no,correspondence
R5863	T19708	T19706	attr	correspondence,is
R5864	T19734	T19732	pobj	tail,of
R5865	T19709	T19708	prep	between,correspondence
R5866	T19710	T19711	compound	blood,pressure
R5867	T19735	T19727	prep	in,difference
R5868	T19736	T19737	det	the,mice
R5869	T19737	T19735	pobj	mice,in
R5870	T19738	T19739	compound	A,J
R5871	T19817	T19815	pobj	J,in
R5872	T19818	T19817	compound	A,J
R5873	T19739	T19737	compound	J,mice
R5874	T19819	T19817	punct	/,J
R5875	T19820	T19817	appos	mice,J
R5876	T19821	T19820	cc	and,mice
R5877	T19822	T19820	conj	CSS,mice
R5878	T19823	T19781	punct	.,reside
R5879	T19740	T19739	punct	/,J
R5880	T19825	T19826	nsubj	It,is
R5881	T19827	T19826	neg	not,is
R5882	T19828	T19826	acomp	likely,is
R5883	T19741	T19722	punct	.,indicated
R5884	T19829	T19830	mark	that,explains
R5885	T19830	T19826	ccomp	explains,is
R5886	T19743	T19744	nsubj	Differences,contribute
R5887	T19831	T19832	advmod	merely,concentration
R5888	T19832	T19830	nsubj	concentration,explains
R5889	T19833	T19832	det	the,concentration
R5890	T19834	T19832	prep	of,concentration
R5891	T19835	T19836	det	these,components
R5892	T19836	T19834	pobj	components,of
R5893	T19745	T19743	prep	in,Differences
R5894	T19837	T19838	det	the,time
R5895	T19838	T19830	dobj	time,explains
R5896	T19839	T19838	amod	increased,time
R5897	T19746	T19747	det	the,structure
R5898	T19747	T19745	pobj	structure,in
R5899	T19840	T19838	compound	rebleeding,time
R5900	T19748	T19747	cc	and,structure
R5901	T19841	T19838	cc	and,time
R5902	T19842	T19843	amod	reduced,time
R5903	T19749	T19748	punct	/,and
R5904	T19843	T19838	conj	time,time
R5905	T19844	T19845	amod	arterial,occlusion
R5906	T19845	T19843	compound	occlusion,time
R5907	T19750	T19748	cc	or,and
R5908	T19846	T19838	prep	in,time
R5909	T19847	T19848	det	the,mice
R5910	T19751	T19747	conj	metabolism,structure
R5911	T19848	T19846	pobj	mice,in
R5912	T19849	T19850	compound	A,J
R5913	T19850	T19848	compound	J,mice
R5914	T19752	T19747	prep	of,structure
R5915	T19851	T19850	punct	/,J
R5916	T19852	T19826	punct	.,is
R5917	T19753	T19752	pobj	collagen,of
R5918	T19854	T19855	advmod	When,compared
R5919	T19855	T19856	advcl	compared,had
R5920	T19754	T19753	cc	or,collagen
R5921	T19857	T19855	prep	to,compared
R5922	T19858	T19859	det	the,mice
R5923	T19755	T19756	amod	extracellular,proteins
R5924	T19859	T19857	pobj	mice,to
R5925	T19860	T19859	compound	B6,mice
R5926	T19861	T19856	punct	", ",had
R5927	T19756	T19753	conj	proteins,collagen
R5928	T19862	T19863	det	the,mice
R5929	T19863	T19856	nsubj	mice,had
R5930	T19864	T19865	compound	A,J
R5931	T19757	T19756	compound	matrix,proteins
R5932	T19865	T19863	compound	J,mice
R5933	T19866	T19865	punct	/,J
R5934	T19867	T19863	cc	and,mice
R5935	T19758	T19744	aux	may,contribute
R5936	T19868	T19869	det	the,strains
R5937	T19869	T19863	conj	strains,mice
R5938	T19870	T19869	nummod	three,strains
R5939	T19759	T19744	prep	to,contribute
R5940	T19871	T19863	prep	with,mice
R5941	T19872	T19873	amod	elevated,time
R5942	T19760	T19761	det	the,time
R5943	T19873	T19871	pobj	time,with
R5944	T19874	T19873	compound	rebleeding,time
R5945	T19875	T19876	amod	variable,Plg
R5946	T19761	T19759	pobj	time,to
R5947	T19876	T19856	dobj	Plg,had
R5948	T19877	T19876	punct	", ",Plg
R5949	T19762	T19763	amod	increased,rebleeding
R5950	T19878	T19876	conj	PAI,Plg
R5951	T19879	T19878	punct	-,PAI
R5952	T19880	T19878	nummod	1,PAI
R5953	T19881	T19878	punct	", ",PAI
R5954	T19763	T19761	nmod	rebleeding,time
R5955	T19882	T19878	cc	and,PAI
R5956	T19883	T19884	compound	α2,antiplasmin
R5957	T19884	T19878	conj	antiplasmin,PAI
R5958	T19764	T19763	cc	and,rebleeding
R5959	T19885	T19884	punct	-,antiplasmin
R5960	T19886	T19856	punct	.,had
R5961	T19765	T19766	nmod	reduced,occlusion
R5962	T19888	T19889	nummod	Two,forms
R5963	T19889	T19891	nsubjpass	forms,reported
R5964	T19766	T19763	conj	occlusion,rebleeding
R5965	T19890	T19889	amod	allelic,forms
R5966	T19892	T19889	prep	of,forms
R5967	T19767	T19744	prep	in,contribute
R5968	T19893	T19894	det	the,gene
R5969	T19894	T19892	pobj	gene,of
R5970	T19768	T19769	det	the,mice
R5971	T19895	T19894	compound	mouse,gene
R5972	T19896	T19894	compound	Plg,gene
R5973	T19897	T19891	aux	have,reported
R5974	T19898	T19891	auxpass	been,reported
R5975	T19769	T19767	pobj	mice,in
R5976	T19899	T19891	prep	for,reported
R5977	T19900	T19901	nmod	B6,mice
R5978	T19901	T19899	pobj	mice,for
R5979	T19902	T19900	cc	and,B6
R5980	T19903	T19904	compound	A,J
R5981	T19770	T19771	compound	A,J
R5982	T19904	T19900	conj	J,B6
R5983	T19905	T19904	punct	/,J
R5984	T19906	T19907	punct	[,40
R5985	T19907	T19891	parataxis	40,reported
R5986	T19771	T19769	compound	J,mice
R5987	T19908	T19907	punct	],40
R5988	T19909	T19891	punct	.,reported
R5989	T19772	T19771	punct	/,J
R5990	T19911	T19912	compound	Plg,concentration
R5991	T19912	T19913	nsubjpass	concentration,increased
R5992	T19773	T19744	cc	and,contribute
R5993	T19914	T19913	auxpass	was,increased
R5994	T19915	T19913	prep	in,increased
R5995	T19774	T19744	conj	warrant,contribute
R5996	T19916	T19917	compound	A,J
R5997	T19917	T19919	compound	J,mice
R5998	T19918	T19917	punct	/,J
R5999	T19775	T19776	amod	further,investigation
R6000	T19919	T19915	pobj	mice,in
R6001	T19920	T19913	prep	compared,increased
R6002	T19921	T19920	prep	to,compared
R6003	T19776	T19774	dobj	investigation,warrant
R6004	T19922	T19923	compound	B6,mice
R6005	T19777	T19744	punct	.,contribute
R6006	T19779	T19780	det	The,genes
R6007	T19923	T19921	pobj	mice,to
R6008	T19924	T19913	punct	.,increased
R6009	T19780	T19781	nsubj	genes,reside
R6010	T19926	T19927	mark	Although,detect
R6011	T19782	T19780	prep	for,genes
R6012	T19927	T19931	advcl	detect,exclude
R6013	T19928	T19927	nsubj	we,detect
R6014	T19929	T19927	aux	did,detect
R6015	T19930	T19927	neg	not,detect
R6016	T19783	T19782	pobj	Plg,for
R6017	T19932	T19927	dobj	differences,detect
R6018	T19784	T19783	punct	", ",Plg
R6019	T19933	T19932	prep	in,differences
R6020	T19934	T19935	compound	Plg,structure
R6021	T19935	T19933	pobj	structure,in
R6022	T19936	T19931	punct	", ",exclude
R6023	T19785	T19783	conj	PAI,Plg
R6024	T19937	T19931	nsubj	this,exclude
R6025	T19938	T19931	aux	would,exclude
R6026	T19786	T19785	punct	-,PAI
R6027	T19939	T19931	neg	not,exclude
R6028	T19940	T19941	amod	possible,differences
R6029	T19941	T19931	dobj	differences,exclude
R6030	T19942	T19941	amod	functional,differences
R6031	T19943	T19931	punct	.,exclude
R6032	T19787	T19785	nummod	1,PAI
R6033	T19945	T19946	det	A,strain
R6034	T19946	T19948	nsubjpass	strain,tested
R6035	T19947	T19946	amod	congenic,strain
R6036	T19788	T19785	punct	", ",PAI
R6037	T19949	T19946	punct	(,strain
R6038	T19789	T19785	cc	and,PAI
R6039	T19950	T19946	amod	specific,strain
R6040	T19790	T19791	compound	α2,antiplasmin
R6041	T19951	T19950	prep	for,specific
R6042	T19952	T19953	det	a,region
R6043	T19953	T19951	pobj	region,for
R6044	T19791	T19785	conj	antiplasmin,PAI
R6045	T19954	T19953	amod	homosomic,region
R6046	T19955	T19953	prep	from,region
R6047	T19956	T19957	compound	A,J
R6048	T19792	T19791	punct	-,antiplasmin
R6049	T19957	T19955	pobj	J,from
R6050	T19958	T19957	punct	/,J
R6051	T19793	T19781	prep	on,reside
R6052	T19959	T19957	cc	and,J
R6053	T19960	T19961	det	the,Chr
R6054	T19961	T19957	conj	Chr,J
R6055	T19794	T19795	det	the,chromosomes
R6056	T19962	T19961	amod	remaining,Chr
R6057	T19963	T19964	cc	and,is
R6058	T19964	T19953	parataxis	is,region
R6059	T19795	T19793	pobj	chromosomes,on
R6060	T19965	T19964	nsubj	background,is
R6061	T19966	T19964	prep	from,is
R6062	T19967	T19968	compound	B6,mice
R6063	T19796	T19795	nummod	three,chromosomes
R6064	T19968	T19966	pobj	mice,from
R6065	T19969	T19964	punct	),is
R6066	T19970	T19946	prep	of,strain
R6067	T19797	T19795	acl	identified,chromosomes
R6068	T19971	T19972	compound	A,J
R6069	T19972	T19974	compound	J,chromosome
R6070	T19798	T19797	prep	for,identified
R6071	T19973	T19972	punct	/,J
R6072	T19974	T19970	pobj	chromosome,of
R6073	T19975	T19974	nummod	17,chromosome
R6074	T19799	T19798	pobj	QTL,for
R6075	T19976	T19977	dep	that,includes
R6076	T19977	T19946	relcl	includes,strain
R6077	T19978	T19979	det	the,gene
R6078	T19800	T19799	prep	for,QTL
R6079	T19979	T19977	dobj	gene,includes
R6080	T19980	T19979	compound	Plg,gene
R6081	T19981	T19948	auxpass	was,tested
R6082	T19982	T19948	prep	in,tested
R6083	T19983	T19984	det	the,assay
R6084	T19984	T19982	pobj	assay,in
R6085	T19801	T19802	compound	rebleeding,time
R6086	T19985	T19984	compound	bleeding,assay
R6087	T19986	T19948	punct	.,tested
R6088	T19802	T19800	pobj	time,for
R6089	T19988	T19989	nsubj	Values,were
R6090	T19990	T19988	prep	for,Values
R6091	T19803	T19781	cc	and,reside
R6092	T19991	T19990	pobj	bleeding,for
R6093	T19992	T19991	cc	and,bleeding
R6094	T19993	T19991	conj	rebleeding,bleeding
R6095	T19804	T19781	conj	may,reside
R6096	T19994	T19988	prep	in,Values
R6097	T19995	T19996	det	this,strain
R6098	T19996	T19994	pobj	strain,in
R6099	T19805	T19804	cc	or,may
R6100	T19997	T19996	amod	congenic,strain
R6101	T19998	T19989	acomp	similar,were
R6102	T19999	T19998	prep	to,similar
R6103	T19806	T19804	conj	may,may
R6104	T20000	T19999	pobj	values,to
R6105	T20001	T20000	prep	from,values
R6106	T20002	T20003	compound	B6,mice
R6107	T19807	T19806	neg	not,may
R6108	T20003	T20001	pobj	mice,from
R6109	T20004	T19989	punct	", ",were
R6110	T20005	T19989	advcl	indicating,were
R6111	T19808	T19806	dep	be,may
R6112	T20006	T20007	mark	that,is
R6113	T20007	T20005	ccomp	is,indicating
R6114	T20008	T20009	det	the,QTL
R6115	T19809	T19808	acomp	coincidental,be
R6116	T20009	T20007	nsubj	QTL,is
R6117	T20010	T20007	neg	not,is
R6118	T20011	T20007	attr	Plg,is
R6119	T19810	T19809	prep	to,coincidental
R6120	T20012	T19989	punct	.,were
R6121	T20014	T20015	expl	There,are
R6122	T19811	T19812	det	the,phenotypes
R6123	T20016	T20015	attr	genes,are
R6124	T20017	T20016	prep	for,genes
R6125	T19812	T19810	pobj	phenotypes,to
R6126	T20018	T20019	amod	other,proteases
R6127	T20019	T20017	pobj	proteases,for
R6128	T19813	T19812	amod	observed,phenotypes
R6129	T20020	T20019	cc	and,proteases
R6130	T20021	T20022	compound	matrix,proteins
R6131	T20022	T20019	conj	proteins,proteases
R6132	T19814	T19812	acl	found,phenotypes
R6133	T20023	T20024	dep	that,reside
R6134	T20024	T20019	relcl	reside,proteases
R6135	T20025	T20024	prep	on,reside
R6136	T20026	T20025	pobj	chromosome,on
R6137	T20027	T20026	nummod	17,chromosome
R6138	T20028	T20015	prep	in,are
R6139	T19815	T19814	prep	in,found
R6140	T19816	T19817	det	the,J
R6142	T20029	T20028	pobj	addition,in
R6143	T20030	T20029	prep	to,addition
R6144	T20031	T20032	amod	unknown,genes
R6145	T20032	T20030	pobj	genes,to
R6147	T20033	T20015	punct	.,are
R6149	T20035	T20036	compound	DNA,data
R6151	T20036	T20040	nsubj	data,reported
R6152	T20037	T20038	compound	base,sequence
R6154	T20038	T20036	compound	sequence,data
R6155	T20039	T20038	compound	pair,sequence
R6157	T20041	T20036	prep	for,data
R6158	T20042	T20043	det	the,gene
R6160	T20043	T20041	pobj	gene,for
R6161	T20044	T20043	nmod	PAI,gene
R6163	T20045	T20044	punct	-,PAI
R6164	T20046	T20044	nummod	1,PAI
R6167	T20047	T20043	cc	or,gene
R6169	T20048	T20049	det	the,gene
R6170	T20049	T20043	conj	gene,gene
R6172	T20050	T20051	compound	α2,antiplasmin
R6173	T20051	T20049	compound	antiplasmin,gene
R6174	T20052	T20051	punct	-,antiplasmin
R6176	T20053	T20036	prep	in,data
R6177	T20054	T20055	nmod	B6,mice
R6179	T20055	T20053	pobj	mice,in
R6180	T20056	T20054	cc	and,B6
R6181	T20057	T20058	compound	A,J
R6182	T20058	T20054	conj	J,B6
R6184	T20059	T20058	punct	/,J
R6185	T20060	T20040	aux	have,reported
R6186	T20061	T20062	det	no,differences
R6187	T20062	T20040	dobj	differences,reported
R6188	T20063	T20064	punct	[,51
R6189	T20064	T20040	parataxis	51,reported
R6191	T20065	T20064	punct	],51
R6192	T20066	T20040	punct	", ",reported
R6193	T20067	T20040	cc	but,reported
R6195	T20068	T20069	amod	regulatory,genes
R6196	T20069	T20070	nsubj	genes,be
R6197	T20070	T20040	conj	be,reported
R6198	T20071	T20069	advmod	upstream,genes
R6200	T20072	T20071	prep	of,upstream
R6201	T20073	T20074	det	the,region
R6202	T20074	T20072	pobj	region,of
R6204	T20075	T20074	amod	coding,region
R6205	T20076	T20070	aux	may,be
R6206	T20077	T20070	acomp	important,be
R6207	T20078	T20070	punct	.,be
R6209	T20080	T20081	poss	Our,results
R6210	T20081	T20082	nsubj	results,suggest
R6211	T20157	T20159	compound	J,mice
R6212	T20083	T20084	mark	that,interact
R6213	T20084	T20082	ccomp	interact,suggest
R6214	T20158	T20157	punct	/,J
R6215	T20085	T20086	amod	novel,genes
R6216	T20086	T20084	nsubj	genes,interact
R6217	T20087	T20085	cc	or,novel
R6218	T20159	T20155	pobj	mice,from
R6219	T20088	T20085	conj	unknown,novel
R6220	T20089	T20084	aux	may,interact
R6221	T20090	T20084	prep	with,interact
R6222	T20160	T20154	auxpass	were,identified
R6223	T20091	T20092	det	the,components
R6224	T20092	T20090	pobj	components,with
R6225	T20093	T20094	compound	Plg,system
R6226	T20161	T20162	dep	that,had
R6227	T20094	T20092	compound	system,components
R6228	T20095	T20096	aux	to,modify
R6229	T20096	T20084	advcl	modify,interact
R6230	T20162	T20154	ccomp	had,identified
R6231	T20097	T20098	poss	their,function
R6232	T20098	T20096	dobj	function,modify
R6233	T20099	T20082	punct	.,suggest
R6234	T20163	T20162	dobj	QTL,had
R6235	T20101	T20102	prep	In,reports
R6236	T20164	T20163	prep	for,QTL
R6237	T20103	T20101	pobj	summary,In
R6238	T20104	T20102	punct	", ",reports
R6239	T20105	T20106	det	this,study
R6240	T20106	T20102	nsubj	study,reports
R6241	T20107	T20108	amod	marked,differences
R6242	T20108	T20102	dobj	differences,reports
R6243	T20165	T20166	compound	rebleeding,time
R6244	T20109	T20108	prep	in,differences
R6245	T20110	T20111	nummod	two,strains
R6246	T20111	T20109	pobj	strains,in
R6247	T20112	T20111	amod	inbred,strains
R6248	T20166	T20164	pobj	time,for
R6249	T20113	T20111	prep	of,strains
R6250	T20114	T20113	pobj	mice,of
R6251	T20115	T20111	punct	", ",strains
R6252	T20167	T20154	punct	.,identified
R6253	T20116	T20111	appos	B6,strains
R6254	T20117	T20116	cc	and,B6
R6255	T20118	T20119	compound	A,J
R6256	T20169	T20170	det	The,genes
R6257	T20119	T20116	conj	J,B6
R6258	T20120	T20119	punct	/,J
R6259	T20170	T20171	nsubj	genes,interact
R6260	T20172	T20171	aux	may,interact
R6261	T20121	T20108	punct	", ",differences
R6262	T20122	T20108	prep	in,differences
R6263	T20123	T20124	amod	arterial,thrombosis
R6264	T20124	T20125	compound	thrombosis,formation
R6265	T20173	T20171	prep	with,interact
R6266	T20125	T20122	pobj	formation,in
R6267	T20126	T20125	prep	in,formation
R6268	T20127	T20128	det	a,model
R6269	T20174	T20173	pobj	components,with
R6270	T20128	T20126	pobj	model,in
R6271	T20175	T20174	prep	in,components
R6272	T20129	T20128	nmod	FeCl3,model
R6273	T20130	T20131	amod	vascular,injury
R6274	T20131	T20128	compound	injury,model
R6275	T20132	T20125	punct	", ",formation
R6276	T20176	T20177	det	the,network
R6277	T20133	T20134	compound	rebleeding,time
R6278	T20134	T20125	conj	time,formation
R6279	T20177	T20175	pobj	network,in
R6280	T20178	T20177	compound	Plg,network
R6281	T20179	T20171	cc	and,interact
R6282	T20180	T20171	conj	modulate,interact
R6283	T20181	T20182	amod	arterial,occlusion
R6284	T20182	T20183	compound	occlusion,time
R6285	T20183	T20180	dobj	time,modulate
R6286	T20184	T20171	punct	.,interact
R6287	T20400	T20401	det	The,differences
R6288	T20401	T20404	nsubjpass	differences,exploited
R6289	T20402	T20401	amod	marked,differences
R6290	T20403	T20401	amod	independent,differences
R6291	T20405	T20401	acl	demonstrated,differences
R6292	T20406	T20405	prep	in,demonstrated
R6293	T20407	T20408	det	the,mice
R6294	T20408	T20406	pobj	mice,in
R6295	T20409	T20408	nmod	B6,mice
R6296	T20410	T20409	cc	and,B6
R6297	T20411	T20412	compound	A,J
R6298	T20412	T20409	conj	J,B6
R6299	T20413	T20412	punct	/,J
R6300	T20414	T20404	aux	can,exploited
R6301	T20415	T20404	auxpass	be,exploited
R6302	T20416	T20417	aux	to,identify
R6303	T20417	T20404	advcl	identify,exploited
R6304	T20418	T20419	amod	genetic,determinants
R6305	T20419	T20417	dobj	determinants,identify
R6306	T20420	T20419	prep	of,determinants
R6307	T20421	T20420	pobj	thrombosis,of
R6308	T20422	T20421	cc	and,thrombosis
R6309	T20423	T20421	conj	haemostasis,thrombosis
R6310	T20424	T20404	punct	.,exploited
R6311	T20426	T20427	poss	Our,results
R6312	T20427	T20428	nsubj	results,suggest
R6313	T20429	T20427	prep	of,results
R6314	T20430	T20431	det	the,screening
R6315	T20431	T20429	pobj	screening,of
R6316	T20432	T20431	compound	CSS,screening
R6317	T20433	T20434	mark	that,used
R6318	T20434	T20428	ccomp	used,suggest
R6319	T20435	T20436	amod	novel,genes
R6320	T20436	T20434	nsubjpass	genes,used
R6321	T20437	T20435	cc	or,novel
R6322	T20438	T20435	conj	unknown,novel
R6323	T20439	T20434	aux	can,used
R6324	T20440	T20434	auxpass	be,used
R6325	T20441	T20442	aux	to,identify
R6326	T20442	T20434	advcl	identify,used
R6327	T20443	T20444	det	the,genes
R6328	T20444	T20442	dobj	genes,identify
R6329	T20445	T20444	amod	responsible,genes
R6330	T20446	T20445	prep	for,responsible
R6331	T20447	T20448	det	the,traits
R6332	T20448	T20446	pobj	traits,for
R6333	T20449	T20448	amod	related,traits
R6334	T20450	T20449	prep	to,related
R6335	T20451	T20452	amod	arterial,thrombosis
R6336	T20452	T20450	pobj	thrombosis,to
R6337	T20453	T20448	punct	", ",traits
R6338	T20454	T20455	compound	tail,rebleeding
R6339	T20455	T20448	appos	rebleeding,traits
R6340	T20456	T20455	compound	bleeding,rebleeding
R6341	T20457	T20455	punct	/,rebleeding
R6342	T20458	T20455	cc	and,rebleeding
R6343	T20459	T20460	nmod	vessel,matrix
R6344	T20460	T20455	conj	matrix,rebleeding
R6345	T20461	T20460	amod	extracellular,matrix
R6346	T20462	T20428	punct	.,suggest
R6347	T20464	T20465	nsubj	Identification,is
R6348	T20466	T20464	prep	of,Identification
R6349	T20467	T20466	pobj	differences,of
R6350	T20468	T20467	prep	in,differences
R6351	T20469	T20470	det	the,strains
R6352	T20470	T20468	pobj	strains,in
R6353	T20471	T20470	compound	parent,strains
R6354	T20472	T20467	punct	", ",differences
R6355	T20473	T20474	amod	such,as
R6356	T20474	T20467	prep	as,differences
R6357	T20475	T20474	pobj	those,as
R6358	T20476	T20475	acl	described,those
R6359	T20477	T20476	prep	in,described
R6360	T20478	T20479	det	this,study
R6361	T20479	T20477	pobj	study,in
R6362	T20480	T20464	punct	", ",Identification
R6363	T20481	T20464	cc	and,Identification
R6364	T20482	T20464	conj	screening,Identification
R6365	T20483	T20482	prep	of,screening
R6366	T20484	T20485	det	the,CSS
R6367	T20485	T20483	pobj	CSS,of
R6368	T20486	T20487	det	a,step
R6369	T20487	T20465	attr	step,is
R6370	T20488	T20487	amod	first,step
R6371	T20489	T20487	punct	-,step
R6372	T20490	T20487	prep	in,step
R6373	T20491	T20492	det	the,discovery
R6374	T20492	T20490	pobj	discovery,in
R6375	T20493	T20492	prep	of,discovery
R6376	T20494	T20495	amod	new,determinants
R6377	T20495	T20493	pobj	determinants,of
R6378	T20496	T20495	amod	genetic,determinants
R6379	T20497	T20495	prep	of,determinants
R6380	T20498	T20499	amod	thrombotic,risk
R6381	T20499	T20497	pobj	risk,of
R6382	T20500	T20465	punct	.,is
R6383	T20522	T20523	det	The,history
R6384	T20523	T20525	nsubjpass	history,accessed
R6385	T20524	T20523	amod	pre-publication,history
R6386	T20526	T20523	prep	for,history
R6387	T20527	T20528	det	this,paper
R6388	T20528	T20526	pobj	paper,for
R6389	T20529	T20525	aux	can,accessed
R6390	T20530	T20525	auxpass	be,accessed
R6391	T20531	T20525	advmod	here,accessed
R6392	T20532	T20525	punct	:,accessed
R6393	T20565	T20564	prep	of,Identification
R6394	T20566	T20565	pobj	mice,of
R6395	T20567	T20566	amod	susceptible,mice
R6396	T20568	T20567	cc	or,susceptible
R6397	T20569	T20567	conj	resistant,susceptible
R6398	T20570	T20569	prep	to,resistant
R6399	T20571	T20570	pobj	obesity,to
R6400	T20572	T20571	punct	", ",obesity
R6401	T20573	T20571	conj	atherosclerosis,obesity
R6402	T20574	T20573	punct	", ",atherosclerosis
R6403	T20575	T20573	cc	and,atherosclerosis
R6404	T20576	T20577	amod	vascular,injury
R6405	T20577	T20573	conj	injury,atherosclerosis
R6406	T20771	T20772	amod	Arterial,occlusion
R6407	T20772	T20773	compound	occlusion,time
R6408	T20774	T20773	prep	in,time
R6409	T20775	T20776	nmod	B6,mice
R6410	T20776	T20774	pobj	mice,in
R6411	T20777	T20775	cc	and,B6
R6412	T20778	T20779	compound	A,J
R6413	T20779	T20775	conj	J,B6
R6414	T20780	T20779	punct	/,J
R6415	T20781	T20773	punct	.,time
R6416	T20783	T20784	compound	Panels,A
R6417	T20784	T20785	nsubj	A,are
R6418	T20786	T20784	cc	and,A
R6419	T20787	T20784	conj	B,A
R6420	T20788	T20789	amod	representative,curves
R6421	T20789	T20785	attr	curves,are
R6422	T20790	T20789	compound	occlusion,curves
R6423	T20791	T20789	prep	from,curves
R6424	T20792	T20793	det	each,genotype
R6425	T20793	T20791	pobj	genotype,from
R6426	T20794	T20785	punct	.,are
R6427	T20796	T20797	amod	Red,arrows
R6428	T20797	T20798	nsubj	arrows,indicate
R6429	T20799	T20798	dobj	duration,indicate
R6430	T20800	T20799	prep	of,duration
R6431	T20801	T20802	amod	ferric,chloride
R6432	T20802	T20803	compound	chloride,application
R6433	T20803	T20800	pobj	application,of
R6434	T20804	T20803	prep	to,application
R6435	T20805	T20806	det	the,carotid
R6436	T20806	T20804	pobj	carotid,to
R6437	T20807	T20798	punct	.,indicate
R6438	T20809	T20810	compound	Panel,A
R6439	T20811	T20810	punct	: ,A
R6440	T20812	T20813	compound	B6,mice
R6441	T20813	T20810	appos	mice,A
R6442	T20814	T20810	punct	", ",A
R6443	T20815	T20816	compound	Panel,B
R6444	T20816	T20810	appos	B,A
R6445	T20817	T20816	punct	: ,B
R6446	T20818	T20819	compound	A,J
R6447	T20819	T20821	compound	J,mice
R6448	T20820	T20819	punct	/,J
R6449	T20821	T20816	appos	mice,B
R6450	T20822	T20810	punct	.,A
R6451	T20824	T20825	compound	Panel,C
R6452	T20826	T20825	punct	: ,C
R6453	T20827	T20828	amod	Arterial,occlusion
R6454	T20828	T20829	compound	occlusion,time
R6455	T20829	T20825	appos	time,C
R6456	T20830	T20829	punct	", ",time
R6457	T20831	T20832	nmod	mean,SEM
R6458	T20832	T20829	appos	SEM,time
R6459	T20833	T20832	punct	±,SEM
R6460	T20834	T20832	prep	of,SEM
R6461	T20835	T20836	compound	14,17
R6462	T20836	T20838	nummod	17,mice
R6463	T20837	T20836	punct	–,17
R6464	T20838	T20834	pobj	mice,of
R6465	T20839	T20838	prep	per,mice
R6466	T20840	T20839	pobj	genotype,per
R6467	T20841	T20825	punct	.,C
R6468	T20843	T20844	nsubj	Symbol,indicates
R6469	T20845	T20846	det	a,difference
R6470	T20846	T20844	dobj	difference,indicates
R6471	T20847	T20846	amod	significant,difference
R6472	T20848	T20849	punct	(,0.01
R6473	T20849	T20846	parataxis	0.01,difference
R6474	T20850	T20851	punct	**,P
R6475	T20851	T20849	nsubj	P,0.01
R6476	T20852	T20849	punct	<,0.01
R6477	T20853	T20849	punct	),0.01
R6478	T20854	T20846	prep	between,difference
R6479	T20855	T20856	compound	B6,mice
R6480	T20856	T20854	pobj	mice,between
R6481	T20857	T20846	acl	determined,difference
R6482	T20858	T20857	prep	with,determined
R6483	T20859	T20860	det	a,test
R6484	T20860	T20858	pobj	test,with
R6485	T20861	T20860	compound	t,test
R6486	T20862	T20860	punct	-,test
R6487	T20863	T20844	punct	.,indicates
R6488	T21152	T21153	nmod	Bleeding,time
R6489	T21154	T21152	cc	and,Bleeding
R6490	T21155	T21152	conj	rebleeding,Bleeding
R6491	T21156	T21153	prep	in,time
R6492	T21157	T21158	nmod	B6,mice
R6493	T21158	T21156	pobj	mice,in
R6494	T21159	T21157	punct	", ",B6
R6495	T21160	T21161	compound	A,J
R6496	T21161	T21157	conj	J,B6
R6497	T21162	T21161	punct	/,J
R6498	T21163	T21161	punct	", ",J
R6499	T21164	T21161	conj	Lepob,J
R6500	T21165	T21164	punct	", ",Lepob
R6501	T21166	T21164	conj	Plg,Lepob
R6502	T21167	T21166	punct	-,Plg
R6503	T21168	T21166	punct	/,Plg
R6504	T21169	T21166	punct	-,Plg
R6505	T21170	T21166	cc	and,Plg
R6506	T21171	T21166	conj	PAI,Plg
R6507	T21172	T21171	punct	-,PAI
R6508	T21173	T21171	nummod	1,PAI
R6509	T21174	T21171	punct	-,PAI
R6510	T21175	T21171	punct	/,PAI
R6511	T21176	T21171	punct	-,PAI
R6512	T21177	T21153	punct	.,time
R6513	T21179	T21180	nmod	Panel,B
R6514	T21180	T21183	dep	B,time
R6515	T21181	T21180	nmod	A,B
R6516	T21182	T21180	punct	", ",B
R6517	T21184	T21183	punct	: ,time
R6518	T21185	T21183	compound	Bleeding,time
R6519	T21186	T21187	punct	(,seconds
R6520	T21187	T21183	parataxis	seconds,time
R6521	T21188	T21187	punct	),seconds
R6522	T21189	T21183	cc	and,time
R6523	T21190	T21191	nmod	Panel,D
R6524	T21191	T21194	dep	D,time
R6525	T21192	T21191	nmod	C,D
R6526	T21193	T21191	punct	", ",D
R6527	T21194	T21183	conj	time,time
R6528	T21195	T21194	punct	: ,time
R6529	T21196	T21194	compound	Rebleeding,time
R6530	T21197	T21198	punct	(,seconds
R6531	T21198	T21194	parataxis	seconds,time
R6532	T21199	T21198	punct	),seconds
R6533	T21200	T21194	punct	.,time
R6534	T21202	T21203	aux	To,determine
R6535	T21203	T21204	advcl	determine,compared
R6536	T21205	T21206	amod	statistical,differences
R6537	T21206	T21203	dobj	differences,determine
R6538	T21207	T21204	punct	", ",compared
R6539	T21208	T21204	nsubjpass	values,compared
R6540	T21209	T21208	prep	from,values
R6541	T21210	T21209	pobj	B6,from
R6542	T21211	T21210	cc	and,B6
R6543	T21212	T21213	compound	A,J
R6544	T21213	T21210	conj	J,B6
R6545	T21214	T21213	punct	/,J
R6546	T21215	T21209	cc	and,from
R6547	T21216	T21209	conj	from,from
R6548	T21217	T21216	pobj	WT,from
R6549	T21218	T21217	cc	and,WT
R6550	T21219	T21217	conj	Plg,WT
R6551	T21220	T21219	punct	-,Plg
R6552	T21221	T21219	punct	/,Plg
R6553	T21222	T21219	punct	-,Plg
R6554	T21223	T21216	pobj	littermates,from
R6555	T21224	T21204	auxpass	were,compared
R6556	T21225	T21204	prep	with,compared
R6557	T21226	T21227	det	a,test
R6558	T21227	T21225	pobj	test,with
R6559	T21228	T21227	compound	t,test
R6560	T21229	T21227	punct	-,test
R6561	T21230	T21204	punct	", ",compared
R6562	T21231	T21204	cc	and,compared
R6563	T21232	T21233	nsubjpass	values,compared
R6564	T21233	T21204	conj	compared,compared
R6565	T21234	T21232	prep	from,values
R6566	T21235	T21234	pobj	B6,from
R6567	T21236	T21235	punct	", ",B6
R6568	T21237	T21235	conj	PAI,B6
R6569	T21238	T21237	punct	-,PAI
R6570	T21239	T21237	nummod	1,PAI
R6571	T21240	T21237	punct	-,PAI
R6572	T21241	T21237	punct	/,PAI
R6573	T21242	T21237	punct	-,PAI
R6574	T21243	T21237	cc	and,PAI
R6575	T21244	T21237	conj	Lepob,PAI
R6576	T21245	T21233	auxpass	were,compared
R6577	T21246	T21233	prep	by,compared
R6578	T21247	T21248	det	a,ANOVA
R6579	T21248	T21246	pobj	ANOVA,by
R6580	T21249	T21250	nummod	one,way
R6581	T21250	T21248	compound	way,ANOVA
R6582	T21251	T21250	punct	-,way
R6583	T21252	T21248	cc	and,ANOVA
R6584	T21253	T21254	det	a,post-test
R6585	T21254	T21248	conj	post-test,ANOVA
R6586	T21255	T21256	compound	Newman,Keuls
R6587	T21256	T21254	compound	Keuls,post-test
R6588	T21257	T21256	punct	-,Keuls
R6589	T21258	T21233	punct	.,compared
R6590	T21260	T21261	nsubj	Symbols,indicate
R6591	T21262	T21263	det	a,difference
R6592	T21263	T21261	dobj	difference,indicate
R6593	T21264	T21263	amod	significant,difference
R6594	T21265	T21266	punct	(,0.001
R6595	T21266	T21263	parataxis	0.001,difference
R6596	T21267	T21268	punct	*,P
R6597	T21268	T21269	nsubj	P,0.05
R6598	T21269	T21266	ccomp	0.05,0.001
R6599	T21270	T21269	punct	<,0.05
R6600	T21271	T21266	punct	", ",0.001
R6601	T21272	T21273	punct	**,P
R6602	T21273	T21274	nsubj	P,0.01
R6603	T21274	T21266	ccomp	0.01,0.001
R6604	T21275	T21274	punct	<,0.01
R6605	T21276	T21266	punct	", ",0.001
R6606	T21277	T21278	punct	***,P
R6607	T21278	T21266	nsubj	P,0.001
R6608	T21279	T21266	punct	<,0.001
R6609	T21280	T21266	punct	),0.001
R6610	T21281	T21263	prep	between,difference
R6611	T21282	T21283	nmod	B6,mice
R6612	T21283	T21281	pobj	mice,between
R6613	T21284	T21282	cc	or,B6
R6614	T21285	T21282	conj	WT,B6
R6615	T21286	T21261	punct	.,indicate
R6616	T21288	T21289	nsubj	Values,are
R6617	T21290	T21291	det	the,SEM
R6618	T21291	T21289	attr	SEM,are
R6619	T21292	T21291	nmod	mean,SEM
R6620	T21293	T21291	punct	±,SEM
R6621	T21294	T21291	prep	of,SEM
R6622	T21295	T21296	quantmod	10,34
R6623	T21296	T21298	nummod	34,mice
R6624	T21297	T21296	punct	–,34
R6625	T21298	T21294	pobj	mice,of
R6626	T21299	T21298	prep	per,mice
R6627	T21300	T21299	pobj	genotype,per
R6628	T21301	T21289	punct	.,are
R6629	T21612	T21613	compound	Tail,morphology
R6630	T21614	T21613	cc	and,morphology
R6631	T21615	T21613	conj	collagen,morphology
R6632	T21616	T21615	punct	.,collagen
R6633	T21618	T21619	nsubjpass	Tails,excised
R6634	T21620	T21619	auxpass	were,excised
R6635	T21621	T21619	punct	", ",excised
R6636	T21622	T21619	conj	embedded,excised
R6637	T21623	T21622	prep	in,embedded
R6638	T21624	T21623	pobj	OCT,in
R6639	T21625	T21622	punct	", ",embedded
R6640	T21626	T21622	conj	sectioned,embedded
R6641	T21627	T21626	punct	", ",sectioned
R6642	T21628	T21626	cc	and,sectioned
R6643	T21629	T21626	conj	stained,sectioned
R6644	T21630	T21629	prep	with,stained
R6645	T21631	T21632	compound	Hematoxylin,Eosin
R6646	T21632	T21630	pobj	Eosin,with
R6647	T21633	T21632	punct	/,Eosin
R6648	T21634	T21632	cc	or,Eosin
R6649	T21635	T21636	poss	Masson,Trichrome
R6650	T21636	T21632	conj	Trichrome,Eosin
R6651	T21637	T21635	case	's,Masson
R6652	T21638	T21619	punct	.,excised
R6653	T21640	T21641	compound	Panel,A
R6654	T21642	T21641	punct	: ,A
R6655	T21643	T21644	amod	Representative,sections
R6656	T21644	T21641	appos	sections,A
R6657	T21645	T21644	acl	stained,sections
R6658	T21646	T21645	prep	with,stained
R6659	T21647	T21646	pobj	hematoxylin,with
R6660	T21648	T21647	cc	and,hematoxylin
R6661	T21649	T21647	conj	eosin,hematoxylin
R6662	T21650	T21644	prep	from,sections
R6663	T21651	T21652	nmod	B6,mice
R6664	T21652	T21650	pobj	mice,from
R6665	T21653	T21651	cc	and,B6
R6666	T21654	T21655	compound	A,J
R6667	T21655	T21651	conj	J,B6
R6668	T21656	T21655	punct	/,J
R6669	T21657	T21641	punct	.,A
R6670	T21659	T21660	compound	Panel,B
R6671	T21661	T21660	punct	: ,B
R6672	T21662	T21663	amod	Representative,sections
R6673	T21663	T21660	appos	sections,B
R6674	T21664	T21663	acl	stained,sections
R6675	T21665	T21664	prep	with,stained
R6676	T21666	T21667	poss	Masson,Trichrome
R6677	T21667	T21665	pobj	Trichrome,with
R6678	T21668	T21666	case	's,Masson
R6679	T21669	T21663	prep	from,sections
R6680	T21670	T21671	nmod	B6,mice
R6681	T21671	T21669	pobj	mice,from
R6682	T21672	T21670	cc	and,B6
R6683	T21673	T21674	compound	A,J
R6684	T21674	T21670	conj	J,B6
R6685	T21675	T21674	punct	/,J
R6686	T21676	T21660	punct	.,B
R6687	T21678	T21679	det	The,color
R6688	T21679	T21681	nsubj	color,identifies
R6689	T21680	T21679	amod	blue,color
R6690	T21682	T21683	det	the,collagen
R6691	T21683	T21681	dobj	collagen,identifies
R6692	T21684	T21681	punct	.,identifies
R6693	T21686	T21687	compound	Panel,C
R6694	T21687	T21688	dep	C,determined
R6695	T21689	T21688	punct	: ,determined
R6696	T21690	T21691	det	The,percentage
R6697	T21691	T21688	nsubjpass	percentage,determined
R6698	T21692	T21691	prep	of,percentage
R6699	T21693	T21694	det	the,area
R6700	T21694	T21692	pobj	area,of
R6701	T21695	T21694	compound	collagen,area
R6702	T21696	T21694	punct	(,area
R6703	T21697	T21694	acl	excluding,area
R6704	T21698	T21699	compound	center,bone
R6705	T21699	T21697	dobj	bone,excluding
R6706	T21700	T21699	punct	/,bone
R6707	T21701	T21699	appos	cartilage,bone
R6708	T21702	T21691	punct	),percentage
R6709	T21703	T21691	prep	of,percentage
R6710	T21704	T21705	det	the,area
R6711	T21705	T21703	pobj	area,of
R6712	T21706	T21705	amod	total,area
R6713	T21707	T21705	compound	tail,area
R6714	T21708	T21705	prep	of,area
R6715	T21709	T21710	det	each,section
R6716	T21710	T21708	pobj	section,of
R6717	T21711	T21688	auxpass	was,determined
R6718	T21712	T21688	prep	in,determined
R6719	T21713	T21714	quantmod	3,4
R6720	T21714	T21716	nummod	4,sections
R6721	T21715	T21714	punct	–,4
R6722	T21716	T21712	pobj	sections,in
R6723	T21717	T21688	prep	at,determined
R6724	T21718	T21719	quantmod	2,3
R6725	T21719	T21721	nummod	3,sites
R6726	T21720	T21719	punct	–,3
R6727	T21721	T21717	pobj	sites,at
R6728	T21722	T21721	prep	for,sites
R6729	T21723	T21724	det	each,tail
R6730	T21724	T21722	pobj	tail,for
R6731	T21725	T21688	cc	and,determined
R6732	T21726	T21688	conj	averaged,determined
R6733	T21727	T21726	prep	for,averaged
R6734	T21728	T21729	det	each,mouse
R6735	T21729	T21727	pobj	mouse,for
R6736	T21730	T21688	punct	.,determined
R6737	T21732	T21733	nsubj	Values,are
R6738	T21734	T21735	det	the,SEM
R6739	T21735	T21733	attr	SEM,are
R6740	T21736	T21735	nmod	mean,SEM
R6741	T21737	T21735	punct	±,SEM
R6742	T21738	T21735	prep	of,SEM
R6743	T21739	T21740	quantmod	4,8
R6744	T21740	T21742	nummod	8,mice
R6745	T21741	T21740	punct	–,8
R6746	T21742	T21738	pobj	mice,of
R6747	T21743	T21742	prep	per,mice
R6748	T21744	T21743	pobj	genotype,per
R6749	T21745	T21733	punct	.,are
R6750	T21747	T21748	nsubj	Symbol,indicates
R6751	T21749	T21750	det	a,difference
R6752	T21750	T21748	dobj	difference,indicates
R6753	T21751	T21750	amod	significant,difference
R6754	T21752	T21753	punct	(,0.05
R6755	T21753	T21750	parataxis	0.05,difference
R6756	T21754	T21755	punct	*,P
R6757	T21755	T21753	nsubj	P,0.05
R6758	T21756	T21753	punct	<,0.05
R6759	T21757	T21753	punct	),0.05
R6760	T21758	T21750	prep	between,difference
R6761	T21759	T21760	compound	B6,mice
R6762	T21760	T21758	pobj	mice,between
R6763	T21761	T21750	acl	determined,difference
R6764	T21762	T21761	agent	by,determined
R6765	T21763	T21764	compound	t,test
R6766	T21764	T21762	pobj	test,by
R6767	T21765	T21764	punct	-,test
R6768	T21766	T21748	punct	.,indicates
R6769	T21929	T21930	nmod	Bleeding,time
R6770	T21931	T21929	cc	and,Bleeding
R6771	T21932	T21929	conj	rebleeding,Bleeding
R6772	T21933	T21930	prep	in,time
R6773	T21934	T21935	det	the,CSS
R6774	T21935	T21933	pobj	CSS,in
R6775	T21936	T21930	punct	.,time
R6776	T21938	T21939	compound	Panel,A
R6777	T21940	T21939	punct	: ,A
R6778	T21941	T21942	compound	Bleeding,Time
R6779	T21942	T21939	appos	Time,A
R6780	T21943	T21944	punct	(,seconds
R6781	T21944	T21942	parataxis	seconds,Time
R6782	T21945	T21944	punct	),seconds
R6783	T21946	T21939	punct	.,A
R6784	T21948	T21949	compound	Panel,B
R6785	T21950	T21949	punct	: ,B
R6786	T21951	T21952	compound	Rebleeding,Time
R6787	T21952	T21949	appos	Time,B
R6788	T21953	T21954	punct	(,seconds
R6789	T21954	T21952	parataxis	seconds,Time
R6790	T21955	T21954	punct	),seconds
R6791	T21956	T21949	punct	.,B
R6792	T21958	T21959	nsubj	Bars,are
R6793	T21960	T21961	det	the,SEM
R6794	T21961	T21959	attr	SEM,are
R6795	T21962	T21961	nmod	mean,SEM
R6796	T21963	T21961	punct	±,SEM
R6797	T21964	T21961	prep	of,SEM
R6798	T21965	T21966	quantmod	7,28
R6799	T21966	T21968	nummod	28,mice
R6800	T21967	T21966	punct	–,28
R6801	T21968	T21964	pobj	mice,of
R6802	T21969	T21959	punct	.,are
R6803	T21971	T21972	amod	Statistical,differences
R6804	T21972	T21973	nsubjpass	differences,determined
R6805	T21974	T21972	prep	between,differences
R6806	T21975	T21976	compound	B6,mice
R6807	T21976	T21974	pobj	mice,between
R6808	T21977	T21976	cc	and,mice
R6809	T21978	T21976	conj	CSS,mice
R6810	T21979	T21973	auxpass	were,determined
R6811	T21980	T21973	prep	with,determined
R6812	T21981	T21982	det	a,test
R6813	T21982	T21980	pobj	test,with
R6814	T21983	T21982	compound	t,test
R6815	T21984	T21982	punct	-,test
R6816	T21985	T21973	punct	", ",determined
R6817	T21986	T21973	cc	and,determined
R6818	T21987	T21988	det	a,correction
R6819	T21988	T21990	nsubjpass	correction,made
R6820	T21989	T21988	compound	Bonferroni,correction
R6821	T21990	T21973	conj	made,determined
R6822	T21991	T21990	auxpass	was,made
R6823	T21992	T21993	aux	to,determine
R6824	T21993	T21990	advcl	determine,made
R6825	T21994	T21995	compound	significance,value
R6826	T21995	T21993	dobj	value,determine
R6827	T21996	T21997	punct	(,0.002
R6828	T21997	T21995	parataxis	0.002,value
R6829	T21998	T21997	nsubj	P,0.002
R6830	T21999	T21997	punct	<,0.002
R6831	T22000	T21997	punct	),0.002
R6832	T22001	T21990	punct	.,made
R6833	T22003	T22004	nsubj	Symbols,indicate
R6834	T22005	T22006	det	a,difference
R6835	T22006	T22004	dobj	difference,indicate
R6836	T22007	T22006	amod	significant,difference
R6837	T22008	T22006	prep	between,difference
R6838	T22009	T22010	compound	B6,values
R6839	T22010	T22008	pobj	values,between
R6840	T22011	T22004	punct	.,indicate
R6841	T22013	T22014	punct	*,P
R6842	T22014	T22015	nsubj	P,0.002
R6843	T22016	T22015	punct	<,0.002
R6844	T22017	T22015	punct	.,0.002
R6845	T22254	T22255	nmod	Bleeding,time
R6846	T22256	T22254	cc	and,Bleeding
R6847	T22257	T22254	conj	rebleeding,Bleeding
R6848	T22258	T22255	prep	in,time
R6849	T22259	T22260	det	the,backcrosses
R6850	T22260	T22258	pobj	backcrosses,in
R6851	T22261	T22260	compound	CSS,backcrosses
R6852	T22262	T22255	punct	.,time
R6853	T22264	T22265	compound	Panel,A
R6854	T22265	T22266	nsubjpass	A,tested
R6855	T22267	T22265	punct	: ,A
R6856	T22268	T22269	compound	Bleeding,Time
R6857	T22269	T22265	appos	Time,A
R6858	T22270	T22271	punct	(,seconds
R6859	T22271	T22269	parataxis	seconds,Time
R6860	T22272	T22271	punct	),seconds
R6861	T22273	T22265	cc	and,A
R6862	T22274	T22275	compound	Panel,B
R6863	T22275	T22265	conj	B,A
R6864	T22276	T22275	punct	: ,B
R6865	T22277	T22278	compound	Rebleeding,Time
R6866	T22278	T22275	appos	Time,B
R6867	T22279	T22280	punct	(,seconds
R6868	T22280	T22278	parataxis	seconds,Time
R6869	T22281	T22280	punct	),seconds
R6870	T22282	T22266	auxpass	were,tested
R6871	T22283	T22266	prep	in,tested
R6872	T22284	T22285	amod	heterosomic,mice
R6873	T22285	T22283	pobj	mice,in
R6874	T22286	T22285	punct	", ",mice
R6875	T22287	T22288	punct	(,F1
R6876	T22288	T22285	appos	F1,mice
R6877	T22289	T22288	nmod	B6xCSS,F1
R6878	T22290	T22289	punct	-,B6xCSS
R6879	T22291	T22289	nummod	5,B6xCSS
R6880	T22292	T22288	punct	),F1
R6881	T22293	T22288	punct	(,F1
R6882	T22294	T22288	appos	5F1,F1
R6883	T22295	T22288	punct	),F1
R6884	T22296	T22288	cc	and,F1
R6885	T22297	T22298	punct	(,F1
R6886	T22298	T22288	conj	F1,F1
R6887	T22299	T22298	nmod	B6xCSS,F1
R6888	T22300	T22299	punct	-,B6xCSS
R6889	T22301	T22299	nummod	17,B6xCSS
R6890	T22302	T22298	punct	),F1
R6891	T22303	T22298	punct	(,F1
R6892	T22304	T22298	appos	17F1,F1
R6893	T22305	T22285	punct	),mice
R6894	T22306	T22285	cc	and,mice
R6895	T22307	T22308	advmod	doubly,heterosomic
R6896	T22308	T22309	amod	heterosomic,mice
R6897	T22309	T22285	conj	mice,mice
R6898	T22310	T22309	prep	for,mice
R6899	T22311	T22312	nmod	chromosomes,5
R6900	T22312	T22310	pobj	5,for
R6901	T22313	T22312	cc	and,5
R6902	T22314	T22312	conj	17,5
R6903	T22315	T22309	punct	(,mice
R6904	T22316	T22317	nummod	5,17
R6905	T22317	T22309	appos	17,mice
R6906	T22318	T22317	punct	×,17
R6907	T22319	T22266	punct	),tested
R6908	T22320	T22266	punct	.,tested
R6909	T22322	T22323	nsubj	Bars,are
R6910	T22324	T22325	det	the,SEM
R6911	T22325	T22323	attr	SEM,are
R6912	T22326	T22325	nmod	mean,SEM
R6913	T22327	T22325	punct	±,SEM
R6914	T22328	T22325	prep	of,SEM
R6915	T22329	T22330	quantmod	5,8
R6916	T22330	T22333	nummod	8,mice
R6917	T22331	T22330	punct	–,8
R6918	T22332	T22330	compound	2,8
R6919	T22333	T22328	pobj	mice,of
R6920	T22334	T22323	punct	.,are
R6921	T22336	T22337	amod	Statistical,differences
R6922	T22337	T22338	nsubjpass	differences,determined
R6923	T22339	T22337	prep	between,differences
R6924	T22340	T22341	compound	B6,mice
R6925	T22341	T22339	pobj	mice,between
R6926	T22342	T22341	cc	and,mice
R6927	T22343	T22344	det	the,CSS
R6928	T22344	T22341	conj	CSS,mice
R6929	T22345	T22338	auxpass	were,determined
R6930	T22346	T22338	prep	with,determined
R6931	T22347	T22348	det	a,test
R6932	T22348	T22346	pobj	test,with
R6933	T22349	T22348	compound	t,test
R6934	T22350	T22348	punct	-,test
R6935	T22351	T22338	punct	", ",determined
R6936	T22352	T22338	cc	and,determined
R6937	T22353	T22354	det	a,correction
R6938	T22354	T22356	nsubjpass	correction,made
R6939	T22355	T22354	compound	Bonferroni,correction
R6940	T22356	T22338	conj	made,determined
R6941	T22357	T22356	auxpass	was,made
R6942	T22358	T22359	aux	to,determine
R6943	T22359	T22356	advcl	determine,made
R6944	T22360	T22361	compound	significance,value
R6945	T22361	T22359	dobj	value,determine
R6946	T22362	T22363	punct	(,0.01
R6947	T22363	T22361	parataxis	0.01,value
R6948	T22364	T22363	nsubj	P,0.01
R6949	T22365	T22363	punct	<,0.01
R6950	T22366	T22363	punct	),0.01
R6951	T22367	T22356	punct	.,made
R6952	T22369	T22370	nsubj	Symbols,indicate
R6953	T22371	T22372	det	a,difference
R6954	T22372	T22370	dobj	difference,indicate
R6955	T22373	T22372	amod	significant,difference
R6956	T22374	T22372	prep	between,difference
R6957	T22375	T22376	compound	B6,values
R6958	T22376	T22374	pobj	values,between
R6959	T22377	T22370	punct	.,indicate
R6960	T22379	T22380	punct	*,0.01
R6961	T22381	T22380	nsubj	P,0.01
R6962	T22382	T22380	punct	<,0.01
R6963	T22383	T22380	punct	.,0.01
R6964	T22648	T22647	punct	-,PAI
R6965	T22649	T22647	nummod	1,PAI
R6966	T22650	T22647	prep	in,PAI
R6967	T22651	T22652	det	the,backcrosses
R6968	T22652	T22650	pobj	backcrosses,in
R6969	T22653	T22652	compound	CSS,backcrosses
R6970	T22654	T22647	punct	.,PAI
R6971	T22656	T22657	compound	Panel,A
R6972	T22657	T22658	nsubjpass	A,tested
R6973	T22659	T22657	punct	: ,A
R6974	T22660	T22661	nmod	Plasma,antigen
R6975	T22661	T22657	appos	antigen,A
R6976	T22662	T22661	nmod	PAI,antigen
R6977	T22663	T22662	punct	-,PAI
R6978	T22664	T22662	nummod	1,PAI
R6979	T22665	T22666	punct	(,ng
R6980	T22666	T22661	parataxis	ng,antigen
R6981	T22667	T22668	punct	/,mL
R6982	T22668	T22666	prep	mL,ng
R6983	T22669	T22666	punct	),ng
R6984	T22670	T22657	cc	and,A
R6985	T22671	T22672	compound	Panel,B
R6986	T22672	T22657	conj	B,A
R6987	T22673	T22672	punct	: ,B
R6988	T22674	T22675	nmod	Plasma,activity
R6989	T22675	T22672	appos	activity,B
R6990	T22676	T22675	nmod	PAI,activity
R6991	T22677	T22676	punct	-,PAI
R6992	T22678	T22676	nummod	1,PAI
R6993	T22679	T22680	punct	(,U
R6994	T22680	T22675	parataxis	U,activity
R6995	T22681	T22682	punct	/,mL
R6996	T22682	T22680	prep	mL,U
R6997	T22683	T22680	punct	),U
R6998	T22684	T22658	auxpass	were,tested
R6999	T22685	T22658	prep	in,tested
R7000	T22686	T22687	amod	heterosomic,mice
R7001	T22687	T22685	pobj	mice,in
R7002	T22688	T22687	punct	", ",mice
R7003	T22689	T22690	punct	(,F1
R7004	T22690	T22687	appos	F1,mice
R7005	T22691	T22690	nmod	B6xCSS,F1
R7006	T22692	T22691	punct	-,B6xCSS
R7007	T22693	T22691	nummod	5,B6xCSS
R7008	T22694	T22690	punct	),F1
R7009	T22695	T22690	punct	(,F1
R7010	T22696	T22690	appos	5F1,F1
R7011	T22697	T22690	punct	),F1
R7012	T22698	T22690	cc	and,F1
R7013	T22699	T22700	punct	(,F1
R7014	T22700	T22690	conj	F1,F1
R7015	T22701	T22700	nmod	B6xCSS,F1
R7016	T22702	T22701	punct	-,B6xCSS
R7017	T22703	T22701	nummod	17,B6xCSS
R7018	T22704	T22700	punct	),F1
R7019	T22705	T22700	punct	(,F1
R7020	T22706	T22700	appos	17F1,F1
R7021	T22707	T22687	punct	),mice
R7022	T22708	T22687	cc	and,mice
R7023	T22709	T22710	advmod	doubly,heterosomic
R7024	T22710	T22711	amod	heterosomic,mice
R7025	T22711	T22687	conj	mice,mice
R7026	T22712	T22711	prep	for,mice
R7027	T22713	T22714	nmod	chromosomes,5
R7028	T22714	T22712	pobj	5,for
R7029	T22715	T22714	cc	and,5
R7030	T22716	T22714	conj	17,5
R7031	T22717	T22711	punct	(,mice
R7032	T22718	T22719	nummod	5,17
R7033	T22719	T22711	appos	17,mice
R7034	T22720	T22719	punct	×,17
R7035	T22721	T22658	punct	),tested
R7036	T22722	T22658	punct	.,tested
R7037	T22724	T22725	nsubj	Bars,are
R7038	T22726	T22727	det	the,SEM
R7039	T22727	T22725	attr	SEM,are
R7040	T22728	T22727	nmod	mean,SEM
R7041	T22729	T22727	punct	±,SEM
R7042	T22730	T22727	prep	of,SEM
R7043	T22731	T22732	quantmod	5,18
R7044	T22732	T22734	nummod	18,mice
R7045	T22733	T22732	punct	–,18
R7046	T22734	T22730	pobj	mice,of
R7047	T22735	T22725	punct	.,are
R7048	T22737	T22738	amod	Statistical,differences
R7049	T22738	T22739	nsubjpass	differences,determined
R7050	T22740	T22738	prep	between,differences
R7051	T22741	T22742	compound	B6,mice
R7052	T22742	T22740	pobj	mice,between
R7053	T22743	T22742	cc	and,mice
R7054	T22744	T22742	conj	CSS,mice
R7055	T22745	T22739	auxpass	were,determined
R7056	T22746	T22739	prep	with,determined
R7057	T22747	T22748	det	a,test
R7058	T22748	T22746	pobj	test,with
R7059	T22749	T22748	compound	t,test
R7060	T22750	T22748	punct	-,test
R7061	T22751	T22739	punct	", ",determined
R7062	T22752	T22739	cc	and,determined
R7063	T22753	T22754	det	a,correction
R7064	T22754	T22756	nsubjpass	correction,made
R7065	T22755	T22754	compound	Bonferroni,correction
R7066	T22756	T22739	conj	made,determined
R7067	T22757	T22756	auxpass	was,made
R7068	T22758	T22759	aux	to,determine
R7069	T22759	T22756	advcl	determine,made
R7070	T22760	T22761	compound	significance,value
R7071	T22761	T22759	dobj	value,determine
R7072	T22762	T22763	punct	(,0.01
R7073	T22763	T22759	parataxis	0.01,determine
R7074	T22764	T22763	nsubj	P,0.01
R7075	T22765	T22763	punct	<,0.01
R7076	T22766	T22763	punct	),0.01
R7077	T22767	T22756	punct	.,made
R7078	T22769	T22770	nsubj	Symbols,indicate
R7079	T22771	T22772	det	a,difference
R7080	T22772	T22770	dobj	difference,indicate
R7081	T22773	T22772	amod	significant,difference
R7082	T22774	T22772	prep	between,difference
R7083	T22775	T22776	compound	B6,values
R7084	T22776	T22774	pobj	values,between
R7085	T22777	T22770	punct	.,indicate
R7086	T22779	T22780	punct	*,P
R7087	T22780	T22781	nsubj	P,0.01
R7088	T22782	T22781	punct	<,0.01
R7089	T22783	T22781	punct	.,0.01
R7090	T22995	T22996	amod	Arterial,occlusion
R7091	T22996	T22997	compound	occlusion,time
R7092	T22998	T22997	prep	in,time
R7093	T22999	T23000	det	the,backcrosses
R7094	T23000	T22998	pobj	backcrosses,in
R7095	T23001	T23000	compound	CSS,backcrosses
R7096	T23002	T22997	punct	.,time
R7097	T23004	T23005	compound	Occlusion,time
R7098	T23005	T23006	nsubjpass	time,determined
R7099	T23007	T23006	auxpass	was,determined
R7100	T23008	T23006	prep	in,determined
R7101	T23009	T23010	amod	heterosomic,mice
R7102	T23010	T23008	pobj	mice,in
R7103	T23011	T23010	punct	", ",mice
R7104	T23012	T23010	punct	(,mice
R7105	T23013	T23014	nmod	B6xCSS,F1
R7106	T23014	T23010	appos	F1,mice
R7107	T23015	T23013	punct	-,B6xCSS
R7108	T23016	T23013	nummod	5,B6xCSS
R7109	T23017	T23014	punct	),F1
R7110	T23018	T23014	punct	(,F1
R7111	T23019	T23014	appos	5F1,F1
R7112	T23020	T23014	punct	),F1
R7113	T23021	T23014	cc	and,F1
R7114	T23022	T23023	punct	(,F1
R7115	T23023	T23014	conj	F1,F1
R7116	T23024	T23023	nmod	B6xCSS,F1
R7117	T23025	T23024	punct	-,B6xCSS
R7118	T23026	T23024	nummod	17,B6xCSS
R7119	T23027	T23023	punct	),F1
R7120	T23028	T23023	punct	(,F1
R7121	T23029	T23023	appos	17F1,F1
R7122	T23030	T23010	punct	),mice
R7123	T23031	T23010	punct	", ",mice
R7124	T23032	T23010	cc	and,mice
R7125	T23033	T23034	advmod	doubly,heterosomic
R7126	T23034	T23035	amod	heterosomic,mice
R7127	T23035	T23010	conj	mice,mice
R7128	T23036	T23035	prep	for,mice
R7129	T23037	T23038	nmod	chromosomes,5
R7130	T23038	T23036	pobj	5,for
R7131	T23039	T23038	cc	and,5
R7132	T23040	T23038	conj	17,5
R7133	T23041	T23035	punct	(,mice
R7134	T23042	T23043	nummod	5,17
R7135	T23043	T23035	appos	17,mice
R7136	T23044	T23043	punct	×,17
R7137	T23045	T23006	punct	),determined
R7138	T23046	T23006	punct	.,determined
R7139	T23048	T23049	nsubj	Bars,are
R7140	T23050	T23051	det	the,SEM
R7141	T23051	T23049	attr	SEM,are
R7142	T23052	T23051	nmod	mean,SEM
R7143	T23053	T23051	punct	±,SEM
R7144	T23054	T23051	prep	of,SEM
R7145	T23055	T23056	quantmod	5,18
R7146	T23056	T23058	nummod	18,mice
R7147	T23057	T23056	punct	–,18
R7148	T23058	T23054	pobj	mice,of
R7149	T23059	T23049	punct	.,are
R7150	T23061	T23062	amod	Statistical,differences
R7151	T23062	T23063	nsubjpass	differences,determined
R7152	T23064	T23062	prep	between,differences
R7153	T23065	T23066	compound	B6,mice
R7154	T23066	T23064	pobj	mice,between
R7155	T23067	T23066	cc	and,mice
R7156	T23068	T23066	conj	CSS,mice
R7157	T23069	T23063	auxpass	were,determined
R7158	T23070	T23063	prep	with,determined
R7159	T23071	T23072	det	a,test
R7160	T23072	T23070	pobj	test,with
R7161	T23073	T23072	compound	t,test
R7162	T23074	T23072	punct	-,test
R7163	T23075	T23063	punct	", ",determined
R7164	T23076	T23063	cc	and,determined
R7165	T23077	T23078	det	a,correction
R7166	T23078	T23080	nsubjpass	correction,made
R7167	T23079	T23078	compound	Bonferroni,correction
R7168	T23080	T23063	conj	made,determined
R7169	T23081	T23080	auxpass	was,made
R7170	T23082	T23083	aux	to,determine
R7171	T23083	T23080	advcl	determine,made
R7172	T23084	T23085	compound	significance,value
R7173	T23085	T23083	dobj	value,determine
R7174	T23086	T23087	punct	(,0.02
R7175	T23087	T23085	parataxis	0.02,value
R7176	T23088	T23087	nsubj	P,0.02
R7177	T23089	T23087	punct	<,0.02
R7178	T23090	T23087	punct	),0.02
R7179	T23091	T23080	punct	.,made
R7180	T23093	T23094	nsubj	Symbols,indicate
R7181	T23095	T23096	det	a,difference
R7182	T23096	T23094	dobj	difference,indicate
R7183	T23097	T23096	amod	significant,difference
R7184	T23098	T23096	prep	between,difference
R7185	T23099	T23100	compound	B6,values
R7186	T23100	T23098	pobj	values,between
R7187	T23101	T23094	punct	.,indicate
R7188	T23103	T23104	punct	*,P
R7189	T23104	T23105	nsubj	P,0.0001
R7190	T23106	T23105	punct	<,0.0001
R7191	T23107	T23105	punct	.,0.0001
R7192	T23141	T23142	nmod	Coagulation,Parameters
R7193	T23143	T23141	cc	and,Coagulation
R7194	T23144	T23141	conj	Plasminogen,Coagulation
R7195	T23145	T23142	compound	System,Parameters
R7196	T23146	T23142	prep	in,Parameters
R7197	T23147	T23148	nmod	B6,strains
R7198	T23148	T23146	pobj	strains,in
R7199	T23149	T23147	cc	and,B6
R7200	T23150	T23151	compound	A,J
R7201	T23151	T23147	conj	J,B6
R7202	T23152	T23151	punct	/,J
R7203	T23153	T23148	amod	inbred,strains
R7204	T23154	T23148	compound	mouse,strains
R3899	T12970	T12965	cc	and,%
R3900	T12971	T12972	compound	CSS,A17
R3901	T12972	T12974	dep	A17,%
R3902	T12973	T12972	punct	-,A17
R3903	T12974	T12965	conj	%,%
R3904	T12975	T12974	punct	–,%
R3905	T12976	T12974	nummod	46,%
R3906	T12977	T12937	punct	.,stopped
R3907	T12979	T12980	det	The,percentage
R3908	T12980	T12981	nsubj	percentage,was
R3909	T12982	T12980	prep	of,percentage
R3910	T12983	T12984	compound	B6,mice
R3911	T12984	T12982	pobj	mice,of
R3912	T12985	T12980	prep	with,percentage
R3913	T12986	T12987	det	a,time
R3914	T12987	T12985	pobj	time,with
R3915	T12988	T12987	compound	rebleeding,time
R3916	T12989	T12987	prep	of,time
R3917	T12990	T12991	nummod	600,sec
R3918	T12991	T12989	pobj	sec,of
R3919	T12992	T12993	nummod	7,%
R3920	T12993	T12981	attr	%,was
R3921	T12994	T12981	cc	and,was
R3922	T12995	T12996	prep	for,was
R3923	T12996	T12981	conj	was,was
R3924	T12997	T12998	det	the,mice
R3925	T12998	T12995	pobj	mice,for
R3926	T12999	T13000	compound	A,J
R3927	T13000	T12998	compound	J,mice
R3928	T13001	T13000	punct	/,J
R3929	T13002	T13003	det	the,percentage
R3930	T13003	T12996	nsubj	percentage,was
R3931	T13004	T13005	nummod	85,%
R3932	T13005	T12996	attr	%,was
R3933	T13006	T12996	punct	.,was
R3934	T13008	T13009	compound	Rebleeding,time
R3935	T13009	T13010	nsubjpass	time,compared
R3936	T13011	T13009	prep	in,time
R3937	T13012	T13013	det	the,strains
R3938	T13013	T13011	pobj	strains,in
R3939	T13014	T13013	compound	parent,strains
R3940	T13015	T13013	cc	and,strains
R3941	T13016	T13013	conj	CSS,strains
R3942	T13017	T13010	auxpass	were,compared
R3943	T13018	T13010	prep	to,compared
R3944	T13019	T13018	pobj	values,to
R3945	T13020	T13019	prep	from,values
R3946	T13021	T13022	det	the,progeny
R3947	T13022	T13020	pobj	progeny,from
R3948	T13023	T13022	prep	of,progeny
R3949	T13024	T13023	pobj	mice,of
R3950	T13025	T13026	dep	that,crossed
R3951	T13026	T13024	relcl	crossed,mice
R3952	T13027	T13026	auxpass	were,crossed
R3953	T13028	T13026	prep	with,crossed
R3954	T13029	T13030	compound	B6,mice
R3955	T13030	T13028	pobj	mice,with
R3956	T13031	T13032	aux	to,produce
R3957	T13032	T13026	advcl	produce,crossed
R3958	T13033	T13034	amod	heterosomic,mice
R3959	T13034	T13032	dobj	mice,produce
R3960	T13035	T13032	prep	for,produce
R3961	T13036	T13037	det	the,strains
R3962	T13037	T13035	pobj	strains,for
R3963	T13038	T13039	nmod	CSS,F1
R3964	T13039	T13037	nmod	F1,strains
R2806	T9605	T9604	prep	to,compared
R2807	T9606	T9607	compound	WT,littermates
R2808	T9607	T9605	pobj	littermates,to
R2809	T9608	T9607	compound	mice,littermates
R2810	T9609	T9585	punct	.,increased
R2811	T9611	T9612	compound	Bleeding,time
R2812	T9612	T9613	nsubj	time,was
R2813	T9614	T9613	neg	not,was
R2814	T9615	T9613	acomp	different,was
R2815	T9616	T9613	prep	in,was
R2816	T9617	T9618	nmod	PAI,mice
R2817	T9618	T9616	pobj	mice,in
R2818	T9619	T9617	punct	-,PAI
R2819	T9620	T9617	nummod	1,PAI
R2820	T9621	T9617	punct	-,PAI
R2871	T9675	T9676	compound	Rebleeding,time
R2872	T9676	T9677	nsubjpass	time,measured
R2873	T9678	T9676	punct	", ",time
R2874	T9679	T9680	det	an,indicator
R2875	T9680	T9676	appos	indicator,time
R2876	T9681	T9680	prep	of,indicator
R2877	T9682	T9683	compound	thrombus,stability
R2878	T9683	T9681	pobj	stability,of
R2879	T9684	T9677	punct	", ",measured
R2880	T9685	T9677	auxpass	was,measured
R2881	T9686	T9677	prep	as,measured
R2882	T9687	T9688	det	the,time
R2883	T9688	T9686	pobj	time,as
R2884	T9689	T9688	prep	between,time
R2885	T9690	T9691	det	the,cessation
R2886	T9691	T9689	pobj	cessation,between
R2887	T9692	T9691	prep	of,cessation
R2888	T9693	T9692	pobj	bleeding,of
R2889	T9694	T9691	cc	and,cessation
R2890	T9695	T9696	det	the,start
R2891	T9696	T9691	conj	start,cessation
R2892	T9697	T9696	prep	of,start
R2893	T9698	T9699	det	the,bleeding
R2894	T9699	T9697	pobj	bleeding,of
R2895	T9700	T9699	amod	second,bleeding
R2896	T9701	T9702	punct	(,2B
R2897	T9702	T9677	parataxis	2B,measured
R2898	T9703	T9702	compound	Figure,2B
R2899	T9704	T9702	punct	),2B
R2900	T9705	T9677	punct	.,measured
R2901	T9707	T9708	compound	Rebleeding,times
R2902	T9708	T9709	nsubj	times,were
R2903	T9710	T9711	advmod	significantly,higher
R2904	T9711	T9709	acomp	higher,were
R10	T1024	T1023	amod	fatal,consequence
R11	T1025	T1024	cc	and,fatal
R12	T1026	T1024	conj	disabling,fatal
R19	T1033	T1032	amod	leading,cause
R30	T1045	T1044	amod	inbred,strains
R31	T1046	T1044	compound	mouse,strains
R35	T1051	T1050	punct	/,6J
R39	T1055	T1054	punct	/,J
R60	T1078	T1079	det	these,backgrounds
R85	T1105	T1104	nummod	two,strains
R86	T1106	T1104	amod	inbred,strains
R91	T1111	T1110	amod	phenotypic,response
R95	T1115	T1114	punct	/,J
R100	T1120	T1121	compound	C57BL,6J
R106	T1129	T1128	punct	/,J
R108	T1131	T1128	cc	and,J
R109	T1132	T1133	compound	C57Bl,6J
R126	T1152	T1151	amod	carotid,artery
R132	T1158	T1157	amod	exposed,carotid
R142	T1168	T1169	det	the,vessel
R143	T1169	T1167	nsubj	vessel,occluded
R147	T1174	T1172	cc	and,Bleeding
R148	T1175	T1172	conj	rebleeding,Bleeding
R171	T1200	T1199	punct	-,one
R173	T1202	T1201	compound	chromosome,strains
R174	T1203	T1201	compound	substitution,strains
R178	T1208	T1207	punct	/,J
R183	T1213	T1214	compound	C57BL,6J
R193	T1223	T1224	compound	tail,bleeding
R194	T1224	T1222	compound	bleeding,assay
R204	T1238	T1239	compound	A,J
R211	T1245	T1244	punct	/,6J
R221	T1257	T1256	nummod	two,strains
R227	T1263	T1262	auxpass	was,increased
R228	T1264	T1262	advmod	markedly,increased
R232	T1268	T1269	compound	A,J
R239	T1275	T1274	punct	/,6J
R258	T1296	T1295	punct	/,J
R262	T1300	T1299	punct	/,6J
R267	T1306	T1305	compound	chromosome,strains
R268	T1307	T1305	compound	substitution,strains
R272	T1312	T1311	punct	-,Chr5A
R274	T1314	T1313	punct	/,J
R278	T1318	T1317	punct	-,Chr11A
R280	T1320	T1319	punct	/,J
R285	T1325	T1324	punct	-,Chr17A
R287	T1327	T1326	punct	/,J
R293	T1333	T1332	compound	rebleeding,time
R301	T1341	T1340	punct	/,J
R317	T1359	T1358	punct	/,6J
R323	T1365	T1366	det	these,strains
R328	T1370	T1366	punct	", ",strains
R329	T1371	T1372	compound	B6,Chr5A
R334	T1376	T1374	cc	and,J
R335	T1377	T1378	compound	B6,Chr17A
R340	T1382	T1364	punct	", ",crossed
R341	T1383	T1364	auxpass	were,crossed
R343	T1385	T1384	punct	", ",restored
R344	T1386	T1387	det	the,phenotype
R347	T1389	T1387	compound	J,phenotype
R349	T1391	T1384	auxpass	was,restored
R353	T1395	T1396	advmod	doubly,heterosomic
R354	T1396	T1394	amod	heterosomic,progeny
R360	T1406	T1405	nsubj	susceptibility,is
R361	T1407	T1406	prep	to,susceptibility
R362	T1408	T1409	amod	arterial,thrombosis
R363	T1409	T1407	pobj	thrombosis,to
R364	T1410	T1409	cc	and,thrombosis
R365	T1411	T1409	conj	haemostasis,thrombosis
R371	T1417	T1415	punct	/,C57BL
R372	T1418	T1415	cc	and,C57BL
R373	T1419	T1415	conj	A,C57BL
R374	T1420	T1419	punct	/,A
R379	T1426	T1427	compound	A,J
R382	T1429	T1425	compound	chromosome,strains
R383	T1430	T1425	compound	substitution,strains
R393	T1441	T1440	punct	/,J
R399	T1447	T1448	compound	C57Bl,6J
R403	T1451	T1450	aux	could,modify
R406	T1454	T1455	compound	A,J
R414	T1462	T1460	prep	of,combination
R415	T1463	T1464	nummod	two,QTL
R418	T1466	T1464	compound	J,QTL
R420	T1468	T1461	aux	could,restore
R426	T1475	T1474	amod	diverse,backgrounds
R427	T1476	T1474	amod	genetic,backgrounds
R440	T1490	T1491	compound	tail,bleeding
R441	T1491	T1489	compound	bleeding,assay
R449	T1499	T1498	amod	genetic,determinants
R499	T3178	T3176	pobj	plaques,on
R502	T3181	T3175	attr	event,is
R518	T3197	T3195	pobj	infarction,to
R602	T3287	T3285	pobj	decade,in
R662	T3351	T3332	conj	contributes,influences
R786	T3511	T3510	punct	", ",coagulation
R790	T3512	T3510	cc	and,coagulation
R795	T3513	T3514	amod	fibrinolytic,functions
R798	T3514	T3510	conj	functions,coagulation
R802	T3515	T3498	punct	.,requires
R805	T3517	T3518	nsubj	Interactions,occur
R811	T3519	T3517	prep	among,Interactions
R816	T3520	T3521	det	these,pathways
R819	T3521	T3519	pobj	pathways,among
R823	T3522	T3518	aux	may,occur
R824	T3523	T3518	cc	and,occur
R825	T3524	T3525	amod	additional,factors
R827	T3525	T3526	nsubj	factors,modulate
R830	T3526	T3518	conj	modulate,occur
R833	T3527	T3526	aux	may,modulate
R836	T3528	T3529	det	these,processes
R840	T3529	T3526	dobj	processes,modulate
R844	T3530	T3526	punct	.,modulate
R848	T3532	T3533	nsubjpass	Identification,identified
R853	T3534	T3532	prep	of,Identification
R857	T3535	T3536	amod	novel,modulators
R862	T3536	T3534	pobj	modulators,of
R865	T3537	T3536	cc	and,modulators
R870	T3538	T3536	conj	factors,modulators
R877	T3539	T3536	prep	of,modulators
R880	T3540	T3541	det	these,pathways
R882	T3541	T3539	pobj	pathways,of
R887	T3542	T3533	aux	can,identified
R826	T3571	T3572	nsubjpass	panel,generated
R828	T3573	T3571	prep	of,panel
R829	T3574	T3575	compound	chromosome,strains
R831	T3575	T3573	pobj	strains,of
R832	T3576	T3575	compound	substitution,strains
R834	T3577	T3575	punct	(,strains
R835	T3578	T3575	appos	CSS,strains
R837	T3579	T3572	punct	),generated
R838	T3580	T3572	auxpass	was,generated
R839	T3581	T3582	punct	[,11
R841	T3582	T3572	parataxis	11,generated
R842	T3583	T3582	punct	],11
R843	T3584	T3572	agent	by,generated
R845	T3585	T3586	det	a,program
R846	T3586	T3584	pobj	program,by
R847	T3587	T3586	punct	"""",program
R849	T3588	T3589	npadvmod	marker,assisted
R850	T3589	T3586	amod	assisted,program
R851	T3590	T3589	punct	-,assisted
R852	T3591	T3586	punct	"""",program
R6141	T20135	T20134	prep	in,time
R6146	T20136	T20137	det	a,assay
R6148	T20137	T20135	pobj	assay,in
R6150	T20138	T20139	compound	tail,bleeding
R6153	T20139	T20137	compound	bleeding,assay
R6156	T20140	T20134	punct	", ",time
R6159	T20141	T20142	compound	plasminogen,function
R6162	T20142	T20134	conj	function,time
R6165	T20143	T20142	punct	", ",function
R6166	T20144	T20142	cc	and,function
R6168	T20145	T20146	nmod	tissue,deposition
R6171	T20146	T20142	conj	deposition,function
R6175	T20147	T20145	cc	and,tissue
R6178	T20148	T20145	conj	vessel,tissue
R6183	T20149	T20146	compound	collagen,deposition
R6190	T20150	T20102	punct	.,reports
R6194	T20152	T20153	nummod	Three,chromosomes
R6199	T20153	T20154	nsubjpass	chromosomes,identified
R6203	T20155	T20153	prep	from,chromosomes
R6208	T20156	T20157	compound	A,J

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id	Subject	Object	Predicate	Lexical cue
T938	0-7	SO_EXT:0000704	denotes	Genetic
T939	30-38	GO_EXT:reaction_or_response	denotes	response
T941	57-67	GO:0007596	denotes	thrombosis
T942	89-99	GO:0007596	denotes	Thrombosis
T943	107-112	GO_EXT:fatality_or_lethality	denotes	fatal
T944	142-156	UBERON:0004535	denotes	cardiovascular
T945	245-250	NCBITaxon:10088	denotes	mouse
T946	353-359	UBERON:0000055	denotes	vessel
T947	413-420	SO_EXT:0000704	denotes	genetic
T948	461-469	GO:0065007	denotes	regulate
T949	470-480	GO:0007596	denotes	thrombosis
T950	485-495	GO:0007599	denotes	hemostasis
T951	541-551	GO:0007596	denotes	thrombosis
T952	556-566	GO:0007599	denotes	hemostasis
T953	624-632	GO_EXT:reaction_or_response	denotes	response
T954	640-651	GO_SO_EXT:chromosome	denotes	chromosomes
T955	706-710	NCBITaxon:10088	denotes	mice
T956	745-755	GO:0007596	denotes	thrombosis
T957	760-770	GO:0007599	denotes	hemostasis
T958	774-782	UBERON:0010210	denotes	thrombus
T959	802-816	UBERON:0005396	denotes	carotid artery
T960	847-854	UBERON:0005396	denotes	carotid
T961	858-873	CHEBI:30808	denotes	ferric chloride
T962	878-883	UBERON:0000178	denotes	blood
T963	908-914	UBERON:0000055	denotes	vessel
T964	981-991	GO:0007596	denotes	thrombosis
T965	996-1006	GO:0007599	denotes	hemostasis
T966	1043-1047	UBERON:0002415	denotes	tail
T967	1068-1074	CHEBI_EXT:saline_solution	denotes	saline
T968	1087-1097	GO_SO_EXT:chromosome	denotes	chromosome
T969	1098-1110	SO_EXT:sequence_substitution_entity_or_process	denotes	substitution
T970	1124-1135	GO_SO_EXT:chromosome	denotes	chromosomes
T971	1180-1188	GO_EXT:reaction_or_response	denotes	response
T972	1196-1200	UBERON:0002415	denotes	tail
T973	1226-1234	UBERON:0010210	denotes	Thrombus
T974	1226-1244	GO:0007599	denotes	Thrombus occlusion
T975	1284-1288	NCBITaxon:10088	denotes	mice
T976	1310-1314	NCBITaxon:10088	denotes	mice
T977	1316-1320	UBERON:0002415	denotes	Tail
T978	1421-1425	NCBITaxon:10088	denotes	mice
T979	1447-1451	NCBITaxon:10088	denotes	mice
T980	1453-1464	GO:0050817	denotes	Coagulation
T981	1475-1479	UBERON:0002415	denotes	tail
T982	1509-1513	UBERON:0002415	denotes	tail
T983	1514-1522	CHEBI_PR_EXT:collagen	denotes	collagen
T984	1563-1567	NCBITaxon:10088	denotes	mice
T985	1575-1585	GO_SO_EXT:chromosome	denotes	chromosome
T986	1586-1598	SO_EXT:sequence_substitution_entity_or_process	denotes	substitution
T987	1725-1729	NCBITaxon:10088	denotes	mice
T988	1731-1735	NCBITaxon:10088	denotes	Mice
T989	1752-1763	GO_SO_EXT:chromosome	denotes	chromosomes
T990	1813-1817	NCBITaxon:10088	denotes	mice
T991	1838-1848	GO_SO_EXT:chromosome	denotes	chromosome
T992	1849-1861	SO_EXT:sequence_substitution_entity_or_process	denotes	substitution
T993	2039-2047	UBERON:0001637	denotes	arterial
T994	2048-2058	GO:0007596	denotes	thrombosis
T995	2063-2074	GO:0007599	denotes	haemostasis
T996	2116-2120	NCBITaxon:10088	denotes	mice
T997	2132-2142	GO_SO_EXT:chromosome	denotes	chromosome
T998	2143-2155	SO_EXT:sequence_substitution_entity_or_process	denotes	substitution
T999	2325-2328	SO_EXT:0000771	denotes	QTL
T1000	2370-2377	SO_EXT:0000704	denotes	genetic
T3029	2779-2784	NCBITaxon:9606	denotes	human
T3030	2798-2806	UBERON:0010210	denotes	Thrombus
T3031	2798-2816	GO:0007596	denotes	Thrombus formation
T3032	2970-2980	UBERON:0002349	denotes	myocardial
T3033	3023-3031	UBERON:0001637	denotes	arterial
T3034	3043-3051	UBERON:0001637	denotes	Arterial
T3035	3056-3062	UBERON:0001638	denotes	venous
T3036	3063-3073	GO:0007596	denotes	thrombosis
T3037	3086-3095	GO_EXT:reaction_or_response	denotes	responses
T3038	3127-3134	SO_EXT:0000704	denotes	genetic
T3039	3168-3181	SO_EXT:polymorphism	denotes	Polymorphisms
T3040	3186-3195	SO_EXT:sequence_alteration_entity_or_process	denotes	mutations
T3041	3199-3210	GO:0050817	denotes	coagulation
T3042	3220-3232	GO:0042730	denotes	fibrinolytic
T3043	3242-3250	CL:0000233	denotes	platelet
T3044	3251-3258	GO:0009986	denotes	surface
T3045	3259-3268	GO_EXT:0004872	denotes	receptors
T3046	3270-3295	CHEBI:12071	denotes	methylenetetrahydrofalate
T3047	3270-3305	GO_PR_EXT:methylenetetrahydrofolate_reductase	denotes	methylenetetrahydrofalate reductase
T3048	3307-3318	UBERON:0001986	denotes	endothelial
T3049	3307-3340	PR_EXT:000011328	denotes	endothelial nitric oxide synthase
T3050	3319-3331	CHEBI:16480	denotes	nitric oxide
T3051	3319-3340	GO_EXT:0004517	denotes	nitric oxide synthase
T3052	3346-3357	CHEBI_GO_EXT:antioxidant	denotes	antioxidant
T3053	3350-3357	CHEBI_MOP_EXT:oxidising_agent_or_oxidation	denotes	oxidant
T3054	3358-3365	CHEBI_GO_SO_EXT:enzyme	denotes	enzymes
T3055	3390-3397	SO_EXT:0000704	denotes	genetic
T3056	3432-3442	GO:0007596	denotes	thrombosis
T3057	3513-3523	GO:0007596	denotes	thrombosis
T3058	3575-3585	GO:0007596	denotes	thrombosis
T3059	3678-3685	SO_EXT:0000704	denotes	genetic
T3060	3707-3717	GO:0007596	denotes	thrombotic
T3061	3757-3764	SO_EXT:0000704	denotes	genetic
T3062	3803-3812	CHEBI:36357	denotes	molecules
T3063	3835-3843	GO:0065007	denotes	regulate
T3064	3844-3852	UBERON:0010210	denotes	thrombus
T3065	3844-3862	GO:0007596	denotes	thrombus formation
T3066	3914-3924	GO:0007596	denotes	thrombotic
T3067	3963-3968	NCBITaxon:10088	denotes	mouse
T3068	4131-4140	GO_EXT:reaction_or_response	denotes	responses
T3069	4268-4276	UBERON:0001637	denotes	arterial
T3070	4369-4375	UBERON:0000055	denotes	vessel
T3071	4462-4472	GO:0007596	denotes	thrombosis
T3072	4491-4495	NCBITaxon:10088	denotes	mice
T3073	4539-4549	GO:0007596	denotes	thrombosis
T3074	4551-4555	UBERON:0010210	denotes	Clot
T3075	4551-4565	GO:0050817	denotes	Clot formation
T3076	4604-4614	GO:0007596	denotes	thrombosis
T3077	4625-4633	CL:0000233	denotes	platelet
T3078	4625-4645	GO:0070527	denotes	platelet aggregation
T3079	4647-4658	GO:0050817	denotes	coagulation
T3080	4664-4676	GO:0042730	denotes	fibrinolytic
T3081	4759-4767	GO:0065007	denotes	modulate
T3082	4809-4819	GO_EXT:regulator	denotes	modulators
T3083	4904-4918	_FRAGMENT	denotes	location(s) on
T3084	4930-4940	GO_SO_EXT:chromosomal_part_or_position_or_region_or_site	denotes	chromosome
T3085	4930-4940	GO_SO_EXT:chromosome	denotes	chromosome
T3086	4944-4968	SO_EXT:0000771	denotes	quantitative trait locus
T3087	4970-4973	SO_EXT:0000771	denotes	QTL
T22253	24140-24144	NCBITaxon:10088	denotes	mice
T22252	24099-24103	NCBITaxon:10088	denotes	mice
T22251	24036-24047	GO_SO_EXT:chromosome	denotes	chromosomes
T22250	24027-24031	NCBITaxon:10088	denotes	mice
T22249	23954-23958	NCBITaxon:10088	denotes	mice
T22646	26400-26404	NCBITaxon:10088	denotes	mice
T22645	26359-26363	NCBITaxon:10088	denotes	mice
T22644	26296-26307	GO_SO_EXT:chromosome	denotes	chromosomes
T22643	26287-26291	NCBITaxon:10088	denotes	mice
T22642	26214-26218	NCBITaxon:10088	denotes	mice
T22641	26165-26170	PR_EXT:000014702	denotes	PAI-1
T22640	26158-26164	UBERON:0001969	denotes	Plasma
T22639	26129-26136	CHEBI_EXT:59132	denotes	antigen
T22638	26123-26128	PR_EXT:000014702	denotes	PAI-1
T22637	26116-26122	UBERON:0001969	denotes	Plasma
T22636	26077-26082	PR_EXT:000014702	denotes	PAI-1
T21928	22810-22814	NCBITaxon:10088	denotes	mice
T21927	22769-22773	NCBITaxon:10088	denotes	mice
T21611	21432-21436	NCBITaxon:10088	denotes	mice
T21610	21357-21365	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T21609	21348-21352	NCBITaxon:10088	denotes	mice
T21608	21308-21313	NCBITaxon:10088	denotes	mouse
T21607	21281-21285	UBERON:0002415	denotes	tail
T21606	21202-21206	UBERON:0002415	denotes	tail
T21605	21178-21187	UBERON_EXT:cartilage_element_or_tissue	denotes	cartilage
T21604	21173-21177	UBERON_EXT:bone_element_or_tissue	denotes	bone
T21603	21141-21149	CHEBI_PR_EXT:collagen	denotes	collagen
T21602	21100-21108	CHEBI_PR_EXT:collagen	denotes	collagen
T21601	21064-21068	NCBITaxon:10088	denotes	mice
T21600	20977-20981	NCBITaxon:10088	denotes	mice
T21599	20955-20960	CHEBI_EXT:eosin	denotes	eosin
T21598	20939-20950	CHEBI:51686	denotes	hematoxylin
T21597	20864-20869	CHEBI_EXT:eosin	denotes	Eosin
T21596	20852-20863	CHEBI:51686	denotes	Hematoxylin
T21595	20787-20792	UBERON:0002415	denotes	Tails
T21594	20777-20785	CHEBI_PR_EXT:collagen	denotes	collagen
T21593	20757-20761	UBERON:0002415	denotes	Tail
T20391	36357-36362	SO_EXT:0000704	denotes	genes
T20390	36323-36328	SO_EXT:0000704	denotes	genes
T20389	36247-36258	GO:0007599	denotes	haemostasis
T20388	36232-36242	GO:0007596	denotes	thrombosis
T20387	36208-36215	SO_EXT:0000704	denotes	genetic
T20386	36174-36178	NCBITaxon:10088	denotes	mice
T20770	14440-14444	NCBITaxon:10088	denotes	mice
T20769	14364-14372	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T20768	14355-14359	NCBITaxon:10088	denotes	mice
T20767	14310-14318	UBERON:0001637	denotes	Arterial
T20766	14295-14299	NCBITaxon:10088	denotes	mice
T20765	14276-14280	NCBITaxon:10088	denotes	mice
T20764	14255-14262	UBERON:0005396	denotes	carotid
T20763	14220-14235	CHEBI:30808	denotes	ferric chloride
T20762	14178-14186	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T20761	14111-14115	NCBITaxon:10088	denotes	mice
T20760	14073-14081	UBERON:0001637	denotes	Arterial
T18466	34136-34139	PR_EXT:000012867	denotes	Plg
T18465	34126-34131	SO_EXT:0000704	denotes	genes
T18464	34082-34086	NCBITaxon:10088	denotes	mice
T18463	33992-34000	CHEBI_PR_EXT:protein	denotes	proteins
T18462	33976-33984	CL_GO_EXT:cell	denotes	cellular
T18460	33959-33967	CHEBI_PR_EXT:collagen	denotes	collagen
T18459	33992-34000	GO:0019538	denotes	proteins
T18458	33945-33958	_FRAGMENT	denotes	metabolism of
T18457	33945-33967	GO:0032963	denotes	metabolism of collagen
T18456	33903-33907	NCBITaxon:10088	denotes	mice
T18455	33887-33891	UBERON:0002415	denotes	tail
T18454	33863-33871	CHEBI_PR_EXT:collagen	denotes	collagen
T18453	33828-33832	UBERON:0002415	denotes	tail
T18452	33764-33768	UBERON:0002415	denotes	tail
T18451	33745-33750	UBERON:0000178	denotes	blood
T18450	33690-33695	UBERON:0000178	denotes	blood
T18449	33667-33671	NCBITaxon:10088	denotes	mice
T18448	33653-33656	CHEBI_PR_EXT:leptin	denotes	Lep
T18447	33642-33643	SO_EXT:sequence_nullness_or_absence	denotes	-
T18446	33640-33641	SO_EXT:sequence_nullness_or_absence	denotes	-
T18445	33637-33640	PR_EXT:000012826	denotes	uPA
T18444	33617-33619	SO_EXT:wild_type_entity_or_quality	denotes	WT
T18443	33585-33590	UBERON:0000178	denotes	blood
T18442	33567-33571	NCBITaxon:10088	denotes	mice
T18441	33488-33492	NCBITaxon:10088	denotes	mice
T18440	33486-33487	SO_EXT:sequence_nullness_or_absence	denotes	-
T18439	33484-33485	SO_EXT:sequence_nullness_or_absence	denotes	-
T18438	33481-33484	PR_EXT:000012867	denotes	Plg
T18437	33446-33451	UBERON:0000178	denotes	Blood
T18436	33440-33444	NCBITaxon:10088	denotes	mice
T18435	33389-33394	UBERON:0000178	denotes	blood
T18434	33353-33357	NCBITaxon:10088	denotes	mice
T18433	33259-33263	UBERON:0002415	denotes	tail
T18432	33240-33244	NCBITaxon:10088	denotes	mice
T18431	33194-33199	UBERON:0000178	denotes	blood
T18430	33164-33175	SO_EXT:0000704	denotes	genetically
T18429	33140-33144	UBERON:0002415	denotes	tail
T18428	33088-33099	SO_EXT:0000704	denotes	genetically
T18427	32924-32928	NCBITaxon:10088	denotes	mice
T18426	32922-32923	SO_EXT:sequence_nullness_or_absence	denotes	-
T18425	32920-32921	SO_EXT:sequence_nullness_or_absence	denotes	-
T18424	32917-32920	PR_EXT:000012867	denotes	Plg
T18423	32878-32882	NCBITaxon:10088	denotes	mice
T18422	32876-32877	SO_EXT:sequence_nullness_or_absence	denotes	-
T18421	32874-32875	SO_EXT:sequence_nullness_or_absence	denotes	-
T18420	32871-32874	PR_EXT:000012867	denotes	Plg
T18419	32705-32709	UBERON:0002415	denotes	tail
T18418	32664-32668	NCBITaxon:10088	denotes	mice
T18417	32661-32663	SO_EXT:wild_type_entity_or_quality	denotes	WT
T18416	32644-32648	NCBITaxon:10088	denotes	mice
T18415	32642-32643	SO_EXT:sequence_nullness_or_absence	denotes	-
T18414	32640-32641	SO_EXT:sequence_nullness_or_absence	denotes	-
T18413	32635-32640	PR_EXT:000014702	denotes	PAI-1
T18412	32632-32633	SO_EXT:sequence_nullness_or_absence	denotes	-
T18411	32630-32631	SO_EXT:sequence_nullness_or_absence	denotes	-
T18410	32627-32630	PR_EXT:000012826	denotes	uPA
T18409	32624-32625	SO_EXT:sequence_nullness_or_absence	denotes	-
T18408	32622-32623	SO_EXT:sequence_nullness_or_absence	denotes	-
T18407	32619-32622	PR_EXT:000012825	denotes	tPA
T18406	32550-32554	NCBITaxon:10088	denotes	mice
T18405	32529-32532	PR_EXT:000012867	denotes	Plg
T18404	32383-32387	NCBITaxon:10088	denotes	mice
T18403	32381-32382	SO_EXT:sequence_nullness_or_absence	denotes	-
T18402	32379-32380	SO_EXT:sequence_nullness_or_absence	denotes	-
T18401	32376-32379	PR_EXT:000012867	denotes	Plg
T18400	32325-32329	NCBITaxon:10088	denotes	mice
T18399	32323-32324	SO_EXT:sequence_nullness_or_absence	denotes	-
T18398	32321-32322	SO_EXT:sequence_nullness_or_absence	denotes	-
T18397	32318-32321	PR_EXT:000012826	denotes	uPA
T18396	32281-32282	SO_EXT:sequence_nullness_or_absence	denotes	-
T18395	32279-32280	SO_EXT:sequence_nullness_or_absence	denotes	-
T18394	32274-32279	PR_EXT:000014702	denotes	PAI-1
T18393	32240-32244	NCBITaxon:10088	denotes	mice
T18392	32238-32239	SO_EXT:sequence_nullness_or_absence	denotes	-
T18391	32236-32237	SO_EXT:sequence_nullness_or_absence	denotes	-
T18390	32233-32236	PR_EXT:000012867	denotes	Plg
T18389	32213-32217	NCBITaxon:10088	denotes	mice
T18388	32123-32127	NCBITaxon:10088	denotes	mice
T18387	32098-32102	UBERON:0002415	denotes	tail
T18386	32081-32089	UBERON:0010210	denotes	thrombus
T18385	32031-32042	GO:0050817	denotes	coagulation
T18384	32004-32011	SO_EXT:0000704	denotes	genetic
T18383	31981-31986	NCBITaxon:10088	denotes	mouse
T18382	31892-31910	GO:0007596	denotes	thrombus formation
T18381	31892-31900	UBERON:0010210	denotes	thrombus
T18380	31865-31873	GO_EXT:reaction_or_response	denotes	response
T18379	31856-31864	CL:0000233	denotes	platelet
T18378	31826-31829	PR_EXT:000012826	denotes	uPA
T18377	31818-31821	PR_EXT:000012867	denotes	Plg
T18376	31799-31803	NCBITaxon:10088	denotes	mice
T18375	31797-31798	SO_EXT:sequence_nullness_or_absence	denotes	-
T18374	31795-31796	SO_EXT:sequence_nullness_or_absence	denotes	-
T18373	31792-31795	PR_EXT:000012826	denotes	uPA
T18372	31786-31787	SO_EXT:sequence_nullness_or_absence	denotes	-
T18371	31784-31785	SO_EXT:sequence_nullness_or_absence	denotes	-
T18370	31781-31784	PR_EXT:000012867	denotes	Plg
T18369	31676-31696	GO:0070527	denotes	platelet aggregation
T18368	31676-31684	CL:0000233	denotes	platelet
T18367	31645-31651	CHEBI_PR_EXT:leptin	denotes	leptin
T18366	31621-31625	UBERON:0002415	denotes	tail
T18365	31570-31599	PR_EXT:000001664	denotes	protease-activated receptor-4
T18364	31570-31597	GO_PR_EXT:proteinase_activated_receptor	denotes	protease-activated receptor
T18363	31544-31556	CHEBI:17089	denotes	glycoprotein
T18362	31535-31543	CL:0000233	denotes	platelet
T18361	31516-31524	CL:0000233	denotes	platelet
T18360	31461-31465	NCBITaxon:10088	denotes	Mice
T18359	31427-31445	GO:0007596	denotes	thrombus formation
T18358	31427-31435	UBERON:0010210	denotes	thrombus
T18357	31405-31412	SO_EXT:0000704	denotes	genetic
T18356	31307-31311	NCBITaxon:10088	denotes	mice
T18355	31293-31296	PR_EXT:000007303	denotes	FIX
T18354	31283-31288	PR_EXT:000007302	denotes	FVIII
T18353	31275-31279	UBERON:0002415	denotes	tail
T18352	31150-31161	GO:0050817	denotes	coagulation
T18351	31133-31142	SO_EXT:sequence_deletion_entity_or_process	denotes	deletions
T18350	31128-31132	SO_EXT:0000704	denotes	gene
T18349	31118-31122	NCBITaxon:10088	denotes	mice
T18348	31082-31089	CHEBI_EXT:59132	denotes	antigen
T18347	31067-31089	PR_EXT:000017364	denotes	von Willebrand antigen
T18346	31015-31019	NCBITaxon:10088	denotes	mice
T18345	30984-30988	NCBITaxon:10088	denotes	mice
T18344	30937-30941	NCBITaxon:10088	denotes	mice
T18343	30925-30933	CHEBI_PR_EXT:protein	denotes	proteins
T18342	30913-30924	GO:0050817	denotes	coagulation
T18341	30900-30908	CL:0000233	denotes	platelet
T18340	30886-30896	GO:0010467	denotes	expression
T18339	30835-30839	NCBITaxon:10088	denotes	mice
T18338	30786-30790	UBERON:0002415	denotes	tail
T18337	30762-30780	GO:0007596	denotes	thrombus formation
T18336	30762-30770	UBERON:0010210	denotes	thrombus
T18335	30721-30729	GO:0065007	denotes	modulate
T18334	30705-30709	UBERON:0010210	denotes	clot
T18333	30627-30631	NCBITaxon:10088	denotes	mice
T18332	30625-30626	SO_EXT:sequence_nullness_or_absence	denotes	-
T18331	30623-30624	SO_EXT:sequence_nullness_or_absence	denotes	-
T18330	30620-30623	PR_EXT:000014702	denotes	PAI
T18329	30593-30597	NCBITaxon:10088	denotes	mice
T18328	30591-30592	SO_EXT:sequence_nullness_or_absence	denotes	-
T18327	30589-30590	SO_EXT:sequence_nullness_or_absence	denotes	-
T18326	30586-30589	PR_EXT:000012867	denotes	Plg
T18325	30543-30561	GO:0007596	denotes	thrombus formation
T18324	30543-30551	UBERON:0010210	denotes	thrombus
T18323	30525-30528	PR_EXT:000012867	denotes	Plg
T18322	30495-30499	NCBITaxon:10088	denotes	mice
T18321	30439-30450	GO:0050817	denotes	coagulation
T18320	30416-30424	CL:0000233	denotes	platelet
T18319	30392-30396	NCBITaxon:10088	denotes	mice
T18318	30386-30389	CHEBI_PR_EXT:leptin	denotes	Lep
T18317	30311-30316	UBERON:0000178	denotes	blood
T18316	30290-30294	NCBITaxon:10088	denotes	mice
T18315	30267-30275	UBERON:0010210	denotes	thrombus
T18314	30185-30189	NCBITaxon:10088	denotes	mice
T18313	30142-30150	UBERON:0001637	denotes	arterial
T18312	30130-30138	UBERON:0005396	denotes	carotids
T18311	29930-29935	UBERON:0000178	denotes	blood
T18310	29857-29861	NCBITaxon:10114	denotes	rats
T18309	29763-29767	NCBITaxon:10088	denotes	mice
T18308	29739-29743	NCBITaxon:10088	denotes	mice
T18307	29693-29702	GO:0007599	denotes	occlusion
T18306	29670-29678	_FRAGMENT	denotes	thrombus
T18305	29670-29688	GO:0007596	denotes	thrombus formation
T18304	29670-29678	UBERON:0010210	denotes	thrombus
T18303	29653-29658	CHEBI:30808	denotes	FeCl3
T18302	29633-29638	CHEBI:30808	denotes	FeCl3
T18301	29612-29626	UBERON:0005396	denotes	carotid artery
T18300	29497-29512	CHEBI_EXT:52217	denotes	pharmacological
T18299	29485-29492	SO_EXT:0000704	denotes	genetic
T18298	29449-29453	NCBITaxon:10088	denotes	mice
T18297	29435-29445	GO:0007596	denotes	thrombosis
T18296	29415-29423	UBERON_EXT:vascular_system_or_vasculature_or_vessel	denotes	vascular
T18295	29392-29397	CHEBI:30808	denotes	FeCl3
T18294	29365-29376	GO_SO_EXT:chromosome	denotes	chromosomes
T18293	29232-29240	UBERON:0001637	denotes	Arterial
T18292	29209-29220	GO_SO_EXT:chromosome	denotes	chromosomes
T18291	29093-29097	NCBITaxon:10088	denotes	mice
T18290	29012-29019	CHEBI_EXT:59132	denotes	antigen
T18289	29006-29011	PR_EXT:000014702	denotes	PAI-1
T18288	28913-28924	GO_SO_EXT:chromosome	denotes	chromosomes
T18287	28864-28875	GO_SO_EXT:chromosome	denotes	chromosomes
T18286	28839-28843	NCBITaxon:10088	denotes	Mice
T18285	28764-28769	SO_EXT:0000704	denotes	genes
T18284	28738-28749	GO_SO_EXT:chromosome	denotes	chromosomes
T18283	28684-28692	CL:0000233	denotes	platelet
T18282	28669-28680	GO:0050817	denotes	coagulation
T18281	28554-28562	GO_EXT:reaction_or_response	denotes	response
T18280	28543-28553	GO:0007596	denotes	thrombotic
T18279	28487-28495	CL:0000233	denotes	platelet
T18278	28467-28471	NCBITaxon:10088	denotes	mice
T18277	28450-28456	CHEBI_PR_EXT:leptin	denotes	leptin
T18276	28425-28434	GO_EXT:reaction_or_response	denotes	responses
T18275	28412-28424	GO:0042730	denotes	fibrinolytic
T18274	28387-28390	PR_EXT:000012867	denotes	Plg
T18273	28375-28379	NCBITaxon:10088	denotes	mice
T18272	28361-28365	SO_EXT:0000704	denotes	gene
T18271	28284-28292	GO_EXT:reaction_or_response	denotes	response
T18270	28273-28283	GO:0007596	denotes	thrombotic
T18269	28197-28201	UBERON:0002415	denotes	tail
T18268	28172-28180	UBERON:0001637	denotes	Arterial
T18267	28153-28159	UBERON:0000055	denotes	vessel
T18266	27998-28002	NCBITaxon:10088	denotes	mice
T18265	27929-27939	GO:0007596	denotes	thrombotic
T18533	36071-36079	UBERON:0001637	denotes	arterial
T18532	36062-36070	GO:0065007	denotes	modulate
T18531	36046-36049	PR_EXT:000012867	denotes	Plg
T18530	36004-36009	SO_EXT:0000704	denotes	genes
T18529	35975-35978	SO_EXT:0000771	denotes	QTL
T18528	35945-35949	NCBITaxon:10088	denotes	mice
T18527	35924-35935	GO_SO_EXT:chromosome	denotes	chromosomes
T18526	35897-35905	CHEBI_PR_EXT:collagen	denotes	collagen
T18525	35890-35896	UBERON:0000055	denotes	vessel
T18524	35879-35885	UBERON:0000479	denotes	tissue
T18523	35853-35864	PR_EXT:000012867	denotes	plasminogen
T18522	35832-35836	UBERON:0002415	denotes	tail
T18521	35788-35796	UBERON_EXT:vascular_system_or_vasculature_or_vessel	denotes	vascular
T18520	35782-35787	CHEBI:30808	denotes	FeCl3
T18519	35756-35776	GO:0007596	denotes	thrombosis formation
T18518	35747-35755	UBERON:0001637	denotes	arterial
T18517	35726-35730	NCBITaxon:10088	denotes	mice
T18516	35603-35606	PR_EXT:000012867	denotes	Plg
T18515	35575-35580	SO_EXT:0000704	denotes	genes
T18514	35501-35514	SO_EXT:coding_sequence	denotes	coding region
T18513	35485-35493	SO_EXT:sequence_upstreamness	denotes	upstream
T18512	35479-35484	SO_EXT:0000704	denotes	genes
T18511	35468-35478	GO:0065007	denotes	regulatory
T18510	35424-35428	NCBITaxon:10088	denotes	mice
T18509	35405-35409	SO_EXT:0000704	denotes	gene
T18508	35390-35404	PR_EXT:000014706	denotes	α2-antiplasmin
T18507	35378-35382	SO_EXT:0000704	denotes	gene
T18506	35372-35377	PR_EXT:000014702	denotes	PAI-1
T18505	35350-35358	SO_EXT:biological_sequence	denotes	sequence
T18504	35340-35349	SO_EXT:0000028	denotes	base pair
T18503	35340-35344	CHEBI_SO_EXT:base	denotes	base
T18502	35336-35339	CHEBI_SO_EXT:DNA	denotes	DNA
T18501	35329-35334	SO_EXT:0000704	denotes	genes
T18500	35292-35302	GO_SO_EXT:chromosome	denotes	chromosome
T18499	35268-35276	CHEBI_PR_EXT:protein	denotes	proteins
T18498	35261-35267	GO:0031012	denotes	matrix
T18497	35247-35256	GO_EXT:0008233	denotes	proteases
T18496	35231-35236	SO_EXT:0000704	denotes	genes
T18495	35216-35219	PR_EXT:000012867	denotes	Plg
T18494	35205-35208	SO_EXT:0000771	denotes	QTL
T18493	35179-35183	NCBITaxon:10088	denotes	mice
T18492	35050-35054	SO_EXT:0000704	denotes	gene
T18491	35046-35049	PR_EXT:000012867	denotes	Plg
T18490	35014-35024	GO_SO_EXT:chromosome	denotes	chromosome
T18489	35001-35005	NCBITaxon:10088	denotes	mice
T18488	34971-34974	GO_SO_EXT:chromosome	denotes	Chr
T18487	34822-34825	PR_EXT:000012867	denotes	Plg
T18486	34774-34778	NCBITaxon:10088	denotes	mice
T18485	34754-34758	NCBITaxon:10088	denotes	mice
T18484	34715-34718	PR_EXT:000012867	denotes	Plg
T18483	34704-34708	NCBITaxon:10088	denotes	mice
T18482	34665-34669	SO_EXT:0000704	denotes	gene
T18481	34661-34664	PR_EXT:000012867	denotes	Plg
T18480	34655-34660	NCBITaxon:10088	denotes	mouse
T18479	34634-34641	SO_EXT:0001023	denotes	allelic
T18478	34614-34628	PR_EXT:000014706	denotes	α2-antiplasmin
T18477	34603-34608	PR_EXT:000014702	denotes	PAI-1
T18476	34598-34601	PR_EXT:000012867	denotes	Plg
T18475	34528-34532	NCBITaxon:10088	denotes	mice
T18474	34514-34518	NCBITaxon:10088	denotes	mice
T18473	34484-34488	NCBITaxon:10088	denotes	mice
T18472	34449-34457	UBERON:0001637	denotes	arterial
T18471	34317-34321	NCBITaxon:10088	denotes	mice
T18470	34214-34217	SO_EXT:0000771	denotes	QTL
T18469	34187-34198	GO_SO_EXT:chromosome	denotes	chromosomes
T18468	34152-34166	PR_EXT:000014706	denotes	α2-antiplasmin
T18467	34141-34146	PR_EXT:000014702	denotes	PAI-1
T14902	27388-27396	UBERON:0001637	denotes	arterial
T14901	27352-27362	GO_SO_EXT:chromosome	denotes	chromosome
T14900	27343-27348	SO_EXT:0000704	denotes	genes
T14899	27279-27287	UBERON:0001637	denotes	arterial
T14898	27249-27253	NCBITaxon:10088	denotes	mice
T14897	27184-27188	NCBITaxon:10088	denotes	mice
T14896	27134-27138	NCBITaxon:10088	denotes	mice
T14895	27110-27114	NCBITaxon:10088	denotes	mice
T14894	27008-27012	NCBITaxon:10088	denotes	mice
T14893	26906-26910	NCBITaxon:10088	denotes	mice
T14892	26822-26827	CHEBI:30808	denotes	FeCl3
T14891	26793-26801	UBERON:0001637	denotes	arterial
T14890	26654-26658	UBERON:0002415	denotes	tail
T14889	26631-26649	GO:0007596	denotes	thrombus formation
T14888	26631-26639	UBERON:0010210	denotes	thrombus
T14887	26622-26630	UBERON:0001637	denotes	arterial
T14098	26061-26065	NCBITaxon:10088	denotes	mice
T14097	26026-26030	NCBITaxon:10088	denotes	mice
T14096	25943-25950	CHEBI_EXT:59132	denotes	antigen
T14095	25937-25942	PR_EXT:000014702	denotes	PAI-1
T14094	25858-25863	PR_EXT:000014702	denotes	PAI-1
T14093	25799-25803	NCBITaxon:10088	denotes	mice
T14092	25732-25737	PR_EXT:000014702	denotes	PAI-1
T14091	25508-25515	CHEBI_EXT:59132	denotes	antigen
T14090	25502-25507	PR_EXT:000014702	denotes	PAI-1
T14089	25484-25488	NCBITaxon:10088	denotes	mice
T14088	25456-25463	CHEBI_EXT:59132	denotes	antigen
T14087	25450-25455	PR_EXT:000014702	denotes	PAI-1
T14086	25201-25208	CHEBI_EXT:59132	denotes	antigen
T14085	25195-25200	PR_EXT:000014702	denotes	PAI-1
T14084	25189-25193	NCBITaxon:10088	denotes	mice
T14083	25165-25169	NCBITaxon:10088	denotes	mice
T14082	25030-25034	NCBITaxon:10088	denotes	mice
T14081	24967-24981	PR_EXT:000014706	denotes	α2-antiplasmin
T14080	24961-24965	NCBITaxon:10088	denotes	mice
T14079	24871-24883	GO:0042730	denotes	Fibrinolytic
T14078	24865-24869	NCBITaxon:10088	denotes	mice
T14077	24824-24831	CHEBI_EXT:59132	denotes	antigen
T14076	24820-24823	PR_EXT:000012867	denotes	Plg
T14075	24780-24784	NCBITaxon:10088	denotes	mice
T14074	24685-24692	CHEBI_EXT:59132	denotes	antigen
T14073	24681-24684	PR_EXT:000012867	denotes	Plg
T14072	24671-24675	NCBITaxon:10088	denotes	mice
T14071	24655-24659	NCBITaxon:10088	denotes	mice
T14070	24624-24634	GO:0005577	denotes	fibrinogen
T14069	24605-24610	PR_EXT:000014702	denotes	PAI-1
T14068	24589-24603	PR_EXT:000014706	denotes	α2-antiplasmin
T14067	24566-24578	GO:0042730	denotes	fibrinolytic
T14066	24557-24564	CHEBI_EXT:59132	denotes	antigen
T14065	24553-24556	PR_EXT:000012867	denotes	Plg
T14064	24534-24538	NCBITaxon:10088	denotes	mice
T14063	24467-24481	PR_EXT:000014706	denotes	α2-antiplasmin
T14062	24451-24456	PR_EXT:000014702	denotes	PAI-1
T14061	24432-24443	GO_SO_EXT:chromosome	denotes	chromosomes
T14060	24411-24414	PR_EXT:000012867	denotes	Plg
T14059	24372-24379	CHEBI_EXT:59132	denotes	antigen
T14058	24366-24371	PR_EXT:000014702	denotes	PAI-1
T11636	20724-20728	NCBITaxon:10088	denotes	mice
T11635	20682-20686	NCBITaxon:10088	denotes	mice
T11634	20656-20670	UBERON:0001013	denotes	adipose tissue
T11633	20645-20652	UBERON:0000055	denotes	vessels
T11632	20633-20641	CHEBI_PR_EXT:collagen	denotes	Collagen
T11631	20616-20620	NCBITaxon:10088	denotes	mice
T11630	20572-20580	CHEBI_PR_EXT:collagen	denotes	collagen
T11629	20480-20484	UBERON:0002415	denotes	tail
T11628	20460-20468	CHEBI_PR_EXT:collagen	denotes	Collagen
T11627	20440-20458	GO:0007596	denotes	thrombus formation
T11626	20440-20448	UBERON:0010210	denotes	thrombus
T11625	20402-20410	GO_PATO_EXT:biological_adhesion_or_adhesiveness	denotes	adhesive
T11624	20393-20401	CL:0000233	denotes	platelet
T11623	20373-20381	CHEBI_PR_EXT:collagen	denotes	collagen
T11622	20305-20310	UBERON:0002415	denotes	tails
T11621	20253-20258	CHEBI_EXT:eosin	denotes	Eosin
T11620	20241-20252	CHEBI:51686	denotes	Hematoxylin
T11619	20228-20237	UBERON_EXT:cartilage_element_or_tissue	denotes	cartilage
T11618	20223-20227	UBERON_EXT:bone_element_or_tissue	denotes	bone
T11617	20195-20211	UBERON:0001821	denotes	sebaceous glands
T11616	20179-20193	UBERON:0002073	denotes	hair follicles
T11615	20048-20053	CHEBI_EXT:eosin	denotes	Eosin
T11614	20036-20047	CHEBI:51686	denotes	Hematoxylin
T11613	20013-20017	NCBITaxon:10088	denotes	mice
T11612	19988-19992	UBERON:0002415	denotes	tail
T11611	19860-19864	NCBITaxon:10088	denotes	mice
T11610	19847-19852	UBERON:0002415	denotes	tails
T11609	19813-19817	UBERON:0002415	denotes	Tail
T10950	19797-19802	NCBITaxon:10088	denotes	mouse
T10949	19782-19785	PR_EXT:000012867	denotes	Plg
T10948	19687-19696	GO_EXT:biological_movement_or_translocation_process	denotes	migration
T10947	19632-19636	NCBITaxon:10088	denotes	mice
T10946	19613-19619	UBERON:0001969	denotes	plasma
T10945	19592-19596	NCBITaxon:10088	denotes	mice
T10944	19572-19578	UBERON:0001969	denotes	plasma
T10943	19565-19568	PR_EXT:000012867	denotes	Plg
T10942	19520-19526	UBERON:0001969	denotes	plasma
T10941	19452-19456	NCBITaxon:10088	denotes	mice
T10940	19431-19435	NCBITaxon:10088	denotes	mice
T10939	19346-19350	NCBITaxon:10088	denotes	mice
T10938	19304-19310	UBERON:0001969	denotes	plasma
T10937	19281-19289	MOP:0000569	denotes	reducing
T10936	19266-19269	CHEBI:8984	denotes	SDS
T10935	19171-19174	PR_EXT:000012867	denotes	Plg
T10934	19143-19152	GO_EXT:biological_movement_or_translocation_process	denotes	migration
T10933	19103-19113	GO_EXT:macromolecule_denaturation	denotes	denaturing
T10932	19086-19093	MOP:0000569	denotes	reduced
T10931	19073-19080	MOP:0000569	denotes	reduced
T10930	19028-19032	NCBITaxon:10088	denotes	mice
T10929	18997-19003	UBERON:0001969	denotes	plasma
T10928	18991-18995	NCBITaxon:10088	denotes	mice
T10927	18974-18977	PR_EXT:000012867	denotes	Plg
T10926	18945-18952	CHEBI_PR_EXT:protein	denotes	protein
T10925	18907-18911	NCBITaxon:10088	denotes	mice
T10924	18870-18880	GO:0005577	denotes	fibrinogen
T10923	18784-18788	NCBITaxon:10088	denotes	mice
T10922	18755-18759	NCBITaxon:10088	denotes	mice
T10921	18709-18723	PR_EXT:000014706	denotes	α2-anitplasmin
T10920	18689-18694	PR_EXT:000014702	denotes	PAI-1
T10919	18666-18678	GO:0042730	denotes	fibrinolytic
T10918	18647-18651	NCBITaxon:10088	denotes	mice
T10917	18631-18635	NCBITaxon:10088	denotes	mice
T10916	18587-18590	PR_EXT:000012867	denotes	Plg
T10915	18582-18586	NCBITaxon:10088	denotes	mice
T10914	18554-18559	PR_EXT:000014702	denotes	PAI-1
T10913	18546-18549	PR_EXT:000012867	denotes	Plg
T10206	17688-17692	PR_EXT:000007302	denotes	VIII
T10205	17681-17683	PR_EXT:000007303	denotes	IX
T10204	17677-17679	PR_EXT:000007295	denotes	XI
T10203	17664-17671	_FRAGMENT	denotes	Factors
T10202	17664-17675	PR_EXT:000007296	denotes	Factors XII
T10201	17650-17675	GO:0002542	denotes	activation of Factors XII
T10200	17581-17594	PR_EXT:000001940	denotes	tissue factor
T10199	17581-17587	UBERON:0000479	denotes	tissue
T10198	17567-17577	PR_EXT:000007301	denotes	Factor VII
T10197	17522-17551	GO:0007598	denotes	extrinsic coagulation pathway
T10196	17453-17467	CHEBI_PR_EXT:thromboplastin	denotes	thromboplastin
T10195	17409-17420	CHEBI_PR_EXT:prothrombin	denotes	prothrombin
T10194	17331-17342	GO:0050817	denotes	coagulation
T10193	17295-17299	NCBITaxon:10088	denotes	mice
T10192	17258-17275	GO:0007596	denotes	blood coagulation
T10191	17258-17263	UBERON:0000178	denotes	blood
T9399	17227-17230	PR_EXT:000012867	denotes	Plg
T9398	17209-17219	GO:0065007	denotes	regulation
T9397	17081-17086	PR_EXT:000014702	denotes	PAI-1
T9396	17002-17005	PR_EXT:000012867	denotes	Plg
T9395	16985-16989	NCBITaxon:10088	denotes	mice
T9394	16883-16887	NCBITaxon:10088	denotes	mice
T9393	16881-16882	SO_EXT:sequence_nullness_or_absence	denotes	-
T9392	16879-16880	SO_EXT:sequence_nullness_or_absence	denotes	-
T9391	16874-16879	PR_EXT:000014702	denotes	PAI-1
T9390	16854-16856	SO_EXT:wild_type_entity_or_quality	denotes	WT
T9389	16837-16841	NCBITaxon:10088	denotes	mice
T9388	16835-16836	SO_EXT:sequence_nullness_or_absence	denotes	-
T9387	16833-16834	SO_EXT:sequence_nullness_or_absence	denotes	-
T9386	16830-16833	PR_EXT:000012867	denotes	Plg
T9385	16758-16762	NCBITaxon:10088	denotes	mice
T9384	16756-16757	SO_EXT:sequence_nullness_or_absence	denotes	-
T9383	16754-16755	SO_EXT:sequence_nullness_or_absence	denotes	-
T9382	16749-16754	PR_EXT:000014702	denotes	PAI-1
T9381	16743-16744	SO_EXT:sequence_nullness_or_absence	denotes	-
T9380	16741-16742	SO_EXT:sequence_nullness_or_absence	denotes	-
T9379	16738-16741	PR_EXT:000012867	denotes	Plg
T9378	16690-16702	GO:0042730	denotes	fibrinolytic
T9377	16648-16652	NCBITaxon:10088	denotes	mice
T9376	16631-16635	NCBITaxon:10088	denotes	mice
T9375	16625-16628	CHEBI_PR_EXT:leptin	denotes	Lep
T9374	16554-16558	NCBITaxon:10088	denotes	mice
T9373	16537-16541	NCBITaxon:10088	denotes	mice
T9372	16336-16344	UBERON:0010210	denotes	thrombus
T9371	15698-15718	GO:0070527	denotes	platelet aggregation
T9370	15698-15706	CL:0000233	denotes	platelet
T9369	15679-15683	NCBITaxon:10088	denotes	mice
T9368	15560-15568	CL:0000233	denotes	platelet
T8035	14057-14061	NCBITaxon:10088	denotes	mice
T8034	14032-14036	NCBITaxon:10088	denotes	mice
T8033	13952-13956	NCBITaxon:10088	denotes	mice
T8032	13897-13902	GO_UBERON_EXT:lumen	denotes	lumen
T8031	13885-13893	UBERON:0010210	denotes	thrombus
T8030	13830-13834	NCBITaxon:10088	denotes	mice
T8029	13813-13817	NCBITaxon:10088	denotes	mice
T8028	13750-13755	GO_UBERON_EXT:lumen	denotes	lumen
T8027	13674-13682	UBERON:0005396	denotes	carotids
T8026	13462-13467	UBERON:0000178	denotes	blood
T8025	13453-13457	NCBITaxon:10088	denotes	mice
T8024	13419-13423	NCBITaxon:10088	denotes	mice
T8023	13329-13334	CHEBI:30808	denotes	FeCl3
T8022	13312-13317	UBERON:0000178	denotes	blood
T8021	13100-13104	NCBITaxon:10088	denotes	mice
T8020	13039-13043	NCBITaxon:10088	denotes	mice
T8019	13004-13009	CHEBI:30808	denotes	FeCl3
T8018	12985-12989	NCBITaxon:10088	denotes	mice
T8017	12948-12952	NCBITaxon:10088	denotes	mice
T8016	12900-12904	NCBITaxon:10088	denotes	mice
T8015	12839-12857	GO:0007599	denotes	thrombus occlusion
T8014	12839-12847	UBERON:0010210	denotes	thrombus
T8013	12830-12838	UBERON:0001637	denotes	arterial
T8012	12772-12777	NCBITaxon:10088	denotes	mouse
T8011	12745-12753	UBERON:0010210	denotes	thrombus
T8010	12695-12705	GO:0007596	denotes	thrombosis
T8009	12686-12694	UBERON:0001637	denotes	arterial
T8008	12631-12645	UBERON:0005396	denotes	cartoid artery
T8007	12625-12630	CHEBI:30808	denotes	FeCl3
T8006	12616-12620	NCBITaxon:10088	denotes	mice
T8005	12583-12601	GO:0007596	denotes	thrombus formation
T6808	11928-11933	NCBITaxon:10088	denotes	mouse
T6807	11824-11829	GO_UBERON_EXT:lumen	denotes	lumen
T6806	11816-11823	UBERON:0005396	denotes	carotid
T6805	11646-11650	UBERON:0002415	denotes	tail
T6804	11625-11633	CHEBI_PR_EXT:collagen	denotes	collagen
T6803	11483-11491	UBERON:0005396	denotes	carotids
T6802	11466-11471	UBERON:0002415	denotes	tails
T6392	11370-11380	GO:0005577	denotes	fibrinogen
T6391	11364-11369	NCBITaxon:10088	denotes	mouse
T6390	11338-11348	GO:0042571	denotes	antibodies
T6389	11302-11312	GO:0005577	denotes	fibrinogen
T6388	11258-11267	CHEBI_EXT:polyatomic_entity_or_group	denotes	Molecular
T6387	11248-11256	GO:0042571	denotes	antibody
T6386	11242-11247	NCBITaxon:10088	denotes	mouse
T6385	11162-11176	PR_EXT:000014706	denotes	α2-antiplasmin
T6384	11156-11161	NCBITaxon:10088	denotes	mouse
T6383	11121-11125	NCBITaxon:10088	denotes	mice
T6382	11107-11110	PR_EXT:000012867	denotes	Plg
T6381	11098-11103	PR_EXT:000014702	denotes	PAI-1
T6380	11086-11092	UBERON:0001969	denotes	plasma
T6379	11018-11024	CHEBI:5054	denotes	fibrin
T6378	10982-10994	GO:0042730	denotes	fibrinolytic
T6377	10951-10962	CHEBI_EXT:75050	denotes	chromogenic
T6376	10925-10928	PR_EXT:000012867	denotes	Plg
T6375	10865-10870	PR_EXT:000014702	denotes	PAI-1
T6374	10859-10864	NCBITaxon:10088	denotes	mouse
T6373	10846-10854	GO:0042571	denotes	antibody
T6372	10802-10807	PR_EXT:000014702	denotes	PAI-1
T6371	10796-10801	NCBITaxon:10088	denotes	mouse
T6370	10785-10790	NCBITaxon:9940	denotes	sheep
T6369	10728-10735	CHEBI_EXT:59132	denotes	antigen
T6368	10722-10727	PR_EXT:000014702	denotes	PAI-1
T6367	10644-10649	PR_EXT:000014702	denotes	PAI-1
T6366	10600-10611	GO:0050817	denotes	Coagulation
T6365	10522-10536	CHEBI_PR_EXT:thromboplastin	denotes	thromboplastin
T6364	10479-10490	CHEBI_PR_EXT:prothrombin	denotes	prothrombin
T6363	10448-10455	CHEBI_EXT:33893	denotes	reagent
T6362	10418-10423	UBERON:0000178	denotes	blood
T6361	10359-10366	UBERON:0001697	denotes	orbital
T6360	10324-10334	CHEBI:6015	denotes	Isoflurane
T6359	10306-10318	CHEBI_EXT:anaesthetic_process	denotes	anesthetized
T6358	10296-10300	NCBITaxon:10088	denotes	Mice
T6357	10283-10288	PR_EXT:000014702	denotes	PAI-1
T6356	10266-10278	GO:0042730	denotes	fibrinolytic
T6355	10254-10264	GO:0005577	denotes	fibrinogen
T6354	10238-10252	PR_EXT:000014706	denotes	α2-antiplasmin
T6353	10233-10236	PR_EXT:000012867	denotes	Plg
T6352	10220-10231	GO:0050817	denotes	Coagulation
T5304	9626-9634	UBERON_EXT:vascular_system_or_vasculature_or_vessel	denotes	vascular
T5303	9597-9601	NCBITaxon:10088	denotes	mice
T5302	9575-9579	UBERON_EXT:body	denotes	body
T5301	9477-9482	UBERON:0000178	denotes	Blood
T5300	9290-9295	UBERON:0000178	denotes	blood
T5299	9274-9280	UBERON:0001637	denotes	artery
T5298	9241-9249	CHEBI:75958	denotes	solution
T5297	9235-9240	CHEBI:30808	denotes	FeCl3
T5296	9154-9168	UBERON:0005396	denotes	carotid artery
T5295	9111-9119	CHEBI:75958	denotes	solution
T5294	9105-9110	CHEBI:30808	denotes	FeCl3
T5293	9004-9010	UBERON:0001637	denotes	artery
T5292	8877-8903	UBERON:0001536	denotes	left common carotid artery
T5291	8842-8850	UBERON:0005434	denotes	cervical
T5290	8793-8801	CHEBI:6121	denotes	ketamine
T5289	8775-8787	CHEBI_EXT:anaesthetic_process	denotes	anesthetized
T5288	8765-8769	NCBITaxon:10088	denotes	Mice
T5287	8729-8735	UBERON:0000055	denotes	vessel
T5286	8713-8718	CHEBI:30808	denotes	FeCl3
T5285	8696-8711	CHEBI:30808	denotes	ferric chloride
T5284	8678-8692	UBERON:0005396	denotes	carotid artery
T5283	8650-8670	GO:0007596	denotes	thrombosis formation
T5282	8624-8632	UBERON_EXT:vascular_system_or_vasculature_or_vessel	denotes	Vascular
T5751	10090-10105	CHEBI_EXT:saline_solution	denotes	saline solution
T5750	10063-10067	UBERON:0002415	denotes	tail
T5749	9951-9957	CHEBI_EXT:saline_solution	denotes	saline
T5748	9896-9900	UBERON:0002415	denotes	tail
T5747	9878-9884	CHEBI_EXT:saline_solution	denotes	saline
T5746	9853-9857	UBERON:0002415	denotes	tail
T5745	9837-9842	CHEBI:15377	denotes	water
T5744	9817-9823	CHEBI_EXT:saline_solution	denotes	saline
T5743	9780-9784	UBERON:0002415	denotes	tail
T5742	9737-9745	CHEBI:6121	denotes	ketamine
T5741	9719-9731	CHEBI_EXT:anaesthetic_process	denotes	anesthetized
T5740	9709-9713	NCBITaxon:10088	denotes	mice
T5739	9688-9692	UBERON:0002415	denotes	tail
T4563	8571-8577	NCBITaxon:33208	denotes	Animal
T4562	8477-8483	NCBITaxon:33208	denotes	animal
T4561	8394-8397	CHEBI_UBERON_EXT:triglyceride_or_adipose_tissue	denotes	fat
T4560	8380-8387	CHEBI_PR_EXT:protein	denotes	protein
T4559	8317-8320	GO:0007631	denotes	fed
T4558	8307-8311	NCBITaxon:10088	denotes	Mice
T4557	8289-8294	CHEBI:15377	denotes	water
T4556	8280-8284	CHEBI_EXT:33290	denotes	food
T4555	8158-8162	NCBITaxon:10088	denotes	Mice
T4554	8091-8101	CHEBI_GO_EXT:biological_process_or_quality_or_role	denotes	Biological
T4553	8079-8083	GO_EXT:breeding	denotes	bred
T4552	8058-8062	NCBITaxon:10088	denotes	mice
T4551	8012-8023	GO_EXT:biological_movement_or_translocation_process	denotes	transferred
T4550	8002-8006	NCBITaxon:10088	denotes	mice
T4549	7976-7984	GO_EXT:breeding	denotes	Breeding
T4548	7960-7963	UBERON:0001690	denotes	ear
T4547	7881-7882	SO_EXT:sequence_nullness_or_absence	denotes	-
T4546	7879-7880	SO_EXT:sequence_nullness_or_absence	denotes	-
T4545	7876-7879	PR_EXT:000012867	denotes	Plg
T4544	7873-7874	SO_EXT:sequence_nullness_or_absence	denotes	-
T4543	7871-7872	SO_EXT:normal_or_wild_type_or_present	denotes	+
T4542	7868-7871	PR_EXT:000012867	denotes	Plg
T4541	7865-7866	SO_EXT:normal_or_wild_type_or_present	denotes	+
T4540	7863-7864	SO_EXT:normal_or_wild_type_or_present	denotes	+
T4539	7860-7863	PR_EXT:000012867	denotes	Plg
T4538	7849-7858	SO_EXT:genotype_or_entity_with_genotype	denotes	Genotypes
T4537	7839-7847	GO_EXT:breeding	denotes	breeding
T4536	7802-7805	PR_EXT:000012867	denotes	Plg
T4535	7783-7792	GO:0000003	denotes	reproduce
T4534	7771-7775	NCBITaxon:10088	denotes	mice
T4533	7769-7770	SO_EXT:sequence_nullness_or_absence	denotes	-
T4532	7767-7768	SO_EXT:sequence_nullness_or_absence	denotes	-
T4531	7764-7767	PR_EXT:000012867	denotes	Plg
T4530	7754-7758	NCBITaxon:10088	denotes	mice
T4529	7675-7679	NCBITaxon:10088	denotes	mice
T4528	7567-7571	NCBITaxon:10088	denotes	mice
T4527	7565-7566	SO_EXT:sequence_nullness_or_absence	denotes	-
T4526	7563-7564	SO_EXT:sequence_nullness_or_absence	denotes	-
T4525	7560-7563	PR_EXT:000012867	denotes	Plg
T4524	7457-7461	NCBITaxon:10088	denotes	mice
T4523	7439-7440	SO_EXT:sequence_nullness_or_absence	denotes	-
T4522	7437-7438	SO_EXT:sequence_nullness_or_absence	denotes	-
T4521	7432-7437	PR_EXT:000014702	denotes	PAI-1
T4520	7426-7430	NCBITaxon:10088	denotes	mice
T4519	7406-7415	CHEBI_EXT:35222	denotes	inhibitor
T4518	7391-7394	_FRAGMENT	denotes	Plg
T4517	7396-7415	PR_EXT:000014702	denotes	activator inhibitor
T4516	7378-7389	_FRAGMENT	denotes	plasminogen
T4515	7364-7368	SO_EXT:0000704	denotes	gene
T4514	7329-7332	CHEBI_PR_EXT:leptin	denotes	Lep
T4513	7290-7294	NCBITaxon:10088	denotes	Mice
T3129	7268-7278	GO:0007596	denotes	thrombosis
T3128	7252-7263	GO:0007599	denotes	haemostasis
T3127	7197-7204	SO_EXT:0000704	denotes	genetic
T3126	7140-7143	SO_EXT:0000771	denotes	QTL
T3125	7030-7038	UBERON:0001637	denotes	arterial
T3124	6929-6949	GO:0070527	denotes	platelet aggregation
T3123	6929-6937	CL:0000233	denotes	platelet
T3122	6914-6925	GO:0050817	denotes	coagulation
T3121	6878-6888	GO:0007596	denotes	thrombotic
T3120	6856-6860	NCBITaxon:10088	denotes	mice
T3119	6767-6779	GO:0042730	denotes	fibrinolysis
T3118	6751-6762	GO:0050817	denotes	coagulation
T3117	6714-6718	UBERON:0002415	denotes	tail
T3116	6691-6699	UBERON_EXT:vascular_system_or_vasculature_or_vessel	denotes	vascular
T3115	6675-6690	CHEBI:30808	denotes	ferric chloride
T3114	6646-6656	GO:0007596	denotes	thrombotic
T3113	6634-6638	NCBITaxon:10088	denotes	mice
T3112	6548-6554	SO_EXT:0001026	denotes	genome
T3111	6504-6507	SO_EXT:0000771	denotes	QTL
T3110	6446-6457	CHEBI_SO_EXT:amino_acid	denotes	amino acids
T3109	6439-6445	UBERON:0001969	denotes	plasma
T3108	6421-6428	CHEBI:15889	denotes	sterols
T3107	6388-6396	GO_PATO_EXT:biological_behavior	denotes	behavior
T3106	6304-6307	SO_EXT:0000771	denotes	QTL
T3105	6228-6231	SO_EXT:0000771	denotes	QTL
T3104	6199-6202	SO_EXT:0000771	denotes	QTL
T3103	6131-6137	SO_EXT:0001026	denotes	genome
T3102	6115-6118	SO_EXT:0000771	denotes	QTL
T3101	6093-6097	NCBITaxon:10088	denotes	mice
T3100	6048-6058	GO_SO_EXT:chromosome	denotes	chromosome
T3099	6028-6031	SO_EXT:0000771	denotes	QTL
T3098	5912-5916	NCBITaxon:10088	denotes	mice
T3097	5892-5902	GO_SO_EXT:chromosome	denotes	chromosome
T3096	5857-5867	GO_SO_EXT:chromosome	denotes	chromosome
T3095	5768-5775	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	markers
T3094	5760-5775	SO_EXT:0001645	denotes	Genetic markers
T3093	5754-5758	NCBITaxon:10088	denotes	mice
T3092	5659-5667	GO_EXT:breeding	denotes	breeding
T3091	5642-5648	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T3090	5590-5602	SO_EXT:sequence_substitution_entity_or_process	denotes	substitution
T3089	5579-5589	GO_SO_EXT:chromosome	denotes	chromosome
T3088	5568-5569	PR_EXT:000014702	denotes	A
T7164	12343-12347	NCBITaxon:10088	denotes	mice
T7163	12173-12177	NCBITaxon:10088	denotes	mice
T7162	12171-12172	SO_EXT:sequence_nullness_or_absence	denotes	-
T7161	12169-12170	SO_EXT:sequence_nullness_or_absence	denotes	-
T7160	12164-12169	PR_EXT:000014702	denotes	PAI-1
T7159	12157-12160	CHEBI_PR_EXT:leptin	denotes	Lep
T7158	12082-12083	SO_EXT:sequence_nullness_or_absence	denotes	-
T7157	12080-12081	SO_EXT:sequence_nullness_or_absence	denotes	-
T7156	12077-12080	PR_EXT:000012867	denotes	Plg
T7155	12069-12071	SO_EXT:wild_type_entity_or_quality	denotes	WT
T7154	12058-12067	SO_EXT:wild_type_entity_or_quality	denotes	wild-type
T7153	12041-12045	NCBITaxon:10088	denotes	mice
T8004	12583-12591	UBERON:0010210	denotes	thrombus
T8003	12574-12582	UBERON:0001637	denotes	arterial
T9367	15548-15552	NCBITaxon:10088	denotes	mice
T9366	15542-15545	CHEBI_PR_EXT:leptin	denotes	Lep
T9365	15517-15521	NCBITaxon:10088	denotes	mice
T9364	15497-15501	NCBITaxon:10088	denotes	mice
T9363	15495-15496	SO_EXT:sequence_nullness_or_absence	denotes	-
T9362	15493-15494	SO_EXT:sequence_nullness_or_absence	denotes	-
T9361	15488-15493	PR_EXT:000014702	denotes	PAI-1
T9360	15435-15439	NCBITaxon:10088	denotes	mice
T9359	15432-15434	SO_EXT:wild_type_entity_or_quality	denotes	WT
T9358	15415-15419	NCBITaxon:10088	denotes	mice
T9357	15413-15414	SO_EXT:sequence_nullness_or_absence	denotes	-
T9356	15411-15412	SO_EXT:sequence_nullness_or_absence	denotes	-
T9355	15408-15411	PR_EXT:000012867	denotes	Plg
T9354	15328-15332	NCBITaxon:10088	denotes	mice
T9353	15243-15247	NCBITaxon:10088	denotes	mice
T9352	15237-15240	CHEBI_PR_EXT:leptin	denotes	Lep
T9351	15211-15219	CL:0000233	denotes	platelet
T9350	15147-15167	GO:0070527	denotes	platelet aggregation
T10214	17988-17999	GO:0050817	denotes	coagulation
T10213	17932-17937	NCBITaxon:10088	denotes	mouse
T10212	17881-17885	NCBITaxon:10088	denotes	mice
T10211	17821-17835	GO:0050817	denotes	clot formation
T10210	17814-17825	UBERON:0010210	denotes	fibrin clot
T10209	17814-17820	CHEBI:5054	denotes	fibrin
T10208	17790-17798	CHEBI:9574	denotes	thrombin
T10207	17734-17742	CHEBI_PR_EXT:factor_X	denotes	Factor X
T12714	23737-23748	GO_SO_EXT:chromosome	denotes	chromosomes
T12713	23599-23610	GO_SO_EXT:chromosome	denotes	chromosomes
T12712	23331-23335	NCBITaxon:10088	denotes	mice
T12711	23283-23287	NCBITaxon:10088	denotes	mice
T12710	23158-23162	NCBITaxon:10088	denotes	mice
T12709	23130-23134	NCBITaxon:10088	denotes	mice
T12708	23099-23103	NCBITaxon:10088	denotes	mice
T12707	22587-22591	NCBITaxon:10088	denotes	mice
T12706	22525-22529	NCBITaxon:10088	denotes	mice
T12705	22410-22414	NCBITaxon:10088	denotes	mice
T12704	22264-22268	NCBITaxon:10088	denotes	mice
T12703	22218-22222	NCBITaxon:10088	denotes	mice
T12702	22076-22080	NCBITaxon:10088	denotes	mice
T12701	22052-22056	NCBITaxon:10088	denotes	mice
T12700	21880-21884	NCBITaxon:10088	denotes	mice
T12699	21711-21715	NCBITaxon:10088	denotes	mice
T12698	21622-21632	GO:0007596	denotes	thrombosis
T12697	21607-21617	GO:0007599	denotes	hemostasis
T12696	21550-21554	UBERON:0002415	denotes	tail
T12695	21514-21517	SO_EXT:0000771	denotes	QTL
T12694	21497-21508	GO_SO_EXT:chromosome	denotes	chromosomes
T12693	21460-21464	UBERON:0002415	denotes	Tail
T18461	33971-33991	GO:0031012	denotes	extracellular matrix
T20399	36661-36671	GO:0007596	denotes	thrombotic
T20398	36637-36644	SO_EXT:0000704	denotes	genetic
T20397	36463-36471	CL_GO_EXT:cell	denotes	cellular
T20396	36458-36478	GO:0031012	denotes	extracellular matrix
T20395	36451-36457	UBERON:0000055	denotes	vessel
T20394	36422-36426	UBERON:0002415	denotes	tail
T20393	36410-36420	GO:0007596	denotes	thrombosis
T20392	36401-36409	UBERON:0001637	denotes	arterial
T20562	5003-5007	NCBITaxon:10088	denotes	mice
T20563	5066-5074	UBERON_EXT:vascular_system_or_vasculature_or_vessel	denotes	vascular
T21151	16293-16301	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T21150	16284-16288	NCBITaxon:10088	denotes	mice
T21149	16243-16247	NCBITaxon:10088	denotes	mice
T21148	16240-16242	SO_EXT:wild_type_entity_or_quality	denotes	WT
T21147	16077-16080	CHEBI_PR_EXT:leptin	denotes	Lep
T21146	16071-16072	SO_EXT:sequence_nullness_or_absence	denotes	-
T21145	16069-16070	SO_EXT:sequence_nullness_or_absence	denotes	-
T21144	16064-16069	PR_EXT:000014702	denotes	PAI-1
T21143	16001-16002	SO_EXT:sequence_nullness_or_absence	denotes	-
T21142	15999-16000	SO_EXT:sequence_nullness_or_absence	denotes	-
T21141	15996-15999	PR_EXT:000012867	denotes	Plg
T21140	15989-15991	SO_EXT:wild_type_entity_or_quality	denotes	WT
T21139	15834-15838	NCBITaxon:10088	denotes	mice
T21138	15832-15833	SO_EXT:sequence_nullness_or_absence	denotes	-
T21137	15830-15831	SO_EXT:sequence_nullness_or_absence	denotes	-
T21136	15825-15830	PR_EXT:000014702	denotes	PAI-1
T21135	15819-15820	SO_EXT:sequence_nullness_or_absence	denotes	-
T21134	15817-15818	SO_EXT:sequence_nullness_or_absence	denotes	-
T21133	15814-15817	PR_EXT:000012867	denotes	Plg
T21132	15807-15810	CHEBI_PR_EXT:leptin	denotes	Lep
T22994	27703-27707	NCBITaxon:10088	denotes	mice
T22993	27662-27666	NCBITaxon:10088	denotes	mice
T22992	27599-27610	GO_SO_EXT:chromosome	denotes	chromosomes
T22991	27590-27594	NCBITaxon:10088	denotes	mice
T22990	27516-27520	NCBITaxon:10088	denotes	mice
T22989	27423-27431	UBERON:0001637	denotes	Arterial
T23140	18128-18133	NCBITaxon:10088	denotes	mouse
T23139	18077-18088	PR_EXT:000012867	denotes	Plasminogen
T23138	18061-18072	GO:0050817	denotes	Coagulation
T9349	15147-15155	CL:0000233	denotes	platelet
T9348	15128-15132	NCBITaxon:10088	denotes	mice
T9347	15122-15125	CHEBI_PR_EXT:leptin	denotes	Lep
T9346	15094-15098	NCBITaxon:10088	denotes	mice
T9345	15092-15093	SO_EXT:sequence_nullness_or_absence	denotes	-
T9344	15090-15091	SO_EXT:sequence_nullness_or_absence	denotes	-
T9343	15087-15090	PR_EXT:000014702	denotes	PAI
T9342	15081-15082	SO_EXT:sequence_nullness_or_absence	denotes	-
T9341	15079-15080	SO_EXT:sequence_nullness_or_absence	denotes	-
T9340	15076-15079	PR_EXT:000012867	denotes	Plg
T9339	15064-15074	GO:0007596	denotes	thrombosis
T9338	15055-15059	NCBITaxon:10088	denotes	mice
T9337	15049-15052	CHEBI_PR_EXT:leptin	denotes	Lep
T9336	15037-15047	GO:0007599	denotes	hemostasis
T9335	15006-15010	NCBITaxon:10088	denotes	mice
T9334	14905-14909	NCBITaxon:10088	denotes	mice
T9333	14885-14889	NCBITaxon:10088	denotes	mice
T9332	14802-14807	NCBITaxon:10088	denotes	mouse
T9331	14677-14683	CHEBI_EXT:saline_solution	denotes	saline
T9330	14664-14668	UBERON:0002415	denotes	tail
T9329	14621-14625	UBERON:0002415	denotes	tail
T9328	14564-14574	GO:0007599	denotes	hemostatic
T9327	14524-14528	NCBITaxon:10088	denotes	mice
T940	42-52	GO:0007599	denotes	hemostasis
T1001	2409-2417	GO_EXT:reaction_or_response	denotes	response
T1002	2421-2429	UBERON_EXT:vascular_system_or_vasculature_or_vessel	denotes	vascular
T1003	2445-2455	GO:0007596	denotes	thrombosis
T1004	2464-2468	UBERON:0002415	denotes	tail
T1005	2529-2536	SO_EXT:0000704	denotes	genetic
T1006	2553-2563	GO:0007596	denotes	thrombotic
T3026	2634-2648	UBERON:0004535	denotes	cardiovascular
T3027	2683-2690	SO_EXT:0000704	denotes	genetic
T3028	2691-2700	SO_EXT:sequence_alteration_entity_or_process	denotes	mutations
R455	T3084	T3083	_lexicallyChainedTo	chromosome,location(s) on
R1203	T4517	T4516	_lexicallyChainedTo	activator inhibitor,plasminogen
R1204	T4517	T4518	_lexicallyChainedTo	activator inhibitor,Plg
R3065	T10204	T10203	_lexicallyChainedTo	XI,Factors
R3066	T10205	T10203	_lexicallyChainedTo	IX,Factors
R3067	T10206	T10203	_lexicallyChainedTo	VIII,Factors
R4735	T18307	T18306	_lexicallyChainedTo	occlusion,thrombus
R4736	T18459	T18458	_lexicallyChainedTo	proteins,metabolism of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id	Subject	Object	Predicate	Lexical cue
T894	353-359	UBERON:0000055	denotes	vessel
T895	413-420	SO:0000704	denotes	genetic
T896	461-469	GO:0065007	denotes	regulate
T897	470-480	GO:0007596	denotes	thrombosis
T898	485-495	GO:0007599	denotes	hemostasis
T899	541-551	GO:0007596	denotes	thrombosis
T900	556-566	GO:0007599	denotes	hemostasis
T901	706-710	NCBITaxon:10088	denotes	mice
T902	745-755	GO:0007596	denotes	thrombosis
T903	760-770	GO:0007599	denotes	hemostasis
T904	774-782	UBERON:0010210	denotes	thrombus
T905	802-816	UBERON:0005396	denotes	carotid artery
T906	847-854	UBERON:0005396	denotes	carotid
T907	858-873	CHEBI:30808	denotes	ferric chloride
T908	878-883	UBERON:0000178	denotes	blood
T909	908-914	UBERON:0000055	denotes	vessel
T910	981-991	GO:0007596	denotes	thrombosis
T911	996-1006	GO:0007599	denotes	hemostasis
T912	1043-1047	UBERON:0002415	denotes	tail
T913	1196-1200	UBERON:0002415	denotes	tail
T914	1226-1234	UBERON:0010210	denotes	Thrombus
T915	1226-1244	GO:0007599	denotes	Thrombus occlusion
T916	1284-1288	NCBITaxon:10088	denotes	mice
T917	1310-1314	NCBITaxon:10088	denotes	mice
T918	1316-1320	UBERON:0002415	denotes	Tail
T919	1421-1425	NCBITaxon:10088	denotes	mice
T920	1447-1451	NCBITaxon:10088	denotes	mice
T921	1453-1464	GO:0050817	denotes	Coagulation
T922	1475-1479	UBERON:0002415	denotes	tail
T923	1509-1513	UBERON:0002415	denotes	tail
T924	1563-1567	NCBITaxon:10088	denotes	mice
T925	1725-1729	NCBITaxon:10088	denotes	mice
T926	1731-1735	NCBITaxon:10088	denotes	Mice
T927	1813-1817	NCBITaxon:10088	denotes	mice
T928	2039-2047	UBERON:0001637	denotes	arterial
T929	2048-2058	GO:0007596	denotes	thrombosis
T930	2063-2074	GO:0007599	denotes	haemostasis
T931	2116-2120	NCBITaxon:10088	denotes	mice
T932	2325-2328	SO:0000771	denotes	QTL
T933	2370-2377	SO:0000704	denotes	genetic
T934	2445-2455	GO:0007596	denotes	thrombosis
T935	2464-2468	UBERON:0002415	denotes	tail
T936	2529-2536	SO:0000704	denotes	genetic
T937	2553-2563	GO:0007596	denotes	thrombotic
T2948	2634-2648	UBERON:0004535	denotes	cardiovascular
T2949	2683-2690	SO:0000704	denotes	genetic
T2950	2779-2784	NCBITaxon:9606	denotes	human
T2951	2798-2806	UBERON:0010210	denotes	Thrombus
T2952	2798-2816	GO:0007596	denotes	Thrombus formation
T2953	2970-2980	UBERON:0002349	denotes	myocardial
T2954	3023-3031	UBERON:0001637	denotes	arterial
T2955	3043-3051	UBERON:0001637	denotes	Arterial
T2956	3056-3062	UBERON:0001638	denotes	venous
T2957	3063-3073	GO:0007596	denotes	thrombosis
T2958	3127-3134	SO:0000704	denotes	genetic
T2959	3199-3210	GO:0050817	denotes	coagulation
T2960	3220-3232	GO:0042730	denotes	fibrinolytic
T2961	3242-3250	CL:0000233	denotes	platelet
T2962	3251-3258	GO:0009986	denotes	surface
T2963	3270-3295	CHEBI:12071	denotes	methylenetetrahydrofalate
T2964	3307-3318	UBERON:0001986	denotes	endothelial
T2965	3307-3340	PR:000011328	denotes	endothelial nitric oxide synthase
T2966	3319-3331	CHEBI:16480	denotes	nitric oxide
T2967	3390-3397	SO:0000704	denotes	genetic
T2968	3432-3442	GO:0007596	denotes	thrombosis
T2969	3513-3523	GO:0007596	denotes	thrombosis
T2970	3575-3585	GO:0007596	denotes	thrombosis
T2971	3678-3685	SO:0000704	denotes	genetic
T2972	3707-3717	GO:0007596	denotes	thrombotic
T2973	3757-3764	SO:0000704	denotes	genetic
T2974	3803-3812	CHEBI:36357	denotes	molecules
T2975	3835-3843	GO:0065007	denotes	regulate
T2976	3844-3852	UBERON:0010210	denotes	thrombus
T2977	3844-3862	GO:0007596	denotes	thrombus formation
T2978	3914-3924	GO:0007596	denotes	thrombotic
T2979	3963-3968	NCBITaxon:10088	denotes	mouse
T2980	4268-4276	UBERON:0001637	denotes	arterial
T2981	4369-4375	UBERON:0000055	denotes	vessel
T2982	4462-4472	GO:0007596	denotes	thrombosis
T2983	4491-4495	NCBITaxon:10088	denotes	mice
T2984	4539-4549	GO:0007596	denotes	thrombosis
T2985	4551-4555	UBERON:0010210	denotes	Clot
T2986	4551-4565	GO:0050817	denotes	Clot formation
T2987	4604-4614	GO:0007596	denotes	thrombosis
T2988	4625-4633	CL:0000233	denotes	platelet
T2989	4625-4645	GO:0070527	denotes	platelet aggregation
T2990	4647-4658	GO:0050817	denotes	coagulation
T2991	4664-4676	GO:0042730	denotes	fibrinolytic
T2992	4759-4767	GO:0065007	denotes	modulate
T2993	4944-4968	SO:0000771	denotes	quantitative trait locus
T2994	4970-4973	SO:0000771	denotes	QTL
T4488	7406-7415	CHEBI:35222	denotes	inhibitor
T22248	24140-24144	NCBITaxon:10088	denotes	mice
T22247	24099-24103	NCBITaxon:10088	denotes	mice
T22246	24027-24031	NCBITaxon:10088	denotes	mice
T22245	23954-23958	NCBITaxon:10088	denotes	mice
T22635	26400-26404	NCBITaxon:10088	denotes	mice
T22634	26359-26363	NCBITaxon:10088	denotes	mice
T22633	26287-26291	NCBITaxon:10088	denotes	mice
T22632	26214-26218	NCBITaxon:10088	denotes	mice
T22631	26165-26170	PR:000014702	denotes	PAI-1
T22630	26158-26164	UBERON:0001969	denotes	Plasma
T22629	26129-26136	CHEBI:59132	denotes	antigen
T22628	26123-26128	PR:000014702	denotes	PAI-1
T22627	26116-26122	UBERON:0001969	denotes	Plasma
T22626	26077-26082	PR:000014702	denotes	PAI-1
T21926	22810-22814	NCBITaxon:10088	denotes	mice
T21925	22769-22773	NCBITaxon:10088	denotes	mice
T21592	21432-21436	NCBITaxon:10088	denotes	mice
T21591	21348-21352	NCBITaxon:10088	denotes	mice
T21590	21308-21313	NCBITaxon:10088	denotes	mouse
T21589	21281-21285	UBERON:0002415	denotes	tail
T21588	21202-21206	UBERON:0002415	denotes	tail
T21587	21064-21068	NCBITaxon:10088	denotes	mice
T21586	20977-20981	NCBITaxon:10088	denotes	mice
T21585	20939-20950	CHEBI:51686	denotes	hematoxylin
T21584	20852-20863	CHEBI:51686	denotes	Hematoxylin
T21583	20787-20792	UBERON:0002415	denotes	Tails
T21582	20757-20761	UBERON:0002415	denotes	Tail
T20385	36661-36671	GO:0007596	denotes	thrombotic
T20384	36637-36644	SO:0000704	denotes	genetic
T20383	36458-36478	GO:0031012	denotes	extracellular matrix
T20382	36451-36457	UBERON:0000055	denotes	vessel
T20381	36422-36426	UBERON:0002415	denotes	tail
T20380	36410-36420	GO:0007596	denotes	thrombosis
T20379	36401-36409	UBERON:0001637	denotes	arterial
T20378	36357-36362	SO:0000704	denotes	genes
T20377	36323-36328	SO:0000704	denotes	genes
T20376	36247-36258	GO:0007599	denotes	haemostasis
T20375	36232-36242	GO:0007596	denotes	thrombosis
T20374	36208-36215	SO:0000704	denotes	genetic
T20373	36174-36178	NCBITaxon:10088	denotes	mice
T20759	14440-14444	NCBITaxon:10088	denotes	mice
T20758	14355-14359	NCBITaxon:10088	denotes	mice
T20757	14310-14318	UBERON:0001637	denotes	Arterial
T20756	14295-14299	NCBITaxon:10088	denotes	mice
T20755	14276-14280	NCBITaxon:10088	denotes	mice
T20754	14255-14262	UBERON:0005396	denotes	carotid
T20753	14220-14235	CHEBI:30808	denotes	ferric chloride
T20752	14111-14115	NCBITaxon:10088	denotes	mice
T20751	14073-14081	UBERON:0001637	denotes	Arterial
T18264	36071-36079	UBERON:0001637	denotes	arterial
T18263	36062-36070	GO:0065007	denotes	modulate
T18262	36046-36049	PR:000012867	denotes	Plg
T18261	36004-36009	SO:0000704	denotes	genes
T18260	35975-35978	SO:0000771	denotes	QTL
T18259	35945-35949	NCBITaxon:10088	denotes	mice
T18258	35890-35896	UBERON:0000055	denotes	vessel
T18257	35879-35885	UBERON:0000479	denotes	tissue
T18256	35853-35864	PR:000012867	denotes	plasminogen
T18255	35832-35836	UBERON:0002415	denotes	tail
T18254	35782-35787	CHEBI:30808	denotes	FeCl3
T18253	35756-35776	GO:0007596	denotes	thrombosis formation
T18252	35747-35755	UBERON:0001637	denotes	arterial
T18251	35726-35730	NCBITaxon:10088	denotes	mice
T18197	33637-33640	PR:000012826	denotes	uPA
T18196	33585-33590	UBERON:0000178	denotes	blood
T18195	33567-33571	NCBITaxon:10088	denotes	mice
T18194	33488-33492	NCBITaxon:10088	denotes	mice
T18193	33481-33484	PR:000012867	denotes	Plg
T18192	33446-33451	UBERON:0000178	denotes	Blood
T18191	33440-33444	NCBITaxon:10088	denotes	mice
T18190	33389-33394	UBERON:0000178	denotes	blood
T18189	33353-33357	NCBITaxon:10088	denotes	mice
T18188	33259-33263	UBERON:0002415	denotes	tail
T18187	33240-33244	NCBITaxon:10088	denotes	mice
T18186	33194-33199	UBERON:0000178	denotes	blood
T18185	33164-33175	SO:0000704	denotes	genetically
T18184	33140-33144	UBERON:0002415	denotes	tail
T18183	33088-33099	SO:0000704	denotes	genetically
T18182	32924-32928	NCBITaxon:10088	denotes	mice
T18181	32917-32920	PR:000012867	denotes	Plg
T18180	32878-32882	NCBITaxon:10088	denotes	mice
T18179	32871-32874	PR:000012867	denotes	Plg
T18178	32705-32709	UBERON:0002415	denotes	tail
T18177	32664-32668	NCBITaxon:10088	denotes	mice
T18176	32644-32648	NCBITaxon:10088	denotes	mice
T18175	32635-32640	PR:000014702	denotes	PAI-1
T18174	32627-32630	PR:000012826	denotes	uPA
T18173	32619-32622	PR:000012825	denotes	tPA
T18172	32550-32554	NCBITaxon:10088	denotes	mice
T18171	32529-32532	PR:000012867	denotes	Plg
T18170	32383-32387	NCBITaxon:10088	denotes	mice
T18169	32376-32379	PR:000012867	denotes	Plg
T18168	32325-32329	NCBITaxon:10088	denotes	mice
T18167	32318-32321	PR:000012826	denotes	uPA
T18166	32274-32279	PR:000014702	denotes	PAI-1
T18165	32240-32244	NCBITaxon:10088	denotes	mice
T18164	32233-32236	PR:000012867	denotes	Plg
T18163	32213-32217	NCBITaxon:10088	denotes	mice
T18162	32123-32127	NCBITaxon:10088	denotes	mice
T18161	32098-32102	UBERON:0002415	denotes	tail
T18160	32081-32089	UBERON:0010210	denotes	thrombus
T18159	32031-32042	GO:0050817	denotes	coagulation
T18158	32004-32011	SO:0000704	denotes	genetic
T18157	31981-31986	NCBITaxon:10088	denotes	mouse
T18156	31892-31910	GO:0007596	denotes	thrombus formation
T18155	31892-31900	UBERON:0010210	denotes	thrombus
T18154	31856-31864	CL:0000233	denotes	platelet
T18153	31826-31829	PR:000012826	denotes	uPA
T18152	31818-31821	PR:000012867	denotes	Plg
T18151	31799-31803	NCBITaxon:10088	denotes	mice
T18150	31792-31795	PR:000012826	denotes	uPA
T18149	31781-31784	PR:000012867	denotes	Plg
T18148	31676-31696	GO:0070527	denotes	platelet aggregation
T18147	31676-31684	CL:0000233	denotes	platelet
T18146	31621-31625	UBERON:0002415	denotes	tail
T18145	31570-31599	PR:000001664	denotes	protease-activated receptor-4
T18144	31544-31556	CHEBI:17089	denotes	glycoprotein
T18143	31535-31543	CL:0000233	denotes	platelet
T18142	31516-31524	CL:0000233	denotes	platelet
T18141	31461-31465	NCBITaxon:10088	denotes	Mice
T18140	31427-31445	GO:0007596	denotes	thrombus formation
T18139	31427-31435	UBERON:0010210	denotes	thrombus
T18138	31405-31412	SO:0000704	denotes	genetic
T18137	31307-31311	NCBITaxon:10088	denotes	mice
T18136	31293-31296	PR:000007303	denotes	FIX
T18135	31283-31288	PR:000007302	denotes	FVIII
T18134	31275-31279	UBERON:0002415	denotes	tail
T18133	31150-31161	GO:0050817	denotes	coagulation
T18132	31128-31132	SO:0000704	denotes	gene
T18131	31118-31122	NCBITaxon:10088	denotes	mice
T18130	31082-31089	CHEBI:59132	denotes	antigen
T18129	31067-31089	PR:000017364	denotes	von Willebrand antigen
T18128	31015-31019	NCBITaxon:10088	denotes	mice
T18127	30984-30988	NCBITaxon:10088	denotes	mice
T18126	30937-30941	NCBITaxon:10088	denotes	mice
T18125	30913-30924	GO:0050817	denotes	coagulation
T18124	30900-30908	CL:0000233	denotes	platelet
T18123	30886-30896	GO:0010467	denotes	expression
T18122	30835-30839	NCBITaxon:10088	denotes	mice
T18121	30786-30790	UBERON:0002415	denotes	tail
T18120	30762-30780	GO:0007596	denotes	thrombus formation
T18119	30762-30770	UBERON:0010210	denotes	thrombus
T18118	30721-30729	GO:0065007	denotes	modulate
T18117	30705-30709	UBERON:0010210	denotes	clot
T18116	30627-30631	NCBITaxon:10088	denotes	mice
T18115	30620-30623	PR:000014702	denotes	PAI
T18114	30593-30597	NCBITaxon:10088	denotes	mice
T18113	30586-30589	PR:000012867	denotes	Plg
T18112	30543-30561	GO:0007596	denotes	thrombus formation
T18111	30543-30551	UBERON:0010210	denotes	thrombus
T18110	30525-30528	PR:000012867	denotes	Plg
T18109	30495-30499	NCBITaxon:10088	denotes	mice
T18108	30439-30450	GO:0050817	denotes	coagulation
T18107	30416-30424	CL:0000233	denotes	platelet
T18106	30392-30396	NCBITaxon:10088	denotes	mice
T18105	30311-30316	UBERON:0000178	denotes	blood
T18104	30290-30294	NCBITaxon:10088	denotes	mice
T18103	30267-30275	UBERON:0010210	denotes	thrombus
T18102	30185-30189	NCBITaxon:10088	denotes	mice
T18101	30142-30150	UBERON:0001637	denotes	arterial
T18100	30130-30138	UBERON:0005396	denotes	carotids
T18099	29930-29935	UBERON:0000178	denotes	blood
T18098	29857-29861	NCBITaxon:10114	denotes	rats
T18097	29763-29767	NCBITaxon:10088	denotes	mice
T18096	29739-29743	NCBITaxon:10088	denotes	mice
T18250	35603-35606	PR:000012867	denotes	Plg
T18249	35575-35580	SO:0000704	denotes	genes
T18248	35479-35484	SO:0000704	denotes	genes
T18247	35468-35478	GO:0065007	denotes	regulatory
T18246	35424-35428	NCBITaxon:10088	denotes	mice
T18245	35405-35409	SO:0000704	denotes	gene
T18244	35390-35404	PR:000014706	denotes	α2-antiplasmin
T18243	35378-35382	SO:0000704	denotes	gene
T18242	35372-35377	PR:000014702	denotes	PAI-1
T18241	35340-35349	SO:0000028	denotes	base pair
T18240	35329-35334	SO:0000704	denotes	genes
T18239	35261-35267	GO:0031012	denotes	matrix
T18238	35231-35236	SO:0000704	denotes	genes
T18237	35216-35219	PR:000012867	denotes	Plg
T18236	35205-35208	SO:0000771	denotes	QTL
T18235	35179-35183	NCBITaxon:10088	denotes	mice
T18234	35050-35054	SO:0000704	denotes	gene
T18233	35046-35049	PR:000012867	denotes	Plg
T18232	35001-35005	NCBITaxon:10088	denotes	mice
T18231	34822-34825	PR:000012867	denotes	Plg
T18230	34774-34778	NCBITaxon:10088	denotes	mice
T18229	34754-34758	NCBITaxon:10088	denotes	mice
T18228	34715-34718	PR:000012867	denotes	Plg
T18227	34704-34708	NCBITaxon:10088	denotes	mice
T18226	34665-34669	SO:0000704	denotes	gene
T18225	34661-34664	PR:000012867	denotes	Plg
T18224	34655-34660	NCBITaxon:10088	denotes	mouse
T18223	34634-34641	SO:0001023	denotes	allelic
T18222	34614-34628	PR:000014706	denotes	α2-antiplasmin
T18221	34603-34608	PR:000014702	denotes	PAI-1
T18220	34598-34601	PR:000012867	denotes	Plg
T18219	34528-34532	NCBITaxon:10088	denotes	mice
T18218	34514-34518	NCBITaxon:10088	denotes	mice
T18217	34484-34488	NCBITaxon:10088	denotes	mice
T18216	34449-34457	UBERON:0001637	denotes	arterial
T18215	34317-34321	NCBITaxon:10088	denotes	mice
T18214	34214-34217	SO:0000771	denotes	QTL
T18213	34152-34166	PR:000014706	denotes	α2-antiplasmin
T18212	34141-34146	PR:000014702	denotes	PAI-1
T18211	34136-34139	PR:000012867	denotes	Plg
T18210	34126-34131	SO:0000704	denotes	genes
T18209	34082-34086	NCBITaxon:10088	denotes	mice
T18208	33971-33991	GO:0031012	denotes	extracellular matrix
T18207	33992-34000	GO:0019538	denotes	proteins
T18206	33945-33958	_FRAGMENT	denotes	metabolism of
T18205	33945-33967	GO:0032963	denotes	metabolism of collagen
T18204	33903-33907	NCBITaxon:10088	denotes	mice
T18203	33887-33891	UBERON:0002415	denotes	tail
T18202	33828-33832	UBERON:0002415	denotes	tail
T18201	33764-33768	UBERON:0002415	denotes	tail
T18200	33745-33750	UBERON:0000178	denotes	blood
T18199	33690-33695	UBERON:0000178	denotes	blood
T18198	33667-33671	NCBITaxon:10088	denotes	mice
T14872	26622-26630	UBERON:0001637	denotes	arterial
T14886	27388-27396	UBERON:0001637	denotes	arterial
T14885	27343-27348	SO:0000704	denotes	genes
T14884	27279-27287	UBERON:0001637	denotes	arterial
T14883	27249-27253	NCBITaxon:10088	denotes	mice
T14882	27184-27188	NCBITaxon:10088	denotes	mice
T14881	27134-27138	NCBITaxon:10088	denotes	mice
T14880	27110-27114	NCBITaxon:10088	denotes	mice
T14879	27008-27012	NCBITaxon:10088	denotes	mice
T14878	26906-26910	NCBITaxon:10088	denotes	mice
T14877	26822-26827	CHEBI:30808	denotes	FeCl3
T14876	26793-26801	UBERON:0001637	denotes	arterial
T14875	26654-26658	UBERON:0002415	denotes	tail
T14874	26631-26649	GO:0007596	denotes	thrombus formation
T14873	26631-26639	UBERON:0010210	denotes	thrombus
T14057	26061-26065	NCBITaxon:10088	denotes	mice
T14056	26026-26030	NCBITaxon:10088	denotes	mice
T14055	25943-25950	CHEBI:59132	denotes	antigen
T14054	25937-25942	PR:000014702	denotes	PAI-1
T14053	25858-25863	PR:000014702	denotes	PAI-1
T14052	25799-25803	NCBITaxon:10088	denotes	mice
T14051	25732-25737	PR:000014702	denotes	PAI-1
T14050	25508-25515	CHEBI:59132	denotes	antigen
T14049	25502-25507	PR:000014702	denotes	PAI-1
T14048	25484-25488	NCBITaxon:10088	denotes	mice
T14047	25456-25463	CHEBI:59132	denotes	antigen
T14046	25450-25455	PR:000014702	denotes	PAI-1
T14045	25201-25208	CHEBI:59132	denotes	antigen
T14044	25195-25200	PR:000014702	denotes	PAI-1
T14043	25189-25193	NCBITaxon:10088	denotes	mice
T14042	25165-25169	NCBITaxon:10088	denotes	mice
T12682	22076-22080	NCBITaxon:10088	denotes	mice
T12681	22052-22056	NCBITaxon:10088	denotes	mice
T12680	21880-21884	NCBITaxon:10088	denotes	mice
T12679	21711-21715	NCBITaxon:10088	denotes	mice
T12678	21622-21632	GO:0007596	denotes	thrombosis
T12677	21607-21617	GO:0007599	denotes	hemostasis
T12676	21550-21554	UBERON:0002415	denotes	tail
T12675	21514-21517	SO:0000771	denotes	QTL
T12674	21460-21464	UBERON:0002415	denotes	Tail
T11608	20724-20728	NCBITaxon:10088	denotes	mice
T11607	20682-20686	NCBITaxon:10088	denotes	mice
T11606	20656-20670	UBERON:0001013	denotes	adipose tissue
T11605	20645-20652	UBERON:0000055	denotes	vessels
T11604	20616-20620	NCBITaxon:10088	denotes	mice
T11603	20480-20484	UBERON:0002415	denotes	tail
T11602	20440-20458	GO:0007596	denotes	thrombus formation
T11601	20440-20448	UBERON:0010210	denotes	thrombus
T11600	20393-20401	CL:0000233	denotes	platelet
T11599	20305-20310	UBERON:0002415	denotes	tails
T11598	20241-20252	CHEBI:51686	denotes	Hematoxylin
T11597	20195-20211	UBERON:0001821	denotes	sebaceous glands
T11596	20179-20193	UBERON:0002073	denotes	hair follicles
T11595	20036-20047	CHEBI:51686	denotes	Hematoxylin
T11594	20013-20017	NCBITaxon:10088	denotes	mice
T11593	19988-19992	UBERON:0002415	denotes	tail
T11592	19860-19864	NCBITaxon:10088	denotes	mice
T11591	19847-19852	UBERON:0002415	denotes	tails
T11590	19813-19817	UBERON:0002415	denotes	Tail
T10894	18997-19003	UBERON:0001969	denotes	plasma
T10893	18991-18995	NCBITaxon:10088	denotes	mice
T10892	18974-18977	PR:000012867	denotes	Plg
T10891	18907-18911	NCBITaxon:10088	denotes	mice
T10890	18870-18880	GO:0005577	denotes	fibrinogen
T10889	18784-18788	NCBITaxon:10088	denotes	mice
T10888	18755-18759	NCBITaxon:10088	denotes	mice
T10887	18709-18723	PR:000014706	denotes	α2-anitplasmin
T10886	18689-18694	PR:000014702	denotes	PAI-1
T10885	18666-18678	GO:0042730	denotes	fibrinolytic
T10884	18647-18651	NCBITaxon:10088	denotes	mice
T10883	18631-18635	NCBITaxon:10088	denotes	mice
T10882	18587-18590	PR:000012867	denotes	Plg
T10881	18582-18586	NCBITaxon:10088	denotes	mice
T10880	18554-18559	PR:000014702	denotes	PAI-1
T10879	18546-18549	PR:000012867	denotes	Plg
T10912	19797-19802	NCBITaxon:10088	denotes	mouse
T10911	19782-19785	PR:000012867	denotes	Plg
T10910	19632-19636	NCBITaxon:10088	denotes	mice
T10909	19613-19619	UBERON:0001969	denotes	plasma
T10190	17988-17999	GO:0050817	denotes	coagulation
T10189	17932-17937	NCBITaxon:10088	denotes	mouse
T10188	17881-17885	NCBITaxon:10088	denotes	mice
T10187	17821-17835	GO:0050817	denotes	clot formation
T10186	17814-17825	UBERON:0010210	denotes	fibrin clot
T10185	17814-17820	CHEBI:5054	denotes	fibrin
T10184	17790-17798	CHEBI:9574	denotes	thrombin
T10183	17688-17692	PR:000007302	denotes	VIII
T10182	17681-17683	PR:000007303	denotes	IX
T10181	17677-17679	PR:000007295	denotes	XI
T10180	17664-17671	_FRAGMENT	denotes	Factors
T10179	17664-17675	PR:000007296	denotes	Factors XII
T10178	17650-17675	GO:0002542	denotes	activation of Factors XII
T10177	17581-17594	PR:000001940	denotes	tissue factor
T10176	17581-17587	UBERON:0000479	denotes	tissue
T10175	17567-17577	PR:000007301	denotes	Factor VII
T10174	17522-17551	GO:0007598	denotes	extrinsic coagulation pathway
T10173	17331-17342	GO:0050817	denotes	coagulation
T10172	17295-17299	NCBITaxon:10088	denotes	mice
T10171	17258-17275	GO:0007596	denotes	blood coagulation
T10170	17258-17263	UBERON:0000178	denotes	blood
T9319	16837-16841	NCBITaxon:10088	denotes	mice
T9318	16830-16833	PR:000012867	denotes	Plg
T9317	16758-16762	NCBITaxon:10088	denotes	mice
T9316	16749-16754	PR:000014702	denotes	PAI-1
T9315	16738-16741	PR:000012867	denotes	Plg
T9314	16690-16702	GO:0042730	denotes	fibrinolytic
T9313	16648-16652	NCBITaxon:10088	denotes	mice
T9312	16631-16635	NCBITaxon:10088	denotes	mice
T9311	16554-16558	NCBITaxon:10088	denotes	mice
T9310	16537-16541	NCBITaxon:10088	denotes	mice
T9309	16336-16344	UBERON:0010210	denotes	thrombus
T9308	15698-15718	GO:0070527	denotes	platelet aggregation
T9307	15698-15706	CL:0000233	denotes	platelet
T9306	15679-15683	NCBITaxon:10088	denotes	mice
T9305	15560-15568	CL:0000233	denotes	platelet
T9304	15548-15552	NCBITaxon:10088	denotes	mice
T9303	15517-15521	NCBITaxon:10088	denotes	mice
T9302	15497-15501	NCBITaxon:10088	denotes	mice
T9301	15488-15493	PR:000014702	denotes	PAI-1
T9300	15435-15439	NCBITaxon:10088	denotes	mice
T9299	15415-15419	NCBITaxon:10088	denotes	mice
T9298	15408-15411	PR:000012867	denotes	Plg
T9297	15328-15332	NCBITaxon:10088	denotes	mice
T9296	15243-15247	NCBITaxon:10088	denotes	mice
T9295	15211-15219	CL:0000233	denotes	platelet
T9294	15147-15167	GO:0070527	denotes	platelet aggregation
T9293	15147-15155	CL:0000233	denotes	platelet
T9292	15128-15132	NCBITaxon:10088	denotes	mice
T9291	15094-15098	NCBITaxon:10088	denotes	mice
T9290	15087-15090	PR:000014702	denotes	PAI
T9289	15076-15079	PR:000012867	denotes	Plg
T9288	15064-15074	GO:0007596	denotes	thrombosis
T9287	15055-15059	NCBITaxon:10088	denotes	mice
T9286	15037-15047	GO:0007599	denotes	hemostasis
T9285	15006-15010	NCBITaxon:10088	denotes	mice
T9284	14905-14909	NCBITaxon:10088	denotes	mice
T9283	14885-14889	NCBITaxon:10088	denotes	mice
T6801	11928-11933	NCBITaxon:10088	denotes	mouse
T6800	11816-11823	UBERON:0005396	denotes	carotid
T6799	11646-11650	UBERON:0002415	denotes	tail
T6798	11483-11491	UBERON:0005396	denotes	carotids
T6797	11466-11471	UBERON:0002415	denotes	tails
T6351	11370-11380	GO:0005577	denotes	fibrinogen
T6350	11364-11369	NCBITaxon:10088	denotes	mouse
T6349	11338-11348	GO:0042571	denotes	antibodies
T6348	11302-11312	GO:0005577	denotes	fibrinogen
T6347	11248-11256	GO:0042571	denotes	antibody
T6346	11242-11247	NCBITaxon:10088	denotes	mouse
T5281	9597-9601	NCBITaxon:10088	denotes	mice
T5280	9477-9482	UBERON:0000178	denotes	Blood
T5738	10063-10067	UBERON:0002415	denotes	tail
T5737	9896-9900	UBERON:0002415	denotes	tail
T5736	9853-9857	UBERON:0002415	denotes	tail
T5735	9837-9842	CHEBI:15377	denotes	water
T5734	9780-9784	UBERON:0002415	denotes	tail
T5733	9737-9745	CHEBI:6121	denotes	ketamine
T5732	9709-9713	NCBITaxon:10088	denotes	mice
T5731	9688-9692	UBERON:0002415	denotes	tail
T5279	9290-9295	UBERON:0000178	denotes	blood
T5278	9274-9280	UBERON:0001637	denotes	artery
T5277	9241-9249	CHEBI:75958	denotes	solution
T5276	9235-9240	CHEBI:30808	denotes	FeCl3
T5275	9154-9168	UBERON:0005396	denotes	carotid artery
T5274	9111-9119	CHEBI:75958	denotes	solution
T5273	9105-9110	CHEBI:30808	denotes	FeCl3
T5272	9004-9010	UBERON:0001637	denotes	artery
T5271	8877-8903	UBERON:0001536	denotes	left common carotid artery
T5270	8842-8850	UBERON:0005434	denotes	cervical
T5269	8793-8801	CHEBI:6121	denotes	ketamine
T5268	8765-8769	NCBITaxon:10088	denotes	Mice
T5267	8729-8735	UBERON:0000055	denotes	vessel
T5266	8713-8718	CHEBI:30808	denotes	FeCl3
T5265	8696-8711	CHEBI:30808	denotes	ferric chloride
T5264	8678-8692	UBERON:0005396	denotes	carotid artery
T5263	8650-8670	GO:0007596	denotes	thrombosis formation
T4512	8571-8577	NCBITaxon:33208	denotes	Animal
T4511	8477-8483	NCBITaxon:33208	denotes	animal
T4510	8317-8320	GO:0007631	denotes	fed
T4509	8307-8311	NCBITaxon:10088	denotes	Mice
T4508	8289-8294	CHEBI:15377	denotes	water
T4507	8280-8284	CHEBI:33290	denotes	food
T4506	8158-8162	NCBITaxon:10088	denotes	Mice
T4505	8058-8062	NCBITaxon:10088	denotes	mice
T4504	8002-8006	NCBITaxon:10088	denotes	mice
T4503	7960-7963	UBERON:0001690	denotes	ear
T4502	7876-7879	PR:000012867	denotes	Plg
T4501	7868-7871	PR:000012867	denotes	Plg
T4500	7860-7863	PR:000012867	denotes	Plg
T4499	7802-7805	PR:000012867	denotes	Plg
T4498	7783-7792	GO:0000003	denotes	reproduce
T4497	7771-7775	NCBITaxon:10088	denotes	mice
T4496	7764-7767	PR:000012867	denotes	Plg
T4495	7754-7758	NCBITaxon:10088	denotes	mice
T4494	7675-7679	NCBITaxon:10088	denotes	mice
T4493	7567-7571	NCBITaxon:10088	denotes	mice
T4492	7560-7563	PR:000012867	denotes	Plg
T4491	7457-7461	NCBITaxon:10088	denotes	mice
T4490	7432-7437	PR:000014702	denotes	PAI-1
T4489	7426-7430	NCBITaxon:10088	denotes	mice
T4487	7391-7394	_FRAGMENT	denotes	Plg
T4486	7396-7415	PR:000014702	denotes	activator inhibitor
T4485	7378-7389	_FRAGMENT	denotes	plasminogen
T4484	7364-7368	SO:0000704	denotes	gene
T4483	7290-7294	NCBITaxon:10088	denotes	Mice
T3017	6878-6888	GO:0007596	denotes	thrombotic
T3016	6856-6860	NCBITaxon:10088	denotes	mice
T3015	6767-6779	GO:0042730	denotes	fibrinolysis
T3014	6751-6762	GO:0050817	denotes	coagulation
T3013	6714-6718	UBERON:0002415	denotes	tail
T3012	6675-6690	CHEBI:30808	denotes	ferric chloride
T3011	6646-6656	GO:0007596	denotes	thrombotic
T3010	6634-6638	NCBITaxon:10088	denotes	mice
T3009	6548-6554	SO:0001026	denotes	genome
T3008	6504-6507	SO:0000771	denotes	QTL
T3007	6439-6445	UBERON:0001969	denotes	plasma
T3006	6421-6428	CHEBI:15889	denotes	sterols
T3005	6304-6307	SO:0000771	denotes	QTL
T3004	6228-6231	SO:0000771	denotes	QTL
T3003	6199-6202	SO:0000771	denotes	QTL
T3002	6131-6137	SO:0001026	denotes	genome
T3001	6115-6118	SO:0000771	denotes	QTL
T3000	6093-6097	NCBITaxon:10088	denotes	mice
T2999	6028-6031	SO:0000771	denotes	QTL
T2998	5912-5916	NCBITaxon:10088	denotes	mice
T2997	5760-5775	SO:0001645	denotes	Genetic markers
T2996	5754-5758	NCBITaxon:10088	denotes	mice
T2995	5568-5569	PR:000014702	denotes	A
T3025	7268-7278	GO:0007596	denotes	thrombosis
T3024	7252-7263	GO:0007599	denotes	haemostasis
T3023	7197-7204	SO:0000704	denotes	genetic
T3022	7140-7143	SO:0000771	denotes	QTL
T3021	7030-7038	UBERON:0001637	denotes	arterial
T3020	6929-6949	GO:0070527	denotes	platelet aggregation
T3019	6929-6937	CL:0000233	denotes	platelet
T3018	6914-6925	GO:0050817	denotes	coagulation
T6345	11162-11176	PR:000014706	denotes	α2-antiplasmin
T6344	11156-11161	NCBITaxon:10088	denotes	mouse
T6343	11121-11125	NCBITaxon:10088	denotes	mice
T6342	11107-11110	PR:000012867	denotes	Plg
T6341	11098-11103	PR:000014702	denotes	PAI-1
T6340	11086-11092	UBERON:0001969	denotes	plasma
T6339	11018-11024	CHEBI:5054	denotes	fibrin
T6338	10982-10994	GO:0042730	denotes	fibrinolytic
T6337	10951-10962	CHEBI:75050	denotes	chromogenic
T6336	10925-10928	PR:000012867	denotes	Plg
T6335	10865-10870	PR:000014702	denotes	PAI-1
T6334	10859-10864	NCBITaxon:10088	denotes	mouse
T6333	10846-10854	GO:0042571	denotes	antibody
T6332	10802-10807	PR:000014702	denotes	PAI-1
T6331	10796-10801	NCBITaxon:10088	denotes	mouse
T6330	10785-10790	NCBITaxon:9940	denotes	sheep
T6329	10728-10735	CHEBI:59132	denotes	antigen
T6328	10722-10727	PR:000014702	denotes	PAI-1
T6327	10644-10649	PR:000014702	denotes	PAI-1
T6326	10600-10611	GO:0050817	denotes	Coagulation
T6325	10448-10455	CHEBI:33893	denotes	reagent
T6324	10418-10423	UBERON:0000178	denotes	blood
T6323	10359-10366	UBERON:0001697	denotes	orbital
T6322	10324-10334	CHEBI:6015	denotes	Isoflurane
T6321	10296-10300	NCBITaxon:10088	denotes	Mice
T6320	10283-10288	PR:000014702	denotes	PAI-1
T6319	10266-10278	GO:0042730	denotes	fibrinolytic
T6318	10254-10264	GO:0005577	denotes	fibrinogen
T6317	10238-10252	PR:000014706	denotes	α2-antiplasmin
T6316	10233-10236	PR:000012867	denotes	Plg
T6315	10220-10231	GO:0050817	denotes	Coagulation
T7152	12343-12347	NCBITaxon:10088	denotes	mice
T7151	12173-12177	NCBITaxon:10088	denotes	mice
T7150	12164-12169	PR:000014702	denotes	PAI-1
T7149	12077-12080	PR:000012867	denotes	Plg
T7148	12041-12045	NCBITaxon:10088	denotes	mice
T8002	14057-14061	NCBITaxon:10088	denotes	mice
T8001	14032-14036	NCBITaxon:10088	denotes	mice
T8000	13952-13956	NCBITaxon:10088	denotes	mice
T7999	13885-13893	UBERON:0010210	denotes	thrombus
T7998	13830-13834	NCBITaxon:10088	denotes	mice
T7997	13813-13817	NCBITaxon:10088	denotes	mice
T7996	13674-13682	UBERON:0005396	denotes	carotids
T7995	13462-13467	UBERON:0000178	denotes	blood
T7994	13453-13457	NCBITaxon:10088	denotes	mice
T7993	13419-13423	NCBITaxon:10088	denotes	mice
T7992	13329-13334	CHEBI:30808	denotes	FeCl3
T7991	13312-13317	UBERON:0000178	denotes	blood
T7990	13100-13104	NCBITaxon:10088	denotes	mice
T7989	13039-13043	NCBITaxon:10088	denotes	mice
T7988	13004-13009	CHEBI:30808	denotes	FeCl3
T7987	12985-12989	NCBITaxon:10088	denotes	mice
T7986	12948-12952	NCBITaxon:10088	denotes	mice
T7985	12900-12904	NCBITaxon:10088	denotes	mice
T7984	12839-12857	GO:0007599	denotes	thrombus occlusion
T7983	12839-12847	UBERON:0010210	denotes	thrombus
T7982	12830-12838	UBERON:0001637	denotes	arterial
T7981	12772-12777	NCBITaxon:10088	denotes	mouse
T7980	12745-12753	UBERON:0010210	denotes	thrombus
T7979	12695-12705	GO:0007596	denotes	thrombosis
T7978	12686-12694	UBERON:0001637	denotes	arterial
T7977	12631-12645	UBERON:0005396	denotes	cartoid artery
T7976	12625-12630	CHEBI:30808	denotes	FeCl3
T7975	12616-12620	NCBITaxon:10088	denotes	mice
T7974	12583-12601	GO:0007596	denotes	thrombus formation
T7973	12583-12591	UBERON:0010210	denotes	thrombus
T7972	12574-12582	UBERON:0001637	denotes	arterial
T9326	17227-17230	PR:000012867	denotes	Plg
T9325	17209-17219	GO:0065007	denotes	regulation
T9324	17081-17086	PR:000014702	denotes	PAI-1
T9323	17002-17005	PR:000012867	denotes	Plg
T9322	16985-16989	NCBITaxon:10088	denotes	mice
T9321	16883-16887	NCBITaxon:10088	denotes	mice
T9320	16874-16879	PR:000014702	denotes	PAI-1
T10908	19592-19596	NCBITaxon:10088	denotes	mice
T10907	19572-19578	UBERON:0001969	denotes	plasma
T10906	19565-19568	PR:000012867	denotes	Plg
T10905	19520-19526	UBERON:0001969	denotes	plasma
T10904	19452-19456	NCBITaxon:10088	denotes	mice
T10903	19431-19435	NCBITaxon:10088	denotes	mice
T10902	19346-19350	NCBITaxon:10088	denotes	mice
T10901	19304-19310	UBERON:0001969	denotes	plasma
T10900	19281-19289	MOP:0000569	denotes	reducing
T10899	19266-19269	CHEBI:8984	denotes	SDS
T10898	19171-19174	PR:000012867	denotes	Plg
T10897	19086-19093	MOP:0000569	denotes	reduced
T10896	19073-19080	MOP:0000569	denotes	reduced
T10895	19028-19032	NCBITaxon:10088	denotes	mice
T12692	23331-23335	NCBITaxon:10088	denotes	mice
T12691	23283-23287	NCBITaxon:10088	denotes	mice
T12690	23158-23162	NCBITaxon:10088	denotes	mice
T12689	23130-23134	NCBITaxon:10088	denotes	mice
T12688	23099-23103	NCBITaxon:10088	denotes	mice
T12687	22587-22591	NCBITaxon:10088	denotes	mice
T12686	22525-22529	NCBITaxon:10088	denotes	mice
T12685	22410-22414	NCBITaxon:10088	denotes	mice
T12684	22264-22268	NCBITaxon:10088	denotes	mice
T12683	22218-22222	NCBITaxon:10088	denotes	mice
T14041	25030-25034	NCBITaxon:10088	denotes	mice
T14040	24967-24981	PR:000014706	denotes	α2-antiplasmin
T14039	24961-24965	NCBITaxon:10088	denotes	mice
T14038	24871-24883	GO:0042730	denotes	Fibrinolytic
T14037	24865-24869	NCBITaxon:10088	denotes	mice
T14036	24824-24831	CHEBI:59132	denotes	antigen
T14035	24820-24823	PR:000012867	denotes	Plg
T14034	24780-24784	NCBITaxon:10088	denotes	mice
T14033	24685-24692	CHEBI:59132	denotes	antigen
T14032	24681-24684	PR:000012867	denotes	Plg
T14031	24671-24675	NCBITaxon:10088	denotes	mice
T14030	24655-24659	NCBITaxon:10088	denotes	mice
T14029	24624-24634	GO:0005577	denotes	fibrinogen
T14028	24605-24610	PR:000014702	denotes	PAI-1
T14027	24589-24603	PR:000014706	denotes	α2-antiplasmin
T14026	24566-24578	GO:0042730	denotes	fibrinolytic
T14025	24557-24564	CHEBI:59132	denotes	antigen
T14024	24553-24556	PR:000012867	denotes	Plg
T14023	24534-24538	NCBITaxon:10088	denotes	mice
T14022	24467-24481	PR:000014706	denotes	α2-antiplasmin
T14021	24451-24456	PR:000014702	denotes	PAI-1
T14020	24411-24414	PR:000012867	denotes	Plg
T14019	24372-24379	CHEBI:59132	denotes	antigen
T14018	24366-24371	PR:000014702	denotes	PAI-1
T18095	29693-29702	GO:0007599	denotes	occlusion
T18094	29670-29678	_FRAGMENT	denotes	thrombus
T18093	29670-29688	GO:0007596	denotes	thrombus formation
T18092	29670-29678	UBERON:0010210	denotes	thrombus
T18091	29653-29658	CHEBI:30808	denotes	FeCl3
T18090	29633-29638	CHEBI:30808	denotes	FeCl3
T18089	29612-29626	UBERON:0005396	denotes	carotid artery
T18088	29497-29512	CHEBI:52217	denotes	pharmacological
T18087	29485-29492	SO:0000704	denotes	genetic
T18086	29449-29453	NCBITaxon:10088	denotes	mice
T18085	29435-29445	GO:0007596	denotes	thrombosis
T18084	29392-29397	CHEBI:30808	denotes	FeCl3
T18083	29232-29240	UBERON:0001637	denotes	Arterial
T18082	29093-29097	NCBITaxon:10088	denotes	mice
T18081	29012-29019	CHEBI:59132	denotes	antigen
T18080	29006-29011	PR:000014702	denotes	PAI-1
T18079	28839-28843	NCBITaxon:10088	denotes	Mice
T18078	28764-28769	SO:0000704	denotes	genes
T18077	28684-28692	CL:0000233	denotes	platelet
T18076	28669-28680	GO:0050817	denotes	coagulation
T18075	28543-28553	GO:0007596	denotes	thrombotic
T18074	28487-28495	CL:0000233	denotes	platelet
T18073	28467-28471	NCBITaxon:10088	denotes	mice
T18072	28412-28424	GO:0042730	denotes	fibrinolytic
T18071	28387-28390	PR:000012867	denotes	Plg
T18070	28375-28379	NCBITaxon:10088	denotes	mice
T18069	28361-28365	SO:0000704	denotes	gene
T18068	28273-28283	GO:0007596	denotes	thrombotic
T18067	28197-28201	UBERON:0002415	denotes	tail
T18066	28172-28180	UBERON:0001637	denotes	Arterial
T18065	28153-28159	UBERON:0000055	denotes	vessel
T18064	27998-28002	NCBITaxon:10088	denotes	mice
T18063	27929-27939	GO:0007596	denotes	thrombotic
T20561	5003-5007	NCBITaxon:10088	denotes	mice
T21131	16284-16288	NCBITaxon:10088	denotes	mice
T21130	16243-16247	NCBITaxon:10088	denotes	mice
T21129	16064-16069	PR:000014702	denotes	PAI-1
T21128	15996-15999	PR:000012867	denotes	Plg
T21127	15834-15838	NCBITaxon:10088	denotes	mice
T21126	15825-15830	PR:000014702	denotes	PAI-1
T21125	15814-15817	PR:000012867	denotes	Plg
T22988	27703-27707	NCBITaxon:10088	denotes	mice
T22987	27662-27666	NCBITaxon:10088	denotes	mice
T22986	27590-27594	NCBITaxon:10088	denotes	mice
T22985	27516-27520	NCBITaxon:10088	denotes	mice
T22984	27423-27431	UBERON:0001637	denotes	Arterial
T23137	18128-18133	NCBITaxon:10088	denotes	mouse
T23136	18077-18088	PR:000012867	denotes	Plasminogen
T23135	18061-18072	GO:0050817	denotes	Coagulation
T9282	14802-14807	NCBITaxon:10088	denotes	mouse
T9281	14664-14668	UBERON:0002415	denotes	tail
T9280	14621-14625	UBERON:0002415	denotes	tail
T9279	14564-14574	GO:0007599	denotes	hemostatic
T9278	14524-14528	NCBITaxon:10088	denotes	mice
T888	0-7	SO:0000704	denotes	Genetic
T889	42-52	GO:0007599	denotes	hemostasis
T890	57-67	GO:0007596	denotes	thrombosis
T891	89-99	GO:0007596	denotes	Thrombosis
T892	142-156	UBERON:0004535	denotes	cardiovascular
T893	245-250	NCBITaxon:10088	denotes	mouse
R1201	T4486	T4485	_lexicallyChainedTo	activator inhibitor,plasminogen
R1202	T4486	T4487	_lexicallyChainedTo	activator inhibitor,Plg
R3062	T10181	T10180	_lexicallyChainedTo	XI,Factors
R3063	T10182	T10180	_lexicallyChainedTo	IX,Factors
R3064	T10183	T10180	_lexicallyChainedTo	VIII,Factors
R4733	T18095	T18094	_lexicallyChainedTo	occlusion,thrombus
R4734	T18207	T18206	_lexicallyChainedTo	proteins,metabolism of

2_test

Id	Subject	Object	Predicate	Lexical cue
17022820-8127331-8600370	2598-2599	8127331	denotes	1
17022820-10332019-8600371	3162-3163	10332019	denotes	2
17022820-15051662-8600371	3162-3163	15051662	denotes	2
17022820-1456879-8600371	3162-3163	1456879	denotes	2
17022820-12970122-8600371	3162-3163	12970122	denotes	2
17022820-14615395-8600372	3444-3445	14615395	denotes	6
17022820-11001066-8600373	3446-3447	11001066	denotes	7
17022820-7752914-8600374	4166-4167	7752914	denotes	8
17022820-3841001-8600375	4264-4265	3841001	denotes	9
17022820-10793085-8600376	4420-4422	10793085	denotes	10
17022820-10700173-8600377	5632-5634	10700173	denotes	11
17022820-15998716-8600378	6398-6400	15998716	denotes	12
17022820-15031436-8600379	6416-6418	15031436	denotes	13
17022820-15031436-8600380	6430-6432	15031436	denotes	13
17022820-15031436-8600381	6466-6468	15031436	denotes	13
17022820-15741506-8600382	6469-6471	15741506	denotes	14
17022820-8254028-8600383	7453-7455	8254028	denotes	15
17022820-7586361-8600384	7612-7614	7586361	denotes	16
17022820-16150044-8600385	7971-7973	16150044	denotes	17
17022820-11425776-8600386	8744-8746	11425776	denotes	18
17022820-9529269-8600387	8747-8749	9529269	denotes	19
17022820-2498016-8600388	10717-10719	2498016	denotes	20
17022820-8123649-8600389	10775-10777	8123649	denotes	21
17022820-158845-8600390	10970-10972	158845	denotes	22
17022820-9157597-8600391	11038-11040	9157597	denotes	23
17022820-15031436-8600392	12537-12539	15031436	denotes	13
17022820-15351844-8600393	12660-12662	15351844	denotes	24
17022820-12676815-8600394	14003-14005	12676815	denotes	25
17022820-11714745-8600395	15169-15171	11714745	denotes	26
17022820-15351844-8600396	29528-29530	15351844	denotes	24
17022820-12676815-8600397	29834-29836	12676815	denotes	25
17022820-11714745-8600398	30398-30400	11714745	denotes	26
17022820-11791014-8600399	30538-30540	11791014	denotes	27
17022820-2124152-8600400	30957-30959	2124152	denotes	28
17022820-11341518-8600401	31104-31106	11341518	denotes	29
17022820-15213102-8600402	31561-31563	15213102	denotes	30
17022820-15304051-8600403	31602-31604	15304051	denotes	31
17022820-10235447-8600404	32571-32573	10235447	denotes	32
17022820-11788459-8600405	33346-33348	11788459	denotes	33
17022820-11991717-8600405	33346-33348	11991717	denotes	33
17022820-11368457-8600405	33346-33348	11368457	denotes	33
17022820-14612590-8600405	33346-33348	14612590	denotes	33
17022820-12171938-8600406	33645-33647	12171938	denotes	37
17022820-10703894-8600407	33660-33662	10703894	denotes	38
17022820-11709414-8600408	33663-33665	11709414	denotes	39
17022820-2081600-8600409	34710-34712	2081600	denotes	40

PMC:1617083 JSONTXT

Annnotations TAB JSON ListView MergeView

craft-sa-dev

craft-ca-core-ex-dev

craft-ca-core-dev

2_test

PMC:1617083 JSON TXT