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explain clinical heterogeneity in compound heterozygotes.\nPreviously, we generated a TTD mouse model (XPDR722W) that phenocopies the human syndrome [15,21]. Here we report the generation of additional mutant Xpd alleles that fail to support viability on their own but nevertheless "}

{"project":"craft-ca-core-dev","denotations":[{"id":"T458","span":{"begin":90,"end":95},"obj":"NCBITaxon:10088"},{"id":"T459","span":{"begin":103,"end":106},"obj":"PR:000007164"},{"id":"T460","span":{"begin":134,"end":139},"obj":"NCBITaxon:9606"},{"id":"T461","span":{"begin":209,"end":212},"obj":"PR:000007164"},{"id":"T462","span":{"begin":213,"end":220},"obj":"SO:0001023"}],"text":" explain clinical heterogeneity in compound heterozygotes.\nPreviously, we generated a TTD mouse model (XPDR722W) that phenocopies the human syndrome [15,21]. Here we report the generation of additional mutant Xpd alleles that fail to support viability on their own but nevertheless "}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T554","span":{"begin":90,"end":95},"obj":"NCBITaxon:10088"},{"id":"T555","span":{"begin":103,"end":106},"obj":"PR_EXT:000007164"},{"id":"T556","span":{"begin":134,"end":139},"obj":"NCBITaxon:9606"},{"id":"T557","span":{"begin":202,"end":208},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T558","span":{"begin":209,"end":212},"obj":"PR_EXT:000007164"},{"id":"T559","span":{"begin":213,"end":220},"obj":"SO_EXT:0001023"}],"text":" explain clinical heterogeneity in compound heterozygotes.\nPreviously, we generated a TTD mouse model (XPDR722W) that phenocopies the human syndrome [15,21]. Here we report the generation of additional mutant Xpd alleles that fail to support viability on their own but nevertheless "}

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