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PMC:1584416 / 4506-5425 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T1032 0-4 JJ denotes Many
T1033 9-18 NNS denotes mutations
T1034 5-8 NN denotes XPD
T1035 23-33 VBN denotes associated
T1036 19-22 VBP denotes are
T1037 34-38 IN denotes with
T1038 39-41 DT denotes an
T1039 60-69 NN denotes phenotype
T1040 42-51 JJ denotes exclusive
T1041 52-59 NN denotes disease
T1042 70-71 -LRB- denotes (
T1043 77-85 NN denotes XPDR722W
T1044 71-75 FW denotes e.g.
T1045 75-77 , denotes ,
T1046 86-90 IN denotes with
T1047 91-94 NN denotes TTD
T1048 95-98 CC denotes and
T1049 99-107 NN denotes XPDR683W
T1050 108-112 IN denotes with
T1051 113-115 NN denotes XP
T1052 115-116 -RRB- denotes )
T1053 117-120 CC denotes and
T1054 121-124 VBP denotes are
T1055 130-136 VBN denotes viewed
T1056 125-129 RB denotes thus
T1057 137-139 IN denotes as
T1058 140-149 JJ denotes causative
T1059 150-152 IN denotes of
T1060 153-156 DT denotes the
T1061 171-180 NNS denotes syndromes
T1062 157-170 VBG denotes corresponding
T1063 180-181 . denotes .
T1064 181-280 sentence denotes Alleles not associated exclusively with one disorder are considered “likely null” alleles [19,20].
T1065 182-189 NNS denotes Alleles
T1066 239-249 VBN denotes considered
T1067 190-193 RB denotes not
T1068 194-204 VBN denotes associated
T1069 205-216 RB denotes exclusively
T1070 217-221 IN denotes with
T1071 222-225 CD denotes one
T1072 226-234 NN denotes disorder
T1073 235-238 VBP denotes are
T1074 250-251 `` denotes
T1075 264-271 NNS denotes alleles
T1076 251-257 RB denotes likely
T1077 258-262 JJ denotes null
T1078 262-263 '' denotes
T1079 272-273 -LRB- denotes [
T1080 276-278 CD denotes 20
T1081 273-275 CD denotes 19
T1082 275-276 , denotes ,
T1083 278-279 -RRB- denotes ]
T1084 279-280 . denotes .
T1085 280-500 sentence denotes Some of these alleles fail to support viability in a haploid Schizosaccharomyces pombe yeast strain with a null mutation in the XPD homologue rad15 and are thus considered devoid of significant biological activity [19].
T1086 281-285 DT denotes Some
T1087 303-307 VBP denotes fail
T1088 286-288 IN denotes of
T1089 289-294 DT denotes these
T1090 295-302 NNS denotes alleles
T1091 308-310 TO denotes to
T1092 311-318 VB denotes support
T1093 319-328 NN denotes viability
T1094 329-331 IN denotes in
T1095 332-333 DT denotes a
T1096 374-380 NN denotes strain
T1097 334-341 JJ denotes haploid
T1098 342-361 NNP denotes Schizosaccharomyces
T1099 362-367 NNP denotes pombe
T1100 368-373 NN denotes yeast
T1101 381-385 IN denotes with
T1102 386-387 DT denotes a
T1103 393-401 NN denotes mutation
T1104 388-392 JJ denotes null
T1105 402-404 IN denotes in
T1106 405-408 DT denotes the
T1107 423-428 NN denotes rad15
T1108 409-412 NN denotes XPD
T1109 413-422 NN denotes homologue
T1110 429-432 CC denotes and
T1111 433-436 VBP denotes are
T1112 442-452 VBN denotes considered
T1113 437-441 RB denotes thus
T1114 453-459 JJ denotes devoid
T1115 460-462 IN denotes of
T1116 463-474 JJ denotes significant
T1117 486-494 NN denotes activity
T1118 475-485 JJ denotes biological
T1119 495-496 -LRB- denotes [
T1120 496-498 CD denotes 19
T1121 498-499 -RRB- denotes ]
T1122 499-500 . denotes .
T1123 500-638 sentence denotes This classification of alleles as either causative or null currently defines what we refer to as a “monoallelic” paradigm of XPD disease.
T1124 501-505 DT denotes This
T1125 506-520 NN denotes classification
T1126 570-577 VBZ denotes defines
T1127 521-523 IN denotes of
T1128 524-531 NNS denotes alleles
T1129 532-534 IN denotes as
T1130 535-541 CC denotes either
T1131 542-551 JJ denotes causative
T1132 552-554 CC denotes or
T1133 555-559 JJ denotes null
T1134 560-569 RB denotes currently
T1135 578-582 WP denotes what
T1136 586-591 VBP denotes refer
T1137 583-585 PRP denotes we
T1138 592-594 IN denotes to
T1139 595-597 IN denotes as
T1140 598-599 DT denotes a
T1141 614-622 NN denotes paradigm
T1142 600-601 `` denotes
T1143 601-612 JJ denotes monoallelic
T1144 612-613 '' denotes
T1145 623-625 IN denotes of
T1146 626-629 NN denotes XPD
T1147 630-637 NN denotes disease
T1148 637-638 . denotes .
T1149 638-919 sentence denotes However, the identification in recent years of XP complementation group D patients with atypical disease presentation, including symptoms of both XP and TTD [8], casts doubt on the ability of such a monoallelic paradigm to explain clinical heterogeneity in compound heterozygotes.
T1150 639-646 RB denotes However
T1151 801-806 VBZ denotes casts
T1152 646-648 , denotes ,
T1153 648-651 DT denotes the
T1154 652-666 NN denotes identification
T1155 667-669 IN denotes in
T1156 670-676 JJ denotes recent
T1157 677-682 NNS denotes years
T1158 683-685 IN denotes of
T1159 686-688 NN denotes XP
T1160 713-721 NNS denotes patients
T1161 689-704 NN denotes complementation
T1162 705-710 NN denotes group
T1163 711-712 NN denotes D
T1164 722-726 IN denotes with
T1165 727-735 JJ denotes atypical
T1166 744-756 NN denotes presentation
T1167 736-743 NN denotes disease
T1168 756-758 , denotes ,
T1169 758-767 VBG denotes including
T1170 768-776 NNS denotes symptoms
T1171 777-779 IN denotes of
T1172 780-784 CC denotes both
T1173 785-787 NN denotes XP
T1174 788-791 CC denotes and
T1175 792-795 NN denotes TTD
T1176 796-797 -LRB- denotes [
T1177 797-798 CD denotes 8
T1178 798-799 -RRB- denotes ]
T1179 799-801 , denotes ,
T1180 807-812 NN denotes doubt
T1181 813-815 IN denotes on
T1182 816-819 DT denotes the
T1183 820-827 NN denotes ability
T1184 828-830 IN denotes of
T1185 831-835 JJ denotes such
T1186 850-858 NN denotes paradigm
T1187 836-837 DT denotes a
T1188 838-849 JJ denotes monoallelic
T1189 859-861 TO denotes to
T1190 862-869 VB denotes explain
T1191 870-878 JJ denotes clinical
T1192 879-892 NN denotes heterogeneity
T1193 893-895 IN denotes in
T1194 896-904 NN denotes compound
T1195 905-918 NNS denotes heterozygotes
T1196 918-919 . denotes .
R687 T1032 T1033 amod Many,mutations
R689 T1034 T1033 compound XPD,mutations
R690 T1036 T1035 auxpass are,associated
R691 T1037 T1035 prep with,associated
R692 T1038 T1039 det an,phenotype
R693 T1039 T1037 pobj phenotype,with
R694 T1040 T1039 amod exclusive,phenotype
R695 T1041 T1039 compound disease,phenotype
R696 T1042 T1043 punct (,XPDR722W
R697 T1043 T1039 parataxis XPDR722W,phenotype
R698 T1044 T1043 advmod e.g.,XPDR722W
R699 T1045 T1043 punct ", ",XPDR722W
R700 T1046 T1043 prep with,XPDR722W
R701 T1047 T1046 pobj TTD,with
R702 T1048 T1043 cc and,XPDR722W
R703 T1049 T1043 conj XPDR683W,XPDR722W
R704 T1050 T1049 prep with,XPDR683W
R705 T1051 T1050 pobj XP,with
R706 T1052 T1043 punct ),XPDR722W
R707 T1053 T1035 cc and,associated
R708 T1054 T1055 auxpass are,viewed
R710 T1056 T1055 advmod thus,viewed
R711 T1057 T1055 prep as,viewed
R712 T1058 T1057 pobj causative,as
R713 T1059 T1058 prep of,causative
R714 T1060 T1061 det the,syndromes
R716 T1062 T1061 amod corresponding,syndromes
R717 T1063 T1035 punct .,associated
R718 T1065 T1066 nsubjpass Alleles,considered
R719 T1067 T1068 neg not,associated
R720 T1068 T1065 acl associated,Alleles
R721 T1069 T1068 advmod exclusively,associated
R722 T1070 T1068 prep with,associated
R723 T1071 T1072 nummod one,disorder
R724 T1072 T1070 pobj disorder,with
R725 T1073 T1066 auxpass are,considered
R726 T1074 T1075 punct “,alleles
R727 T1075 T1066 oprd alleles,considered
R728 T1076 T1077 advmod likely,null
R729 T1077 T1075 amod null,alleles
R730 T1078 T1075 punct ”,alleles
R731 T1079 T1080 punct [,20
R732 T1080 T1066 parataxis 20,considered
R733 T1081 T1080 nummod 19,20
R734 T1082 T1080 punct ",",20
R735 T1083 T1080 punct ],20
R736 T1084 T1066 punct .,considered
R737 T1086 T1087 nsubj Some,fail
R738 T1088 T1086 prep of,Some
R739 T1089 T1090 det these,alleles
R740 T1090 T1088 pobj alleles,of
R741 T1091 T1092 aux to,support
R742 T1092 T1087 xcomp support,fail
R743 T1093 T1092 dobj viability,support
R744 T1094 T1092 prep in,support
R745 T1095 T1096 det a,strain
R746 T1096 T1094 pobj strain,in
R747 T1097 T1096 amod haploid,strain
R748 T1098 T1096 compound Schizosaccharomyces,strain
R749 T1099 T1096 compound pombe,strain
R750 T1100 T1096 compound yeast,strain
R751 T1101 T1096 prep with,strain
R752 T1102 T1103 det a,mutation
R754 T1104 T1103 amod null,mutation
R755 T1105 T1103 prep in,mutation
R756 T1106 T1107 det the,rad15
R757 T1107 T1105 pobj rad15,in
R758 T1108 T1107 compound XPD,rad15
R759 T1109 T1107 compound homologue,rad15
R760 T1110 T1087 cc and,fail
R761 T1111 T1112 auxpass are,considered
R763 T1113 T1112 advmod thus,considered
R764 T1114 T1112 oprd devoid,considered
R765 T1115 T1114 prep of,devoid
R766 T1116 T1117 amod significant,activity
R768 T1118 T1117 amod biological,activity
R769 T1119 T1120 punct [,19
R770 T1120 T1112 parataxis 19,considered
R771 T1121 T1120 punct ],19
R772 T1122 T1087 punct .,fail
R773 T1124 T1125 det This,classification
R774 T1125 T1126 nsubj classification,defines
R775 T1127 T1125 prep of,classification
R776 T1128 T1127 pobj alleles,of
R777 T1129 T1125 prep as,classification
R778 T1130 T1131 preconj either,causative
R779 T1131 T1129 amod causative,as
R780 T1132 T1131 cc or,causative
R781 T1133 T1131 conj null,causative
R782 T1134 T1126 advmod currently,defines
R783 T1135 T1136 dep what,refer
R785 T1137 T1136 nsubj we,refer
R786 T1138 T1136 prep to,refer
R787 T1139 T1136 prep as,refer
R788 T1140 T1141 det a,paradigm
R789 T1141 T1139 pobj paradigm,as
R790 T1142 T1141 punct “,paradigm
R791 T1143 T1141 amod monoallelic,paradigm
R792 T1144 T1141 punct ”,paradigm
R793 T1145 T1141 prep of,paradigm
R794 T1146 T1147 compound XPD,disease
R795 T1147 T1145 pobj disease,of
R796 T1148 T1126 punct .,defines
R797 T1150 T1151 advmod However,casts
R798 T1152 T1151 punct ", ",casts
R799 T1153 T1154 det the,identification
R800 T1154 T1151 nsubj identification,casts
R801 T1155 T1154 prep in,identification
R802 T1156 T1157 amod recent,years
R803 T1157 T1155 pobj years,in
R804 T1158 T1157 prep of,years
R805 T1159 T1160 compound XP,patients
R806 T1160 T1158 pobj patients,of
R807 T1161 T1160 compound complementation,patients
R808 T1162 T1163 compound group,D
R809 T1163 T1160 compound D,patients
R810 T1164 T1160 prep with,patients
R811 T1165 T1166 amod atypical,presentation
R813 T1167 T1166 compound disease,presentation
R814 T1168 T1166 punct ", ",presentation
R815 T1169 T1166 prep including,presentation
R816 T1170 T1169 pobj symptoms,including
R817 T1171 T1170 prep of,symptoms
R818 T1172 T1173 preconj both,XP
R819 T1173 T1171 pobj XP,of
R820 T1174 T1173 cc and,XP
R821 T1175 T1173 conj TTD,XP
R822 T1176 T1177 punct [,8
R823 T1177 T1154 parataxis 8,identification
R824 T1178 T1177 punct ],8
R825 T1179 T1151 punct ", ",casts
R826 T1180 T1151 dobj doubt,casts
R827 T1181 T1151 prep on,casts
R828 T1182 T1183 det the,ability
R829 T1183 T1181 pobj ability,on
R830 T1184 T1183 prep of,ability
R831 T1185 T1186 amod such,paradigm
R832 T1186 T1184 pobj paradigm,of
R833 T1187 T1186 det a,paradigm
R834 T1188 T1186 amod monoallelic,paradigm
R835 T1189 T1190 aux to,explain
R836 T1190 T1183 acl explain,ability
R837 T1191 T1192 amod clinical,heterogeneity
R838 T1192 T1190 dobj heterogeneity,explain
R839 T1193 T1190 prep in,explain
R840 T1194 T1195 compound compound,heterozygotes
R841 T1195 T1193 pobj heterozygotes,in
R842 T1196 T1151 punct .,casts
R688 T1033 T1035 nsubjpass mutations,associated
R709 T1055 T1035 conj viewed,associated
R715 T1061 T1059 pobj syndromes,of
R753 T1103 T1101 pobj mutation,with
R762 T1112 T1087 conj considered,fail
R767 T1117 T1115 pobj activity,of
R784 T1136 T1126 ccomp refer,defines
R812 T1166 T1164 pobj presentation,with

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T444 5-8 PR:000007164 denotes XPD
T445 77-80 PR:000007164 denotes XPD
T446 99-102 PR:000007164 denotes XPD
T447 182-189 SO:0001023 denotes Alleles
T448 264-271 SO:0001023 denotes alleles
T449 295-302 SO:0001023 denotes alleles
T450 342-373 NCBITaxon:4896 denotes Schizosaccharomyces pombe yeast
T451 409-412 PR:000007164 denotes XPD
T452 413-422 SO:0000853 denotes homologue
T453 423-428 PR:P26659 denotes rad15
T454 524-531 SO:0001023 denotes alleles
T455 605-612 SO:0001023 denotes allelic
T456 626-629 PR:000007164 denotes XPD
T457 842-849 SO:0001023 denotes allelic

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T534 5-8 PR_EXT:000007164 denotes XPD
T535 9-18 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T536 77-80 PR_EXT:000007164 denotes XPD
T537 99-102 PR_EXT:000007164 denotes XPD
T538 182-189 SO_EXT:0001023 denotes Alleles
T539 258-262 SO_EXT:sequence_nullness denotes null
T540 264-271 SO_EXT:0001023 denotes alleles
T541 295-302 SO_EXT:0001023 denotes alleles
T542 342-373 NCBITaxon:4896 denotes Schizosaccharomyces pombe yeast
T543 388-392 SO_EXT:sequence_nullness denotes null
T544 393-401 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T545 409-412 PR_EXT:000007164 denotes XPD
T546 413-422 SO_EXT:0000853 denotes homologue
T547 423-428 PR_EXT:P26659 denotes rad15
T548 475-485 CHEBI_GO_EXT:biological_process_or_quality_or_role denotes biological
T549 524-531 SO_EXT:0001023 denotes alleles
T550 555-559 SO_EXT:sequence_nullness denotes null
T551 605-612 SO_EXT:0001023 denotes allelic
T552 626-629 PR_EXT:000007164 denotes XPD
T553 842-849 SO_EXT:0001023 denotes allelic

2_test

Id Subject Object Predicate Lexical cue
17020410-9238033-84795133 273-275 9238033 denotes 19
17020410-10447254-84795134 276-278 10447254 denotes 20
17020410-9238033-84795135 496-498 9238033 denotes 19
17020410-11709541-84795136 797-798 11709541 denotes 8
T56327 273-275 9238033 denotes 19
T63905 276-278 10447254 denotes 20
T81319 496-498 9238033 denotes 19
T90035 797-798 11709541 denotes 8