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PMC:1584416 / 33968-36162 JSONTXT

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Id Subject Object Predicate Lexical cue
T6364 23-33 NN denotes Derivation
T6365 34-37 CC denotes and
T6366 38-46 NN denotes analysis
T6367 47-49 IN denotes of
T6368 50-56 JJ denotes mutant
T6369 57-61 NNS denotes mice
T6370 61-62 . denotes .
T6371 62-152 sentence denotes Generation of XpdTTD (XPDR722W) and XpdTTD/KO mice has been described previously [21,22].
T6372 63-73 NN denotes Generation
T6373 123-132 VBN denotes described
T6374 74-76 IN denotes of
T6375 77-83 NN denotes XpdTTD
T6376 109-113 NNS denotes mice
T6377 84-85 -LRB- denotes (
T6378 85-93 NN denotes XPDR722W
T6379 93-94 -RRB- denotes )
T6380 95-98 CC denotes and
T6381 99-105 NN denotes XpdTTD
T6382 106-108 NN denotes KO
T6383 105-106 HYPH denotes /
T6384 114-117 VBZ denotes has
T6385 118-122 VBN denotes been
T6386 133-143 RB denotes previously
T6387 144-145 -LRB- denotes [
T6388 148-150 CD denotes 22
T6389 145-147 CD denotes 21
T6390 147-148 , denotes ,
T6391 150-151 -RRB- denotes ]
T6392 151-152 . denotes .
T6393 152-341 sentence denotes A detailed description of the generation of targeting constructs for Xpd†XPCS and Xpd †XP alleles carrying mutations encoding the G602D and R683W alterations will be provided upon request.
T6394 153-154 DT denotes A
T6395 164-175 NN denotes description
T6396 155-163 JJ denotes detailed
T6397 319-327 VBN denotes provided
T6398 176-178 IN denotes of
T6399 179-182 DT denotes the
T6400 183-193 NN denotes generation
T6401 194-196 IN denotes of
T6402 197-206 VBG denotes targeting
T6403 207-217 NNS denotes constructs
T6404 218-221 IN denotes for
T6405 222-230 NN denotes Xpd†XPCS
T6406 243-250 NNS denotes alleles
T6407 231-234 CC denotes and
T6408 235-242 NN denotes Xpd †XP
T6409 251-259 VBG denotes carrying
T6410 260-269 NNS denotes mutations
T6411 270-278 VBG denotes encoding
T6412 279-282 DT denotes the
T6413 299-310 NNS denotes alterations
T6414 283-288 NN denotes G602D
T6415 289-292 CC denotes and
T6416 293-298 NN denotes R683W
T6417 311-315 MD denotes will
T6418 316-318 VB denotes be
T6419 328-332 IN denotes upon
T6420 333-340 NN denotes request
T6421 340-341 . denotes .
T6422 341-436 sentence denotes Chimeric mice and mouse embryonic fibroblasts were generated according to standard procedures.
T6423 342-350 JJ denotes Chimeric
T6424 376-387 NNS denotes fibroblasts
T6425 351-355 NNS denotes mice
T6426 356-359 CC denotes and
T6427 360-365 NN denotes mouse
T6428 366-375 JJ denotes embryonic
T6429 393-402 VBN denotes generated
T6430 388-392 VBD denotes were
T6431 403-412 VBG denotes according
T6432 413-415 IN denotes to
T6433 416-424 JJ denotes standard
T6434 425-435 NNS denotes procedures
T6435 435-436 . denotes .
T6436 436-516 sentence denotes Haematoxylin and eosin staining was performed according to standard procedures.
T6437 437-449 NN denotes Haematoxylin
T6438 460-468 NN denotes staining
T6439 450-453 CC denotes and
T6440 454-459 NN denotes eosin
T6441 473-482 VBN denotes performed
T6442 469-472 VBD denotes was
T6443 483-492 VBG denotes according
T6444 493-495 IN denotes to
T6445 496-504 JJ denotes standard
T6446 505-515 NNS denotes procedures
T6447 515-516 . denotes .
T6448 516-572 sentence denotes Amino acid analysis was conducted as described in [21].
T6449 517-522 NN denotes Amino
T6450 523-527 NN denotes acid
T6451 528-536 NN denotes analysis
T6452 541-550 VBN denotes conducted
T6453 537-540 VBD denotes was
T6454 551-553 IN denotes as
T6455 554-563 VBN denotes described
T6456 564-566 IN denotes in
T6457 567-568 -LRB- denotes [
T6458 568-570 CD denotes 21
T6459 570-571 -RRB- denotes ]
T6460 571-572 . denotes .
T6461 572-669 sentence denotes Blood values were analysed using Animal Blood Counter Vet (ABX Diagnostix, Montpellier, France).
T6462 573-578 NN denotes Blood
T6463 579-585 NNS denotes values
T6464 591-599 VBN denotes analysed
T6465 586-590 VBD denotes were
T6466 600-605 VBG denotes using
T6467 606-612 NN denotes Animal
T6468 627-630 NN denotes Vet
T6469 613-618 NN denotes Blood
T6470 619-626 JJ denotes Counter
T6471 631-632 -LRB- denotes (
T6472 636-646 NNP denotes Diagnostix
T6473 632-635 NNP denotes ABX
T6474 646-648 , denotes ,
T6475 648-659 NNP denotes Montpellier
T6476 659-661 , denotes ,
T6477 661-667 NNP denotes France
T6478 667-668 -RRB- denotes )
T6479 668-669 . denotes .
T6480 669-764 sentence denotes Radiographs were taken, and relative bone mineral density was calculated as described in [15].
T6481 670-681 NNS denotes Radiographs
T6482 687-692 VBN denotes taken
T6483 682-686 VBD denotes were
T6484 692-694 , denotes ,
T6485 694-697 CC denotes and
T6486 698-706 JJ denotes relative
T6487 720-727 NN denotes density
T6488 707-711 NN denotes bone
T6489 712-719 NN denotes mineral
T6490 732-742 VBN denotes calculated
T6491 728-731 VBD denotes was
T6492 743-745 IN denotes as
T6493 746-755 VBN denotes described
T6494 756-758 IN denotes in
T6495 759-760 -LRB- denotes [
T6496 760-762 CD denotes 15
T6497 762-763 -RRB- denotes ]
T6498 763-764 . denotes .
T6499 764-855 sentence denotes Mice used in this study were in a 129Ola/C57BL6 mixed background unless noted differently.
T6500 765-769 NNS denotes Mice
T6501 789-793 VBD denotes were
T6502 770-774 VBN denotes used
T6503 775-777 IN denotes in
T6504 778-782 DT denotes this
T6505 783-788 NN denotes study
T6506 794-796 IN denotes in
T6507 797-798 DT denotes a
T6508 819-829 NN denotes background
T6509 799-805 NN denotes 129Ola
T6510 806-812 NN denotes C57BL6
T6511 805-806 HYPH denotes /
T6512 813-818 JJ denotes mixed
T6513 830-836 IN denotes unless
T6514 837-842 VBN denotes noted
T6515 843-854 RB denotes differently
T6516 854-855 . denotes .
T6517 855-1082 sentence denotes All experiments involving mice were judged and approved by the national committee for genetic identification of organisms and the animal ethical committee, and were conducted according to national and international guidelines.
T6518 856-859 DT denotes All
T6519 860-871 NNS denotes experiments
T6520 892-898 VBN denotes judged
T6521 872-881 VBG denotes involving
T6522 882-886 NNS denotes mice
T6523 887-891 VBD denotes were
T6524 899-902 CC denotes and
T6525 903-911 VBN denotes approved
T6526 912-914 IN denotes by
T6527 915-918 DT denotes the
T6528 928-937 NN denotes committee
T6529 919-927 JJ denotes national
T6530 938-941 IN denotes for
T6531 942-949 JJ denotes genetic
T6532 950-964 NN denotes identification
T6533 965-967 IN denotes of
T6534 968-977 NNS denotes organisms
T6535 978-981 CC denotes and
T6536 982-985 DT denotes the
T6537 1001-1010 NN denotes committee
T6538 986-992 NN denotes animal
T6539 993-1000 JJ denotes ethical
T6540 1010-1012 , denotes ,
T6541 1012-1015 CC denotes and
T6542 1016-1020 VBD denotes were
T6543 1021-1030 VBN denotes conducted
T6544 1031-1040 VBG denotes according
T6545 1041-1043 IN denotes to
T6546 1044-1052 JJ denotes national
T6547 1071-1081 NNS denotes guidelines
T6548 1053-1056 CC denotes and
T6549 1057-1070 JJ denotes international
T6550 1081-1082 . denotes .
T6587 1084-1086 NN denotes UV
T6588 1087-1098 NN denotes sensitivity
T6589 1098-1100 , denotes ,
T6590 1100-1102 NN denotes UV
T6591 1103-1106 NN denotes UDS
T6592 1102-1103 HYPH denotes -
T6593 1144-1152 NN denotes activity
T6594 1106-1108 , denotes ,
T6595 1108-1110 NN denotes UV
T6596 1111-1114 NN denotes RRS
T6597 1110-1111 HYPH denotes -
T6598 1114-1116 , denotes ,
T6599 1116-1119 CC denotes and
T6600 1120-1125 NN denotes TFIIH
T6601 1126-1134 NN denotes incision
T6602 1135-1143 NN denotes excision
T6603 1134-1135 HYPH denotes /
T6604 1152-1153 . denotes .
T6605 1153-1240 sentence denotes UV survival, UV-UDS, and UV-RRS assays were performed as described previously [21,30].
T6606 1154-1156 NN denotes UV
T6607 1157-1165 NN denotes survival
T6608 1186-1192 NNS denotes assays
T6609 1165-1167 , denotes ,
T6610 1167-1169 NN denotes UV
T6611 1170-1173 NN denotes UDS
T6612 1169-1170 HYPH denotes -
T6613 1173-1175 , denotes ,
T6614 1175-1178 CC denotes and
T6615 1179-1181 NN denotes UV
T6616 1182-1185 NN denotes RRS
T6617 1181-1182 HYPH denotes -
T6618 1198-1207 VBN denotes performed
T6619 1193-1197 VBD denotes were
T6620 1208-1210 IN denotes as
T6621 1211-1220 VBN denotes described
T6622 1221-1231 RB denotes previously
T6623 1232-1233 -LRB- denotes [
T6624 1236-1238 CD denotes 30
T6625 1233-1235 CD denotes 21
T6626 1235-1236 , denotes ,
T6627 1238-1239 -RRB- denotes ]
T6628 1239-1240 . denotes .
T6629 1240-1399 sentence denotes For UV-RRS, average values from the representative experiment containing two wt, three XpdTTD/TTD, two XpdTTD/XPCS, and one XpdTTD/XP cell line are presented.
T6630 1241-1244 IN denotes For
T6631 1389-1398 VBN denotes presented
T6632 1245-1247 NN denotes UV
T6633 1248-1251 NN denotes RRS
T6634 1247-1248 HYPH denotes -
T6635 1251-1253 , denotes ,
T6636 1253-1260 JJ denotes average
T6637 1261-1267 NNS denotes values
T6638 1268-1272 IN denotes from
T6639 1273-1276 DT denotes the
T6640 1292-1302 NN denotes experiment
T6641 1277-1291 JJ denotes representative
T6642 1303-1313 VBG denotes containing
T6643 1314-1317 CD denotes two
T6644 1318-1320 NN denotes wt
T6645 1380-1384 NN denotes line
T6646 1320-1322 , denotes ,
T6647 1322-1327 CD denotes three
T6648 1335-1338 NN denotes TTD
T6649 1328-1334 NN denotes XpdTTD
T6650 1334-1335 HYPH denotes /
T6651 1338-1340 , denotes ,
T6652 1340-1343 CD denotes two
T6653 1351-1355 NN denotes XPCS
T6654 1344-1350 NN denotes XpdTTD
T6655 1350-1351 HYPH denotes /
T6656 1355-1357 , denotes ,
T6657 1357-1360 CC denotes and
T6658 1361-1364 CD denotes one
T6659 1372-1374 NN denotes XP
T6660 1365-1371 NN denotes XpdTTD
T6661 1371-1372 HYPH denotes /
T6662 1375-1379 NN denotes cell
T6663 1385-1388 VBP denotes are
T6664 1398-1399 . denotes .
T6665 1399-1647 sentence denotes The ~48% UV-UDS value presented in this study for XpdTTD/TTD cells differs from our previously published data of 25% UV-UDS [21], possibly because of the high variability intrinsic to the assay or routine variations in the cell culture conditions.
T6666 1400-1403 DT denotes The
T6667 1416-1421 NN denotes value
T6668 1404-1405 SYM denotes ~
T6669 1405-1407 CD denotes 48
T6670 1407-1408 NN denotes %
T6671 1409-1411 NN denotes UV
T6672 1412-1415 NN denotes UDS
T6673 1411-1412 HYPH denotes -
T6674 1467-1474 VBZ denotes differs
T6675 1422-1431 VBN denotes presented
T6676 1432-1434 IN denotes in
T6677 1435-1439 DT denotes this
T6678 1440-1445 NN denotes study
T6679 1446-1449 IN denotes for
T6680 1450-1456 NN denotes XpdTTD
T6681 1457-1460 NN denotes TTD
T6682 1456-1457 HYPH denotes /
T6683 1461-1466 NNS denotes cells
T6684 1475-1479 IN denotes from
T6685 1480-1483 PRP$ denotes our
T6686 1505-1509 NNS denotes data
T6687 1484-1494 RB denotes previously
T6688 1495-1504 VBN denotes published
T6689 1510-1512 IN denotes of
T6690 1513-1515 CD denotes 25
T6691 1515-1516 NN denotes %
T6692 1520-1523 NN denotes UDS
T6693 1517-1519 NN denotes UV
T6694 1519-1520 HYPH denotes -
T6695 1524-1525 -LRB- denotes [
T6696 1525-1527 CD denotes 21
T6697 1527-1528 -RRB- denotes ]
T6698 1528-1530 , denotes ,
T6699 1530-1538 RB denotes possibly
T6700 1539-1546 IN denotes because
T6701 1547-1549 IN denotes of
T6702 1550-1553 DT denotes the
T6703 1559-1570 NN denotes variability
T6704 1554-1558 JJ denotes high
T6705 1571-1580 JJ denotes intrinsic
T6706 1581-1583 IN denotes to
T6707 1584-1587 DT denotes the
T6708 1588-1593 NN denotes assay
T6709 1594-1596 CC denotes or
T6710 1597-1604 JJ denotes routine
T6711 1605-1615 NNS denotes variations
T6712 1616-1618 IN denotes in
T6713 1619-1622 DT denotes the
T6714 1636-1646 NNS denotes conditions
T6715 1623-1627 NN denotes cell
T6716 1628-1635 NN denotes culture
T6717 1646-1647 . denotes .
T6718 1647-1762 sentence denotes For the incision/excision activity assay, recombinant TFIIH was prepared and assayed as described previously [27].
T6719 1648-1651 IN denotes For
T6720 1712-1720 VBN denotes prepared
T6721 1652-1655 DT denotes the
T6722 1683-1688 NN denotes assay
T6723 1656-1664 NN denotes incision
T6724 1665-1673 NN denotes excision
T6725 1664-1665 HYPH denotes /
T6726 1674-1682 NN denotes activity
T6727 1688-1690 , denotes ,
T6728 1690-1701 JJ denotes recombinant
T6729 1702-1707 NN denotes TFIIH
T6730 1708-1711 VBD denotes was
T6731 1721-1724 CC denotes and
T6732 1725-1732 VBN denotes assayed
T6733 1733-1735 IN denotes as
T6734 1736-1745 VBN denotes described
T6735 1746-1756 RB denotes previously
T6736 1757-1758 -LRB- denotes [
T6737 1758-1760 CD denotes 27
T6738 1760-1761 -RRB- denotes ]
T6739 1761-1762 . denotes .
T6809 1997-2194 sentence denotes Two or more cell lines per genotype (except for the XpdTTD/†XP cells, in which only one cell line was used in repeated experiments) were used, and experiments were repeated 2–6 times per genotype.
T6810 1998-2001 CD denotes Two
T6811 2015-2020 NNS denotes lines
T6812 2002-2004 CC denotes or
T6813 2005-2009 JJR denotes more
T6814 2010-2014 NN denotes cell
T6815 2135-2139 VBN denotes used
T6816 2021-2024 IN denotes per
T6817 2025-2033 NN denotes genotype
T6818 2034-2035 -LRB- denotes (
T6819 2035-2041 IN denotes except
T6820 2042-2045 IN denotes for
T6821 2046-2049 DT denotes the
T6822 2061-2066 NNS denotes cells
T6823 2050-2056 NN denotes XpdTTD
T6824 2057-2060 NN denotes †XP
T6825 2056-2057 HYPH denotes /
T6826 2066-2068 , denotes ,
T6827 2068-2070 IN denotes in
T6828 2100-2104 VBN denotes used
T6829 2071-2076 WDT denotes which
T6830 2077-2081 RB denotes only
T6831 2091-2095 NN denotes line
T6832 2082-2085 CD denotes one
T6833 2086-2090 NN denotes cell
T6834 2096-2099 VBD denotes was
T6835 2105-2107 IN denotes in
T6836 2108-2116 VBN denotes repeated
T6837 2117-2128 NNS denotes experiments
T6838 2128-2129 -RRB- denotes )
T6839 2130-2134 VBD denotes were
T6840 2139-2141 , denotes ,
T6841 2141-2144 CC denotes and
T6842 2145-2156 NNS denotes experiments
T6843 2162-2170 VBN denotes repeated
T6844 2157-2161 VBD denotes were
T6845 2171-2172 CD denotes 2
T6846 2173-2174 CD denotes 6
T6847 2172-2173 HYPH denotes –
T6848 2175-2180 NNS denotes times
T6849 2181-2184 IN denotes per
T6850 2185-2193 NN denotes genotype
T6851 2193-2194 . denotes .
T6770 1764-1775 JJ denotes Comparative
T6771 1776-1794 NN denotes immunofluorescence
T6772 1794-1795 . denotes .
T6773 1795-1997 sentence denotes Latex bead labelling and comparative immunofluorescence analysis of the p62 subunit of the TFIIH was performed as described previously [16,17] using primary mouse embryonic fibroblasts at passages 2–5.
T6774 1796-1801 NN denotes Latex
T6775 1807-1816 NN denotes labelling
T6776 1802-1806 NN denotes bead
T6777 1897-1906 VBN denotes performed
T6778 1817-1820 CC denotes and
T6779 1821-1832 JJ denotes comparative
T6780 1852-1860 NN denotes analysis
T6781 1833-1851 NN denotes immunofluorescence
T6782 1861-1863 IN denotes of
T6783 1864-1867 DT denotes the
T6784 1872-1879 NN denotes subunit
T6785 1868-1871 NN denotes p62
T6786 1880-1882 IN denotes of
T6787 1883-1886 DT denotes the
T6788 1887-1892 NN denotes TFIIH
T6789 1893-1896 VBD denotes was
T6790 1907-1909 IN denotes as
T6791 1910-1919 VBN denotes described
T6792 1920-1930 RB denotes previously
T6793 1931-1932 -LRB- denotes [
T6794 1935-1937 CD denotes 17
T6795 1932-1934 CD denotes 16
T6796 1934-1935 , denotes ,
T6797 1937-1938 -RRB- denotes ]
T6798 1939-1944 VBG denotes using
T6799 1945-1952 JJ denotes primary
T6800 1969-1980 NNS denotes fibroblasts
T6801 1953-1958 NN denotes mouse
T6802 1959-1968 JJ denotes embryonic
T6803 1981-1983 IN denotes at
T6804 1984-1992 NNS denotes passages
T6805 1993-1994 CD denotes 2
T6806 1994-1995 SYM denotes –
T6807 1995-1996 CD denotes 5
T6808 1996-1997 . denotes .
R4335 T6365 T6364 cc and,Derivation
R4336 T6366 T6364 conj analysis,Derivation
R4337 T6367 T6364 prep of,Derivation
R4338 T6368 T6369 amod mutant,mice
R4339 T6369 T6367 pobj mice,of
R4340 T6370 T6364 punct .,Derivation
R4341 T6372 T6373 nsubjpass Generation,described
R4342 T6374 T6372 prep of,Generation
R4343 T6375 T6376 nmod XpdTTD,mice
R4344 T6376 T6374 pobj mice,of
R4345 T6377 T6378 punct (,XPDR722W
R4346 T6378 T6375 parataxis XPDR722W,XpdTTD
R4347 T6379 T6378 punct ),XPDR722W
R4348 T6380 T6375 cc and,XpdTTD
R4349 T6381 T6382 compound XpdTTD,KO
R4350 T6382 T6375 conj KO,XpdTTD
R4351 T6383 T6382 punct /,KO
R4352 T6384 T6373 aux has,described
R4353 T6385 T6373 auxpass been,described
R4354 T6386 T6373 advmod previously,described
R4355 T6387 T6388 punct [,22
R4356 T6388 T6373 parataxis 22,described
R4357 T6389 T6388 nummod 21,22
R4358 T6390 T6388 punct ",",22
R4359 T6391 T6388 punct ],22
R4360 T6392 T6373 punct .,described
R4361 T6394 T6395 det A,description
R4362 T6395 T6397 nsubjpass description,provided
R4363 T6396 T6395 amod detailed,description
R4364 T6398 T6395 prep of,description
R4365 T6399 T6400 det the,generation
R4366 T6400 T6398 pobj generation,of
R4367 T6401 T6400 prep of,generation
R4368 T6402 T6403 amod targeting,constructs
R4369 T6403 T6401 pobj constructs,of
R4370 T6404 T6403 prep for,constructs
R4371 T6405 T6406 nmod Xpd†XPCS,alleles
R4372 T6406 T6404 pobj alleles,for
R4373 T6407 T6405 cc and,Xpd†XPCS
R4374 T6408 T6405 conj Xpd †XP,Xpd†XPCS
R4375 T6409 T6406 acl carrying,alleles
R4376 T6410 T6409 dobj mutations,carrying
R4377 T6411 T6410 acl encoding,mutations
R4378 T6412 T6413 det the,alterations
R4379 T6413 T6411 dobj alterations,encoding
R4380 T6414 T6413 nmod G602D,alterations
R4381 T6415 T6414 cc and,G602D
R4382 T6416 T6414 conj R683W,G602D
R4383 T6417 T6397 aux will,provided
R4384 T6418 T6397 auxpass be,provided
R4385 T6419 T6397 prep upon,provided
R4386 T6420 T6419 pobj request,upon
R4387 T6421 T6397 punct .,provided
R4388 T6423 T6424 amod Chimeric,fibroblasts
R4389 T6424 T6429 nsubjpass fibroblasts,generated
R4390 T6425 T6424 nmod mice,fibroblasts
R4391 T6426 T6425 cc and,mice
R4392 T6427 T6428 npadvmod mouse,embryonic
R4393 T6428 T6425 conj embryonic,mice
R4394 T6430 T6429 auxpass were,generated
R4395 T6431 T6429 prep according,generated
R4396 T6432 T6431 prep to,according
R4397 T6433 T6434 amod standard,procedures
R4398 T6434 T6432 pobj procedures,to
R4399 T6435 T6429 punct .,generated
R4400 T6437 T6438 nmod Haematoxylin,staining
R4401 T6438 T6441 nsubjpass staining,performed
R4402 T6439 T6437 cc and,Haematoxylin
R4403 T6440 T6437 conj eosin,Haematoxylin
R4404 T6442 T6441 auxpass was,performed
R4405 T6443 T6441 prep according,performed
R4406 T6444 T6443 prep to,according
R4407 T6445 T6446 amod standard,procedures
R4408 T6446 T6444 pobj procedures,to
R4409 T6447 T6441 punct .,performed
R4410 T6449 T6450 compound Amino,acid
R4411 T6450 T6451 compound acid,analysis
R4412 T6451 T6452 nsubjpass analysis,conducted
R4413 T6453 T6452 auxpass was,conducted
R4414 T6454 T6455 mark as,described
R4415 T6455 T6452 advcl described,conducted
R4416 T6456 T6455 prep in,described
R4417 T6457 T6456 punct [,in
R4418 T6458 T6456 pobj 21,in
R4419 T6459 T6452 punct ],conducted
R4420 T6460 T6452 punct .,conducted
R4421 T6462 T6463 compound Blood,values
R4422 T6463 T6464 nsubjpass values,analysed
R4423 T6465 T6464 auxpass were,analysed
R4424 T6466 T6464 advcl using,analysed
R4425 T6467 T6468 nmod Animal,Vet
R4426 T6468 T6466 dobj Vet,using
R4427 T6469 T6468 nmod Blood,Vet
R4428 T6470 T6468 amod Counter,Vet
R4429 T6471 T6472 punct (,Diagnostix
R4430 T6472 T6468 parataxis Diagnostix,Vet
R4431 T6473 T6472 compound ABX,Diagnostix
R4432 T6474 T6472 punct ", ",Diagnostix
R4433 T6475 T6472 npadvmod Montpellier,Diagnostix
R4434 T6476 T6472 punct ", ",Diagnostix
R4435 T6477 T6472 npadvmod France,Diagnostix
R4436 T6478 T6472 punct ),Diagnostix
R4437 T6479 T6464 punct .,analysed
R4438 T6481 T6482 nsubjpass Radiographs,taken
R4439 T6483 T6482 auxpass were,taken
R4440 T6484 T6482 punct ", ",taken
R4441 T6485 T6482 cc and,taken
R4442 T6486 T6487 amod relative,density
R4443 T6487 T6490 nsubjpass density,calculated
R4444 T6488 T6489 compound bone,mineral
R4445 T6489 T6487 compound mineral,density
R4446 T6490 T6482 conj calculated,taken
R4447 T6491 T6490 auxpass was,calculated
R4448 T6492 T6493 mark as,described
R4449 T6493 T6490 advcl described,calculated
R4450 T6494 T6493 prep in,described
R4451 T6495 T6494 punct [,in
R4452 T6496 T6494 pobj 15,in
R4453 T6497 T6490 punct ],calculated
R4454 T6498 T6490 punct .,calculated
R4455 T6500 T6501 nsubj Mice,were
R4456 T6502 T6500 acl used,Mice
R4457 T6503 T6502 prep in,used
R4458 T6504 T6505 det this,study
R4459 T6505 T6503 pobj study,in
R4460 T6506 T6501 prep in,were
R4461 T6507 T6508 det a,background
R4462 T6508 T6506 pobj background,in
R4463 T6509 T6510 nmod 129Ola,C57BL6
R4464 T6510 T6508 nmod C57BL6,background
R4465 T6511 T6510 punct /,C57BL6
R4466 T6512 T6508 amod mixed,background
R4467 T6513 T6514 mark unless,noted
R4468 T6514 T6501 advcl noted,were
R4469 T6515 T6514 advmod differently,noted
R4470 T6516 T6501 punct .,were
R4471 T6518 T6519 det All,experiments
R4472 T6519 T6520 nsubjpass experiments,judged
R4473 T6521 T6519 acl involving,experiments
R4474 T6522 T6521 dobj mice,involving
R4475 T6523 T6520 auxpass were,judged
R4476 T6524 T6520 cc and,judged
R4477 T6525 T6520 conj approved,judged
R4478 T6526 T6525 agent by,approved
R4479 T6527 T6528 det the,committee
R4480 T6528 T6526 pobj committee,by
R4481 T6529 T6528 amod national,committee
R4482 T6530 T6528 prep for,committee
R4483 T6531 T6532 amod genetic,identification
R4484 T6532 T6530 pobj identification,for
R4485 T6533 T6532 prep of,identification
R4486 T6534 T6533 pobj organisms,of
R4487 T6535 T6528 cc and,committee
R4488 T6536 T6537 det the,committee
R4489 T6537 T6528 conj committee,committee
R4490 T6538 T6537 nmod animal,committee
R4491 T6539 T6537 amod ethical,committee
R4492 T6540 T6520 punct ", ",judged
R4493 T6541 T6520 cc and,judged
R4494 T6542 T6543 auxpass were,conducted
R4495 T6543 T6520 conj conducted,judged
R4496 T6544 T6543 prep according,conducted
R4497 T6545 T6544 prep to,according
R4498 T6546 T6547 amod national,guidelines
R4499 T6547 T6545 pobj guidelines,to
R4500 T6548 T6546 cc and,national
R4501 T6549 T6546 conj international,national
R4502 T6550 T6520 punct .,judged
R4503 T6587 T6588 compound UV,sensitivity
R4504 T6589 T6588 punct ", ",sensitivity
R4505 T6590 T6591 nmod UV,UDS
R4506 T6591 T6593 nmod UDS,activity
R4507 T6592 T6591 punct -,UDS
R4508 T6593 T6588 appos activity,sensitivity
R4509 T6594 T6591 punct ", ",UDS
R4510 T6595 T6596 compound UV,RRS
R4511 T6596 T6591 conj RRS,UDS
R4512 T6597 T6596 punct -,RRS
R4513 T6598 T6596 punct ", ",RRS
R4514 T6599 T6596 cc and,RRS
R4515 T6600 T6596 conj TFIIH,RRS
R4516 T6601 T6602 compound incision,excision
R4517 T6602 T6593 compound excision,activity
R4518 T6603 T6602 punct /,excision
R4519 T6604 T6588 punct .,sensitivity
R4520 T6606 T6607 nmod UV,survival
R4521 T6607 T6608 nmod survival,assays
R4522 T6608 T6618 nsubjpass assays,performed
R4523 T6609 T6607 punct ", ",survival
R4524 T6610 T6611 compound UV,UDS
R4525 T6611 T6607 conj UDS,survival
R4526 T6612 T6611 punct -,UDS
R4527 T6613 T6611 punct ", ",UDS
R4528 T6614 T6611 cc and,UDS
R4529 T6615 T6616 compound UV,RRS
R4530 T6616 T6611 conj RRS,UDS
R4531 T6617 T6616 punct -,RRS
R4532 T6619 T6618 auxpass were,performed
R4533 T6620 T6621 mark as,described
R4534 T6621 T6618 advcl described,performed
R4535 T6622 T6621 advmod previously,described
R4536 T6623 T6624 punct [,30
R4537 T6624 T6618 parataxis 30,performed
R4538 T6625 T6624 nummod 21,30
R4539 T6626 T6624 punct ",",30
R4540 T6627 T6624 punct ],30
R4541 T6628 T6618 punct .,performed
R4542 T6630 T6631 prep For,presented
R4543 T6632 T6633 compound UV,RRS
R4544 T6633 T6630 pobj RRS,For
R4545 T6634 T6633 punct -,RRS
R4546 T6635 T6631 punct ", ",presented
R4547 T6636 T6637 amod average,values
R4548 T6637 T6631 nsubjpass values,presented
R4549 T6638 T6637 prep from,values
R4550 T6639 T6640 det the,experiment
R4551 T6640 T6638 pobj experiment,from
R4552 T6641 T6640 amod representative,experiment
R4553 T6642 T6640 acl containing,experiment
R4554 T6643 T6644 nummod two,wt
R4555 T6644 T6645 nmod wt,line
R4556 T6645 T6642 dobj line,containing
R4557 T6646 T6644 punct ", ",wt
R4558 T6647 T6648 nummod three,TTD
R4559 T6648 T6644 conj TTD,wt
R4560 T6649 T6648 compound XpdTTD,TTD
R4561 T6650 T6648 punct /,TTD
R4562 T6651 T6648 punct ", ",TTD
R4563 T6652 T6653 nummod two,XPCS
R4564 T6653 T6648 conj XPCS,TTD
R4565 T6654 T6653 compound XpdTTD,XPCS
R4566 T6655 T6653 punct /,XPCS
R4567 T6656 T6653 punct ", ",XPCS
R4568 T6657 T6653 cc and,XPCS
R4569 T6658 T6659 nummod one,XP
R4570 T6659 T6653 conj XP,XPCS
R4571 T6660 T6659 compound XpdTTD,XP
R4572 T6661 T6659 punct /,XP
R4573 T6662 T6645 compound cell,line
R4574 T6663 T6631 auxpass are,presented
R4575 T6664 T6631 punct .,presented
R4576 T6666 T6667 det The,value
R4577 T6667 T6674 nsubj value,differs
R4578 T6668 T6669 punct ~,48
R4579 T6669 T6670 nummod 48,%
R4580 T6670 T6667 compound %,value
R4581 T6671 T6672 compound UV,UDS
R4582 T6672 T6667 compound UDS,value
R4583 T6673 T6672 punct -,UDS
R4584 T6675 T6667 acl presented,value
R4585 T6676 T6675 prep in,presented
R4586 T6677 T6678 det this,study
R4587 T6678 T6676 pobj study,in
R4588 T6679 T6667 prep for,value
R4589 T6680 T6681 compound XpdTTD,TTD
R4590 T6681 T6683 compound TTD,cells
R4591 T6682 T6681 punct /,TTD
R4592 T6683 T6679 pobj cells,for
R4593 T6684 T6674 prep from,differs
R4594 T6685 T6686 poss our,data
R4595 T6686 T6684 pobj data,from
R4596 T6687 T6688 advmod previously,published
R4597 T6688 T6686 amod published,data
R4598 T6689 T6686 prep of,data
R4599 T6690 T6691 nummod 25,%
R4600 T6691 T6692 compound %,UDS
R4601 T6692 T6689 pobj UDS,of
R4602 T6693 T6692 compound UV,UDS
R4603 T6694 T6692 punct -,UDS
R4604 T6695 T6696 punct [,21
R4605 T6696 T6674 parataxis 21,differs
R4606 T6697 T6696 punct ],21
R4607 T6698 T6674 punct ", ",differs
R4608 T6699 T6700 advmod possibly,because
R4609 T6700 T6674 prep because,differs
R4610 T6701 T6700 prep of,because
R4611 T6702 T6703 det the,variability
R4612 T6703 T6701 pobj variability,of
R4613 T6704 T6703 amod high,variability
R4614 T6705 T6703 amod intrinsic,variability
R4615 T6706 T6705 prep to,intrinsic
R4616 T6707 T6708 det the,assay
R4617 T6708 T6706 pobj assay,to
R4618 T6709 T6708 cc or,assay
R4619 T6710 T6711 amod routine,variations
R4620 T6711 T6708 conj variations,assay
R4621 T6712 T6708 prep in,assay
R4622 T6713 T6714 det the,conditions
R4623 T6714 T6712 pobj conditions,in
R4624 T6715 T6716 compound cell,culture
R4625 T6716 T6714 compound culture,conditions
R4626 T6717 T6674 punct .,differs
R4627 T6719 T6720 prep For,prepared
R4628 T6721 T6722 det the,assay
R4629 T6722 T6719 pobj assay,For
R4630 T6723 T6724 compound incision,excision
R4631 T6724 T6722 compound excision,assay
R4632 T6725 T6724 punct /,excision
R4633 T6726 T6722 compound activity,assay
R4634 T6727 T6720 punct ", ",prepared
R4635 T6728 T6729 amod recombinant,TFIIH
R4636 T6729 T6720 nsubjpass TFIIH,prepared
R4637 T6730 T6720 auxpass was,prepared
R4638 T6731 T6720 cc and,prepared
R4639 T6732 T6720 conj assayed,prepared
R4640 T6733 T6734 mark as,described
R4641 T6734 T6732 advcl described,assayed
R4642 T6735 T6734 advmod previously,described
R4643 T6736 T6737 punct [,27
R4644 T6737 T6732 parataxis 27,assayed
R4645 T6738 T6737 punct ],27
R4646 T6739 T6720 punct .,prepared
R4649 T6770 T6771 amod Comparative,immunofluorescence
R4650 T6772 T6771 punct .,immunofluorescence
R4651 T6774 T6775 compound Latex,labelling
R4652 T6775 T6777 nsubjpass labelling,performed
R4653 T6776 T6775 compound bead,labelling
R4654 T6778 T6775 cc and,labelling
R4655 T6779 T6780 amod comparative,analysis
R4656 T6780 T6775 conj analysis,labelling
R4657 T6781 T6780 compound immunofluorescence,analysis
R4658 T6782 T6780 prep of,analysis
R4659 T6783 T6784 det the,subunit
R4660 T6784 T6782 pobj subunit,of
R4661 T6785 T6784 compound p62,subunit
R4662 T6786 T6784 prep of,subunit
R4663 T6787 T6788 det the,TFIIH
R4664 T6788 T6786 pobj TFIIH,of
R4665 T6789 T6777 auxpass was,performed
R4666 T6790 T6791 mark as,described
R4667 T6791 T6777 advcl described,performed
R4668 T6792 T6791 advmod previously,described
R4669 T6793 T6794 punct [,17
R4670 T6794 T6791 parataxis 17,described
R4671 T6795 T6794 nummod 16,17
R4672 T6796 T6794 punct ",",17
R4673 T6797 T6794 punct ],17
R4674 T6798 T6777 advcl using,performed
R4675 T6799 T6800 amod primary,fibroblasts
R4676 T6800 T6798 dobj fibroblasts,using
R4677 T6801 T6800 nmod mouse,fibroblasts
R4678 T6802 T6800 amod embryonic,fibroblasts
R4679 T6803 T6798 prep at,using
R4680 T6804 T6805 nmod passages,2
R4681 T6805 T6803 pobj 2,at
R4682 T6806 T6807 punct –,5
R4683 T6807 T6805 prep 5,2
R4684 T6808 T6777 punct .,performed
R4685 T6810 T6811 nummod Two,lines
R4686 T6811 T6815 nsubjpass lines,used
R4687 T6812 T6810 cc or,Two
R4688 T6813 T6810 conj more,Two
R4689 T6814 T6811 compound cell,lines
R4690 T6816 T6811 prep per,lines
R4691 T6817 T6816 pobj genotype,per
R4692 T6818 T6819 punct (,except
R4693 T6819 T6811 parataxis except,lines
R4694 T6820 T6819 prep for,except
R4695 T6821 T6822 det the,cells
R4696 T6822 T6820 pobj cells,for
R4697 T6823 T6824 compound XpdTTD,†XP
R4698 T6824 T6822 compound †XP,cells
R4699 T6825 T6824 punct /,†XP
R4700 T6826 T6822 punct ", ",cells
R4701 T6827 T6828 prep in,used
R4702 T6828 T6822 relcl used,cells
R4703 T6829 T6827 pobj which,in
R4704 T6830 T6831 advmod only,line
R4705 T6831 T6828 nsubjpass line,used
R4706 T6832 T6831 nummod one,line
R4707 T6833 T6831 compound cell,line
R4708 T6834 T6828 auxpass was,used
R4709 T6835 T6828 prep in,used
R4710 T6836 T6837 amod repeated,experiments
R4711 T6837 T6835 pobj experiments,in
R4712 T6838 T6819 punct ),except
R4713 T6839 T6815 auxpass were,used
R4714 T6840 T6815 punct ", ",used
R4715 T6841 T6815 cc and,used
R4716 T6842 T6843 nsubjpass experiments,repeated
R4717 T6843 T6815 conj repeated,used
R4718 T6844 T6843 auxpass were,repeated
R4719 T6845 T6846 compound 2,6
R4720 T6846 T6848 nummod 6,times
R4721 T6847 T6846 punct –,6
R4722 T6848 T6843 dobj times,repeated
R4723 T6849 T6848 prep per,times
R4724 T6850 T6849 pobj genotype,per
R4725 T6851 T6843 punct .,repeated

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6321 360-365 NCBITaxon:10088 denotes mouse
T6322 366-375 UBERON:0000922 denotes embryonic
T6323 376-387 CL:0000057 denotes fibroblasts
T6324 437-449 CHEBI:51686 denotes Haematoxylin
T6325 573-578 UBERON:0000178 denotes Blood
T6326 606-612 NCBITaxon:33208 denotes Animal
T6327 613-618 UBERON:0000178 denotes Blood
T6328 712-719 CHEBI:46662 denotes mineral
T6329 765-769 NCBITaxon:10088 denotes Mice
T6330 882-886 NCBITaxon:10088 denotes mice
T6331 942-949 SO:0000704 denotes genetic
T6332 968-977 NCBITaxon:1 denotes organisms
T6333 986-992 NCBITaxon:33208 denotes animal
T6312 57-61 NCBITaxon:10088 denotes mice
T6313 77-80 PR:000007164 denotes Xpd
T6314 85-88 PR:000007164 denotes XPD
T6315 99-102 PR:000007164 denotes Xpd
T6316 109-113 NCBITaxon:10088 denotes mice
T6317 222-225 PR:000007164 denotes Xpd
T6318 235-238 PR:000007164 denotes Xpd
T6319 243-250 SO:0001023 denotes alleles
T6320 351-355 NCBITaxon:10088 denotes mice
T6564 1120-1125 GO:0005675 denotes TFIIH
T6565 1126-1134 MOP:0000780 denotes incision
T6566 1328-1331 PR:000007164 denotes Xpd
T6567 1344-1347 PR:000007164 denotes Xpd
T6568 1365-1368 PR:000007164 denotes Xpd
T6569 1450-1453 PR:000007164 denotes Xpd
T6570 1656-1664 MOP:0000780 denotes incision
T6571 1702-1707 GO:0005675 denotes TFIIH
T6750 1868-1882 _FRAGMENT denotes p62 subunit of
T6751 1887-1892 PR:000008317 denotes TFIIH
T6752 1887-1892 GO:0005675 denotes TFIIH
T6753 1953-1958 NCBITaxon:10088 denotes mouse
T6754 1959-1968 UBERON:0000922 denotes embryonic
T6755 1969-1980 CL:0000057 denotes fibroblasts
T6756 2050-2053 PR:000007164 denotes Xpd
R4647 T6751 T6750 _lexicallyChainedTo TFIIH,p62 subunit of

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6342 235-238 PR_EXT:000007164 denotes Xpd
T6343 243-250 SO_EXT:0001023 denotes alleles
T6344 260-269 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T6345 270-278 SO_EXT:sequence_coding_function denotes encoding
T6346 299-310 SO_EXT:sequence_alteration_entity_or_process denotes alterations
T6347 351-355 NCBITaxon:10088 denotes mice
T6348 360-365 NCBITaxon:10088 denotes mouse
T6349 366-375 UBERON:0000922 denotes embryonic
T6350 376-387 CL:0000057 denotes fibroblasts
T6351 437-449 CHEBI:51686 denotes Haematoxylin
T6352 454-459 CHEBI_EXT:eosin denotes eosin
T6353 517-527 CHEBI_SO_EXT:amino_acid denotes Amino acid
T6354 573-578 UBERON:0000178 denotes Blood
T6355 606-612 NCBITaxon:33208 denotes Animal
T6356 613-618 UBERON:0000178 denotes Blood
T6357 707-711 UBERON_EXT:bone_element_or_tissue denotes bone
T6358 712-719 CHEBI:46662 denotes mineral
T6359 765-769 NCBITaxon:10088 denotes Mice
T6360 882-886 NCBITaxon:10088 denotes mice
T6361 942-949 SO_EXT:0000704 denotes genetic
T6362 968-977 NCBITaxon:1 denotes organisms
T6363 986-992 NCBITaxon:33208 denotes animal
T6758 1868-1882 _FRAGMENT denotes p62 subunit of
T6759 1887-1892 PR_EXT:000008317 denotes TFIIH
T6760 1887-1892 GO:0005675 denotes TFIIH
T6761 1953-1958 NCBITaxon:10088 denotes mouse
T6762 1959-1968 UBERON:0000922 denotes embryonic
T6763 1969-1980 CL:0000057 denotes fibroblasts
T6764 2010-2014 CL_GO_EXT:cell denotes cell
T6765 2025-2033 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T6766 2050-2053 PR_EXT:000007164 denotes Xpd
T6767 2061-2066 CL_GO_EXT:cell denotes cells
T6768 2086-2090 CL_GO_EXT:cell denotes cell
T6769 2185-2193 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T6334 50-56 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T6335 57-61 NCBITaxon:10088 denotes mice
T6336 77-80 PR_EXT:000007164 denotes Xpd
T6337 85-88 PR_EXT:000007164 denotes XPD
T6338 99-102 PR_EXT:000007164 denotes Xpd
T6339 109-113 NCBITaxon:10088 denotes mice
T6340 207-217 SO_EXT:engineered_biological_sequence denotes constructs
T6341 222-225 PR_EXT:000007164 denotes Xpd
T6572 1120-1125 GO:0005675 denotes TFIIH
T6573 1126-1134 MOP:0000780 denotes incision
T6574 1135-1143 SO_EXT:sequence_deletion_process denotes excision
T6575 1318-1320 SO_EXT:wild_type_entity_or_quality denotes wt
T6576 1328-1331 PR_EXT:000007164 denotes Xpd
T6577 1344-1347 PR_EXT:000007164 denotes Xpd
T6578 1365-1368 PR_EXT:000007164 denotes Xpd
T6579 1375-1379 CL_GO_EXT:cell denotes cell
T6580 1450-1453 PR_EXT:000007164 denotes Xpd
T6581 1461-1466 CL_GO_EXT:cell denotes cells
T6582 1623-1627 CL_GO_EXT:cell denotes cell
T6583 1656-1664 MOP:0000780 denotes incision
T6584 1665-1673 SO_EXT:sequence_deletion_process denotes excision
T6585 1690-1701 GO_SO_EXT:sequence_rearrangement_process denotes recombinant
T6586 1702-1707 GO:0005675 denotes TFIIH
T6757 1807-1816 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labelling
R4648 T6759 T6758 _lexicallyChainedTo TFIIH,p62 subunit of

2_test

Id Subject Object Predicate Lexical cue
17020410-9651581-84795165 145-147 9651581 denotes 21
17020410-9426063-84795166 148-150 9426063 denotes 22
17020410-9651581-84795167 568-570 9651581 denotes 21
17020410-11950998-84795168 760-762 11950998 denotes 15
17020410-9651581-84795169 1233-1235 9651581 denotes 21
17020410-12531012-84795170 1236-1238 12531012 denotes 30
17020410-9651581-84795171 1525-1527 9651581 denotes 21
17020410-12820975-84795172 1758-1760 12820975 denotes 27
17020410-11242112-84795173 1932-1934 11242112 denotes 16
17020410-12393803-84795174 1935-1937 12393803 denotes 17
T86762 145-147 9651581 denotes 21
T68945 148-150 9426063 denotes 22
T30574 568-570 9651581 denotes 21
T65613 760-762 11950998 denotes 15
T19802 1233-1235 9651581 denotes 21
T38157 1236-1238 12531012 denotes 30
T62073 1525-1527 9651581 denotes 21
T15235 1758-1760 12820975 denotes 27
T99220 1932-1934 11242112 denotes 16
T28976 1935-1937 12393803 denotes 17