PMC:1584416 / 29607-30120
Annnotations
craft-sa-dev
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proteins originating from presumed null alleles were biochemically characterised as inactive in basal transcription [27], providing an explanation as to why these alleles failed to rescue lethality in haploid S. pombe with a null mutation in the XPD homologue rad15 [19]. Our data suggest that certain presumed null alleles, although unable on their own to support basal transcription, may in fact have a substantial impact on disease outcome in compound heterozygous humans, as they do in mouse models."}
craft-ca-core-dev
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craft-ca-core-ex-dev
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2_test
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