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Similar to the Xpd †XPCS allele, the homozygous lethal Xpd †XP allele rescued cutaneous symptoms including hair loss (except locally during the first round; unpublished data), reduced cysteine content (cysteine index 9.3 ± 0.9 standard deviation [87% of wt], p = 0.01 versus TTD), ageing-associated premature cachexia (males and females were 36.1 ± 6.4 g [93% of wt] and 39.2 ± 3.2 g [116% of wt], respectively), and reduced life span (Table 2)."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T2511","span":{"begin":64,"end":70},"obj":"SO:0001023"},{"id":"T2512","span":{"begin":108,"end":112},"obj":"UBERON:0001037"},{"id":"T2513","span":{"begin":282,"end":288},"obj":"GO:0007568"},{"id":"T2514","span":{"begin":426,"end":435},"obj":"UBERON:0000104"},{"id":"T2508","span":{"begin":16,"end":19},"obj":"PR:000007164"},{"id":"T2509","span":{"begin":26,"end":32},"obj":"SO:0001023"},{"id":"T2510","span":{"begin":56,"end":59},"obj":"PR:000007164"}],"text":" Similar to the Xpd †XPCS allele, the homozygous lethal Xpd †XP allele rescued cutaneous symptoms including hair loss (except locally during the first round; unpublished data), reduced cysteine content (cysteine index 9.3 ± 0.9 standard deviation [87% of wt], p = 0.01 versus TTD), ageing-associated premature cachexia (males and females were 36.1 ± 6.4 g [93% of wt] and 39.2 ± 3.2 g [116% of wt], respectively), and reduced life span (Table 2)."}

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