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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1570349","sourcedb":"PMC","sourceid":"1570349","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1570349","text":"Mathematically, the inverse problem is formulated as an nonlinear optimization problem with equality constraint on the x-abscissa of the G1/S point, SN1. The bifurcation diagram corresponding to the solution (k25 = 1.182, φE2F1 = 0.0992, φAP-1 = 0.0109) is given in Figure 13. Row 2 of Table 3 summarizes the number of iterations required.","tracks":[]}