
PMC:1564426 / 50963-51509
Annnotations
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T26510 | 16-33 | SO_EXT:0001644 | denotes | targeting vectors |
T26511 | 49-52 | PR_EXT:000004122 | denotes | Apc |
T26512 | 72-75 | SO_EXT:0000153 | denotes | BAC |
T26513 | 76-81 | SO_EXT:sequence_cloned_entity | denotes | clone |
T26514 | 116-124 | SO_EXT:biological_sequence | denotes | sequence |
T26515 | 128-131 | PR_EXT:000004122 | denotes | Apc |
T26516 | 147-153 | SO_EXT:0000204 | denotes | 5′ UTR |
T26517 | 158-162 | SO_EXT:0000147 | denotes | exon |
T26518 | 229-238 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
T26519 | 262-265 | SO_EXT:0000153 | denotes | BAC |
T26520 | 278-291 | SO_EXT:sequence_alteration_entity_or_process | denotes | modifications |
T26521 | 312-319 | SO_EXT:0001026 | denotes | genomic |
T26522 | 320-328 | SO_EXT:biological_sequence | denotes | sequence |
T26523 | 342-345 | PR_EXT:000004122 | denotes | Apc |
T26524 | 346-351 | SO_EXT:0000147 | denotes | exons |
T26525 | 393-399 | SO_EXT:0000440 | denotes | vector |
T26526 | 412-421 | SO_EXT:0000346 | denotes | loxP site |
T26527 | 442-448 | SO_EXT:0000188 | denotes | intron |
T26528 | 464-468 | SO_EXT:0000346 | denotes | loxP |
T26529 | 469-472 | SO_EXT:0000350 | denotes | FRT |
T26530 | 473-476 | GO_EXT:phosphoglycerate_kinase | denotes | PGK |
T26531 | 476-479 | CHEBI_GO_EXT:neomycin_or_neomycin_phosphotransferase | denotes | neo |
T26532 | 476-480 | GO_EXT:0008910 | denotes | neor |
T26533 | 481-484 | SO_EXT:0000350 | denotes | FRT |
T26534 | 495-503 | SO_EXT:0005853 | denotes | cassette |
T26535 | 525-528 | PR_EXT:000004122 | denotes | Apc |
T26536 | 529-533 | SO_EXT:0000704 | denotes | gene |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T26491 | 16-33 | SO:0001644 | denotes | targeting vectors |
T26492 | 49-52 | PR:000004122 | denotes | Apc |
T26493 | 72-75 | SO:0000153 | denotes | BAC |
T26494 | 128-131 | PR:000004122 | denotes | Apc |
T26495 | 147-153 | SO:0000204 | denotes | 5′ UTR |
T26496 | 158-162 | SO:0000147 | denotes | exon |
T26497 | 262-265 | SO:0000153 | denotes | BAC |
T26498 | 312-319 | SO:0001026 | denotes | genomic |
T26499 | 342-345 | PR:000004122 | denotes | Apc |
T26500 | 346-351 | SO:0000147 | denotes | exons |
T26501 | 393-399 | SO:0000440 | denotes | vector |
T26502 | 412-421 | SO:0000346 | denotes | loxP site |
T26503 | 442-448 | SO:0000188 | denotes | intron |
T26504 | 464-468 | SO:0000346 | denotes | loxP |
T26505 | 469-472 | SO:0000350 | denotes | FRT |
T26506 | 481-484 | SO:0000350 | denotes | FRT |
T26507 | 495-503 | SO:0005853 | denotes | cassette |
T26508 | 525-528 | PR:000004122 | denotes | Apc |
T26509 | 529-533 | SO:0000704 | denotes | gene |
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T26537 | 0-12 | NN | denotes | Construction |
T26538 | 13-15 | IN | denotes | of |
T26539 | 16-25 | NN | denotes | targeting |
T26540 | 26-33 | NNS | denotes | vectors |
T26541 | 33-34 | . | denotes | . |
T26542 | 34-165 | sentence | denotes | To target the Apc locus, we obtained BAC clone RP23-233F17 that contains all the sequence of Apc except for the 5′ UTR and exon 1. |
T26543 | 35-37 | TO | denotes | To |
T26544 | 38-44 | VB | denotes | target |
T26545 | 63-71 | VBD | denotes | obtained |
T26546 | 45-48 | DT | denotes | the |
T26547 | 53-58 | NN | denotes | locus |
T26548 | 49-52 | NN | denotes | Apc |
T26549 | 58-60 | , | denotes | , |
T26550 | 60-62 | PRP | denotes | we |
T26551 | 72-75 | NN | denotes | BAC |
T26552 | 76-81 | NN | denotes | clone |
T26553 | 82-86 | NN | denotes | RP23 |
T26554 | 87-93 | NN | denotes | 233F17 |
T26555 | 86-87 | HYPH | denotes | - |
T26556 | 94-98 | WDT | denotes | that |
T26557 | 99-107 | VBZ | denotes | contains |
T26558 | 108-111 | PDT | denotes | all |
T26559 | 116-124 | NN | denotes | sequence |
T26560 | 112-115 | DT | denotes | the |
T26561 | 125-127 | IN | denotes | of |
T26562 | 128-131 | NN | denotes | Apc |
T26563 | 132-138 | IN | denotes | except |
T26564 | 139-142 | IN | denotes | for |
T26565 | 143-146 | DT | denotes | the |
T26566 | 150-153 | NN | denotes | UTR |
T26567 | 147-148 | CD | denotes | 5 |
T26568 | 148-149 | SYM | denotes | ′ |
T26569 | 154-157 | CC | denotes | and |
T26570 | 158-162 | NN | denotes | exon |
T26571 | 163-164 | CD | denotes | 1 |
T26572 | 164-165 | . | denotes | . |
T26573 | 165-307 | sentence | denotes | Using a recombineering-based method for generating conditional mutations [12,13], subcloning of BAC and further modifications were conducted. |
T26574 | 166-171 | VBG | denotes | Using |
T26575 | 297-306 | VBN | denotes | conducted |
T26576 | 172-173 | DT | denotes | a |
T26577 | 195-201 | NN | denotes | method |
T26578 | 174-188 | NN | denotes | recombineering |
T26579 | 189-194 | JJ | denotes | based |
T26580 | 188-189 | HYPH | denotes | - |
T26581 | 202-205 | IN | denotes | for |
T26582 | 206-216 | VBG | denotes | generating |
T26583 | 217-228 | JJ | denotes | conditional |
T26584 | 229-238 | NNS | denotes | mutations |
T26585 | 239-240 | -LRB- | denotes | [ |
T26586 | 243-245 | CD | denotes | 13 |
T26587 | 240-242 | CD | denotes | 12 |
T26588 | 242-243 | , | denotes | , |
T26589 | 245-246 | -RRB- | denotes | ] |
T26590 | 246-248 | , | denotes | , |
T26591 | 248-258 | NN | denotes | subcloning |
T26592 | 259-261 | IN | denotes | of |
T26593 | 262-265 | NN | denotes | BAC |
T26594 | 266-269 | CC | denotes | and |
T26595 | 270-277 | JJ | denotes | further |
T26596 | 278-291 | NNS | denotes | modifications |
T26597 | 292-296 | VBD | denotes | were |
T26598 | 306-307 | . | denotes | . |
T26599 | 307-546 | sentence | denotes | The genomic sequence encompassing Apc exons 11 to 15 was first subcloned into pBR322 vector, and then a loxP site was introduced into intron 13 followed by loxP-FRT-PGKneor-FRT selection cassette into intron14 of the Apc gene (Figure 1A). |
T26600 | 308-311 | DT | denotes | The |
T26601 | 320-328 | NN | denotes | sequence |
T26602 | 312-319 | JJ | denotes | genomic |
T26603 | 371-380 | VBN | denotes | subcloned |
T26604 | 329-341 | VBG | denotes | encompassing |
T26605 | 342-345 | NN | denotes | Apc |
T26606 | 352-354 | CD | denotes | 11 |
T26607 | 346-351 | NNS | denotes | exons |
T26608 | 355-357 | IN | denotes | to |
T26609 | 358-360 | CD | denotes | 15 |
T26610 | 361-364 | VBD | denotes | was |
T26611 | 365-370 | RB | denotes | first |
T26612 | 381-385 | IN | denotes | into |
T26613 | 386-392 | NN | denotes | pBR322 |
T26614 | 393-399 | NN | denotes | vector |
T26615 | 399-401 | , | denotes | , |
T26616 | 401-404 | CC | denotes | and |
T26617 | 405-409 | RB | denotes | then |
T26618 | 452-460 | VBN | denotes | followed |
T26619 | 410-411 | DT | denotes | a |
T26620 | 417-421 | NN | denotes | site |
T26621 | 412-416 | NN | denotes | loxP |
T26622 | 422-425 | VBD | denotes | was |
T26623 | 426-436 | VBN | denotes | introduced |
T26624 | 437-441 | IN | denotes | into |
T26625 | 442-448 | NN | denotes | intron |
T26626 | 449-451 | CD | denotes | 13 |
T26627 | 461-463 | IN | denotes | by |
T26628 | 464-468 | NN | denotes | loxP |
T26629 | 469-472 | NN | denotes | FRT |
T26630 | 468-469 | HYPH | denotes | - |
T26631 | 495-503 | NN | denotes | cassette |
T26632 | 472-473 | HYPH | denotes | - |
T26633 | 473-480 | NN | denotes | PGKneor |
T26634 | 481-484 | NN | denotes | FRT |
T26635 | 480-481 | HYPH | denotes | - |
T26636 | 485-494 | NN | denotes | selection |
T26637 | 504-508 | IN | denotes | into |
T26638 | 509-517 | NN | denotes | intron14 |
T26639 | 518-520 | IN | denotes | of |
T26640 | 521-524 | DT | denotes | the |
T26641 | 529-533 | NN | denotes | gene |
T26642 | 525-528 | NN | denotes | Apc |
T26643 | 534-535 | -LRB- | denotes | ( |
T26644 | 542-544 | NN | denotes | 1A |
T26645 | 535-541 | NN | denotes | Figure |
T26646 | 544-545 | -RRB- | denotes | ) |
T26647 | 545-546 | . | denotes | . |
R8050 | T26538 | T26537 | prep | of,Construction |
R8051 | T26539 | T26540 | compound | targeting,vectors |
R8052 | T26540 | T26538 | pobj | vectors,of |
R8053 | T26541 | T26537 | punct | .,Construction |
R8054 | T26543 | T26544 | aux | To,target |
R8055 | T26544 | T26545 | advcl | target,obtained |
R8056 | T26546 | T26547 | det | the,locus |
R8057 | T26547 | T26544 | dobj | locus,target |
R8058 | T26548 | T26547 | compound | Apc,locus |
R8059 | T26549 | T26545 | punct | ", ",obtained |
R8060 | T26550 | T26545 | nsubj | we,obtained |
R8061 | T26551 | T26552 | compound | BAC,clone |
R8062 | T26552 | T26545 | dobj | clone,obtained |
R8063 | T26553 | T26554 | compound | RP23,233F17 |
R8064 | T26554 | T26552 | appos | 233F17,clone |
R8065 | T26555 | T26554 | punct | -,233F17 |
R8066 | T26556 | T26557 | dep | that,contains |
R8067 | T26557 | T26552 | relcl | contains,clone |
R8068 | T26558 | T26559 | predet | all,sequence |
R8069 | T26559 | T26557 | dobj | sequence,contains |
R8070 | T26560 | T26559 | det | the,sequence |
R8071 | T26561 | T26559 | prep | of,sequence |
R8072 | T26562 | T26561 | pobj | Apc,of |
R8073 | T26563 | T26559 | prep | except,sequence |
R8074 | T26564 | T26563 | prep | for,except |
R8075 | T26565 | T26566 | det | the,UTR |
R8076 | T26566 | T26564 | pobj | UTR,for |
R8077 | T26567 | T26566 | nummod | 5,UTR |
R8078 | T26568 | T26567 | punct | ′,5 |
R8079 | T26569 | T26566 | cc | and,UTR |
R8080 | T26570 | T26566 | conj | exon,UTR |
R8081 | T26571 | T26570 | nummod | 1,exon |
R8082 | T26572 | T26545 | punct | .,obtained |
R8083 | T26574 | T26575 | advcl | Using,conducted |
R8084 | T26576 | T26577 | det | a,method |
R8085 | T26577 | T26574 | dobj | method,Using |
R8086 | T26578 | T26579 | npadvmod | recombineering,based |
R8087 | T26579 | T26577 | amod | based,method |
R8088 | T26580 | T26579 | punct | -,based |
R8089 | T26581 | T26577 | prep | for,method |
R8090 | T26582 | T26581 | pcomp | generating,for |
R8091 | T26583 | T26584 | amod | conditional,mutations |
R8092 | T26584 | T26582 | dobj | mutations,generating |
R8093 | T26585 | T26586 | punct | [,13 |
R8094 | T26586 | T26574 | parataxis | 13,Using |
R8095 | T26587 | T26586 | nummod | 12,13 |
R8096 | T26588 | T26586 | punct | ",",13 |
R8097 | T26589 | T26586 | punct | ],13 |
R8098 | T26590 | T26575 | punct | ", ",conducted |
R8099 | T26591 | T26575 | nsubjpass | subcloning,conducted |
R8100 | T26592 | T26591 | prep | of,subcloning |
R8101 | T26593 | T26592 | pobj | BAC,of |
R8102 | T26594 | T26591 | cc | and,subcloning |
R8103 | T26595 | T26596 | amod | further,modifications |
R8104 | T26596 | T26591 | conj | modifications,subcloning |
R8105 | T26597 | T26575 | auxpass | were,conducted |
R8106 | T26598 | T26575 | punct | .,conducted |
R8107 | T26600 | T26601 | det | The,sequence |
R8108 | T26601 | T26603 | nsubjpass | sequence,subcloned |
R8109 | T26602 | T26601 | amod | genomic,sequence |
R8110 | T26604 | T26601 | acl | encompassing,sequence |
R8111 | T26605 | T26606 | nmod | Apc,11 |
R8112 | T26606 | T26604 | dobj | 11,encompassing |
R8113 | T26607 | T26606 | nmod | exons,11 |
R8114 | T26608 | T26606 | prep | to,11 |
R8115 | T26609 | T26608 | pobj | 15,to |
R8116 | T26610 | T26603 | auxpass | was,subcloned |
R8117 | T26611 | T26603 | advmod | first,subcloned |
R8118 | T26612 | T26603 | prep | into,subcloned |
R8119 | T26613 | T26614 | compound | pBR322,vector |
R8120 | T26614 | T26612 | pobj | vector,into |
R8121 | T26615 | T26603 | punct | ", ",subcloned |
R8122 | T26616 | T26603 | cc | and,subcloned |
R8123 | T26617 | T26618 | advmod | then,followed |
R8124 | T26618 | T26603 | conj | followed,subcloned |
R8125 | T26619 | T26620 | det | a,site |
R8126 | T26620 | T26618 | nsubjpass | site,followed |
R8127 | T26621 | T26620 | compound | loxP,site |
R8128 | T26622 | T26618 | auxpass | was,followed |
R8129 | T26623 | T26618 | aux | introduced,followed |
R8130 | T26624 | T26618 | prep | into,followed |
R8131 | T26625 | T26624 | pobj | intron,into |
R8132 | T26626 | T26625 | nummod | 13,intron |
R8133 | T26627 | T26618 | agent | by,followed |
R8134 | T26628 | T26629 | nmod | loxP,FRT |
R8135 | T26629 | T26631 | nmod | FRT,cassette |
R8136 | T26630 | T26629 | punct | -,FRT |
R8137 | T26631 | T26627 | pobj | cassette,by |
R8138 | T26632 | T26629 | punct | -,FRT |
R8139 | T26633 | T26634 | compound | PGKneor,FRT |
R8140 | T26634 | T26629 | appos | FRT,FRT |
R8141 | T26635 | T26634 | punct | -,FRT |
R8142 | T26636 | T26631 | compound | selection,cassette |
R8143 | T26637 | T26631 | prep | into,cassette |
R8144 | T26638 | T26637 | pobj | intron14,into |
R8145 | T26639 | T26638 | prep | of,intron14 |
R8146 | T26640 | T26641 | det | the,gene |
R8147 | T26641 | T26639 | pobj | gene,of |
R8148 | T26642 | T26641 | compound | Apc,gene |
R8149 | T26643 | T26644 | punct | (,1A |
R8150 | T26644 | T26618 | parataxis | 1A,followed |
R8151 | T26645 | T26644 | compound | Figure,1A |
R8152 | T26646 | T26644 | punct | ),1A |
R8153 | T26647 | T26618 | punct | .,followed |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
17002498-11352566-85593533 | 240-242 | 11352566 | denotes | 12 |
17002498-12618378-85593534 | 243-245 | 12618378 | denotes | 13 |
T46410 | 240-242 | 11352566 | denotes | 12 |
T7670 | 243-245 | 12618378 | denotes | 13 |