PMC:1564426 / 0-326 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1564426","sourcedb":"PMC","sourceid":"1564426","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1564426","text":"Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus\nRole of APC in Skin and Its Appendages\n\nAbstract\nThe tumor suppressor gene Apc (adenomatous polyposis coli) is a member of the Wnt signaling pathway that is involved in development and tumorigenesis. Heterozygous knockout mice for Apc have","divisions":[{"label":"article-title","span":{"begin":0,"end":86}},{"label":"alt-title","span":{"begin":87,"end":125}}],"tracks":[{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T496","span":{"begin":0,"end":26},"obj":"PR_EXT:000004122"},{"id":"T497","span":{"begin":28,"end":31},"obj":"PR_EXT:000004122"},{"id":"T498","span":{"begin":56,"end":75},"obj":"GO:0043588"},{"id":"T499","span":{"begin":56,"end":70},"obj":"_FRAGMENT"},{"id":"T500","span":{"begin":80,"end":86},"obj":"GO:0048538"},{"id":"T501","span":{"begin":71,"end":75},"obj":"UBERON_EXT:zone_of_skin_or_skin_of_body"},{"id":"T502","span":{"begin":80,"end":86},"obj":"UBERON:0002370"},{"id":"T503","span":{"begin":157,"end":161},"obj":"SO_EXT:0000704"},{"id":"T504","span":{"begin":162,"end":165},"obj":"PR_EXT:000004122"},{"id":"T505","span":{"begin":167,"end":193},"obj":"PR_EXT:000004122"},{"id":"T506","span":{"begin":214,"end":235},"obj":"GO:0016055"},{"id":"T507","span":{"begin":309,"end":313},"obj":"NCBITaxon:10088"},{"id":"T508","span":{"begin":318,"end":321},"obj":"PR_EXT:000004122"}],"relations":[{"id":"R4","pred":"_lexicallyChainedTo","subj":"T500","obj":"T499"}],"attributes":[{"subj":"T496","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T497","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T498","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T499","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T500","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T501","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T502","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T503","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T504","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T505","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T506","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T507","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T508","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T435","span":{"begin":0,"end":26},"obj":"PR:000004122"},{"id":"T436","span":{"begin":28,"end":31},"obj":"PR:000004122"},{"id":"T437","span":{"begin":56,"end":75},"obj":"GO:0043588"},{"id":"T438","span":{"begin":56,"end":70},"obj":"_FRAGMENT"},{"id":"T439","span":{"begin":80,"end":86},"obj":"GO:0048538"},{"id":"T440","span":{"begin":80,"end":86},"obj":"UBERON:0002370"},{"id":"T441","span":{"begin":157,"end":161},"obj":"SO:0000704"},{"id":"T442","span":{"begin":162,"end":165},"obj":"PR:000004122"},{"id":"T443","span":{"begin":167,"end":193},"obj":"PR:000004122"},{"id":"T444","span":{"begin":214,"end":235},"obj":"GO:0016055"},{"id":"T445","span":{"begin":309,"end":313},"obj":"NCBITaxon:10088"},{"id":"T446","span":{"begin":318,"end":321},"obj":"PR:000004122"}],"relations":[{"id":"R1","pred":"_lexicallyChainedTo","subj":"T439","obj":"T438"}],"attributes":[{"subj":"T435","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T436","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T437","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T438","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T439","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T440","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T441","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T442","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T443","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T444","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T445","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T446","pred":"source","obj":"craft-ca-core-dev"}]},{"project":"craft-sa-dev","denotations":[{"id":"T566","span":{"begin":0,"end":11},"obj":"JJ"},{"id":"T567","span":{"begin":22,"end":26},"obj":"NN"},{"id":"T568","span":{"begin":0,"end":86},"obj":"sentence"},{"id":"T569","span":{"begin":12,"end":21},"obj":"NN"},{"id":"T570","span":{"begin":36,"end":44},"obj":"VBN"},{"id":"T571","span":{"begin":27,"end":28},"obj":"-LRB-"},{"id":"T572","span":{"begin":28,"end":31},"obj":"NN"},{"id":"T573","span":{"begin":31,"end":32},"obj":"-RRB-"},{"id":"T574","span":{"begin":33,"end":35},"obj":"VBZ"},{"id":"T575","span":{"begin":45,"end":48},"obj":"IN"},{"id":"T576","span":{"begin":49,"end":55},"obj":"JJ"},{"id":"T577","span":{"begin":56,"end":67},"obj":"NN"},{"id":"T578","span":{"begin":68,"end":70},"obj":"IN"},{"id":"T579","span":{"begin":71,"end":75},"obj":"NN"},{"id":"T580","span":{"begin":76,"end":79},"obj":"CC"},{"id":"T581","span":{"begin":80,"end":86},"obj":"NN"},{"id":"T584","span":{"begin":86,"end":286},"obj":"sentence"},{"id":"T585","span":{"begin":136,"end":139},"obj":"DT"},{"id":"T586","span":{"begin":157,"end":161},"obj":"NN"},{"id":"T587","span":{"begin":140,"end":145},"obj":"NN"},{"id":"T588","span":{"begin":146,"end":156},"obj":"NN"},{"id":"T589","span":{"begin":195,"end":197},"obj":"VBZ"},{"id":"T590","span":{"begin":162,"end":165},"obj":"NN"},{"id":"T591","span":{"begin":166,"end":167},"obj":"-LRB-"},{"id":"T592","span":{"begin":167,"end":178},"obj":"FW"},{"id":"T593","span":{"begin":189,"end":193},"obj":"FW"},{"id":"T594","span":{"begin":179,"end":188},"obj":"FW"},{"id":"T595","span":{"begin":193,"end":194},"obj":"-RRB-"},{"id":"T596","span":{"begin":198,"end":199},"obj":"DT"},{"id":"T597","span":{"begin":200,"end":206},"obj":"NN"},{"id":"T598","span":{"begin":207,"end":209},"obj":"IN"},{"id":"T599","span":{"begin":210,"end":213},"obj":"DT"},{"id":"T600","span":{"begin":228,"end":235},"obj":"NN"},{"id":"T601","span":{"begin":214,"end":217},"obj":"NN"},{"id":"T602","span":{"begin":218,"end":227},"obj":"NN"},{"id":"T603","span":{"begin":236,"end":240},"obj":"WDT"},{"id":"T604","span":{"begin":244,"end":252},"obj":"VBN"},{"id":"T605","span":{"begin":241,"end":243},"obj":"VBZ"},{"id":"T606","span":{"begin":253,"end":255},"obj":"IN"},{"id":"T607","span":{"begin":256,"end":267},"obj":"NN"},{"id":"T608","span":{"begin":268,"end":271},"obj":"CC"},{"id":"T609","span":{"begin":272,"end":285},"obj":"NN"},{"id":"T610","span":{"begin":285,"end":286},"obj":"."},{"id":"T612","span":{"begin":287,"end":299},"obj":"JJ"},{"id":"T613","span":{"begin":300,"end":308},"obj":"NN"},{"id":"T614","span":{"begin":309,"end":313},"obj":"NNS"},{"id":"T615","span":{"begin":322,"end":326},"obj":"VBP"},{"id":"T616","span":{"begin":314,"end":317},"obj":"IN"},{"id":"T617","span":{"begin":318,"end":321},"obj":"NN"}],"relations":[{"id":"R7","pred":"amod","subj":"T566","obj":"T567"},{"id":"R8","pred":"nsubjpass","subj":"T567","obj":"T570"},{"id":"R9","pred":"compound","subj":"T569","obj":"T567"},{"id":"R10","pred":"punct","subj":"T571","obj":"T567"},{"id":"R11","pred":"appos","subj":"T572","obj":"T567"},{"id":"R12","pred":"punct","subj":"T573","obj":"T570"},{"id":"R13","pred":"auxpass","subj":"T574","obj":"T570"},{"id":"R14","pred":"prep","subj":"T575","obj":"T570"},{"id":"R15","pred":"amod","subj":"T576","obj":"T577"},{"id":"R16","pred":"pobj","subj":"T577","obj":"T575"},{"id":"R17","pred":"prep","subj":"T578","obj":"T577"},{"id":"R18","pred":"pobj","subj":"T579","obj":"T578"},{"id":"R19","pred":"cc","subj":"T580","obj":"T579"},{"id":"R20","pred":"conj","subj":"T581","obj":"T579"},{"id":"R21","pred":"det","subj":"T585","obj":"T586"},{"id":"R22","pred":"nsubj","subj":"T586","obj":"T589"},{"id":"R23","pred":"compound","subj":"T587","obj":"T588"},{"id":"R24","pred":"compound","subj":"T588","obj":"T586"},{"id":"R25","pred":"appos","subj":"T590","obj":"T586"},{"id":"R26","pred":"punct","subj":"T591","obj":"T590"},{"id":"R27","pred":"nmod","subj":"T592","obj":"T593"},{"id":"R28","pred":"appos","subj":"T593","obj":"T590"},{"id":"R29","pred":"nmod","subj":"T594","obj":"T593"},{"id":"R30","pred":"punct","subj":"T595","obj":"T589"},{"id":"R31","pred":"det","subj":"T596","obj":"T597"},{"id":"R32","pred":"attr","subj":"T597","obj":"T589"},{"id":"R33","pred":"prep","subj":"T598","obj":"T597"},{"id":"R34","pred":"det","subj":"T599","obj":"T600"},{"id":"R35","pred":"pobj","subj":"T600","obj":"T598"},{"id":"R36","pred":"compound","subj":"T601","obj":"T600"},{"id":"R37","pred":"compound","subj":"T602","obj":"T600"},{"id":"R38","pred":"dep","subj":"T603","obj":"T604"},{"id":"R39","pred":"relcl","subj":"T604","obj":"T600"},{"id":"R40","pred":"auxpass","subj":"T605","obj":"T604"},{"id":"R41","pred":"prep","subj":"T606","obj":"T604"},{"id":"R42","pred":"pobj","subj":"T607","obj":"T606"},{"id":"R43","pred":"cc","subj":"T608","obj":"T607"},{"id":"R44","pred":"conj","subj":"T609","obj":"T607"},{"id":"R45","pred":"punct","subj":"T610","obj":"T589"},{"id":"R46","pred":"amod","subj":"T612","obj":"T613"},{"id":"R47","pred":"compound","subj":"T613","obj":"T614"},{"id":"R48","pred":"nsubj","subj":"T614","obj":"T615"},{"id":"R49","pred":"prep","subj":"T616","obj":"T614"},{"id":"R50","pred":"pobj","subj":"T617","obj":"T616"}],"attributes":[{"subj":"T566","pred":"source","obj":"craft-sa-dev"},{"subj":"T567","pred":"source","obj":"craft-sa-dev"},{"subj":"T568","pred":"source","obj":"craft-sa-dev"},{"subj":"T569","pred":"source","obj":"craft-sa-dev"},{"subj":"T570","pred":"source","obj":"craft-sa-dev"},{"subj":"T571","pred":"source","obj":"craft-sa-dev"},{"subj":"T572","pred":"source","obj":"craft-sa-dev"},{"subj":"T573","pred":"source","obj":"craft-sa-dev"},{"subj":"T574","pred":"source","obj":"craft-sa-dev"},{"subj":"T575","pred":"source","obj":"craft-sa-dev"},{"subj":"T576","pred":"source","obj":"craft-sa-dev"},{"subj":"T577","pred":"source","obj":"craft-sa-dev"},{"subj":"T578","pred":"source","obj":"craft-sa-dev"},{"subj":"T579","pred":"source","obj":"craft-sa-dev"},{"subj":"T580","pred":"source","obj":"craft-sa-dev"},{"subj":"T581","pred":"source","obj":"craft-sa-dev"},{"subj":"T584","pred":"source","obj":"craft-sa-dev"},{"subj":"T585","pred":"source","obj":"craft-sa-dev"},{"subj":"T586","pred":"source","obj":"craft-sa-dev"},{"subj":"T587","pred":"source","obj":"craft-sa-dev"},{"subj":"T588","pred":"source","obj":"craft-sa-dev"},{"subj":"T589","pred":"source","obj":"craft-sa-dev"},{"subj":"T590","pred":"source","obj":"craft-sa-dev"},{"subj":"T591","pred":"source","obj":"craft-sa-dev"},{"subj":"T592","pred":"source","obj":"craft-sa-dev"},{"subj":"T593","pred":"source","obj":"craft-sa-dev"},{"subj":"T594","pred":"source","obj":"craft-sa-dev"},{"subj":"T595","pred":"source","obj":"craft-sa-dev"},{"subj":"T596","pred":"source","obj":"craft-sa-dev"},{"subj":"T597","pred":"source","obj":"craft-sa-dev"},{"subj":"T598","pred":"source","obj":"craft-sa-dev"},{"subj":"T599","pred":"source","obj":"craft-sa-dev"},{"subj":"T600","pred":"source","obj":"craft-sa-dev"},{"subj":"T601","pred":"source","obj":"craft-sa-dev"},{"subj":"T602","pred":"source","obj":"craft-sa-dev"},{"subj":"T603","pred":"source","obj":"craft-sa-dev"},{"subj":"T604","pred":"source","obj":"craft-sa-dev"},{"subj":"T605","pred":"source","obj":"craft-sa-dev"},{"subj":"T606","pred":"source","obj":"craft-sa-dev"},{"subj":"T607","pred":"source","obj":"craft-sa-dev"},{"subj":"T608","pred":"source","obj":"craft-sa-dev"},{"subj":"T609","pred":"source","obj":"craft-sa-dev"},{"subj":"T610","pred":"source","obj":"craft-sa-dev"},{"subj":"T612","pred":"source","obj":"craft-sa-dev"},{"subj":"T613","pred":"source","obj":"craft-sa-dev"},{"subj":"T614","pred":"source","obj":"craft-sa-dev"},{"subj":"T615","pred":"source","obj":"craft-sa-dev"},{"subj":"T616","pred":"source","obj":"craft-sa-dev"},{"subj":"T617","pred":"source","obj":"craft-sa-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-ca-core-ex-dev","color":"#93a3ec","default":true},{"id":"craft-ca-core-dev","color":"#bdec93"},{"id":"craft-sa-dev","color":"#ec93d7"}]}]}}