PMC:1540739 / 17645-17855
Annnotations
craft-sa-dev
{"project":"craft-sa-dev","denotations":[{"id":"T12390","span":{"begin":0,"end":2},"obj":"IN"},{"id":"T12391","span":{"begin":3,"end":5},"obj":"NN"},{"id":"T12392","span":{"begin":6,"end":11},"obj":"NNS"},{"id":"T12393","span":{"begin":12,"end":15},"obj":"CC"},{"id":"T12394","span":{"begin":16,"end":22},"obj":"VBZ"},{"id":"T12395","span":{"begin":23,"end":31},"obj":"NN"},{"id":"T12396","span":{"begin":32,"end":44},"obj":"NN"},{"id":"T12397","span":{"begin":45,"end":47},"obj":"IN"},{"id":"T12398","span":{"begin":48,"end":49},"obj":"DT"},{"id":"T12399","span":{"begin":59,"end":67},"obj":"NN"},{"id":"T12400","span":{"begin":50,"end":58},"obj":"VBN"},{"id":"T12401","span":{"begin":68,"end":69},"obj":"-LRB-"},{"id":"T12402","span":{"begin":69,"end":72},"obj":"VB"},{"id":"T12403","span":{"begin":73,"end":79},"obj":"NN"},{"id":"T12404","span":{"begin":80,"end":81},"obj":"CD"},{"id":"T12405","span":{"begin":81,"end":83},"obj":","},{"id":"T12406","span":{"begin":83,"end":87},"obj":"NN"},{"id":"T12407","span":{"begin":88,"end":89},"obj":"NN"},{"id":"T12408","span":{"begin":89,"end":90},"obj":"-RRB-"},{"id":"T12409","span":{"begin":90,"end":91},"obj":"."},{"id":"T12411","span":{"begin":92,"end":94},"obj":"PRP"},{"id":"T12412","span":{"begin":100,"end":110},"obj":"VBD"},{"id":"T12413","span":{"begin":95,"end":99},"obj":"RB"},{"id":"T12414","span":{"begin":111,"end":118},"obj":"IN"},{"id":"T12415","span":{"begin":146,"end":150},"obj":"VBN"},{"id":"T12416","span":{"begin":119,"end":122},"obj":"DT"},{"id":"T12417","span":{"begin":128,"end":136},"obj":"NN"},{"id":"T12418","span":{"begin":123,"end":127},"obj":"NN"},{"id":"T12419","span":{"begin":137,"end":142},"obj":"MD"},{"id":"T12420","span":{"begin":143,"end":145},"obj":"VB"},{"id":"T12421","span":{"begin":151,"end":153},"obj":"TO"},{"id":"T12422","span":{"begin":154,"end":160},"obj":"VB"},{"id":"T12423","span":{"begin":161,"end":170},"obj":"NNS"},{"id":"T12424","span":{"begin":171,"end":173},"obj":"IN"},{"id":"T12425","span":{"begin":174,"end":177},"obj":"DT"},{"id":"T12426","span":{"begin":182,"end":188},"obj":"NN"},{"id":"T12427","span":{"begin":178,"end":181},"obj":"NN"},{"id":"T12428","span":{"begin":189,"end":191},"obj":"IN"},{"id":"T12429","span":{"begin":192,"end":199},"obj":"JJ"},{"id":"T12430","span":{"begin":200,"end":205},"obj":"NNS"},{"id":"T12431","span":{"begin":206,"end":207},"obj":"-LRB-"}],"relations":[{"id":"R3316","pred":"compound","subj":"T12391","obj":"T12392"},{"id":"R3318","pred":"pobj","subj":"T12392","obj":"T12390"},{"id":"R3322","pred":"compound","subj":"T12395","obj":"T12396"},{"id":"R3323","pred":"dobj","subj":"T12396","obj":"T12394"},{"id":"R3324","pred":"prep","subj":"T12397","obj":"T12396"},{"id":"R3326","pred":"det","subj":"T12398","obj":"T12399"},{"id":"R3327","pred":"pobj","subj":"T12399","obj":"T12397"},{"id":"R3329","pred":"amod","subj":"T12400","obj":"T12399"},{"id":"R3330","pred":"punct","subj":"T12401","obj":"T12402"},{"id":"R3331","pred":"parataxis","subj":"T12402","obj":"T12394"},{"id":"R3333","pred":"dobj","subj":"T12403","obj":"T12402"},{"id":"R3334","pred":"nummod","subj":"T12404","obj":"T12403"},{"id":"R3335","pred":"punct","subj":"T12405","obj":"T12403"},{"id":"R3337","pred":"compound","subj":"T12406","obj":"T12407"},{"id":"R3338","pred":"appos","subj":"T12407","obj":"T12403"},{"id":"R3340","pred":"punct","subj":"T12408","obj":"T12402"},{"id":"R3342","pred":"nsubj","subj":"T12411","obj":"T12412"},{"id":"R3344","pred":"advmod","subj":"T12413","obj":"T12412"},{"id":"R3345","pred":"mark","subj":"T12414","obj":"T12415"},{"id":"R3346","pred":"ccomp","subj":"T12415","obj":"T12412"},{"id":"R3348","pred":"det","subj":"T12416","obj":"T12417"},{"id":"R3349","pred":"nsubjpass","subj":"T12417","obj":"T12415"},{"id":"R3354","pred":"aux","subj":"T12421","obj":"T12422"},{"id":"R3360","pred":"det","subj":"T12425","obj":"T12426"},{"id":"R3362","pred":"compound","subj":"T12427","obj":"T12426"},{"id":"R3364","pred":"prep","subj":"T12428","obj":"T12423"},{"id":"R3365","pred":"amod","subj":"T12429","obj":"T12430"},{"id":"R3366","pred":"pobj","subj":"T12430","obj":"T12428"},{"id":"R3350","pred":"compound","subj":"T12418","obj":"T12417"},{"id":"R3352","pred":"aux","subj":"T12419","obj":"T12415"},{"id":"R3353","pred":"auxpass","subj":"T12420","obj":"T12415"},{"id":"R3356","pred":"advcl","subj":"T12422","obj":"T12415"},{"id":"R3357","pred":"dobj","subj":"T12423","obj":"T12422"},{"id":"R3358","pred":"prep","subj":"T12424","obj":"T12423"},{"id":"R3361","pred":"pobj","subj":"T12426","obj":"T12424"}],"text":"in ES cells and allows germline transmission of a targeted mutation (see Figure 1, path A).\nWe next determined whether the RMCE approach could be used to target mutations at the p53 allele in somatic cells (Fig"}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T11549","span":{"begin":3,"end":11},"obj":"CL:0002322"},{"id":"T11550","span":{"begin":6,"end":11},"obj":"CL_GO_EXT:cell"},{"id":"T11551","span":{"begin":59,"end":67},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T11552","span":{"begin":161,"end":170},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T11553","span":{"begin":178,"end":181},"obj":"PR_EXT:000003035"},{"id":"T11554","span":{"begin":182,"end":188},"obj":"SO_EXT:0001023"},{"id":"T11555","span":{"begin":192,"end":205},"obj":"CL:0002371"},{"id":"T11556","span":{"begin":200,"end":205},"obj":"CL_GO_EXT:cell"}],"text":"in ES cells and allows germline transmission of a targeted mutation (see Figure 1, path A).\nWe next determined whether the RMCE approach could be used to target mutations at the p53 allele in somatic cells (Fig"}
craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T11330","span":{"begin":3,"end":11},"obj":"CL:0002322"},{"id":"T11331","span":{"begin":178,"end":181},"obj":"PR:000003035"},{"id":"T11332","span":{"begin":182,"end":188},"obj":"SO:0001023"},{"id":"T11333","span":{"begin":192,"end":205},"obj":"CL:0002371"}],"text":"in ES cells and allows germline transmission of a targeted mutation (see Figure 1, path A).\nWe next determined whether the RMCE approach could be used to target mutations at the p53 allele in somatic cells (Fig"}