PMC:1540739 / 1384-1629 JSONTXT

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    craft-sa-dev

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    craft-ca-core-ex-dev

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    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T2338","span":{"begin":87,"end":90},"obj":"PR:000003035"},{"id":"T2339","span":{"begin":131,"end":140},"obj":"UBERON:0000922"},{"id":"T2340","span":{"begin":131,"end":145},"obj":"_FRAGMENT"},{"id":"T2341","span":{"begin":151,"end":156},"obj":"CL:0002322"},{"id":"T2342","span":{"begin":147,"end":149},"obj":"_FRAGMENT"},{"id":"T2343","span":{"begin":176,"end":180},"obj":"NCBITaxon:10088"}],"relations":[{"id":"R196","pred":"_lexicallyChainedTo","subj":"T2341","obj":"T2340"},{"id":"R197","pred":"_lexicallyChainedTo","subj":"T2341","obj":"T2342"}],"text":"t years, some of these models were tested in vivo by targeting subtle mutations at the p53 locus using homologous recombination in embryonic stem (ES) cells to generate mutant mice. The strength of this approach is that mutations are tested in a"}