PMC:1540739 / 1310-1634
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2588 | 14-25 | VBN | denotes | established |
T2602 | 0-7 | NNS | denotes | mutants |
T2604 | 7-9 | , | denotes | , |
T2605 | 9-13 | VBD | denotes | have |
T2606 | 26-32 | NNS | denotes | models |
T2607 | 33-35 | TO | denotes | to |
T2608 | 36-43 | VB | denotes | explain |
T2609 | 44-47 | WRB | denotes | how |
T2610 | 55-64 | VBN | denotes | regulated |
T2611 | 48-51 | NN | denotes | p53 |
T2612 | 52-54 | VBZ | denotes | is |
T2613 | 64-65 | . | denotes | . |
T2614 | 65-255 | sentence | denotes | In recent years, some of these models were tested in vivo by targeting subtle mutations at the p53 locus using homologous recombination in embryonic stem (ES) cells to generate mutant mice. |
T2615 | 66-68 | IN | denotes | In |
T2616 | 109-115 | VBN | denotes | tested |
T2617 | 69-75 | JJ | denotes | recent |
T2618 | 76-81 | NNS | denotes | years |
T2619 | 81-83 | , | denotes | , |
T2620 | 83-87 | DT | denotes | some |
T2621 | 88-90 | IN | denotes | of |
T2622 | 91-96 | DT | denotes | these |
T2623 | 97-103 | NNS | denotes | models |
T2624 | 104-108 | VBD | denotes | were |
T2625 | 116-118 | FW | denotes | in |
T2626 | 119-123 | FW | denotes | vivo |
T2627 | 124-126 | IN | denotes | by |
T2628 | 127-136 | VBG | denotes | targeting |
T2629 | 137-143 | JJ | denotes | subtle |
T2630 | 144-153 | NNS | denotes | mutations |
T2631 | 154-156 | IN | denotes | at |
T2632 | 157-160 | DT | denotes | the |
T2633 | 165-170 | NN | denotes | locus |
T2634 | 161-164 | NN | denotes | p53 |
T2635 | 171-176 | VBG | denotes | using |
T2636 | 177-187 | JJ | denotes | homologous |
T2637 | 188-201 | NN | denotes | recombination |
T2638 | 202-204 | IN | denotes | in |
T2639 | 205-214 | JJ | denotes | embryonic |
T2640 | 215-219 | NN | denotes | stem |
T2641 | 225-230 | NNS | denotes | cells |
T2642 | 220-221 | -LRB- | denotes | ( |
T2643 | 221-223 | NN | denotes | ES |
T2644 | 223-224 | -RRB- | denotes | ) |
T2645 | 231-233 | TO | denotes | to |
T2646 | 234-242 | VB | denotes | generate |
T2647 | 243-249 | JJ | denotes | mutant |
T2648 | 250-254 | NNS | denotes | mice |
T2649 | 254-255 | . | denotes | . |
T2651 | 256-259 | DT | denotes | The |
T2652 | 260-268 | NN | denotes | strength |
T2653 | 286-288 | VBZ | denotes | is |
T2654 | 269-271 | IN | denotes | of |
T2655 | 272-276 | DT | denotes | this |
T2656 | 277-285 | NN | denotes | approach |
T2657 | 289-293 | IN | denotes | that |
T2658 | 308-314 | VBN | denotes | tested |
T2659 | 294-303 | NNS | denotes | mutations |
T2660 | 304-307 | VBP | denotes | are |
T2661 | 315-317 | IN | denotes | in |
T2662 | 318-319 | DT | denotes | a |
R234 | T2604 | T2588 | punct | ", ",established |
R235 | T2605 | T2588 | aux | have,established |
R236 | T2606 | T2588 | dobj | models,established |
R237 | T2607 | T2608 | aux | to,explain |
R238 | T2608 | T2606 | advcl | explain,models |
R239 | T2609 | T2610 | advmod | how,regulated |
R240 | T2610 | T2608 | ccomp | regulated,explain |
R241 | T2611 | T2610 | nsubjpass | p53,regulated |
R242 | T2612 | T2610 | auxpass | is,regulated |
R243 | T2613 | T2588 | punct | .,established |
R244 | T2615 | T2616 | prep | In,tested |
R245 | T2617 | T2618 | amod | recent,years |
R246 | T2618 | T2615 | pobj | years,In |
R247 | T2619 | T2616 | punct | ", ",tested |
R248 | T2620 | T2616 | nsubjpass | some,tested |
R249 | T2621 | T2620 | prep | of,some |
R250 | T2622 | T2623 | det | these,models |
R251 | T2623 | T2621 | pobj | models,of |
R252 | T2624 | T2616 | auxpass | were,tested |
R253 | T2625 | T2626 | advmod | in,vivo |
R254 | T2626 | T2616 | advmod | vivo,tested |
R255 | T2627 | T2616 | prep | by,tested |
R256 | T2628 | T2627 | pcomp | targeting,by |
R257 | T2629 | T2630 | amod | subtle,mutations |
R258 | T2630 | T2628 | dobj | mutations,targeting |
R259 | T2631 | T2628 | prep | at,targeting |
R260 | T2632 | T2633 | det | the,locus |
R261 | T2633 | T2631 | pobj | locus,at |
R263 | T2634 | T2633 | compound | p53,locus |
R265 | T2635 | T2628 | advcl | using,targeting |
R268 | T2636 | T2637 | amod | homologous,recombination |
R270 | T2637 | T2635 | dobj | recombination,using |
R274 | T2638 | T2635 | prep | in,using |
R277 | T2639 | T2640 | amod | embryonic,stem |
R281 | T2640 | T2641 | nmod | stem,cells |
R283 | T2641 | T2638 | pobj | cells,in |
R285 | T2642 | T2640 | punct | (,stem |
R288 | T2643 | T2640 | appos | ES,stem |
R293 | T2644 | T2641 | punct | ),cells |
R296 | T2645 | T2646 | aux | to,generate |
R303 | T2646 | T2635 | advcl | generate,using |
R305 | T2647 | T2648 | amod | mutant,mice |
R311 | T2648 | T2646 | dobj | mice,generate |
R313 | T2649 | T2616 | punct | .,tested |
R316 | T2651 | T2652 | det | The,strength |
R318 | T2652 | T2653 | nsubj | strength,is |
R321 | T2654 | T2652 | prep | of,strength |
R325 | T2655 | T2656 | det | this,approach |
R330 | T2656 | T2654 | pobj | approach,of |
R334 | T2657 | T2658 | mark | that,tested |
R337 | T2658 | T2653 | ccomp | tested,is |
R341 | T2659 | T2658 | nsubj | mutations,tested |
R346 | T2660 | T2658 | aux | are,tested |
R350 | T2661 | T2658 | prep | in,tested |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2422 | 0-7 | SO_EXT:sequence_altered_entity | denotes | mutants |
T2423 | 48-51 | PR_EXT:000003035 | denotes | p53 |
T2424 | 55-64 | GO:0065007 | denotes | regulated |
T2425 | 144-153 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
T2426 | 161-164 | PR_EXT:000003035 | denotes | p53 |
T2427 | 188-201 | GO_SO_EXT:sequence_rearrangement_process | denotes | recombination |
T2428 | 205-214 | UBERON:0000922 | denotes | embryonic |
T2429 | 205-219 | _FRAGMENT | denotes | embryonic stem |
T2430 | 225-230 | CL:0002322 | denotes | cells |
T2431 | 221-223 | _FRAGMENT | denotes | ES |
T2432 | 225-230 | CL_GO_EXT:cell | denotes | cells |
T2433 | 243-249 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T2434 | 250-254 | NCBITaxon:10088 | denotes | mice |
T2435 | 294-303 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
R200 | T2430 | T2429 | _lexicallyChainedTo | cells,embryonic stem |
R201 | T2430 | T2431 | _lexicallyChainedTo | cells,ES |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2336 | 48-51 | PR:000003035 | denotes | p53 |
T2337 | 55-64 | GO:0065007 | denotes | regulated |
T2338 | 161-164 | PR:000003035 | denotes | p53 |
T2339 | 205-214 | UBERON:0000922 | denotes | embryonic |
T2340 | 205-219 | _FRAGMENT | denotes | embryonic stem |
T2341 | 225-230 | CL:0002322 | denotes | cells |
T2342 | 221-223 | _FRAGMENT | denotes | ES |
T2343 | 250-254 | NCBITaxon:10088 | denotes | mice |
R196 | T2341 | T2340 | _lexicallyChainedTo | cells,embryonic stem |
R197 | T2341 | T2342 | _lexicallyChainedTo | cells,ES |