| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T5692 |
3241-3242 |
CD |
denotes |
8 |
| T5691 |
3238-3240 |
IN |
denotes |
of |
| T5690 |
3233-3237 |
NN |
denotes |
apex |
| T5689 |
3229-3232 |
DT |
denotes |
the |
| T5688 |
3226-3228 |
IN |
denotes |
in |
| T5687 |
3210-3217 |
JJ |
denotes |
sensory |
| T5686 |
3203-3209 |
JJ |
denotes |
spiral |
| T5685 |
3194-3202 |
JJ |
denotes |
numerous |
| T5684 |
3218-3225 |
NNS |
denotes |
neurons |
| T5683 |
3190-3193 |
DT |
denotes |
the |
| T5682 |
3177-3181 |
JJ |
denotes |
null |
| T5681 |
3182-3189 |
NNS |
denotes |
mutants |
| T5680 |
3171-3176 |
NN |
denotes |
Brn3c |
| T5679 |
3168-3170 |
IN |
denotes |
in |
| T5678 |
3154-3158 |
RB |
denotes |
even |
| T5677 |
3150-3153 |
MD |
denotes |
may |
| T5676 |
3141-3149 |
NNS |
denotes |
neonates |
| T5675 |
3137-3140 |
CC |
denotes |
and |
| T5674 |
3129-3136 |
NNS |
denotes |
embryos |
| T5673 |
3126-3128 |
IN |
denotes |
in |
| T5672 |
3120-3125 |
NNS |
denotes |
cells |
| T5671 |
3109-3119 |
VBG |
denotes |
supporting |
| T5670 |
3106-3108 |
IN |
denotes |
in |
| T5669 |
3104-3105 |
CD |
denotes |
3 |
| T5668 |
3103-3104 |
HYPH |
denotes |
- |
| T5667 |
3101-3103 |
NN |
denotes |
NT |
| T5666 |
3098-3100 |
IN |
denotes |
of |
| T5665 |
3159-3167 |
VB |
denotes |
preserve |
| T5664 |
3087-3097 |
NN |
denotes |
expression |
| T5663 |
3082-3086 |
DT |
denotes |
This |
| T5662 |
3081-3272 |
sentence |
denotes |
This expression of NT-3 in supporting cells in embryos and neonates may even preserve in Brn3c null mutants the numerous spiral sensory neurons in the apex of 8-day old animals (Figs. 3, 4). |
| T5661 |
3080-3081 |
. |
denotes |
. |
| T5660 |
3079-3080 |
-RRB- |
denotes |
] |
| T5659 |
3078-3079 |
CD |
denotes |
6 |
| T5658 |
3077-3078 |
-LRB- |
denotes |
[ |
| T5657 |
3071-3076 |
NNS |
denotes |
cells |
| T5656 |
3060-3070 |
VBG |
denotes |
supporting |
| T5655 |
3057-3059 |
IN |
denotes |
in |
| T5654 |
3033-3046 |
RB |
denotes |
predominantly |
| T5653 |
3030-3032 |
VBZ |
denotes |
is |
| T5652 |
3028-3029 |
CD |
denotes |
3 |
| T5651 |
3027-3028 |
HYPH |
denotes |
- |
| T5650 |
3025-3027 |
NN |
denotes |
NT |
| T5649 |
3023-3025 |
, |
denotes |
, |
| T5648 |
3016-3023 |
NNS |
denotes |
embryos |
| T5647 |
3013-3015 |
IN |
denotes |
of |
| T5646 |
3005-3012 |
NN |
denotes |
utricle |
| T5645 |
3001-3004 |
CC |
denotes |
and |
| T5644 |
2993-3000 |
NN |
denotes |
saccule |
| T5643 |
2989-2992 |
DT |
denotes |
the |
| T5642 |
2986-2988 |
IN |
denotes |
in |
| T5641 |
2978-2982 |
RB |
denotes |
well |
| T5640 |
2983-2985 |
IN |
denotes |
as |
| T5639 |
2975-2977 |
RB |
denotes |
as |
| T5638 |
2966-2974 |
NNS |
denotes |
neonates |
| T5637 |
2962-2965 |
CC |
denotes |
and |
| T5636 |
2954-2961 |
NNS |
denotes |
embryos |
| T5635 |
2951-2953 |
IN |
denotes |
of |
| T5634 |
2943-2950 |
NN |
denotes |
cochlea |
| T5633 |
2939-2942 |
DT |
denotes |
the |
| T5632 |
2936-2938 |
IN |
denotes |
in |
| T5631 |
2934-2936 |
, |
denotes |
, |
| T5630 |
2930-2934 |
NN |
denotes |
fact |
| T5629 |
3047-3056 |
VBN |
denotes |
expressed |
| T5628 |
2927-2929 |
IN |
denotes |
In |
| T5627 |
2926-3081 |
sentence |
denotes |
In fact, in the cochlea of embryos and neonates as well as in the saccule and utricle of embryos, NT-3 is predominantly expressed in supporting cells [6]. |
| T5626 |
2925-2926 |
. |
denotes |
. |
| T5625 |
2918-2925 |
NN |
denotes |
cochlea |
| T5624 |
2914-2917 |
DT |
denotes |
the |
| T5623 |
2911-2913 |
IN |
denotes |
of |
| T5622 |
2906-2910 |
NN |
denotes |
apex |
| T5621 |
2902-2905 |
DT |
denotes |
the |
| T5620 |
2899-2901 |
IN |
denotes |
in |
| T5619 |
2891-2898 |
JJ |
denotes |
obvious |
| T5618 |
2878-2890 |
RB |
denotes |
particularly |
| T5617 |
2875-2877 |
VBZ |
denotes |
is |
| T5616 |
2868-2874 |
JJ |
denotes |
latter |
| T5615 |
2864-2867 |
DT |
denotes |
The |
| T5614 |
2863-2926 |
sentence |
denotes |
The latter is particularly obvious in the apex of the cochlea. |
| T5613 |
2862-2863 |
. |
denotes |
. |
| T5612 |
2861-2862 |
-RRB- |
denotes |
) |
| T5611 |
2858-2860 |
, |
denotes |
, |
| T5610 |
2857-2858 |
CD |
denotes |
8 |
| T5609 |
2851-2856 |
NNS |
denotes |
Figs. |
| T5608 |
2860-2861 |
CD |
denotes |
9 |
| T5607 |
2850-2851 |
-LRB- |
denotes |
( |
| T5606 |
2838-2849 |
NNS |
denotes |
littermates |
| T5605 |
2830-2837 |
NN |
denotes |
control |
| T5604 |
2827-2829 |
IN |
denotes |
in |
| T5603 |
2821-2826 |
DT |
denotes |
those |
| T5602 |
2816-2820 |
IN |
denotes |
from |
| T5601 |
2802-2808 |
RB |
denotes |
hardly |
| T5600 |
2789-2790 |
CD |
denotes |
3 |
| T5599 |
2788-2789 |
HYPH |
denotes |
- |
| T5598 |
2791-2801 |
NN |
denotes |
expression |
| T5597 |
2786-2788 |
NN |
denotes |
NT |
| T5596 |
2783-2785 |
IN |
denotes |
of |
| T5595 |
2776-2782 |
NNS |
denotes |
levels |
| T5594 |
2772-2775 |
DT |
denotes |
the |
| T5593 |
2809-2815 |
VBP |
denotes |
differ |
| T5592 |
2767-2771 |
IN |
denotes |
that |
| T5591 |
2756-2758 |
PRP |
denotes |
it |
| T5590 |
2754-2756 |
, |
denotes |
, |
| T5589 |
2750-2754 |
NN |
denotes |
fact |
| T5588 |
2759-2766 |
VBZ |
denotes |
appears |
| T5587 |
2747-2749 |
IN |
denotes |
In |
| T5586 |
2746-2863 |
sentence |
denotes |
In fact, it appears that the levels of NT-3 expression hardly differ from those in control littermates (Figs. 8, 9). |
| T5585 |
2745-2746 |
. |
denotes |
. |
| T5584 |
2744-2745 |
-RRB- |
denotes |
] |
| T5583 |
2742-2743 |
, |
denotes |
, |
| T5582 |
2741-2742 |
CD |
denotes |
6 |
| T5581 |
2743-2744 |
CD |
denotes |
7 |
| T5580 |
2740-2741 |
-LRB- |
denotes |
[ |
| T5579 |
2726-2729 |
VBP |
denotes |
are |
| T5578 |
2724-2725 |
CD |
denotes |
3 |
| T5577 |
2723-2724 |
HYPH |
denotes |
- |
| T5576 |
2721-2723 |
NN |
denotes |
NT |
| T5575 |
2717-2720 |
CC |
denotes |
and |
| T5574 |
2712-2716 |
NN |
denotes |
BDNF |
| T5573 |
2707-2711 |
CC |
denotes |
both |
| T5572 |
2730-2739 |
VBN |
denotes |
expressed |
| T5571 |
2704-2706 |
IN |
denotes |
as |
| T5570 |
2698-2703 |
JJ |
denotes |
clear |
| T5569 |
2693-2697 |
RBR |
denotes |
less |
| T5568 |
2682-2689 |
NN |
denotes |
cochlea |
| T5567 |
2678-2681 |
CC |
denotes |
and |
| T5566 |
2670-2677 |
NN |
denotes |
saccule |
| T5565 |
2668-2670 |
, |
denotes |
, |
| T5564 |
2661-2668 |
NN |
denotes |
utricle |
| T5563 |
2657-2660 |
DT |
denotes |
the |
| T5562 |
2654-2656 |
IN |
denotes |
in |
| T5561 |
2690-2692 |
VBZ |
denotes |
is |
| T5560 |
2644-2653 |
NN |
denotes |
situation |
| T5559 |
2640-2643 |
DT |
denotes |
The |
| T5558 |
2639-2746 |
sentence |
denotes |
The situation in the utricle, saccule and cochlea is less clear as both BDNF and NT-3 are expressed [6,7]. |
| T5557 |
2638-2639 |
. |
denotes |
. |
| T5556 |
2637-2638 |
-RRB- |
denotes |
) |
| T5555 |
2634-2636 |
, |
denotes |
, |
| T5554 |
2633-2634 |
CD |
denotes |
2 |
| T5553 |
2627-2632 |
NNS |
denotes |
Figs. |
| T5552 |
2636-2637 |
CD |
denotes |
3 |
| T5551 |
2626-2627 |
-LRB- |
denotes |
( |
| T5550 |
2620-2625 |
RB |
denotes |
later |
| T5549 |
2616-2619 |
CC |
denotes |
and |
| T5548 |
2610-2615 |
NN |
denotes |
birth |
| T5547 |
2607-2609 |
IN |
denotes |
at |
| T5546 |
2597-2606 |
NNS |
denotes |
efferents |
| T5545 |
2593-2596 |
CC |
denotes |
and |
| T5544 |
2583-2592 |
NNS |
denotes |
afferents |
| T5543 |
2578-2582 |
CC |
denotes |
both |
| T5542 |
2575-2577 |
IN |
denotes |
by |
| T5541 |
2563-2574 |
NN |
denotes |
innervation |
| T5540 |
2560-2562 |
DT |
denotes |
an |
| T5539 |
2534-2541 |
JJ |
denotes |
sensory |
| T5538 |
2528-2533 |
JJ |
denotes |
canal |
| T5537 |
2542-2551 |
NNS |
denotes |
epithelia |
| T5536 |
2524-2527 |
DT |
denotes |
all |
| T5535 |
2552-2559 |
VBP |
denotes |
receive |
| T5534 |
2519-2523 |
IN |
denotes |
that |
| T5533 |
2514-2518 |
NN |
denotes |
fact |
| T5532 |
2510-2513 |
DT |
denotes |
the |
| T5531 |
2505-2509 |
IN |
denotes |
from |
| T5530 |
2499-2504 |
JJ |
denotes |
clear |
| T5529 |
2484-2495 |
JJ |
denotes |
significant |
| T5528 |
2496-2498 |
VBZ |
denotes |
is |
| T5527 |
2469-2479 |
NN |
denotes |
expression |
| T5526 |
2466-2468 |
IN |
denotes |
of |
| T5525 |
2455-2458 |
JJ |
denotes |
low |
| T5524 |
2449-2454 |
DT |
denotes |
these |
| T5523 |
2459-2465 |
NNS |
denotes |
levels |
| T5522 |
2444-2448 |
RB |
denotes |
even |
| T5521 |
2480-2483 |
VBP |
denotes |
are |
| T5520 |
2439-2443 |
IN |
denotes |
That |
| T5519 |
2438-2639 |
sentence |
denotes |
That even these low levels of expression are significant is clear from the fact that all canal sensory epithelia receive an innervation by both afferents and efferents at birth and later (Figs. 2, 3). |
| T5518 |
2437-2438 |
. |
denotes |
. |
| T5517 |
2436-2437 |
-RRB- |
denotes |
] |
| T5516 |
2433-2434 |
, |
denotes |
, |
| T5515 |
2432-2433 |
CD |
denotes |
6 |
| T5514 |
2434-2436 |
CD |
denotes |
13 |
| T5513 |
2431-2432 |
-LRB- |
denotes |
[ |
| T5512 |
2425-2430 |
NN |
denotes |
birth |
| T5511 |
2418-2424 |
IN |
denotes |
before |
| T5510 |
2410-2412 |
VBZ |
denotes |
is |
| T5509 |
2402-2409 |
NNS |
denotes |
cristae |
| T5508 |
2396-2401 |
JJ |
denotes |
canal |
| T5507 |
2393-2395 |
IN |
denotes |
to |
| T5506 |
2381-2392 |
NN |
denotes |
innervation |
| T5505 |
2376-2380 |
DT |
denotes |
this |
| T5504 |
2363-2367 |
JJ |
denotes |
null |
| T5503 |
2358-2362 |
NN |
denotes |
trkB |
| T5502 |
2354-2357 |
CC |
denotes |
and |
| T5501 |
2368-2375 |
NNS |
denotes |
mutants |
| T5500 |
2349-2353 |
NN |
denotes |
BDNF |
| T5499 |
2346-2348 |
IN |
denotes |
in |
| T5498 |
2413-2417 |
VBN |
denotes |
lost |
| T5497 |
2341-2345 |
IN |
denotes |
that |
| T5496 |
2331-2334 |
VBZ |
denotes |
has |
| T5495 |
2335-2340 |
VBN |
denotes |
shown |
| T5494 |
2322-2330 |
NN |
denotes |
research |
| T5493 |
2317-2321 |
NN |
denotes |
Past |
| T5492 |
2316-2438 |
sentence |
denotes |
Past research has shown that in BDNF and trkB null mutants this innervation to canal cristae is lost before birth [6,13]. |
| T5491 |
2315-2316 |
. |
denotes |
. |
| T5490 |
2314-2315 |
-RRB- |
denotes |
) |
| T5489 |
2313-2314 |
CD |
denotes |
8 |
| T5488 |
2308-2312 |
NN |
denotes |
Fig. |
| T5487 |
2307-2308 |
-LRB- |
denotes |
( |
| T5486 |
2293-2298 |
NN |
denotes |
canal |
| T5485 |
2299-2306 |
NNS |
denotes |
cristae |
| T5484 |
2289-2292 |
DT |
denotes |
the |
| T5483 |
2286-2288 |
IN |
denotes |
in |
| T5482 |
2281-2285 |
NN |
denotes |
case |
| T5481 |
2277-2280 |
DT |
denotes |
the |
| T5480 |
2274-2276 |
VBZ |
denotes |
is |
| T5479 |
2271-2273 |
IN |
denotes |
as |
| T5478 |
2269-2271 |
, |
denotes |
, |
| T5476 |
2262-2264 |
IN |
denotes |
of |
| T5475 |
2243-2250 |
JJ |
denotes |
limited |
| T5474 |
2251-2261 |
NN |
denotes |
expression |
| T5473 |
2238-2242 |
RB |
denotes |
only |
| T5472 |
2235-2237 |
IN |
denotes |
by |
| T5471 |
2220-2222 |
VB |
denotes |
be |
| T5470 |
2223-2234 |
VBN |
denotes |
accompanied |
| T5469 |
2217-2219 |
TO |
denotes |
to |
| T5468 |
2203-2208 |
NNS |
denotes |
cells |
| T5467 |
2198-2202 |
NN |
denotes |
hair |
| T5466 |
2195-2197 |
IN |
denotes |
of |
| T5465 |
2179-2194 |
NN |
denotes |
differentiation |
| T5464 |
2170-2178 |
JJ |
denotes |
terminal |
| T5463 |
2167-2169 |
IN |
denotes |
of |
| T5462 |
2162-2166 |
NN |
denotes |
lack |
| T5461 |
2158-2161 |
DT |
denotes |
the |
| T5460 |
2156-2158 |
, |
denotes |
, |
| T5459 |
2155-2156 |
-RRB- |
denotes |
] |
| T5458 |
2152-2153 |
, |
denotes |
, |
| T5457 |
2151-2152 |
CD |
denotes |
7 |
| T5456 |
2150-2151 |
, |
denotes |
, |
| T5455 |
2149-2150 |
CD |
denotes |
6 |
| T5454 |
2153-2155 |
CD |
denotes |
20 |
| T5453 |
2148-2149 |
-LRB- |
denotes |
[ |
| T5452 |
2142-2147 |
NNS |
denotes |
cells |
| T5451 |
2137-2141 |
NN |
denotes |
hair |
| T5450 |
2134-2136 |
IN |
denotes |
by |
| T5449 |
2113-2124 |
RB |
denotes |
exclusively |
| T5448 |
2110-2112 |
VB |
denotes |
be |
| T5447 |
2125-2133 |
VBN |
denotes |
produced |
| T5703 |
3271-3272 |
. |
denotes |
. |
| T5702 |
3270-3271 |
-RRB- |
denotes |
) |
| T5701 |
3267-3269 |
, |
denotes |
, |
| T5700 |
3266-3267 |
CD |
denotes |
3 |
| T5699 |
3260-3265 |
NNS |
denotes |
Figs. |
| T5698 |
3269-3270 |
CD |
denotes |
4 |
| T5697 |
3259-3260 |
-LRB- |
denotes |
( |
| T5696 |
3251-3258 |
NNS |
denotes |
animals |
| T5695 |
3247-3250 |
JJ |
denotes |
old |
| T5694 |
3242-3243 |
HYPH |
denotes |
- |
| T5446 |
2107-2109 |
TO |
denotes |
to |
| T5445 |
2209-2216 |
VBZ |
denotes |
appears |
| T5444 |
2094-2098 |
NN |
denotes |
BDNF |
| T5443 |
2099-2106 |
VBZ |
denotes |
appears |
| T5442 |
2088-2093 |
IN |
denotes |
Since |
| T5441 |
2087-2316 |
sentence |
denotes |
Since BDNF appears to be exclusively produced by hair cells [6,7,20], the lack of terminal differentiation of hair cells appears to be accompanied by only limited expression of BDNF, as is the case in the canal cristae (Fig. 8). |
| T5440 |
2086-2087 |
. |
denotes |
. |
| T5439 |
2074-2078 |
JJ |
denotes |
null |
| T5438 |
2068-2073 |
NN |
denotes |
Brn3c |
| T5437 |
2079-2086 |
NNS |
denotes |
mutants |
| T5436 |
2060-2067 |
JJ |
denotes |
newborn |
| T5435 |
2057-2059 |
IN |
denotes |
in |
| T5434 |
2045-2056 |
NN |
denotes |
innervation |
| T5433 |
2036-2044 |
JJ |
denotes |
cochlear |
| T5432 |
2033-2035 |
IN |
denotes |
of |
| T5431 |
2014-2020 |
JJ |
denotes |
normal |
| T5430 |
2021-2032 |
NN |
denotes |
development |
| T5429 |
2010-2013 |
DT |
denotes |
the |
| T5428 |
2005-2009 |
IN |
denotes |
with |
| T5427 |
1995-2004 |
NN |
denotes |
agreement |
| T5426 |
1992-1994 |
IN |
denotes |
in |
| T5425 |
1987-1989 |
, |
denotes |
, |
| T5424 |
1986-1987 |
-RRB- |
denotes |
] |
| T5423 |
1983-1984 |
, |
denotes |
, |
| T5422 |
1982-1983 |
CD |
denotes |
9 |
| T5421 |
1981-1982 |
, |
denotes |
, |
| T5420 |
1980-1981 |
CD |
denotes |
6 |
| T5419 |
1984-1986 |
CD |
denotes |
14 |
| T5418 |
1979-1980 |
-LRB- |
denotes |
[ |
| T5417 |
1963-1970 |
JJ |
denotes |
sensory |
| T5416 |
1971-1978 |
NNS |
denotes |
neurons |
| T5415 |
1956-1962 |
JJ |
denotes |
spiral |
| T5414 |
1945-1955 |
VBG |
denotes |
supporting |
| T5413 |
1933-1944 |
RB |
denotes |
prominently |
| T5412 |
1928-1932 |
RBS |
denotes |
most |
| T5411 |
1915-1927 |
NN |
denotes |
neurotrophin |
| T5410 |
1911-1914 |
DT |
denotes |
the |
| T5409 |
1908-1910 |
VB |
denotes |
be |
| T5408 |
1905-1907 |
TO |
denotes |
to |
| T5407 |
1894-1898 |
VBN |
denotes |
been |
| T5406 |
1890-1893 |
VBZ |
denotes |
has |
| T5405 |
1899-1904 |
VBN |
denotes |
shown |
| T5404 |
1884-1889 |
WDT |
denotes |
which |
| T5403 |
1882-1884 |
, |
denotes |
, |
| T5402 |
1868-1874 |
JJ |
denotes |
mutant |
| T5401 |
1863-1867 |
JJ |
denotes |
null |
| T5400 |
1875-1882 |
NN |
denotes |
cochlea |
| T5399 |
1857-1862 |
NN |
denotes |
Brn3c |
| T5398 |
1854-1856 |
IN |
denotes |
in |
| T5397 |
1841-1842 |
CD |
denotes |
3 |
| T5396 |
1840-1841 |
HYPH |
denotes |
- |
| T5395 |
1843-1853 |
NN |
denotes |
expression |
| T5394 |
1838-1840 |
NN |
denotes |
NT |
| T5393 |
1835-1837 |
IN |
denotes |
of |
| T5392 |
1989-1991 |
VBZ |
denotes |
is |
| T5391 |
1824-1828 |
JJ |
denotes |
high |
| T5390 |
1810-1823 |
RB |
denotes |
comparatively |
| T5389 |
1829-1834 |
NN |
denotes |
level |
| T5388 |
1806-1809 |
DT |
denotes |
The |
| T5387 |
1805-2087 |
sentence |
denotes |
The comparatively high level of NT-3 expression in Brn3c null mutant cochlea, which has been shown to be the neurotrophin most prominently supporting spiral sensory neurons [6,9,14], is in agreement with the normal development of cochlear innervation in newborn Brn3c null mutants. |
| T5386 |
1804-1805 |
. |
denotes |
. |
| T5385 |
1802-1804 |
NN |
denotes |
P0 |
| T5384 |
1796-1801 |
IN |
denotes |
until |
| T5383 |
1776-1783 |
VBN |
denotes |
limited |
| T5382 |
1784-1795 |
NN |
denotes |
maintenance |
| T5381 |
1774-1775 |
DT |
denotes |
a |
| T5380 |
1770-1773 |
CC |
denotes |
and |
| T5379 |
1754-1759 |
NN |
denotes |
fiber |
| T5378 |
1760-1769 |
NN |
denotes |
outgrowth |
| T5377 |
1747-1753 |
JJ |
denotes |
normal |
| T5376 |
1735-1738 |
MD |
denotes |
can |
| T5375 |
1717-1724 |
JJ |
denotes |
sensory |
| T5374 |
1706-1716 |
JJ |
denotes |
vestibular |
| T5373 |
1725-1734 |
NNS |
denotes |
epithelia |
| T5372 |
1702-1705 |
DT |
denotes |
the |
| T5371 |
1699-1701 |
IN |
denotes |
in |
| T5370 |
1685-1698 |
NNS |
denotes |
neurotrophins |
| T5369 |
1682-1684 |
IN |
denotes |
of |
| T5368 |
1671-1674 |
JJ |
denotes |
low |
| T5367 |
1665-1670 |
DT |
denotes |
these |
| T5366 |
1675-1681 |
NNS |
denotes |
levels |
| T5365 |
1660-1664 |
RB |
denotes |
even |
| T5364 |
1739-1746 |
VB |
denotes |
sustain |
| T5363 |
1655-1659 |
IN |
denotes |
that |
| T5362 |
1647-1654 |
VBZ |
denotes |
appears |
| T5361 |
1644-1646 |
PRP |
denotes |
It |
| T5360 |
1643-1805 |
sentence |
denotes |
It appears that even these low levels of neurotrophins in the vestibular sensory epithelia can sustain normal fiber outgrowth and a limited maintenance until P0. |
| T5359 |
1642-1643 |
. |
denotes |
. |
| T5358 |
1630-1634 |
JJ |
denotes |
null |
| T5357 |
1624-1629 |
NN |
denotes |
Brn3c |
| T5356 |
1635-1642 |
NNS |
denotes |
mutants |
| T5355 |
1614-1623 |
JJ |
denotes |
embryonic |
| T5354 |
1611-1613 |
IN |
denotes |
in |
| T5353 |
1593-1600 |
JJ |
denotes |
sensory |
| T5352 |
1601-1610 |
NNS |
denotes |
epithelia |
| T5351 |
1589-1592 |
DT |
denotes |
all |
| T5350 |
1586-1588 |
IN |
denotes |
in |
| T5349 |
1565-1575 |
RB |
denotes |
apparently |
| T5348 |
1561-1564 |
VBP |
denotes |
are |
| T5347 |
1547-1560 |
NNS |
denotes |
neurotrophins |
| T5346 |
1544-1546 |
IN |
denotes |
of |
| T5345 |
1533-1536 |
JJ |
denotes |
low |
| T5344 |
1508-1520 |
RB |
denotes |
biologically |
| T5343 |
1521-1532 |
JJ |
denotes |
significant |
| T5342 |
1497-1507 |
RB |
denotes |
apparently |
| T5341 |
1495-1497 |
, |
denotes |
, |
| T5340 |
1537-1543 |
NNS |
denotes |
levels |
| T5339 |
1491-1495 |
DT |
denotes |
some |
| T5338 |
1489-1491 |
, |
denotes |
, |
| T5337 |
1480-1489 |
NN |
denotes |
reduction |
| T5336 |
1475-1479 |
DT |
denotes |
this |
| T5335 |
1576-1585 |
VBN |
denotes |
expressed |
| T5334 |
1467-1474 |
IN |
denotes |
Despite |
| T5333 |
1466-1643 |
sentence |
denotes |
Despite this reduction, some, apparently biologically significant low levels of neurotrophins are apparently expressed in all sensory epithelia in embryonic Brn3c null mutants. |
| T5332 |
1465-1466 |
. |
denotes |
. |
| T5331 |
1464-1465 |
-RRB- |
denotes |
) |
| T5330 |
1461-1463 |
, |
denotes |
, |
| T5329 |
1460-1461 |
CD |
denotes |
8 |
| T5328 |
1454-1459 |
NNS |
denotes |
Figs. |
| T5327 |
1463-1464 |
CD |
denotes |
9 |
| T5326 |
1453-1454 |
-LRB- |
denotes |
( |
| T5325 |
1448-1452 |
NN |
denotes |
BDNF |
| T5324 |
1445-1447 |
IN |
denotes |
of |
| T5323 |
1434-1444 |
NN |
denotes |
expression |
| T5322 |
1431-1433 |
IN |
denotes |
in |
| T5321 |
1414-1420 |
JJ |
denotes |
severe |
| T5320 |
1421-1430 |
NN |
denotes |
reduction |
| T5319 |
1412-1413 |
DT |
denotes |
a |
| T5318 |
1397-1401 |
FW |
denotes |
situ |
| T5317 |
1394-1396 |
FW |
denotes |
in |
| T5316 |
1402-1406 |
NNS |
denotes |
data |
| T5315 |
1390-1393 |
PRP$ |
denotes |
our |
| T5314 |
1388-1390 |
, |
denotes |
, |
| T5313 |
1378-1388 |
NN |
denotes |
suggestion |
| T5312 |
1373-1377 |
DT |
denotes |
this |
| T5311 |
1368-1372 |
IN |
denotes |
with |
| T5310 |
1358-1367 |
NN |
denotes |
agreement |
| T5309 |
1407-1411 |
VBP |
denotes |
show |
| T5308 |
1355-1357 |
IN |
denotes |
In |
| T5307 |
1354-1466 |
sentence |
denotes |
In agreement with this suggestion, our in situ data show a severe reduction in expression of BDNF (Figs. 8, 9). |
| T5306 |
1353-1354 |
. |
denotes |
. |
| T5305 |
1344-1348 |
JJ |
denotes |
null |
| T5304 |
1338-1343 |
NN |
denotes |
Brn3c |
| T5303 |
1328-1337 |
JJ |
denotes |
postnatal |
| T5302 |
1322-1327 |
JJ |
denotes |
early |
| T5301 |
1318-1321 |
CC |
denotes |
and |
| T5300 |
1349-1353 |
NNS |
denotes |
mice |
| T5299 |
1310-1317 |
JJ |
denotes |
newborn |
| T5298 |
1307-1309 |
IN |
denotes |
in |
| T5297 |
1291-1299 |
JJ |
denotes |
afferent |
| T5296 |
1300-1306 |
NNS |
denotes |
fibers |
| T5295 |
1285-1290 |
PRP$ |
denotes |
their |
| T5294 |
1281-1284 |
CC |
denotes |
and |
| T5293 |
1273-1280 |
NNS |
denotes |
neurons |
| T5292 |
1265-1272 |
JJ |
denotes |
primary |
| T5291 |
1262-1264 |
IN |
denotes |
of |
| T5290 |
1252-1261 |
NN |
denotes |
retention |
| T5289 |
1249-1251 |
IN |
denotes |
to |
| T5288 |
1227-1235 |
JJ |
denotes |
immature |
| T5287 |
1236-1242 |
NN |
denotes |
target |
| T5286 |
1223-1226 |
DT |
denotes |
the |
| T5285 |
1220-1222 |
IN |
denotes |
in |
| T5284 |
1206-1219 |
NNS |
denotes |
neurotrophins |
| T5283 |
1203-1205 |
IN |
denotes |
of |
| T5282 |
1192-1202 |
NN |
denotes |
expression |
| T5281 |
1184-1191 |
JJ |
denotes |
limited |
| T5280 |
1243-1248 |
VBZ |
denotes |
leads |
| T5279 |
1179-1183 |
IN |
denotes |
that |
| T5278 |
1171-1178 |
VBP |
denotes |
suggest |
| T5277 |
1168-1170 |
PRP |
denotes |
We |
| T5276 |
1167-1354 |
sentence |
denotes |
We suggest that limited expression of neurotrophins in the immature target leads to retention of primary neurons and their afferent fibers in newborn and early postnatal Brn3c null mice. |
| T5275 |
1166-1167 |
. |
denotes |
. |
| T5274 |
1157-1166 |
NN |
denotes |
periphery |
| T5273 |
1153-1156 |
DT |
denotes |
the |
| T5272 |
1150-1152 |
IN |
denotes |
on |
| T5271 |
1140-1149 |
RB |
denotes |
crucially |
| T5270 |
1116-1123 |
JJ |
denotes |
primary |
| T5269 |
1124-1131 |
NNS |
denotes |
neurons |
| T5268 |
1112-1115 |
JJ |
denotes |
ear |
| T5267 |
1109-1111 |
IN |
denotes |
of |
| T5266 |
1100-1108 |
NN |
denotes |
survival |
| T5265 |
1096-1099 |
DT |
denotes |
the |
| T5264 |
1132-1139 |
VBZ |
denotes |
depends |
| T5263 |
1091-1095 |
IN |
denotes |
that |
| T5262 |
1083-1090 |
VBG |
denotes |
arguing |
| T5261 |
1078-1082 |
RB |
denotes |
thus |
| T5477 |
2265-2269 |
NN |
denotes |
BDNF |
| T5260 |
1076-1077 |
-RRB- |
denotes |
] |
| T5259 |
1074-1076 |
CD |
denotes |
22 |
| T5258 |
1073-1074 |
-LRB- |
denotes |
[ |
| T5257 |
1069-1072 |
NN |
denotes |
CNS |
| T5256 |
1065-1068 |
DT |
denotes |
the |
| T5255 |
1062-1064 |
IN |
denotes |
in |
| T5254 |
1048-1061 |
NN |
denotes |
embryogenesis |
| T5253 |
1041-1047 |
IN |
denotes |
during |
| T5252 |
1024-1030 |
RB |
denotes |
barely |
| T5251 |
1021-1023 |
VBZ |
denotes |
is |
| T5250 |
1015-1020 |
NN |
denotes |
Brn3c |
| T5249 |
1013-1015 |
, |
denotes |
, |
| T5248 |
1005-1013 |
NN |
denotes |
contrast |
| T5247 |
1031-1040 |
VBN |
denotes |
expressed |
| T5246 |
1002-1004 |
IN |
denotes |
In |
| T5245 |
1001-1167 |
sentence |
denotes |
In contrast, Brn3c is barely expressed during embryogenesis in the CNS [22] thus arguing that the survival of ear primary neurons depends crucially on the periphery. |
| T5244 |
1000-1001 |
. |
denotes |
. |
| T5243 |
993-1000 |
NNS |
denotes |
embryos |
| T5242 |
988-992 |
JJ |
denotes |
late |
| T5241 |
985-987 |
IN |
denotes |
in |
| T5240 |
977-984 |
NNS |
denotes |
effects |
| T5239 |
971-976 |
PRP$ |
denotes |
their |
| T5238 |
963-970 |
VBP |
denotes |
achieve |
| T5237 |
959-962 |
CC |
denotes |
and |
| T5236 |
944-958 |
RB |
denotes |
simultaneously |
| T5235 |
938-943 |
NN |
denotes |
brain |
| T5234 |
934-937 |
DT |
denotes |
the |
| T5233 |
930-933 |
CC |
denotes |
and |
| T5232 |
912-922 |
JJ |
denotes |
peripheral |
| T5231 |
908-911 |
DT |
denotes |
the |
| T5230 |
923-929 |
NN |
denotes |
target |
| T5229 |
903-907 |
CC |
denotes |
both |
| T5228 |
900-902 |
IN |
denotes |
in |
| T5227 |
889-899 |
NN |
denotes |
expression |
| T5226 |
874-878 |
NN |
denotes |
date |
| T5225 |
871-873 |
IN |
denotes |
to |
| T5224 |
863-870 |
VBN |
denotes |
studied |
| T5223 |
850-854 |
JJ |
denotes |
null |
| T5222 |
841-849 |
NN |
denotes |
receptor |
| T5221 |
827-828 |
HYPH |
denotes |
/ |
| T5220 |
828-840 |
NN |
denotes |
neurotrophin |
| T5219 |
815-827 |
NN |
denotes |
neurotrophin |
| T5218 |
855-862 |
NNS |
denotes |
mutants |
| T5217 |
811-814 |
DT |
denotes |
the |
| T5216 |
808-810 |
IN |
denotes |
of |
| T5215 |
804-807 |
DT |
denotes |
all |
| T5214 |
802-804 |
, |
denotes |
, |
| T5213 |
879-888 |
VBP |
denotes |
eliminate |
| T5212 |
794-802 |
RB |
denotes |
Moreover |
| T5188 |
677-682 |
JJ |
denotes |
small |
| T5187 |
683-691 |
NN |
denotes |
decrease |
| T5186 |
675-676 |
DT |
denotes |
a |
| T5185 |
666-671 |
EX |
denotes |
there |
| T5184 |
644-657 |
JJ |
denotes |
heterozygotic |
| T5183 |
658-665 |
NNS |
denotes |
animals |
| T5182 |
639-643 |
NN |
denotes |
BDNF |
| T5181 |
636-638 |
IN |
denotes |
in |
| T5180 |
634-636 |
, |
denotes |
, |
| T5179 |
627-634 |
NN |
denotes |
example |
| T5178 |
672-674 |
VBZ |
denotes |
is |
| T5177 |
623-626 |
IN |
denotes |
For |
| T5176 |
622-793 |
sentence |
denotes |
For example, in BDNF heterozygotic animals there is a small decrease in the number of sensory neurons in the ear [13] but no change in the overall pattern of innervation. |
| T5175 |
621-622 |
. |
denotes |
. |
| T5174 |
617-621 |
FW |
denotes |
vivo |
| T5173 |
614-616 |
FW |
denotes |
in |
| T5172 |
607-613 |
NN |
denotes |
theory |
| T5171 |
602-606 |
DT |
denotes |
this |
| T5170 |
599-601 |
IN |
denotes |
of |
| T5169 |
582-587 |
JJ |
denotes |
basic |
| T5168 |
588-598 |
NN |
denotes |
assumption |
| T5167 |
578-581 |
DT |
denotes |
the |
| T5166 |
561-570 |
RB |
denotes |
partially |
| T5165 |
556-560 |
RB |
denotes |
only |
| T5164 |
554-556 |
, |
denotes |
, |
| T5163 |
546-554 |
RB |
denotes |
entirely |
| T5162 |
527-531 |
JJR |
denotes |
more |
| T5161 |
524-526 |
CC |
denotes |
or |
| T5160 |
532-545 |
NNS |
denotes |
neurotrophins |
| T5159 |
520-523 |
CD |
denotes |
one |
| T5158 |
509-519 |
VBD |
denotes |
eliminated |
| T5157 |
503-508 |
WDT |
denotes |
which |
| T5156 |
501-503 |
, |
denotes |
, |
| T5155 |
571-577 |
VBN |
denotes |
tested |
| T5154 |
490-501 |
NNS |
denotes |
experiments |
| T5153 |
485-489 |
NN |
denotes |
Past |
| T5152 |
484-622 |
sentence |
denotes |
Past experiments, which eliminated one or more neurotrophins entirely, only partially tested the basic assumption of this theory in vivo. |
| T5151 |
483-484 |
. |
denotes |
. |
| T5150 |
482-483 |
-RRB- |
denotes |
] |
| T5149 |
480-482 |
CD |
denotes |
21 |
| T5148 |
479-480 |
-LRB- |
denotes |
[ |
| T5147 |
465-478 |
NNS |
denotes |
neurotrophins |
| T5146 |
462-464 |
IN |
denotes |
of |
| T5145 |
446-454 |
JJ |
denotes |
critical |
| T5144 |
455-461 |
NN |
denotes |
amount |
| T5143 |
444-445 |
DT |
denotes |
a |
| T5142 |
439-443 |
IN |
denotes |
with |
| T5141 |
433-438 |
DT |
denotes |
these |
| T5140 |
428-432 |
RB |
denotes |
only |
| T5139 |
418-427 |
VBG |
denotes |
providing |
| T5138 |
415-417 |
IN |
denotes |
by |
| T5137 |
399-406 |
JJ |
denotes |
sensory |
| T5136 |
389-398 |
VBN |
denotes |
connected |
| T5135 |
380-388 |
RB |
denotes |
properly |
| T5134 |
407-414 |
NNS |
denotes |
neurons |
| T5133 |
375-379 |
RB |
denotes |
only |
| T5132 |
367-374 |
VB |
denotes |
support |
| T5131 |
364-366 |
TO |
denotes |
to |
| T5130 |
350-356 |
NN |
denotes |
target |
| T5129 |
357-363 |
NN |
denotes |
tissue |
| T5128 |
346-349 |
DT |
denotes |
the |
| T5127 |
343-345 |
IN |
denotes |
by |
| T5126 |
330-333 |
VBP |
denotes |
are |
| T5125 |
316-329 |
NNS |
denotes |
neurotrophins |
| T5124 |
313-315 |
IN |
denotes |
of |
| T5123 |
294-301 |
JJ |
denotes |
limited |
| T5122 |
302-312 |
NNS |
denotes |
quantities |
| T5121 |
289-293 |
RB |
denotes |
only |
| T5120 |
334-342 |
VBN |
denotes |
released |
| T5119 |
284-288 |
IN |
denotes |
that |
| T5118 |
268-275 |
NN |
denotes |
support |
| T5117 |
255-267 |
JJ |
denotes |
neurotrophic |
| T5116 |
251-254 |
IN |
denotes |
via |
| T5115 |
239-250 |
NNS |
denotes |
connections |
| T5114 |
230-238 |
JJ |
denotes |
neuronal |
| T5113 |
227-229 |
IN |
denotes |
of |
| T5112 |
216-226 |
NN |
denotes |
regulation |
| T5111 |
213-215 |
IN |
denotes |
of |
| T5110 |
206-212 |
NN |
denotes |
theory |
| T5109 |
201-205 |
DT |
denotes |
this |
| T5108 |
199-201 |
, |
denotes |
, |
| T5107 |
192-199 |
NN |
denotes |
essence |
| T5106 |
276-283 |
VBZ |
denotes |
implies |
| T5105 |
189-191 |
IN |
denotes |
In |
| T5104 |
188-484 |
sentence |
denotes |
In essence, this theory of regulation of neuronal connections via neurotrophic support implies that only limited quantities of neurotrophins are released by the target tissue to support only properly connected sensory neurons by providing only these with a critical amount of neurotrophins [21]. |
| T5103 |
187-188 |
. |
denotes |
. |
| T5102 |
177-181 |
NN |
denotes |
cell |
| T5101 |
182-187 |
NN |
denotes |
death |
| T5100 |
168-176 |
VBN |
denotes |
mediated |
| T5099 |
161-167 |
NN |
denotes |
target |
| T5098 |
157-160 |
IN |
denotes |
for |
| T5097 |
147-156 |
NNS |
denotes |
mediators |
| T5096 |
143-146 |
DT |
denotes |
the |
| T5095 |
140-142 |
IN |
denotes |
as |
| T5094 |
124-128 |
VBN |
denotes |
been |
| T5093 |
119-123 |
RB |
denotes |
long |
| T5092 |
114-118 |
VBP |
denotes |
have |
| T5091 |
129-139 |
VBN |
denotes |
implicated |
| T5090 |
100-113 |
NNS |
denotes |
neurotrophins |
| T5089 |
96-99 |
DT |
denotes |
The |
| T5088 |
95-188 |
sentence |
denotes |
The neurotrophins have long been implicated as the mediators for target mediated cell death. |
| T5087 |
93-95 |
NN |
denotes |
P8 |
| T5086 |
87-92 |
IN |
denotes |
until |
| T5085 |
76-86 |
NN |
denotes |
projection |
| T5084 |
67-75 |
JJ |
denotes |
afferent |
| T5083 |
46-59 |
NNS |
denotes |
neurotrophins |
| T5082 |
43-45 |
IN |
denotes |
of |
| T5081 |
32-42 |
NN |
denotes |
expression |
| T5080 |
24-31 |
JJ |
denotes |
limited |
| T5079 |
20-23 |
CC |
denotes |
and |
| T5078 |
60-66 |
VBP |
denotes |
rescue |
| T5077 |
9-13 |
NN |
denotes |
hair |
| T5076 |
14-19 |
NNS |
denotes |
cells |
| T5075 |
0-8 |
JJ |
denotes |
Immature |
| T5211 |
793-1001 |
sentence |
denotes |
Moreover, all of the neurotrophin/neurotrophin receptor null mutants studied to date eliminate expression in both the peripheral target and the brain simultaneously and achieve their effects in late embryos. |
| T5210 |
792-793 |
. |
denotes |
. |
| T5209 |
781-792 |
NN |
denotes |
innervation |
| T5208 |
778-780 |
IN |
denotes |
of |
| T5207 |
762-769 |
JJ |
denotes |
overall |
| T5206 |
770-777 |
NN |
denotes |
pattern |
| T5205 |
758-761 |
DT |
denotes |
the |
| T5204 |
755-757 |
IN |
denotes |
in |
| T5203 |
748-754 |
NN |
denotes |
change |
| T5202 |
745-747 |
DT |
denotes |
no |
| T5201 |
741-744 |
CC |
denotes |
but |
| T5200 |
739-740 |
-RRB- |
denotes |
] |
| T5199 |
737-739 |
CD |
denotes |
13 |
| T5198 |
736-737 |
-LRB- |
denotes |
[ |
| T5197 |
732-735 |
NN |
denotes |
ear |
| T5196 |
728-731 |
DT |
denotes |
the |
| T5195 |
725-727 |
IN |
denotes |
in |
| T5194 |
717-724 |
NNS |
denotes |
neurons |
| T5193 |
709-716 |
JJ |
denotes |
sensory |
| T5192 |
706-708 |
IN |
denotes |
of |
| T5191 |
699-705 |
NN |
denotes |
number |
| T5190 |
695-698 |
DT |
denotes |
the |
| T5189 |
692-694 |
IN |
denotes |
in |
| T5693 |
3243-3246 |
NN |
denotes |
day |
| R3095 |
T5075 |
T5076 |
amod |
Immature,cells |
| R3096 |
T5076 |
T5078 |
nsubj |
cells,rescue |
| R3097 |
T5077 |
T5076 |
compound |
hair,cells |
| R3098 |
T5079 |
T5076 |
cc |
and,cells |
| R3099 |
T5080 |
T5081 |
amod |
limited,expression |
| R3100 |
T5081 |
T5076 |
conj |
expression,cells |
| R3101 |
T5082 |
T5081 |
prep |
of,expression |
| R3102 |
T5083 |
T5082 |
pobj |
neurotrophins,of |
| R3103 |
T5084 |
T5085 |
amod |
afferent,projection |
| R3104 |
T5085 |
T5078 |
dobj |
projection,rescue |
| R3105 |
T5086 |
T5078 |
prep |
until,rescue |
| R3106 |
T5087 |
T5086 |
pobj |
P8,until |
| R3107 |
T5089 |
T5090 |
det |
The,neurotrophins |
| R3108 |
T5090 |
T5091 |
nsubjpass |
neurotrophins,implicated |
| R3109 |
T5092 |
T5091 |
aux |
have,implicated |
| R3110 |
T5093 |
T5091 |
advmod |
long,implicated |
| R3111 |
T5094 |
T5091 |
auxpass |
been,implicated |
| R3112 |
T5095 |
T5091 |
prep |
as,implicated |
| R3113 |
T5096 |
T5097 |
det |
the,mediators |
| R3114 |
T5097 |
T5095 |
pobj |
mediators,as |
| R3115 |
T5098 |
T5097 |
prep |
for,mediators |
| R3116 |
T5099 |
T5100 |
npadvmod |
target,mediated |
| R3117 |
T5100 |
T5101 |
amod |
mediated,death |
| R3118 |
T5101 |
T5098 |
pobj |
death,for |
| R3119 |
T5102 |
T5101 |
compound |
cell,death |
| R3120 |
T5103 |
T5091 |
punct |
.,implicated |
| R3121 |
T5105 |
T5106 |
prep |
In,implies |
| R3122 |
T5107 |
T5105 |
pobj |
essence,In |
| R3123 |
T5108 |
T5106 |
punct |
", ",implies |
| R3124 |
T5109 |
T5110 |
det |
this,theory |
| R3125 |
T5110 |
T5106 |
nsubj |
theory,implies |
| R3126 |
T5111 |
T5110 |
prep |
of,theory |
| R3127 |
T5112 |
T5111 |
pobj |
regulation,of |
| R3128 |
T5113 |
T5112 |
prep |
of,regulation |
| R3129 |
T5114 |
T5115 |
amod |
neuronal,connections |
| R3130 |
T5115 |
T5113 |
pobj |
connections,of |
| R3131 |
T5116 |
T5112 |
prep |
via,regulation |
| R3132 |
T5117 |
T5118 |
amod |
neurotrophic,support |
| R3133 |
T5118 |
T5116 |
pobj |
support,via |
| R3134 |
T5119 |
T5120 |
mark |
that,released |
| R3135 |
T5120 |
T5106 |
ccomp |
released,implies |
| R3136 |
T5121 |
T5122 |
advmod |
only,quantities |
| R3137 |
T5122 |
T5120 |
nsubjpass |
quantities,released |
| R3138 |
T5123 |
T5122 |
amod |
limited,quantities |
| R3139 |
T5124 |
T5122 |
prep |
of,quantities |
| R3140 |
T5125 |
T5124 |
pobj |
neurotrophins,of |
| R3141 |
T5126 |
T5120 |
auxpass |
are,released |
| R3142 |
T5127 |
T5120 |
agent |
by,released |
| R3143 |
T5128 |
T5129 |
det |
the,tissue |
| R3144 |
T5129 |
T5127 |
pobj |
tissue,by |
| R3145 |
T5130 |
T5129 |
compound |
target,tissue |
| R3146 |
T5131 |
T5132 |
aux |
to,support |
| R3147 |
T5132 |
T5120 |
advcl |
support,released |
| R3148 |
T5133 |
T5134 |
advmod |
only,neurons |
| R3149 |
T5134 |
T5132 |
dobj |
neurons,support |
| R3150 |
T5135 |
T5136 |
advmod |
properly,connected |
| R3151 |
T5136 |
T5134 |
amod |
connected,neurons |
| R3152 |
T5137 |
T5134 |
amod |
sensory,neurons |
| R3153 |
T5138 |
T5132 |
prep |
by,support |
| R3154 |
T5139 |
T5138 |
pcomp |
providing,by |
| R3155 |
T5140 |
T5141 |
advmod |
only,these |
| R3156 |
T5141 |
T5139 |
dobj |
these,providing |
| R3157 |
T5142 |
T5139 |
prep |
with,providing |
| R3158 |
T5143 |
T5144 |
det |
a,amount |
| R3159 |
T5144 |
T5142 |
pobj |
amount,with |
| R3160 |
T5145 |
T5144 |
amod |
critical,amount |
| R3161 |
T5146 |
T5144 |
prep |
of,amount |
| R3162 |
T5147 |
T5146 |
pobj |
neurotrophins,of |
| R3163 |
T5148 |
T5149 |
punct |
[,21 |
| R3164 |
T5149 |
T5106 |
parataxis |
21,implies |
| R3165 |
T5150 |
T5149 |
punct |
],21 |
| R3166 |
T5151 |
T5106 |
punct |
.,implies |
| R3167 |
T5153 |
T5154 |
compound |
Past,experiments |
| R3168 |
T5154 |
T5155 |
nsubj |
experiments,tested |
| R3169 |
T5156 |
T5154 |
punct |
", ",experiments |
| R3170 |
T5157 |
T5158 |
dep |
which,eliminated |
| R3171 |
T5158 |
T5154 |
relcl |
eliminated,experiments |
| R3172 |
T5159 |
T5160 |
nummod |
one,neurotrophins |
| R3173 |
T5160 |
T5158 |
dobj |
neurotrophins,eliminated |
| R3174 |
T5161 |
T5159 |
cc |
or,one |
| R3175 |
T5162 |
T5159 |
conj |
more,one |
| R3176 |
T5163 |
T5158 |
advmod |
entirely,eliminated |
| R3177 |
T5164 |
T5155 |
punct |
", ",tested |
| R3178 |
T5165 |
T5166 |
advmod |
only,partially |
| R3179 |
T5166 |
T5155 |
advmod |
partially,tested |
| R3180 |
T5167 |
T5168 |
det |
the,assumption |
| R3181 |
T5168 |
T5155 |
dobj |
assumption,tested |
| R3182 |
T5169 |
T5168 |
amod |
basic,assumption |
| R3183 |
T5170 |
T5168 |
prep |
of,assumption |
| R3184 |
T5171 |
T5172 |
det |
this,theory |
| R3185 |
T5172 |
T5170 |
pobj |
theory,of |
| R3186 |
T5173 |
T5174 |
advmod |
in,vivo |
| R3187 |
T5174 |
T5155 |
advmod |
vivo,tested |
| R3188 |
T5175 |
T5155 |
punct |
.,tested |
| R3189 |
T5177 |
T5178 |
prep |
For,is |
| R3190 |
T5179 |
T5177 |
pobj |
example,For |
| R3191 |
T5180 |
T5178 |
punct |
", ",is |
| R3192 |
T5181 |
T5178 |
prep |
in,is |
| R3193 |
T5182 |
T5183 |
nmod |
BDNF,animals |
| R3194 |
T5183 |
T5181 |
pobj |
animals,in |
| R3195 |
T5184 |
T5183 |
amod |
heterozygotic,animals |
| R3196 |
T5185 |
T5178 |
expl |
there,is |
| R3197 |
T5186 |
T5187 |
det |
a,decrease |
| R3198 |
T5187 |
T5178 |
attr |
decrease,is |
| R3199 |
T5188 |
T5187 |
amod |
small,decrease |
| R3200 |
T5189 |
T5187 |
prep |
in,decrease |
| R3201 |
T5190 |
T5191 |
det |
the,number |
| R3202 |
T5191 |
T5189 |
pobj |
number,in |
| R3203 |
T5192 |
T5191 |
prep |
of,number |
| R3204 |
T5193 |
T5194 |
amod |
sensory,neurons |
| R3205 |
T5194 |
T5192 |
pobj |
neurons,of |
| R3206 |
T5195 |
T5194 |
prep |
in,neurons |
| R3207 |
T5196 |
T5197 |
det |
the,ear |
| R3208 |
T5197 |
T5195 |
pobj |
ear,in |
| R3209 |
T5198 |
T5199 |
punct |
[,13 |
| R3210 |
T5199 |
T5187 |
parataxis |
13,decrease |
| R3211 |
T5200 |
T5199 |
punct |
],13 |
| R3212 |
T5201 |
T5187 |
cc |
but,decrease |
| R3213 |
T5202 |
T5203 |
det |
no,change |
| R3214 |
T5203 |
T5187 |
conj |
change,decrease |
| R3215 |
T5204 |
T5203 |
prep |
in,change |
| R3216 |
T5205 |
T5206 |
det |
the,pattern |
| R3217 |
T5206 |
T5204 |
pobj |
pattern,in |
| R3218 |
T5207 |
T5206 |
amod |
overall,pattern |
| R3219 |
T5208 |
T5206 |
prep |
of,pattern |
| R3220 |
T5209 |
T5208 |
pobj |
innervation,of |
| R3221 |
T5210 |
T5178 |
punct |
.,is |
| R3222 |
T5212 |
T5213 |
advmod |
Moreover,eliminate |
| R3223 |
T5214 |
T5213 |
punct |
", ",eliminate |
| R3224 |
T5215 |
T5213 |
nsubj |
all,eliminate |
| R3225 |
T5216 |
T5215 |
prep |
of,all |
| R3226 |
T5217 |
T5218 |
det |
the,mutants |
| R3227 |
T5218 |
T5216 |
pobj |
mutants,of |
| R3228 |
T5219 |
T5220 |
nmod |
neurotrophin,neurotrophin |
| R3229 |
T5220 |
T5222 |
nmod |
neurotrophin,receptor |
| R3230 |
T5221 |
T5220 |
punct |
/,neurotrophin |
| R3231 |
T5222 |
T5218 |
nmod |
receptor,mutants |
| R3232 |
T5223 |
T5218 |
amod |
null,mutants |
| R3233 |
T5224 |
T5218 |
acl |
studied,mutants |
| R3234 |
T5225 |
T5224 |
prep |
to,studied |
| R3235 |
T5226 |
T5225 |
pobj |
date,to |
| R3236 |
T5227 |
T5213 |
dobj |
expression,eliminate |
| R3237 |
T5228 |
T5213 |
prep |
in,eliminate |
| R3238 |
T5229 |
T5230 |
preconj |
both,target |
| R3239 |
T5230 |
T5228 |
pobj |
target,in |
| R3240 |
T5231 |
T5230 |
det |
the,target |
| R3241 |
T5232 |
T5230 |
amod |
peripheral,target |
| R3242 |
T5233 |
T5230 |
cc |
and,target |
| R3243 |
T5234 |
T5235 |
det |
the,brain |
| R3244 |
T5235 |
T5230 |
conj |
brain,target |
| R3245 |
T5236 |
T5213 |
advmod |
simultaneously,eliminate |
| R3246 |
T5237 |
T5213 |
cc |
and,eliminate |
| R3247 |
T5238 |
T5213 |
conj |
achieve,eliminate |
| R3248 |
T5239 |
T5240 |
poss |
their,effects |
| R3249 |
T5240 |
T5238 |
dobj |
effects,achieve |
| R3250 |
T5241 |
T5238 |
prep |
in,achieve |
| R3251 |
T5242 |
T5243 |
amod |
late,embryos |
| R3252 |
T5243 |
T5241 |
pobj |
embryos,in |
| R3253 |
T5244 |
T5213 |
punct |
.,eliminate |
| R3254 |
T5246 |
T5247 |
prep |
In,expressed |
| R3255 |
T5248 |
T5246 |
pobj |
contrast,In |
| R3256 |
T5249 |
T5247 |
punct |
", ",expressed |
| R3257 |
T5250 |
T5247 |
nsubjpass |
Brn3c,expressed |
| R3258 |
T5251 |
T5247 |
auxpass |
is,expressed |
| R3259 |
T5252 |
T5247 |
advmod |
barely,expressed |
| R3260 |
T5253 |
T5247 |
prep |
during,expressed |
| R3261 |
T5254 |
T5253 |
pobj |
embryogenesis,during |
| R3262 |
T5255 |
T5247 |
prep |
in,expressed |
| R3263 |
T5256 |
T5257 |
det |
the,CNS |
| R3264 |
T5257 |
T5255 |
pobj |
CNS,in |
| R3265 |
T5258 |
T5259 |
punct |
[,22 |
| R3266 |
T5259 |
T5247 |
parataxis |
22,expressed |
| R3267 |
T5260 |
T5259 |
punct |
],22 |
| R3268 |
T5261 |
T5262 |
advmod |
thus,arguing |
| R3269 |
T5262 |
T5247 |
advcl |
arguing,expressed |
| R3270 |
T5263 |
T5264 |
mark |
that,depends |
| R3271 |
T5264 |
T5262 |
ccomp |
depends,arguing |
| R3272 |
T5265 |
T5266 |
det |
the,survival |
| R3273 |
T5266 |
T5264 |
nsubj |
survival,depends |
| R3274 |
T5267 |
T5266 |
prep |
of,survival |
| R3275 |
T5268 |
T5269 |
amod |
ear,neurons |
| R3276 |
T5269 |
T5267 |
pobj |
neurons,of |
| R3277 |
T5270 |
T5269 |
amod |
primary,neurons |
| R3278 |
T5271 |
T5264 |
advmod |
crucially,depends |
| R3279 |
T5272 |
T5264 |
prep |
on,depends |
| R3280 |
T5273 |
T5274 |
det |
the,periphery |
| R3281 |
T5274 |
T5272 |
pobj |
periphery,on |
| R3282 |
T5275 |
T5247 |
punct |
.,expressed |
| R3283 |
T5277 |
T5278 |
nsubj |
We,suggest |
| R3284 |
T5279 |
T5280 |
mark |
that,leads |
| R3285 |
T5280 |
T5278 |
ccomp |
leads,suggest |
| R3286 |
T5281 |
T5282 |
amod |
limited,expression |
| R3287 |
T5282 |
T5280 |
nsubj |
expression,leads |
| R3288 |
T5283 |
T5282 |
prep |
of,expression |
| R3289 |
T5284 |
T5283 |
pobj |
neurotrophins,of |
| R3290 |
T5285 |
T5282 |
prep |
in,expression |
| R3291 |
T5286 |
T5287 |
det |
the,target |
| R3292 |
T5287 |
T5285 |
pobj |
target,in |
| R3293 |
T5288 |
T5287 |
amod |
immature,target |
| R3294 |
T5289 |
T5280 |
prep |
to,leads |
| R3295 |
T5290 |
T5289 |
pobj |
retention,to |
| R3296 |
T5291 |
T5290 |
prep |
of,retention |
| R3297 |
T5292 |
T5293 |
amod |
primary,neurons |
| R3298 |
T5293 |
T5291 |
pobj |
neurons,of |
| R3299 |
T5294 |
T5293 |
cc |
and,neurons |
| R3300 |
T5295 |
T5296 |
poss |
their,fibers |
| R3301 |
T5296 |
T5293 |
conj |
fibers,neurons |
| R3302 |
T5297 |
T5296 |
amod |
afferent,fibers |
| R3303 |
T5298 |
T5290 |
prep |
in,retention |
| R3304 |
T5299 |
T5300 |
amod |
newborn,mice |
| R3305 |
T5300 |
T5298 |
pobj |
mice,in |
| R3306 |
T5301 |
T5299 |
cc |
and,newborn |
| R3307 |
T5302 |
T5303 |
amod |
early,postnatal |
| R3308 |
T5303 |
T5299 |
conj |
postnatal,newborn |
| R3309 |
T5304 |
T5300 |
nmod |
Brn3c,mice |
| R3310 |
T5305 |
T5300 |
amod |
null,mice |
| R3311 |
T5306 |
T5278 |
punct |
.,suggest |
| R3312 |
T5308 |
T5309 |
prep |
In,show |
| R3313 |
T5310 |
T5308 |
pobj |
agreement,In |
| R3314 |
T5311 |
T5310 |
prep |
with,agreement |
| R3315 |
T5312 |
T5313 |
det |
this,suggestion |
| R3316 |
T5313 |
T5311 |
pobj |
suggestion,with |
| R3317 |
T5314 |
T5309 |
punct |
", ",show |
| R3318 |
T5315 |
T5316 |
poss |
our,data |
| R3319 |
T5316 |
T5309 |
nsubj |
data,show |
| R3320 |
T5317 |
T5318 |
advmod |
in,situ |
| R3321 |
T5318 |
T5316 |
amod |
situ,data |
| R3322 |
T5319 |
T5320 |
det |
a,reduction |
| R3323 |
T5320 |
T5309 |
dobj |
reduction,show |
| R3324 |
T5321 |
T5320 |
amod |
severe,reduction |
| R3325 |
T5322 |
T5320 |
prep |
in,reduction |
| R3326 |
T5323 |
T5322 |
pobj |
expression,in |
| R3327 |
T5324 |
T5323 |
prep |
of,expression |
| R3328 |
T5325 |
T5324 |
pobj |
BDNF,of |
| R3329 |
T5326 |
T5327 |
punct |
(,9 |
| R3330 |
T5327 |
T5309 |
parataxis |
9,show |
| R3331 |
T5328 |
T5327 |
nmod |
Figs.,9 |
| R3332 |
T5329 |
T5327 |
nummod |
8,9 |
| R3333 |
T5330 |
T5327 |
punct |
", ",9 |
| R3334 |
T5331 |
T5327 |
punct |
),9 |
| R3335 |
T5332 |
T5309 |
punct |
.,show |
| R3336 |
T5334 |
T5335 |
prep |
Despite,expressed |
| R3337 |
T5336 |
T5337 |
det |
this,reduction |
| R3338 |
T5337 |
T5334 |
pobj |
reduction,Despite |
| R3339 |
T5338 |
T5335 |
punct |
", ",expressed |
| R3340 |
T5339 |
T5340 |
det |
some,levels |
| R3341 |
T5340 |
T5335 |
nsubjpass |
levels,expressed |
| R3342 |
T5341 |
T5340 |
punct |
", ",levels |
| R3343 |
T5342 |
T5343 |
advmod |
apparently,significant |
| R3344 |
T5343 |
T5340 |
amod |
significant,levels |
| R3345 |
T5344 |
T5343 |
advmod |
biologically,significant |
| R3346 |
T5345 |
T5340 |
amod |
low,levels |
| R3347 |
T5346 |
T5340 |
prep |
of,levels |
| R3348 |
T5347 |
T5346 |
pobj |
neurotrophins,of |
| R3349 |
T5348 |
T5335 |
auxpass |
are,expressed |
| R3350 |
T5349 |
T5335 |
advmod |
apparently,expressed |
| R3351 |
T5350 |
T5335 |
prep |
in,expressed |
| R3352 |
T5351 |
T5352 |
det |
all,epithelia |
| R3353 |
T5352 |
T5350 |
pobj |
epithelia,in |
| R3354 |
T5353 |
T5352 |
amod |
sensory,epithelia |
| R3355 |
T5354 |
T5335 |
prep |
in,expressed |
| R3356 |
T5355 |
T5356 |
amod |
embryonic,mutants |
| R3357 |
T5356 |
T5354 |
pobj |
mutants,in |
| R3358 |
T5357 |
T5356 |
nmod |
Brn3c,mutants |
| R3359 |
T5358 |
T5356 |
amod |
null,mutants |
| R3360 |
T5359 |
T5335 |
punct |
.,expressed |
| R3361 |
T5361 |
T5362 |
nsubj |
It,appears |
| R3362 |
T5363 |
T5364 |
mark |
that,sustain |
| R3363 |
T5364 |
T5362 |
ccomp |
sustain,appears |
| R3364 |
T5365 |
T5366 |
advmod |
even,levels |
| R3365 |
T5366 |
T5364 |
nsubj |
levels,sustain |
| R3366 |
T5367 |
T5366 |
det |
these,levels |
| R3367 |
T5368 |
T5366 |
amod |
low,levels |
| R3368 |
T5369 |
T5366 |
prep |
of,levels |
| R3369 |
T5370 |
T5369 |
pobj |
neurotrophins,of |
| R3370 |
T5371 |
T5366 |
prep |
in,levels |
| R3371 |
T5372 |
T5373 |
det |
the,epithelia |
| R3372 |
T5373 |
T5371 |
pobj |
epithelia,in |
| R3373 |
T5374 |
T5373 |
amod |
vestibular,epithelia |
| R3374 |
T5375 |
T5373 |
amod |
sensory,epithelia |
| R3375 |
T5376 |
T5364 |
aux |
can,sustain |
| R3376 |
T5377 |
T5378 |
amod |
normal,outgrowth |
| R3377 |
T5378 |
T5364 |
dobj |
outgrowth,sustain |
| R3378 |
T5379 |
T5378 |
compound |
fiber,outgrowth |
| R3379 |
T5380 |
T5378 |
cc |
and,outgrowth |
| R3380 |
T5381 |
T5382 |
det |
a,maintenance |
| R3381 |
T5382 |
T5378 |
conj |
maintenance,outgrowth |
| R3382 |
T5383 |
T5382 |
amod |
limited,maintenance |
| R3383 |
T5384 |
T5364 |
prep |
until,sustain |
| R3384 |
T5385 |
T5384 |
pobj |
P0,until |
| R3385 |
T5386 |
T5362 |
punct |
.,appears |
| R3386 |
T5388 |
T5389 |
det |
The,level |
| R3387 |
T5389 |
T5392 |
nsubj |
level,is |
| R3388 |
T5390 |
T5391 |
advmod |
comparatively,high |
| R3389 |
T5391 |
T5389 |
amod |
high,level |
| R3390 |
T5393 |
T5389 |
prep |
of,level |
| R3391 |
T5394 |
T5395 |
nmod |
NT,expression |
| R3392 |
T5395 |
T5393 |
pobj |
expression,of |
| R3393 |
T5396 |
T5394 |
punct |
-,NT |
| R3394 |
T5397 |
T5394 |
nummod |
3,NT |
| R3395 |
T5398 |
T5389 |
prep |
in,level |
| R3396 |
T5399 |
T5400 |
nmod |
Brn3c,cochlea |
| R3397 |
T5400 |
T5398 |
pobj |
cochlea,in |
| R3398 |
T5401 |
T5400 |
amod |
null,cochlea |
| R3399 |
T5402 |
T5400 |
amod |
mutant,cochlea |
| R3400 |
T5403 |
T5389 |
punct |
", ",level |
| R3401 |
T5404 |
T5405 |
dep |
which,shown |
| R3402 |
T5405 |
T5389 |
relcl |
shown,level |
| R3403 |
T5406 |
T5405 |
aux |
has,shown |
| R3404 |
T5407 |
T5405 |
auxpass |
been,shown |
| R3405 |
T5408 |
T5409 |
aux |
to,be |
| R3406 |
T5409 |
T5405 |
xcomp |
be,shown |
| R3407 |
T5410 |
T5411 |
det |
the,neurotrophin |
| R3408 |
T5411 |
T5409 |
attr |
neurotrophin,be |
| R3409 |
T5412 |
T5413 |
advmod |
most,prominently |
| R3410 |
T5413 |
T5414 |
advmod |
prominently,supporting |
| R3411 |
T5414 |
T5411 |
acl |
supporting,neurotrophin |
| R3412 |
T5415 |
T5416 |
amod |
spiral,neurons |
| R3413 |
T5416 |
T5414 |
dobj |
neurons,supporting |
| R3414 |
T5417 |
T5416 |
amod |
sensory,neurons |
| R3415 |
T5418 |
T5419 |
punct |
[,14 |
| R3416 |
T5419 |
T5405 |
parataxis |
14,shown |
| R3417 |
T5420 |
T5419 |
nummod |
6,14 |
| R3418 |
T5421 |
T5419 |
punct |
",",14 |
| R3419 |
T5422 |
T5419 |
nummod |
9,14 |
| R3420 |
T5423 |
T5419 |
punct |
",",14 |
| R3421 |
T5424 |
T5419 |
punct |
],14 |
| R3422 |
T5425 |
T5392 |
punct |
", ",is |
| R3423 |
T5426 |
T5392 |
prep |
in,is |
| R3424 |
T5427 |
T5426 |
pobj |
agreement,in |
| R3425 |
T5428 |
T5427 |
prep |
with,agreement |
| R3426 |
T5429 |
T5430 |
det |
the,development |
| R3427 |
T5430 |
T5428 |
pobj |
development,with |
| R3428 |
T5431 |
T5430 |
amod |
normal,development |
| R3429 |
T5432 |
T5430 |
prep |
of,development |
| R3430 |
T5433 |
T5434 |
amod |
cochlear,innervation |
| R3431 |
T5434 |
T5432 |
pobj |
innervation,of |
| R3432 |
T5435 |
T5430 |
prep |
in,development |
| R3433 |
T5436 |
T5437 |
amod |
newborn,mutants |
| R3434 |
T5437 |
T5435 |
pobj |
mutants,in |
| R3435 |
T5438 |
T5437 |
nmod |
Brn3c,mutants |
| R3436 |
T5439 |
T5437 |
amod |
null,mutants |
| R3437 |
T5440 |
T5392 |
punct |
.,is |
| R3438 |
T5442 |
T5443 |
mark |
Since,appears |
| R3439 |
T5443 |
T5445 |
advcl |
appears,appears |
| R3440 |
T5444 |
T5443 |
nsubj |
BDNF,appears |
| R3441 |
T5446 |
T5447 |
aux |
to,produced |
| R3442 |
T5447 |
T5443 |
xcomp |
produced,appears |
| R3443 |
T5448 |
T5447 |
auxpass |
be,produced |
| R3444 |
T5449 |
T5447 |
advmod |
exclusively,produced |
| R3445 |
T5450 |
T5447 |
agent |
by,produced |
| R3446 |
T5451 |
T5452 |
compound |
hair,cells |
| R3447 |
T5452 |
T5450 |
pobj |
cells,by |
| R3448 |
T5453 |
T5454 |
punct |
[,20 |
| R3449 |
T5454 |
T5443 |
parataxis |
20,appears |
| R3450 |
T5455 |
T5454 |
nummod |
6,20 |
| R3451 |
T5456 |
T5454 |
punct |
",",20 |
| R3452 |
T5457 |
T5454 |
nummod |
7,20 |
| R3453 |
T5458 |
T5454 |
punct |
",",20 |
| R3454 |
T5459 |
T5454 |
punct |
],20 |
| R3455 |
T5460 |
T5445 |
punct |
", ",appears |
| R3456 |
T5461 |
T5462 |
det |
the,lack |
| R3457 |
T5462 |
T5445 |
nsubj |
lack,appears |
| R3458 |
T5463 |
T5462 |
prep |
of,lack |
| R3459 |
T5464 |
T5465 |
amod |
terminal,differentiation |
| R3460 |
T5465 |
T5463 |
pobj |
differentiation,of |
| R3461 |
T5466 |
T5465 |
prep |
of,differentiation |
| R3462 |
T5467 |
T5468 |
compound |
hair,cells |
| R3463 |
T5468 |
T5466 |
pobj |
cells,of |
| R3464 |
T5469 |
T5470 |
aux |
to,accompanied |
| R3465 |
T5470 |
T5445 |
xcomp |
accompanied,appears |
| R3466 |
T5471 |
T5470 |
auxpass |
be,accompanied |
| R3467 |
T5472 |
T5470 |
agent |
by,accompanied |
| R3468 |
T5473 |
T5474 |
advmod |
only,expression |
| R3469 |
T5474 |
T5472 |
pobj |
expression,by |
| R3470 |
T5475 |
T5474 |
amod |
limited,expression |
| R3471 |
T5476 |
T5474 |
prep |
of,expression |
| R3472 |
T5477 |
T5476 |
pobj |
BDNF,of |
| R3473 |
T5478 |
T5470 |
punct |
", ",accompanied |
| R3474 |
T5479 |
T5480 |
mark |
as,is |
| R3475 |
T5480 |
T5470 |
advcl |
is,accompanied |
| R3476 |
T5481 |
T5482 |
det |
the,case |
| R3477 |
T5482 |
T5480 |
attr |
case,is |
| R3478 |
T5483 |
T5480 |
prep |
in,is |
| R3479 |
T5484 |
T5485 |
det |
the,cristae |
| R3480 |
T5485 |
T5483 |
pobj |
cristae,in |
| R3481 |
T5486 |
T5485 |
compound |
canal,cristae |
| R3482 |
T5487 |
T5488 |
punct |
(,Fig. |
| R3483 |
T5488 |
T5470 |
parataxis |
Fig.,accompanied |
| R3484 |
T5489 |
T5488 |
nummod |
8,Fig. |
| R3485 |
T5490 |
T5488 |
punct |
),Fig. |
| R3486 |
T5491 |
T5445 |
punct |
.,appears |
| R3487 |
T5493 |
T5494 |
compound |
Past,research |
| R3488 |
T5494 |
T5495 |
nsubj |
research,shown |
| R3489 |
T5496 |
T5495 |
aux |
has,shown |
| R3490 |
T5497 |
T5498 |
mark |
that,lost |
| R3491 |
T5498 |
T5495 |
ccomp |
lost,shown |
| R3492 |
T5499 |
T5498 |
prep |
in,lost |
| R3493 |
T5500 |
T5501 |
nmod |
BDNF,mutants |
| R3494 |
T5501 |
T5499 |
pobj |
mutants,in |
| R3495 |
T5502 |
T5500 |
cc |
and,BDNF |
| R3496 |
T5503 |
T5500 |
conj |
trkB,BDNF |
| R3497 |
T5504 |
T5501 |
amod |
null,mutants |
| R3498 |
T5505 |
T5506 |
det |
this,innervation |
| R3499 |
T5506 |
T5498 |
nsubjpass |
innervation,lost |
| R3500 |
T5507 |
T5506 |
prep |
to,innervation |
| R3501 |
T5508 |
T5509 |
amod |
canal,cristae |
| R3502 |
T5509 |
T5507 |
pobj |
cristae,to |
| R3503 |
T5510 |
T5498 |
auxpass |
is,lost |
| R3504 |
T5511 |
T5498 |
prep |
before,lost |
| R3505 |
T5512 |
T5511 |
pobj |
birth,before |
| R3506 |
T5513 |
T5514 |
punct |
[,13 |
| R3507 |
T5514 |
T5495 |
parataxis |
13,shown |
| R3508 |
T5515 |
T5514 |
nummod |
6,13 |
| R3509 |
T5516 |
T5514 |
punct |
",",13 |
| R3510 |
T5517 |
T5514 |
punct |
],13 |
| R3511 |
T5518 |
T5495 |
punct |
.,shown |
| R3512 |
T5520 |
T5521 |
mark |
That,are |
| R3513 |
T5521 |
T5528 |
csubj |
are,is |
| R3514 |
T5522 |
T5523 |
advmod |
even,levels |
| R3515 |
T5523 |
T5521 |
nsubj |
levels,are |
| R3516 |
T5524 |
T5523 |
det |
these,levels |
| R3517 |
T5525 |
T5523 |
amod |
low,levels |
| R3518 |
T5526 |
T5523 |
prep |
of,levels |
| R3519 |
T5527 |
T5526 |
pobj |
expression,of |
| R3520 |
T5529 |
T5521 |
acomp |
significant,are |
| R3521 |
T5530 |
T5528 |
acomp |
clear,is |
| R3522 |
T5531 |
T5528 |
prep |
from,is |
| R3523 |
T5532 |
T5533 |
det |
the,fact |
| R3524 |
T5533 |
T5531 |
pobj |
fact,from |
| R3525 |
T5534 |
T5535 |
mark |
that,receive |
| R3526 |
T5535 |
T5533 |
acl |
receive,fact |
| R3527 |
T5536 |
T5537 |
det |
all,epithelia |
| R3528 |
T5537 |
T5535 |
nsubj |
epithelia,receive |
| R3529 |
T5538 |
T5537 |
amod |
canal,epithelia |
| R3530 |
T5539 |
T5537 |
amod |
sensory,epithelia |
| R3531 |
T5540 |
T5541 |
det |
an,innervation |
| R3532 |
T5541 |
T5535 |
dobj |
innervation,receive |
| R3533 |
T5542 |
T5535 |
prep |
by,receive |
| R3534 |
T5543 |
T5544 |
preconj |
both,afferents |
| R3535 |
T5544 |
T5542 |
pobj |
afferents,by |
| R3536 |
T5545 |
T5544 |
cc |
and,afferents |
| R3537 |
T5546 |
T5544 |
conj |
efferents,afferents |
| R3538 |
T5547 |
T5535 |
prep |
at,receive |
| R3539 |
T5548 |
T5547 |
pobj |
birth,at |
| R3540 |
T5549 |
T5547 |
cc |
and,at |
| R3541 |
T5550 |
T5547 |
conj |
later,at |
| R3542 |
T5551 |
T5552 |
punct |
(,3 |
| R3543 |
T5552 |
T5528 |
parataxis |
3,is |
| R3544 |
T5553 |
T5552 |
nmod |
Figs.,3 |
| R3545 |
T5554 |
T5552 |
nummod |
2,3 |
| R3546 |
T5555 |
T5552 |
punct |
", ",3 |
| R3547 |
T5556 |
T5552 |
punct |
),3 |
| R3548 |
T5557 |
T5528 |
punct |
.,is |
| R3549 |
T5559 |
T5560 |
det |
The,situation |
| R3550 |
T5560 |
T5561 |
nsubj |
situation,is |
| R3551 |
T5562 |
T5560 |
prep |
in,situation |
| R3552 |
T5563 |
T5564 |
det |
the,utricle |
| R3553 |
T5564 |
T5562 |
pobj |
utricle,in |
| R3554 |
T5565 |
T5564 |
punct |
", ",utricle |
| R3555 |
T5566 |
T5564 |
conj |
saccule,utricle |
| R3556 |
T5567 |
T5566 |
cc |
and,saccule |
| R3557 |
T5568 |
T5566 |
conj |
cochlea,saccule |
| R3558 |
T5569 |
T5570 |
advmod |
less,clear |
| R3559 |
T5570 |
T5561 |
acomp |
clear,is |
| R3560 |
T5571 |
T5572 |
mark |
as,expressed |
| R3561 |
T5572 |
T5561 |
advcl |
expressed,is |
| R3562 |
T5573 |
T5574 |
preconj |
both,BDNF |
| R3563 |
T5574 |
T5572 |
nsubjpass |
BDNF,expressed |
| R3564 |
T5575 |
T5574 |
cc |
and,BDNF |
| R3565 |
T5576 |
T5574 |
conj |
NT,BDNF |
| R3566 |
T5577 |
T5576 |
punct |
-,NT |
| R3567 |
T5578 |
T5576 |
nummod |
3,NT |
| R3568 |
T5579 |
T5572 |
auxpass |
are,expressed |
| R3569 |
T5580 |
T5581 |
punct |
[,7 |
| R3570 |
T5581 |
T5561 |
parataxis |
7,is |
| R3571 |
T5582 |
T5581 |
nummod |
6,7 |
| R3572 |
T5583 |
T5581 |
punct |
",",7 |
| R3573 |
T5584 |
T5581 |
punct |
],7 |
| R3574 |
T5585 |
T5561 |
punct |
.,is |
| R3575 |
T5587 |
T5588 |
prep |
In,appears |
| R3576 |
T5589 |
T5587 |
pobj |
fact,In |
| R3577 |
T5590 |
T5588 |
punct |
", ",appears |
| R3578 |
T5591 |
T5588 |
nsubj |
it,appears |
| R3579 |
T5592 |
T5593 |
mark |
that,differ |
| R3580 |
T5593 |
T5588 |
ccomp |
differ,appears |
| R3581 |
T5594 |
T5595 |
det |
the,levels |
| R3582 |
T5595 |
T5593 |
nsubj |
levels,differ |
| R3583 |
T5596 |
T5595 |
prep |
of,levels |
| R3584 |
T5597 |
T5598 |
nmod |
NT,expression |
| R3585 |
T5598 |
T5596 |
pobj |
expression,of |
| R3586 |
T5599 |
T5597 |
punct |
-,NT |
| R3587 |
T5600 |
T5597 |
nummod |
3,NT |
| R3588 |
T5601 |
T5593 |
advmod |
hardly,differ |
| R3589 |
T5602 |
T5593 |
prep |
from,differ |
| R3590 |
T5603 |
T5602 |
pobj |
those,from |
| R3591 |
T5604 |
T5603 |
prep |
in,those |
| R3592 |
T5605 |
T5606 |
compound |
control,littermates |
| R3593 |
T5606 |
T5604 |
pobj |
littermates,in |
| R3594 |
T5607 |
T5608 |
punct |
(,9 |
| R3595 |
T5608 |
T5588 |
parataxis |
9,appears |
| R3596 |
T5609 |
T5608 |
nmod |
Figs.,9 |
| R3597 |
T5610 |
T5608 |
nummod |
8,9 |
| R3598 |
T5611 |
T5608 |
punct |
", ",9 |
| R3599 |
T5612 |
T5608 |
punct |
),9 |
| R3600 |
T5613 |
T5588 |
punct |
.,appears |
| R3601 |
T5615 |
T5616 |
det |
The,latter |
| R3602 |
T5616 |
T5617 |
nsubj |
latter,is |
| R3603 |
T5618 |
T5619 |
advmod |
particularly,obvious |
| R3604 |
T5619 |
T5617 |
acomp |
obvious,is |
| R3605 |
T5620 |
T5617 |
prep |
in,is |
| R3606 |
T5621 |
T5622 |
det |
the,apex |
| R3607 |
T5622 |
T5620 |
pobj |
apex,in |
| R3608 |
T5623 |
T5622 |
prep |
of,apex |
| R3609 |
T5624 |
T5625 |
det |
the,cochlea |
| R3610 |
T5625 |
T5623 |
pobj |
cochlea,of |
| R3611 |
T5626 |
T5617 |
punct |
.,is |
| R3612 |
T5628 |
T5629 |
prep |
In,expressed |
| R3613 |
T5630 |
T5628 |
pobj |
fact,In |
| R3614 |
T5631 |
T5629 |
punct |
", ",expressed |
| R3615 |
T5632 |
T5629 |
prep |
in,expressed |
| R3616 |
T5633 |
T5634 |
det |
the,cochlea |
| R3617 |
T5634 |
T5632 |
pobj |
cochlea,in |
| R3618 |
T5635 |
T5634 |
prep |
of,cochlea |
| R3619 |
T5636 |
T5635 |
pobj |
embryos,of |
| R3620 |
T5637 |
T5636 |
cc |
and,embryos |
| R3621 |
T5638 |
T5636 |
conj |
neonates,embryos |
| R3622 |
T5639 |
T5640 |
advmod |
as,as |
| R3623 |
T5640 |
T5632 |
cc |
as,in |
| R3624 |
T5641 |
T5640 |
advmod |
well,as |
| R3625 |
T5642 |
T5632 |
conj |
in,in |
| R3626 |
T5643 |
T5644 |
det |
the,saccule |
| R3627 |
T5644 |
T5642 |
pobj |
saccule,in |
| R3628 |
T5645 |
T5644 |
cc |
and,saccule |
| R3629 |
T5646 |
T5644 |
conj |
utricle,saccule |
| R3630 |
T5647 |
T5644 |
prep |
of,saccule |
| R3631 |
T5648 |
T5647 |
pobj |
embryos,of |
| R3632 |
T5649 |
T5629 |
punct |
", ",expressed |
| R3633 |
T5650 |
T5629 |
nsubjpass |
NT,expressed |
| R3634 |
T5651 |
T5650 |
punct |
-,NT |
| R3635 |
T5652 |
T5650 |
nummod |
3,NT |
| R3636 |
T5653 |
T5629 |
auxpass |
is,expressed |
| R3637 |
T5654 |
T5629 |
advmod |
predominantly,expressed |
| R3638 |
T5655 |
T5629 |
prep |
in,expressed |
| R3639 |
T5656 |
T5657 |
amod |
supporting,cells |
| R3640 |
T5657 |
T5655 |
pobj |
cells,in |
| R3641 |
T5658 |
T5659 |
punct |
[,6 |
| R3642 |
T5659 |
T5629 |
parataxis |
6,expressed |
| R3643 |
T5660 |
T5659 |
punct |
],6 |
| R3644 |
T5661 |
T5629 |
punct |
.,expressed |
| R3645 |
T5663 |
T5664 |
det |
This,expression |
| R3646 |
T5664 |
T5665 |
nsubj |
expression,preserve |
| R3647 |
T5666 |
T5664 |
prep |
of,expression |
| R3648 |
T5667 |
T5666 |
pobj |
NT,of |
| R3649 |
T5668 |
T5667 |
punct |
-,NT |
| R3650 |
T5669 |
T5667 |
nummod |
3,NT |
| R3651 |
T5670 |
T5664 |
prep |
in,expression |
| R3652 |
T5671 |
T5672 |
amod |
supporting,cells |
| R3653 |
T5672 |
T5670 |
pobj |
cells,in |
| R3654 |
T5673 |
T5664 |
prep |
in,expression |
| R3655 |
T5674 |
T5673 |
pobj |
embryos,in |
| R3656 |
T5675 |
T5674 |
cc |
and,embryos |
| R3657 |
T5676 |
T5674 |
conj |
neonates,embryos |
| R3658 |
T5677 |
T5665 |
aux |
may,preserve |
| R3659 |
T5678 |
T5665 |
advmod |
even,preserve |
| R3660 |
T5679 |
T5665 |
prep |
in,preserve |
| R3661 |
T5680 |
T5681 |
nmod |
Brn3c,mutants |
| R3662 |
T5681 |
T5679 |
pobj |
mutants,in |
| R3663 |
T5682 |
T5681 |
amod |
null,mutants |
| R3664 |
T5683 |
T5684 |
det |
the,neurons |
| R3665 |
T5684 |
T5665 |
dobj |
neurons,preserve |
| R3666 |
T5685 |
T5684 |
amod |
numerous,neurons |
| R3667 |
T5686 |
T5684 |
amod |
spiral,neurons |
| R3668 |
T5687 |
T5684 |
amod |
sensory,neurons |
| R3669 |
T5688 |
T5684 |
prep |
in,neurons |
| R3670 |
T5689 |
T5690 |
det |
the,apex |
| R3671 |
T5690 |
T5688 |
pobj |
apex,in |
| R3672 |
T5691 |
T5690 |
prep |
of,apex |
| R3673 |
T5692 |
T5693 |
nummod |
8,day |
| R3674 |
T5693 |
T5695 |
npadvmod |
day,old |
| R3675 |
T5694 |
T5693 |
punct |
-,day |
| R3676 |
T5695 |
T5696 |
amod |
old,animals |
| R3677 |
T5696 |
T5691 |
pobj |
animals,of |
| R3678 |
T5697 |
T5698 |
punct |
(,4 |
| R3679 |
T5698 |
T5665 |
parataxis |
4,preserve |
| R3680 |
T5699 |
T5698 |
nmod |
Figs.,4 |
| R3681 |
T5700 |
T5698 |
nummod |
3,4 |
| R3682 |
T5701 |
T5698 |
punct |
", ",4 |
| R3683 |
T5702 |
T5698 |
punct |
),4 |
| R3684 |
T5703 |
T5665 |
punct |
.,preserve |