| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T820 |
11-16 |
NN |
denotes |
Brn3c |
| T821 |
17-19 |
VBZ |
denotes |
is |
| T822 |
20-21 |
DT |
denotes |
a |
| T823 |
33-39 |
NN |
denotes |
factor |
| T824 |
22-25 |
NN |
denotes |
POU |
| T825 |
26-32 |
NN |
denotes |
domain |
| T826 |
40-44 |
WDT |
denotes |
that |
| T827 |
45-47 |
VBZ |
denotes |
is |
| T828 |
48-55 |
JJ |
denotes |
crucial |
| T829 |
56-59 |
IN |
denotes |
for |
| T830 |
60-65 |
JJ |
denotes |
inner |
| T831 |
66-69 |
JJ |
denotes |
ear |
| T832 |
80-91 |
NN |
denotes |
development |
| T833 |
70-74 |
NN |
denotes |
hair |
| T834 |
75-79 |
NN |
denotes |
cell |
| T835 |
91-92 |
. |
denotes |
. |
| T836 |
92-153 |
sentence |
denotes |
Targeted null Brn3c mutants have no mature hair cells [1,2]. |
| T837 |
93-101 |
VBN |
denotes |
Targeted |
| T838 |
113-120 |
NNS |
denotes |
mutants |
| T839 |
102-106 |
JJ |
denotes |
null |
| T840 |
107-112 |
NN |
denotes |
Brn3c |
| T841 |
121-125 |
VBP |
denotes |
have |
| T842 |
126-128 |
DT |
denotes |
no |
| T843 |
141-146 |
NNS |
denotes |
cells |
| T844 |
129-135 |
JJ |
denotes |
mature |
| T845 |
136-140 |
NN |
denotes |
hair |
| T846 |
147-148 |
-LRB- |
denotes |
[ |
| T847 |
150-151 |
CD |
denotes |
2 |
| T848 |
148-149 |
CD |
denotes |
1 |
| T849 |
149-150 |
, |
denotes |
, |
| T850 |
151-152 |
-RRB- |
denotes |
] |
| T851 |
152-153 |
. |
denotes |
. |
| T852 |
153-332 |
sentence |
denotes |
Close examination has revealed that some 'immature' hair cells form in Brn3c null mutants and express cellular markers such as Myosin VI and VIIa, calretinin and parvalbumin [3]. |
| T853 |
154-159 |
NN |
denotes |
Close |
| T854 |
160-171 |
NN |
denotes |
examination |
| T855 |
176-184 |
VBN |
denotes |
revealed |
| T856 |
172-175 |
VBZ |
denotes |
has |
| T857 |
185-189 |
IN |
denotes |
that |
| T858 |
217-221 |
VBP |
denotes |
form |
| T859 |
190-194 |
DT |
denotes |
some |
| T860 |
211-216 |
NNS |
denotes |
cells |
| T861 |
195-196 |
`` |
denotes |
' |
| T862 |
196-204 |
JJ |
denotes |
immature |
| T863 |
204-205 |
'' |
denotes |
' |
| T864 |
206-210 |
NN |
denotes |
hair |
| T865 |
222-224 |
IN |
denotes |
in |
| T866 |
225-230 |
NN |
denotes |
Brn3c |
| T867 |
236-243 |
NNS |
denotes |
mutants |
| T868 |
231-235 |
JJ |
denotes |
null |
| T869 |
244-247 |
CC |
denotes |
and |
| T870 |
248-255 |
VBP |
denotes |
express |
| T871 |
256-264 |
JJ |
denotes |
cellular |
| T872 |
265-272 |
NNS |
denotes |
markers |
| T873 |
273-277 |
JJ |
denotes |
such |
| T874 |
278-280 |
IN |
denotes |
as |
| T875 |
281-287 |
NN |
denotes |
Myosin |
| T876 |
288-290 |
NN |
denotes |
VI |
| T877 |
291-294 |
CC |
denotes |
and |
| T878 |
295-299 |
NN |
denotes |
VIIa |
| T879 |
299-301 |
, |
denotes |
, |
| T880 |
301-311 |
NN |
denotes |
calretinin |
| T881 |
312-315 |
CC |
denotes |
and |
| T882 |
316-327 |
NN |
denotes |
parvalbumin |
| T883 |
328-329 |
-LRB- |
denotes |
[ |
| T884 |
329-330 |
CD |
denotes |
3 |
| T885 |
330-331 |
-RRB- |
denotes |
] |
| T886 |
331-332 |
. |
denotes |
. |
| T887 |
332-428 |
sentence |
denotes |
Furthermore, these immature hair cells of Brn3c null mutants undergo apoptosis in neonates [3]. |
| T888 |
333-344 |
RB |
denotes |
Furthermore |
| T889 |
394-401 |
VBP |
denotes |
undergo |
| T890 |
344-346 |
, |
denotes |
, |
| T891 |
346-351 |
DT |
denotes |
these |
| T892 |
366-371 |
NNS |
denotes |
cells |
| T893 |
352-360 |
JJ |
denotes |
immature |
| T894 |
361-365 |
NN |
denotes |
hair |
| T895 |
372-374 |
IN |
denotes |
of |
| T896 |
375-380 |
NN |
denotes |
Brn3c |
| T897 |
386-393 |
NNS |
denotes |
mutants |
| T898 |
381-385 |
JJ |
denotes |
null |
| T899 |
402-411 |
NN |
denotes |
apoptosis |
| T900 |
412-414 |
IN |
denotes |
in |
| T901 |
415-423 |
NNS |
denotes |
neonates |
| T902 |
424-425 |
-LRB- |
denotes |
[ |
| T903 |
425-426 |
CD |
denotes |
3 |
| T904 |
426-427 |
-RRB- |
denotes |
] |
| T905 |
427-428 |
. |
denotes |
. |
| T906 |
428-601 |
sentence |
denotes |
Consistent with an apparent absence of mature hair cells, initial work suggested that all vestibular and most spiral ganglion cells are lost by postnatal day 14 (P14; [1]). |
| T907 |
429-439 |
JJ |
denotes |
Consistent |
| T908 |
500-509 |
VBD |
denotes |
suggested |
| T909 |
440-444 |
IN |
denotes |
with |
| T910 |
445-447 |
DT |
denotes |
an |
| T911 |
457-464 |
NN |
denotes |
absence |
| T912 |
448-456 |
JJ |
denotes |
apparent |
| T913 |
465-467 |
IN |
denotes |
of |
| T914 |
468-474 |
JJ |
denotes |
mature |
| T915 |
480-485 |
NNS |
denotes |
cells |
| T916 |
475-479 |
NN |
denotes |
hair |
| T917 |
485-487 |
, |
denotes |
, |
| T918 |
487-494 |
JJ |
denotes |
initial |
| T919 |
495-499 |
NN |
denotes |
work |
| T920 |
510-514 |
IN |
denotes |
that |
| T921 |
565-569 |
VBN |
denotes |
lost |
| T922 |
515-518 |
DT |
denotes |
all |
| T923 |
519-529 |
JJ |
denotes |
vestibular |
| T924 |
530-533 |
CC |
denotes |
and |
| T925 |
534-538 |
DT |
denotes |
most |
| T926 |
539-545 |
JJ |
denotes |
spiral |
| T927 |
555-560 |
NNS |
denotes |
cells |
| T928 |
546-554 |
NN |
denotes |
ganglion |
| T929 |
561-564 |
VBP |
denotes |
are |
| T930 |
570-572 |
IN |
denotes |
by |
| T931 |
573-582 |
JJ |
denotes |
postnatal |
| T932 |
583-586 |
NN |
denotes |
day |
| T933 |
587-589 |
CD |
denotes |
14 |
| T934 |
590-591 |
-LRB- |
denotes |
( |
| T935 |
591-594 |
NN |
denotes |
P14 |
| T936 |
594-595 |
: |
denotes |
; |
| T937 |
596-597 |
-LRB- |
denotes |
[ |
| T938 |
597-598 |
CD |
denotes |
1 |
| T939 |
598-599 |
-RRB- |
denotes |
] |
| T940 |
599-600 |
-RRB- |
denotes |
) |
| T941 |
600-601 |
. |
denotes |
. |
| T942 |
601-746 |
sentence |
denotes |
However, more detailed quantification by others [3] reported that at P4 about 77% of vestibular neurons and only 29% of spiral neurons are lost. |
| T943 |
602-609 |
RB |
denotes |
However |
| T944 |
654-662 |
VBD |
denotes |
reported |
| T945 |
609-611 |
, |
denotes |
, |
| T946 |
611-615 |
RBR |
denotes |
more |
| T947 |
625-639 |
NN |
denotes |
quantification |
| T948 |
616-624 |
JJ |
denotes |
detailed |
| T949 |
640-642 |
IN |
denotes |
by |
| T950 |
643-649 |
NNS |
denotes |
others |
| T951 |
650-651 |
-LRB- |
denotes |
[ |
| T952 |
651-652 |
CD |
denotes |
3 |
| T953 |
652-653 |
-RRB- |
denotes |
] |
| T954 |
663-667 |
IN |
denotes |
that |
| T955 |
741-745 |
VBN |
denotes |
lost |
| T956 |
668-670 |
IN |
denotes |
at |
| T957 |
671-673 |
NN |
denotes |
P4 |
| T958 |
674-679 |
IN |
denotes |
about |
| T959 |
680-682 |
CD |
denotes |
77 |
| T960 |
682-683 |
NN |
denotes |
% |
| T961 |
684-686 |
IN |
denotes |
of |
| T962 |
687-697 |
JJ |
denotes |
vestibular |
| T963 |
698-705 |
NNS |
denotes |
neurons |
| T964 |
706-709 |
CC |
denotes |
and |
| T965 |
710-714 |
RB |
denotes |
only |
| T966 |
715-717 |
CD |
denotes |
29 |
| T967 |
717-718 |
NN |
denotes |
% |
| T968 |
719-721 |
IN |
denotes |
of |
| T969 |
722-728 |
JJ |
denotes |
spiral |
| T970 |
729-736 |
NNS |
denotes |
neurons |
| T971 |
737-740 |
VBP |
denotes |
are |
| T972 |
745-746 |
. |
denotes |
. |
| T973 |
746-817 |
sentence |
denotes |
It was suggested that there is possibly a complete loss in adults [3]. |
| T974 |
747-749 |
PRP |
denotes |
It |
| T975 |
754-763 |
VBN |
denotes |
suggested |
| T976 |
750-753 |
VBD |
denotes |
was |
| T977 |
764-768 |
IN |
denotes |
that |
| T978 |
775-777 |
VBZ |
denotes |
is |
| T979 |
769-774 |
EX |
denotes |
there |
| T980 |
778-786 |
RB |
denotes |
possibly |
| T981 |
787-788 |
DT |
denotes |
a |
| T982 |
798-802 |
NN |
denotes |
loss |
| T983 |
789-797 |
JJ |
denotes |
complete |
| T984 |
803-805 |
IN |
denotes |
in |
| T985 |
806-812 |
NNS |
denotes |
adults |
| T986 |
813-814 |
-LRB- |
denotes |
[ |
| T987 |
814-815 |
CD |
denotes |
3 |
| T988 |
815-816 |
-RRB- |
denotes |
] |
| T989 |
816-817 |
. |
denotes |
. |
| T990 |
817-951 |
sentence |
denotes |
Other than these preliminary statements, no data exists concerning the detailed pattern of loss of innervation in Brn3c null mutants. |
| T991 |
818-823 |
RB |
denotes |
Other |
| T992 |
867-873 |
VBZ |
denotes |
exists |
| T993 |
824-828 |
IN |
denotes |
than |
| T994 |
829-834 |
DT |
denotes |
these |
| T995 |
847-857 |
NNS |
denotes |
statements |
| T996 |
835-846 |
JJ |
denotes |
preliminary |
| T997 |
857-859 |
, |
denotes |
, |
| T998 |
859-861 |
DT |
denotes |
no |
| T999 |
862-866 |
NN |
denotes |
data |
| T1000 |
874-884 |
VBG |
denotes |
concerning |
| T1001 |
885-888 |
DT |
denotes |
the |
| T1002 |
898-905 |
NN |
denotes |
pattern |
| T1003 |
889-897 |
JJ |
denotes |
detailed |
| T1004 |
906-908 |
IN |
denotes |
of |
| T1005 |
909-913 |
NN |
denotes |
loss |
| T1006 |
914-916 |
IN |
denotes |
of |
| T1007 |
917-928 |
NN |
denotes |
innervation |
| T1008 |
929-931 |
IN |
denotes |
in |
| T1009 |
932-937 |
NN |
denotes |
Brn3c |
| T1010 |
938-942 |
JJ |
denotes |
null |
| T1011 |
943-950 |
NNS |
denotes |
mutants |
| T1012 |
950-951 |
. |
denotes |
. |
| T1013 |
951-1170 |
sentence |
denotes |
The initial development and partial differentiation of hair cells in Brn3c mutants could possibly lead to some neurotrophin expression in these cells to sustain sensory neurons through embryonic development and beyond. |
| T1014 |
952-955 |
DT |
denotes |
The |
| T1015 |
964-975 |
NN |
denotes |
development |
| T1016 |
956-963 |
JJ |
denotes |
initial |
| T1017 |
1050-1054 |
VB |
denotes |
lead |
| T1018 |
976-979 |
CC |
denotes |
and |
| T1019 |
980-987 |
JJ |
denotes |
partial |
| T1020 |
988-1003 |
NN |
denotes |
differentiation |
| T1021 |
1004-1006 |
IN |
denotes |
of |
| T1022 |
1007-1011 |
NN |
denotes |
hair |
| T1023 |
1012-1017 |
NNS |
denotes |
cells |
| T1024 |
1018-1020 |
IN |
denotes |
in |
| T1025 |
1021-1026 |
NN |
denotes |
Brn3c |
| T1026 |
1027-1034 |
NNS |
denotes |
mutants |
| T1027 |
1035-1040 |
MD |
denotes |
could |
| T1028 |
1041-1049 |
RB |
denotes |
possibly |
| T1029 |
1055-1057 |
IN |
denotes |
to |
| T1030 |
1058-1062 |
DT |
denotes |
some |
| T1031 |
1076-1086 |
NN |
denotes |
expression |
| T1032 |
1063-1075 |
NN |
denotes |
neurotrophin |
| T1033 |
1087-1089 |
IN |
denotes |
in |
| T1034 |
1090-1095 |
DT |
denotes |
these |
| T1035 |
1096-1101 |
NNS |
denotes |
cells |
| T1036 |
1102-1104 |
TO |
denotes |
to |
| T1037 |
1105-1112 |
VB |
denotes |
sustain |
| T1038 |
1113-1120 |
JJ |
denotes |
sensory |
| T1039 |
1121-1128 |
NNS |
denotes |
neurons |
| T1040 |
1129-1136 |
IN |
denotes |
through |
| T1041 |
1137-1146 |
JJ |
denotes |
embryonic |
| T1042 |
1147-1158 |
NN |
denotes |
development |
| T1043 |
1159-1162 |
CC |
denotes |
and |
| T1044 |
1163-1169 |
RB |
denotes |
beyond |
| T1045 |
1169-1170 |
. |
denotes |
. |
| T1046 |
1170-1370 |
sentence |
denotes |
Data on various single and compound neurotrophin null mutants have shown that the loss of a specific neurotrophin leads to topologically restricted loss of sensory neurons in the embryonic ear [4,5]. |
| T1047 |
1171-1175 |
NNS |
denotes |
Data |
| T1048 |
1238-1243 |
VBN |
denotes |
shown |
| T1049 |
1176-1178 |
IN |
denotes |
on |
| T1050 |
1179-1186 |
JJ |
denotes |
various |
| T1051 |
1225-1232 |
NNS |
denotes |
mutants |
| T1052 |
1187-1193 |
JJ |
denotes |
single |
| T1053 |
1207-1219 |
NN |
denotes |
neurotrophin |
| T1054 |
1194-1197 |
CC |
denotes |
and |
| T1055 |
1198-1206 |
NN |
denotes |
compound |
| T1056 |
1220-1224 |
JJ |
denotes |
null |
| T1057 |
1233-1237 |
VBP |
denotes |
have |
| T1058 |
1244-1248 |
IN |
denotes |
that |
| T1059 |
1285-1290 |
VBZ |
denotes |
leads |
| T1060 |
1249-1252 |
DT |
denotes |
the |
| T1061 |
1253-1257 |
NN |
denotes |
loss |
| T1062 |
1258-1260 |
IN |
denotes |
of |
| T1063 |
1261-1262 |
DT |
denotes |
a |
| T1064 |
1272-1284 |
NN |
denotes |
neurotrophin |
| T1065 |
1263-1271 |
JJ |
denotes |
specific |
| T1066 |
1291-1293 |
IN |
denotes |
to |
| T1067 |
1294-1307 |
RB |
denotes |
topologically |
| T1068 |
1308-1318 |
JJ |
denotes |
restricted |
| T1069 |
1319-1323 |
NN |
denotes |
loss |
| T1070 |
1324-1326 |
IN |
denotes |
of |
| T1071 |
1327-1334 |
JJ |
denotes |
sensory |
| T1072 |
1335-1342 |
NNS |
denotes |
neurons |
| T1073 |
1343-1345 |
IN |
denotes |
in |
| T1074 |
1346-1349 |
DT |
denotes |
the |
| T1075 |
1360-1363 |
NN |
denotes |
ear |
| T1076 |
1350-1359 |
JJ |
denotes |
embryonic |
| T1077 |
1364-1365 |
-LRB- |
denotes |
[ |
| T1078 |
1367-1368 |
CD |
denotes |
5 |
| T1079 |
1365-1366 |
CD |
denotes |
4 |
| T1080 |
1366-1367 |
, |
denotes |
, |
| T1081 |
1368-1369 |
-RRB- |
denotes |
] |
| T1082 |
1369-1370 |
. |
denotes |
. |
| T1083 |
1370-1498 |
sentence |
denotes |
Such selective loss in Brn3c null mutants would therefore indicate reduction of a specific neurotrophin in immature hair cells. |
| T1084 |
1371-1375 |
JJ |
denotes |
Such |
| T1085 |
1386-1390 |
NN |
denotes |
loss |
| T1086 |
1376-1385 |
JJ |
denotes |
selective |
| T1087 |
1429-1437 |
VB |
denotes |
indicate |
| T1088 |
1391-1393 |
IN |
denotes |
in |
| T1089 |
1394-1399 |
NN |
denotes |
Brn3c |
| T1090 |
1405-1412 |
NNS |
denotes |
mutants |
| T1091 |
1400-1404 |
JJ |
denotes |
null |
| T1092 |
1413-1418 |
MD |
denotes |
would |
| T1093 |
1419-1428 |
RB |
denotes |
therefore |
| T1094 |
1438-1447 |
NN |
denotes |
reduction |
| T1095 |
1448-1450 |
IN |
denotes |
of |
| T1096 |
1451-1452 |
DT |
denotes |
a |
| T1097 |
1462-1474 |
NN |
denotes |
neurotrophin |
| T1098 |
1453-1461 |
JJ |
denotes |
specific |
| T1099 |
1475-1477 |
IN |
denotes |
in |
| T1100 |
1478-1486 |
JJ |
denotes |
immature |
| T1101 |
1492-1497 |
NNS |
denotes |
cells |
| T1102 |
1487-1491 |
NN |
denotes |
hair |
| T1103 |
1497-1498 |
. |
denotes |
. |
| T1104 |
1498-1639 |
sentence |
denotes |
Moreover, recent work shows that in embryos NT-3 is primarily expressed in supporting cells, moving only around birth into hair cells [6,7]. |
| T1105 |
1499-1507 |
RB |
denotes |
Moreover |
| T1106 |
1521-1526 |
VBZ |
denotes |
shows |
| T1107 |
1507-1509 |
, |
denotes |
, |
| T1108 |
1509-1515 |
JJ |
denotes |
recent |
| T1109 |
1516-1520 |
NN |
denotes |
work |
| T1110 |
1527-1531 |
IN |
denotes |
that |
| T1111 |
1561-1570 |
VBN |
denotes |
expressed |
| T1112 |
1532-1534 |
IN |
denotes |
in |
| T1113 |
1535-1542 |
NNS |
denotes |
embryos |
| T1114 |
1543-1545 |
NN |
denotes |
NT |
| T1115 |
1545-1546 |
HYPH |
denotes |
- |
| T1116 |
1546-1547 |
CD |
denotes |
3 |
| T1117 |
1548-1550 |
VBZ |
denotes |
is |
| T1118 |
1551-1560 |
RB |
denotes |
primarily |
| T1119 |
1571-1573 |
IN |
denotes |
in |
| T1120 |
1574-1584 |
VBG |
denotes |
supporting |
| T1121 |
1585-1590 |
NNS |
denotes |
cells |
| T1122 |
1590-1592 |
, |
denotes |
, |
| T1123 |
1592-1598 |
VBG |
denotes |
moving |
| T1124 |
1599-1603 |
RB |
denotes |
only |
| T1125 |
1604-1610 |
IN |
denotes |
around |
| T1126 |
1611-1616 |
NN |
denotes |
birth |
| T1127 |
1617-1621 |
IN |
denotes |
into |
| T1128 |
1622-1626 |
NN |
denotes |
hair |
| T1129 |
1627-1632 |
NNS |
denotes |
cells |
| T1130 |
1633-1634 |
-LRB- |
denotes |
[ |
| T1131 |
1636-1637 |
CD |
denotes |
7 |
| T1132 |
1634-1635 |
CD |
denotes |
6 |
| T1133 |
1635-1636 |
, |
denotes |
, |
| T1134 |
1637-1638 |
-RRB- |
denotes |
] |
| T1135 |
1638-1639 |
. |
denotes |
. |
| T1136 |
1639-1917 |
sentence |
denotes |
In fact, the selective loss of vestibular as compared to cochlear sensory neurons (77% versus 29%; [3]) suggests that NT-3 expression may be less downregulated in Brn3c null mutants than BDNF [6,8,9], provided that at least some differentiation of supporting cells takes place. |
| T1137 |
1640-1642 |
IN |
denotes |
In |
| T1138 |
1744-1752 |
VBZ |
denotes |
suggests |
| T1139 |
1643-1647 |
NN |
denotes |
fact |
| T1140 |
1647-1649 |
, |
denotes |
, |
| T1141 |
1649-1652 |
DT |
denotes |
the |
| T1142 |
1663-1667 |
NN |
denotes |
loss |
| T1143 |
1653-1662 |
JJ |
denotes |
selective |
| T1144 |
1668-1670 |
IN |
denotes |
of |
| T1145 |
1671-1681 |
JJ |
denotes |
vestibular |
| T1146 |
1682-1684 |
IN |
denotes |
as |
| T1147 |
1685-1693 |
VBN |
denotes |
compared |
| T1148 |
1694-1696 |
IN |
denotes |
to |
| T1149 |
1697-1705 |
JJ |
denotes |
cochlear |
| T1150 |
1706-1713 |
JJ |
denotes |
sensory |
| T1151 |
1714-1721 |
NNS |
denotes |
neurons |
| T1152 |
1722-1723 |
-LRB- |
denotes |
( |
| T1153 |
1725-1726 |
NN |
denotes |
% |
| T1154 |
1723-1725 |
CD |
denotes |
77 |
| T1155 |
1727-1733 |
CC |
denotes |
versus |
| T1156 |
1734-1736 |
CD |
denotes |
29 |
| T1157 |
1736-1737 |
NN |
denotes |
% |
| T1158 |
1737-1738 |
: |
denotes |
; |
| T1159 |
1739-1740 |
-LRB- |
denotes |
[ |
| T1160 |
1740-1741 |
CD |
denotes |
3 |
| T1161 |
1741-1742 |
-RRB- |
denotes |
] |
| T1162 |
1742-1743 |
-RRB- |
denotes |
) |
| T1163 |
1753-1757 |
IN |
denotes |
that |
| T1164 |
1778-1780 |
VB |
denotes |
be |
| T1165 |
1758-1760 |
NN |
denotes |
NT |
| T1166 |
1763-1773 |
NN |
denotes |
expression |
| T1167 |
1760-1761 |
HYPH |
denotes |
- |
| T1168 |
1761-1762 |
CD |
denotes |
3 |
| T1169 |
1774-1777 |
MD |
denotes |
may |
| T1170 |
1781-1785 |
RBR |
denotes |
less |
| T1171 |
1786-1799 |
VBN |
denotes |
downregulated |
| T1172 |
1800-1802 |
IN |
denotes |
in |
| T1173 |
1803-1808 |
NN |
denotes |
Brn3c |
| T1174 |
1814-1821 |
NNS |
denotes |
mutants |
| T1175 |
1809-1813 |
JJ |
denotes |
null |
| T1176 |
1822-1826 |
IN |
denotes |
than |
| T1177 |
1827-1831 |
NN |
denotes |
BDNF |
| T1178 |
1832-1833 |
-LRB- |
denotes |
[ |
| T1179 |
1837-1838 |
CD |
denotes |
9 |
| T1180 |
1833-1834 |
CD |
denotes |
6 |
| T1181 |
1834-1835 |
, |
denotes |
, |
| T1182 |
1835-1836 |
CD |
denotes |
8 |
| T1183 |
1836-1837 |
, |
denotes |
, |
| T1184 |
1838-1839 |
-RRB- |
denotes |
] |
| T1185 |
1839-1841 |
, |
denotes |
, |
| T1186 |
1841-1849 |
VBN |
denotes |
provided |
| T1187 |
1850-1854 |
IN |
denotes |
that |
| T1188 |
1905-1910 |
VBZ |
denotes |
takes |
| T1189 |
1855-1857 |
RB |
denotes |
at |
| T1190 |
1858-1863 |
RBS |
denotes |
least |
| T1191 |
1869-1884 |
NN |
denotes |
differentiation |
| T1192 |
1864-1868 |
DT |
denotes |
some |
| T1193 |
1885-1887 |
IN |
denotes |
of |
| T1194 |
1888-1898 |
VBG |
denotes |
supporting |
| T1195 |
1899-1904 |
NNS |
denotes |
cells |
| T1196 |
1911-1916 |
NN |
denotes |
place |
| T1197 |
1916-1917 |
. |
denotes |
. |
| T1198 |
1917-2070 |
sentence |
denotes |
In the ear [4] as well as elsewhere [10] neurotrophins are progressively downregulated in postnatal mammals and possibly replaced by other factors [11]. |
| T1199 |
1918-1920 |
IN |
denotes |
In |
| T1200 |
1991-2004 |
VBN |
denotes |
downregulated |
| T1201 |
1921-1924 |
DT |
denotes |
the |
| T1202 |
1925-1928 |
NN |
denotes |
ear |
| T1203 |
1929-1930 |
-LRB- |
denotes |
[ |
| T1204 |
1930-1931 |
CD |
denotes |
4 |
| T1205 |
1931-1932 |
-RRB- |
denotes |
] |
| T1206 |
1933-1935 |
RB |
denotes |
as |
| T1207 |
1941-1943 |
IN |
denotes |
as |
| T1208 |
1936-1940 |
RB |
denotes |
well |
| T1209 |
1944-1953 |
RB |
denotes |
elsewhere |
| T1210 |
1955-1957 |
CD |
denotes |
10 |
| T1211 |
1954-1955 |
-LRB- |
denotes |
[ |
| T1212 |
1957-1958 |
-RRB- |
denotes |
] |
| T1213 |
1959-1972 |
NNS |
denotes |
neurotrophins |
| T1214 |
1973-1976 |
VBP |
denotes |
are |
| T1215 |
1977-1990 |
RB |
denotes |
progressively |
| T1216 |
2005-2007 |
IN |
denotes |
in |
| T1217 |
2008-2017 |
JJ |
denotes |
postnatal |
| T1218 |
2018-2025 |
NNS |
denotes |
mammals |
| T1219 |
2026-2029 |
CC |
denotes |
and |
| T1220 |
2030-2038 |
RB |
denotes |
possibly |
| T1221 |
2039-2047 |
VBN |
denotes |
replaced |
| T1222 |
2048-2050 |
IN |
denotes |
by |
| T1223 |
2051-2056 |
JJ |
denotes |
other |
| T1224 |
2057-2064 |
NNS |
denotes |
factors |
| T1225 |
2065-2066 |
-LRB- |
denotes |
[ |
| T1226 |
2066-2068 |
CD |
denotes |
11 |
| T1227 |
2068-2069 |
-RRB- |
denotes |
] |
| T1228 |
2069-2070 |
. |
denotes |
. |
| T1229 |
2070-2194 |
sentence |
denotes |
We have investigated in detail the pattern of innervation in the Brn3c mutants, as well as the expression of NT-3 and BDNF. |
| T1230 |
2071-2073 |
PRP |
denotes |
We |
| T1231 |
2079-2091 |
VBN |
denotes |
investigated |
| T1232 |
2074-2078 |
VBP |
denotes |
have |
| T1233 |
2092-2094 |
IN |
denotes |
in |
| T1234 |
2095-2101 |
NN |
denotes |
detail |
| T1235 |
2102-2105 |
DT |
denotes |
the |
| T1236 |
2106-2113 |
NN |
denotes |
pattern |
| T1237 |
2114-2116 |
IN |
denotes |
of |
| T1238 |
2117-2128 |
NN |
denotes |
innervation |
| T1239 |
2129-2131 |
IN |
denotes |
in |
| T1240 |
2132-2135 |
DT |
denotes |
the |
| T1241 |
2142-2149 |
NNS |
denotes |
mutants |
| T1242 |
2136-2141 |
NN |
denotes |
Brn3c |
| T1243 |
2149-2151 |
, |
denotes |
, |
| T1244 |
2151-2153 |
RB |
denotes |
as |
| T1245 |
2159-2161 |
IN |
denotes |
as |
| T1246 |
2154-2158 |
RB |
denotes |
well |
| T1247 |
2162-2165 |
DT |
denotes |
the |
| T1248 |
2166-2176 |
NN |
denotes |
expression |
| T1249 |
2177-2179 |
IN |
denotes |
of |
| T1250 |
2180-2182 |
NN |
denotes |
NT |
| T1251 |
2182-2183 |
HYPH |
denotes |
- |
| T1252 |
2183-2184 |
CD |
denotes |
3 |
| T1253 |
2185-2188 |
CC |
denotes |
and |
| T1254 |
2189-2193 |
NN |
denotes |
BDNF |
| T1255 |
2193-2194 |
. |
denotes |
. |
| T1256 |
2194-2385 |
sentence |
denotes |
We want to evaluate a possible correlation between the topology of sensory neuron loss and absence of a specific neurotrophin or topological loss of hair cells at birth and in older animals. |
| T1257 |
2195-2197 |
PRP |
denotes |
We |
| T1258 |
2198-2202 |
VBP |
denotes |
want |
| T1259 |
2203-2205 |
TO |
denotes |
to |
| T1260 |
2206-2214 |
VB |
denotes |
evaluate |
| T1261 |
2215-2216 |
DT |
denotes |
a |
| T1262 |
2226-2237 |
NN |
denotes |
correlation |
| T1263 |
2217-2225 |
JJ |
denotes |
possible |
| T1264 |
2238-2245 |
IN |
denotes |
between |
| T1265 |
2246-2249 |
DT |
denotes |
the |
| T1266 |
2250-2258 |
NN |
denotes |
topology |
| T1267 |
2259-2261 |
IN |
denotes |
of |
| T1268 |
2262-2269 |
JJ |
denotes |
sensory |
| T1269 |
2270-2276 |
NN |
denotes |
neuron |
| T1270 |
2277-2281 |
NN |
denotes |
loss |
| T1271 |
2282-2285 |
CC |
denotes |
and |
| T1272 |
2286-2293 |
NN |
denotes |
absence |
| T1273 |
2294-2296 |
IN |
denotes |
of |
| T1274 |
2297-2298 |
DT |
denotes |
a |
| T1275 |
2308-2320 |
NN |
denotes |
neurotrophin |
| T1276 |
2299-2307 |
JJ |
denotes |
specific |
| T1277 |
2321-2323 |
CC |
denotes |
or |
| T1278 |
2324-2335 |
JJ |
denotes |
topological |
| T1279 |
2336-2340 |
NN |
denotes |
loss |
| T1280 |
2341-2343 |
IN |
denotes |
of |
| T1281 |
2344-2348 |
NN |
denotes |
hair |
| T1282 |
2349-2354 |
NNS |
denotes |
cells |
| T1283 |
2355-2357 |
IN |
denotes |
at |
| T1284 |
2358-2363 |
NN |
denotes |
birth |
| T1285 |
2364-2367 |
CC |
denotes |
and |
| T1286 |
2368-2370 |
IN |
denotes |
in |
| T1287 |
2371-2376 |
JJR |
denotes |
older |
| T1288 |
2377-2384 |
NNS |
denotes |
animals |
| T1289 |
2384-2385 |
. |
denotes |
. |
| T1290 |
2385-2511 |
sentence |
denotes |
This information could be important for an in-depth evaluation of the human deafness related to the Pou4f3 gene, DFNA15 [12]. |
| T1291 |
2386-2390 |
DT |
denotes |
This |
| T1292 |
2391-2402 |
NN |
denotes |
information |
| T1293 |
2409-2411 |
VB |
denotes |
be |
| T1294 |
2403-2408 |
MD |
denotes |
could |
| T1295 |
2412-2421 |
JJ |
denotes |
important |
| T1296 |
2422-2425 |
IN |
denotes |
for |
| T1297 |
2426-2428 |
DT |
denotes |
an |
| T1298 |
2438-2448 |
NN |
denotes |
evaluation |
| T1299 |
2429-2431 |
IN |
denotes |
in |
| T1300 |
2431-2432 |
HYPH |
denotes |
- |
| T1301 |
2432-2437 |
NN |
denotes |
depth |
| T1302 |
2449-2451 |
IN |
denotes |
of |
| T1303 |
2452-2455 |
DT |
denotes |
the |
| T1304 |
2462-2470 |
NN |
denotes |
deafness |
| T1305 |
2456-2461 |
JJ |
denotes |
human |
| T1306 |
2471-2478 |
VBN |
denotes |
related |
| T1307 |
2479-2481 |
IN |
denotes |
to |
| T1308 |
2482-2485 |
DT |
denotes |
the |
| T1309 |
2493-2497 |
NN |
denotes |
gene |
| T1310 |
2486-2492 |
NN |
denotes |
Pou4f3 |
| T1311 |
2497-2499 |
, |
denotes |
, |
| T1312 |
2499-2505 |
NN |
denotes |
DFNA15 |
| T1313 |
2506-2507 |
-LRB- |
denotes |
[ |
| T1314 |
2507-2509 |
CD |
denotes |
12 |
| T1315 |
2509-2510 |
-RRB- |
denotes |
] |
| T1316 |
2510-2511 |
. |
denotes |
. |
| T1317 |
2511-2660 |
sentence |
denotes |
We report here long term retention of cochlear sensory neurons for at least 6 months, in particular in the cochlear apex, in Brn3c null mutant mice. |
| T1318 |
2512-2514 |
PRP |
denotes |
We |
| T1319 |
2515-2521 |
VBP |
denotes |
report |
| T1320 |
2522-2526 |
RB |
denotes |
here |
| T1321 |
2527-2531 |
JJ |
denotes |
long |
| T1322 |
2532-2536 |
NN |
denotes |
term |
| T1323 |
2537-2546 |
NN |
denotes |
retention |
| T1324 |
2547-2549 |
IN |
denotes |
of |
| T1325 |
2550-2558 |
JJ |
denotes |
cochlear |
| T1326 |
2567-2574 |
NNS |
denotes |
neurons |
| T1327 |
2559-2566 |
JJ |
denotes |
sensory |
| T1328 |
2575-2578 |
IN |
denotes |
for |
| T1329 |
2579-2581 |
RB |
denotes |
at |
| T1330 |
2588-2589 |
CD |
denotes |
6 |
| T1331 |
2582-2587 |
RBS |
denotes |
least |
| T1332 |
2590-2596 |
NNS |
denotes |
months |
| T1333 |
2596-2598 |
, |
denotes |
, |
| T1334 |
2598-2600 |
IN |
denotes |
in |
| T1335 |
2612-2614 |
IN |
denotes |
in |
| T1336 |
2601-2611 |
JJ |
denotes |
particular |
| T1337 |
2615-2618 |
DT |
denotes |
the |
| T1338 |
2628-2632 |
NN |
denotes |
apex |
| T1339 |
2619-2627 |
JJ |
denotes |
cochlear |
| T1340 |
2632-2634 |
, |
denotes |
, |
| T1341 |
2634-2636 |
IN |
denotes |
in |
| T1342 |
2637-2642 |
NN |
denotes |
Brn3c |
| T1343 |
2643-2647 |
JJ |
denotes |
null |
| T1344 |
2655-2659 |
NNS |
denotes |
mice |
| T1345 |
2648-2654 |
JJ |
denotes |
mutant |
| T1346 |
2659-2660 |
. |
denotes |
. |
| T1347 |
2660-2879 |
sentence |
denotes |
This retention of afferents and efferents is unrelated to hair cell differentiation as not even immature hair cells can be detected at early postnatal stages with MyoVII immunocytochemistry in this part of the cochlea. |
| T1348 |
2661-2665 |
DT |
denotes |
This |
| T1349 |
2666-2675 |
NN |
denotes |
retention |
| T1350 |
2703-2705 |
VBZ |
denotes |
is |
| T1351 |
2676-2678 |
IN |
denotes |
of |
| T1352 |
2679-2688 |
NNS |
denotes |
afferents |
| T1353 |
2689-2692 |
CC |
denotes |
and |
| T1354 |
2693-2702 |
NNS |
denotes |
efferents |
| T1355 |
2706-2715 |
JJ |
denotes |
unrelated |
| T1356 |
2716-2718 |
IN |
denotes |
to |
| T1357 |
2719-2723 |
NN |
denotes |
hair |
| T1358 |
2724-2728 |
NN |
denotes |
cell |
| T1359 |
2729-2744 |
NN |
denotes |
differentiation |
| T1360 |
2745-2747 |
IN |
denotes |
as |
| T1361 |
2784-2792 |
VBN |
denotes |
detected |
| T1362 |
2748-2751 |
RB |
denotes |
not |
| T1363 |
2771-2776 |
NNS |
denotes |
cells |
| T1364 |
2752-2756 |
RB |
denotes |
even |
| T1365 |
2757-2765 |
JJ |
denotes |
immature |
| T1366 |
2766-2770 |
NN |
denotes |
hair |
| T1367 |
2777-2780 |
MD |
denotes |
can |
| T1368 |
2781-2783 |
VB |
denotes |
be |
| T1369 |
2793-2795 |
IN |
denotes |
at |
| T1370 |
2796-2801 |
JJ |
denotes |
early |
| T1371 |
2812-2818 |
NNS |
denotes |
stages |
| T1372 |
2802-2811 |
JJ |
denotes |
postnatal |
| T1373 |
2819-2823 |
IN |
denotes |
with |
| T1374 |
2824-2830 |
NN |
denotes |
MyoVII |
| T1375 |
2831-2850 |
NN |
denotes |
immunocytochemistry |
| T1376 |
2851-2853 |
IN |
denotes |
in |
| T1377 |
2854-2858 |
DT |
denotes |
this |
| T1378 |
2859-2863 |
NN |
denotes |
part |
| T1379 |
2864-2866 |
IN |
denotes |
of |
| T1380 |
2867-2870 |
DT |
denotes |
the |
| T1381 |
2871-2878 |
NN |
denotes |
cochlea |
| T1382 |
2878-2879 |
. |
denotes |
. |
| T1383 |
2879-3037 |
sentence |
denotes |
This retention of apical spiral neurons is also largely unrelated to neurotrophins which are known to be reduced in their expression in neonatal rodents [4]. |
| T1384 |
2880-2884 |
DT |
denotes |
This |
| T1385 |
2885-2894 |
NN |
denotes |
retention |
| T1386 |
2920-2922 |
VBZ |
denotes |
is |
| T1387 |
2895-2897 |
IN |
denotes |
of |
| T1388 |
2898-2904 |
JJ |
denotes |
apical |
| T1389 |
2912-2919 |
NNS |
denotes |
neurons |
| T1390 |
2905-2911 |
JJ |
denotes |
spiral |
| T1391 |
2923-2927 |
RB |
denotes |
also |
| T1392 |
2928-2935 |
RB |
denotes |
largely |
| T1393 |
2936-2945 |
JJ |
denotes |
unrelated |
| T1394 |
2946-2948 |
IN |
denotes |
to |
| T1395 |
2949-2962 |
NNS |
denotes |
neurotrophins |
| T1396 |
2963-2968 |
WDT |
denotes |
which |
| T1397 |
2973-2978 |
VBN |
denotes |
known |
| T1398 |
2969-2972 |
VBP |
denotes |
are |
| T1399 |
2979-2981 |
TO |
denotes |
to |
| T1400 |
2985-2992 |
VBN |
denotes |
reduced |
| T1401 |
2982-2984 |
VB |
denotes |
be |
| T1402 |
2993-2995 |
IN |
denotes |
in |
| T1403 |
2996-3001 |
PRP$ |
denotes |
their |
| T1404 |
3002-3012 |
NN |
denotes |
expression |
| T1405 |
3013-3015 |
IN |
denotes |
in |
| T1406 |
3016-3024 |
JJ |
denotes |
neonatal |
| T1407 |
3025-3032 |
NNS |
denotes |
rodents |
| T1408 |
3033-3034 |
-LRB- |
denotes |
[ |
| T1409 |
3034-3035 |
CD |
denotes |
4 |
| T1410 |
3035-3036 |
-RRB- |
denotes |
] |
| T1411 |
3036-3037 |
. |
denotes |
. |
| R300 |
T820 |
T821 |
nsubj |
Brn3c,is |
| R301 |
T822 |
T823 |
det |
a,factor |
| R302 |
T823 |
T821 |
attr |
factor,is |
| R303 |
T824 |
T825 |
compound |
POU,domain |
| R304 |
T825 |
T823 |
compound |
domain,factor |
| R305 |
T826 |
T827 |
dep |
that,is |
| R306 |
T827 |
T823 |
relcl |
is,factor |
| R307 |
T828 |
T827 |
acomp |
crucial,is |
| R308 |
T829 |
T828 |
prep |
for,crucial |
| R309 |
T830 |
T831 |
amod |
inner,ear |
| R310 |
T831 |
T832 |
nmod |
ear,development |
| R311 |
T832 |
T829 |
pobj |
development,for |
| R312 |
T833 |
T834 |
compound |
hair,cell |
| R313 |
T834 |
T832 |
compound |
cell,development |
| R314 |
T835 |
T821 |
punct |
.,is |
| R315 |
T837 |
T838 |
amod |
Targeted,mutants |
| R316 |
T838 |
T841 |
nsubj |
mutants,have |
| R317 |
T839 |
T838 |
amod |
null,mutants |
| R318 |
T840 |
T838 |
compound |
Brn3c,mutants |
| R319 |
T842 |
T843 |
det |
no,cells |
| R320 |
T843 |
T841 |
dobj |
cells,have |
| R321 |
T844 |
T843 |
amod |
mature,cells |
| R322 |
T845 |
T843 |
compound |
hair,cells |
| R323 |
T846 |
T847 |
punct |
[,2 |
| R324 |
T847 |
T841 |
parataxis |
2,have |
| R325 |
T848 |
T847 |
nummod |
1,2 |
| R326 |
T849 |
T847 |
punct |
",",2 |
| R327 |
T850 |
T847 |
punct |
],2 |
| R328 |
T851 |
T841 |
punct |
.,have |
| R329 |
T853 |
T854 |
compound |
Close,examination |
| R330 |
T854 |
T855 |
nsubj |
examination,revealed |
| R331 |
T856 |
T855 |
aux |
has,revealed |
| R332 |
T857 |
T858 |
mark |
that,form |
| R333 |
T858 |
T855 |
ccomp |
form,revealed |
| R334 |
T859 |
T860 |
det |
some,cells |
| R335 |
T860 |
T858 |
nsubj |
cells,form |
| R336 |
T861 |
T860 |
punct |
',cells |
| R337 |
T862 |
T860 |
amod |
immature,cells |
| R338 |
T863 |
T860 |
punct |
',cells |
| R339 |
T864 |
T860 |
compound |
hair,cells |
| R340 |
T865 |
T858 |
prep |
in,form |
| R341 |
T866 |
T867 |
nmod |
Brn3c,mutants |
| R342 |
T867 |
T865 |
pobj |
mutants,in |
| R343 |
T868 |
T867 |
amod |
null,mutants |
| R344 |
T869 |
T858 |
cc |
and,form |
| R345 |
T870 |
T858 |
conj |
express,form |
| R346 |
T871 |
T872 |
amod |
cellular,markers |
| R347 |
T872 |
T870 |
dobj |
markers,express |
| R348 |
T873 |
T874 |
amod |
such,as |
| R349 |
T874 |
T872 |
prep |
as,markers |
| R350 |
T875 |
T876 |
compound |
Myosin,VI |
| R351 |
T876 |
T874 |
pobj |
VI,as |
| R352 |
T877 |
T876 |
cc |
and,VI |
| R353 |
T878 |
T876 |
conj |
VIIa,VI |
| R354 |
T879 |
T876 |
punct |
", ",VI |
| R355 |
T880 |
T876 |
conj |
calretinin,VI |
| R356 |
T881 |
T880 |
cc |
and,calretinin |
| R357 |
T882 |
T880 |
conj |
parvalbumin,calretinin |
| R358 |
T883 |
T884 |
punct |
[,3 |
| R359 |
T884 |
T855 |
parataxis |
3,revealed |
| R360 |
T885 |
T884 |
punct |
],3 |
| R361 |
T886 |
T855 |
punct |
.,revealed |
| R362 |
T888 |
T889 |
advmod |
Furthermore,undergo |
| R363 |
T890 |
T889 |
punct |
", ",undergo |
| R364 |
T891 |
T892 |
det |
these,cells |
| R365 |
T892 |
T889 |
nsubj |
cells,undergo |
| R366 |
T893 |
T892 |
amod |
immature,cells |
| R367 |
T894 |
T892 |
compound |
hair,cells |
| R368 |
T895 |
T892 |
prep |
of,cells |
| R369 |
T896 |
T897 |
nmod |
Brn3c,mutants |
| R370 |
T897 |
T895 |
pobj |
mutants,of |
| R371 |
T898 |
T897 |
amod |
null,mutants |
| R372 |
T899 |
T889 |
dobj |
apoptosis,undergo |
| R373 |
T900 |
T889 |
prep |
in,undergo |
| R374 |
T901 |
T900 |
pobj |
neonates,in |
| R375 |
T902 |
T903 |
punct |
[,3 |
| R376 |
T903 |
T889 |
parataxis |
3,undergo |
| R377 |
T904 |
T903 |
punct |
],3 |
| R378 |
T905 |
T889 |
punct |
.,undergo |
| R379 |
T907 |
T908 |
advcl |
Consistent,suggested |
| R380 |
T909 |
T907 |
prep |
with,Consistent |
| R381 |
T910 |
T911 |
det |
an,absence |
| R382 |
T911 |
T909 |
pobj |
absence,with |
| R383 |
T912 |
T911 |
amod |
apparent,absence |
| R384 |
T913 |
T911 |
prep |
of,absence |
| R385 |
T914 |
T915 |
amod |
mature,cells |
| R386 |
T915 |
T913 |
pobj |
cells,of |
| R387 |
T916 |
T915 |
compound |
hair,cells |
| R388 |
T917 |
T908 |
punct |
", ",suggested |
| R389 |
T918 |
T919 |
amod |
initial,work |
| R390 |
T919 |
T908 |
nsubj |
work,suggested |
| R391 |
T920 |
T921 |
mark |
that,lost |
| R392 |
T921 |
T908 |
ccomp |
lost,suggested |
| R393 |
T922 |
T923 |
det |
all,vestibular |
| R394 |
T923 |
T921 |
nsubjpass |
vestibular,lost |
| R395 |
T924 |
T923 |
cc |
and,vestibular |
| R396 |
T925 |
T926 |
det |
most,spiral |
| R397 |
T926 |
T927 |
nmod |
spiral,cells |
| R398 |
T927 |
T923 |
conj |
cells,vestibular |
| R399 |
T928 |
T927 |
compound |
ganglion,cells |
| R400 |
T929 |
T921 |
auxpass |
are,lost |
| R401 |
T930 |
T921 |
prep |
by,lost |
| R402 |
T931 |
T932 |
amod |
postnatal,day |
| R403 |
T932 |
T930 |
pobj |
day,by |
| R404 |
T933 |
T932 |
nummod |
14,day |
| R405 |
T934 |
T932 |
punct |
(,day |
| R406 |
T935 |
T932 |
appos |
P14,day |
| R407 |
T936 |
T921 |
punct |
;,lost |
| R408 |
T937 |
T938 |
punct |
[,1 |
| R409 |
T938 |
T921 |
parataxis |
1,lost |
| R410 |
T939 |
T938 |
punct |
],1 |
| R411 |
T940 |
T921 |
punct |
),lost |
| R412 |
T941 |
T908 |
punct |
.,suggested |
| R413 |
T943 |
T944 |
advmod |
However,reported |
| R414 |
T945 |
T944 |
punct |
", ",reported |
| R415 |
T946 |
T947 |
advmod |
more,quantification |
| R416 |
T947 |
T944 |
nsubj |
quantification,reported |
| R417 |
T948 |
T947 |
amod |
detailed,quantification |
| R418 |
T949 |
T947 |
prep |
by,quantification |
| R419 |
T950 |
T949 |
pobj |
others,by |
| R420 |
T951 |
T952 |
punct |
[,3 |
| R421 |
T952 |
T947 |
parataxis |
3,quantification |
| R422 |
T953 |
T952 |
punct |
],3 |
| R423 |
T954 |
T955 |
mark |
that,lost |
| R424 |
T955 |
T944 |
ccomp |
lost,reported |
| R425 |
T956 |
T955 |
prep |
at,lost |
| R426 |
T957 |
T956 |
pobj |
P4,at |
| R427 |
T958 |
T959 |
quantmod |
about,77 |
| R428 |
T959 |
T960 |
nummod |
77,% |
| R429 |
T960 |
T955 |
nsubjpass |
%,lost |
| R430 |
T961 |
T960 |
prep |
of,% |
| R431 |
T962 |
T963 |
amod |
vestibular,neurons |
| R432 |
T963 |
T961 |
pobj |
neurons,of |
| R433 |
T964 |
T960 |
cc |
and,% |
| R434 |
T965 |
T966 |
advmod |
only,29 |
| R435 |
T966 |
T967 |
nummod |
29,% |
| R436 |
T967 |
T960 |
conj |
%,% |
| R437 |
T968 |
T967 |
prep |
of,% |
| R438 |
T969 |
T970 |
amod |
spiral,neurons |
| R439 |
T970 |
T968 |
pobj |
neurons,of |
| R440 |
T971 |
T955 |
auxpass |
are,lost |
| R441 |
T972 |
T944 |
punct |
.,reported |
| R442 |
T974 |
T975 |
nsubjpass |
It,suggested |
| R443 |
T976 |
T975 |
auxpass |
was,suggested |
| R444 |
T977 |
T978 |
mark |
that,is |
| R445 |
T978 |
T975 |
ccomp |
is,suggested |
| R446 |
T979 |
T978 |
expl |
there,is |
| R447 |
T980 |
T978 |
advmod |
possibly,is |
| R448 |
T981 |
T982 |
det |
a,loss |
| R449 |
T982 |
T978 |
attr |
loss,is |
| R450 |
T983 |
T982 |
amod |
complete,loss |
| R451 |
T984 |
T978 |
prep |
in,is |
| R452 |
T985 |
T984 |
pobj |
adults,in |
| R453 |
T986 |
T987 |
punct |
[,3 |
| R454 |
T987 |
T975 |
parataxis |
3,suggested |
| R455 |
T988 |
T987 |
punct |
],3 |
| R456 |
T989 |
T975 |
punct |
.,suggested |
| R457 |
T991 |
T992 |
advmod |
Other,exists |
| R458 |
T993 |
T991 |
prep |
than,Other |
| R459 |
T994 |
T995 |
det |
these,statements |
| R460 |
T995 |
T993 |
pobj |
statements,than |
| R461 |
T996 |
T995 |
amod |
preliminary,statements |
| R462 |
T997 |
T992 |
punct |
", ",exists |
| R463 |
T998 |
T999 |
det |
no,data |
| R464 |
T999 |
T992 |
nsubj |
data,exists |
| R465 |
T1000 |
T992 |
prep |
concerning,exists |
| R466 |
T1001 |
T1002 |
det |
the,pattern |
| R467 |
T1002 |
T1000 |
pobj |
pattern,concerning |
| R468 |
T1003 |
T1002 |
amod |
detailed,pattern |
| R469 |
T1004 |
T1002 |
prep |
of,pattern |
| R470 |
T1005 |
T1004 |
pobj |
loss,of |
| R471 |
T1006 |
T1005 |
prep |
of,loss |
| R472 |
T1007 |
T1006 |
pobj |
innervation,of |
| R473 |
T1008 |
T1005 |
prep |
in,loss |
| R474 |
T1009 |
T1010 |
npadvmod |
Brn3c,null |
| R475 |
T1010 |
T1011 |
amod |
null,mutants |
| R476 |
T1011 |
T1008 |
pobj |
mutants,in |
| R477 |
T1012 |
T992 |
punct |
.,exists |
| R478 |
T1014 |
T1015 |
det |
The,development |
| R479 |
T1015 |
T1017 |
nsubj |
development,lead |
| R480 |
T1016 |
T1015 |
amod |
initial,development |
| R481 |
T1018 |
T1015 |
cc |
and,development |
| R482 |
T1019 |
T1020 |
amod |
partial,differentiation |
| R483 |
T1020 |
T1015 |
conj |
differentiation,development |
| R484 |
T1021 |
T1015 |
prep |
of,development |
| R485 |
T1022 |
T1023 |
compound |
hair,cells |
| R486 |
T1023 |
T1021 |
pobj |
cells,of |
| R487 |
T1024 |
T1015 |
prep |
in,development |
| R488 |
T1025 |
T1026 |
compound |
Brn3c,mutants |
| R489 |
T1026 |
T1024 |
pobj |
mutants,in |
| R490 |
T1027 |
T1017 |
aux |
could,lead |
| R491 |
T1028 |
T1017 |
advmod |
possibly,lead |
| R492 |
T1029 |
T1017 |
prep |
to,lead |
| R493 |
T1030 |
T1031 |
det |
some,expression |
| R494 |
T1031 |
T1029 |
pobj |
expression,to |
| R495 |
T1032 |
T1031 |
compound |
neurotrophin,expression |
| R496 |
T1033 |
T1031 |
prep |
in,expression |
| R497 |
T1034 |
T1035 |
det |
these,cells |
| R498 |
T1035 |
T1033 |
pobj |
cells,in |
| R499 |
T1036 |
T1037 |
aux |
to,sustain |
| R500 |
T1037 |
T1017 |
advcl |
sustain,lead |
| R501 |
T1038 |
T1039 |
amod |
sensory,neurons |
| R502 |
T1039 |
T1037 |
dobj |
neurons,sustain |
| R503 |
T1040 |
T1037 |
prep |
through,sustain |
| R504 |
T1041 |
T1042 |
amod |
embryonic,development |
| R505 |
T1042 |
T1040 |
pobj |
development,through |
| R506 |
T1043 |
T1040 |
cc |
and,through |
| R507 |
T1044 |
T1040 |
conj |
beyond,through |
| R508 |
T1045 |
T1017 |
punct |
.,lead |
| R509 |
T1047 |
T1048 |
nsubj |
Data,shown |
| R510 |
T1049 |
T1047 |
prep |
on,Data |
| R511 |
T1050 |
T1051 |
amod |
various,mutants |
| R512 |
T1051 |
T1049 |
pobj |
mutants,on |
| R513 |
T1052 |
T1053 |
amod |
single,neurotrophin |
| R514 |
T1053 |
T1056 |
npadvmod |
neurotrophin,null |
| R515 |
T1054 |
T1052 |
cc |
and,single |
| R516 |
T1055 |
T1052 |
conj |
compound,single |
| R517 |
T1056 |
T1051 |
amod |
null,mutants |
| R518 |
T1057 |
T1048 |
aux |
have,shown |
| R519 |
T1058 |
T1059 |
mark |
that,leads |
| R520 |
T1059 |
T1048 |
ccomp |
leads,shown |
| R521 |
T1060 |
T1061 |
det |
the,loss |
| R522 |
T1061 |
T1059 |
nsubj |
loss,leads |
| R523 |
T1062 |
T1061 |
prep |
of,loss |
| R524 |
T1063 |
T1064 |
det |
a,neurotrophin |
| R525 |
T1064 |
T1062 |
pobj |
neurotrophin,of |
| R526 |
T1065 |
T1064 |
amod |
specific,neurotrophin |
| R527 |
T1066 |
T1059 |
prep |
to,leads |
| R528 |
T1067 |
T1068 |
advmod |
topologically,restricted |
| R529 |
T1068 |
T1069 |
amod |
restricted,loss |
| R530 |
T1069 |
T1066 |
pobj |
loss,to |
| R531 |
T1070 |
T1069 |
prep |
of,loss |
| R532 |
T1071 |
T1072 |
amod |
sensory,neurons |
| R533 |
T1072 |
T1070 |
pobj |
neurons,of |
| R534 |
T1073 |
T1069 |
prep |
in,loss |
| R535 |
T1074 |
T1075 |
det |
the,ear |
| R536 |
T1075 |
T1073 |
pobj |
ear,in |
| R537 |
T1076 |
T1075 |
amod |
embryonic,ear |
| R538 |
T1077 |
T1078 |
punct |
[,5 |
| R539 |
T1078 |
T1048 |
parataxis |
5,shown |
| R540 |
T1079 |
T1078 |
nummod |
4,5 |
| R541 |
T1080 |
T1078 |
punct |
",",5 |
| R542 |
T1081 |
T1078 |
punct |
],5 |
| R543 |
T1082 |
T1048 |
punct |
.,shown |
| R544 |
T1084 |
T1085 |
amod |
Such,loss |
| R545 |
T1085 |
T1087 |
nsubj |
loss,indicate |
| R546 |
T1086 |
T1085 |
amod |
selective,loss |
| R547 |
T1088 |
T1085 |
prep |
in,loss |
| R548 |
T1089 |
T1090 |
nmod |
Brn3c,mutants |
| R549 |
T1090 |
T1088 |
pobj |
mutants,in |
| R550 |
T1091 |
T1090 |
amod |
null,mutants |
| R551 |
T1092 |
T1087 |
aux |
would,indicate |
| R552 |
T1093 |
T1087 |
advmod |
therefore,indicate |
| R553 |
T1094 |
T1087 |
dobj |
reduction,indicate |
| R554 |
T1095 |
T1094 |
prep |
of,reduction |
| R555 |
T1096 |
T1097 |
det |
a,neurotrophin |
| R556 |
T1097 |
T1095 |
pobj |
neurotrophin,of |
| R557 |
T1098 |
T1097 |
amod |
specific,neurotrophin |
| R558 |
T1099 |
T1094 |
prep |
in,reduction |
| R559 |
T1100 |
T1101 |
amod |
immature,cells |
| R560 |
T1101 |
T1099 |
pobj |
cells,in |
| R561 |
T1102 |
T1101 |
compound |
hair,cells |
| R562 |
T1103 |
T1087 |
punct |
.,indicate |
| R563 |
T1105 |
T1106 |
advmod |
Moreover,shows |
| R564 |
T1107 |
T1106 |
punct |
", ",shows |
| R565 |
T1108 |
T1109 |
amod |
recent,work |
| R566 |
T1109 |
T1106 |
nsubj |
work,shows |
| R567 |
T1110 |
T1111 |
mark |
that,expressed |
| R568 |
T1111 |
T1106 |
ccomp |
expressed,shows |
| R569 |
T1112 |
T1111 |
prep |
in,expressed |
| R570 |
T1113 |
T1112 |
pobj |
embryos,in |
| R571 |
T1114 |
T1111 |
nsubjpass |
NT,expressed |
| R572 |
T1115 |
T1114 |
punct |
-,NT |
| R573 |
T1116 |
T1114 |
nummod |
3,NT |
| R574 |
T1117 |
T1111 |
auxpass |
is,expressed |
| R575 |
T1118 |
T1111 |
advmod |
primarily,expressed |
| R576 |
T1119 |
T1111 |
prep |
in,expressed |
| R577 |
T1120 |
T1121 |
amod |
supporting,cells |
| R578 |
T1121 |
T1119 |
pobj |
cells,in |
| R579 |
T1122 |
T1111 |
punct |
", ",expressed |
| R580 |
T1123 |
T1111 |
advcl |
moving,expressed |
| R581 |
T1124 |
T1125 |
advmod |
only,around |
| R582 |
T1125 |
T1123 |
prep |
around,moving |
| R583 |
T1126 |
T1125 |
pobj |
birth,around |
| R584 |
T1127 |
T1123 |
prep |
into,moving |
| R585 |
T1128 |
T1129 |
compound |
hair,cells |
| R586 |
T1129 |
T1127 |
pobj |
cells,into |
| R587 |
T1130 |
T1131 |
punct |
[,7 |
| R588 |
T1131 |
T1106 |
parataxis |
7,shows |
| R589 |
T1132 |
T1131 |
nummod |
6,7 |
| R590 |
T1133 |
T1131 |
punct |
",",7 |
| R591 |
T1134 |
T1131 |
punct |
],7 |
| R592 |
T1135 |
T1106 |
punct |
.,shows |
| R593 |
T1137 |
T1138 |
prep |
In,suggests |
| R594 |
T1139 |
T1137 |
pobj |
fact,In |
| R595 |
T1140 |
T1138 |
punct |
", ",suggests |
| R596 |
T1141 |
T1142 |
det |
the,loss |
| R597 |
T1142 |
T1138 |
nsubj |
loss,suggests |
| R598 |
T1143 |
T1142 |
amod |
selective,loss |
| R599 |
T1144 |
T1142 |
prep |
of,loss |
| R600 |
T1145 |
T1144 |
pobj |
vestibular,of |
| R601 |
T1146 |
T1145 |
prep |
as,vestibular |
| R602 |
T1147 |
T1146 |
prep |
compared,as |
| R603 |
T1148 |
T1147 |
prep |
to,compared |
| R604 |
T1149 |
T1148 |
pobj |
cochlear,to |
| R605 |
T1150 |
T1151 |
amod |
sensory,neurons |
| R606 |
T1151 |
T1145 |
appos |
neurons,vestibular |
| R607 |
T1152 |
T1153 |
punct |
(,% |
| R608 |
T1153 |
T1145 |
parataxis |
%,vestibular |
| R609 |
T1154 |
T1153 |
nummod |
77,% |
| R610 |
T1155 |
T1153 |
cc |
versus,% |
| R611 |
T1156 |
T1157 |
nummod |
29,% |
| R612 |
T1157 |
T1153 |
conj |
%,% |
| R613 |
T1158 |
T1153 |
punct |
;,% |
| R614 |
T1159 |
T1160 |
punct |
[,3 |
| R615 |
T1160 |
T1153 |
parataxis |
3,% |
| R616 |
T1161 |
T1160 |
punct |
],3 |
| R617 |
T1162 |
T1153 |
punct |
),% |
| R618 |
T1163 |
T1164 |
mark |
that,be |
| R619 |
T1164 |
T1138 |
ccomp |
be,suggests |
| R620 |
T1165 |
T1166 |
nmod |
NT,expression |
| R621 |
T1166 |
T1164 |
nsubj |
expression,be |
| R622 |
T1167 |
T1165 |
punct |
-,NT |
| R623 |
T1168 |
T1165 |
nummod |
3,NT |
| R624 |
T1169 |
T1164 |
aux |
may,be |
| R625 |
T1170 |
T1171 |
advmod |
less,downregulated |
| R626 |
T1171 |
T1164 |
acomp |
downregulated,be |
| R627 |
T1172 |
T1164 |
prep |
in,be |
| R628 |
T1173 |
T1174 |
nmod |
Brn3c,mutants |
| R629 |
T1174 |
T1172 |
pobj |
mutants,in |
| R630 |
T1175 |
T1174 |
amod |
null,mutants |
| R631 |
T1176 |
T1164 |
prep |
than,be |
| R632 |
T1177 |
T1176 |
pobj |
BDNF,than |
| R633 |
T1178 |
T1179 |
punct |
[,9 |
| R634 |
T1179 |
T1164 |
parataxis |
9,be |
| R635 |
T1180 |
T1179 |
nummod |
6,9 |
| R636 |
T1181 |
T1179 |
punct |
",",9 |
| R637 |
T1182 |
T1179 |
nummod |
8,9 |
| R638 |
T1183 |
T1179 |
punct |
",",9 |
| R639 |
T1184 |
T1179 |
punct |
],9 |
| R640 |
T1185 |
T1164 |
punct |
", ",be |
| R641 |
T1186 |
T1164 |
prep |
provided,be |
| R642 |
T1187 |
T1188 |
mark |
that,takes |
| R643 |
T1188 |
T1186 |
pcomp |
takes,provided |
| R644 |
T1189 |
T1190 |
advmod |
at,least |
| R645 |
T1190 |
T1191 |
advmod |
least,differentiation |
| R646 |
T1191 |
T1188 |
nsubj |
differentiation,takes |
| R647 |
T1192 |
T1191 |
det |
some,differentiation |
| R648 |
T1193 |
T1191 |
prep |
of,differentiation |
| R649 |
T1194 |
T1195 |
amod |
supporting,cells |
| R650 |
T1195 |
T1193 |
pobj |
cells,of |
| R651 |
T1196 |
T1188 |
dobj |
place,takes |
| R652 |
T1197 |
T1138 |
punct |
.,suggests |
| R653 |
T1199 |
T1200 |
prep |
In,downregulated |
| R654 |
T1201 |
T1202 |
det |
the,ear |
| R655 |
T1202 |
T1199 |
pobj |
ear,In |
| R656 |
T1203 |
T1204 |
punct |
[,4 |
| R657 |
T1204 |
T1199 |
parataxis |
4,In |
| R658 |
T1205 |
T1204 |
punct |
],4 |
| R659 |
T1206 |
T1207 |
advmod |
as,as |
| R660 |
T1207 |
T1199 |
cc |
as,In |
| R661 |
T1208 |
T1207 |
advmod |
well,as |
| R662 |
T1209 |
T1210 |
advmod |
elsewhere,10 |
| R663 |
T1210 |
T1199 |
conj |
10,In |
| R664 |
T1211 |
T1210 |
punct |
[,10 |
| R665 |
T1212 |
T1210 |
punct |
],10 |
| R666 |
T1213 |
T1200 |
nsubjpass |
neurotrophins,downregulated |
| R667 |
T1214 |
T1200 |
auxpass |
are,downregulated |
| R668 |
T1215 |
T1200 |
advmod |
progressively,downregulated |
| R669 |
T1216 |
T1200 |
prep |
in,downregulated |
| R670 |
T1217 |
T1218 |
amod |
postnatal,mammals |
| R671 |
T1218 |
T1216 |
pobj |
mammals,in |
| R672 |
T1219 |
T1200 |
cc |
and,downregulated |
| R673 |
T1220 |
T1221 |
advmod |
possibly,replaced |
| R674 |
T1221 |
T1200 |
conj |
replaced,downregulated |
| R675 |
T1222 |
T1221 |
agent |
by,replaced |
| R676 |
T1223 |
T1224 |
amod |
other,factors |
| R677 |
T1224 |
T1222 |
pobj |
factors,by |
| R678 |
T1225 |
T1226 |
punct |
[,11 |
| R679 |
T1226 |
T1221 |
parataxis |
11,replaced |
| R680 |
T1227 |
T1226 |
punct |
],11 |
| R681 |
T1228 |
T1200 |
punct |
.,downregulated |
| R682 |
T1230 |
T1231 |
nsubj |
We,investigated |
| R683 |
T1232 |
T1231 |
aux |
have,investigated |
| R684 |
T1233 |
T1231 |
prep |
in,investigated |
| R685 |
T1234 |
T1233 |
pobj |
detail,in |
| R686 |
T1235 |
T1236 |
det |
the,pattern |
| R687 |
T1236 |
T1231 |
dobj |
pattern,investigated |
| R688 |
T1237 |
T1236 |
prep |
of,pattern |
| R689 |
T1238 |
T1237 |
pobj |
innervation,of |
| R690 |
T1239 |
T1236 |
prep |
in,pattern |
| R691 |
T1240 |
T1241 |
det |
the,mutants |
| R692 |
T1241 |
T1239 |
pobj |
mutants,in |
| R693 |
T1242 |
T1241 |
compound |
Brn3c,mutants |
| R694 |
T1243 |
T1236 |
punct |
", ",pattern |
| R695 |
T1244 |
T1245 |
advmod |
as,as |
| R696 |
T1245 |
T1236 |
cc |
as,pattern |
| R697 |
T1246 |
T1245 |
advmod |
well,as |
| R698 |
T1247 |
T1248 |
det |
the,expression |
| R699 |
T1248 |
T1236 |
conj |
expression,pattern |
| R700 |
T1249 |
T1248 |
prep |
of,expression |
| R701 |
T1250 |
T1249 |
pobj |
NT,of |
| R702 |
T1251 |
T1250 |
punct |
-,NT |
| R703 |
T1252 |
T1250 |
nummod |
3,NT |
| R704 |
T1253 |
T1250 |
cc |
and,NT |
| R705 |
T1254 |
T1250 |
conj |
BDNF,NT |
| R706 |
T1255 |
T1231 |
punct |
.,investigated |
| R707 |
T1257 |
T1258 |
nsubj |
We,want |
| R708 |
T1259 |
T1260 |
aux |
to,evaluate |
| R709 |
T1260 |
T1258 |
xcomp |
evaluate,want |
| R710 |
T1261 |
T1262 |
det |
a,correlation |
| R711 |
T1262 |
T1260 |
dobj |
correlation,evaluate |
| R712 |
T1263 |
T1262 |
amod |
possible,correlation |
| R713 |
T1264 |
T1262 |
prep |
between,correlation |
| R714 |
T1265 |
T1266 |
det |
the,topology |
| R715 |
T1266 |
T1264 |
pobj |
topology,between |
| R716 |
T1267 |
T1266 |
prep |
of,topology |
| R717 |
T1268 |
T1269 |
amod |
sensory,neuron |
| R718 |
T1269 |
T1270 |
compound |
neuron,loss |
| R719 |
T1270 |
T1267 |
pobj |
loss,of |
| R720 |
T1271 |
T1266 |
cc |
and,topology |
| R721 |
T1272 |
T1266 |
conj |
absence,topology |
| R722 |
T1273 |
T1272 |
prep |
of,absence |
| R723 |
T1274 |
T1275 |
det |
a,neurotrophin |
| R724 |
T1275 |
T1273 |
pobj |
neurotrophin,of |
| R725 |
T1276 |
T1275 |
amod |
specific,neurotrophin |
| R726 |
T1277 |
T1275 |
cc |
or,neurotrophin |
| R727 |
T1278 |
T1279 |
amod |
topological,loss |
| R728 |
T1279 |
T1275 |
conj |
loss,neurotrophin |
| R729 |
T1280 |
T1279 |
prep |
of,loss |
| R730 |
T1281 |
T1282 |
compound |
hair,cells |
| R731 |
T1282 |
T1280 |
pobj |
cells,of |
| R732 |
T1283 |
T1262 |
prep |
at,correlation |
| R733 |
T1284 |
T1283 |
pobj |
birth,at |
| R734 |
T1285 |
T1283 |
cc |
and,at |
| R735 |
T1286 |
T1283 |
conj |
in,at |
| R736 |
T1287 |
T1288 |
amod |
older,animals |
| R737 |
T1288 |
T1286 |
pobj |
animals,in |
| R738 |
T1289 |
T1258 |
punct |
.,want |
| R739 |
T1291 |
T1292 |
det |
This,information |
| R740 |
T1292 |
T1293 |
nsubj |
information,be |
| R741 |
T1294 |
T1293 |
aux |
could,be |
| R742 |
T1295 |
T1293 |
acomp |
important,be |
| R743 |
T1296 |
T1295 |
prep |
for,important |
| R744 |
T1297 |
T1298 |
det |
an,evaluation |
| R745 |
T1298 |
T1296 |
pobj |
evaluation,for |
| R746 |
T1299 |
T1298 |
nmod |
in,evaluation |
| R747 |
T1300 |
T1299 |
punct |
-,in |
| R748 |
T1301 |
T1299 |
pobj |
depth,in |
| R749 |
T1302 |
T1298 |
prep |
of,evaluation |
| R750 |
T1303 |
T1304 |
det |
the,deafness |
| R751 |
T1304 |
T1302 |
pobj |
deafness,of |
| R752 |
T1305 |
T1304 |
amod |
human,deafness |
| R753 |
T1306 |
T1304 |
acl |
related,deafness |
| R754 |
T1307 |
T1306 |
prep |
to,related |
| R755 |
T1308 |
T1309 |
det |
the,gene |
| R756 |
T1309 |
T1307 |
pobj |
gene,to |
| R757 |
T1310 |
T1309 |
compound |
Pou4f3,gene |
| R758 |
T1311 |
T1309 |
punct |
", ",gene |
| R759 |
T1312 |
T1309 |
appos |
DFNA15,gene |
| R760 |
T1313 |
T1314 |
punct |
[,12 |
| R761 |
T1314 |
T1293 |
parataxis |
12,be |
| R762 |
T1315 |
T1314 |
punct |
],12 |
| R763 |
T1316 |
T1293 |
punct |
.,be |
| R764 |
T1318 |
T1319 |
nsubj |
We,report |
| R765 |
T1320 |
T1319 |
advmod |
here,report |
| R766 |
T1321 |
T1322 |
amod |
long,term |
| R767 |
T1322 |
T1323 |
compound |
term,retention |
| R768 |
T1323 |
T1319 |
dobj |
retention,report |
| R769 |
T1324 |
T1323 |
prep |
of,retention |
| R770 |
T1325 |
T1326 |
amod |
cochlear,neurons |
| R771 |
T1326 |
T1324 |
pobj |
neurons,of |
| R772 |
T1327 |
T1326 |
amod |
sensory,neurons |
| R773 |
T1328 |
T1323 |
prep |
for,retention |
| R774 |
T1329 |
T1330 |
advmod |
at,6 |
| R775 |
T1330 |
T1332 |
nummod |
6,months |
| R776 |
T1331 |
T1330 |
advmod |
least,6 |
| R777 |
T1332 |
T1328 |
pobj |
months,for |
| R778 |
T1333 |
T1323 |
punct |
", ",retention |
| R779 |
T1334 |
T1335 |
prep |
in,in |
| R780 |
T1335 |
T1323 |
prep |
in,retention |
| R781 |
T1336 |
T1334 |
amod |
particular,in |
| R782 |
T1337 |
T1338 |
det |
the,apex |
| R783 |
T1338 |
T1335 |
pobj |
apex,in |
| R784 |
T1339 |
T1338 |
amod |
cochlear,apex |
| R785 |
T1340 |
T1323 |
punct |
", ",retention |
| R786 |
T1341 |
T1323 |
prep |
in,retention |
| R787 |
T1342 |
T1343 |
npadvmod |
Brn3c,null |
| R788 |
T1343 |
T1344 |
amod |
null,mice |
| R789 |
T1344 |
T1341 |
pobj |
mice,in |
| R790 |
T1345 |
T1344 |
amod |
mutant,mice |
| R791 |
T1346 |
T1319 |
punct |
.,report |
| R792 |
T1348 |
T1349 |
det |
This,retention |
| R793 |
T1349 |
T1350 |
nsubj |
retention,is |
| R794 |
T1351 |
T1349 |
prep |
of,retention |
| R795 |
T1352 |
T1351 |
pobj |
afferents,of |
| R796 |
T1353 |
T1352 |
cc |
and,afferents |
| R797 |
T1354 |
T1352 |
conj |
efferents,afferents |
| R798 |
T1355 |
T1350 |
acomp |
unrelated,is |
| R799 |
T1356 |
T1355 |
prep |
to,unrelated |
| R800 |
T1357 |
T1358 |
compound |
hair,cell |
| R801 |
T1358 |
T1359 |
compound |
cell,differentiation |
| R802 |
T1359 |
T1356 |
pobj |
differentiation,to |
| R803 |
T1360 |
T1361 |
mark |
as,detected |
| R804 |
T1361 |
T1350 |
advcl |
detected,is |
| R805 |
T1362 |
T1363 |
neg |
not,cells |
| R806 |
T1363 |
T1361 |
nsubjpass |
cells,detected |
| R807 |
T1364 |
T1363 |
advmod |
even,cells |
| R808 |
T1365 |
T1363 |
amod |
immature,cells |
| R809 |
T1366 |
T1363 |
compound |
hair,cells |
| R810 |
T1367 |
T1361 |
aux |
can,detected |
| R811 |
T1368 |
T1361 |
auxpass |
be,detected |
| R812 |
T1369 |
T1361 |
prep |
at,detected |
| R813 |
T1370 |
T1371 |
amod |
early,stages |
| R814 |
T1371 |
T1369 |
pobj |
stages,at |
| R815 |
T1372 |
T1371 |
amod |
postnatal,stages |
| R816 |
T1373 |
T1361 |
prep |
with,detected |
| R817 |
T1374 |
T1375 |
compound |
MyoVII,immunocytochemistry |
| R818 |
T1375 |
T1373 |
pobj |
immunocytochemistry,with |
| R819 |
T1376 |
T1361 |
prep |
in,detected |
| R820 |
T1377 |
T1378 |
det |
this,part |
| R821 |
T1378 |
T1376 |
pobj |
part,in |
| R822 |
T1379 |
T1378 |
prep |
of,part |
| R823 |
T1380 |
T1381 |
det |
the,cochlea |
| R824 |
T1381 |
T1379 |
pobj |
cochlea,of |
| R825 |
T1382 |
T1350 |
punct |
.,is |
| R826 |
T1384 |
T1385 |
det |
This,retention |
| R827 |
T1385 |
T1386 |
nsubj |
retention,is |
| R828 |
T1387 |
T1385 |
prep |
of,retention |
| R829 |
T1388 |
T1389 |
amod |
apical,neurons |
| R830 |
T1389 |
T1387 |
pobj |
neurons,of |
| R831 |
T1390 |
T1389 |
amod |
spiral,neurons |
| R832 |
T1391 |
T1386 |
advmod |
also,is |
| R833 |
T1392 |
T1393 |
advmod |
largely,unrelated |
| R834 |
T1393 |
T1386 |
acomp |
unrelated,is |
| R835 |
T1394 |
T1393 |
prep |
to,unrelated |
| R836 |
T1395 |
T1394 |
pobj |
neurotrophins,to |
| R837 |
T1396 |
T1397 |
dep |
which,known |
| R838 |
T1397 |
T1395 |
relcl |
known,neurotrophins |
| R839 |
T1398 |
T1397 |
auxpass |
are,known |
| R840 |
T1399 |
T1400 |
aux |
to,reduced |
| R841 |
T1400 |
T1397 |
xcomp |
reduced,known |
| R842 |
T1401 |
T1400 |
auxpass |
be,reduced |
| R843 |
T1402 |
T1400 |
prep |
in,reduced |
| R844 |
T1403 |
T1404 |
poss |
their,expression |
| R845 |
T1404 |
T1402 |
pobj |
expression,in |
| R846 |
T1405 |
T1397 |
prep |
in,known |
| R847 |
T1406 |
T1407 |
amod |
neonatal,rodents |
| R848 |
T1407 |
T1405 |
pobj |
rodents,in |
| R849 |
T1408 |
T1409 |
punct |
[,4 |
| R850 |
T1409 |
T1386 |
parataxis |
4,is |
| R851 |
T1410 |
T1409 |
punct |
],4 |
| R852 |
T1411 |
T1386 |
punct |
.,is |