PMC:149350 / 161-512 JSONTXT

{"project":"craft-ca-core-dev","denotations":[{"id":"T44","span":{"begin":46,"end":52},"obj":"NCBITaxon:33208"},{"id":"T45","span":{"begin":102,"end":106},"obj":"SO:0000704"},{"id":"T46","span":{"begin":178,"end":182},"obj":"NCBITaxon:10088"},{"id":"T47","span":{"begin":334,"end":340},"obj":"PR:000005907"},{"id":"T48","span":{"begin":345,"end":351},"obj":"PR:000005908"}],"text":" functions of alpha-crystallin is to generate animal models where one or both of the alpha-crystallin gene products have been eliminated. In the single alpha-crystallin knockout mice, the remaining alpha-crystallin may fully or partially compensate for some of the functions of the missing protein, especially in the lens, where both alphaA and alphaB"}

{"project":"craft-sa-dev","denotations":[{"id":"T158","span":{"begin":31,"end":33},"obj":"VBZ"},{"id":"T164","span":{"begin":1,"end":10},"obj":"NNS"},{"id":"T167","span":{"begin":11,"end":13},"obj":"IN"},{"id":"T168","span":{"begin":14,"end":19},"obj":"NN"},{"id":"T169","span":{"begin":20,"end":30},"obj":"NN"},{"id":"T170","span":{"begin":19,"end":20},"obj":"HYPH"},{"id":"T171","span":{"begin":34,"end":36},"obj":"TO"},{"id":"T172","span":{"begin":37,"end":45},"obj":"VB"},{"id":"T173","span":{"begin":46,"end":52},"obj":"NN"},{"id":"T174","span":{"begin":53,"end":59},"obj":"NNS"},{"id":"T175","span":{"begin":60,"end":65},"obj":"WRB"},{"id":"T176","span":{"begin":126,"end":136},"obj":"VBN"},{"id":"T177","span":{"begin":66,"end":69},"obj":"CD"},{"id":"T178","span":{"begin":70,"end":72},"obj":"CC"},{"id":"T179","span":{"begin":73,"end":77},"obj":"DT"},{"id":"T180","span":{"begin":78,"end":80},"obj":"IN"},{"id":"T181","span":{"begin":81,"end":84},"obj":"DT"},{"id":"T182","span":{"begin":107,"end":115},"obj":"NNS"},{"id":"T183","span":{"begin":85,"end":90},"obj":"NN"},{"id":"T184","span":{"begin":91,"end":101},"obj":"NN"},{"id":"T185","span":{"begin":90,"end":91},"obj":"HYPH"},{"id":"T186","span":{"begin":102,"end":106},"obj":"NN"},{"id":"T187","span":{"begin":116,"end":120},"obj":"VBP"},{"id":"T188","span":{"begin":121,"end":125},"obj":"VBN"},{"id":"T189","span":{"begin":136,"end":137},"obj":"."},{"id":"T191","span":{"begin":138,"end":140},"obj":"IN"},{"id":"T192","span":{"begin":238,"end":248},"obj":"VB"},{"id":"T193","span":{"begin":141,"end":144},"obj":"DT"},{"id":"T194","span":{"begin":178,"end":182},"obj":"NNS"},{"id":"T195","span":{"begin":145,"end":151},"obj":"JJ"},{"id":"T196","span":{"begin":169,"end":177},"obj":"NN"},{"id":"T197","span":{"begin":152,"end":157},"obj":"NN"},{"id":"T198","span":{"begin":158,"end":168},"obj":"NN"},{"id":"T199","span":{"begin":157,"end":158},"obj":"HYPH"},{"id":"T200","span":{"begin":182,"end":184},"obj":","},{"id":"T201","span":{"begin":184,"end":187},"obj":"DT"},{"id":"T202","span":{"begin":204,"end":214},"obj":"NN"},{"id":"T203","span":{"begin":188,"end":197},"obj":"VBG"},{"id":"T204","span":{"begin":198,"end":203},"obj":"NN"},{"id":"T205","span":{"begin":203,"end":204},"obj":"HYPH"},{"id":"T206","span":{"begin":215,"end":218},"obj":"MD"},{"id":"T207","span":{"begin":219,"end":224},"obj":"RB"},{"id":"T208","span":{"begin":225,"end":227},"obj":"CC"},{"id":"T209","span":{"begin":228,"end":237},"obj":"RB"},{"id":"T210","span":{"begin":249,"end":252},"obj":"IN"},{"id":"T211","span":{"begin":253,"end":257},"obj":"DT"},{"id":"T212","span":{"begin":258,"end":260},"obj":"IN"},{"id":"T213","span":{"begin":261,"end":264},"obj":"DT"},{"id":"T214","span":{"begin":265,"end":274},"obj":"NNS"},{"id":"T215","span":{"begin":275,"end":277},"obj":"IN"},{"id":"T216","span":{"begin":278,"end":281},"obj":"DT"},{"id":"T217","span":{"begin":290,"end":297},"obj":"NN"},{"id":"T218","span":{"begin":282,"end":289},"obj":"VBG"},{"id":"T219","span":{"begin":297,"end":299},"obj":","},{"id":"T220","span":{"begin":299,"end":309},"obj":"RB"},{"id":"T221","span":{"begin":310,"end":312},"obj":"IN"},{"id":"T222","span":{"begin":313,"end":316},"obj":"DT"},{"id":"T223","span":{"begin":317,"end":321},"obj":"NN"},{"id":"T224","span":{"begin":321,"end":323},"obj":","},{"id":"T225","span":{"begin":323,"end":328},"obj":"WRB"},{"id":"T227","span":{"begin":329,"end":333},"obj":"CC"},{"id":"T228","span":{"begin":334,"end":340},"obj":"NN"},{"id":"T229","span":{"begin":341,"end":344},"obj":"CC"},{"id":"T230","span":{"begin":345,"end":351},"obj":"NN"}],"relations":[{"id":"R41","pred":"cc","subj":"T178","obj":"T177"},{"id":"R42","pred":"conj","subj":"T179","obj":"T177"},{"id":"R43","pred":"prep","subj":"T180","obj":"T177"},{"id":"R44","pred":"det","subj":"T181","obj":"T182"},{"id":"R45","pred":"pobj","subj":"T182","obj":"T180"},{"id":"R30","pred":"prep","subj":"T167","obj":"T164"},{"id":"R31","pred":"compound","subj":"T168","obj":"T169"},{"id":"R32","pred":"pobj","subj":"T169","obj":"T167"},{"id":"R33","pred":"punct","subj":"T170","obj":"T169"},{"id":"R34","pred":"aux","subj":"T171","obj":"T172"},{"id":"R35","pred":"xcomp","subj":"T172","obj":"T158"},{"id":"R36","pred":"compound","subj":"T173","obj":"T174"},{"id":"R37","pred":"dobj","subj":"T174","obj":"T172"},{"id":"R38","pred":"advmod","subj":"T175","obj":"T176"},{"id":"R39","pred":"relcl","subj":"T176","obj":"T174"},{"id":"R40","pred":"nsubjpass","subj":"T177","obj":"T176"},{"id":"R46","pred":"compound","subj":"T183","obj":"T184"},{"id":"R47","pred":"compound","subj":"T184","obj":"T182"},{"id":"R48","pred":"punct","subj":"T185","obj":"T184"},{"id":"R49","pred":"compound","subj":"T186","obj":"T182"},{"id":"R50","pred":"aux","subj":"T187","obj":"T176"},{"id":"R51","pred":"auxpass","subj":"T188","obj":"T176"},{"id":"R52","pred":"punct","subj":"T189","obj":"T158"},{"id":"R53","pred":"prep","subj":"T191","obj":"T192"},{"id":"R54","pred":"det","subj":"T193","obj":"T194"},{"id":"R55","pred":"pobj","subj":"T194","obj":"T191"},{"id":"R56","pred":"amod","subj":"T195","obj":"T196"},{"id":"R57","pred":"compound","subj":"T196","obj":"T194"},{"id":"R58","pred":"compound","subj":"T197","obj":"T198"},{"id":"R59","pred":"compound","subj":"T198","obj":"T196"},{"id":"R60","pred":"punct","subj":"T199","obj":"T198"},{"id":"R61","pred":"punct","subj":"T200","obj":"T192"},{"id":"R62","pred":"det","subj":"T201","obj":"T202"},{"id":"R63","pred":"nsubj","subj":"T202","obj":"T192"},{"id":"R64","pred":"amod","subj":"T203","obj":"T202"},{"id":"R65","pred":"compound","subj":"T204","obj":"T202"},{"id":"R66","pred":"punct","subj":"T205","obj":"T202"},{"id":"R67","pred":"aux","subj":"T206","obj":"T192"},{"id":"R68","pred":"advmod","subj":"T207","obj":"T192"},{"id":"R69","pred":"cc","subj":"T208","obj":"T207"},{"id":"R70","pred":"conj","subj":"T209","obj":"T207"},{"id":"R71","pred":"prep","subj":"T210","obj":"T192"},{"id":"R72","pred":"pobj","subj":"T211","obj":"T210"},{"id":"R73","pred":"prep","subj":"T212","obj":"T211"},{"id":"R74","pred":"det","subj":"T213","obj":"T214"},{"id":"R75","pred":"pobj","subj":"T214","obj":"T212"},{"id":"R76","pred":"prep","subj":"T215","obj":"T214"},{"id":"R77","pred":"det","subj":"T216","obj":"T217"},{"id":"R78","pred":"pobj","subj":"T217","obj":"T215"},{"id":"R79","pred":"amod","subj":"T218","obj":"T217"},{"id":"R80","pred":"punct","subj":"T219","obj":"T192"},{"id":"R81","pred":"advmod","subj":"T220","obj":"T221"},{"id":"R82","pred":"prep","subj":"T221","obj":"T192"},{"id":"R83","pred":"det","subj":"T222","obj":"T223"},{"id":"R84","pred":"pobj","subj":"T223","obj":"T221"},{"id":"R85","pred":"punct","subj":"T224","obj":"T223"},{"id":"R88","pred":"preconj","subj":"T227","obj":"T228"},{"id":"R90","pred":"cc","subj":"T229","obj":"T228"},{"id":"R91","pred":"conj","subj":"T230","obj":"T228"}],"text":" functions of alpha-crystallin is to generate animal models where one or both of the alpha-crystallin gene products have been eliminated. In the single alpha-crystallin knockout mice, the remaining alpha-crystallin may fully or partially compensate for some of the functions of the missing protein, especially in the lens, where both alphaA and alphaB"}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T89","span":{"begin":178,"end":182},"obj":"NCBITaxon:10088"},{"id":"T90","span":{"begin":198,"end":214},"obj":"PR_EXT:alpha_crystallin"},{"id":"T91","span":{"begin":290,"end":297},"obj":"CHEBI_PR_EXT:protein"},{"id":"T92","span":{"begin":317,"end":321},"obj":"UBERON_EXT:lens"},{"id":"T93","span":{"begin":334,"end":340},"obj":"PR_EXT:000005907"},{"id":"T94","span":{"begin":345,"end":351},"obj":"PR_EXT:000005908"},{"id":"T84","span":{"begin":14,"end":30},"obj":"PR_EXT:alpha_crystallin"},{"id":"T85","span":{"begin":46,"end":52},"obj":"NCBITaxon:33208"},{"id":"T86","span":{"begin":85,"end":101},"obj":"PR_EXT:alpha_crystallin"},{"id":"T87","span":{"begin":102,"end":115},"obj":"SO_EXT:gene_product"},{"id":"T88","span":{"begin":152,"end":168},"obj":"PR_EXT:alpha_crystallin"}],"text":" functions of alpha-crystallin is to generate animal models where one or both of the alpha-crystallin gene products have been eliminated. In the single alpha-crystallin knockout mice, the remaining alpha-crystallin may fully or partially compensate for some of the functions of the missing protein, especially in the lens, where both alphaA and alphaB"}