PMC:149350 / 116-731
Annnotations
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T44 | 91-97 | NCBITaxon:33208 | denotes | animal |
| T45 | 147-151 | SO:0000704 | denotes | gene |
| T46 | 223-227 | NCBITaxon:10088 | denotes | mice |
| T47 | 379-385 | PR:000005907 | denotes | alphaA |
| T48 | 390-396 | PR:000005908 | denotes | alphaB |
| T49 | 410-419 | GO:0010467 | denotes | expressed |
| T50 | 520-524 | NCBITaxon:10088 | denotes | mice |
| T51 | 529-533 | NCBITaxon:10088 | denotes | mice |
| T52 | 566-573 | _FRAGMENT | denotes | alphaA- |
| T53 | 585-595 | PR:000005907 | denotes | crystallin |
| T54 | 578-595 | PR:000005908 | denotes | alphaB-crystallin |
| T55 | 596-601 | SO:0000704 | denotes | genes |
| T56 | 603-609 | PR:000005907 | denotes | alphaA |
| R2 | T53 | T52 | _lexicallyChainedTo | crystallin,alphaA- |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T89 | 223-227 | NCBITaxon:10088 | denotes | mice |
| T90 | 243-259 | PR_EXT:alpha_crystallin | denotes | alpha-crystallin |
| T91 | 335-342 | CHEBI_PR_EXT:protein | denotes | protein |
| T92 | 362-366 | UBERON_EXT:lens | denotes | lens |
| T93 | 379-385 | PR_EXT:000005907 | denotes | alphaA |
| T94 | 390-396 | PR_EXT:000005908 | denotes | alphaB |
| T95 | 410-419 | GO:0010467 | denotes | expressed |
| T96 | 488-498 | UBERON_EXT:lens | denotes | lenticular |
| T97 | 520-524 | NCBITaxon:10088 | denotes | mice |
| T98 | 529-533 | NCBITaxon:10088 | denotes | mice |
| T99 | 566-573 | _FRAGMENT | denotes | alphaA- |
| T100 | 585-595 | PR_EXT:000005907 | denotes | crystallin |
| T101 | 578-595 | PR_EXT:000005908 | denotes | alphaB-crystallin |
| T102 | 596-601 | SO_EXT:0000704 | denotes | genes |
| T103 | 603-609 | PR_EXT:000005907 | denotes | alphaA |
| T84 | 59-75 | PR_EXT:alpha_crystallin | denotes | alpha-crystallin |
| T85 | 91-97 | NCBITaxon:33208 | denotes | animal |
| T86 | 130-146 | PR_EXT:alpha_crystallin | denotes | alpha-crystallin |
| T87 | 147-160 | SO_EXT:gene_product | denotes | gene products |
| T88 | 197-213 | PR_EXT:alpha_crystallin | denotes | alpha-crystallin |
| R5 | T100 | T99 | _lexicallyChainedTo | crystallin,alphaA- |
craft-sa-dev
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T156 | 0-3 | CD | denotes | One |
| T157 | 4-12 | NN | denotes | approach |
| T158 | 76-78 | VBZ | denotes | is |
| T159 | 13-15 | IN | denotes | to |
| T160 | 16-25 | VBG | denotes | resolving |
| T161 | 26-30 | DT | denotes | some |
| T162 | 31-33 | IN | denotes | of |
| T163 | 34-37 | DT | denotes | the |
| T164 | 46-55 | NNS | denotes | functions |
| T165 | 38-40 | FW | denotes | in |
| T166 | 41-45 | FW | denotes | vivo |
| T167 | 56-58 | IN | denotes | of |
| T168 | 59-64 | NN | denotes | alpha |
| T169 | 65-75 | NN | denotes | crystallin |
| T170 | 64-65 | HYPH | denotes | - |
| T171 | 79-81 | TO | denotes | to |
| T172 | 82-90 | VB | denotes | generate |
| T173 | 91-97 | NN | denotes | animal |
| T174 | 98-104 | NNS | denotes | models |
| T175 | 105-110 | WRB | denotes | where |
| T176 | 171-181 | VBN | denotes | eliminated |
| T177 | 111-114 | CD | denotes | one |
| T178 | 115-117 | CC | denotes | or |
| T179 | 118-122 | DT | denotes | both |
| T180 | 123-125 | IN | denotes | of |
| T181 | 126-129 | DT | denotes | the |
| T182 | 152-160 | NNS | denotes | products |
| T183 | 130-135 | NN | denotes | alpha |
| T184 | 136-146 | NN | denotes | crystallin |
| T185 | 135-136 | HYPH | denotes | - |
| T186 | 147-151 | NN | denotes | gene |
| T187 | 161-165 | VBP | denotes | have |
| T188 | 166-170 | VBN | denotes | been |
| T189 | 181-182 | . | denotes | . |
| T190 | 182-435 | sentence | denotes | In the single alpha-crystallin knockout mice, the remaining alpha-crystallin may fully or partially compensate for some of the functions of the missing protein, especially in the lens, where both alphaA and alphaB are normally expressed at high levels. |
| T191 | 183-185 | IN | denotes | In |
| T192 | 283-293 | VB | denotes | compensate |
| T193 | 186-189 | DT | denotes | the |
| T194 | 223-227 | NNS | denotes | mice |
| T195 | 190-196 | JJ | denotes | single |
| T196 | 214-222 | NN | denotes | knockout |
| T197 | 197-202 | NN | denotes | alpha |
| T198 | 203-213 | NN | denotes | crystallin |
| T199 | 202-203 | HYPH | denotes | - |
| T200 | 227-229 | , | denotes | , |
| T201 | 229-232 | DT | denotes | the |
| T202 | 249-259 | NN | denotes | crystallin |
| T203 | 233-242 | VBG | denotes | remaining |
| T204 | 243-248 | NN | denotes | alpha |
| T205 | 248-249 | HYPH | denotes | - |
| T206 | 260-263 | MD | denotes | may |
| T207 | 264-269 | RB | denotes | fully |
| T208 | 270-272 | CC | denotes | or |
| T209 | 273-282 | RB | denotes | partially |
| T210 | 294-297 | IN | denotes | for |
| T211 | 298-302 | DT | denotes | some |
| T212 | 303-305 | IN | denotes | of |
| T213 | 306-309 | DT | denotes | the |
| T214 | 310-319 | NNS | denotes | functions |
| T215 | 320-322 | IN | denotes | of |
| T216 | 323-326 | DT | denotes | the |
| T217 | 335-342 | NN | denotes | protein |
| T218 | 327-334 | VBG | denotes | missing |
| T219 | 342-344 | , | denotes | , |
| T220 | 344-354 | RB | denotes | especially |
| T221 | 355-357 | IN | denotes | in |
| T222 | 358-361 | DT | denotes | the |
| T223 | 362-366 | NN | denotes | lens |
| T224 | 366-368 | , | denotes | , |
| T225 | 368-373 | WRB | denotes | where |
| T226 | 410-419 | VBN | denotes | expressed |
| T227 | 374-378 | CC | denotes | both |
| T228 | 379-385 | NN | denotes | alphaA |
| T229 | 386-389 | CC | denotes | and |
| T230 | 390-396 | NN | denotes | alphaB |
| T231 | 397-400 | VBP | denotes | are |
| T232 | 401-409 | RB | denotes | normally |
| T233 | 420-422 | IN | denotes | at |
| T234 | 423-427 | JJ | denotes | high |
| T235 | 428-434 | NNS | denotes | levels |
| T236 | 434-435 | . | denotes | . |
| T237 | 435-615 | sentence | denotes | The purpose of this study was to characterize gross lenticular morphology in normal mice and mice with the targeted disruption of alphaA- and alphaB-crystallin genes (alphaA/BKO). |
| T238 | 436-439 | DT | denotes | The |
| T239 | 440-447 | NN | denotes | purpose |
| T240 | 462-465 | VBD | denotes | was |
| T241 | 448-450 | IN | denotes | of |
| T242 | 451-455 | DT | denotes | this |
| T243 | 456-461 | NN | denotes | study |
| T244 | 466-468 | TO | denotes | to |
| T245 | 469-481 | VB | denotes | characterize |
| T246 | 482-487 | JJ | denotes | gross |
| T247 | 499-509 | NN | denotes | morphology |
| T248 | 488-498 | JJ | denotes | lenticular |
| T249 | 510-512 | IN | denotes | in |
| T250 | 513-519 | JJ | denotes | normal |
| T251 | 520-524 | NNS | denotes | mice |
| T252 | 525-528 | CC | denotes | and |
| T253 | 529-533 | NNS | denotes | mice |
| T254 | 534-538 | IN | denotes | with |
| T255 | 539-542 | DT | denotes | the |
| T256 | 552-562 | NN | denotes | disruption |
| T257 | 543-551 | VBN | denotes | targeted |
| T258 | 563-565 | IN | denotes | of |
| T259 | 566-572 | NN | denotes | alphaA |
| T260 | 585-595 | NN | denotes | crystallin |
| T261 | 572-573 | HYPH | denotes | - |
| T262 | 574-577 | CC | denotes | and |
| T263 | 578-584 | NN | denotes | alphaB |
| T264 | 584-585 | HYPH | denotes | - |
| T265 | 596-601 | NNS | denotes | genes |
| T266 | 602-603 | -LRB- | denotes | ( |
| T267 | 603-609 | NN | denotes | alphaA |
| T268 | 610-613 | NN | denotes | BKO |
| T269 | 609-610 | HYPH | denotes | / |
| T270 | 613-614 | -RRB- | denotes | ) |
| T271 | 614-615 | . | denotes | . |
| R41 | T178 | T177 | cc | or,one |
| R42 | T179 | T177 | conj | both,one |
| R43 | T180 | T177 | prep | of,one |
| R44 | T181 | T182 | det | the,products |
| R45 | T182 | T180 | pobj | products,of |
| R20 | T156 | T157 | nummod | One,approach |
| R21 | T157 | T158 | nsubj | approach,is |
| R22 | T159 | T157 | prep | to,approach |
| R23 | T160 | T159 | pcomp | resolving,to |
| R24 | T161 | T160 | dobj | some,resolving |
| R25 | T162 | T161 | prep | of,some |
| R26 | T163 | T164 | det | the,functions |
| R27 | T164 | T162 | pobj | functions,of |
| R28 | T165 | T166 | advmod | in,vivo |
| R29 | T166 | T164 | amod | vivo,functions |
| R30 | T167 | T164 | prep | of,functions |
| R31 | T168 | T169 | compound | alpha,crystallin |
| R32 | T169 | T167 | pobj | crystallin,of |
| R33 | T170 | T169 | punct | -,crystallin |
| R34 | T171 | T172 | aux | to,generate |
| R35 | T172 | T158 | xcomp | generate,is |
| R36 | T173 | T174 | compound | animal,models |
| R37 | T174 | T172 | dobj | models,generate |
| R38 | T175 | T176 | advmod | where,eliminated |
| R39 | T176 | T174 | relcl | eliminated,models |
| R40 | T177 | T176 | nsubjpass | one,eliminated |
| R46 | T183 | T184 | compound | alpha,crystallin |
| R47 | T184 | T182 | compound | crystallin,products |
| R48 | T185 | T184 | punct | -,crystallin |
| R49 | T186 | T182 | compound | gene,products |
| R50 | T187 | T176 | aux | have,eliminated |
| R51 | T188 | T176 | auxpass | been,eliminated |
| R52 | T189 | T158 | punct | .,is |
| R53 | T191 | T192 | prep | In,compensate |
| R54 | T193 | T194 | det | the,mice |
| R55 | T194 | T191 | pobj | mice,In |
| R56 | T195 | T196 | amod | single,knockout |
| R57 | T196 | T194 | compound | knockout,mice |
| R58 | T197 | T198 | compound | alpha,crystallin |
| R59 | T198 | T196 | compound | crystallin,knockout |
| R60 | T199 | T198 | punct | -,crystallin |
| R61 | T200 | T192 | punct | ", ",compensate |
| R62 | T201 | T202 | det | the,crystallin |
| R63 | T202 | T192 | nsubj | crystallin,compensate |
| R64 | T203 | T202 | amod | remaining,crystallin |
| R65 | T204 | T202 | compound | alpha,crystallin |
| R66 | T205 | T202 | punct | -,crystallin |
| R67 | T206 | T192 | aux | may,compensate |
| R68 | T207 | T192 | advmod | fully,compensate |
| R69 | T208 | T207 | cc | or,fully |
| R70 | T209 | T207 | conj | partially,fully |
| R71 | T210 | T192 | prep | for,compensate |
| R72 | T211 | T210 | pobj | some,for |
| R73 | T212 | T211 | prep | of,some |
| R74 | T213 | T214 | det | the,functions |
| R75 | T214 | T212 | pobj | functions,of |
| R76 | T215 | T214 | prep | of,functions |
| R77 | T216 | T217 | det | the,protein |
| R78 | T217 | T215 | pobj | protein,of |
| R79 | T218 | T217 | amod | missing,protein |
| R80 | T219 | T192 | punct | ", ",compensate |
| R81 | T220 | T221 | advmod | especially,in |
| R82 | T221 | T192 | prep | in,compensate |
| R83 | T222 | T223 | det | the,lens |
| R84 | T223 | T221 | pobj | lens,in |
| R85 | T224 | T223 | punct | ", ",lens |
| R86 | T225 | T226 | advmod | where,expressed |
| R88 | T227 | T228 | preconj | both,alphaA |
| R89 | T228 | T226 | nsubjpass | alphaA,expressed |
| R90 | T229 | T228 | cc | and,alphaA |
| R91 | T230 | T228 | conj | alphaB,alphaA |
| R92 | T231 | T226 | auxpass | are,expressed |
| R93 | T232 | T226 | advmod | normally,expressed |
| R94 | T233 | T226 | prep | at,expressed |
| R95 | T234 | T235 | amod | high,levels |
| R96 | T235 | T233 | pobj | levels,at |
| R97 | T236 | T192 | punct | .,compensate |
| R98 | T238 | T239 | det | The,purpose |
| R99 | T239 | T240 | nsubj | purpose,was |
| R100 | T241 | T239 | prep | of,purpose |
| R101 | T242 | T243 | det | this,study |
| R102 | T243 | T241 | pobj | study,of |
| R103 | T244 | T245 | aux | to,characterize |
| R104 | T245 | T240 | xcomp | characterize,was |
| R105 | T246 | T247 | amod | gross,morphology |
| R106 | T247 | T245 | dobj | morphology,characterize |
| R107 | T248 | T247 | amod | lenticular,morphology |
| R108 | T249 | T245 | prep | in,characterize |
| R109 | T250 | T251 | amod | normal,mice |
| R110 | T251 | T249 | pobj | mice,in |
| R111 | T252 | T251 | cc | and,mice |
| R112 | T253 | T251 | conj | mice,mice |
| R113 | T254 | T253 | prep | with,mice |
| R114 | T255 | T256 | det | the,disruption |
| R115 | T256 | T254 | pobj | disruption,with |
| R116 | T257 | T256 | amod | targeted,disruption |
| R117 | T258 | T256 | prep | of,disruption |
| R118 | T259 | T260 | nmod | alphaA,crystallin |
| R119 | T260 | T265 | compound | crystallin,genes |
| R120 | T261 | T259 | punct | -,alphaA |
| R121 | T262 | T259 | cc | and,alphaA |
| R122 | T263 | T259 | conj | alphaB,alphaA |
| R123 | T264 | T260 | punct | -,crystallin |
| R124 | T265 | T258 | pobj | genes,of |
| R125 | T266 | T265 | punct | (,genes |
| R126 | T267 | T268 | compound | alphaA,BKO |
| R127 | T268 | T265 | parataxis | BKO,genes |
| R128 | T269 | T268 | punct | /,BKO |
| R129 | T270 | T268 | punct | ),BKO |
| R130 | T271 | T240 | punct | .,was |
| R87 | T226 | T223 | relcl | expressed,lens |