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contrast, B62M mice displayed small decreases in body weights and growth (male 9WK was significant, female 6WK and 9WK were suggestive at P \u003c 0.05) and significant decreases in NA (male P = 0.0152) and tail length (Additional File 3 and Table 2). The decrease in NA in B62M mice is surprising since the 2M donor region is entirely nested within the 2D donor region and B62D mice showed no difference in NA (Figure 2). These data indicate the presence of three QTL with the 2D unique region. Two of which are disjoined by the B62M and B62D strains and additively decrease body weight and tail length, but not NA. The third QTL, located within the B62D unique region (Region V), increases NA canceling the effects of the B62M QTL (Region IV) decreasing NA."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T6851","span":{"begin":18,"end":22},"obj":"NCBITaxon:10088"},{"id":"T6852","span":{"begin":52,"end":56},"obj":"UBERON_EXT:body"},{"id":"T6853","span":{"begin":69,"end":75},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T6854","span":{"begin":77,"end":81},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T6855","span":{"begin":103,"end":109},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6856","span":{"begin":184,"end":188},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T6857","span":{"begin":205,"end":209},"obj":"UBERON:0002415"},{"id":"T6858","span":{"begin":277,"end":281},"obj":"NCBITaxon:10088"},{"id":"T6859","span":{"begin":377,"end":381},"obj":"NCBITaxon:10088"},{"id":"T6860","span":{"begin":463,"end":466},"obj":"SO_EXT:0000771"},{"id":"T6861","span":{"begin":574,"end":578},"obj":"UBERON_EXT:body"},{"id":"T6862","span":{"begin":590,"end":594},"obj":"UBERON:0002415"},{"id":"T6863","span":{"begin":625,"end":628},"obj":"SO_EXT:0000771"},{"id":"T6864","span":{"begin":727,"end":730},"obj":"SO_EXT:0000771"}],"text":"In contrast, B62M mice displayed small decreases in body weights and growth (male 9WK was significant, female 6WK and 9WK were suggestive at P \u003c 0.05) and significant decreases in NA (male P = 0.0152) and tail length (Additional File 3 and Table 2). The decrease in NA in B62M mice is surprising since the 2M donor region is entirely nested within the 2D donor region and B62D mice showed no difference in NA (Figure 2). These data indicate the presence of three QTL with the 2D unique region. Two of which are disjoined by the B62M and B62D strains and additively decrease body weight and tail length, but not NA. The third QTL, located within the B62D unique region (Region V), increases NA canceling the effects of the B62M QTL (Region IV) decreasing NA."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T6782","span":{"begin":18,"end":22},"obj":"NCBITaxon:10088"},{"id":"T6783","span":{"begin":205,"end":209},"obj":"UBERON:0002415"},{"id":"T6784","span":{"begin":277,"end":281},"obj":"NCBITaxon:10088"},{"id":"T6785","span":{"begin":377,"end":381},"obj":"NCBITaxon:10088"},{"id":"T6786","span":{"begin":463,"end":466},"obj":"SO:0000771"},{"id":"T6787","span":{"begin":590,"end":594},"obj":"UBERON:0002415"},{"id":"T6788","span":{"begin":625,"end":628},"obj":"SO:0000771"},{"id":"T6789","span":{"begin":727,"end":730},"obj":"SO:0000771"}],"text":"In contrast, B62M mice displayed small decreases in body weights and growth (male 9WK was significant, female 6WK and 9WK were suggestive at P \u003c 0.05) and significant decreases in NA (male P = 0.0152) and tail length (Additional File 3 and Table 2). The decrease in NA in B62M mice is surprising since the 2M donor region is entirely nested within the 2D donor region and B62D mice showed no difference in NA (Figure 2). These data indicate the presence of three QTL with the 2D unique region. Two of which are disjoined by the B62M and B62D strains and additively decrease body weight and tail length, but not NA. The third QTL, located within the B62D unique region (Region V), increases NA canceling the effects of the B62M QTL (Region IV) decreasing NA."}