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PMC:1482699 / 31310-32181 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T19342 0-2 PRP denotes We
T19343 3-12 VBD denotes sequenced
T19344 13-22 NN denotes candidate
T19345 35-40 NNS denotes genes
T19346 23-25 NN denotes hg
T19347 26-34 NN denotes modifier
T19348 41-43 TO denotes to
T19349 44-54 VB denotes complement
T19350 55-58 DT denotes the
T19351 59-75 NN denotes characterization
T19352 76-78 IN denotes of
T19353 79-82 DT denotes the
T19354 89-98 NNS denotes congenics
T19355 83-88 NN denotes speed
T19356 99-101 IN denotes on
T19357 102-105 NN denotes MMU
T19358 105-106 CD denotes 2
T19359 106-108 , denotes ,
T19360 108-109 CD denotes 9
T19361 109-111 , denotes ,
T19362 111-113 CD denotes 11
T19363 114-117 CC denotes and
T19364 118-120 CD denotes 17
T19365 120-121 . denotes .
T19366 121-318 sentence denotes A limited number of studies have identified variation within CAST coding sequence; so sequencing candidates gave us the opportunity to estimate the SNP frequency in coding sequence relative to B6.
T19367 122-123 DT denotes A
T19368 132-138 NN denotes number
T19369 124-131 JJ denotes limited
T19370 155-165 VBN denotes identified
T19371 139-141 IN denotes of
T19372 142-149 NNS denotes studies
T19373 150-154 VBP denotes have
T19374 166-175 NN denotes variation
T19375 176-182 IN denotes within
T19376 183-187 NN denotes CAST
T19377 195-203 NN denotes sequence
T19378 188-194 NN denotes coding
T19379 203-204 : denotes ;
T19380 205-207 CC denotes so
T19381 208-218 VBG denotes sequencing
T19382 219-229 NNS denotes candidates
T19383 230-234 VBD denotes gave
T19384 235-237 PRP denotes us
T19385 238-241 DT denotes the
T19386 242-253 NN denotes opportunity
T19387 254-256 TO denotes to
T19388 257-265 VB denotes estimate
T19389 266-269 DT denotes the
T19390 274-283 NN denotes frequency
T19391 270-273 NN denotes SNP
T19392 284-286 IN denotes in
T19393 287-293 NN denotes coding
T19394 294-302 NN denotes sequence
T19395 303-311 JJ denotes relative
T19396 312-314 IN denotes to
T19397 315-317 NN denotes B6
T19398 317-318 . denotes .
T19399 318-426 sentence denotes This information will be vital to future fine mapping studies, which will include gene expression analysis.
T19400 319-323 DT denotes This
T19401 324-335 NN denotes information
T19402 341-343 VB denotes be
T19403 336-340 MD denotes will
T19404 344-349 JJ denotes vital
T19405 350-352 IN denotes to
T19406 353-359 JJ denotes future
T19407 373-380 NNS denotes studies
T19408 360-364 JJ denotes fine
T19409 365-372 NN denotes mapping
T19410 380-382 , denotes ,
T19411 382-387 WDT denotes which
T19412 393-400 VB denotes include
T19413 388-392 MD denotes will
T19414 401-405 NN denotes gene
T19415 406-416 NN denotes expression
T19416 417-425 NN denotes analysis
T19417 425-426 . denotes .
T19418 426-640 sentence denotes The high SNP frequency (0.312%; 295 SNP in 94.492 kbp) in CAST genes may lead to a higher rate of false positives using DNA microarrays or quantitative real-time PCR assays, most of which are based on B6 sequence.
T19419 427-430 DT denotes The
T19420 440-449 NN denotes frequency
T19421 431-435 JJ denotes high
T19422 436-439 NN denotes SNP
T19423 500-504 VB denotes lead
T19424 450-451 -LRB- denotes (
T19425 463-466 NN denotes SNP
T19426 451-456 CD denotes 0.312
T19427 456-457 NN denotes %
T19428 457-458 : denotes ;
T19429 459-462 CD denotes 295
T19430 467-469 IN denotes in
T19431 470-476 CD denotes 94.492
T19432 477-480 NN denotes kbp
T19433 480-481 -RRB- denotes )
T19434 482-484 IN denotes in
T19435 485-489 NN denotes CAST
T19436 490-495 NNS denotes genes
T19437 496-499 MD denotes may
T19438 505-507 IN denotes to
T19439 508-509 DT denotes a
T19440 517-521 NN denotes rate
T19441 510-516 JJR denotes higher
T19442 522-524 IN denotes of
T19443 525-530 JJ denotes false
T19444 531-540 NNS denotes positives
T19445 541-546 VBG denotes using
T19446 547-550 NN denotes DNA
T19447 551-562 NNS denotes microarrays
T19448 563-565 CC denotes or
T19449 566-578 JJ denotes quantitative
T19450 593-599 NNS denotes assays
T19451 579-583 JJ denotes real
T19452 584-588 NN denotes time
T19453 583-584 HYPH denotes -
T19454 589-592 NN denotes PCR
T19455 599-601 , denotes ,
T19456 601-605 JJS denotes most
T19457 619-624 VBN denotes based
T19458 606-608 IN denotes of
T19459 609-614 WDT denotes which
T19460 615-618 VBP denotes are
T19461 625-627 IN denotes on
T19462 628-630 NN denotes B6
T19463 631-639 NN denotes sequence
T19464 639-640 . denotes .
T19465 640-871 sentence denotes Therefore, these sequence data can be used to guide the development of gene expression assays to confirm differential expression for candidates and suggests that genes identified by downstream experiments should also be sequenced.
T19466 641-650 RB denotes Therefore
T19467 679-683 VBN denotes used
T19468 650-652 , denotes ,
T19469 652-657 DT denotes these
T19470 667-671 NNS denotes data
T19471 658-666 NN denotes sequence
T19472 672-675 MD denotes can
T19473 676-678 VB denotes be
T19474 684-686 TO denotes to
T19475 687-692 VB denotes guide
T19476 693-696 DT denotes the
T19477 697-708 NN denotes development
T19478 709-711 IN denotes of
T19479 712-716 NN denotes gene
T19480 717-727 NN denotes expression
T19481 728-734 NNS denotes assays
T19482 735-737 TO denotes to
T19483 738-745 VB denotes confirm
T19484 746-758 JJ denotes differential
T19485 759-769 NN denotes expression
T19486 770-773 IN denotes for
T19487 774-784 NNS denotes candidates
T19488 785-788 CC denotes and
T19489 789-797 VBZ denotes suggests
T19490 798-802 IN denotes that
T19491 861-870 VBN denotes sequenced
T19492 803-808 NNS denotes genes
T19493 809-819 VBN denotes identified
T19494 820-822 IN denotes by
T19495 823-833 JJ denotes downstream
T19496 834-845 NNS denotes experiments
T19497 846-852 MD denotes should
T19498 853-857 RB denotes also
T19499 858-860 VB denotes be
T19500 870-871 . denotes .
R5617 T19342 T19343 nsubj We,sequenced
R5619 T19344 T19345 compound candidate,genes
R5620 T19345 T19343 dobj genes,sequenced
R5622 T19346 T19347 compound hg,modifier
R5623 T19347 T19345 compound modifier,genes
R5624 T19348 T19349 aux to,complement
R5625 T19349 T19343 advcl complement,sequenced
R5627 T19350 T19351 det the,characterization
R5628 T19351 T19349 dobj characterization,complement
R5630 T19352 T19351 prep of,characterization
R5631 T19353 T19354 det the,congenics
R5632 T19354 T19352 pobj congenics,of
R5633 T19355 T19354 compound speed,congenics
R5634 T19356 T19354 prep on,congenics
R5635 T19357 T19358 nmod MMU,2
R5637 T19358 T19356 pobj 2,on
R5638 T19359 T19358 punct ", ",2
R5639 T19360 T19358 conj 9,2
R5641 T19361 T19360 punct ", ",9
R5642 T19362 T19360 conj 11,9
R5644 T19363 T19362 cc and,11
R5645 T19364 T19362 conj 17,11
R5650 T19365 T19343 punct .,sequenced
R5652 T19367 T19368 det A,number
R5653 T19368 T19370 nsubj number,identified
R5654 T19369 T19368 amod limited,number
R5656 T19371 T19368 prep of,number
R5659 T19372 T19371 pobj studies,of
R5660 T19373 T19370 aux have,identified
R5662 T19374 T19370 dobj variation,identified
R5663 T19375 T19374 prep within,variation
R5665 T19376 T19377 compound CAST,sequence
R5666 T19377 T19375 pobj sequence,within
R5667 T19378 T19377 compound coding,sequence
R5669 T19379 T19370 punct ;,identified
R5670 T19380 T19370 cc so,identified
R5672 T19381 T19382 amod sequencing,candidates
R5673 T19382 T19383 nsubj candidates,gave
R5674 T19383 T19370 conj gave,identified
R5676 T19384 T19383 dative us,gave
R5677 T19385 T19386 det the,opportunity
R5679 T19386 T19383 dobj opportunity,gave
R5680 T19387 T19388 aux to,estimate
R5682 T19388 T19386 acl estimate,opportunity
R5683 T19389 T19390 det the,frequency
R5684 T19390 T19388 dobj frequency,estimate
R5685 T19391 T19390 compound SNP,frequency
R5686 T19392 T19390 prep in,frequency
R5688 T19393 T19394 compound coding,sequence
R5689 T19394 T19392 pobj sequence,in
R5690 T19395 T19388 advcl relative,estimate
R5692 T19396 T19395 prep to,relative
R5693 T19397 T19396 pobj B6,to
R5694 T19398 T19383 punct .,gave
R5696 T19400 T19401 det This,information
R5698 T19401 T19402 nsubj information,be
R5699 T19403 T19402 aux will,be
R5701 T19404 T19402 acomp vital,be
R5702 T19405 T19404 prep to,vital
R5703 T19406 T19407 amod future,studies
R5705 T19407 T19405 pobj studies,to
R5706 T19408 T19409 amod fine,mapping
R5707 T19409 T19407 compound mapping,studies
R5708 T19410 T19407 punct ", ",studies
R5710 T19411 T19412 dep which,include
R5711 T19412 T19407 relcl include,studies
R5712 T19413 T19412 aux will,include
R5714 T19414 T19415 compound gene,expression
R5715 T19415 T19416 compound expression,analysis
R5716 T19416 T19412 dobj analysis,include
R5718 T19417 T19402 punct .,be
R5720 T19419 T19420 det The,frequency
R5721 T19420 T19423 nsubj frequency,lead
R5722 T19421 T19420 amod high,frequency
R5724 T19422 T19420 compound SNP,frequency
R5725 T19424 T19425 punct (,SNP
R5727 T19425 T19420 parataxis SNP,frequency
R5728 T19426 T19427 nummod 0.312,%
R5729 T19427 T19425 dep %,SNP
R5731 T19428 T19425 punct ;,SNP
R5732 T19429 T19425 nummod 295,SNP
R5734 T19430 T19425 prep in,SNP
R5735 T19431 T19432 nummod 94.492,kbp
R5736 T19432 T19430 pobj kbp,in
R5737 T19433 T19425 punct ),SNP
R5738 T19434 T19420 prep in,frequency
R5739 T19435 T19436 compound CAST,genes
R5741 T19436 T19434 pobj genes,in
R5742 T19437 T19423 aux may,lead
R5743 T19438 T19423 prep to,lead
R5745 T19439 T19440 det a,rate
R5746 T19440 T19438 pobj rate,to
R5747 T19441 T19440 amod higher,rate
R5748 T19442 T19440 prep of,rate
R5749 T19443 T19444 amod false,positives
R5750 T19444 T19442 pobj positives,of
R5751 T19445 T19444 acl using,positives
R5752 T19446 T19447 compound DNA,microarrays
R5753 T19447 T19445 dobj microarrays,using
R5754 T19448 T19447 cc or,microarrays
R5756 T19449 T19450 amod quantitative,assays
R5761 T19450 T19447 conj assays,microarrays
R5763 T19451 T19452 amod real,time
R5764 T19452 T19450 compound time,assays
R5765 T19453 T19452 punct -,time
R5767 T19454 T19450 compound PCR,assays
R5768 T19455 T19447 punct ", ",microarrays
R5770 T19456 T19457 dep most,based
R5771 T19457 T19447 relcl based,microarrays
R5772 T19458 T19456 prep of,most
R5773 T19459 T19458 pobj which,of
R5775 T19460 T19457 auxpass are,based
R5776 T19461 T19457 prep on,based
R5777 T19462 T19463 compound B6,sequence
R5779 T19463 T19461 pobj sequence,on
R5780 T19464 T19423 punct .,lead
R5782 T19466 T19467 advmod Therefore,used
R5784 T19468 T19467 punct ", ",used
R5785 T19469 T19470 det these,data
R5786 T19470 T19467 nsubjpass data,used
R5788 T19471 T19470 compound sequence,data
R5789 T19472 T19467 aux can,used
R5790 T19473 T19467 auxpass be,used
R5791 T19474 T19475 aux to,guide
R5792 T19475 T19467 advcl guide,used
R5793 T19476 T19477 det the,development
R5795 T19477 T19475 dobj development,guide
R5798 T19478 T19477 prep of,development
R5799 T19479 T19480 compound gene,expression
R5800 T19480 T19481 compound expression,assays
R5802 T19481 T19478 pobj assays,of
R5803 T19482 T19483 aux to,confirm
R5805 T19483 T19475 advcl confirm,guide
R5806 T19484 T19485 amod differential,expression
R5807 T19485 T19483 dobj expression,confirm
R5809 T19486 T19483 prep for,confirm
R5810 T19487 T19486 pobj candidates,for
R5812 T19488 T19467 cc and,used
R5813 T19489 T19467 conj suggests,used
R5815 T19490 T19491 mark that,sequenced
R5816 T19491 T19489 ccomp sequenced,suggests
R5817 T19492 T19491 nsubjpass genes,sequenced
R5818 T19493 T19492 acl identified,genes
R5820 T19494 T19493 prep by,identified
R5821 T19495 T19496 amod downstream,experiments
R5823 T19496 T19494 pobj experiments,by
R5824 T19497 T19491 aux should,sequenced
R5825 T19498 T19491 advmod also,sequenced
R5827 T19499 T19491 auxpass be,sequenced
R5828 T19500 T19467 punct .,used

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T17668 35-40 SO_EXT:0000704 denotes genes
T17669 166-175 SO_EXT:sequence_variation_entity_or_quality denotes variation
T17670 188-203 SO_EXT:coding_sequence denotes coding sequence
T17671 270-273 SO_EXT:0000694 denotes SNP
T17672 287-302 SO_EXT:coding_sequence denotes coding sequence
T17673 401-405 SO_EXT:0000704 denotes gene
T17674 401-416 GO:0010467 denotes gene expression
T17675 436-439 SO_EXT:0000694 denotes SNP
T17676 463-466 SO_EXT:0000694 denotes SNP
T17677 478-480 SO_EXT:0000028 denotes bp
T17678 490-495 SO_EXT:0000704 denotes genes
T17679 547-550 CHEBI_SO_EXT:DNA denotes DNA
T17680 631-639 SO_EXT:biological_sequence denotes sequence
T17681 658-666 SO_EXT:biological_sequence denotes sequence
T17682 712-716 SO_EXT:0000704 denotes gene
T17683 712-727 GO:0010467 denotes gene expression
T17684 759-769 GO:0010467 denotes expression
T17685 803-808 SO_EXT:0000704 denotes genes

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T17443 35-40 SO:0000704 denotes genes
T17444 270-273 SO:0000694 denotes SNP
T17445 401-405 SO:0000704 denotes gene
T17446 401-416 GO:0010467 denotes gene expression
T17447 436-439 SO:0000694 denotes SNP
T17448 463-466 SO:0000694 denotes SNP
T17449 478-480 SO:0000028 denotes bp
T17450 490-495 SO:0000704 denotes genes
T17451 712-716 SO:0000704 denotes gene
T17452 712-727 GO:0010467 denotes gene expression
T17453 759-769 GO:0010467 denotes expression
T17454 803-808 SO:0000704 denotes genes