PMC:1482699 / 28003-28438 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1482699","sourcedb":"PMC","sourceid":"1482699","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1482699","text":"HG1 mice displayed differences only in growth traits. Originally, Q1Ucd1 had small effects and these results illustrate the power of congenic strain analysis to isolate small effect QTL, although it is likely this QTL represents the lower boundary of detection using only 20–30 congenic mice. The most notable candidate genes located within the HG1 interval are the signal transducer and activator of transcription 1 (Stat1) and Stat4.","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T18717","span":{"begin":0,"end":3},"obj":"NN"},{"id":"T18718","span":{"begin":4,"end":8},"obj":"NNS"},{"id":"T18719","span":{"begin":9,"end":18},"obj":"VBD"},{"id":"T18720","span":{"begin":19,"end":30},"obj":"NNS"},{"id":"T18721","span":{"begin":31,"end":35},"obj":"RB"},{"id":"T18722","span":{"begin":36,"end":38},"obj":"IN"},{"id":"T18723","span":{"begin":39,"end":45},"obj":"NN"},{"id":"T18724","span":{"begin":46,"end":52},"obj":"NNS"},{"id":"T18725","span":{"begin":52,"end":53},"obj":"."},{"id":"T18726","span":{"begin":53,"end":292},"obj":"sentence"},{"id":"T18727","span":{"begin":54,"end":64},"obj":"RB"},{"id":"T18728","span":{"begin":73,"end":76},"obj":"VBD"},{"id":"T18729","span":{"begin":64,"end":66},"obj":","},{"id":"T18730","span":{"begin":66,"end":72},"obj":"NN"},{"id":"T18731","span":{"begin":77,"end":82},"obj":"JJ"},{"id":"T18732","span":{"begin":83,"end":90},"obj":"NNS"},{"id":"T18733","span":{"begin":91,"end":94},"obj":"CC"},{"id":"T18734","span":{"begin":95,"end":100},"obj":"DT"},{"id":"T18735","span":{"begin":101,"end":108},"obj":"NNS"},{"id":"T18736","span":{"begin":109,"end":119},"obj":"VBP"},{"id":"T18737","span":{"begin":120,"end":123},"obj":"DT"},{"id":"T18738","span":{"begin":124,"end":129},"obj":"NN"},{"id":"T18739","span":{"begin":130,"end":132},"obj":"IN"},{"id":"T18740","span":{"begin":133,"end":141},"obj":"JJ"},{"id":"T18741","span":{"begin":142,"end":148},"obj":"NN"},{"id":"T18742","span":{"begin":149,"end":157},"obj":"NN"},{"id":"T18743","span":{"begin":158,"end":160},"obj":"TO"},{"id":"T18744","span":{"begin":161,"end":168},"obj":"VB"},{"id":"T18745","span":{"begin":169,"end":174},"obj":"JJ"},{"id":"T18746","span":{"begin":175,"end":181},"obj":"NN"},{"id":"T18747","span":{"begin":182,"end":185},"obj":"NN"},{"id":"T18748","span":{"begin":185,"end":187},"obj":","},{"id":"T18749","span":{"begin":187,"end":195},"obj":"IN"},{"id":"T18750","span":{"begin":199,"end":201},"obj":"VBZ"},{"id":"T18751","span":{"begin":196,"end":198},"obj":"PRP"},{"id":"T18752","span":{"begin":202,"end":208},"obj":"JJ"},{"id":"T18753","span":{"begin":209,"end":213},"obj":"DT"},{"id":"T18754","span":{"begin":214,"end":217},"obj":"NN"},{"id":"T18755","span":{"begin":218,"end":228},"obj":"VBZ"},{"id":"T18756","span":{"begin":229,"end":232},"obj":"DT"},{"id":"T18757","span":{"begin":239,"end":247},"obj":"NN"},{"id":"T18758","span":{"begin":233,"end":238},"obj":"JJR"},{"id":"T18759","span":{"begin":248,"end":250},"obj":"IN"},{"id":"T18760","span":{"begin":251,"end":260},"obj":"NN"},{"id":"T18761","span":{"begin":261,"end":266},"obj":"VBG"},{"id":"T18762","span":{"begin":267,"end":271},"obj":"RB"},{"id":"T18763","span":{"begin":275,"end":277},"obj":"CD"},{"id":"T18764","span":{"begin":272,"end":274},"obj":"CD"},{"id":"T18765","span":{"begin":274,"end":275},"obj":"SYM"},{"id":"T18766","span":{"begin":287,"end":291},"obj":"NNS"},{"id":"T18767","span":{"begin":278,"end":286},"obj":"JJ"},{"id":"T18768","span":{"begin":291,"end":292},"obj":"."},{"id":"T18769","span":{"begin":292,"end":435},"obj":"sentence"},{"id":"T18770","span":{"begin":293,"end":296},"obj":"DT"},{"id":"T18771","span":{"begin":320,"end":325},"obj":"NNS"},{"id":"T18772","span":{"begin":297,"end":301},"obj":"RBS"},{"id":"T18773","span":{"begin":302,"end":309},"obj":"JJ"},{"id":"T18774","span":{"begin":310,"end":319},"obj":"NN"},{"id":"T18775","span":{"begin":358,"end":361},"obj":"VBP"},{"id":"T18776","span":{"begin":326,"end":333},"obj":"VBN"},{"id":"T18777","span":{"begin":334,"end":340},"obj":"IN"},{"id":"T18778","span":{"begin":341,"end":344},"obj":"DT"},{"id":"T18779","span":{"begin":349,"end":357},"obj":"NN"},{"id":"T18780","span":{"begin":345,"end":348},"obj":"NN"},{"id":"T18781","span":{"begin":362,"end":365},"obj":"DT"},{"id":"T18782","span":{"begin":373,"end":383},"obj":"NN"},{"id":"T18783","span":{"begin":366,"end":372},"obj":"NN"},{"id":"T18784","span":{"begin":384,"end":387},"obj":"CC"},{"id":"T18785","span":{"begin":388,"end":397},"obj":"NN"},{"id":"T18786","span":{"begin":398,"end":400},"obj":"IN"},{"id":"T18787","span":{"begin":401,"end":414},"obj":"NN"},{"id":"T18788","span":{"begin":415,"end":416},"obj":"CD"},{"id":"T18789","span":{"begin":417,"end":418},"obj":"-LRB-"},{"id":"T18790","span":{"begin":418,"end":423},"obj":"NN"},{"id":"T18791","span":{"begin":423,"end":424},"obj":"-RRB-"},{"id":"T18792","span":{"begin":425,"end":428},"obj":"CC"},{"id":"T18793","span":{"begin":429,"end":434},"obj":"NN"},{"id":"T18794","span":{"begin":434,"end":435},"obj":"."}],"relations":[{"id":"R5264","pred":"compound","subj":"T18717","obj":"T18718"},{"id":"R5266","pred":"nsubj","subj":"T18718","obj":"T18719"},{"id":"R5267","pred":"dobj","subj":"T18720","obj":"T18719"},{"id":"R5269","pred":"advmod","subj":"T18721","obj":"T18722"},{"id":"R5270","pred":"prep","subj":"T18722","obj":"T18720"},{"id":"R5271","pred":"compound","subj":"T18723","obj":"T18724"},{"id":"R5272","pred":"pobj","subj":"T18724","obj":"T18722"},{"id":"R5273","pred":"punct","subj":"T18725","obj":"T18719"},{"id":"R5275","pred":"advmod","subj":"T18727","obj":"T18728"},{"id":"R5277","pred":"punct","subj":"T18729","obj":"T18728"},{"id":"R5278","pred":"nsubj","subj":"T18730","obj":"T18728"},{"id":"R5279","pred":"amod","subj":"T18731","obj":"T18732"},{"id":"R5280","pred":"dobj","subj":"T18732","obj":"T18728"},{"id":"R5282","pred":"cc","subj":"T18733","obj":"T18728"},{"id":"R5283","pred":"det","subj":"T18734","obj":"T18735"},{"id":"R5285","pred":"nsubj","subj":"T18735","obj":"T18736"},{"id":"R5287","pred":"conj","subj":"T18736","obj":"T18728"},{"id":"R5289","pred":"det","subj":"T18737","obj":"T18738"},{"id":"R5290","pred":"dobj","subj":"T18738","obj":"T18736"},{"id":"R5291","pred":"prep","subj":"T18739","obj":"T18738"},{"id":"R5292","pred":"amod","subj":"T18740","obj":"T18741"},{"id":"R5296","pred":"compound","subj":"T18741","obj":"T18742"},{"id":"R5298","pred":"pobj","subj":"T18742","obj":"T18739"},{"id":"R5299","pred":"aux","subj":"T18743","obj":"T18744"},{"id":"R5301","pred":"acl","subj":"T18744","obj":"T18738"},{"id":"R5302","pred":"amod","subj":"T18745","obj":"T18746"},{"id":"R5307","pred":"compound","subj":"T18746","obj":"T18747"},{"id":"R5309","pred":"dobj","subj":"T18747","obj":"T18744"},{"id":"R5311","pred":"punct","subj":"T18748","obj":"T18736"},{"id":"R5312","pred":"mark","subj":"T18749","obj":"T18750"},{"id":"R5313","pred":"advcl","subj":"T18750","obj":"T18736"},{"id":"R5315","pred":"nsubj","subj":"T18751","obj":"T18750"},{"id":"R5316","pred":"acomp","subj":"T18752","obj":"T18750"},{"id":"R5318","pred":"det","subj":"T18753","obj":"T18754"},{"id":"R5319","pred":"nsubj","subj":"T18754","obj":"T18755"},{"id":"R5320","pred":"advcl","subj":"T18755","obj":"T18752"},{"id":"R5321","pred":"det","subj":"T18756","obj":"T18757"},{"id":"R5322","pred":"dobj","subj":"T18757","obj":"T18755"},{"id":"R5324","pred":"amod","subj":"T18758","obj":"T18757"},{"id":"R5325","pred":"prep","subj":"T18759","obj":"T18757"},{"id":"R5326","pred":"pobj","subj":"T18760","obj":"T18759"},{"id":"R5328","pred":"acl","subj":"T18761","obj":"T18757"},{"id":"R5329","pred":"advmod","subj":"T18762","obj":"T18763"},{"id":"R5331","pred":"nummod","subj":"T18763","obj":"T18766"},{"id":"R5332","pred":"quantmod","subj":"T18764","obj":"T18763"},{"id":"R5333","pred":"punct","subj":"T18765","obj":"T18763"},{"id":"R5335","pred":"dobj","subj":"T18766","obj":"T18761"},{"id":"R5336","pred":"amod","subj":"T18767","obj":"T18766"},{"id":"R5337","pred":"punct","subj":"T18768","obj":"T18736"},{"id":"R5339","pred":"det","subj":"T18770","obj":"T18771"},{"id":"R5340","pred":"nsubj","subj":"T18771","obj":"T18775"},{"id":"R5342","pred":"advmod","subj":"T18772","obj":"T18773"},{"id":"R5343","pred":"amod","subj":"T18773","obj":"T18771"},{"id":"R5344","pred":"compound","subj":"T18774","obj":"T18771"},{"id":"R5346","pred":"acl","subj":"T18776","obj":"T18771"},{"id":"R5348","pred":"prep","subj":"T18777","obj":"T18776"},{"id":"R5349","pred":"det","subj":"T18778","obj":"T18779"},{"id":"R5351","pred":"pobj","subj":"T18779","obj":"T18777"},{"id":"R5352","pred":"compound","subj":"T18780","obj":"T18779"},{"id":"R5354","pred":"det","subj":"T18781","obj":"T18782"},{"id":"R5355","pred":"attr","subj":"T18782","obj":"T18775"},{"id":"R5356","pred":"compound","subj":"T18783","obj":"T18782"},{"id":"R5358","pred":"cc","subj":"T18784","obj":"T18782"},{"id":"R5359","pred":"conj","subj":"T18785","obj":"T18782"},{"id":"R5361","pred":"prep","subj":"T18786","obj":"T18785"},{"id":"R5362","pred":"pobj","subj":"T18787","obj":"T18786"},{"id":"R5363","pred":"nummod","subj":"T18788","obj":"T18787"},{"id":"R5365","pred":"punct","subj":"T18789","obj":"T18787"},{"id":"R5366","pred":"appos","subj":"T18790","obj":"T18787"},{"id":"R5367","pred":"punct","subj":"T18791","obj":"T18787"},{"id":"R5369","pred":"cc","subj":"T18792","obj":"T18787"},{"id":"R5370","pred":"conj","subj":"T18793","obj":"T18787"},{"id":"R5371","pred":"punct","subj":"T18794","obj":"T18775"}],"attributes":[{"subj":"T18717","pred":"source","obj":"craft-sa-dev"},{"subj":"T18718","pred":"source","obj":"craft-sa-dev"},{"subj":"T18719","pred":"source","obj":"craft-sa-dev"},{"subj":"T18720","pred":"source","obj":"craft-sa-dev"},{"subj":"T18721","pred":"source","obj":"craft-sa-dev"},{"subj":"T18722","pred":"source","obj":"craft-sa-dev"},{"subj":"T18723","pred":"source","obj":"craft-sa-dev"},{"subj":"T18724","pred":"source","obj":"craft-sa-dev"},{"subj":"T18725","pred":"source","obj":"craft-sa-dev"},{"subj":"T18726","pred":"source","obj":"craft-sa-dev"},{"subj":"T18727","pred":"source","obj":"craft-sa-dev"},{"subj":"T18728","pred":"source","obj":"craft-sa-dev"},{"subj":"T18729","pred":"source","obj":"craft-sa-dev"},{"subj":"T18730","pred":"source","obj":"craft-sa-dev"},{"subj":"T18731","pred":"source","obj":"craft-sa-dev"},{"subj":"T18732","pred":"source","obj":"craft-sa-dev"},{"subj":"T18733","pred":"source","obj":"craft-sa-dev"},{"subj":"T18734","pred":"source","obj":"craft-sa-dev"},{"subj":"T18735","pred":"source","obj":"craft-sa-dev"},{"subj":"T18736","pred":"source","obj":"craft-sa-dev"},{"subj":"T18737","pred":"source","obj":"craft-sa-dev"},{"subj":"T18738","pred":"source","obj":"craft-sa-dev"},{"subj":"T18739","pred":"source","obj":"craft-sa-dev"},{"subj":"T18740","pred":"source","obj":"craft-sa-dev"},{"subj":"T18741","pred":"source","obj":"craft-sa-dev"},{"subj":"T18742","pred":"source","obj":"craft-sa-dev"},{"subj":"T18743","pred":"source","obj":"craft-sa-dev"},{"subj":"T18744","pred":"source","obj":"craft-sa-dev"},{"subj":"T18745","pred":"source","obj":"craft-sa-dev"},{"subj":"T18746","pred":"source","obj":"craft-sa-dev"},{"subj":"T18747","pred":"source","obj":"craft-sa-dev"},{"subj":"T18748","pred":"source","obj":"craft-sa-dev"},{"subj":"T18749","pred":"source","obj":"craft-sa-dev"},{"subj":"T18750","pred":"source","obj":"craft-sa-dev"},{"subj":"T18751","pred":"source","obj":"craft-sa-dev"},{"subj":"T18752","pred":"source","obj":"craft-sa-dev"},{"subj":"T18753","pred":"source","obj":"craft-sa-dev"},{"subj":"T18754","pred":"source","obj":"craft-sa-dev"},{"subj":"T18755","pred":"source","obj":"craft-sa-dev"},{"subj":"T18756","pred":"source","obj":"craft-sa-dev"},{"subj":"T18757","pred":"source","obj":"craft-sa-dev"},{"subj":"T18758","pred":"source","obj":"craft-sa-dev"},{"subj":"T18759","pred":"source","obj":"craft-sa-dev"},{"subj":"T18760","pred":"source","obj":"craft-sa-dev"},{"subj":"T18761","pred":"source","obj":"craft-sa-dev"},{"subj":"T18762","pred":"source","obj":"craft-sa-dev"},{"subj":"T18763","pred":"source","obj":"craft-sa-dev"},{"subj":"T18764","pred":"source","obj":"craft-sa-dev"},{"subj":"T18765","pred":"source","obj":"craft-sa-dev"},{"subj":"T18766","pred":"source","obj":"craft-sa-dev"},{"subj":"T18767","pred":"source","obj":"craft-sa-dev"},{"subj":"T18768","pred":"source","obj":"craft-sa-dev"},{"subj":"T18769","pred":"source","obj":"craft-sa-dev"},{"subj":"T18770","pred":"source","obj":"craft-sa-dev"},{"subj":"T18771","pred":"source","obj":"craft-sa-dev"},{"subj":"T18772","pred":"source","obj":"craft-sa-dev"},{"subj":"T18773","pred":"source","obj":"craft-sa-dev"},{"subj":"T18774","pred":"source","obj":"craft-sa-dev"},{"subj":"T18775","pred":"source","obj":"craft-sa-dev"},{"subj":"T18776","pred":"source","obj":"craft-sa-dev"},{"subj":"T18777","pred":"source","obj":"craft-sa-dev"},{"subj":"T18778","pred":"source","obj":"craft-sa-dev"},{"subj":"T18779","pred":"source","obj":"craft-sa-dev"},{"subj":"T18780","pred":"source","obj":"craft-sa-dev"},{"subj":"T18781","pred":"source","obj":"craft-sa-dev"},{"subj":"T18782","pred":"source","obj":"craft-sa-dev"},{"subj":"T18783","pred":"source","obj":"craft-sa-dev"},{"subj":"T18784","pred":"source","obj":"craft-sa-dev"},{"subj":"T18785","pred":"source","obj":"craft-sa-dev"},{"subj":"T18786","pred":"source","obj":"craft-sa-dev"},{"subj":"T18787","pred":"source","obj":"craft-sa-dev"},{"subj":"T18788","pred":"source","obj":"craft-sa-dev"},{"subj":"T18789","pred":"source","obj":"craft-sa-dev"},{"subj":"T18790","pred":"source","obj":"craft-sa-dev"},{"subj":"T18791","pred":"source","obj":"craft-sa-dev"},{"subj":"T18792","pred":"source","obj":"craft-sa-dev"},{"subj":"T18793","pred":"source","obj":"craft-sa-dev"},{"subj":"T18794","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T17580","span":{"begin":366,"end":383},"obj":"GO_EXT:0004871"},{"id":"T17574","span":{"begin":4,"end":8},"obj":"NCBITaxon:10088"},{"id":"T17575","span":{"begin":39,"end":45},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T17576","span":{"begin":182,"end":185},"obj":"SO_EXT:0000771"},{"id":"T17577","span":{"begin":214,"end":217},"obj":"SO_EXT:0000771"},{"id":"T17578","span":{"begin":287,"end":291},"obj":"NCBITaxon:10088"},{"id":"T17579","span":{"begin":320,"end":325},"obj":"SO_EXT:0000704"},{"id":"T17581","span":{"begin":366,"end":416},"obj":"PR_EXT:000002087"},{"id":"T17582","span":{"begin":401,"end":414},"obj":"GO_EXT:transcription"},{"id":"T17583","span":{"begin":418,"end":423},"obj":"PR_EXT:000002087"},{"id":"T17584","span":{"begin":429,"end":434},"obj":"PR_EXT:000002090"}],"attributes":[{"subj":"T17580","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17574","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17575","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17576","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17577","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17578","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17579","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17581","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17582","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17583","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T17584","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T17387","span":{"begin":4,"end":8},"obj":"NCBITaxon:10088"},{"id":"T17388","span":{"begin":182,"end":185},"obj":"SO:0000771"},{"id":"T17389","span":{"begin":214,"end":217},"obj":"SO:0000771"},{"id":"T17390","span":{"begin":287,"end":291},"obj":"NCBITaxon:10088"},{"id":"T17391","span":{"begin":320,"end":325},"obj":"SO:0000704"},{"id":"T17392","span":{"begin":366,"end":416},"obj":"PR:000002087"},{"id":"T17393","span":{"begin":418,"end":423},"obj":"PR:000002087"},{"id":"T17394","span":{"begin":429,"end":434},"obj":"PR:000002090"}],"attributes":[{"subj":"T17387","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T17388","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T17389","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T17390","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T17391","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T17392","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T17393","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T17394","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#93ecc1","default":true},{"id":"craft-ca-core-ex-dev","color":"#eca793"},{"id":"craft-ca-core-dev","color":"#9399ec"}]}]}}