Id |
Subject |
Object |
Predicate |
Lexical cue |
T2920 |
0-13 |
RB |
denotes |
Traditionally |
T2921 |
36-45 |
VBN |
denotes |
developed |
T2922 |
13-15 |
, |
denotes |
, |
T2923 |
15-23 |
JJ |
denotes |
congenic |
T2924 |
24-31 |
NNS |
denotes |
strains |
T2925 |
32-35 |
VBP |
denotes |
are |
T2926 |
46-48 |
IN |
denotes |
by |
T2927 |
49-62 |
VBG |
denotes |
introgressing |
T2928 |
63-66 |
NN |
denotes |
QTL |
T2929 |
67-74 |
NNS |
denotes |
alleles |
T2930 |
75-79 |
IN |
denotes |
from |
T2931 |
80-81 |
DT |
denotes |
a |
T2932 |
88-94 |
NN |
denotes |
strain |
T2933 |
82-87 |
NN |
denotes |
donor |
T2934 |
94-96 |
, |
denotes |
, |
T2935 |
96-101 |
WP$ |
denotes |
whose |
T2936 |
102-112 |
NNS |
denotes |
boundaries |
T2937 |
117-124 |
VBN |
denotes |
defined |
T2938 |
113-116 |
VBP |
denotes |
are |
T2939 |
125-127 |
IN |
denotes |
by |
T2940 |
128-135 |
JJ |
denotes |
genetic |
T2941 |
136-143 |
NNS |
denotes |
markers |
T2942 |
143-145 |
, |
denotes |
, |
T2943 |
145-147 |
IN |
denotes |
on |
T2944 |
148-151 |
DT |
denotes |
the |
T2945 |
160-170 |
NN |
denotes |
background |
T2946 |
152-159 |
JJ |
denotes |
genetic |
T2947 |
171-173 |
IN |
denotes |
of |
T2948 |
174-175 |
DT |
denotes |
a |
T2949 |
186-192 |
NN |
denotes |
strain |
T2950 |
176-185 |
NN |
denotes |
recipient |
T2951 |
193-196 |
IN |
denotes |
via |
T2952 |
197-199 |
CD |
denotes |
10 |
T2953 |
200-211 |
NNS |
denotes |
backcrosses |
T2954 |
212-213 |
-LRB- |
denotes |
[ |
T2955 |
213-214 |
CD |
denotes |
4 |
T2956 |
214-215 |
-RRB- |
denotes |
] |
T2957 |
215-216 |
. |
denotes |
. |
T2958 |
216-338 |
sentence |
denotes |
While technically straightforward this is a time consuming endeavor taking over three years to construct a single strain. |
T2959 |
217-222 |
IN |
denotes |
While |
T2960 |
235-250 |
JJ |
denotes |
straightforward |
T2961 |
223-234 |
RB |
denotes |
technically |
T2962 |
256-258 |
VBZ |
denotes |
is |
T2963 |
251-255 |
NN |
denotes |
this |
T2964 |
259-260 |
DT |
denotes |
a |
T2965 |
276-284 |
NN |
denotes |
endeavor |
T2966 |
261-265 |
NN |
denotes |
time |
T2967 |
266-275 |
VBG |
denotes |
consuming |
T2968 |
285-291 |
VBG |
denotes |
taking |
T2969 |
292-296 |
IN |
denotes |
over |
T2970 |
297-302 |
CD |
denotes |
three |
T2971 |
303-308 |
NNS |
denotes |
years |
T2972 |
309-311 |
TO |
denotes |
to |
T2973 |
312-321 |
VB |
denotes |
construct |
T2974 |
322-323 |
DT |
denotes |
a |
T2975 |
331-337 |
NN |
denotes |
strain |
T2976 |
324-330 |
JJ |
denotes |
single |
T2977 |
337-338 |
. |
denotes |
. |
T2978 |
338-481 |
sentence |
denotes |
The speed congenic approach is an alternative to this lengthy process and can reduce the number of required backcrosses from 10 to five [5,6]. |
T2979 |
339-342 |
DT |
denotes |
The |
T2980 |
358-366 |
NN |
denotes |
approach |
T2981 |
343-348 |
NN |
denotes |
speed |
T2982 |
349-357 |
JJ |
denotes |
congenic |
T2983 |
367-369 |
VBZ |
denotes |
is |
T2984 |
370-372 |
DT |
denotes |
an |
T2985 |
373-384 |
NN |
denotes |
alternative |
T2986 |
385-387 |
IN |
denotes |
to |
T2987 |
388-392 |
DT |
denotes |
this |
T2988 |
401-408 |
NN |
denotes |
process |
T2989 |
393-400 |
JJ |
denotes |
lengthy |
T2990 |
409-412 |
CC |
denotes |
and |
T2991 |
413-416 |
MD |
denotes |
can |
T2992 |
417-423 |
VB |
denotes |
reduce |
T2993 |
424-427 |
DT |
denotes |
the |
T2994 |
428-434 |
NN |
denotes |
number |
T2995 |
435-437 |
IN |
denotes |
of |
T2996 |
438-446 |
VBN |
denotes |
required |
T2997 |
447-458 |
NNS |
denotes |
backcrosses |
T2998 |
459-463 |
IN |
denotes |
from |
T2999 |
464-466 |
CD |
denotes |
10 |
T3000 |
467-469 |
IN |
denotes |
to |
T3001 |
470-474 |
CD |
denotes |
five |
T3002 |
475-476 |
-LRB- |
denotes |
[ |
T3003 |
478-479 |
CD |
denotes |
6 |
T3004 |
476-477 |
CD |
denotes |
5 |
T3005 |
477-478 |
, |
denotes |
, |
T3006 |
479-480 |
-RRB- |
denotes |
] |
T3007 |
480-481 |
. |
denotes |
. |
T3008 |
481-629 |
sentence |
denotes |
This strategy uses marker-assisted selection to identify male mice inheriting fewer donor alleles, than expected on average, during each backcross. |
T3009 |
482-486 |
DT |
denotes |
This |
T3010 |
487-495 |
NN |
denotes |
strategy |
T3011 |
496-500 |
VBZ |
denotes |
uses |
T3012 |
501-507 |
NN |
denotes |
marker |
T3013 |
508-516 |
VBN |
denotes |
assisted |
T3014 |
507-508 |
HYPH |
denotes |
- |
T3015 |
517-526 |
NN |
denotes |
selection |
T3016 |
527-529 |
TO |
denotes |
to |
T3017 |
530-538 |
VB |
denotes |
identify |
T3018 |
539-543 |
JJ |
denotes |
male |
T3019 |
544-548 |
NNS |
denotes |
mice |
T3020 |
549-559 |
VBG |
denotes |
inheriting |
T3021 |
560-565 |
JJR |
denotes |
fewer |
T3022 |
572-579 |
NNS |
denotes |
alleles |
T3023 |
566-571 |
NN |
denotes |
donor |
T3024 |
579-581 |
, |
denotes |
, |
T3025 |
581-585 |
IN |
denotes |
than |
T3026 |
586-594 |
VBN |
denotes |
expected |
T3027 |
595-597 |
IN |
denotes |
on |
T3028 |
598-605 |
JJ |
denotes |
average |
T3029 |
605-607 |
, |
denotes |
, |
T3030 |
607-613 |
IN |
denotes |
during |
T3031 |
614-618 |
DT |
denotes |
each |
T3032 |
619-628 |
NN |
denotes |
backcross |
T3033 |
628-629 |
. |
denotes |
. |
T3034 |
629-796 |
sentence |
denotes |
Numerous traditionally developed and speed congenics have been used to successfully isolate mouse QTL for a wide array of traits, including growth and obesity [7-13]. |
T3035 |
630-638 |
JJ |
denotes |
Numerous |
T3036 |
673-682 |
NNS |
denotes |
congenics |
T3037 |
639-652 |
RB |
denotes |
traditionally |
T3038 |
653-662 |
VBN |
denotes |
developed |
T3039 |
663-666 |
CC |
denotes |
and |
T3040 |
667-672 |
NN |
denotes |
speed |
T3041 |
693-697 |
VBN |
denotes |
used |
T3042 |
683-687 |
VBP |
denotes |
have |
T3043 |
688-692 |
VBN |
denotes |
been |
T3044 |
698-700 |
TO |
denotes |
to |
T3045 |
714-721 |
VB |
denotes |
isolate |
T3046 |
701-713 |
RB |
denotes |
successfully |
T3047 |
722-727 |
NN |
denotes |
mouse |
T3048 |
728-731 |
NN |
denotes |
QTL |
T3049 |
732-735 |
IN |
denotes |
for |
T3050 |
736-737 |
DT |
denotes |
a |
T3051 |
743-748 |
NN |
denotes |
array |
T3052 |
738-742 |
JJ |
denotes |
wide |
T3053 |
749-751 |
IN |
denotes |
of |
T3054 |
752-758 |
NNS |
denotes |
traits |
T3055 |
758-760 |
, |
denotes |
, |
T3056 |
760-769 |
VBG |
denotes |
including |
T3057 |
770-776 |
NN |
denotes |
growth |
T3058 |
777-780 |
CC |
denotes |
and |
T3059 |
781-788 |
NN |
denotes |
obesity |
T3060 |
789-790 |
-LRB- |
denotes |
[ |
T3061 |
790-791 |
CD |
denotes |
7 |
T3062 |
791-792 |
SYM |
denotes |
- |
T3063 |
792-794 |
CD |
denotes |
13 |
T3064 |
794-795 |
-RRB- |
denotes |
] |
T3065 |
795-796 |
. |
denotes |
. |
R421 |
T2920 |
T2921 |
advmod |
Traditionally,developed |
R423 |
T2922 |
T2921 |
punct |
", ",developed |
R424 |
T2923 |
T2924 |
amod |
congenic,strains |
R426 |
T2924 |
T2921 |
nsubjpass |
strains,developed |
R427 |
T2925 |
T2921 |
auxpass |
are,developed |
R429 |
T2926 |
T2921 |
prep |
by,developed |
R430 |
T2927 |
T2926 |
pcomp |
introgressing,by |
R431 |
T2928 |
T2929 |
compound |
QTL,alleles |
R432 |
T2929 |
T2927 |
dobj |
alleles,introgressing |
R434 |
T2930 |
T2929 |
prep |
from,alleles |
R435 |
T2931 |
T2932 |
det |
a,strain |
R436 |
T2932 |
T2930 |
pobj |
strain,from |
R437 |
T2933 |
T2932 |
compound |
donor,strain |
R438 |
T2934 |
T2932 |
punct |
", ",strain |
R440 |
T2935 |
T2936 |
poss |
whose,boundaries |
R441 |
T2936 |
T2937 |
dep |
boundaries,defined |
R443 |
T2937 |
T2932 |
relcl |
defined,strain |
R445 |
T2938 |
T2937 |
auxpass |
are,defined |
R446 |
T2939 |
T2937 |
agent |
by,defined |
R447 |
T2940 |
T2941 |
amod |
genetic,markers |
R449 |
T2941 |
T2939 |
pobj |
markers,by |
R450 |
T2942 |
T2927 |
punct |
", ",introgressing |
R451 |
T2943 |
T2927 |
prep |
on,introgressing |
R453 |
T2944 |
T2945 |
det |
the,background |
R454 |
T2945 |
T2943 |
pobj |
background,on |
R455 |
T2946 |
T2945 |
amod |
genetic,background |
R457 |
T2947 |
T2945 |
prep |
of,background |
R458 |
T2948 |
T2949 |
det |
a,strain |
R459 |
T2949 |
T2947 |
pobj |
strain,of |
R461 |
T2950 |
T2949 |
compound |
recipient,strain |
R462 |
T2951 |
T2927 |
prep |
via,introgressing |
R464 |
T2952 |
T2953 |
nummod |
10,backcrosses |
R465 |
T2953 |
T2951 |
pobj |
backcrosses,via |
R466 |
T2954 |
T2955 |
punct |
[,4 |
R467 |
T2955 |
T2927 |
parataxis |
4,introgressing |
R468 |
T2956 |
T2955 |
punct |
],4 |
R470 |
T2957 |
T2921 |
punct |
.,developed |
R471 |
T2959 |
T2960 |
mark |
While,straightforward |
R472 |
T2960 |
T2962 |
advcl |
straightforward,is |
R474 |
T2961 |
T2960 |
advmod |
technically,straightforward |
R475 |
T2963 |
T2962 |
nsubj |
this,is |
R477 |
T2964 |
T2965 |
det |
a,endeavor |
R478 |
T2965 |
T2962 |
attr |
endeavor,is |
R479 |
T2966 |
T2967 |
npadvmod |
time,consuming |
R481 |
T2967 |
T2965 |
amod |
consuming,endeavor |
R482 |
T2968 |
T2965 |
acl |
taking,endeavor |
R483 |
T2969 |
T2970 |
quantmod |
over,three |
R485 |
T2970 |
T2971 |
nummod |
three,years |
R486 |
T2971 |
T2968 |
dobj |
years,taking |
R487 |
T2972 |
T2973 |
aux |
to,construct |
R488 |
T2973 |
T2968 |
advcl |
construct,taking |
R489 |
T2974 |
T2975 |
det |
a,strain |
R490 |
T2975 |
T2973 |
dobj |
strain,construct |
R492 |
T2976 |
T2975 |
amod |
single,strain |
R493 |
T2977 |
T2962 |
punct |
.,is |
R495 |
T2979 |
T2980 |
det |
The,approach |
R496 |
T2980 |
T2983 |
nsubj |
approach,is |
R498 |
T2981 |
T2982 |
npadvmod |
speed,congenic |
R499 |
T2982 |
T2980 |
amod |
congenic,approach |
R500 |
T2984 |
T2985 |
det |
an,alternative |
R502 |
T2985 |
T2983 |
attr |
alternative,is |
R503 |
T2986 |
T2985 |
prep |
to,alternative |
R505 |
T2987 |
T2988 |
det |
this,process |
R506 |
T2988 |
T2986 |
pobj |
process,to |
R507 |
T2989 |
T2988 |
amod |
lengthy,process |
R509 |
T2990 |
T2983 |
cc |
and,is |
R510 |
T2991 |
T2992 |
aux |
can,reduce |
R511 |
T2992 |
T2983 |
conj |
reduce,is |
R512 |
T2993 |
T2994 |
det |
the,number |
R514 |
T2994 |
T2992 |
dobj |
number,reduce |
R515 |
T2995 |
T2994 |
prep |
of,number |
R517 |
T2996 |
T2997 |
amod |
required,backcrosses |
R518 |
T2997 |
T2995 |
pobj |
backcrosses,of |
R519 |
T2998 |
T2992 |
prep |
from,reduce |
R521 |
T2999 |
T2998 |
pobj |
10,from |
R522 |
T3000 |
T2992 |
prep |
to,reduce |
R523 |
T3001 |
T3000 |
pobj |
five,to |
R525 |
T3002 |
T3003 |
punct |
[,6 |
R526 |
T3003 |
T2992 |
parataxis |
6,reduce |
R527 |
T3004 |
T3003 |
nummod |
5,6 |
R529 |
T3005 |
T3003 |
punct |
",",6 |
R530 |
T3006 |
T3003 |
punct |
],6 |
R531 |
T3007 |
T2983 |
punct |
.,is |
R535 |
T3009 |
T3010 |
det |
This,strategy |
R537 |
T3010 |
T3011 |
nsubj |
strategy,uses |
R538 |
T3012 |
T3013 |
npadvmod |
marker,assisted |
R539 |
T3013 |
T3015 |
amod |
assisted,selection |
R540 |
T3014 |
T3013 |
punct |
-,assisted |
R541 |
T3015 |
T3011 |
dobj |
selection,uses |
R543 |
T3016 |
T3017 |
aux |
to,identify |
R544 |
T3017 |
T3011 |
advcl |
identify,uses |
R545 |
T3018 |
T3019 |
amod |
male,mice |
R547 |
T3019 |
T3017 |
dobj |
mice,identify |
R549 |
T3020 |
T3019 |
acl |
inheriting,mice |
R550 |
T3021 |
T3022 |
amod |
fewer,alleles |
R553 |
T3022 |
T3020 |
dobj |
alleles,inheriting |
R554 |
T3023 |
T3022 |
compound |
donor,alleles |
R556 |
T3024 |
T3022 |
punct |
", ",alleles |
R557 |
T3025 |
T3026 |
mark |
than,expected |
R558 |
T3026 |
T3022 |
advcl |
expected,alleles |
R560 |
T3027 |
T3020 |
prep |
on,inheriting |
R561 |
T3028 |
T3027 |
amod |
average,on |
R562 |
T3029 |
T3011 |
punct |
", ",uses |
R564 |
T3030 |
T3011 |
prep |
during,uses |
R565 |
T3031 |
T3032 |
det |
each,backcross |
R567 |
T3032 |
T3030 |
pobj |
backcross,during |
R568 |
T3033 |
T3011 |
punct |
.,uses |
R570 |
T3035 |
T3036 |
amod |
Numerous,congenics |
R571 |
T3036 |
T3041 |
nsubjpass |
congenics,used |
R572 |
T3037 |
T3038 |
advmod |
traditionally,developed |
R574 |
T3038 |
T3036 |
amod |
developed,congenics |
R575 |
T3039 |
T3038 |
cc |
and,developed |
R576 |
T3040 |
T3038 |
conj |
speed,developed |
R578 |
T3042 |
T3041 |
aux |
have,used |
R579 |
T3043 |
T3041 |
auxpass |
been,used |
R581 |
T3044 |
T3045 |
aux |
to,isolate |
R582 |
T3045 |
T3041 |
advcl |
isolate,used |
R583 |
T3046 |
T3045 |
advmod |
successfully,isolate |
R584 |
T3047 |
T3048 |
compound |
mouse,QTL |
R586 |
T3048 |
T3045 |
dobj |
QTL,isolate |
R587 |
T3049 |
T3045 |
prep |
for,isolate |
R590 |
T3051 |
T3049 |
pobj |
array,for |
R591 |
T3052 |
T3051 |
amod |
wide,array |
R596 |
T3056 |
T3051 |
prep |
including,array |
R597 |
T3057 |
T3056 |
pobj |
growth,including |
R598 |
T3058 |
T3057 |
cc |
and,growth |
R599 |
T3059 |
T3057 |
conj |
obesity,growth |
R601 |
T3060 |
T3061 |
punct |
[,7 |
R602 |
T3061 |
T3041 |
parataxis |
7,used |
R603 |
T3062 |
T3063 |
punct |
-,13 |
R605 |
T3063 |
T3061 |
prep |
13,7 |
R606 |
T3064 |
T3061 |
punct |
],7 |
R607 |
T3065 |
T3041 |
punct |
.,used |
R589 |
T3050 |
T3051 |
det |
a,array |
R592 |
T3053 |
T3051 |
prep |
of,array |
R593 |
T3054 |
T3053 |
pobj |
traits,of |
R594 |
T3055 |
T3051 |
punct |
", ",array |