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the original intercross CAST alleles near 50 cM on MMU11 were linked with a reduction in G29, carcass ash (ASH) and carcass protein (PROT) [24]. Therefore, we measured each carcass component using chemical compositional analysis in the HGC, HG11 and HG17 strains. Originally, Carp2 was dependent on the presence of hg and no significant sex effects were detected [24]. In contrast to those results, HG11 mice displayed significant differences in growth and obesity between the sexes. In general, males demonstrated a 5% increase and females a 5% decrease in all growth-related traits (Table 4). Most of these differences, however, were not significant at a critical P \u003c 0.005, although almost all were at a nominal P \u003c 0.05. Following the same trend, males displayed an increase in tail length and a small suggestive increase in NA (P = 0.06), while females displayed significant decreases in NA. In support of the sex-specific QTL effects strain by sex interactions (P \u003c 0.04) were seen for the following growth traits: 3WK, 6WK, 9WK, G26, G29 and NA (data not shown). The basis of each interaction was an increase in the males and a decrease in females."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T11003","span":{"begin":32,"end":39},"obj":"SO_EXT:0001023"},{"id":"T11004","span":{"begin":97,"end":104},"obj":"UBERON:0008979"},{"id":"T11005","span":{"begin":119,"end":126},"obj":"UBERON:0008979"},{"id":"T11006","span":{"begin":127,"end":134},"obj":"CHEBI_PR_EXT:protein"},{"id":"T11007","span":{"begin":136,"end":140},"obj":"CHEBI_PR_EXT:protein"},{"id":"T11008","span":{"begin":176,"end":183},"obj":"UBERON:0008979"},{"id":"T11009","span":{"begin":200,"end":208},"obj":"CHEBI_EXT:chemical_substance_or_polyatomic_entity"},{"id":"T11010","span":{"begin":407,"end":411},"obj":"NCBITaxon:10088"},{"id":"T11011","span":{"begin":449,"end":455},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T11012","span":{"begin":499,"end":504},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T11013","span":{"begin":536,"end":543},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T11014","span":{"begin":565,"end":571},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T11015","span":{"begin":754,"end":759},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T11016","span":{"begin":785,"end":789},"obj":"UBERON:0002415"},{"id":"T11017","span":{"begin":853,"end":860},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T11018","span":{"begin":931,"end":934},"obj":"SO_EXT:0000771"},{"id":"T11019","span":{"begin":1009,"end":1015},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T11020","span":{"begin":1126,"end":1131},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T11021","span":{"begin":1150,"end":1157},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"}],"text":"In the original intercross CAST alleles near 50 cM on MMU11 were linked with a reduction in G29, carcass ash (ASH) and carcass protein (PROT) [24]. Therefore, we measured each carcass component using chemical compositional analysis in the HGC, HG11 and HG17 strains. Originally, Carp2 was dependent on the presence of hg and no significant sex effects were detected [24]. In contrast to those results, HG11 mice displayed significant differences in growth and obesity between the sexes. In general, males demonstrated a 5% increase and females a 5% decrease in all growth-related traits (Table 4). Most of these differences, however, were not significant at a critical P \u003c 0.005, although almost all were at a nominal P \u003c 0.05. Following the same trend, males displayed an increase in tail length and a small suggestive increase in NA (P = 0.06), while females displayed significant decreases in NA. In support of the sex-specific QTL effects strain by sex interactions (P \u003c 0.04) were seen for the following growth traits: 3WK, 6WK, 9WK, G26, G29 and NA (data not shown). The basis of each interaction was an increase in the males and a decrease in females."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T10910","span":{"begin":32,"end":39},"obj":"SO:0001023"},{"id":"T10911","span":{"begin":97,"end":104},"obj":"UBERON:0008979"},{"id":"T10912","span":{"begin":119,"end":126},"obj":"UBERON:0008979"},{"id":"T10913","span":{"begin":176,"end":183},"obj":"UBERON:0008979"},{"id":"T10914","span":{"begin":407,"end":411},"obj":"NCBITaxon:10088"},{"id":"T10915","span":{"begin":785,"end":789},"obj":"UBERON:0002415"},{"id":"T10916","span":{"begin":931,"end":934},"obj":"SO:0000771"}],"text":"In the original intercross CAST alleles near 50 cM on MMU11 were linked with a reduction in G29, carcass ash (ASH) and carcass protein (PROT) [24]. Therefore, we measured each carcass component using chemical compositional analysis in the HGC, HG11 and HG17 strains. Originally, Carp2 was dependent on the presence of hg and no significant sex effects were detected [24]. In contrast to those results, HG11 mice displayed significant differences in growth and obesity between the sexes. In general, males demonstrated a 5% increase and females a 5% decrease in all growth-related traits (Table 4). Most of these differences, however, were not significant at a critical P \u003c 0.005, although almost all were at a nominal P \u003c 0.05. Following the same trend, males displayed an increase in tail length and a small suggestive increase in NA (P = 0.06), while females displayed significant decreases in NA. In support of the sex-specific QTL effects strain by sex interactions (P \u003c 0.04) were seen for the following growth traits: 3WK, 6WK, 9WK, G26, G29 and NA (data not shown). The basis of each interaction was an increase in the males and a decrease in females."}