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These differences in adiposity are likely pleiotropic effects of the growth QTL shared between these two strains. Surprisingly, HG2M mice displayed striking sex differences in adiposity. Males exhibited an increase in AI (P = 0.0256) with a decrease in BMI (P = 0.0462) and the exact opposite was seen in females (AI, P \u003c 0.0001; BMI, P = 0.0425) (Table 2). Therefore, the obesity QTL in the HG2M unique region (Region IV) is profoundly impacted by the presence of hg."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T6914","span":{"begin":11,"end":17},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T6915","span":{"begin":47,"end":50},"obj":"UBERON:0003428"},{"id":"T6916","span":{"begin":52,"end":55},"obj":"UBERON:0015143"},{"id":"T6917","span":{"begin":57,"end":60},"obj":"UBERON:0010411"},{"id":"T6918","span":{"begin":100,"end":104},"obj":"NCBITaxon:10088"},{"id":"T6919","span":{"begin":197,"end":203},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T6920","span":{"begin":204,"end":207},"obj":"SO_EXT:0000771"},{"id":"T6921","span":{"begin":261,"end":265},"obj":"NCBITaxon:10088"},{"id":"T6922","span":{"begin":315,"end":320},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T6923","span":{"begin":433,"end":440},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6924","span":{"begin":509,"end":512},"obj":"SO_EXT:0000771"}],"text":"Similar to growth traits a general decrease in GFP, MFP, RFP, TF and AI were seen in HG2P and HG2PM mice (Region II) (Table 2). These differences in adiposity are likely pleiotropic effects of the growth QTL shared between these two strains. Surprisingly, HG2M mice displayed striking sex differences in adiposity. Males exhibited an increase in AI (P = 0.0256) with a decrease in BMI (P = 0.0462) and the exact opposite was seen in females (AI, P \u003c 0.0001; BMI, P = 0.0425) (Table 2). Therefore, the obesity QTL in the HG2M unique region (Region IV) is profoundly impacted by the presence of hg."}

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