PMC:1481596 / 7876-8510 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1481596","sourcedb":"PMC","sourceid":"1481596","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1481596","text":"We developed a new method, Complex Overlap Decomposition (COD), that given a protein interaction network identifies its functional groups and constructs the Tree of Complexes representation. Our method requires that the network satisfies certain mathematical properties. We applied the COD method to several protein interaction networks, such as the TNFα/NF-κB signaling pathway and the pheromone signaling pathway. The corresponding subnetworks for all interaction networks are extracted from high throughput experimental data. Our results show that the COD method opens a new avenue for the analysis of protein interaction networks.","tracks":[]}