PMC:1481596 / 22678-23098 JSONTXT

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We used the COD method to analyze the subnetwork spanning all the paths from NIK (NFκB-inducing kinase phosphorylating IKKα and IKKβ) with at most three edges. For the purpose of the analysis, we contracted all five members of NF-κB family into one node. As the resulting protein interaction network, shown in Figure 3(a), is chordal without weak siblings, functional groups correspond to maximal cliques in the network.