PMC:1481596 / 1487-2367 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1481596","sourcedb":"PMC","sourceid":"1481596","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1481596","text":"A major challenge in systems biology is to understand the intricate network of interacting molecules. The complexity in biological systems arises not only from various individual protein molecules but also from their organization into systems with numerous interacting partners. In fact, most cellular processes are carried out by multi-protein complexes, groups of proteins that bind together to perform a specific task. Some proteins form stable complexes, such as the ribosomal complex that consists of more than 50 proteins and three RNA molecules, while other proteins form transient associations and are part of several complexes at different stages of a cellular process. A better understanding of this higher-order organization of proteins into overlapping complexes is an important step towards unveiling functional and evolutionary mechanisms behind biological networks.","tracks":[]}