PMC:1472690 / 582-998 JSONTXT

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T311","span":{"begin":332,"end":336},"obj":"Protein"},{"id":"T303","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T304","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T305","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T306","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T307","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T308","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T309","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T310","span":{"begin":222,"end":234},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T440","span":{"begin":222,"end":234},"obj":"http://www.uniprot.org/uniprot/P01579"},{"id":"T441","span":{"begin":332,"end":336},"obj":"http://www.uniprot.org/uniprot/P10145"},{"id":"T427","span":{"begin":189,"end":193},"obj":"http://www.uniprot.org/uniprot/P05231"},{"id":"T430","span":{"begin":182,"end":187},"obj":"http://www.uniprot.org/uniprot/P01584"},{"id":"T433","span":{"begin":17,"end":24},"obj":"http://www.uniprot.org/uniprot/P06886"},{"id":"T434","span":{"begin":133,"end":139},"obj":"http://www.uniprot.org/uniprot/P06886"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"GO-BP","denotations":[{"id":"T214","span":{"begin":201,"end":209},"obj":"http://purl.obolibrary.org/obo/GO_0001906"},{"id":"T215","span":{"begin":201,"end":209},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T216","span":{"begin":201,"end":209},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T217","span":{"begin":201,"end":209},"obj":"http://purl.obolibrary.org/obo/GO_0070265"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"GO-MF","denotations":[{"id":"T338","span":{"begin":379,"end":386},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T343","span":{"begin":189,"end":193},"obj":"http://purl.obolibrary.org/obo/GO_0005138"},{"id":"T350","span":{"begin":222,"end":234},"obj":"http://purl.obolibrary.org/obo/GO_0005133"},{"id":"T351","span":{"begin":332,"end":336},"obj":"http://purl.obolibrary.org/obo/GO_0005153"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"sentences","denotations":[{"id":"T192","span":{"begin":30,"end":37},"obj":"Sentence"},{"id":"T193","span":{"begin":38,"end":263},"obj":"Sentence"},{"id":"T194","span":{"begin":264,"end":351},"obj":"Sentence"},{"id":"T6","span":{"begin":30,"end":37},"obj":"Sentence"},{"id":"T7","span":{"begin":38,"end":263},"obj":"Sentence"},{"id":"T8","span":{"begin":264,"end":351},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"simple1","denotations":[{"id":"T396","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T397","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T398","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T399","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T400","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T401","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T402","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T403","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T404","span":{"begin":332,"end":336},"obj":"Protein"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"BioNLP16_DUT","denotations":[{"id":"T860","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T861","span":{"begin":49,"end":59},"obj":"Positive_regulation"},{"id":"T862","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T863","span":{"begin":379,"end":386},"obj":"Binding"},{"id":"T864","span":{"begin":300,"end":307},"obj":"Positive_regulation"},{"id":"T828","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T829","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T830","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T831","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T832","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T833","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T834","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T835","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T836","span":{"begin":332,"end":336},"obj":"Protein"}],"relations":[{"id":"R211","pred":"themeOf","subj":"T860","obj":"T862"},{"id":"R212","pred":"themeOf","subj":"T860","obj":"T862"},{"id":"R213","pred":"themeOf","subj":"T860","obj":"T862"},{"id":"R214","pred":"themeOf","subj":"T860","obj":"T862"},{"id":"R338","pred":"themeOf","subj":"T829","obj":"T860"},{"id":"R339","pred":"themeOf","subj":"T830","obj":"T860"},{"id":"R340","pred":"themeOf","subj":"T831","obj":"T860"},{"id":"R341","pred":"themeOf","subj":"T832","obj":"T861"},{"id":"R342","pred":"themeOf","subj":"T833","obj":"T861"},{"id":"R343","pred":"themeOf","subj":"T835","obj":"T860"},{"id":"R344","pred":"themeOf","subj":"T836","obj":"T864"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T486","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T487","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T488","span":{"begin":49,"end":59},"obj":"Positive_regulation"},{"id":"T489","span":{"begin":300,"end":307},"obj":"Positive_regulation"},{"id":"T490","span":{"begin":379,"end":386},"obj":"Binding"},{"id":"T454","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T455","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T456","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T457","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T458","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T459","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T460","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T461","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T462","span":{"begin":332,"end":336},"obj":"Protein"}],"relations":[{"id":"R123","pred":"themeOf","subj":"T487","obj":"T486"},{"id":"R124","pred":"themeOf","subj":"T487","obj":"T486"},{"id":"R125","pred":"themeOf","subj":"T487","obj":"T486"},{"id":"R126","pred":"themeOf","subj":"T487","obj":"T486"},{"id":"R246","pred":"themeOf","subj":"T455","obj":"T487"},{"id":"R247","pred":"themeOf","subj":"T456","obj":"T487"},{"id":"R248","pred":"themeOf","subj":"T457","obj":"T487"},{"id":"R249","pred":"themeOf","subj":"T457","obj":"T486"},{"id":"R250","pred":"themeOf","subj":"T458","obj":"T488"},{"id":"R251","pred":"themeOf","subj":"T459","obj":"T488"},{"id":"R252","pred":"themeOf","subj":"T461","obj":"T487"},{"id":"R253","pred":"themeOf","subj":"T461","obj":"T486"},{"id":"R254","pred":"themeOf","subj":"T462","obj":"T489"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"DLUT931","denotations":[{"id":"T606","span":{"begin":49,"end":59},"obj":"Positive_regulation"},{"id":"T607","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T608","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T609","span":{"begin":300,"end":307},"obj":"Positive_regulation"},{"id":"T610","span":{"begin":379,"end":386},"obj":"Binding"},{"id":"T574","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T575","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T576","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T577","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T578","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T579","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T580","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T581","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T582","span":{"begin":332,"end":336},"obj":"Protein"}],"relations":[{"id":"R146","pred":"themeOf","subj":"T610","obj":"T609"},{"id":"R142","pred":"themeOf","subj":"T607","obj":"T608"},{"id":"R143","pred":"themeOf","subj":"T607","obj":"T608"},{"id":"R144","pred":"themeOf","subj":"T607","obj":"T608"},{"id":"R145","pred":"themeOf","subj":"T607","obj":"T608"},{"id":"R298","pred":"themeOf","subj":"T575","obj":"T607"},{"id":"R299","pred":"themeOf","subj":"T576","obj":"T607"},{"id":"R300","pred":"themeOf","subj":"T577","obj":"T607"},{"id":"R301","pred":"themeOf","subj":"T579","obj":"T606"},{"id":"R302","pred":"themeOf","subj":"T581","obj":"T607"},{"id":"R303","pred":"themeOf","subj":"T582","obj":"T609"},{"id":"R304","pred":"themeOf","subj":"T582","obj":"T610"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T765","span":{"begin":110,"end":140},"obj":"Protein"},{"id":"T767","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T772","span":{"begin":329,"end":336},"obj":"Protein"},{"id":"T773","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T778","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T789","span":{"begin":222,"end":262},"obj":"Protein"},{"id":"T790","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T798","span":{"begin":264,"end":270},"obj":"Entity"},{"id":"T800","span":{"begin":126,"end":129},"obj":"Entity"},{"id":"T812","span":{"begin":222,"end":262},"obj":"Gene_expression"},{"id":"T813","span":{"begin":222,"end":262},"obj":"Positive_regulation"},{"id":"T730","span":{"begin":264,"end":299},"obj":"Entity"},{"id":"T731","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T739","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T743","span":{"begin":271,"end":288},"obj":"Entity"},{"id":"T749","span":{"begin":243,"end":262},"obj":"Entity"},{"id":"T750","span":{"begin":349,"end":350},"obj":"Entity"},{"id":"T753","span":{"begin":246,"end":252},"obj":"Entity"},{"id":"T754","span":{"begin":387,"end":394},"obj":"Protein"},{"id":"T817","span":{"begin":141,"end":262},"obj":"Gene_expression"},{"id":"T816","span":{"begin":141,"end":262},"obj":"Gene_expression"},{"id":"T818","span":{"begin":141,"end":262},"obj":"Gene_expression"},{"id":"T819","span":{"begin":141,"end":262},"obj":"Gene_expression"}],"relations":[{"id":"R198","pred":"themeOf","subj":"T773","obj":"T819"},{"id":"R200","pred":"themeOf","subj":"T789","obj":"T812"},{"id":"R201","pred":"themeOf","subj":"T789","obj":"T813"},{"id":"R202","pred":"themeOf","subj":"T789","obj":"T818"},{"id":"R328","pred":"themeOf","subj":"T731","obj":"T816"},{"id":"R330","pred":"themeOf","subj":"T739","obj":"T817"},{"id":"R332","pred":"causeOf","subj":"T749","obj":"T813"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T514","span":{"begin":63,"end":84},"obj":"Protein"},{"id":"T518","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T519","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T520","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T521","span":{"begin":49,"end":59},"obj":"Positive_regulation"},{"id":"T522","span":{"begin":49,"end":59},"obj":"Positive_regulation"},{"id":"T523","span":{"begin":49,"end":59},"obj":"Positive_regulation"},{"id":"T515","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T516","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T517","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T524","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T525","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T526","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T527","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T528","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T529","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T530","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T531","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T532","span":{"begin":332,"end":336},"obj":"Protein"},{"id":"T533","span":{"begin":390,"end":394},"obj":"Protein"},{"id":"T535","span":{"begin":322,"end":328},"obj":"Gene_expression"},{"id":"T536","span":{"begin":379,"end":386},"obj":"Binding"},{"id":"T537","span":{"begin":379,"end":386},"obj":"Binding"},{"id":"T538","span":{"begin":300,"end":307},"obj":"Positive_regulation"}],"relations":[{"id":"R263","pred":"themeOf","subj":"T514","obj":"T521"},{"id":"R264","pred":"themeOf","subj":"T515","obj":"T522"},{"id":"R265","pred":"themeOf","subj":"T516","obj":"T523"},{"id":"R266","pred":"themeOf","subj":"T517","obj":"T524"},{"id":"R267","pred":"themeOf","subj":"T518","obj":"T525"},{"id":"R268","pred":"themeOf","subj":"T519","obj":"T526"},{"id":"R269","pred":"themeOf","subj":"T520","obj":"T527"},{"id":"R270","pred":"themeOf","subj":"T524","obj":"T528"},{"id":"R271","pred":"themeOf","subj":"T525","obj":"T529"},{"id":"R272","pred":"themeOf","subj":"T526","obj":"T530"},{"id":"R273","pred":"themeOf","subj":"T527","obj":"T531"},{"id":"R274","pred":"themeOf","subj":"T532","obj":"T535"},{"id":"R275","pred":"themeOf","subj":"T532","obj":"T536"},{"id":"R276","pred":"themeOf","subj":"T533","obj":"T536"},{"id":"R277","pred":"themeOf","subj":"T533","obj":"T537"},{"id":"R279","pred":"themeOf","subj":"T535","obj":"T538"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"testone","denotations":[{"id":"T39","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T40","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T41","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T42","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T43","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T44","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T45","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T46","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T47","span":{"begin":332,"end":336},"obj":"Protein"},{"id":"T71","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T72","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T73","span":{"begin":300,"end":307},"obj":"Positive_regulation"},{"id":"T74","span":{"begin":379,"end":386},"obj":"Binding"}],"relations":[{"id":"R2","pred":"themeOf","subj":"T43","obj":"T71"},{"id":"R3","pred":"themeOf","subj":"T44","obj":"T71"},{"id":"R5","pred":"themeOf","subj":"T46","obj":"T71"},{"id":"R22","pred":"themeOf","subj":"T71","obj":"T72"},{"id":"R4","pred":"themeOf","subj":"T45","obj":"T71"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}

{"project":"test3","denotations":[{"id":"T100","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T101","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T102","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T103","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T104","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T105","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T106","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T107","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T108","span":{"begin":332,"end":336},"obj":"Protein"},{"id":"T136","span":{"begin":20,"end":26},"obj":"Protein"},{"id":"T137","span":{"begin":49,"end":59},"obj":"Positive_regulation"},{"id":"T138","span":{"begin":86,"end":105},"obj":"Protein"},{"id":"T139","span":{"begin":110,"end":114},"obj":"Protein"},{"id":"T140","span":{"begin":133,"end":139},"obj":"Protein"},{"id":"T141","span":{"begin":168,"end":178},"obj":"Gene_expression"},{"id":"T142","span":{"begin":182,"end":187},"obj":"Protein"},{"id":"T143","span":{"begin":189,"end":193},"obj":"Protein"},{"id":"T144","span":{"begin":195,"end":218},"obj":"Protein"},{"id":"T145","span":{"begin":222,"end":234},"obj":"Protein"},{"id":"T146","span":{"begin":235,"end":242},"obj":"Positive_regulation"},{"id":"T147","span":{"begin":300,"end":307},"obj":"Positive_regulation"},{"id":"T148","span":{"begin":332,"end":336},"obj":"Protein"},{"id":"T149","span":{"begin":379,"end":386},"obj":"Binding"}],"relations":[{"id":"R42","pred":"themeOf","subj":"T138","obj":"T137"},{"id":"R43","pred":"themeOf","subj":"T139","obj":"T137"},{"id":"R44","pred":"themeOf","subj":"T140","obj":"T137"},{"id":"R45","pred":"themeOf","subj":"T141","obj":"T146"},{"id":"R46","pred":"themeOf","subj":"T142","obj":"T141"},{"id":"R47","pred":"themeOf","subj":"T143","obj":"T141"},{"id":"R48","pred":"themeOf","subj":"T144","obj":"T141"},{"id":"R49","pred":"themeOf","subj":"T145","obj":"T141"},{"id":"R50","pred":"themeOf","subj":"T148","obj":"T149"},{"id":"R51","pred":"themeOf","subj":"T148","obj":"T147"}],"text":"k syndrome toxin 1 (TSST-1).\n\nResults\nDespite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site i"}