PMC:1472690 / 166-2255
Annnotations
bionlp-st-ge-2016-test-proteins
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T311 | 748-752 | Protein | denotes | IL-8 |
| T312 | 838-842 | Protein | denotes | IL-8 |
| T313 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T314 | 892-894 | Protein | denotes | RA |
| T315 | 996-1000 | Protein | denotes | IL-8 |
| T316 | 1108-1114 | Protein | denotes | IL-1RA |
| T317 | 1219-1225 | Protein | denotes | TSST-1 |
| T318 | 1311-1317 | Protein | denotes | TSST-1 |
| T319 | 1347-1353 | Protein | denotes | NFIL-6 |
| T320 | 1358-1362 | Protein | denotes | NFAT |
| T321 | 1401-1407 | Protein | denotes | IL-1RA |
| T322 | 1449-1455 | Protein | denotes | TSST-1 |
| T323 | 1503-1508 | Protein | denotes | IL-1β |
| T324 | 1513-1517 | Protein | denotes | IL-6 |
| T325 | 1566-1572 | Protein | denotes | TSST-1 |
| T326 | 1581-1586 | Protein | denotes | IL-1β |
| T327 | 1587-1593 | Protein | denotes | IL-1RA |
| T328 | 1685-1691 | Protein | denotes | TSST-1 |
| T329 | 1701-1705 | Protein | denotes | IL-1 |
| T330 | 1730-1734 | Protein | denotes | IL-2 |
| T331 | 1936-1942 | Protein | denotes | IL-1RA |
| T332 | 2033-2039 | Protein | denotes | IL-1RA |
| T302 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T303 | 436-442 | Protein | denotes | TSST-1 |
| T304 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T305 | 526-530 | Protein | denotes | NFAT |
| T306 | 549-555 | Protein | denotes | TSST-1 |
| T307 | 598-603 | Protein | denotes | IL-1β |
| T308 | 605-609 | Protein | denotes | IL-6 |
| T309 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T310 | 638-650 | Protein | denotes | interferon γ |
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T438 | 1566-1572 | http://www.uniprot.org/uniprot/P06886 | denotes | TSST-1 |
| T439 | 1685-1691 | http://www.uniprot.org/uniprot/P06886 | denotes | TSST-1 |
| T440 | 638-650 | http://www.uniprot.org/uniprot/P01579 | denotes | interferon γ |
| T441 | 748-752 | http://www.uniprot.org/uniprot/P10145 | denotes | IL-8 |
| T442 | 838-842 | http://www.uniprot.org/uniprot/P10145 | denotes | IL-8 |
| T443 | 996-1000 | http://www.uniprot.org/uniprot/P10145 | denotes | IL-8 |
| T444 | 1108-1114 | http://www.uniprot.org/uniprot/P18510 | denotes | IL-1RA |
| T445 | 1401-1407 | http://www.uniprot.org/uniprot/P18510 | denotes | IL-1RA |
| T446 | 1587-1593 | http://www.uniprot.org/uniprot/P18510 | denotes | IL-1RA |
| T447 | 1936-1942 | http://www.uniprot.org/uniprot/P18510 | denotes | IL-1RA |
| T448 | 2033-2039 | http://www.uniprot.org/uniprot/P18510 | denotes | IL-1RA |
| T449 | 1730-1734 | http://www.uniprot.org/uniprot/P60568 | denotes | IL-2 |
| T427 | 605-609 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T428 | 1513-1517 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T430 | 598-603 | http://www.uniprot.org/uniprot/P01584 | denotes | IL-1β |
| T431 | 1503-1508 | http://www.uniprot.org/uniprot/P01584 | denotes | IL-1β |
| T432 | 1581-1586 | http://www.uniprot.org/uniprot/P01584 | denotes | IL-1β |
| T433 | 433-440 | http://www.uniprot.org/uniprot/P06886 | denotes | 1 (TSST |
| T434 | 549-555 | http://www.uniprot.org/uniprot/P06886 | denotes | TSST-1 |
| T435 | 1219-1225 | http://www.uniprot.org/uniprot/P06886 | denotes | TSST-1 |
| T436 | 1311-1317 | http://www.uniprot.org/uniprot/P06886 | denotes | TSST-1 |
| T437 | 1449-1455 | http://www.uniprot.org/uniprot/P06886 | denotes | TSST-1 |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T187 | 280-285 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T207 | 240-248 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
| T208 | 286-307 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | immune cells mediated |
| T209 | 286-307 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | immune cells mediated |
| T210 | 286-307 | http://purl.obolibrary.org/obo/GO_0019724 | denotes | immune cells mediated |
| T211 | 286-307 | http://purl.obolibrary.org/obo/GO_0002228 | denotes | immune cells mediated |
| T212 | 286-307 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | immune cells mediated |
| T213 | 286-307 | http://purl.obolibrary.org/obo/GO_0001909 | denotes | immune cells mediated |
| T214 | 617-625 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
| T215 | 617-625 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
| T216 | 617-625 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
| T217 | 617-625 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
| T218 | 1464-1485 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
| T219 | 1823-1845 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory responses |
| T220 | 1716-1734 | http://purl.obolibrary.org/obo/GO_0032623 | denotes | production of IL-2 |
| T221 | 1716-1734 | http://purl.obolibrary.org/obo/GO_0032663 | denotes | production of IL-2 |
| T222 | 1882-1891 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T223 | 2015-2025 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T336 | 1326-1337 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA binding |
| T338 | 795-802 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T339 | 1046-1053 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T340 | 1330-1337 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T341 | 1870-1877 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T343 | 605-609 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T344 | 1513-1517 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T346 | 1701-1705 | http://purl.obolibrary.org/obo/GO_0005149 | denotes | IL-1 |
| T348 | 320-334 | http://purl.obolibrary.org/obo/GO_0001872 | denotes | β-1→3-D-glucan |
| T349 | 2074-2088 | http://purl.obolibrary.org/obo/GO_0001872 | denotes | β-1→3-D-glucan |
| T350 | 638-650 | http://purl.obolibrary.org/obo/GO_0005133 | denotes | interferon γ |
| T351 | 748-752 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
| T352 | 838-842 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
| T353 | 996-1000 | http://purl.obolibrary.org/obo/GO_0005153 | denotes | IL-8 |
| T354 | 1730-1734 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | IL-2 |
| T355 | 1861-1877 | http://purl.obolibrary.org/obo/GO_0005102 | denotes | receptor binding |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T356 | 293-298 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T357 | 963-968 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T189 | 0-10 | Sentence | denotes | Background |
| T190 | 11-121 | Sentence | denotes | β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses. |
| T191 | 122-444 | Sentence | denotes | Employing a comprehensive methodological approach, the aim of our in vitro study was to elucidate novel molecular and cellular mechanisms of human peripheral blood immune cells mediated by a fungal β-1→3-D-glucan, i.e. glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1). |
| T192 | 446-453 | Sentence | denotes | Results |
| T193 | 454-679 | Sentence | denotes | Despite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. |
| T194 | 680-767 | Sentence | denotes | Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: |
| T195 | 768-852 | Sentence | denotes | 5000 pg/ml), likely due to binding of NFκB to a consensus site in the IL-8 promoter. |
| T196 | 853-921 | Sentence | denotes | An increase in IL-1receptor antagonist(RA) production (peak at 24 h: |
| T197 | 922-1008 | Sentence | denotes | 12000 pg/ml) by glucan phosphate-treated cells positively correlated with IL-8 levels. |
| T198 | 1009-1171 | Sentence | denotes | Glucan phosphate induced significant binding to a known NFIL-6 site and a new NFAT site within the IL-1RA promoter, which was confirmed by inhibition experiments. |
| T199 | 1172-1408 | Sentence | denotes | When applied in combination with either LPS or TSST-1 at the same time points, we detected that glucan phosphate elevated the LPS- and the TSST-1-induced DNA binding of NFκB, NFIL-6 and NFAT, leading to a synergistic increase of IL-1RA. |
| T200 | 1409-1518 | Sentence | denotes | Further, glucan phosphate modulated the TSST-1-induced inflammatory response via reduction of IL-1β and IL-6. |
| T201 | 1519-1639 | Sentence | denotes | As a consequence, glucan phosphate shifted the TSST-1-induced IL-1β/IL-1RA ratio towards an anti-inflammatory phenotype. |
| T202 | 1640-1735 | Sentence | denotes | Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2. |
| T203 | 1737-1747 | Sentence | denotes | Conclusion |
| T204 | 1748-1961 | Sentence | denotes | Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. |
| T205 | 1962-2089 | Sentence | denotes | Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan. |
| T3 | 0-10 | Sentence | denotes | Background |
| T4 | 11-121 | Sentence | denotes | β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses. |
| T5 | 122-444 | Sentence | denotes | Employing a comprehensive methodological approach, the aim of our in vitro study was to elucidate novel molecular and cellular mechanisms of human peripheral blood immune cells mediated by a fungal β-1→3-D-glucan, i.e. glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1). |
| T6 | 446-453 | Sentence | denotes | Results |
| T7 | 454-679 | Sentence | denotes | Despite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. |
| T8 | 680-767 | Sentence | denotes | Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: |
| T9 | 768-852 | Sentence | denotes | 5000 pg/ml), likely due to binding of NFκB to a consensus site in the IL-8 promoter. |
| T10 | 853-921 | Sentence | denotes | An increase in IL-1receptor antagonist(RA) production (peak at 24 h: |
| T11 | 922-1008 | Sentence | denotes | 12000 pg/ml) by glucan phosphate-treated cells positively correlated with IL-8 levels. |
| T12 | 1009-1171 | Sentence | denotes | Glucan phosphate induced significant binding to a known NFIL-6 site and a new NFAT site within the IL-1RA promoter, which was confirmed by inhibition experiments. |
| T13 | 1172-1408 | Sentence | denotes | When applied in combination with either LPS or TSST-1 at the same time points, we detected that glucan phosphate elevated the LPS- and the TSST-1-induced DNA binding of NFκB, NFIL-6 and NFAT, leading to a synergistic increase of IL-1RA. |
| T14 | 1409-1518 | Sentence | denotes | Further, glucan phosphate modulated the TSST-1-induced inflammatory response via reduction of IL-1β and IL-6. |
| T15 | 1519-1639 | Sentence | denotes | As a consequence, glucan phosphate shifted the TSST-1-induced IL-1β/IL-1RA ratio towards an anti-inflammatory phenotype. |
| T16 | 1640-1735 | Sentence | denotes | Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2. |
| T17 | 1737-1747 | Sentence | denotes | Conclusion |
| T18 | 1748-1961 | Sentence | denotes | Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. |
| T19 | 1962-2089 | Sentence | denotes | Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan. |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T333 | 406-426 | http://purl.bioontology.org/ontology/ICD10/A48.3 | denotes | toxic shock syndrome |
| T334 | 412-417 | http://purl.bioontology.org/ontology/ICD10/R57.9 | denotes | shock |
simple1
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T395 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T396 | 436-442 | Protein | denotes | TSST-1 |
| T397 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T398 | 526-530 | Protein | denotes | NFAT |
| T399 | 549-555 | Protein | denotes | TSST-1 |
| T400 | 598-603 | Protein | denotes | IL-1β |
| T401 | 605-609 | Protein | denotes | IL-6 |
| T402 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T403 | 638-650 | Protein | denotes | interferon γ |
| T404 | 748-752 | Protein | denotes | IL-8 |
| T405 | 838-842 | Protein | denotes | IL-8 |
| T406 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T407 | 892-894 | Protein | denotes | RA |
| T408 | 996-1000 | Protein | denotes | IL-8 |
| T409 | 1108-1114 | Protein | denotes | IL-1RA |
| T410 | 1219-1225 | Protein | denotes | TSST-1 |
| T411 | 1311-1317 | Protein | denotes | TSST-1 |
| T412 | 1347-1353 | Protein | denotes | NFIL-6 |
| T413 | 1358-1362 | Protein | denotes | NFAT |
| T414 | 1401-1407 | Protein | denotes | IL-1RA |
| T415 | 1449-1455 | Protein | denotes | TSST-1 |
| T416 | 1503-1508 | Protein | denotes | IL-1β |
| T417 | 1513-1517 | Protein | denotes | IL-6 |
| T418 | 1566-1572 | Protein | denotes | TSST-1 |
| T419 | 1581-1586 | Protein | denotes | IL-1β |
| T420 | 1587-1593 | Protein | denotes | IL-1RA |
| T421 | 1685-1691 | Protein | denotes | TSST-1 |
| T422 | 1701-1705 | Protein | denotes | IL-1 |
| T423 | 1730-1734 | Protein | denotes | IL-2 |
| T424 | 1936-1942 | Protein | denotes | IL-1RA |
| T425 | 2033-2039 | Protein | denotes | IL-1RA |
BioNLP16_DUT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T849 | 1513-1517 | Protein | denotes | IL-6 |
| T850 | 1566-1572 | Protein | denotes | TSST-1 |
| T851 | 1581-1586 | Protein | denotes | IL-1β |
| T852 | 1587-1593 | Protein | denotes | IL-1RA |
| T853 | 1685-1691 | Protein | denotes | TSST-1 |
| T854 | 1701-1705 | Protein | denotes | IL-1 |
| T855 | 1730-1734 | Protein | denotes | IL-2 |
| T856 | 1936-1942 | Protein | denotes | IL-1RA |
| T857 | 2033-2039 | Protein | denotes | IL-1RA |
| T860 | 584-594 | Gene_expression | denotes | production |
| T861 | 465-475 | Positive_regulation | denotes | activation |
| T862 | 651-658 | Positive_regulation | denotes | induced |
| T863 | 795-802 | Binding | denotes | binding |
| T864 | 716-723 | Positive_regulation | denotes | induced |
| T865 | 896-906 | Gene_expression | denotes | production |
| T866 | 856-864 | Positive_regulation | denotes | increase |
| T867 | 1046-1053 | Binding | denotes | binding |
| T868 | 1026-1033 | Positive_regulation | denotes | induced |
| T869 | 1285-1293 | Positive_regulation | denotes | elevated |
| T870 | 1330-1337 | Binding | denotes | binding |
| T871 | 1318-1325 | Positive_regulation | denotes | induced |
| T872 | 1364-1371 | Positive_regulation | denotes | leading |
| T873 | 1389-1397 | Positive_regulation | denotes | increase |
| T874 | 1490-1499 | Negative_regulation | denotes | reduction |
| T875 | 1456-1463 | Positive_regulation | denotes | induced |
| T876 | 1573-1580 | Positive_regulation | denotes | induced |
| T877 | 1716-1726 | Gene_expression | denotes | production |
| T878 | 1692-1699 | Positive_regulation | denotes | induced |
| T879 | 1671-1680 | Negative_regulation | denotes | decreased |
| T880 | 2059-2068 | Regulation | denotes | modulated |
| T881 | 2015-2025 | Regulation | denotes | regulation |
| T827 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T828 | 436-442 | Protein | denotes | TSST-1 |
| T829 | 605-609 | Protein | denotes | IL-6 |
| T830 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T831 | 638-650 | Protein | denotes | interferon γ |
| T832 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T833 | 526-530 | Protein | denotes | NFAT |
| T834 | 549-555 | Protein | denotes | TSST-1 |
| T835 | 598-603 | Protein | denotes | IL-1β |
| T836 | 748-752 | Protein | denotes | IL-8 |
| T837 | 838-842 | Protein | denotes | IL-8 |
| T838 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T839 | 892-894 | Protein | denotes | RA |
| T840 | 996-1000 | Protein | denotes | IL-8 |
| T841 | 1108-1114 | Protein | denotes | IL-1RA |
| T842 | 1219-1225 | Protein | denotes | TSST-1 |
| T843 | 1311-1317 | Protein | denotes | TSST-1 |
| T844 | 1347-1353 | Protein | denotes | NFIL-6 |
| T845 | 1358-1362 | Protein | denotes | NFAT |
| T846 | 1401-1407 | Protein | denotes | IL-1RA |
| T847 | 1449-1455 | Protein | denotes | TSST-1 |
| T848 | 1503-1508 | Protein | denotes | IL-1β |
| R219 | T870 | T869 | themeOf | binding,elevated |
| R220 | T870 | T871 | themeOf | binding,induced |
| R221 | T870 | T871 | themeOf | binding,induced |
| R222 | T873 | T872 | themeOf | increase,leading |
| R349 | T843 | T871 | causeOf | TSST-1,induced |
| R350 | T843 | T871 | causeOf | TSST-1,induced |
| R351 | T844 | T870 | themeOf | NFIL-6,binding |
| R352 | T845 | T870 | themeOf | NFAT,binding |
| R353 | T846 | T873 | themeOf | IL-1RA,increase |
| R204 | T849 | T874 | themeOf | IL-6,reduction |
| R205 | T850 | T876 | causeOf | TSST-1,induced |
| R206 | T851 | T876 | themeOf | IL-1β,induced |
| R207 | T853 | T878 | causeOf | TSST-1,induced |
| R208 | T855 | T877 | themeOf | IL-2,production |
| R209 | T857 | T881 | themeOf | IL-1RA,regulation |
| R211 | T860 | T862 | themeOf | production,induced |
| R212 | T860 | T862 | themeOf | production,induced |
| R213 | T860 | T862 | themeOf | production,induced |
| R214 | T860 | T862 | themeOf | production,induced |
| R215 | T865 | T866 | themeOf | production,increase |
| R216 | T865 | T866 | themeOf | production,increase |
| R217 | T867 | T868 | themeOf | binding,induced |
| R218 | T870 | T869 | themeOf | binding,elevated |
| R223 | T877 | T878 | themeOf | production,induced |
| R224 | T877 | T879 | themeOf | production,decreased |
| R225 | T881 | T880 | themeOf | regulation,modulated |
| R338 | T829 | T860 | themeOf | IL-6,production |
| R339 | T830 | T860 | themeOf | tumor necrosis factor α,production |
| R340 | T831 | T860 | themeOf | interferon γ,production |
| R341 | T832 | T861 | themeOf | NFinterleukin(IL)-6,activation |
| R342 | T833 | T861 | themeOf | NFAT,activation |
| R343 | T835 | T860 | themeOf | IL-1β,production |
| R344 | T836 | T864 | themeOf | IL-8,induced |
| R345 | T837 | T863 | themeOf | IL-8,binding |
| R346 | T838 | T865 | themeOf | IL-1receptor antagonist,production |
| R347 | T839 | T865 | themeOf | RA,production |
| R348 | T841 | T867 | themeOf | IL-1RA,binding |
| R354 | T847 | T875 | themeOf | TSST-1,induced |
| R355 | T848 | T874 | themeOf | IL-1β,reduction |
BioNLP16_Messiy
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T469 | 1311-1317 | Protein | denotes | TSST-1 |
| T470 | 1347-1353 | Protein | denotes | NFIL-6 |
| T471 | 1358-1362 | Protein | denotes | NFAT |
| T472 | 1401-1407 | Protein | denotes | IL-1RA |
| T473 | 1449-1455 | Protein | denotes | TSST-1 |
| T474 | 1503-1508 | Protein | denotes | IL-1β |
| T475 | 1513-1517 | Protein | denotes | IL-6 |
| T476 | 1566-1572 | Protein | denotes | TSST-1 |
| T477 | 1581-1586 | Protein | denotes | IL-1β |
| T478 | 1587-1593 | Protein | denotes | IL-1RA |
| T479 | 1685-1691 | Protein | denotes | TSST-1 |
| T480 | 1701-1705 | Protein | denotes | IL-1 |
| T481 | 1730-1734 | Protein | denotes | IL-2 |
| T482 | 1936-1942 | Protein | denotes | IL-1RA |
| T483 | 2033-2039 | Protein | denotes | IL-1RA |
| T486 | 651-658 | Positive_regulation | denotes | induced |
| T487 | 584-594 | Gene_expression | denotes | production |
| T488 | 465-475 | Positive_regulation | denotes | activation |
| T489 | 716-723 | Positive_regulation | denotes | induced |
| T490 | 795-802 | Binding | denotes | binding |
| T491 | 896-906 | Gene_expression | denotes | production |
| T492 | 856-864 | Positive_regulation | denotes | increase |
| T493 | 1046-1053 | Binding | denotes | binding |
| T494 | 1026-1033 | Positive_regulation | denotes | induced |
| T495 | 1330-1337 | Binding | denotes | binding |
| T496 | 1318-1325 | Positive_regulation | denotes | induced |
| T497 | 1285-1293 | Positive_regulation | denotes | elevated |
| T498 | 1389-1397 | Positive_regulation | denotes | increase |
| T499 | 1490-1499 | Negative_regulation | denotes | reduction |
| T500 | 1456-1463 | Positive_regulation | denotes | induced |
| T501 | 1573-1580 | Positive_regulation | denotes | induced |
| T502 | 1692-1699 | Positive_regulation | denotes | induced |
| T503 | 1716-1726 | Gene_expression | denotes | production |
| T504 | 1671-1680 | Negative_regulation | denotes | decreased |
| T505 | 1706-1715 | Positive_regulation | denotes | dependent |
| T506 | 2015-2025 | Regulation | denotes | regulation |
| T453 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T454 | 436-442 | Protein | denotes | TSST-1 |
| T455 | 605-609 | Protein | denotes | IL-6 |
| T456 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T457 | 638-650 | Protein | denotes | interferon γ |
| T458 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T459 | 526-530 | Protein | denotes | NFAT |
| T460 | 549-555 | Protein | denotes | TSST-1 |
| T461 | 598-603 | Protein | denotes | IL-1β |
| T462 | 748-752 | Protein | denotes | IL-8 |
| T463 | 838-842 | Protein | denotes | IL-8 |
| T464 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T465 | 892-894 | Protein | denotes | RA |
| T466 | 996-1000 | Protein | denotes | IL-8 |
| T467 | 1108-1114 | Protein | denotes | IL-1RA |
| T468 | 1219-1225 | Protein | denotes | TSST-1 |
| R108 | T469 | T496 | causeOf | TSST-1,induced |
| R109 | T469 | T496 | causeOf | TSST-1,induced |
| R110 | T470 | T495 | themeOf | NFIL-6,binding |
| R111 | T471 | T495 | themeOf | NFAT,binding |
| R112 | T472 | T498 | themeOf | IL-1RA,increase |
| R120 | T481 | T503 | themeOf | IL-2,production |
| R121 | T483 | T506 | themeOf | IL-1RA,regulation |
| R123 | T487 | T486 | themeOf | production,induced |
| R124 | T487 | T486 | themeOf | production,induced |
| R125 | T487 | T486 | themeOf | production,induced |
| R126 | T487 | T486 | themeOf | production,induced |
| R127 | T491 | T492 | themeOf | production,increase |
| R128 | T491 | T492 | themeOf | production,increase |
| R129 | T493 | T494 | themeOf | binding,induced |
| R130 | T495 | T497 | themeOf | binding,elevated |
| R131 | T495 | T497 | themeOf | binding,elevated |
| R132 | T495 | T496 | themeOf | binding,induced |
| R133 | T495 | T496 | themeOf | binding,induced |
| R134 | T503 | T502 | themeOf | production,induced |
| R135 | T503 | T505 | themeOf | production,dependent |
| R136 | T503 | T504 | themeOf | production,decreased |
| R246 | T455 | T487 | themeOf | IL-6,production |
| R247 | T456 | T487 | themeOf | tumor necrosis factor α,production |
| R248 | T457 | T487 | themeOf | interferon γ,production |
| R249 | T457 | T486 | themeOf | interferon γ,induced |
| R250 | T458 | T488 | themeOf | NFinterleukin(IL)-6,activation |
| R251 | T459 | T488 | themeOf | NFAT,activation |
| R252 | T461 | T487 | themeOf | IL-1β,production |
| R253 | T461 | T486 | themeOf | IL-1β,induced |
| R254 | T462 | T489 | themeOf | IL-8,induced |
| R255 | T463 | T490 | themeOf | IL-8,binding |
| R256 | T464 | T491 | themeOf | IL-1receptor antagonist,production |
| R257 | T465 | T491 | themeOf | RA,production |
| R258 | T467 | T493 | themeOf | IL-1RA,binding |
| R113 | T473 | T500 | themeOf | TSST-1,induced |
| R114 | T474 | T499 | themeOf | IL-1β,reduction |
| R115 | T475 | T499 | themeOf | IL-6,reduction |
| R116 | T476 | T501 | causeOf | TSST-1,induced |
| R117 | T477 | T501 | themeOf | IL-1β,induced |
| R118 | T479 | T502 | causeOf | TSST-1,induced |
| R119 | T480 | T505 | causeOf | IL-1,dependent |
DLUT931
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T597 | 1581-1586 | Protein | denotes | IL-1β |
| T598 | 1587-1593 | Protein | denotes | IL-1RA |
| T599 | 1685-1691 | Protein | denotes | TSST-1 |
| T600 | 1701-1705 | Protein | denotes | IL-1 |
| T601 | 1730-1734 | Protein | denotes | IL-2 |
| T602 | 1936-1942 | Protein | denotes | IL-1RA |
| T603 | 2033-2039 | Protein | denotes | IL-1RA |
| T606 | 465-475 | Positive_regulation | denotes | activation |
| T607 | 584-594 | Gene_expression | denotes | production |
| T608 | 651-658 | Positive_regulation | denotes | induced |
| T609 | 716-723 | Positive_regulation | denotes | induced |
| T610 | 795-802 | Binding | denotes | binding |
| T611 | 896-906 | Gene_expression | denotes | production |
| T612 | 856-864 | Positive_regulation | denotes | increase |
| T613 | 1046-1053 | Binding | denotes | binding |
| T614 | 1026-1033 | Positive_regulation | denotes | induced |
| T615 | 1330-1337 | Binding | denotes | binding |
| T616 | 1389-1397 | Positive_regulation | denotes | increase |
| T617 | 1285-1293 | Positive_regulation | denotes | elevated |
| T618 | 1318-1325 | Positive_regulation | denotes | induced |
| T619 | 1490-1499 | Negative_regulation | denotes | reduction |
| T620 | 1573-1580 | Positive_regulation | denotes | induced |
| T621 | 1554-1561 | Negative_regulation | denotes | shifted |
| T622 | 1716-1726 | Gene_expression | denotes | production |
| T623 | 1692-1699 | Positive_regulation | denotes | induced |
| T624 | 1671-1680 | Negative_regulation | denotes | decreased |
| T625 | 2015-2025 | Regulation | denotes | regulation |
| T626 | 2059-2068 | Regulation | denotes | modulated |
| T573 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T574 | 436-442 | Protein | denotes | TSST-1 |
| T575 | 605-609 | Protein | denotes | IL-6 |
| T576 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T577 | 638-650 | Protein | denotes | interferon γ |
| T578 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T579 | 526-530 | Protein | denotes | NFAT |
| T580 | 549-555 | Protein | denotes | TSST-1 |
| T581 | 598-603 | Protein | denotes | IL-1β |
| T582 | 748-752 | Protein | denotes | IL-8 |
| T583 | 838-842 | Protein | denotes | IL-8 |
| T584 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T585 | 892-894 | Protein | denotes | RA |
| T586 | 996-1000 | Protein | denotes | IL-8 |
| T587 | 1108-1114 | Protein | denotes | IL-1RA |
| T588 | 1219-1225 | Protein | denotes | TSST-1 |
| T589 | 1311-1317 | Protein | denotes | TSST-1 |
| T590 | 1347-1353 | Protein | denotes | NFIL-6 |
| T591 | 1358-1362 | Protein | denotes | NFAT |
| T592 | 1401-1407 | Protein | denotes | IL-1RA |
| T593 | 1449-1455 | Protein | denotes | TSST-1 |
| T594 | 1503-1508 | Protein | denotes | IL-1β |
| T595 | 1513-1517 | Protein | denotes | IL-6 |
| T596 | 1566-1572 | Protein | denotes | TSST-1 |
| R146 | T610 | T609 | themeOf | binding,induced |
| R148 | T611 | T612 | themeOf | production,increase |
| R307 | T585 | T611 | themeOf | RA,production |
| R314 | T595 | T619 | themeOf | IL-6,reduction |
| R137 | T597 | T620 | themeOf | IL-1β,induced |
| R138 | T599 | T623 | causeOf | TSST-1,induced |
| R139 | T601 | T622 | themeOf | IL-2,production |
| R140 | T603 | T625 | themeOf | IL-1RA,regulation |
| R142 | T607 | T608 | themeOf | production,induced |
| R143 | T607 | T608 | themeOf | production,induced |
| R144 | T607 | T608 | themeOf | production,induced |
| R145 | T607 | T608 | themeOf | production,induced |
| R147 | T611 | T612 | themeOf | production,increase |
| R149 | T613 | T614 | themeOf | binding,induced |
| R150 | T615 | T617 | themeOf | binding,elevated |
| R151 | T615 | T618 | themeOf | binding,induced |
| R152 | T620 | T621 | themeOf | induced,shifted |
| R153 | T622 | T623 | themeOf | production,induced |
| R154 | T623 | T624 | themeOf | induced,decreased |
| R155 | T625 | T626 | themeOf | regulation,modulated |
| R298 | T575 | T607 | themeOf | IL-6,production |
| R299 | T576 | T607 | themeOf | tumor necrosis factor α,production |
| R300 | T577 | T607 | themeOf | interferon γ,production |
| R301 | T579 | T606 | themeOf | NFAT,activation |
| R302 | T581 | T607 | themeOf | IL-1β,production |
| R303 | T582 | T609 | themeOf | IL-8,induced |
| R304 | T582 | T610 | themeOf | IL-8,binding |
| R305 | T583 | T610 | themeOf | IL-8,binding |
| R306 | T584 | T611 | themeOf | IL-1receptor antagonist,production |
| R308 | T587 | T613 | themeOf | IL-1RA,binding |
| R309 | T589 | T618 | causeOf | TSST-1,induced |
| R310 | T590 | T615 | themeOf | NFIL-6,binding |
| R311 | T591 | T615 | themeOf | NFAT,binding |
| R312 | T592 | T616 | themeOf | IL-1RA,increase |
| R313 | T594 | T619 | themeOf | IL-1β,reduction |
| R315 | T596 | T620 | causeOf | TSST-1,induced |
bionlp-st-ge-2016-test-ihmc
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T761 | 341-347 | Entity | denotes | glucan |
| T762 | 1418-1424 | Entity | denotes | glucan |
| T763 | 1009-1015 | Entity | denotes | Glucan |
| T764 | 811-851 | Entity | denotes | to a consensus site in the IL-8 promoter |
| T765 | 526-556 | Protein | denotes | NFAT similar to LPS or TSST-1, |
| T766 | 1087-1091 | Protein | denotes | NFAT |
| T767 | 549-555 | Protein | denotes | TSST-1 |
| T768 | 1418-1434 | Entity | denotes | glucan phosphate |
| T769 | 1654-1660 | Entity | denotes | glucan |
| T770 | 1591-1593 | Protein | denotes | RA |
| T771 | 1727-1734 | Protein | denotes | of IL-2 |
| T772 | 745-752 | Protein | denotes | of IL-8 |
| T773 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T774 | 406-443 | Protein | denotes | toxic shock syndrome toxin 1 (TSST-1) |
| T775 | 1537-1553 | Entity | denotes | glucan phosphate |
| T777 | 286-334 | Entity | denotes | immune cells mediated by a fungal β-1→3-D-glucan |
| T778 | 436-442 | Protein | denotes | TSST-1 |
| T779 | 938-968 | Entity | denotes | glucan phosphate-treated cells |
| T781 | 1294-1302 | Protein | denotes | the LPS- |
| T782 | 1219-1225 | Protein | denotes | TSST-1 |
| T783 | 1081-1124 | Entity | denotes | a new NFAT site within the IL-1RA promoter, |
| T784 | 1358-1362 | Protein | denotes | NFAT |
| T785 | 1268-1274 | Entity | denotes | glucan |
| T786 | 834-851 | Entity | denotes | the IL-8 promoter |
| T787 | 938-944 | Entity | denotes | glucan |
| T788 | 1503-1508 | Protein | denotes | IL-1β |
| T789 | 638-678 | Protein | denotes | interferon γ induced by glucan phosphate |
| T790 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T791 | 1915-1951 | Entity | denotes | an anti-inflammatory IL-1RA-mediated |
| T792 | 375-402 | Entity | denotes | of lipopolysaccharide (LPS) |
| T793 | 881-895 | Entity | denotes | antagonist(RA) |
| T794 | 1581-1591 | Protein | denotes | IL-1β/IL-1 |
| T795 | 945-962 | Entity | denotes | phosphate-treated |
| T796 | 1701-1715 | Protein | denotes | IL-1-dependent |
| T797 | 1608-1628 | Entity | denotes | an anti-inflammatory |
| T798 | 680-686 | Entity | denotes | Glucan |
| T799 | 838-842 | Protein | denotes | IL-8 |
| T800 | 542-545 | Entity | denotes | LPS |
| T801 | 1212-1215 | Entity | denotes | LPS |
| T802 | 865-906 | Protein | denotes | in IL-1receptor antagonist(RA) production |
| T803 | 1566-1580 | Protein | denotes | TSST-1-induced |
| T804 | 398-401 | Entity | denotes | LPS |
| T805 | 1449-1463 | Protein | denotes | TSST-1-induced |
| T806 | 1057-1076 | Entity | denotes | a known NFIL-6 site |
| T807 | 1895-1951 | Entity | denotes | switching a pro- to an anti-inflammatory IL-1RA-mediated |
| T808 | 2033-2039 | Protein | denotes | IL-1RA |
| T809 | 868-872 | Protein | denotes | IL-1 |
| T810 | 1587-1591 | Protein | denotes | IL-1 |
| T811 | 1341-1345 | Protein | denotes | NFκB |
| T812 | 638-678 | Gene_expression | denotes | interferon γ induced by glucan phosphate |
| T813 | 638-678 | Positive_regulation | denotes | interferon γ induced by glucan phosphate |
| T814 | 1640-1734 | Negative_regulation | denotes | Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2 |
| T729 | 1347-1353 | Protein | denotes | NFIL-6 |
| T730 | 680-715 | Entity | denotes | Glucan phosphate-treated leukocytes |
| T731 | 605-609 | Protein | denotes | IL-6 |
| T732 | 1401-1407 | Protein | denotes | IL-1RA |
| T733 | 1685-1699 | Protein | denotes | TSST-1-induced |
| T734 | 1537-1543 | Entity | denotes | glucan |
| T735 | 892-894 | Protein | denotes | RA |
| T736 | 1104-1124 | Entity | denotes | the IL-1RA promoter, |
| T737 | 1581-1591 | Protein | denotes | IL-1β/IL-1 |
| T738 | 1065-1071 | Protein | denotes | NFIL-6 |
| T739 | 598-603 | Protein | denotes | IL-1β |
| T740 | 341-443 | Entity | denotes | glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1) |
| T743 | 687-704 | Entity | denotes | phosphate-treated |
| T744 | 919-920 | Entity | denotes | h |
| T746 | 2026-2045 | Protein | denotes | of the IL-1RA gene, |
| T747 | 1108-1114 | Protein | denotes | IL-1RA |
| T748 | 1654-1670 | Entity | denotes | glucan phosphate |
| T749 | 659-678 | Entity | denotes | by glucan phosphate |
| T750 | 765-766 | Entity | denotes | h |
| T751 | 1311-1325 | Protein | denotes | TSST-1-induced |
| T752 | 996-1000 | Protein | denotes | IL-8 |
| T753 | 662-668 | Entity | denotes | glucan |
| T754 | 803-810 | Protein | denotes | of NFκB |
| T755 | 1513-1517 | Protein | denotes | IL-6 |
| T757 | 1861-1869 | Protein | denotes | receptor |
| T817 | 557-678 | Gene_expression | denotes | we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate |
| T758 | 1263-1284 | Entity | denotes | that glucan phosphate |
| T759 | 1009-1033 | Entity | denotes | Glucan phosphate induced |
| T815 | 1681-1734 | Regulation | denotes | the TSST-1-induced, IL-1-dependent production of IL-2 |
| T816 | 557-678 | Gene_expression | denotes | we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate |
| T818 | 557-678 | Gene_expression | denotes | we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate |
| T819 | 557-678 | Gene_expression | denotes | we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate |
| T820 | 1861-1877 | Binding | denotes | receptor binding |
| T821 | 853-906 | Positive_regulation | denotes | An increase in IL-1receptor antagonist(RA) production |
| T822 | 795-851 | Binding | denotes | binding of NFκB to a consensus site in the IL-8 promoter |
| T823 | 1681-1734 | Gene_expression | denotes | the TSST-1-induced, IL-1-dependent production of IL-2 |
| R197 | T771 | T823 | themeOf | of IL-2,"the TSST-1-induced, IL-1-dependent production of IL-2" |
| R198 | T773 | T819 | themeOf | tumor necrosis factor α,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate" |
| R199 | T786 | T799 | partOf | the IL-8 promoter,IL-8 |
| R200 | T789 | T812 | themeOf | interferon γ induced by glucan phosphate,interferon γ induced by glucan phosphate |
| R201 | T789 | T813 | themeOf | interferon γ induced by glucan phosphate,interferon γ induced by glucan phosphate |
| R202 | T789 | T818 | themeOf | interferon γ induced by glucan phosphate,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate" |
| R203 | T796 | T815 | causeOf | IL-1-dependent,"the TSST-1-induced, IL-1-dependent production of IL-2" |
| R328 | T731 | T816 | themeOf | IL-6,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate" |
| R329 | T736 | T747 | partOf | "the IL-1RA promoter,",IL-1RA |
| R330 | T739 | T817 | themeOf | IL-1β,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate" |
| R331 | T748 | T814 | causeOf | glucan phosphate,"Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2" |
| R332 | T749 | T813 | causeOf | by glucan phosphate,interferon γ induced by glucan phosphate |
| R333 | T754 | T822 | themeOf | of NFκB,binding of NFκB to a consensus site in the IL-8 promoter |
| R334 | T757 | T820 | themeOf | receptor,receptor binding |
| R335 | T823 | T814 | themeOf | "the TSST-1-induced, IL-1-dependent production of IL-2","Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2" |
| R336 | T823 | T815 | themeOf | "the TSST-1-induced, IL-1-dependent production of IL-2","the TSST-1-induced, IL-1-dependent production of IL-2" |
bionlp-st-ge-2016-test-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T514 | 479-500 | Protein | denotes | nuclear factor (NF)κB |
| T518 | 605-609 | Protein | denotes | IL-6 |
| T519 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T520 | 638-650 | Protein | denotes | interferon γ |
| T521 | 465-475 | Positive_regulation | denotes | activation |
| T522 | 465-475 | Positive_regulation | denotes | activation |
| T523 | 465-475 | Positive_regulation | denotes | activation |
| T515 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T516 | 526-530 | Protein | denotes | NFAT |
| T517 | 598-603 | Protein | denotes | IL-1β |
| T524 | 584-594 | Gene_expression | denotes | production |
| T525 | 584-594 | Gene_expression | denotes | production |
| T526 | 584-594 | Gene_expression | denotes | production |
| T527 | 584-594 | Gene_expression | denotes | production |
| T528 | 651-658 | Positive_regulation | denotes | induced |
| T529 | 651-658 | Positive_regulation | denotes | induced |
| T530 | 651-658 | Positive_regulation | denotes | induced |
| T531 | 651-658 | Positive_regulation | denotes | induced |
| T532 | 748-752 | Protein | denotes | IL-8 |
| T533 | 806-810 | Protein | denotes | NFκB |
| T534 | 838-851 | Protein | denotes | IL-8 promoter |
| T535 | 738-744 | Gene_expression | denotes | amount |
| T536 | 795-802 | Binding | denotes | binding |
| T537 | 795-802 | Binding | denotes | binding |
| T538 | 716-723 | Positive_regulation | denotes | induced |
| T539 | 868-880 | Protein | denotes | IL-1receptor |
| T540 | 996-1000 | Protein | denotes | IL-8 |
| T541 | 1065-1076 | Protein | denotes | NFIL-6 site |
| T542 | 1087-1096 | Protein | denotes | NFAT site |
| T543 | 1108-1123 | Protein | denotes | IL-1RA promoter |
| T544 | 1046-1053 | Binding | denotes | binding |
| T545 | 1046-1053 | Binding | denotes | binding |
| T546 | 1135-1144 | Positive_regulation | denotes | confirmed |
| T547 | 1026-1033 | Positive_regulation | denotes | induced |
| T548 | 1026-1033 | Positive_regulation | denotes | induced |
| T549 | 1341-1345 | Protein | denotes | NFκB |
| T550 | 1347-1353 | Protein | denotes | NFIL-6 |
| T551 | 1358-1362 | Protein | denotes | NFAT |
| T552 | 1401-1407 | Protein | denotes | IL-1RA |
| T553 | 1330-1337 | Binding | denotes | binding |
| T554 | 1330-1337 | Binding | denotes | binding |
| T555 | 1330-1337 | Binding | denotes | binding |
| T556 | 1389-1397 | Positive_regulation | denotes | increase |
| T557 | 1285-1293 | Positive_regulation | denotes | elevated |
| T558 | 1285-1293 | Positive_regulation | denotes | elevated |
| T559 | 1285-1293 | Positive_regulation | denotes | elevated |
| T560 | 1503-1508 | Protein | denotes | IL-1β |
| T561 | 1513-1517 | Protein | denotes | IL-6 |
| T562 | 1490-1499 | Negative_regulation | denotes | reduction |
| T563 | 1490-1499 | Negative_regulation | denotes | reduction |
| T564 | 1701-1705 | Protein | denotes | IL-1 |
| T565 | 1730-1734 | Protein | denotes | IL-2 |
| T566 | 1716-1726 | Gene_expression | denotes | production |
| T567 | 1671-1680 | Negative_regulation | denotes | decreased |
| T568 | 2033-2044 | Protein | denotes | IL-1RA gene |
| T569 | 2015-2025 | Regulation | denotes | regulation |
| R263 | T514 | T521 | themeOf | nuclear factor (NF)κB,activation |
| R264 | T515 | T522 | themeOf | NFinterleukin(IL)-6,activation |
| R265 | T516 | T523 | themeOf | NFAT,activation |
| R266 | T517 | T524 | themeOf | IL-1β,production |
| R267 | T518 | T525 | themeOf | IL-6,production |
| R268 | T519 | T526 | themeOf | tumor necrosis factor α,production |
| R269 | T520 | T527 | themeOf | interferon γ,production |
| R270 | T524 | T528 | themeOf | production,induced |
| R271 | T525 | T529 | themeOf | production,induced |
| R272 | T526 | T530 | themeOf | production,induced |
| R273 | T527 | T531 | themeOf | production,induced |
| R274 | T532 | T535 | themeOf | IL-8,amount |
| R275 | T532 | T536 | themeOf | IL-8,binding |
| R276 | T533 | T536 | themeOf | NFκB,binding |
| R277 | T533 | T537 | themeOf | NFκB,binding |
| R278 | T534 | T537 | themeOf | IL-8 promoter,binding |
| R279 | T535 | T538 | themeOf | amount,induced |
| R280 | T542 | T544 | themeOf | NFAT site,binding |
| R281 | T543 | T545 | themeOf | IL-1RA promoter,binding |
| R282 | T543 | T546 | themeOf | IL-1RA promoter,confirmed |
| R283 | T544 | T547 | themeOf | binding,induced |
| R284 | T545 | T548 | themeOf | binding,induced |
| R285 | T549 | T553 | themeOf | NFκB,binding |
| R286 | T550 | T554 | themeOf | NFIL-6,binding |
| R287 | T551 | T555 | themeOf | NFAT,binding |
| R288 | T552 | T556 | themeOf | IL-1RA,increase |
| R289 | T553 | T557 | themeOf | binding,elevated |
| R290 | T554 | T558 | themeOf | binding,elevated |
| R291 | T555 | T559 | themeOf | binding,elevated |
| R292 | T560 | T562 | themeOf | IL-1β,reduction |
| R293 | T561 | T563 | themeOf | IL-6,reduction |
| R294 | T565 | T566 | themeOf | IL-2,production |
| R295 | T566 | T567 | themeOf | production,decreased |
| R296 | T568 | T569 | themeOf | IL-1RA gene,regulation |
testone
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T38 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T39 | 436-442 | Protein | denotes | TSST-1 |
| T40 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T41 | 526-530 | Protein | denotes | NFAT |
| T42 | 549-555 | Protein | denotes | TSST-1 |
| T43 | 598-603 | Protein | denotes | IL-1β |
| T44 | 605-609 | Protein | denotes | IL-6 |
| T45 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T46 | 638-650 | Protein | denotes | interferon γ |
| T47 | 748-752 | Protein | denotes | IL-8 |
| T48 | 838-842 | Protein | denotes | IL-8 |
| T49 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T50 | 892-894 | Protein | denotes | RA |
| T51 | 996-1000 | Protein | denotes | IL-8 |
| T52 | 1108-1114 | Protein | denotes | IL-1RA |
| T53 | 1219-1225 | Protein | denotes | TSST-1 |
| T54 | 1311-1317 | Protein | denotes | TSST-1 |
| T55 | 1347-1353 | Protein | denotes | NFIL-6 |
| T56 | 1358-1362 | Protein | denotes | NFAT |
| T57 | 1401-1407 | Protein | denotes | IL-1RA |
| T58 | 1449-1455 | Protein | denotes | TSST-1 |
| T59 | 1503-1508 | Protein | denotes | IL-1β |
| T60 | 1513-1517 | Protein | denotes | IL-6 |
| T61 | 1566-1572 | Protein | denotes | TSST-1 |
| T62 | 1581-1586 | Protein | denotes | IL-1β |
| T63 | 1587-1593 | Protein | denotes | IL-1RA |
| T64 | 1685-1691 | Protein | denotes | TSST-1 |
| T65 | 1701-1705 | Protein | denotes | IL-1 |
| T66 | 1730-1734 | Protein | denotes | IL-2 |
| T67 | 1936-1942 | Protein | denotes | IL-1RA |
| T68 | 2033-2039 | Protein | denotes | IL-1RA |
| T71 | 584-594 | Gene_expression | denotes | production |
| T72 | 651-658 | Positive_regulation | denotes | induced |
| T73 | 716-723 | Positive_regulation | denotes | induced |
| T74 | 795-802 | Binding | denotes | binding |
| T75 | 843-851 | Entity | denotes | promoter |
| T76 | 856-864 | Positive_regulation | denotes | increase |
| T77 | 881-891 | Negative_regulation | denotes | antagonist |
| T78 | 896-906 | Gene_expression | denotes | production |
| T79 | 1026-1033 | Positive_regulation | denotes | induced |
| T80 | 1046-1053 | Binding | denotes | binding |
| T81 | 1065-1076 | Entity | denotes | NFIL-6 site |
| T82 | 1092-1096 | Entity | denotes | site |
| T83 | 1115-1123 | Entity | denotes | promoter |
| T84 | 1285-1293 | Positive_regulation | denotes | elevated |
| T85 | 1318-1325 | Positive_regulation | denotes | induced |
| T86 | 1330-1337 | Binding | denotes | binding |
| T87 | 1389-1397 | Positive_regulation | denotes | increase |
| T88 | 1490-1499 | Negative_regulation | denotes | reduction |
| T89 | 1573-1580 | Positive_regulation | denotes | induced |
| T90 | 1671-1680 | Negative_regulation | denotes | decreased |
| T91 | 1692-1699 | Positive_regulation | denotes | induced |
| T92 | 1706-1715 | Positive_regulation | denotes | dependent |
| T93 | 1716-1726 | Gene_expression | denotes | production |
| T94 | 2015-2025 | Regulation | denotes | regulation |
| T95 | 2059-2068 | Regulation | denotes | modulated |
| R1 | T39 | T38 | equivalentTo | TSST-1,toxic shock syndrome toxin 1 |
| R2 | T43 | T71 | themeOf | IL-1β,production |
| R3 | T44 | T71 | themeOf | IL-6,production |
| R5 | T46 | T71 | themeOf | interferon γ,production |
| R6 | T49 | T78 | themeOf | IL-1receptor antagonist,production |
| R7 | T50 | T49 | equivalentTo | RA,IL-1receptor antagonist |
| R8 | T51 | T76 | causeOf | IL-8,increase |
| R9 | T54 | T85 | causeOf | TSST-1,induced |
| R10 | T55 | T86 | themeOf | NFIL-6,binding |
| R11 | T56 | T86 | themeOf | NFAT,binding |
| R12 | T57 | T87 | themeOf | IL-1RA,increase |
| R13 | T59 | T88 | themeOf | IL-1β,reduction |
| R14 | T60 | T88 | themeOf | IL-6,reduction |
| R15 | T61 | T89 | causeOf | TSST-1,induced |
| R16 | T62 | T89 | themeOf | IL-1β,induced |
| R17 | T63 | T89 | themeOf | IL-1RA,induced |
| R18 | T64 | T91 | causeOf | TSST-1,induced |
| R19 | T65 | T92 | causeOf | IL-1,dependent |
| R20 | T66 | T93 | themeOf | IL-2,production |
| R21 | T68 | T94 | themeOf | IL-1RA,regulation |
| R22 | T71 | T72 | themeOf | production,induced |
| R23 | T75 | T74 | themeOf | promoter,binding |
| R24 | T75 | T48 | partOf | promoter,IL-8 |
| R25 | T77 | T76 | themeOf | antagonist,increase |
| R26 | T78 | T76 | themeOf | production,increase |
| R27 | T80 | T79 | themeOf | binding,induced |
| R28 | T81 | T80 | themeOf | NFIL-6 site,binding |
| R29 | T81 | T52 | partOf | NFIL-6 site,IL-1RA |
| R30 | T83 | T80 | themeOf | promoter,binding |
| R31 | T83 | T52 | partOf | promoter,IL-1RA |
| R32 | T84 | T85 | themeOf | elevated,induced |
| R33 | T85 | T84 | themeOf | induced,elevated |
| R34 | T86 | T84 | themeOf | binding,elevated |
| R35 | T86 | T85 | themeOf | binding,induced |
| R36 | T91 | T90 | themeOf | induced,decreased |
| R37 | T92 | T90 | themeOf | dependent,decreased |
| R38 | T93 | T92 | themeOf | production,dependent |
| R4 | T45 | T71 | themeOf | tumor necrosis factor α,production |
| R39 | T94 | T95 | themeOf | regulation,modulated |
test3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T100 | 436-442 | Protein | denotes | TSST-1 |
| T101 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T102 | 526-530 | Protein | denotes | NFAT |
| T103 | 549-555 | Protein | denotes | TSST-1 |
| T104 | 598-603 | Protein | denotes | IL-1β |
| T99 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T105 | 605-609 | Protein | denotes | IL-6 |
| T106 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T107 | 638-650 | Protein | denotes | interferon γ |
| T108 | 748-752 | Protein | denotes | IL-8 |
| T109 | 838-842 | Protein | denotes | IL-8 |
| T110 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T111 | 892-894 | Protein | denotes | RA |
| T112 | 996-1000 | Protein | denotes | IL-8 |
| T113 | 1108-1114 | Protein | denotes | IL-1RA |
| T114 | 1219-1225 | Protein | denotes | TSST-1 |
| T115 | 1311-1317 | Protein | denotes | TSST-1 |
| T116 | 1347-1353 | Protein | denotes | NFIL-6 |
| T117 | 1358-1362 | Protein | denotes | NFAT |
| T118 | 1401-1407 | Protein | denotes | IL-1RA |
| T119 | 1449-1455 | Protein | denotes | TSST-1 |
| T120 | 1503-1508 | Protein | denotes | IL-1β |
| T121 | 1513-1517 | Protein | denotes | IL-6 |
| T122 | 1566-1572 | Protein | denotes | TSST-1 |
| T123 | 1581-1586 | Protein | denotes | IL-1β |
| T124 | 1587-1593 | Protein | denotes | IL-1RA |
| T125 | 1685-1691 | Protein | denotes | TSST-1 |
| T126 | 1701-1705 | Protein | denotes | IL-1 |
| T127 | 1730-1734 | Protein | denotes | IL-2 |
| T128 | 1936-1942 | Protein | denotes | IL-1RA |
| T129 | 2033-2039 | Protein | denotes | IL-1RA |
| T135 | 406-434 | Protein | denotes | toxic shock syndrome toxin 1 |
| T136 | 436-442 | Protein | denotes | TSST-1 |
| T137 | 465-475 | Positive_regulation | denotes | activation |
| T138 | 502-521 | Protein | denotes | NFinterleukin(IL)-6 |
| T139 | 526-530 | Protein | denotes | NFAT |
| T140 | 549-555 | Protein | denotes | TSST-1 |
| T141 | 584-594 | Gene_expression | denotes | production |
| T142 | 598-603 | Protein | denotes | IL-1β |
| T143 | 605-609 | Protein | denotes | IL-6 |
| T144 | 611-634 | Protein | denotes | tumor necrosis factor α |
| T145 | 638-650 | Protein | denotes | interferon γ |
| T146 | 651-658 | Positive_regulation | denotes | induced |
| T147 | 716-723 | Positive_regulation | denotes | induced |
| T148 | 748-752 | Protein | denotes | IL-8 |
| T149 | 795-802 | Binding | denotes | binding |
| T150 | 838-842 | Protein | denotes | IL-8 |
| T151 | 856-864 | Positive_regulation | denotes | increase |
| T152 | 868-891 | Protein | denotes | IL-1receptor antagonist |
| T153 | 892-894 | Protein | denotes | RA |
| T154 | 896-906 | Gene_expression | denotes | production |
| T155 | 996-1000 | Protein | denotes | IL-8 |
| T156 | 1026-1033 | Positive_regulation | denotes | induced |
| T157 | 1046-1053 | Binding | denotes | binding |
| T158 | 1108-1114 | Protein | denotes | IL-1RA |
| T159 | 1219-1225 | Protein | denotes | TSST-1 |
| T160 | 1285-1293 | Positive_regulation | denotes | elevated |
| T161 | 1311-1317 | Protein | denotes | TSST-1 |
| T162 | 1318-1325 | Positive_regulation | denotes | induced |
| T163 | 1330-1337 | Binding | denotes | binding |
| T164 | 1347-1353 | Protein | denotes | NFIL-6 |
| T165 | 1358-1362 | Protein | denotes | NFAT |
| T166 | 1389-1397 | Positive_regulation | denotes | increase |
| T167 | 1401-1407 | Protein | denotes | IL-1RA |
| T168 | 1449-1455 | Protein | denotes | TSST-1 |
| T169 | 1456-1463 | Positive_regulation | denotes | induced |
| T170 | 1490-1499 | Negative_regulation | denotes | reduction |
| T171 | 1503-1508 | Protein | denotes | IL-1β |
| T172 | 1513-1517 | Protein | denotes | IL-6 |
| T173 | 1566-1572 | Protein | denotes | TSST-1 |
| T174 | 1573-1580 | Positive_regulation | denotes | induced |
| T175 | 1581-1586 | Protein | denotes | IL-1β |
| T176 | 1587-1593 | Protein | denotes | IL-1RA |
| T177 | 1671-1680 | Negative_regulation | denotes | decreased |
| T178 | 1685-1691 | Protein | denotes | TSST-1 |
| T179 | 1692-1699 | Positive_regulation | denotes | induced |
| T180 | 1701-1705 | Protein | denotes | IL-1 |
| T181 | 1706-1715 | Positive_regulation | denotes | dependent |
| T182 | 1716-1726 | Gene_expression | denotes | production |
| T183 | 1730-1734 | Protein | denotes | IL-2 |
| T184 | 1936-1942 | Protein | denotes | IL-1RA |
| T185 | 2015-2025 | Regulation | denotes | regulation |
| T186 | 2033-2039 | Protein | denotes | IL-1RA |
| R66 | T172 | T170 | themeOf | IL-6,reduction |
| R67 | T173 | T174 | causeOf | TSST-1,induced |
| R68 | T175 | T174 | themeOf | IL-1β,induced |
| R69 | T176 | T174 | themeOf | IL-1RA,induced |
| R70 | T178 | T179 | causeOf | TSST-1,induced |
| R71 | T179 | T177 | themeOf | induced,decreased |
| R72 | T180 | T181 | causeOf | IL-1,dependent |
| R73 | T182 | T181 | themeOf | production,dependent |
| R74 | T183 | T182 | themeOf | IL-2,production |
| R75 | T186 | T185 | themeOf | IL-1RA,regulation |
| R41 | T136 | T135 | equivalentTo | TSST-1,toxic shock syndrome toxin 1 |
| R42 | T138 | T137 | themeOf | NFinterleukin(IL)-6,activation |
| R43 | T139 | T137 | themeOf | NFAT,activation |
| R44 | T140 | T137 | themeOf | TSST-1,activation |
| R45 | T141 | T146 | themeOf | production,induced |
| R46 | T142 | T141 | themeOf | IL-1β,production |
| R47 | T143 | T141 | themeOf | IL-6,production |
| R48 | T144 | T141 | themeOf | tumor necrosis factor α,production |
| R49 | T145 | T141 | themeOf | interferon γ,production |
| R50 | T148 | T149 | themeOf | IL-8,binding |
| R51 | T148 | T147 | themeOf | IL-8,induced |
| R52 | T152 | T154 | themeOf | IL-1receptor antagonist,production |
| R53 | T153 | T152 | equivalentTo | RA,IL-1receptor antagonist |
| R54 | T154 | T151 | themeOf | production,increase |
| R56 | T157 | T156 | themeOf | binding,induced |
| R57 | T161 | T162 | causeOf | TSST-1,induced |
| R58 | T162 | T160 | themeOf | induced,elevated |
| R59 | T163 | T162 | themeOf | binding,induced |
| R60 | T164 | T166 | causeOf | NFIL-6,increase |
| R61 | T164 | T163 | themeOf | NFIL-6,binding |
| R62 | T165 | T163 | themeOf | NFAT,binding |
| R63 | T167 | T166 | themeOf | IL-1RA,increase |
| R64 | T168 | T169 | causeOf | TSST-1,induced |
| R65 | T171 | T170 | themeOf | IL-1β,reduction |