PMC:1472690 / 13725-14136
Annnotations
pmc-enju-pas
{"project":"pmc-enju-pas","denotations":[{"id":"T5588","span":{"begin":409,"end":410},"obj":"-RRB-"},{"id":"T5587","span":{"begin":403,"end":409},"obj":"NN"},{"id":"T5586","span":{"begin":400,"end":402},"obj":"IN"},{"id":"T5585","span":{"begin":394,"end":399},"obj":"VB"},{"id":"T5584","span":{"begin":390,"end":393},"obj":"RB"},{"id":"T5583","span":{"begin":385,"end":389},"obj":"NN"},{"id":"T5582","span":{"begin":384,"end":385},"obj":"-LRB-"},{"id":"T5581","span":{"begin":378,"end":383},"obj":"NN"},{"id":"T5580","span":{"begin":368,"end":377},"obj":"NN"},{"id":"T5579","span":{"begin":365,"end":367},"obj":"CC"},{"id":"T5578","span":{"begin":358,"end":364},"obj":"NN"},{"id":"T5577","span":{"begin":355,"end":357},"obj":"TO"},{"id":"T5576","span":{"begin":346,"end":354},"obj":"VB"},{"id":"T5575","span":{"begin":341,"end":345},"obj":"WRB"},{"id":"T5574","span":{"begin":334,"end":340},"obj":"NN"},{"id":"T5573","span":{"begin":332,"end":333},"obj":"SYM"},{"id":"T5572","span":{"begin":329,"end":331},"obj":"NN"},{"id":"T5571","span":{"begin":319,"end":328},"obj":"VB"},{"id":"T5570","span":{"begin":308,"end":318},"obj":"NN"},{"id":"T5569","span":{"begin":303,"end":307},"obj":"NN"},{"id":"T5568","span":{"begin":300,"end":302},"obj":"IN"},{"id":"T5567","span":{"begin":289,"end":299},"obj":"NN"},{"id":"T5566","span":{"begin":277,"end":288},"obj":"JJ"},{"id":"T5565","span":{"begin":274,"end":276},"obj":"DT"},{"id":"T5564","span":{"begin":270,"end":273},"obj":"VB"},{"id":"T5563","span":{"begin":264,"end":269},"obj":"EX"},{"id":"T5562","span":{"begin":258,"end":262},"obj":"NN"},{"id":"T5561","span":{"begin":251,"end":257},"obj":"NN"},{"id":"T5560","span":{"begin":248,"end":250},"obj":"CC"},{"id":"T5559","span":{"begin":244,"end":247},"obj":"NN"},{"id":"T5558","span":{"begin":241,"end":243},"obj":"TO"},{"id":"T5557","span":{"begin":232,"end":240},"obj":"VB"},{"id":"T5556","span":{"begin":227,"end":231},"obj":"WRB"},{"id":"T5555","span":{"begin":216,"end":226},"obj":"NN"},{"id":"T5554","span":{"begin":211,"end":215},"obj":"NN"},{"id":"T5553","span":{"begin":208,"end":210},"obj":"IN"},{"id":"T5552","span":{"begin":199,"end":207},"obj":"NN"},{"id":"T5551","span":{"begin":183,"end":198},"obj":"JJ"},{"id":"T5550","span":{"begin":181,"end":182},"obj":"DT"},{"id":"T5549","span":{"begin":178,"end":180},"obj":"IN"},{"id":"T5548","span":{"begin":169,"end":177},"obj":"VB"},{"id":"T5547","span":{"begin":165,"end":168},"obj":"NN"},{"id":"T5546","span":{"begin":161,"end":164},"obj":"CC"},{"id":"T5545","span":{"begin":158,"end":160},"obj":"NN"},{"id":"T5544","span":{"begin":155,"end":157},"obj":"IN"},{"id":"T5543","span":{"begin":143,"end":154},"obj":"NN"},{"id":"T5542","span":{"begin":141,"end":142},"obj":"DT"},{"id":"T5541","span":{"begin":138,"end":139},"obj":"-RRB-"},{"id":"T5540","span":{"begin":134,"end":138},"obj":"CD"},{"id":"T5539","span":{"begin":132,"end":133},"obj":"SYM"},{"id":"T5538","span":{"begin":130,"end":131},"obj":"NN"},{"id":"T5537","span":{"begin":128,"end":129},"obj":"-COLON-"},{"id":"T5536","span":{"begin":126,"end":128},"obj":"CD"},{"id":"T5535","span":{"begin":124,"end":125},"obj":"SYM"},{"id":"T5534","span":{"begin":122,"end":123},"obj":"NN"},{"id":"T5533","span":{"begin":121,"end":122},"obj":"-LRB-"},{"id":"T5532","span":{"begin":119,"end":120},"obj":"NN"},{"id":"T5531","span":{"begin":116,"end":118},"obj":"CD"},{"id":"T5530","span":{"begin":113,"end":115},"obj":"IN"},{"id":"T5529","span":{"begin":102,"end":112},"obj":"RB"},{"id":"T5528","span":{"begin":100,"end":101},"obj":"-COMMA-"},{"id":"T5527","span":{"begin":93,"end":100},"obj":"NN"},{"id":"T5526","span":{"begin":86,"end":92},"obj":"NN"},{"id":"T5525","span":{"begin":81,"end":85},"obj":"IN"},{"id":"T5524","span":{"begin":70,"end":80},"obj":"NN"},{"id":"T5523","span":{"begin":67,"end":69},"obj":"IN"},{"id":"T5522","span":{"begin":65,"end":66},"obj":"-COMMA-"},{"id":"T5521","span":{"begin":55,"end":65},"obj":"NN"},{"id":"T5520","span":{"begin":50,"end":54},"obj":"NN"},{"id":"T5519","span":{"begin":38,"end":49},"obj":"JJ"},{"id":"T5518","span":{"begin":36,"end":37},"obj":"DT"},{"id":"T5517","span":{"begin":28,"end":35},"obj":"VB"},{"id":"T5516","span":{"begin":25,"end":27},"obj":"NN"},{"id":"T5515","span":{"begin":20,"end":24},"obj":"IN"},{"id":"T5514","span":{"begin":14,"end":19},"obj":"VB"},{"id":"T5513","span":{"begin":11,"end":13},"obj":"PRP"},{"id":"T5512","span":{"begin":6,"end":10},"obj":"NN"},{"id":"T5511","span":{"begin":4,"end":5},"obj":"-RRB-"},{"id":"T5510","span":{"begin":1,"end":4},"obj":"LS"},{"id":"T5509","span":{"begin":0,"end":1},"obj":"-LRB-"}],"relations":[{"id":"R3294","pred":"arg1Of","subj":"T5510","obj":"T5511"},{"id":"R3295","pred":"arg1Of","subj":"T5512","obj":"T5509"},{"id":"R3296","pred":"arg1Of","subj":"T5512","obj":"T5510"},{"id":"R3297","pred":"arg1Of","subj":"T5513","obj":"T5514"},{"id":"R3298","pred":"arg1Of","subj":"T5516","obj":"T5517"},{"id":"R3299","pred":"arg2Of","subj":"T5517","obj":"T5514"},{"id":"R3300","pred":"arg1Of","subj":"T5517","obj":"T5515"},{"id":"R3301","pred":"arg1Of","subj":"T5517","obj":"T5522"},{"id":"R3302","pred":"arg1Of","subj":"T5517","obj":"T5523"},{"id":"R3303","pred":"arg1Of","subj":"T5517","obj":"T5528"},{"id":"R3304","pred":"arg1Of","subj":"T5517","obj":"T5530"},{"id":"R3305","pred":"arg2Of","subj":"T5521","obj":"T5517"},{"id":"R3306","pred":"arg1Of","subj":"T5521","obj":"T5518"},{"id":"R3307","pred":"arg1Of","subj":"T5521","obj":"T5519"},{"id":"R3308","pred":"arg1Of","subj":"T5521","obj":"T5520"},{"id":"R3309","pred":"arg2Of","subj":"T5524","obj":"T5523"},{"id":"R3310","pred":"arg1Of","subj":"T5524","obj":"T5525"},{"id":"R3311","pred":"arg2Of","subj":"T5527","obj":"T5525"},{"id":"R3312","pred":"arg1Of","subj":"T5527","obj":"T5526"},{"id":"R3313","pred":"arg1Of","subj":"T5530","obj":"T5529"},{"id":"R3314","pred":"arg2Of","subj":"T5532","obj":"T5530"},{"id":"R3315","pred":"arg1Of","subj":"T5532","obj":"T5531"},{"id":"R3316","pred":"arg1Of","subj":"T5532","obj":"T5533"},{"id":"R3317","pred":"arg2Of","subj":"T5534","obj":"T5533"},{"id":"R3318","pred":"arg1Of","subj":"T5534","obj":"T5535"},{"id":"R3319","pred":"arg1Of","subj":"T5534","obj":"T5537"},{"id":"R3320","pred":"arg1Of","subj":"T5535","obj":"T5536"},{"id":"R3321","pred":"arg2Of","subj":"T5538","obj":"T5537"},{"id":"R3322","pred":"arg1Of","subj":"T5538","obj":"T5539"},{"id":"R3323","pred":"arg1Of","subj":"T5538","obj":"T5540"},{"id":"R3324","pred":"arg3Of","subj":"T5541","obj":"T5533"},{"id":"R3325","pred":"arg1Of","subj":"T5543","obj":"T5542"},{"id":"R3326","pred":"arg1Of","subj":"T5543","obj":"T5544"},{"id":"R3327","pred":"arg1Of","subj":"T5543","obj":"T5548"},{"id":"R3328","pred":"arg1Of","subj":"T5543","obj":"T5557"},{"id":"R3329","pred":"arg1Of","subj":"T5545","obj":"T5546"},{"id":"R3330","pred":"arg2Of","subj":"T5546","obj":"T5544"},{"id":"R3331","pred":"arg2Of","subj":"T5547","obj":"T5546"},{"id":"R3332","pred":"arg1Of","subj":"T5548","obj":"T5549"},{"id":"R3333","pred":"arg1Of","subj":"T5548","obj":"T5556"},{"id":"R3334","pred":"arg2Of","subj":"T5552","obj":"T5549"},{"id":"R3335","pred":"arg1Of","subj":"T5552","obj":"T5550"},{"id":"R3336","pred":"arg1Of","subj":"T5552","obj":"T5551"},{"id":"R3337","pred":"arg1Of","subj":"T5552","obj":"T5553"},{"id":"R3338","pred":"arg2Of","subj":"T5555","obj":"T5553"},{"id":"R3339","pred":"arg1Of","subj":"T5555","obj":"T5554"},{"id":"R3340","pred":"arg2Of","subj":"T5557","obj":"T5556"},{"id":"R3341","pred":"arg1Of","subj":"T5557","obj":"T5558"},{"id":"R3342","pred":"arg1Of","subj":"T5559","obj":"T5560"},{"id":"R3343","pred":"arg2Of","subj":"T5560","obj":"T5558"},{"id":"R3344","pred":"arg2Of","subj":"T5562","obj":"T5560"},{"id":"R3345","pred":"arg1Of","subj":"T5562","obj":"T5561"},{"id":"R3346","pred":"arg1Of","subj":"T5563","obj":"T5564"},{"id":"R3347","pred":"arg1Of","subj":"T5563","obj":"T5576"},{"id":"R3348","pred":"arg1Of","subj":"T5564","obj":"T5568"},{"id":"R3349","pred":"arg1Of","subj":"T5564","obj":"T5575"},{"id":"R3350","pred":"arg2Of","subj":"T5567","obj":"T5564"},{"id":"R3351","pred":"arg1Of","subj":"T5567","obj":"T5565"},{"id":"R3352","pred":"arg1Of","subj":"T5567","obj":"T5566"},{"id":"R3353","pred":"arg2Of","subj":"T5570","obj":"T5568"},{"id":"R3354","pred":"arg1Of","subj":"T5570","obj":"T5569"},{"id":"R3355","pred":"arg1Of","subj":"T5570","obj":"T5571"},{"id":"R3356","pred":"arg2Of","subj":"T5574","obj":"T5571"},{"id":"R3357","pred":"arg1Of","subj":"T5574","obj":"T5572"},{"id":"R3358","pred":"arg1Of","subj":"T5574","obj":"T5573"},{"id":"R3359","pred":"arg2Of","subj":"T5576","obj":"T5575"},{"id":"R3360","pred":"arg1Of","subj":"T5576","obj":"T5577"},{"id":"R3361","pred":"arg1Of","subj":"T5578","obj":"T5579"},{"id":"R3362","pred":"arg2Of","subj":"T5579","obj":"T5577"},{"id":"R3363","pred":"arg2Of","subj":"T5581","obj":"T5579"},{"id":"R3364","pred":"arg1Of","subj":"T5581","obj":"T5580"},{"id":"R3365","pred":"arg1Of","subj":"T5581","obj":"T5582"},{"id":"R3366","pred":"arg2Of","subj":"T5583","obj":"T5582"},{"id":"R3367","pred":"arg2Of","subj":"T5583","obj":"T5585"},{"id":"R3368","pred":"arg1Of","subj":"T5585","obj":"T5584"},{"id":"R3369","pred":"arg1Of","subj":"T5585","obj":"T5586"},{"id":"R3370","pred":"arg2Of","subj":"T5587","obj":"T5586"},{"id":"R3371","pred":"arg3Of","subj":"T5588","obj":"T5582"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
bionlp-st-ge-2016-test-proteins
{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T4954","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T4953","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T4952","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T4951","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T4950","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T4949","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T4948","span":{"begin":6,"end":10},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
bionlp-st-ge-2016-uniprot
{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T6037","span":{"begin":371,"end":377},"obj":"http://www.uniprot.org/uniprot/P06886"},{"id":"T6036","span":{"begin":358,"end":364},"obj":"http://www.uniprot.org/uniprot/P06886"},{"id":"T6035","span":{"begin":334,"end":340},"obj":"http://www.uniprot.org/uniprot/P06886"},{"id":"T6061","span":{"begin":303,"end":307},"obj":"http://www.uniprot.org/uniprot/P10145"},{"id":"T6060","span":{"begin":211,"end":215},"obj":"http://www.uniprot.org/uniprot/P10145"},{"id":"T6059","span":{"begin":50,"end":54},"obj":"http://www.uniprot.org/uniprot/P10145"},{"id":"T6058","span":{"begin":6,"end":10},"obj":"http://www.uniprot.org/uniprot/P10145"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
GO-BP
{"project":"GO-BP","denotations":[{"id":"T4768","span":{"begin":303,"end":318},"obj":"http://purl.obolibrary.org/obo/GO_0032637"},{"id":"T4767","span":{"begin":211,"end":226},"obj":"http://purl.obolibrary.org/obo/GO_0032637"},{"id":"T4766","span":{"begin":50,"end":65},"obj":"http://purl.obolibrary.org/obo/GO_0032637"},{"id":"T4765","span":{"begin":303,"end":318},"obj":"http://purl.obolibrary.org/obo/GO_0032677"},{"id":"T4764","span":{"begin":211,"end":226},"obj":"http://purl.obolibrary.org/obo/GO_0032677"},{"id":"T4763","span":{"begin":50,"end":65},"obj":"http://purl.obolibrary.org/obo/GO_0032677"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
GO-MF
{"project":"GO-MF","denotations":[{"id":"T5001","span":{"begin":303,"end":307},"obj":"http://purl.obolibrary.org/obo/GO_0005153"},{"id":"T5000","span":{"begin":211,"end":215},"obj":"http://purl.obolibrary.org/obo/GO_0005153"},{"id":"T4999","span":{"begin":50,"end":54},"obj":"http://purl.obolibrary.org/obo/GO_0005153"},{"id":"T4998","span":{"begin":6,"end":10},"obj":"http://purl.obolibrary.org/obo/GO_0005153"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
sentences
{"project":"sentences","denotations":[{"id":"T4734","span":{"begin":264,"end":411},"obj":"Sentence"},{"id":"T4733","span":{"begin":141,"end":263},"obj":"Sentence"},{"id":"T4732","span":{"begin":11,"end":140},"obj":"Sentence"},{"id":"T4731","span":{"begin":0,"end":10},"obj":"Sentence"},{"id":"T104","span":{"begin":0,"end":10},"obj":"Sentence"},{"id":"T105","span":{"begin":11,"end":140},"obj":"Sentence"},{"id":"T106","span":{"begin":141,"end":263},"obj":"Sentence"},{"id":"T107","span":{"begin":264,"end":411},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
simple1
{"project":"simple1","denotations":[{"id":"T5131","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T5130","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T5129","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T5128","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T5127","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T5126","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T5125","span":{"begin":6,"end":10},"obj":"Protein"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
BioNLP16_DUT
{"project":"BioNLP16_DUT","denotations":[{"id":"T7739","span":{"begin":308,"end":318},"obj":"Gene_expression"},{"id":"T7738","span":{"begin":169,"end":177},"obj":"Positive_regulation"},{"id":"T7737","span":{"begin":216,"end":226},"obj":"Gene_expression"},{"id":"T7736","span":{"begin":199,"end":207},"obj":"Positive_regulation"},{"id":"T7735","span":{"begin":28,"end":35},"obj":"Positive_regulation"},{"id":"T7734","span":{"begin":55,"end":65},"obj":"Gene_expression"},{"id":"T7678","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T7677","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T7676","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T7675","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T7674","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T7673","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T7672","span":{"begin":6,"end":10},"obj":"Protein"}],"relations":[{"id":"R5013","pred":"themeOf","subj":"T7673","obj":"T7734"},{"id":"R5019","pred":"themeOf","subj":"T7674","obj":"T7737"},{"id":"R5020","pred":"themeOf","subj":"T7675","obj":"T7739"},{"id":"R5021","pred":"themeOf","subj":"T7676","obj":"T7739"},{"id":"R5027","pred":"themeOf","subj":"T7734","obj":"T7735"},{"id":"R5028","pred":"themeOf","subj":"T7736","obj":"T7738"},{"id":"R5029","pred":"themeOf","subj":"T7737","obj":"T7736"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
BioNLP16_Messiy
{"project":"BioNLP16_Messiy","denotations":[{"id":"T6191","span":{"begin":319,"end":328},"obj":"Positive_regulation"},{"id":"T6190","span":{"begin":308,"end":318},"obj":"Gene_expression"},{"id":"T6189","span":{"begin":289,"end":299},"obj":"Regulation"},{"id":"T6188","span":{"begin":169,"end":177},"obj":"Positive_regulation"},{"id":"T6187","span":{"begin":199,"end":207},"obj":"Positive_regulation"},{"id":"T6186","span":{"begin":216,"end":226},"obj":"Gene_expression"},{"id":"T6185","span":{"begin":28,"end":35},"obj":"Positive_regulation"},{"id":"T6184","span":{"begin":55,"end":65},"obj":"Gene_expression"},{"id":"T6128","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T6127","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T6126","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T6125","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T6124","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T6123","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T6122","span":{"begin":6,"end":10},"obj":"Protein"}],"relations":[{"id":"R3826","pred":"themeOf","subj":"T6123","obj":"T6184"},{"id":"R3830","pred":"themeOf","subj":"T6124","obj":"T6186"},{"id":"R3832","pred":"themeOf","subj":"T6125","obj":"T6190"},{"id":"R3834","pred":"themeOf","subj":"T6126","obj":"T6190"},{"id":"R3848","pred":"themeOf","subj":"T6184","obj":"T6185"},{"id":"R3850","pred":"themeOf","subj":"T6186","obj":"T6187"},{"id":"R3851","pred":"themeOf","subj":"T6187","obj":"T6188"},{"id":"R3854","pred":"themeOf","subj":"T6190","obj":"T6191"},{"id":"R3855","pred":"themeOf","subj":"T6190","obj":"T6191"},{"id":"R3856","pred":"themeOf","subj":"T6190","obj":"T6189"},{"id":"R3857","pred":"themeOf","subj":"T6190","obj":"T6189"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
DLUT931
{"project":"DLUT931","denotations":[{"id":"T6337","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T6336","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T6335","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T6334","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T6333","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T6332","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T6331","span":{"begin":6,"end":10},"obj":"Protein"},{"id":"T6398","span":{"begin":289,"end":299},"obj":"Regulation"},{"id":"T6397","span":{"begin":319,"end":328},"obj":"Positive_regulation"},{"id":"T6396","span":{"begin":308,"end":318},"obj":"Gene_expression"},{"id":"T6395","span":{"begin":169,"end":177},"obj":"Positive_regulation"},{"id":"T6394","span":{"begin":199,"end":207},"obj":"Positive_regulation"},{"id":"T6393","span":{"begin":216,"end":226},"obj":"Gene_expression"},{"id":"T6392","span":{"begin":28,"end":35},"obj":"Positive_regulation"},{"id":"T6391","span":{"begin":55,"end":65},"obj":"Gene_expression"}],"relations":[{"id":"R3938","pred":"themeOf","subj":"T6332","obj":"T6391"},{"id":"R3939","pred":"themeOf","subj":"T6333","obj":"T6393"},{"id":"R3941","pred":"themeOf","subj":"T6334","obj":"T6396"},{"id":"R3942","pred":"themeOf","subj":"T6335","obj":"T6396"},{"id":"R3973","pred":"themeOf","subj":"T6391","obj":"T6392"},{"id":"R3976","pred":"themeOf","subj":"T6393","obj":"T6394"},{"id":"R3980","pred":"themeOf","subj":"T6394","obj":"T6395"},{"id":"R3982","pred":"themeOf","subj":"T6396","obj":"T6397"},{"id":"R3987","pred":"themeOf","subj":"T6396","obj":"T6398"},{"id":"R3988","pred":"themeOf","subj":"T6396","obj":"T6397"},{"id":"R3990","pred":"themeOf","subj":"T6396","obj":"T6398"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
bionlp-st-ge-2016-test-ihmc
{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T7619","span":{"begin":119,"end":120},"obj":"Entity"},{"id":"T7613","span":{"begin":6,"end":10},"obj":"Protein"},{"id":"T7578","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T7571","span":{"begin":258,"end":262},"obj":"Protein"},{"id":"T7563","span":{"begin":122,"end":123},"obj":"Entity"},{"id":"T7541","span":{"begin":158,"end":160},"obj":"Protein"},{"id":"T7533","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T7532","span":{"begin":251,"end":257},"obj":"Entity"},{"id":"T7520","span":{"begin":130,"end":131},"obj":"Entity"},{"id":"T7513","span":{"begin":165,"end":168},"obj":"Entity"},{"id":"T7512","span":{"begin":251,"end":257},"obj":"Protein"},{"id":"T7511","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T7639","span":{"begin":254,"end":257},"obj":"Entity"},{"id":"T7629","span":{"begin":244,"end":247},"obj":"Entity"},{"id":"T7794","span":{"begin":36,"end":66},"obj":"Gene_expression"},{"id":"T7793","span":{"begin":178,"end":226},"obj":"Positive_regulation"},{"id":"T7791","span":{"begin":208,"end":226},"obj":"Gene_expression"},{"id":"T7784","span":{"begin":303,"end":331},"obj":"Gene_expression"},{"id":"T7775","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T7774","span":{"begin":355,"end":382},"obj":"Protein"},{"id":"T7767","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T7765","span":{"begin":303,"end":307},"obj":"Protein"}],"relations":[{"id":"R4942","pred":"themeOf","subj":"T7511","obj":"T7794"},{"id":"R5050","pred":"themeOf","subj":"T7765","obj":"T7784"},{"id":"R5051","pred":"themeOf","subj":"T7775","obj":"T7791"},{"id":"R5054","pred":"themeOf","subj":"T7791","obj":"T7793"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
bionlp-st-ge-2016-spacy-parsed
{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T6956","span":{"begin":410,"end":411},"obj":"."},{"id":"T6955","span":{"begin":409,"end":410},"obj":"-RRB-"},{"id":"T6954","span":{"begin":403,"end":409},"obj":"NN"},{"id":"T6953","span":{"begin":400,"end":402},"obj":"IN"},{"id":"T6952","span":{"begin":394,"end":399},"obj":"VBN"},{"id":"T6951","span":{"begin":390,"end":393},"obj":"RB"},{"id":"T6950","span":{"begin":385,"end":389},"obj":"NNS"},{"id":"T6949","span":{"begin":384,"end":385},"obj":"-LRB-"},{"id":"T6948","span":{"begin":382,"end":383},"obj":"."},{"id":"T6947","span":{"begin":378,"end":382},"obj":"NN"},{"id":"T6946","span":{"begin":375,"end":377},"obj":"CD"},{"id":"T6945","span":{"begin":368,"end":375},"obj":"NNP"},{"id":"T6944","span":{"begin":365,"end":367},"obj":"CC"},{"id":"T6943","span":{"begin":358,"end":364},"obj":"CD"},{"id":"T6942","span":{"begin":355,"end":357},"obj":"TO"},{"id":"T6941","span":{"begin":346,"end":354},"obj":"VBN"},{"id":"T6940","span":{"begin":341,"end":345},"obj":"WRB"},{"id":"T6939","span":{"begin":334,"end":340},"obj":"NNP"},{"id":"T6938","span":{"begin":332,"end":333},"obj":"NNP"},{"id":"T6937","span":{"begin":329,"end":331},"obj":"NNP"},{"id":"T6936","span":{"begin":319,"end":328},"obj":"VBG"},{"id":"T6935","span":{"begin":308,"end":318},"obj":"NN"},{"id":"T6934","span":{"begin":303,"end":307},"obj":"JJ"},{"id":"T6933","span":{"begin":300,"end":302},"obj":"IN"},{"id":"T6932","span":{"begin":289,"end":299},"obj":"NN"},{"id":"T6931","span":{"begin":277,"end":288},"obj":"JJ"},{"id":"T6930","span":{"begin":274,"end":276},"obj":"DT"},{"id":"T6929","span":{"begin":270,"end":273},"obj":"VBD"},{"id":"T6928","span":{"begin":264,"end":269},"obj":"EX"},{"id":"T6927","span":{"begin":262,"end":263},"obj":"."},{"id":"T6926","span":{"begin":258,"end":262},"obj":"NN"},{"id":"T6925","span":{"begin":251,"end":257},"obj":"NNP"},{"id":"T6924","span":{"begin":248,"end":250},"obj":"CC"},{"id":"T6923","span":{"begin":244,"end":247},"obj":"NNP"},{"id":"T6922","span":{"begin":241,"end":243},"obj":"TO"},{"id":"T6921","span":{"begin":232,"end":240},"obj":"VBN"},{"id":"T6920","span":{"begin":227,"end":231},"obj":"WRB"},{"id":"T6919","span":{"begin":216,"end":226},"obj":"NN"},{"id":"T6918","span":{"begin":211,"end":215},"obj":"JJ"},{"id":"T6917","span":{"begin":208,"end":210},"obj":"IN"},{"id":"T6916","span":{"begin":199,"end":207},"obj":"NN"},{"id":"T6915","span":{"begin":183,"end":198},"obj":"JJ"},{"id":"T6914","span":{"begin":181,"end":182},"obj":"DT"},{"id":"T6913","span":{"begin":178,"end":180},"obj":"IN"},{"id":"T6912","span":{"begin":169,"end":177},"obj":"VBD"},{"id":"T6911","span":{"begin":165,"end":168},"obj":"NNP"},{"id":"T6910","span":{"begin":161,"end":164},"obj":"CC"},{"id":"T6909","span":{"begin":158,"end":160},"obj":"NNP"},{"id":"T6908","span":{"begin":155,"end":157},"obj":"IN"},{"id":"T6907","span":{"begin":143,"end":154},"obj":"NN"},{"id":"T6906","span":{"begin":141,"end":142},"obj":"DT"},{"id":"T6905","span":{"begin":139,"end":140},"obj":"."},{"id":"T6904","span":{"begin":138,"end":139},"obj":"-RRB-"},{"id":"T6903","span":{"begin":134,"end":138},"obj":"CD"},{"id":"T6902","span":{"begin":132,"end":133},"obj":"NN"},{"id":"T6901","span":{"begin":130,"end":131},"obj":"VB"},{"id":"T6900","span":{"begin":128,"end":129},"obj":":"},{"id":"T6899","span":{"begin":126,"end":128},"obj":"CD"},{"id":"T6898","span":{"begin":124,"end":125},"obj":"SYM"},{"id":"T6897","span":{"begin":122,"end":123},"obj":"FW"},{"id":"T6896","span":{"begin":121,"end":122},"obj":"-LRB-"},{"id":"T6895","span":{"begin":119,"end":120},"obj":"NN"},{"id":"T6894","span":{"begin":116,"end":118},"obj":"CD"},{"id":"T6893","span":{"begin":113,"end":115},"obj":"IN"},{"id":"T6892","span":{"begin":102,"end":112},"obj":"RB"},{"id":"T6891","span":{"begin":100,"end":101},"obj":","},{"id":"T6890","span":{"begin":93,"end":100},"obj":"NN"},{"id":"T6889","span":{"begin":86,"end":92},"obj":"JJ"},{"id":"T6888","span":{"begin":81,"end":85},"obj":"IN"},{"id":"T6887","span":{"begin":70,"end":80},"obj":"NN"},{"id":"T6886","span":{"begin":67,"end":69},"obj":"IN"},{"id":"T6885","span":{"begin":65,"end":66},"obj":","},{"id":"T6884","span":{"begin":55,"end":65},"obj":"NN"},{"id":"T6883","span":{"begin":50,"end":54},"obj":"NN"},{"id":"T6882","span":{"begin":38,"end":49},"obj":"JJ"},{"id":"T6881","span":{"begin":36,"end":37},"obj":"DT"},{"id":"T6880","span":{"begin":28,"end":35},"obj":"VBD"},{"id":"T6879","span":{"begin":25,"end":27},"obj":"NNP"},{"id":"T6878","span":{"begin":20,"end":24},"obj":"IN"},{"id":"T6877","span":{"begin":14,"end":19},"obj":"VBD"},{"id":"T6876","span":{"begin":11,"end":13},"obj":"PRP"},{"id":"T6875","span":{"begin":6,"end":10},"obj":"NN"},{"id":"T6874","span":{"begin":4,"end":5},"obj":"-RRB-"},{"id":"T6873","span":{"begin":1,"end":4},"obj":"FW"},{"id":"T6872","span":{"begin":0,"end":1},"obj":"-LRB-"}],"relations":[{"id":"R4358","pred":"punct","subj":"T6872","obj":"T6873"},{"id":"R4360","pred":"ROOT","subj":"T6873","obj":"T6873"},{"id":"R4361","pred":"punct","subj":"T6874","obj":"T6873"},{"id":"R4363","pred":"intj","subj":"T6875","obj":"T6877"},{"id":"R4364","pred":"nsubj","subj":"T6876","obj":"T6877"},{"id":"R4365","pred":"ROOT","subj":"T6877","obj":"T6877"},{"id":"R4366","pred":"mark","subj":"T6878","obj":"T6880"},{"id":"R4368","pred":"nsubj","subj":"T6879","obj":"T6880"},{"id":"R4369","pred":"ccomp","subj":"T6880","obj":"T6877"},{"id":"R4371","pred":"det","subj":"T6881","obj":"T6884"},{"id":"R4372","pred":"amod","subj":"T6882","obj":"T6884"},{"id":"R4374","pred":"compound","subj":"T6883","obj":"T6884"},{"id":"R4375","pred":"dobj","subj":"T6884","obj":"T6880"},{"id":"R4376","pred":"punct","subj":"T6885","obj":"T6880"},{"id":"R4377","pred":"prep","subj":"T6886","obj":"T6880"},{"id":"R4379","pred":"pobj","subj":"T6887","obj":"T6886"},{"id":"R4380","pred":"prep","subj":"T6888","obj":"T6887"},{"id":"R4381","pred":"amod","subj":"T6889","obj":"T6890"},{"id":"R4383","pred":"pobj","subj":"T6890","obj":"T6888"},{"id":"R4384","pred":"punct","subj":"T6891","obj":"T6880"},{"id":"R4386","pred":"advmod","subj":"T6892","obj":"T6893"},{"id":"R4387","pred":"prep","subj":"T6893","obj":"T6880"},{"id":"R4388","pred":"nummod","subj":"T6894","obj":"T6895"},{"id":"R4389","pred":"pobj","subj":"T6895","obj":"T6893"},{"id":"R4390","pred":"punct","subj":"T6896","obj":"T6899"},{"id":"R4391","pred":"advmod","subj":"T6897","obj":"T6899"},{"id":"R4392","pred":"punct","subj":"T6898","obj":"T6899"},{"id":"R4394","pred":"appos","subj":"T6899","obj":"T6895"},{"id":"R4395","pred":"punct","subj":"T6900","obj":"T6901"},{"id":"R4396","pred":"ROOT","subj":"T6901","obj":"T6901"},{"id":"R4397","pred":"compound","subj":"T6902","obj":"T6903"},{"id":"R4399","pred":"npadvmod","subj":"T6903","obj":"T6901"},{"id":"R4400","pred":"punct","subj":"T6904","obj":"T6901"},{"id":"R4401","pred":"punct","subj":"T6905","obj":"T6901"},{"id":"R4403","pred":"det","subj":"T6906","obj":"T6907"},{"id":"R4404","pred":"nsubj","subj":"T6907","obj":"T6912"},{"id":"R4405","pred":"prep","subj":"T6908","obj":"T6907"},{"id":"R4407","pred":"pobj","subj":"T6909","obj":"T6908"},{"id":"R4408","pred":"cc","subj":"T6910","obj":"T6909"},{"id":"R4409","pred":"conj","subj":"T6911","obj":"T6909"},{"id":"R4411","pred":"ROOT","subj":"T6912","obj":"T6912"},{"id":"R4412","pred":"prep","subj":"T6913","obj":"T6912"},{"id":"R4413","pred":"det","subj":"T6914","obj":"T6916"},{"id":"R4415","pred":"amod","subj":"T6915","obj":"T6916"},{"id":"R4416","pred":"pobj","subj":"T6916","obj":"T6913"},{"id":"R4417","pred":"prep","subj":"T6917","obj":"T6916"},{"id":"R4419","pred":"amod","subj":"T6918","obj":"T6919"},{"id":"R4420","pred":"pobj","subj":"T6919","obj":"T6917"},{"id":"R4421","pred":"advmod","subj":"T6920","obj":"T6921"},{"id":"R4423","pred":"advcl","subj":"T6921","obj":"T6912"},{"id":"R4424","pred":"prep","subj":"T6922","obj":"T6921"},{"id":"R4425","pred":"pobj","subj":"T6923","obj":"T6922"},{"id":"R4429","pred":"cc","subj":"T6924","obj":"T6923"},{"id":"R4430","pred":"compound","subj":"T6925","obj":"T6926"},{"id":"R4432","pred":"conj","subj":"T6926","obj":"T6923"},{"id":"R4433","pred":"punct","subj":"T6927","obj":"T6912"},{"id":"R4437","pred":"expl","subj":"T6928","obj":"T6929"},{"id":"R4438","pred":"ROOT","subj":"T6929","obj":"T6929"},{"id":"R4439","pred":"det","subj":"T6930","obj":"T6932"},{"id":"R4440","pred":"amod","subj":"T6931","obj":"T6932"},{"id":"R4441","pred":"attr","subj":"T6932","obj":"T6929"},{"id":"R4443","pred":"prep","subj":"T6933","obj":"T6932"},{"id":"R4444","pred":"amod","subj":"T6934","obj":"T6935"},{"id":"R4446","pred":"pobj","subj":"T6935","obj":"T6933"},{"id":"R4447","pred":"prep","subj":"T6936","obj":"T6929"},{"id":"R4449","pred":"compound","subj":"T6937","obj":"T6939"},{"id":"R4450","pred":"compound","subj":"T6938","obj":"T6939"},{"id":"R4451","pred":"dobj","subj":"T6939","obj":"T6936"},{"id":"R4453","pred":"advmod","subj":"T6940","obj":"T6941"},{"id":"R4454","pred":"advcl","subj":"T6941","obj":"T6929"},{"id":"R4455","pred":"prep","subj":"T6942","obj":"T6941"},{"id":"R4457","pred":"pobj","subj":"T6943","obj":"T6942"},{"id":"R4458","pred":"cc","subj":"T6944","obj":"T6943"},{"id":"R4459","pred":"dep","subj":"T6945","obj":"T6947"},{"id":"R4461","pred":"nummod","subj":"T6946","obj":"T6947"},{"id":"R4462","pred":"conj","subj":"T6947","obj":"T6943"},{"id":"R4463","pred":"punct","subj":"T6948","obj":"T6929"},{"id":"R4465","pred":"punct","subj":"T6949","obj":"T6950"},{"id":"R4466","pred":"ROOT","subj":"T6950","obj":"T6950"},{"id":"R4468","pred":"neg","subj":"T6951","obj":"T6952"},{"id":"R4469","pred":"acl","subj":"T6952","obj":"T6950"},{"id":"R4470","pred":"prep","subj":"T6953","obj":"T6952"},{"id":"R4472","pred":"pobj","subj":"T6954","obj":"T6953"},{"id":"R4473","pred":"punct","subj":"T6955","obj":"T6950"},{"id":"R4474","pred":"punct","subj":"T6956","obj":"T6950"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
bionlp-st-ge-2016-test-tees
{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T6246","span":{"begin":368,"end":382},"obj":"Protein"},{"id":"T6245","span":{"begin":358,"end":364},"obj":"Protein"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
testone
{"project":"testone","denotations":[{"id":"T4441","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T4440","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T4439","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T4438","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T4437","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T4436","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T4435","span":{"begin":6,"end":10},"obj":"Protein"},{"id":"T4506","span":{"begin":319,"end":328},"obj":"Positive_regulation"},{"id":"T4505","span":{"begin":308,"end":318},"obj":"Gene_expression"},{"id":"T4504","span":{"begin":289,"end":299},"obj":"Negative_regulation"},{"id":"T4503","span":{"begin":216,"end":226},"obj":"Gene_expression"},{"id":"T4502","span":{"begin":199,"end":207},"obj":"Positive_regulation"},{"id":"T4501","span":{"begin":169,"end":177},"obj":"Positive_regulation"},{"id":"T4500","span":{"begin":55,"end":65},"obj":"Gene_expression"},{"id":"T4499","span":{"begin":38,"end":49},"obj":"Positive_regulation"},{"id":"T4498","span":{"begin":28,"end":35},"obj":"Positive_regulation"}],"relations":[{"id":"R2730","pred":"themeOf","subj":"T4436","obj":"T4500"},{"id":"R2731","pred":"themeOf","subj":"T4437","obj":"T4503"},{"id":"R2732","pred":"themeOf","subj":"T4438","obj":"T4505"},{"id":"R2733","pred":"causeOf","subj":"T4439","obj":"T4506"},{"id":"R2734","pred":"causeOf","subj":"T4439","obj":"T4504"},{"id":"R2735","pred":"causeOf","subj":"T4440","obj":"T4506"},{"id":"R2736","pred":"causeOf","subj":"T4440","obj":"T4504"},{"id":"R2737","pred":"causeOf","subj":"T4441","obj":"T4506"},{"id":"R2738","pred":"causeOf","subj":"T4441","obj":"T4504"},{"id":"R2774","pred":"themeOf","subj":"T4499","obj":"T4498"},{"id":"R2775","pred":"themeOf","subj":"T4500","obj":"T4499"},{"id":"R2776","pred":"themeOf","subj":"T4502","obj":"T4501"},{"id":"R2777","pred":"themeOf","subj":"T4503","obj":"T4502"},{"id":"R2778","pred":"themeOf","subj":"T4505","obj":"T4504"},{"id":"R2779","pred":"themeOf","subj":"T4505","obj":"T4506"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}
test3
{"project":"test3","denotations":[{"id":"T4656","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T4655","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T4654","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T4653","span":{"begin":319,"end":328},"obj":"Positive_regulation"},{"id":"T4652","span":{"begin":308,"end":318},"obj":"Gene_expression"},{"id":"T4651","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T4650","span":{"begin":289,"end":299},"obj":"Negative_regulation"},{"id":"T4649","span":{"begin":216,"end":226},"obj":"Gene_expression"},{"id":"T4648","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T4647","span":{"begin":199,"end":207},"obj":"Positive_regulation"},{"id":"T4646","span":{"begin":169,"end":177},"obj":"Positive_regulation"},{"id":"T4645","span":{"begin":55,"end":65},"obj":"Gene_expression"},{"id":"T4644","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T4643","span":{"begin":28,"end":35},"obj":"Positive_regulation"},{"id":"T4562","span":{"begin":371,"end":377},"obj":"Protein"},{"id":"T4561","span":{"begin":358,"end":364},"obj":"Protein"},{"id":"T4560","span":{"begin":334,"end":340},"obj":"Protein"},{"id":"T4559","span":{"begin":303,"end":307},"obj":"Protein"},{"id":"T4558","span":{"begin":211,"end":215},"obj":"Protein"},{"id":"T4557","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T4556","span":{"begin":6,"end":10},"obj":"Protein"}],"relations":[{"id":"R2811","pred":"themeOf","subj":"T4644","obj":"T4645"},{"id":"R2812","pred":"themeOf","subj":"T4645","obj":"T4643"},{"id":"R2813","pred":"themeOf","subj":"T4647","obj":"T4646"},{"id":"R2814","pred":"themeOf","subj":"T4648","obj":"T4649"},{"id":"R2815","pred":"themeOf","subj":"T4649","obj":"T4647"},{"id":"R2816","pred":"themeOf","subj":"T4650","obj":"T4653"},{"id":"R2817","pred":"themeOf","subj":"T4651","obj":"T4652"},{"id":"R2818","pred":"themeOf","subj":"T4652","obj":"T4650"},{"id":"R2819","pred":"themeOf","subj":"T4652","obj":"T4653"},{"id":"R2820","pred":"causeOf","subj":"T4654","obj":"T4653"},{"id":"R2821","pred":"causeOf","subj":"T4654","obj":"T4650"},{"id":"R2822","pred":"causeOf","subj":"T4655","obj":"T4653"},{"id":"R2823","pred":"causeOf","subj":"T4655","obj":"T4650"},{"id":"R2824","pred":"causeOf","subj":"T4656","obj":"T4653"},{"id":"R2825","pred":"causeOf","subj":"T4656","obj":"T4650"}],"text":"(iii) IL-8\nWe found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p \u003c 0.01). A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc. There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail)."}