PMC:1472690 / 0-807
Annnotations
bionlp-st-ge-2016-test-proteins
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T299 | 69-73 | Protein | denotes | IL-6 |
| T300 | 119-124 | Protein | denotes | IL-1β |
| T301 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T302 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T303 | 602-608 | Protein | denotes | TSST-1 |
| T304 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T305 | 692-696 | Protein | denotes | NFAT |
| T306 | 715-721 | Protein | denotes | TSST-1 |
| T307 | 764-769 | Protein | denotes | IL-1β |
| T308 | 771-775 | Protein | denotes | IL-6 |
| T309 | 777-800 | Protein | denotes | tumor necrosis factor α |
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T426 | 69-73 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T427 | 771-775 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T429 | 119-124 | http://www.uniprot.org/uniprot/P01584 | denotes | IL-1β |
| T430 | 764-769 | http://www.uniprot.org/uniprot/P01584 | denotes | IL-1β |
| T433 | 599-606 | http://www.uniprot.org/uniprot/P06886 | denotes | 1 (TSST |
| T434 | 715-721 | http://www.uniprot.org/uniprot/P06886 | denotes | TSST-1 |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T187 | 446-451 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T206 | 125-138 | http://purl.obolibrary.org/obo/GO_0004908 | denotes | IL-1 receptor |
| T207 | 406-414 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
| T208 | 452-473 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | immune cells mediated |
| T209 | 452-473 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | immune cells mediated |
| T210 | 452-473 | http://purl.obolibrary.org/obo/GO_0019724 | denotes | immune cells mediated |
| T211 | 452-473 | http://purl.obolibrary.org/obo/GO_0002228 | denotes | immune cells mediated |
| T212 | 452-473 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | immune cells mediated |
| T213 | 452-473 | http://purl.obolibrary.org/obo/GO_0001909 | denotes | immune cells mediated |
| T214 | 783-791 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
| T215 | 783-791 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
| T216 | 783-791 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
| T217 | 783-791 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T335 | 27-38 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA binding |
| T337 | 31-38 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T342 | 69-73 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T343 | 771-775 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T345 | 125-129 | http://purl.obolibrary.org/obo/GO_0005149 | denotes | IL-1 |
| T347 | 125-138 | http://purl.obolibrary.org/obo/GO_0004908 | denotes | IL-1 receptor |
| T348 | 486-500 | http://purl.obolibrary.org/obo/GO_0001872 | denotes | β-1→3-D-glucan |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T356 | 459-464 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T188 | 0-155 | Sentence | denotes | β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio |
| T189 | 166-176 | Sentence | denotes | Background |
| T190 | 177-287 | Sentence | denotes | β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses. |
| T191 | 288-610 | Sentence | denotes | Employing a comprehensive methodological approach, the aim of our in vitro study was to elucidate novel molecular and cellular mechanisms of human peripheral blood immune cells mediated by a fungal β-1→3-D-glucan, i.e. glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1). |
| T192 | 612-619 | Sentence | denotes | Results |
| T1 | 0-155 | Sentence | denotes | β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio |
| T2 | 157-165 | Sentence | denotes | Abstract |
| T3 | 166-176 | Sentence | denotes | Background |
| T4 | 177-287 | Sentence | denotes | β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses. |
| T5 | 288-610 | Sentence | denotes | Employing a comprehensive methodological approach, the aim of our in vitro study was to elucidate novel molecular and cellular mechanisms of human peripheral blood immune cells mediated by a fungal β-1→3-D-glucan, i.e. glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1). |
| T6 | 612-619 | Sentence | denotes | Results |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T333 | 572-592 | http://purl.bioontology.org/ontology/ICD10/A48.3 | denotes | toxic shock syndrome |
| T334 | 578-583 | http://purl.bioontology.org/ontology/ICD10/R57.9 | denotes | shock |
simple1
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T392 | 69-73 | Protein | denotes | IL-6 |
| T393 | 119-124 | Protein | denotes | IL-1β |
| T394 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T395 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T396 | 602-608 | Protein | denotes | TSST-1 |
| T397 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T398 | 692-696 | Protein | denotes | NFAT |
| T399 | 715-721 | Protein | denotes | TSST-1 |
| T400 | 764-769 | Protein | denotes | IL-1β |
| T401 | 771-775 | Protein | denotes | IL-6 |
| T402 | 777-800 | Protein | denotes | tumor necrosis factor α |
BioNLP16_DUT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T858 | 17-26 | Regulation | denotes | modulates |
| T859 | 31-38 | Binding | denotes | binding |
| T860 | 750-760 | Gene_expression | denotes | production |
| T861 | 631-641 | Positive_regulation | denotes | activation |
| T824 | 69-73 | Protein | denotes | IL-6 |
| T825 | 119-124 | Protein | denotes | IL-1β |
| T826 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T827 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T828 | 602-608 | Protein | denotes | TSST-1 |
| T829 | 771-775 | Protein | denotes | IL-6 |
| T830 | 777-800 | Protein | denotes | tumor necrosis factor α |
| T832 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T833 | 692-696 | Protein | denotes | NFAT |
| T834 | 715-721 | Protein | denotes | TSST-1 |
| T835 | 764-769 | Protein | denotes | IL-1β |
| R210 | T859 | T858 | themeOf | binding,modulates |
| R337 | T824 | T859 | themeOf | IL-6,binding |
| R338 | T829 | T860 | themeOf | IL-6,production |
| R339 | T830 | T860 | themeOf | tumor necrosis factor α,production |
| R341 | T832 | T861 | themeOf | NFinterleukin(IL)-6,activation |
| R342 | T833 | T861 | themeOf | NFAT,activation |
| R343 | T835 | T860 | themeOf | IL-1β,production |
BioNLP16_Messiy
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T484 | 17-26 | Regulation | denotes | modulates |
| T485 | 31-38 | Binding | denotes | binding |
| T487 | 750-760 | Gene_expression | denotes | production |
| T488 | 631-641 | Positive_regulation | denotes | activation |
| T450 | 69-73 | Protein | denotes | IL-6 |
| T451 | 119-124 | Protein | denotes | IL-1β |
| T452 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T453 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T454 | 602-608 | Protein | denotes | TSST-1 |
| T455 | 771-775 | Protein | denotes | IL-6 |
| T456 | 777-800 | Protein | denotes | tumor necrosis factor α |
| T458 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T459 | 692-696 | Protein | denotes | NFAT |
| T460 | 715-721 | Protein | denotes | TSST-1 |
| T461 | 764-769 | Protein | denotes | IL-1β |
| R122 | T485 | T484 | themeOf | binding,modulates |
| R245 | T450 | T485 | themeOf | IL-6,binding |
| R246 | T455 | T487 | themeOf | IL-6,production |
| R247 | T456 | T487 | themeOf | tumor necrosis factor α,production |
| R250 | T458 | T488 | themeOf | NFinterleukin(IL)-6,activation |
| R251 | T459 | T488 | themeOf | NFAT,activation |
| R252 | T461 | T487 | themeOf | IL-1β,production |
DLUT931
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T605 | 17-26 | Positive_regulation | denotes | modulates |
| T604 | 31-38 | Binding | denotes | binding |
| T606 | 631-641 | Positive_regulation | denotes | activation |
| T607 | 750-760 | Gene_expression | denotes | production |
| T570 | 69-73 | Protein | denotes | IL-6 |
| T571 | 119-124 | Protein | denotes | IL-1β |
| T572 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T573 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T574 | 602-608 | Protein | denotes | TSST-1 |
| T575 | 771-775 | Protein | denotes | IL-6 |
| T576 | 777-800 | Protein | denotes | tumor necrosis factor α |
| T578 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T579 | 692-696 | Protein | denotes | NFAT |
| T580 | 715-721 | Protein | denotes | TSST-1 |
| T581 | 764-769 | Protein | denotes | IL-1β |
| R141 | T604 | T605 | themeOf | binding,modulates |
| R297 | T570 | T604 | themeOf | IL-6,binding |
| R298 | T575 | T607 | themeOf | IL-6,production |
| R299 | T576 | T607 | themeOf | tumor necrosis factor α,production |
| R301 | T579 | T606 | themeOf | NFAT,activation |
| R302 | T581 | T607 | themeOf | IL-1β,production |
bionlp-st-ge-2016-test-ihmc
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T761 | 507-513 | Entity | denotes | glucan |
| T765 | 692-722 | Protein | denotes | NFAT similar to LPS or TSST-1, |
| T767 | 715-721 | Protein | denotes | TSST-1 |
| T773 | 777-800 | Protein | denotes | tumor necrosis factor α |
| T774 | 572-609 | Protein | denotes | toxic shock syndrome toxin 1 (TSST-1) |
| T776 | 69-155 | Protein | denotes | IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio |
| T777 | 452-500 | Entity | denotes | immune cells mediated by a fungal β-1→3-D-glucan |
| T778 | 602-608 | Protein | denotes | TSST-1 |
| T780 | 88-105 | Entity | denotes | anti-inflammatory |
| T790 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T792 | 541-568 | Entity | denotes | of lipopolysaccharide (LPS) |
| T800 | 708-711 | Entity | denotes | LPS |
| T804 | 564-567 | Entity | denotes | LPS |
| T731 | 771-775 | Protein | denotes | IL-6 |
| T739 | 764-769 | Protein | denotes | IL-1β |
| T740 | 507-609 | Entity | denotes | glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1) |
| T741 | 119-129 | Protein | denotes | IL-1β/IL-1 |
| T742 | 139-149 | Entity | denotes | antagonist |
| T745 | 130-138 | Protein | denotes | receptor |
| T756 | 125-129 | Protein | denotes | IL-1 |
| T760 | 119-129 | Protein | denotes | IL-1β/IL-1 |
bionlp-st-ge-2016-test-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T507 | 42-64 | Protein | denotes | nuclear factors κB, AT |
| T508 | 69-73 | Protein | denotes | IL-6 |
| T509 | 119-138 | Protein | denotes | IL-1β/IL-1 receptor |
| T510 | 31-38 | Binding | denotes | binding |
| T511 | 31-38 | Binding | denotes | binding |
| T512 | 17-26 | Regulation | denotes | modulates |
| T513 | 17-26 | Regulation | denotes | modulates |
| T514 | 645-666 | Protein | denotes | nuclear factor (NF)κB |
| T518 | 771-775 | Protein | denotes | IL-6 |
| T519 | 777-800 | Protein | denotes | tumor necrosis factor α |
| T521 | 631-641 | Positive_regulation | denotes | activation |
| T522 | 631-641 | Positive_regulation | denotes | activation |
| T523 | 631-641 | Positive_regulation | denotes | activation |
| T515 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T516 | 692-696 | Protein | denotes | NFAT |
| T517 | 764-769 | Protein | denotes | IL-1β |
| T524 | 750-760 | Gene_expression | denotes | production |
| T525 | 750-760 | Gene_expression | denotes | production |
| T526 | 750-760 | Gene_expression | denotes | production |
| T527 | 750-760 | Gene_expression | denotes | production |
| R259 | T507 | T510 | themeOf | "nuclear factors κB, AT",binding |
| R260 | T508 | T511 | themeOf | IL-6,binding |
| R261 | T510 | T512 | themeOf | binding,modulates |
| R262 | T511 | T513 | themeOf | binding,modulates |
| R263 | T514 | T521 | themeOf | nuclear factor (NF)κB,activation |
| R264 | T515 | T522 | themeOf | NFinterleukin(IL)-6,activation |
| R265 | T516 | T523 | themeOf | NFAT,activation |
| R266 | T517 | T524 | themeOf | IL-1β,production |
| R267 | T518 | T525 | themeOf | IL-6,production |
| R268 | T519 | T526 | themeOf | tumor necrosis factor α,production |
testone
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T36 | 119-124 | Protein | denotes | IL-1β |
| T37 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T38 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T39 | 602-608 | Protein | denotes | TSST-1 |
| T40 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T41 | 692-696 | Protein | denotes | NFAT |
| T42 | 715-721 | Protein | denotes | TSST-1 |
| T43 | 764-769 | Protein | denotes | IL-1β |
| T44 | 771-775 | Protein | denotes | IL-6 |
| T45 | 777-800 | Protein | denotes | tumor necrosis factor α |
| T69 | 31-38 | Binding | denotes | binding |
| T70 | 139-149 | Negative_regulation | denotes | antagonist |
| T71 | 750-760 | Gene_expression | denotes | production |
| T35 | 69-73 | Protein | denotes | IL-6 |
| R1 | T39 | T38 | equivalentTo | TSST-1,toxic shock syndrome toxin 1 |
| R2 | T43 | T71 | themeOf | IL-1β,production |
| R3 | T44 | T71 | themeOf | IL-6,production |
| R55 | T35 | T69 | themeOf | IL-6,binding |
| R4 | T45 | T71 | themeOf | tumor necrosis factor α,production |
test3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T100 | 602-608 | Protein | denotes | TSST-1 |
| T101 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T102 | 692-696 | Protein | denotes | NFAT |
| T103 | 715-721 | Protein | denotes | TSST-1 |
| T104 | 764-769 | Protein | denotes | IL-1β |
| T96 | 69-73 | Protein | denotes | IL-6 |
| T97 | 119-124 | Protein | denotes | IL-1β |
| T98 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T99 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T105 | 771-775 | Protein | denotes | IL-6 |
| T106 | 777-800 | Protein | denotes | tumor necrosis factor α |
| T130 | 31-38 | Binding | denotes | binding |
| T131 | 69-73 | Protein | denotes | IL-6 |
| T132 | 74-81 | Positive_regulation | denotes | leading |
| T133 | 119-124 | Protein | denotes | IL-1β |
| T134 | 125-149 | Protein | denotes | IL-1 receptor antagonist |
| T135 | 572-600 | Protein | denotes | toxic shock syndrome toxin 1 |
| T136 | 602-608 | Protein | denotes | TSST-1 |
| T137 | 631-641 | Positive_regulation | denotes | activation |
| T138 | 668-687 | Protein | denotes | NFinterleukin(IL)-6 |
| T139 | 692-696 | Protein | denotes | NFAT |
| T140 | 715-721 | Protein | denotes | TSST-1 |
| T141 | 750-760 | Gene_expression | denotes | production |
| T142 | 764-769 | Protein | denotes | IL-1β |
| T143 | 771-775 | Protein | denotes | IL-6 |
| T144 | 777-800 | Protein | denotes | tumor necrosis factor α |
| R41 | T136 | T135 | equivalentTo | TSST-1,toxic shock syndrome toxin 1 |
| R42 | T138 | T137 | themeOf | NFinterleukin(IL)-6,activation |
| R43 | T139 | T137 | themeOf | NFAT,activation |
| R44 | T140 | T137 | themeOf | TSST-1,activation |
| R46 | T142 | T141 | themeOf | IL-1β,production |
| R47 | T143 | T141 | themeOf | IL-6,production |
| R48 | T144 | T141 | themeOf | tumor necrosis factor α,production |
| R40 | T131 | T130 | themeOf | IL-6,binding |