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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T26233 28056-28064 VB denotes depicted
T26232 28052-28055 VB denotes are
T26231 28046-28051 NN denotes sites
T26230 28038-28045 NN denotes binding
T26229 28031-28037 NN denotes factor
T26228 28017-28030 NN denotes transcription
T26227 28006-28016 JJ denotes regulatory
T26226 28004-28005 -RRB- denotes )
T26225 28000-28004 JJ denotes gray
T26224 27999-28000 -LRB- denotes (
T26223 27988-27998 RB denotes negatively
T26222 27984-27987 CC denotes and
T26221 27982-27983 -RRB- denotes )
T26220 27977-27982 JJ denotes black
T26219 27976-27977 -LRB- denotes (
T26218 27965-27975 RB denotes positively
T26217 27963-27964 -COMMA- denotes ,
T26216 27962-27963 -RRB- denotes )
T26215 27957-27962 VB denotes boxed
T26214 27956-27957 -LRB- denotes (
T26213 27946-27955 VB denotes described
T26212 27940-27945 RB denotes newly
T26211 27936-27939 CC denotes and
T26210 27934-27935 -RRB- denotes ]
T26209 27929-27934 CD denotes 30-33
T26208 27928-27929 -LRB- denotes [
T26207 27926-27927 -RRB- denotes )
T26206 27921-27926 NN denotes LRE-1
T26205 27920-27921 -LRB- denotes (
T26204 27909-27919 RB denotes previously
T26203 27906-27908 IN denotes of
T26202 27896-27905 NN denotes locations
T26201 27887-27895 JJ denotes Relative
T26200 27877-27885 NN denotes promoter
T26199 27870-27876 NN denotes IL-1RA
T26198 27866-27869 DT denotes the
T26197 27863-27865 IN denotes of
T26196 27856-27862 NN denotes strand
T26195 27850-27855 NN denotes sense
T26194 27846-27849 DT denotes the
T26193 27843-27845 IN denotes of
T26192 27835-27842 NN denotes Cartoon
T25791 23686-23687 -RRB- denotes )
T25790 23682-23686 CD denotes 0.01
T25789 23680-23681 SYM denotes <
T25788 23678-23679 NN denotes p
T25787 23676-23677 SYM denotes =
T25786 23673-23675 SYM denotes **
T25785 23671-23672 -COLON- denotes ;
T25784 23667-23671 CD denotes 0.05
T25783 23665-23666 SYM denotes <
T25782 23663-23664 NN denotes p
T25781 23661-23662 SYM denotes =
T25780 23659-23660 SYM denotes *
T25779 23658-23659 -LRB- denotes (
T25778 23655-23657 NN denotes GP
T25777 23652-23654 TO denotes to
T25776 23643-23651 VB denotes compared
T25775 23638-23642 WRB denotes when
T25774 23634-23637 NN denotes CyA
T25773 23631-23633 CC denotes or
T25772 23626-23630 NN denotes CAPE
T25771 23624-23625 -COMMA- denotes ,
T25770 23621-23624 NN denotes CHX
T25769 23616-23620 IN denotes with
T25768 23606-23615 NN denotes treatment
T25767 23596-23605 VB denotes following
T25766 23591-23595 NN denotes PBMC
T25765 23585-23590 JJ denotes human
T25764 23582-23584 IN denotes by
T25763 23575-23581 NN denotes IL-1RA
T25762 23572-23574 IN denotes of
T25761 23561-23571 NN denotes production
T25760 23557-23560 DT denotes the
T25759 23549-23556 VB denotes reduced
T25758 23535-23548 RB denotes significantly
T25757 23528-23534 NN denotes NFIL-6
T25756 23524-23527 CC denotes and
T25755 23519-23523 NN denotes NFAT
T25754 23517-23518 -COMMA- denotes ,
T25753 23513-23517 NN denotes NFκB
T25752 23510-23512 IN denotes of
T25751 23499-23509 NN denotes Inhibition
T25750 23497-23498 -COMMA- denotes ,
T25749 23496-23497 NN denotes C
T25748 23493-23494 -RRB- denotes )
T25747 23492-23493 CD denotes 4
T25746 23490-23491 SYM denotes =
T25745 23488-23489 NN denotes n
T25744 23486-23487 -COMMA- denotes ,
T25743 23483-23486 NN denotes gel
T25742 23468-23482 JJ denotes representative
T25741 23467-23468 -LRB- denotes (
T25740 23459-23466 NN denotes control
T25739 23446-23458 NN denotes housekeeping
T25738 23443-23445 IN denotes as
T25737 23438-23442 VB denotes used
T25736 23435-23437 VB denotes is
T25735 23429-23434 NN denotes GAPDH
T25734 23425-23427 NN denotes GP
T25733 23422-23424 TO denotes to
T25732 23413-23421 VB denotes compared
T25731 23409-23412 NN denotes CyA
T25730 23406-23408 CC denotes or
T25729 23401-23405 NN denotes CAPE
T25728 23399-23400 -COMMA- denotes ,
T25727 23396-23399 NN denotes CHX
T25726 23386-23395 VB denotes following
T25725 23381-23385 NN denotes mRNA
T25724 23374-23380 NN denotes IL-1RA
T25723 23364-23373 VB denotes decreased
T25722 23361-23363 IN denotes in
T25721 23352-23360 VB denotes resulted
T25720 23345-23351 NN denotes NFIL-6
T25719 23341-23344 CC denotes and
T25718 23336-23340 NN denotes NFAT
T25717 23334-23335 -COMMA- denotes ,
T25716 23330-23334 NN denotes NFκB
T25715 23327-23329 IN denotes of
T25714 23316-23326 NN denotes Inhibition
T25713 23314-23315 -COMMA- denotes ,
T25712 23313-23314 NN denotes B
T25711 23310-23311 -RRB- denotes )
T25710 23309-23310 CD denotes 4
T25709 23307-23308 SYM denotes =
T25708 23305-23306 NN denotes n
T25707 23304-23305 -LRB- denotes (
T25706 23300-23303 NN denotes SEM
T25705 23298-23299 NN denotes ±
T25704 23293-23297 JJ denotes mean
T25703 23290-23292 IN denotes as
T25702 23284-23289 VB denotes shown
T25701 23280-23283 VB denotes are
T25700 23275-23279 NN denotes Data
T25699 23272-23273 -RRB- denotes )
T25698 23268-23272 CD denotes 0.05
T25697 23266-23267 SYM denotes <
T25696 23264-23265 NN denotes p
T25695 23262-23263 SYM denotes =
T25694 23260-23261 SYM denotes *
T25693 23259-23260 -LRB- denotes (
T25692 23249-23258 VB denotes displayed
T25691 23246-23248 VB denotes is
T25690 23243-23245 NN denotes GP
T25689 23240-23242 TO denotes to
T25688 23231-23239 VB denotes compared
T25687 23226-23230 WRB denotes when
T25686 23215-23225 NN denotes inhibition
T25685 23205-23214 VB denotes following
T25684 23197-23204 NN denotes binding
T25683 23194-23196 IN denotes in
T25682 23185-23193 NN denotes decrease
T25681 23183-23184 DT denotes a
T25680 23173-23182 VB denotes depicting
T25679 23171-23172 -COMMA- denotes ,
T25678 23167-23171 NN denotes site
T25677 23158-23166 NN denotes NFATP2/3
T25676 23154-23157 DT denotes the
T25675 23150-23153 IN denotes for
T25674 23142-23149 NN denotes summary
T25673 23132-23141 JJ denotes graphical
T25672 23130-23131 DT denotes a
T25671 23127-23129 IN denotes as
T25670 23122-23126 RB denotes well
T25669 23119-23121 RB denotes as
T25668 23117-23118 -RRB- denotes )
T25667 23112-23117 NN denotes water
T25666 23110-23111 -COLON- denotes :
T25665 23109-23110 CD denotes 8
T25664 23104-23108 NN denotes lane
T25663 23102-23103 -COMMA- denotes ,
T25662 23097-23102 NN denotes oligo
T25661 23088-23096 NN denotes NFATP2/3
T25660 23078-23087 JJ denotes unlabeled
T25659 23076-23077 CC denotes +
T25658 23073-23075 NN denotes GP
T25657 23071-23072 -COLON- denotes :
T25656 23070-23071 CD denotes 7
T25655 23065-23069 NN denotes lane
T25654 23063-23064 -COMMA- denotes ,
T25653 23060-23063 NN denotes CHX
T25652 23058-23059 SYM denotes +
T25651 23055-23057 NN denotes GP
T25650 23053-23054 -COLON- denotes :
T25649 23052-23053 CD denotes 6
T25648 23047-23051 NN denotes lane
T25647 23045-23046 -COMMA- denotes ,
T25646 23042-23045 NN denotes CyA
T25645 23040-23041 SYM denotes +
T25644 23037-23039 NN denotes GP
T25643 23035-23036 SYM denotes :
T25642 23034-23035 CD denotes 5
T25641 23029-23033 NN denotes lane
T25640 23027-23028 -COMMA- denotes ,
T25639 23023-23027 NN denotes CAPE
T25638 23021-23022 SYM denotes +
T25637 23018-23020 NN denotes GP
T25636 23016-23017 -COLON- denotes :
T25635 23015-23016 CD denotes 4
T25634 23010-23014 NN denotes lane
T25633 23008-23009 -COMMA- denotes ,
T25632 23003-23008 NN denotes oligo
T25631 22994-23002 NN denotes NFATP2/3
T25630 22986-22993 VB denotes mutated
T25629 22976-22985 JJ denotes unlabeled
T25628 22974-22975 CC denotes +
T25627 22971-22973 NN denotes GP
T25626 22969-22970 -COLON- denotes :
T25625 22968-22969 CD denotes 3
T25624 22963-22967 NN denotes lane
T25623 22961-22962 -COMMA- denotes ,
T25622 22959-22961 NN denotes GP
T25621 22957-22958 -COLON- denotes :
T25620 22956-22957 CD denotes 2
T25619 22951-22955 NN denotes lane
T25618 22949-22950 -COMMA- denotes ,
T25617 22942-22949 NN denotes control
T25616 22940-22941 -COLON- denotes :
T25615 22939-22940 CD denotes 1
T25614 22934-22938 NN denotes lane
T25613 22933-22934 -LRB- denotes (
T25612 22919-22932 NN denotes autoradiogram
T25611 22904-22918 JJ denotes representative
T25610 22902-22903 DT denotes A
T25609 22900-22901 -COMMA- denotes ,
T25608 22899-22900 DT denotes A
T25607 22889-22897 NN denotes promoter
T25606 22882-22888 NN denotes IL-1RA
T25605 22878-22881 DT denotes the
T25604 22875-22877 TO denotes to
T25603 22867-22874 NN denotes binding
T25602 22863-22866 NN denotes DNA
T25601 22856-22862 NN denotes NFIL-6
T25600 22852-22855 CC denotes and
T25599 22847-22851 NN denotes NFAT
T25598 22845-22846 -COMMA- denotes ,
T25597 22841-22845 NN denotes NFκB
T25596 22830-22840 JJ denotes GP-induced
T25595 22827-22829 IN denotes of
T25594 22816-22826 NN denotes Inhibition
T25803 23724-23725 -RRB- denotes )
T25802 23723-23724 CD denotes 3
T25801 23721-23722 SYM denotes =
T25800 23719-23720 NN denotes n
T25799 23718-23719 -LRB- denotes (
T25798 23714-23717 NN denotes SEM
T25797 23712-23713 NN denotes ±
T25796 23707-23711 JJ denotes mean
T25795 23704-23706 IN denotes as
T25794 23698-23703 VB denotes shown
T25793 23694-23697 VB denotes are
T25792 23689-23693 NN denotes Data
T24436 19654-19655 -RRB- denotes )
T24435 19648-19654 NN denotes TSST-1
T24434 19646-19647 SYM denotes +
T24433 19643-19645 NN denotes GP
T24432 19641-19642 -COLON- denotes :
T24431 19640-19641 CD denotes 7
T24430 19635-19639 NN denotes lane
T24429 19633-19634 -COLON- denotes ;
T24428 19630-19633 NN denotes LPS
T24427 19628-19629 CC denotes +
T24426 19625-19627 NN denotes GP
T24425 19623-19624 -COLON- denotes :
T24424 19622-19623 CD denotes 6
T24423 19617-19621 NN denotes lane
T24422 19615-19616 -COMMA- denotes ,
T24421 19609-19615 NN denotes TSST-1
T24420 19607-19608 -COLON- denotes :
T24419 19606-19607 CD denotes 5
T24418 19601-19605 NN denotes lane
T24417 19599-19600 -COLON- denotes ;
T24416 19596-19599 NN denotes LPS
T24415 19594-19595 -COLON- denotes :
T24414 19593-19594 CD denotes 4
T24413 19588-19592 NN denotes lane
T24412 19586-19587 -COLON- denotes ;
T24411 19584-19586 NN denotes GP
T24410 19582-19583 -COLON- denotes :
T24409 19581-19582 CD denotes 3
T24408 19576-19580 NN denotes lane
T24407 19574-19575 -COLON- denotes ;
T24406 19567-19574 NN denotes control
T24405 19560-19566 NN denotes medium
T24404 19558-19559 -COLON- denotes :
T24403 19557-19558 CD denotes 2
T24402 19552-19556 NN denotes lane
T24401 19550-19551 -COLON- denotes ;
T24400 19545-19550 NN denotes water
T24399 19543-19544 -COLON- denotes :
T24398 19542-19543 CD denotes 1
T24397 19537-19541 NN denotes lane
T24396 19536-19537 -LRB- denotes (
T24395 19530-19535 NN denotes panel
T24394 19524-19529 JJ denotes lower
T24393 19520-19523 DT denotes the
T24392 19517-19519 IN denotes in
T24391 19511-19516 VB denotes shown
T24390 19508-19510 VB denotes is
T24389 19497-19507 NN denotes experiment
T24388 19482-19496 JJ denotes representative
T24387 19480-19481 DT denotes a
T24386 19477-19479 IN denotes of
T24385 19463-19476 NN denotes autoradiogram
T24384 19460-19462 DT denotes An
T24383 19457-19458 -RRB- denotes )
T24382 19456-19457 CD denotes 6
T24381 19454-19455 JJ denotes =
T24380 19452-19453 NN denotes n
T23988 18870-18871 -RRB- denotes )
T23987 18863-18870 NN denotes methods
T23986 18859-18862 VB denotes see
T23985 18858-18859 -LRB- denotes (
T23984 18853-18857 NN denotes EMSA
T23983 18850-18852 IN denotes by
T23982 18841-18849 VB denotes assessed
T23981 18837-18840 VB denotes was
T23980 18829-18836 NN denotes binding
T23979 18825-18828 NN denotes DNA
T23978 18822-18823 -RRB- denotes )
T23977 18821-18822 CD denotes 6
T23976 18819-18820 JJ denotes =
T23975 18817-18818 NN denotes n
T23974 18816-18817 -LRB- denotes (
T23973 18812-18815 NN denotes SEM
T23972 18810-18811 CC denotes ±
T23971 18808-18809 CD denotes 1
T23970 18805-18807 TO denotes to
T23969 18799-18804 JJ denotes equal
T23968 18795-18798 VB denotes set
T23967 18790-18794 VB denotes were
T23966 18783-18789 NN denotes levels
T23965 18775-18782 NN denotes control
T23964 18768-18774 NN denotes Medium
T23963 18765-18766 -RRB- denotes )
T23962 18761-18765 CD denotes 0.01
T23961 18759-18760 SYM denotes <
T23960 18757-18758 NN denotes p
T23959 18755-18756 SYM denotes =
T23958 18752-18754 SYM denotes **
T23957 18750-18751 -COLON- denotes ;
T23956 18746-18750 CD denotes 0.05
T23955 18744-18745 SYM denotes <
T23954 18742-18743 NN denotes p
T23953 18740-18741 SYM denotes =
T23952 18738-18739 SYM denotes *
T23951 18737-18738 -LRB- denotes (
T23950 18724-18736 RB denotes respectively
T23949 18722-18723 -COMMA- denotes ,
T23948 18717-18722 NN denotes calc.
T23947 18707-18716 NN denotes GP/TSST-1
T23946 18704-18706 CC denotes or
T23945 18698-18703 NN denotes calc.
T23944 18691-18697 NN denotes GP/LPS
T23943 18689-18690 -COMMA- denotes ,
T23942 18687-18689 NN denotes GP
T23941 18685-18686 -COMMA- denotes ,
T23940 18679-18685 NN denotes TSST-1
T23939 18677-18678 -COMMA- denotes ,
T23938 18674-18677 NN denotes LPS
T23937 18671-18673 TO denotes to
T23936 18662-18670 VB denotes compared
T23935 18657-18661 WRB denotes when
T23934 18655-18656 -COMMA- denotes ,
T23933 18649-18655 NN denotes TSST-1
T23932 18647-18648 SYM denotes +
T23931 18644-18646 NN denotes GP
T23930 18640-18643 CC denotes and
T23929 18636-18639 NN denotes LPS
T23928 18634-18635 SYM denotes +
T23927 18631-18633 NN denotes GP
T23926 18627-18630 IN denotes for
T23925 18618-18626 VB denotes enhanced
T23924 18614-18617 VB denotes was
T23923 18606-18613 NN denotes Binding
T23922 18596-18604 NN denotes promoter
T23921 18589-18595 NN denotes IL-1RA
T25041 21430-21432 CD denotes 24
T25040 21426-21429 CC denotes and
T25039 21424-21425 NN denotes h
T25038 21421-21423 CD denotes 18
T25037 21418-21420 IN denotes at
T25036 21412-21417 NN denotes ratio
T25035 21404-21411 VB denotes reduced
T25034 21399-21403 JJ denotes fold
T25033 21392-21398 CD denotes 10–100
T25032 21386-21391 IN denotes about
T25031 21383-21385 DT denotes an
T25030 21380-21382 IN denotes by
T25029 21367-21379 VB denotes demonstrated
T25028 21364-21366 IN denotes as
T25027 21362-21363 -COMMA- denotes ,
T25026 21360-21362 NN denotes GP
T25025 21357-21359 IN denotes of
T25024 21350-21356 NN denotes action
T25023 21332-21349 JJ denotes anti-inflammatory
T25022 21321-21331 JJ denotes pronounced
T25021 21319-21320 DT denotes a
T25020 21310-21318 VB denotes observed
T25019 21307-21309 PRP denotes we
T25018 21300-21306 NN denotes TSST-1
T25017 21298-21299 SYM denotes +
T25016 21295-21297 NN denotes GP
T25015 21292-21294 IN denotes vs
T25014 21286-21291 NN denotes calc.
T25013 21276-21285 NN denotes GP/TSST-1
T25012 21273-21275 CC denotes or
T25011 21266-21272 NN denotes TSST-1
T25010 21263-21265 TO denotes to
T25009 21255-21262 NN denotes respect
T25008 21250-21254 IN denotes With
T25007 21247-21248 NN denotes h
T25006 21244-21246 CD denotes 48
T25005 21239-21243 IN denotes over
T25004 21233-21238 NN denotes ratio
T25003 21220-21232 NN denotes IL-1β/IL-1RA
T25002 21216-21219 DT denotes the
T25001 21213-21215 IN denotes in
T25000 21201-21212 NN denotes alterations
T24999 21189-21200 JJ denotes significant
T24998 21184-21188 VB denotes find
T24997 21180-21183 RB denotes not
T24996 21176-21179 VB denotes did
T24995 21173-21175 PRP denotes we
T24994 21169-21172 NN denotes LPS
T24993 21167-21168 SYM denotes +
T24992 21164-21166 NN denotes GP
T24991 21161-21163 IN denotes vs
T24990 21155-21160 NN denotes calc.
T24989 21148-21154 NN denotes GP/LPS
T24988 21145-21147 CC denotes or
T24987 21141-21144 NN denotes LPS
T24986 21131-21140 VB denotes comparing
T24985 21126-21130 WRB denotes When
T24984 21123-21124 NN denotes h
T24983 21120-21122 CD denotes 24
T24982 21117-21119 TO denotes to
T24981 21114-21116 IN denotes up
T24980 21107-21113 NN denotes IL-1RA
T24979 21102-21106 IN denotes than
T24978 21096-21101 NN denotes IL-1β
T24977 21091-21095 JJ denotes more
T24976 21080-21090 VB denotes generating
T24975 21077-21079 IN denotes in
T24974 21068-21076 VB denotes resulted
T24973 21057-21067 NN denotes treatments
T24972 21053-21056 NN denotes LPS
T24971 21051-21052 SYM denotes +
T24970 21048-21050 NN denotes GP
T24969 21044-21047 CC denotes and
T24968 21040-21043 NN denotes LPS
T24967 21034-21038 NN denotes calc
T24966 21024-21033 NN denotes GP/TSST-1
T24965 21021-21023 CC denotes or
T24964 21014-21020 NN denotes TSST-1
T24963 21012-21013 SYM denotes +
T24962 21009-21011 NN denotes GP
T24961 21007-21008 -COMMA- denotes ,
T24960 21002-21007 NN denotes calc.
T24959 20995-21001 NN denotes GP/LPS
T24958 20993-20994 -COMMA- denotes ,
T24957 20990-20993 NN denotes LPS
T24956 20988-20989 SYM denotes +
T24955 20985-20987 NN denotes GP
T24954 20983-20984 -COMMA- denotes ,
T24953 20977-20983 NN denotes TSST-1
T24952 20975-20976 -COMMA- denotes ,
T24951 20972-20975 NN denotes LPS
T24950 20967-20971 IN denotes with
T24949 20962-20966 NN denotes PBMC
T24948 20956-20961 JJ denotes human
T24947 20953-20955 IN denotes of
T24946 20942-20952 NN denotes incubation
T24945 20932-20941 VB denotes following
T24944 20926-20931 NN denotes ratio
T24943 20913-20925 NN denotes IL-1β/IL-1RA
T24942 20909-20912 DT denotes the
T24941 20906-20908 IN denotes of
T24940 20904-20905 -RRB- denotes )
T24939 20903-20904 NN denotes h
T24938 20900-20902 CD denotes 48
T24937 20899-20900 -LRB- denotes (
T24936 20892-20898 NN denotes course
T24935 20887-20891 NN denotes Time
T24934 20879-20885 NN denotes TSST-1
T24933 20876-20878 TO denotes to
T24932 20867-20875 VB denotes compared
T24931 20862-20866 WRB denotes when
T24930 20855-20861 NN denotes TSST-1
T24929 20853-20854 SYM denotes +
T24928 20850-20852 NN denotes GP
T24927 20840-20849 VB denotes following
T24926 20834-20839 NN denotes ratio
T24925 20821-20833 NN denotes IL-1β/IL-1RA
T24924 20811-20820 VB denotes Decreased
T23920 18585-18588 DT denotes the
T23919 18582-18584 IN denotes in
T23918 18577-18581 NN denotes site
T23917 18571-18576 NN denotes NFκB3
T23916 18567-18570 JJ denotes new
T23915 18565-18566 DT denotes a
T23914 18562-18564 TO denotes to
T23913 18554-18561 NN denotes binding
T23912 18539-18553 JJ denotes TSST-1-induced
T23911 18535-18538 CC denotes and
T23910 18530-18534 NN denotes LPS-
T23909 18520-18529 VB denotes modulated
T23908 18517-18519 NN denotes GP
T24379 19451-19452 -LRB- denotes (
T24378 19447-19450 NN denotes SEM
T24377 19445-19446 CC denotes ±
T24376 19443-19444 CD denotes 1
T24375 19440-19442 TO denotes to
T24374 19434-19439 JJ denotes equal
T24373 19430-19433 VB denotes set
T24372 19425-19429 VB denotes were
T24371 19418-19424 NN denotes levels
T24370 19410-19417 NN denotes control
T24369 19403-19409 NN denotes Medium
T24368 19396-19401 VB denotes added
T24367 19392-19395 VB denotes are
T24366 19386-19391 NN denotes calc.
T24365 19376-19385 NN denotes GP/TSST-1
T24364 19372-19375 CC denotes and
T24363 19366-19371 NN denotes calc.
T24362 19359-19365 NN denotes GP/LPS
T24361 19355-19358 IN denotes for
T24360 19348-19354 NN denotes values
T24359 19336-19347 JJ denotes theoretical
T24358 19332-19335 DT denotes the
T24357 19322-19331 VB denotes depicting
T24356 19317-19321 NN denotes Bars
T24355 19307-19315 NN denotes promoter
T24354 19300-19306 NN denotes IL-1RA
T24353 19296-19299 DT denotes the
T24352 19293-19295 IN denotes in
T24351 19288-19292 NN denotes site
T24350 19284-19287 DT denotes the
T24349 19281-19283 TO denotes to
T24348 19272-19280 NN denotes activity
T24347 19264-19271 NN denotes binding
T24346 19255-19263 NN denotes NFAT-DNA
T24345 19246-19254 JJ denotes elevated
T24344 19242-19245 DT denotes the
T24343 19239-19241 IN denotes of
T24342 19224-19238 NN denotes representation
T24341 19214-19223 NNP denotes Schematic
T24340 19208-19213 NNP denotes 37°C.
T24339 19205-19207 IN denotes at
T24338 19203-19204 NN denotes h
T24337 19201-19202 CD denotes 1
T24336 19197-19200 IN denotes for
T24335 19193-19196 NN denotes LPS
T24334 19191-19192 SYM denotes +
T24333 19188-19190 NN denotes GP
T24332 19184-19187 CC denotes and
T24331 19177-19183 NN denotes TSST-1
T24330 19175-19176 SYM denotes +
T24329 19172-19174 NN denotes GP
T24328 19170-19171 -COMMA- denotes ,
T24327 19168-19170 NN denotes GP
T24326 19166-19167 -COMMA- denotes ,
T24325 19160-19166 NN denotes TSST-1
T24324 19158-19159 -COMMA- denotes ,
T24323 19155-19158 NN denotes LPS
T24322 19153-19154 -COMMA- denotes ,
T24321 19146-19153 NN denotes control
T24320 19139-19145 NN denotes medium
T24319 19134-19138 IN denotes with
T24318 19124-19133 VB denotes incubated
T24317 19119-19123 VB denotes were
T24316 19114-19118 NN denotes PBMC
T24315 19108-19113 JJ denotes Human
T24314 19105-19106 -RRB- denotes )
T24313 19101-19105 CD denotes 0.05
T24300 19057-19063 JJ denotes latter
T24299 19053-19056 DT denotes the
T24298 19050-19052 IN denotes in
T24297 19048-19049 -COMMA- denotes ,
T24296 19045-19048 CC denotes and
T24295 19042-19044 NN denotes GP
T24294 19039-19041 TO denotes to
T24293 19030-19038 VB denotes compared
T24292 19025-19029 WRB denotes when
T24291 19023-19024 -COMMA- denotes ,
T24290 19017-19023 NN denotes TSST-1
T24289 19015-19016 SYM denotes +
T24288 19012-19014 NN denotes GP
T24287 19008-19011 CC denotes and
T24286 19004-19007 NN denotes LPS
T24285 19002-19003 SYM denotes +
T24284 18999-19001 NN denotes GP
T24283 18995-18998 IN denotes for
T24282 18982-18994 VB denotes up-regulated
T24281 18978-18981 VB denotes was
T24280 18970-18977 NN denotes Binding
T24279 18960-18968 NN denotes promoter
T24278 18953-18959 NN denotes IL-1RA
T24277 18949-18952 DT denotes the
T24276 18946-18948 IN denotes in
T24275 18941-18945 NN denotes site
T24274 18932-18940 NN denotes NFATP2/3
T24273 18928-18931 JJ denotes new
T24272 18926-18927 DT denotes a
T24271 18923-18925 TO denotes to
T24270 18915-18922 NN denotes binding
T24269 18911-18914 NN denotes DNA
T24268 18896-18910 JJ denotes TSST-1-induced
T24267 18886-18895 VB denotes modulated
T24266 18883-18885 NN denotes GP
T24312 19099-19100 SYM denotes <
T24311 19097-19098 NN denotes p
T24310 19095-19096 SYM denotes =
T24309 19093-19094 SYM denotes *
T24308 19092-19093 -LRB- denotes (
T24307 19085-19091 NN denotes TSST-1
T24306 19081-19084 CC denotes and
T24305 19078-19080 NN denotes GP
T24304 19073-19077 CC denotes both
T24303 19070-19072 TO denotes to
T24302 19068-19069 -COMMA- denotes ,
T24301 19064-19068 NN denotes case
T23284 13104-13110 NN denotes IL-1RA
T23283 13097-13103 JJ denotes higher
T23282 13095-13096 DT denotes a
T23281 13090-13094 FW denotes i.e.
T23280 13088-13089 -COMMA- denotes ,
T23279 13082-13088 NN denotes effect
T23278 13070-13081 JJ denotes synergistic
T23277 13068-13069 DT denotes a
T23276 13065-13067 TO denotes to
T23275 13061-13064 VB denotes led
T23274 13054-13060 NN denotes TSST-1
T23273 13052-13053 SYM denotes +
T23272 13049-13051 NN denotes GP
T23271 13044-13048 IN denotes with
T23270 13039-13043 NN denotes PBMC
T23269 13036-13038 IN denotes of
T23268 13026-13035 NN denotes treatment
T23267 13013-13025 JJ denotes simultaneous
T23266 13011-13012 DT denotes a
T23265 13009-13010 NN denotes h
T23264 13006-13008 CD denotes 48
T23263 13002-13005 CC denotes and
T23262 13000-13001 NN denotes h
T23261 12997-12999 CD denotes 18
T23260 12989-12996 IN denotes Between
T23259 12984-12987 NN denotes LPS
T23258 12982-12983 SYM denotes +
T23257 12979-12981 NN denotes GP
T23256 12975-12978 CC denotes and
T23255 12971-12974 NN denotes LPS
T23254 12968-12970 NN denotes ng
T23253 12964-12967 CD denotes 250
T23252 12962-12963 -COMMA- denotes ,
T23251 12956-12962 NN denotes TSST-1
T23250 12954-12955 SYM denotes +
T23249 12951-12953 NN denotes GP
T23248 12949-12950 -COMMA- denotes ,
T23247 12943-12949 NN denotes TSST-1
T23246 12940-12942 NN denotes ng
T23245 12936-12939 CD denotes 250
T23244 12934-12935 -COMMA- denotes ,
T23243 12932-12934 NN denotes GP
T23242 12929-12931 NN denotes μg
T23241 12925-12928 CD denotes 100
T23240 12923-12924 -COMMA- denotes ,
T23239 12916-12923 NN denotes control
T23238 12909-12915 NN denotes medium
T23237 12904-12908 IN denotes with
T23236 12894-12903 VB denotes incubated
T23235 12889-12893 NN denotes PBMC
T23234 12883-12888 JJ denotes human
T23233 12880-12882 IN denotes by
T23232 12878-12879 -RRB- denotes )
T23231 12873-12878 NN denotes pg/ml
T23230 12872-12873 -LRB- denotes (
T23229 12861-12871 NN denotes production
T23228 12854-12860 NN denotes IL-1RA
T23227 12851-12853 IN denotes of
T23226 12849-12850 -RRB- denotes )
T23225 12848-12849 NN denotes h
T23224 12845-12847 CD denotes 48
T23223 12844-12845 -LRB- denotes (
T23222 12837-12843 NN denotes course
T23221 12832-12836 NN denotes Time
T23220 12824-12830 NN denotes TSST-1
T23219 12821-12823 TO denotes to
T23218 12812-12820 VB denotes compared
T23217 12807-12811 WRB denotes when
T23216 12805-12806 -RRB- denotes )
T23215 12804-12805 NN denotes h
T23214 12801-12803 CD denotes 48
T23213 12799-12800 IN denotes –
T23212 12797-12798 NN denotes h
T23211 12794-12796 CD denotes 12
T23210 12793-12794 -LRB- denotes (
T23209 12786-12792 NN denotes TSST-1
T23208 12784-12785 SYM denotes +
T23207 12781-12783 NN denotes GP
T23206 12771-12780 VB denotes following
T23205 12759-12770 VB denotes exaggerated
T23204 12755-12758 VB denotes was
T23203 12748-12754 NN denotes IL-1RA
T23202 12746-12747 -COMMA- denotes ,
T23201 12745-12746 NN denotes B
T23200 12742-12743 -RRB- denotes )
T23199 12741-12742 CD denotes 3
T23198 12739-12740 SYM denotes =
T23197 12737-12738 NN denotes n
T23196 12736-12737 -LRB- denotes (
T23195 12732-12735 NN denotes SEM
T23194 12730-12731 NN denotes ±
T23193 12725-12729 JJ denotes mean
T23192 12722-12724 IN denotes as
T23191 12716-12721 VB denotes shown
T23190 12712-12715 VB denotes are
T23189 12708-12711 CC denotes and
T23188 12702-12707 NNP denotes Elisa
T23187 12699-12701 IN denotes by
T23186 12690-12698 VB denotes obtained
T23185 12685-12689 VB denotes were
T23184 12672-12684 NN denotes supernatnant
T23183 12668-12671 DT denotes the
T23182 12665-12667 IN denotes in
T23181 12658-12664 NN denotes levels
T23180 12652-12657 NN denotes IL-1β
T23179 12645-12650 VB denotes shown
T23178 12640-12644 RB denotes also
T23177 12636-12639 VB denotes are
T23176 12630-12635 NN denotes calc.
T23175 12620-12629 NN denotes GP/TSST-1
T23174 12616-12619 CC denotes and
T23173 12610-12615 NN denotes calc.
T23172 12603-12609 NN denotes GP/LPS
T23171 12599-12602 IN denotes for
T23170 12592-12598 NN denotes values
T23169 12580-12591 JJ denotes theoretical
T23168 12576-12579 DT denotes the
T23167 12566-12575 VB denotes depicting
T23166 12559-12565 NN denotes Graphs
T23165 12556-12557 -RRB- denotes )
T23164 12552-12556 CD denotes 0.05
T23163 12550-12551 SYM denotes <
T23162 12548-12549 NN denotes p
T23161 12546-12547 SYM denotes =
T23160 12544-12545 SYM denotes *
T23159 12543-12544 -LRB- denotes (
T23158 12536-12542 NN denotes TSST-1
T23157 12533-12535 TO denotes to
T23156 12524-12532 VB denotes compared
T23155 12519-12523 WRB denotes when
T23154 12512-12518 NN denotes TSST-1
T23153 12510-12511 SYM denotes +
T23152 12507-12509 NN denotes GP
T23151 12497-12506 VB denotes following
T23150 12486-12496 NN denotes production
T23149 12480-12485 NN denotes IL-1β
T23148 12477-12479 IN denotes in
T23147 12467-12476 NN denotes reduction
T23146 12460-12466 JJ denotes marked
T23145 12458-12459 DT denotes a
T23144 12454-12457 VB denotes was
T23143 12448-12453 EX denotes there
T23142 12446-12447 NN denotes h
T23141 12443-12445 CD denotes 24
T23140 12439-12442 CC denotes and
T23139 12437-12438 NN denotes h
T23138 12434-12436 CD denotes 18
T23137 12431-12433 IN denotes At
T23136 12426-12429 NN denotes LPS
T23135 12424-12425 SYM denotes +
T23134 12421-12423 NN denotes GP
T23133 12417-12420 CC denotes and
T23132 12413-12416 NN denotes LPS
T23131 12410-12412 NN denotes ng
T23130 12406-12409 CD denotes 250
T23129 12404-12405 -COMMA- denotes ,
T23128 12398-12404 NN denotes TSST-1
T23127 12396-12397 SYM denotes +
T23126 12393-12395 NN denotes GP
T23125 12391-12392 -COMMA- denotes ,
T23124 12385-12391 NN denotes TSST-1
T23123 12382-12384 NN denotes ng
T23122 12378-12381 CD denotes 250
T23121 12376-12377 -COMMA- denotes ,
T23120 12374-12376 NN denotes GP
T23119 12371-12373 NN denotes μg
T23118 12367-12370 CD denotes 100
T23117 12365-12366 -COMMA- denotes ,
T23116 12358-12365 NN denotes control
T23115 12351-12357 NN denotes medium
T23114 12346-12350 IN denotes with
T23113 12336-12345 VB denotes incubated
T23112 12331-12335 NN denotes PBMC
T23111 12325-12330 JJ denotes human
T23110 12322-12324 IN denotes by
T23109 12320-12321 -RRB- denotes )
T23108 12315-12320 NN denotes pg/ml
T23107 12314-12315 -LRB- denotes (
T23106 12303-12313 NN denotes production
T23105 12297-12302 NN denotes IL-1β
T23104 12294-12296 IN denotes of
T23103 12292-12293 -RRB- denotes )
T23102 12291-12292 NN denotes h
T23101 12288-12290 CD denotes 48
T23100 12287-12288 -LRB- denotes (
T23099 12280-12286 NN denotes course
T23098 12275-12279 NN denotes Time
T23097 12267-12273 NN denotes TSST-1
T23096 12264-12266 TO denotes to
T23095 12255-12263 VB denotes compared
T23094 12250-12254 WRB denotes when
T23093 12243-12249 NN denotes TSST-1
T23092 12241-12242 SYM denotes +
T23091 12238-12240 NN denotes GP
T23090 12228-12237 VB denotes following
T23089 12226-12227 -RRB- denotes )
T23088 12225-12226 NN denotes h
T23087 12222-12224 CD denotes 24
T23086 12220-12221 IN denotes –
T23085 12218-12219 NN denotes h
T23084 12215-12217 CD denotes 12
T23083 12214-12215 -LRB- denotes (
T23082 12199-12213 VB denotes down-regulated
T23081 12195-12198 VB denotes was
T23080 12189-12194 NN denotes IL-1β
T23079 12187-12188 -COMMA- denotes ,
T23078 12186-12187 DT denotes A
T23339 13388-13389 -RRB- denotes )
T23338 13387-13388 CD denotes 3
T23337 13385-13386 SYM denotes =
T23336 13383-13384 NN denotes n
T23335 13382-13383 -LRB- denotes (
T23334 13378-13381 NN denotes SEM
T23333 13376-13377 NN denotes ±
T23332 13371-13375 JJ denotes mean
T23331 13368-13370 IN denotes as
T23330 13362-13367 VB denotes shown
T23329 13358-13361 VB denotes are
T23328 13354-13357 CC denotes and
T23327 13348-13353 NNP denotes Elisa
T23326 13345-13347 IN denotes by
T23325 13336-13344 VB denotes obtained
T23324 13331-13335 VB denotes were
T23323 13318-13330 NN denotes supernatnant
T23322 13314-13317 DT denotes the
T23321 13311-13313 IN denotes in
T23320 13304-13310 NN denotes levels
T23319 13297-13303 NN denotes IL-1RA
T23318 13287-13295 VB denotes included
T23317 13283-13286 VB denotes are
T23316 13277-13282 NN denotes calc.
T23315 13267-13276 NN denotes GP/TSST-1
T23314 13263-13266 CC denotes and
T23313 13257-13262 NN denotes calc.
T23312 13250-13256 NN denotes GP/LPS
T23311 13246-13249 IN denotes for
T23310 13239-13245 NN denotes values
T23309 13227-13238 JJ denotes theoretical
T23308 13223-13226 DT denotes the
T23307 13213-13222 VB denotes depicting
T23306 13206-13212 NN denotes Graphs
T23305 13203-13204 -RRB- denotes )
T23304 13199-13203 CD denotes 0.05
T23303 13197-13198 SYM denotes <
T23302 13195-13196 NN denotes p
T23301 13193-13194 SYM denotes =
T23300 13191-13192 SYM denotes *
T23299 13190-13191 -LRB- denotes (
T23298 13187-13189 NN denotes GP
T23297 13183-13186 CC denotes and
T23296 13176-13182 NN denotes TSST-1
T23295 13172-13175 IN denotes for
T23294 13165-13171 NN denotes values
T23293 13158-13164 JJ denotes single
T23292 13154-13157 DT denotes the
T23291 13151-13153 IN denotes of
T23290 13142-13150 NN denotes addition
T23289 13139-13141 DT denotes an
T23288 13136-13138 TO denotes to
T23287 13127-13135 VB denotes compared
T23286 13122-13126 WRB denotes when
T23285 13111-13121 NN denotes production
T22579 10778-10779 -RRB- denotes )
T22578 10777-10778 CD denotes 3
T22577 10775-10776 SYM denotes =
T22576 10773-10774 NN denotes n
T22575 10772-10773 -LRB- denotes (
T22574 10766-10771 VB denotes shown
T22573 10763-10765 VB denotes is
T22572 10757-10762 NN denotes panel
T22571 10751-10756 JJ denotes lower
T22570 10747-10750 DT denotes the
T22569 10744-10746 IN denotes in
T22568 10742-10743 -RRB- denotes )
T22567 10740-10742 NN denotes c1
T22566 10738-10739 -COMMA- denotes ,
T22565 10736-10738 NN denotes c2
T22564 10731-10735 NN denotes NFAT
T22563 10727-10730 CC denotes and
T22562 10723-10726 NN denotes p50
T22561 10721-10722 -COMMA- denotes ,
T22560 10718-10721 NN denotes p65
T22559 10713-10717 NN denotes NFκB
T22558 10709-10712 IN denotes for
T22557 10700-10708 JJ denotes positive
T22556 10699-10700 -LRB- denotes (
T22555 10694-10698 NN denotes PBMC
T22554 10683-10693 JJ denotes GP-treated
T22553 10680-10682 IN denotes of
T22552 10671-10679 NN denotes extracts
T22551 10663-10670 JJ denotes nuclear
T22550 10660-10662 IN denotes of
T22549 10651-10659 NN denotes staining
T22548 10647-10650 CC denotes and
T22547 10641-10646 NN denotes panel
T22546 10635-10640 JJ denotes upper
T22545 10631-10634 DT denotes the
T22544 10628-10630 IN denotes in
T22543 10626-10627 -RRB- denotes )
T22542 10624-10626 NN denotes c2
T22541 10622-10623 -COMMA- denotes ,
T22540 10616-10622 NN denotes NFATc1
T22539 10612-10615 IN denotes for
T22538 10608-10611 CC denotes and
T22537 10604-10607 NN denotes p65
T22536 10602-10603 -COMMA- denotes ,
T22535 10599-10602 NN denotes p50
T22534 10594-10598 NN denotes NFκB
T22533 10590-10593 IN denotes for
T22532 10581-10589 JJ denotes positive
T22531 10575-10580 NN denotes cells
T22530 10568-10574 NN denotes Jurkat
T22529 10556-10567 JJ denotes PMA-treated
T22528 10553-10555 IN denotes of
T22527 10544-10552 NN denotes extracts
T22526 10536-10543 JJ denotes nuclear
T22525 10534-10535 -COLON- denotes ;
T22524 10529-10534 NN denotes c-rel
T22523 10527-10528 -COMMA- denotes ,
T22522 10524-10527 NN denotes p52
T22521 10519-10523 NN denotes NFκB
T22520 10510-10518 NN denotes proteins
T22519 10498-10509 JJ denotes recombinant
T22518 10497-10498 -LRB- denotes (
T22517 10488-10496 NN denotes controls
T22516 10479-10487 JJ denotes positive
T22515 10475-10478 CC denotes and
T22514 10466-10474 JJ denotes negative
T22513 10463-10465 IN denotes of
T22512 10454-10462 NN denotes staining
T22511 10446-10453 VB denotes showing
T22510 10441-10445 NN denotes blot
T22509 10437-10440 NN denotes dot
T22508 10422-10436 JJ denotes representative
T22507 10420-10421 DT denotes A
T22506 10409-10418 VB denotes performed
T22505 10405-10408 VB denotes was
T21837 10202-10203 -RRB- denotes )
T21836 10201-10202 CD denotes 4
T21835 10199-10200 SYM denotes =
T21834 10197-10198 NN denotes n
T21833 10196-10197 -LRB- denotes (
T21832 10188-10195 NN denotes control
T21831 10181-10187 NN denotes medium
T21830 10178-10180 TO denotes to
T21829 10170-10177 NN denotes respect
T21828 10165-10169 IN denotes with
T21827 10159-10164 VB denotes shown
T21826 10155-10158 VB denotes are
T21825 10153-10154 -RRB- denotes )
T21824 10149-10153 CD denotes 0.05
T21823 10147-10148 SYM denotes <
T21822 10145-10146 NN denotes p
T21821 10143-10144 SYM denotes =
T21820 10141-10142 SYM denotes *
T21819 10140-10141 -LRB- denotes (
T21818 10126-10139 NN denotes significances
T21817 10122-10125 CC denotes and
T21816 10118-10121 NN denotes SEM
T21815 10115-10117 VB denotes 1±
T21814 10112-10114 TO denotes to
T21813 10106-10111 JJ denotes equal
T21812 10102-10105 VB denotes set
T21811 10097-10101 VB denotes were
T21810 10090-10096 NN denotes levels
T21809 10082-10089 NN denotes control
T21808 10075-10081 NN denotes Medium
T21807 10072-10073 -RRB- denotes )
T21806 10067-10072 NN denotes calc.
T21805 10057-10066 NN denotes GP/TSST-1
T21804 10056-10057 -LRB- denotes (
T21803 10050-10055 NN denotes value
T21802 10038-10049 JJ denotes theoretical
T21801 10034-10037 DT denotes the
T21800 10030-10033 CC denotes and
T21799 10020-10029 NN denotes compounds
T21798 10015-10019 DT denotes both
T21797 10012-10014 IN denotes of
T21796 9997-10011 NN denotes administration
T21795 9984-9996 JJ denotes simultaneous
T21794 9981-9983 IN denotes as
T21793 9976-9980 RB denotes well
T21792 9973-9975 RB denotes as
T21791 9971-9972 -RRB- denotes )
T21790 9969-9971 NN denotes ng
T21789 9965-9968 CD denotes 250
T21788 9964-9965 -LRB- denotes (
T21787 9954-9963 NN denotes treatment
T21786 9947-9953 NN denotes TSST-1
T21785 9944-9946 CC denotes or
T21784 9942-9943 -RRB- denotes )
T21783 9940-9942 NN denotes μg
T21782 9936-9939 CD denotes 100
T21781 9932-9935 CC denotes and
T21780 9930-9931 CD denotes 1
T21779 9929-9930 -LRB- denotes (
T21778 9926-9928 NN denotes GP
T21777 9916-9925 VB denotes following
T21776 9907-9915 NN denotes activity
T21775 9899-9906 NN denotes binding
T21774 9890-9898 NN denotes NFκB-DNA
T21773 9887-9889 IN denotes of
T21772 9872-9886 NN denotes representation
T21771 9862-9871 JJ denotes Schematic
T21770 9855-9860 VB denotes shown
T21769 9852-9854 VB denotes is
T21768 9841-9851 NN denotes experiment
T21767 9826-9840 JJ denotes representative
T21766 9824-9825 DT denotes a
T21765 9819-9823 IN denotes from
T21764 9805-9818 NN denotes autoradiogram
T21763 9802-9804 NNP denotes An
T21762 9796-9801 NNP denotes 37°C.
T21761 9793-9795 IN denotes at
T21760 9791-9792 NN denotes h
T21759 9789-9790 CD denotes 1
T21758 9785-9788 IN denotes for
T21757 9781-9784 NN denotes LPS
T21756 9779-9780 SYM denotes +
T21755 9776-9778 NN denotes GP
T21754 9772-9775 CC denotes and
T21753 9765-9771 NN denotes TSST-1
T21752 9763-9764 SYM denotes +
T21751 9760-9762 NN denotes GP
T21750 9758-9759 -COMMA- denotes ,
T21749 9757-9758 -RRB- denotes )
T21748 9755-9757 NN denotes μg
T21747 9751-9754 CD denotes 100
T21746 9750-9751 -LRB- denotes (
T21745 9747-9749 NN denotes GP
T21744 9745-9746 -COMMA- denotes ,
T21743 9739-9745 NN denotes TSST-1
T21742 9737-9738 -COMMA- denotes ,
T21741 9734-9737 NN denotes LPS
T21740 9732-9733 -COMMA- denotes ,
T21739 9725-9732 NN denotes control
T21738 9718-9724 NN denotes medium
T21737 9713-9717 IN denotes with
T21736 9703-9712 VB denotes incubated
T21735 9698-9702 VB denotes were
T21734 9693-9697 NN denotes PBMC
T21733 9687-9692 JJ denotes Human
T21732 9676-9685 NN denotes TSST-1/GP
T21731 9673-9675 CC denotes or
T21730 9671-9672 -COMMA- denotes ,
T21729 9669-9671 NN denotes GP
T21728 9667-9668 -COMMA- denotes ,
T21727 9661-9667 NN denotes TSST-1
T21726 9658-9660 TO denotes to
T21725 9649-9657 VB denotes compared
T21724 9647-9648 -COMMA- denotes ,
T21723 9641-9647 NN denotes TSST-1
T21722 9639-9640 SYM denotes +
T21721 9636-9638 NN denotes GP
T21720 9626-9635 VB denotes following
T21719 9621-9625 NN denotes NFκB
T21718 9618-9620 IN denotes of
T21717 9610-9617 NN denotes binding
T21716 9606-9609 NN denotes DNA
T21715 9596-9605 VB denotes Decreased
T21714 9594-9595 -COMMA- denotes ,
T21713 9593-9594 NN denotes B
T21712 9590-9591 -RRB- denotes )
T21711 9589-9590 CD denotes 7
T21710 9587-9588 SYM denotes =
T21709 9585-9586 NN denotes n
T21708 9584-9585 -LRB- denotes (
T21707 9578-9583 VB denotes shown
T21706 9575-9577 VB denotes is
T21705 9564-9574 NN denotes experiment
T21704 9549-9563 JJ denotes representative
T21703 9547-9548 DT denotes a
T21702 9542-9546 IN denotes from
T21701 9528-9541 NN denotes autoradiogram
T21700 9525-9527 DT denotes An
T21699 9511-9523 RB denotes respectively
T21698 9509-9510 -COMMA- denotes ,
T21697 9505-9509 CD denotes -p50
T21696 9501-9504 CC denotes and
T21695 9478-9500 NN denotes NFκB-IL-8-DNA-anti-p65
T21694 9475-9477 IN denotes of
T21693 9464-9474 NN denotes supershift
T21692 9462-9463 DT denotes a
T21691 9452-9461 VB denotes indicates
T21690 9447-9451 NN denotes head
T21689 9442-9446 JJ denotes open
T21688 9438-9441 DT denotes the
T21687 9433-9437 IN denotes with
T21686 9427-9432 NN denotes Arrow
T21685 9424-9425 -RRB- denotes )
T21684 9419-9424 NN denotes shift
T21683 9416-9418 DT denotes no
T21682 9415-9416 -LRB- denotes (
T21681 9409-9414 NN denotes probe
T21680 9404-9408 JJ denotes free
T21679 9401-9403 TO denotes to
T21678 9392-9400 VB denotes compared
T21677 9384-9391 NN denotes complex
T21676 9370-9383 NN denotes NFκB-IL-8-DNA
T21675 9367-9369 CC denotes or
T21674 9356-9366 NN denotes NFIL-6-DNA
T21673 9354-9355 -COMMA- denotes ,
T21672 9346-9354 NN denotes NFκB-DNA
T21671 9344-9345 -COMMA- denotes ,
T21670 9336-9344 NN denotes NFAT-DNA
T21669 9332-9335 DT denotes the
T21668 9329-9331 IN denotes of
T21667 9320-9328 NN denotes location
T21666 9308-9319 JJ denotes migrational
T21665 9299-9307 VB denotes indicate
T22504 10400-10404 NN denotes blot
T22503 10398-10399 -RRB- denotes )
T22502 10395-10398 NN denotes dot
T22501 10394-10395 -LRB- denotes (
T22500 10388-10394 NN denotes immuno
T22499 10385-10387 DT denotes an
T22498 10383-10384 -COMMA- denotes ,
T22497 10379-10383 NN denotes NFAT
T22496 10375-10378 CC denotes and
T22495 10370-10374 NN denotes NFκB
T22494 10367-10369 TO denotes to
T22493 10359-10366 VB denotes related
T22492 10354-10358 VB denotes were
T22491 10351-10353 NN denotes GP
T22490 10348-10350 IN denotes by
T22489 10338-10347 VB denotes activated
T22488 10329-10337 NN denotes proteins
T22487 10321-10328 NN denotes binding
T22486 10317-10320 NN denotes DNA
T22485 10313-10316 DT denotes the
T22484 10305-10312 IN denotes whether
T22483 10295-10304 VB denotes determine
T22482 10292-10294 TO denotes to
T22481 10286-10291 NN denotes order
T22480 10283-10285 IN denotes In
T22479 10274-10281 NN denotes binding
T22478 10270-10273 NN denotes DNA
T22477 10259-10269 JJ denotes GP-induced
T22476 10256-10258 IN denotes in
T22475 10247-10255 VB denotes involved
T22474 10242-10246 VB denotes were
T22473 10232-10241 NN denotes NFATc2/c1
T22472 10228-10231 CC denotes and
T22471 10220-10227 NN denotes p65/p50
T22470 10215-10219 NN denotes NFκB
T21664 9294-9298 NN denotes head
T21663 9288-9293 JJ denotes black
T21662 9284-9287 DT denotes the
T21661 9279-9283 IN denotes with
T21660 9272-9278 NN denotes Arrows
T21659 9269-9270 -RRB- denotes )
T21658 9268-9269 CD denotes 1
T21657 9262-9267 JJ denotes Table
T21656 9261-9262 -LRB- denotes (
T21655 9251-9260 NN denotes promoters
T21654 9246-9250 NN denotes gene
T21653 9241-9245 NN denotes IL-8
T21652 9237-9240 CC denotes and
T21651 9232-9236 NN denotes IL-6
T21650 9230-9231 -COMMA- denotes ,
T21649 9226-9230 NN denotes TNFα
T21648 9224-9225 -COMMA- denotes ,
T21647 9220-9224 NN denotes IFNγ
T21646 9216-9219 DT denotes the
T21645 9213-9215 TO denotes to
T21644 9199-9212 VB denotes corresponding
T21643 9193-9198 NN denotes probe
T21642 9177-9192 NN denotes oligonucleotide
T21641 9167-9176 NN denotes NFκB-IL-8
T21640 9164-9166 CC denotes or
T21639 9157-9163 NN denotes NFIL-6
T21025 40091-40098 IN denotes whether
T21024 40089-40090 -COMMA- denotes ,
T21023 40081-40089 VB denotes evaluate
T21022 40078-40080 TO denotes to
T21021 40073-40077 VB denotes used
T21020 40069-40072 VB denotes was
T21019 40064-40068 NN denotes test
T21018 40045-40063 NNP denotes Kolmogorow-Smirnov
T21017 40041-40044 DT denotes The
T21016 40032-40040 NN denotes analysis
T21015 40020-40031 JJ denotes Statistical
T20575 40015-40017 NN denotes GP
T20574 40010-40014 IN denotes with
T20573 39999-40009 NN denotes incubation
T20572 39997-39998 NN denotes h
T20571 39994-39996 CD denotes 24
T20570 39988-39993 IN denotes after
T20569 39982-39987 NN denotes ELISA
T20568 39979-39981 IN denotes by
T20567 39967-39978 NN denotes supernatant
T20566 39963-39966 DT denotes the
T20565 39960-39962 IN denotes in
T20564 39951-39959 VB denotes measured
T20563 39947-39950 VB denotes was
T20562 39939-39946 NN denotes protein
T20561 39932-39938 NN denotes IL-1RA
T20560 39928-39930 NN denotes GP
T20559 39923-39927 IN denotes with
T20558 39912-39922 NN denotes incubation
T20557 39910-39911 NN denotes h
T20556 39907-39909 CD denotes 18
T20555 39897-39906 VB denotes following
T20554 39895-39896 -RRB- denotes )
T20553 39890-39895 NN denotes GAPDH
T20552 39886-39889 IN denotes for
T20551 39879-39885 NN denotes cycles
T20550 39876-39878 CD denotes 25
T20549 39874-39875 -COMMA- denotes ,
T20548 39871-39874 NN denotes sec
T20547 39868-39870 CD denotes 45
T20546 39864-39867 IN denotes for
T20545 39859-39863 NN denotes 72°C
T20544 39855-39858 CC denotes and
T20543 39851-39854 NN denotes sec
T20542 39848-39850 CD denotes 30
T20541 39844-39847 IN denotes for
T20540 39839-39843 NN denotes 50°C
T20539 39837-39838 -COMMA- denotes ,
T20538 39834-39837 NN denotes sec
T20537 39831-39833 CD denotes 30
T20536 39827-39830 IN denotes for
T20535 39822-39826 NN denotes 94°C
T20534 39818-39821 CC denotes and
T20533 39811-39817 NN denotes IL-1RA
T20532 39807-39810 IN denotes for
T20531 39800-39806 NN denotes cycles
T20530 39797-39799 CD denotes 25
T20529 39795-39796 -COMMA- denotes ,
T20528 39792-39795 NN denotes sec
T20527 39789-39791 CD denotes 30
T20526 39787-39788 -COMMA- denotes ,
T20525 39783-39787 NN denotes 72°C
T20524 39781-39782 -COMMA- denotes ,
T20523 39778-39781 NN denotes sec
T20522 39775-39777 CD denotes 30
T20521 39773-39774 -COMMA- denotes ,
T20520 39769-39773 NN denotes 55°C
T20519 39767-39768 -COMMA- denotes ,
T20518 39764-39767 NN denotes sec
T20517 39761-39763 CD denotes 30
T20516 39759-39760 -COMMA- denotes ,
T20515 39755-39759 NN denotes 95°C
T20514 39754-39755 -LRB- denotes (
T20513 39752-39753 -RRB- denotes )
T20512 39746-39752 NN denotes Biomol
T20511 39745-39746 -LRB- denotes (
T20510 39735-39744 NN denotes mastermix
T20509 39731-39734 NN denotes PCR
T20508 39729-39730 -DQE- denotes "
T20507 39724-39729 JJ denotes sweet
T20506 39723-39724 -DQS- denotes "
T20505 39714-39722 NNP denotes HotStart
T20504 39712-39713 DT denotes a
T20503 39707-39711 IN denotes with
T20502 39703-39706 NN denotes PCR
T20501 39700-39702 IN denotes by
T20500 39688-39699 NN denotes transcripts
T20499 39682-39687 NN denotes GAPDH
T20498 39678-39681 CC denotes and
T20497 39671-39677 NN denotes IL-1RA
T20496 39667-39670 IN denotes for
T20495 39658-39666 VB denotes analysed
T20494 39654-39657 CC denotes and
T20493 39652-39653 -RRB- denotes )
T20492 39646-39652 NN denotes Biomol
T20491 39645-39646 -LRB- denotes (
T20490 39641-39644 NN denotes kit
T20489 39634-39640 NNP denotes Strand
T20488 39628-39633 NNP denotes First
T20487 39622-39627 NNP denotes Ready
T20486 39614-39621 NN denotes Reactin
T20485 39609-39613 IN denotes with
T20484 39604-39608 NN denotes cDNA
T20483 39599-39603 IN denotes into
T20482 39587-39598 VB denotes transcribed
T20481 39583-39586 VB denotes was
T20480 39579-39582 NN denotes RNA
T20479 39569-39578 NN denotes messenger
T20478 39565-39568 CC denotes and
T20477 39563-39564 -RRB- denotes )
T20476 39556-39563 NNP denotes Germany
T20475 39554-39555 -COMMA- denotes ,
T20474 39548-39554 NN denotes Qiagen
T20473 39547-39548 -LRB- denotes (
T20472 39543-39546 NN denotes kit
T20471 39536-39542 NN denotes RNeasy
T20470 39533-39535 DT denotes an
T20469 39528-39532 IN denotes with
T20468 39519-39527 VB denotes isolated
T20467 39515-39518 VB denotes was
T20466 39511-39514 NN denotes RNA
T20465 39506-39510 NN denotes PBMC
T20464 39496-39504 NN denotes promoter
T20463 39489-39495 NN denotes IL-1RA
T20462 39485-39488 DT denotes the
T20461 39478-39484 IN denotes within
T20460 39472-39477 NN denotes sites
T20459 39464-39471 NN denotes binding
T20458 39462-39463 -RRB- denotes )
T20457 39459-39462 NN denotes TCT
T20456 39455-39458 NN denotes CTA
T20455 39451-39454 NN denotes TTA
T20454 39447-39450 NN denotes TAT
T20453 39443-39446 NN denotes AAA
T21638 9155-9156 -COMMA- denotes ,
T21637 9151-9155 NN denotes NFκB
T21636 9149-9150 -COMMA- denotes ,
T21635 9145-9149 NN denotes NFAT
T21634 9133-9144 JJ denotes 32P-labeled
T21633 9131-9132 DT denotes a
T21632 9126-9130 IN denotes with
T21631 9116-9125 VB denotes incubated
T21630 9111-9115 VB denotes were
T21629 9102-9110 NN denotes extracts
T21628 9094-9101 NNP denotes Nuclear
T21627 9088-9093 NNP denotes 37°C.
T21626 9085-9087 IN denotes at
T21625 9083-9084 NN denotes h
T21624 9081-9082 CD denotes 1
T21623 9077-9080 IN denotes for
T21622 9075-9076 -RRB- denotes )
T21621 9073-9075 NN denotes μg
T21620 9069-9072 CD denotes 100
T21619 9065-9068 CC denotes and
T21618 9063-9064 CD denotes 1
T21617 9062-9063 -LRB- denotes (
T21616 9059-9061 NN denotes GP
T21615 9056-9058 CC denotes or
T21614 9048-9055 NN denotes control
T21613 9041-9047 NN denotes medium
T21612 9036-9040 IN denotes with
T21611 9026-9035 VB denotes incubated
T21610 9021-9025 VB denotes were
T21609 9016-9020 NN denotes PBMC
T21608 9010-9015 JJ denotes Human
T21607 9002-9008 NN denotes NFIL-6
T21606 8998-9001 CC denotes and
T21605 8993-8997 NN denotes NFκB
T21604 8991-8992 -COMMA- denotes ,
T21603 8987-8991 NN denotes NFAT
T21602 8984-8986 IN denotes of
T21601 8976-8983 NN denotes binding
T21600 8972-8975 NN denotes DNA
T21599 8969-8971 TO denotes to
T21598 8965-8968 VB denotes led
T21597 8962-8964 NN denotes GP
T21596 8960-8961 -COMMA- denotes ,
T21595 8959-8960 DT denotes A
T21167 40915-40916 -RRB- denotes )
T21166 40908-40915 NNP denotes Germany
T21165 40906-40907 -COMMA- denotes ,
T21164 40899-40906 NNP denotes Erkrath
T21163 40897-40898 -COMMA- denotes ,
T21162 40889-40897 NNP denotes Software
T21161 40881-40888 NNP denotes Science
T21160 40876-40880 NNP denotes SPSS
T21159 40874-40875 -COLON- denotes ;
T21158 40867-40874 NNP denotes Windows
T21157 40863-40866 IN denotes for
T21156 40858-40862 NN denotes SPSS
T21155 40857-40858 -LRB- denotes (
T21154 40855-40856 -COMMA- denotes ,
T21153 40854-40855 -RRB- denotes )
T21152 40842-40854 NN denotes distribution
T21151 40831-40841 JJ denotes non-normal
T21150 40830-40831 -LRB- denotes (
T21149 40825-40829 NN denotes test
T21148 40813-40824 NNP denotes Signed-Rank
T21147 40804-40812 NNP denotes Wilcoxon
T21146 40800-40803 DT denotes the
T21145 40797-40799 CC denotes or
T21144 40795-40796 -RRB- denotes )
T21143 40783-40795 NN denotes distribution
T21142 40776-40782 JJ denotes normal
T21141 40775-40776 -LRB- denotes (
T21140 40768-40774 NN denotes t-test
T21139 40765-40767 POS denotes 's
T21138 40758-40765 NNP denotes Student
T21137 40754-40757 DT denotes the
T21136 40748-40753 VB denotes using
T21135 40739-40747 VB denotes analysed
T21134 40734-40738 VB denotes were
T21133 40732-40733 -RRB- denotes )
T21132 40727-40732 NN denotes calc.
T21131 40717-40726 NN denotes GP/TSST-1
T21130 40714-40716 IN denotes vs
T21129 40707-40713 NN denotes TSST-1
T21128 40705-40706 SYM denotes +
T21127 40702-40704 NN denotes GP
T21126 40694-40701 NN denotes example
T21125 40690-40693 IN denotes for
T21124 40689-40690 -LRB- denotes (
T21123 40682-40688 NN denotes values
T21122 40670-40681 JJ denotes theoretical
T21121 40666-40669 CC denotes and
T21120 40661-40665 NN denotes data
T21119 40648-40660 JJ denotes experimental
T21118 40640-40647 IN denotes between
T21117 40637-40639 IN denotes as
T21116 40632-40636 RB denotes well
T21115 40629-40631 RB denotes as
T21114 40627-40628 -RRB- denotes )
T21113 40624-40627 NN denotes LPS
T21112 40621-40623 IN denotes vs
T21111 40618-40620 NN denotes GP
T21110 40610-40617 NN denotes example
T21109 40606-40609 IN denotes for
T21108 40605-40606 -LRB- denotes (
T21107 40600-40604 NN denotes data
T21106 40587-40599 JJ denotes experimental
T21105 40579-40586 IN denotes between
T21104 40567-40578 NN denotes differences
T21103 40564-40566 IN denotes of
T21102 40550-40563 NN denotes Significances
T21101 40547-40548 CD denotes 6
T21100 40543-40546 CC denotes and
T21099 40541-40542 -COMMA- denotes ,
T21098 40540-40541 CD denotes 5
T21097 40538-40539 -COMMA- denotes ,
T21096 40537-40538 CD denotes 4
T21095 40535-40536 -COMMA- denotes ,
T21094 40534-40535 CD denotes 3
T21093 40532-40533 -COMMA- denotes ,
T21092 40530-40532 NN denotes 1B
T21091 40525-40529 NNP denotes Fig.
T21090 40520-40524 IN denotes into
T21089 40513-40519 NN denotes values
T21088 40507-40512 DT denotes these
T21087 40501-40506 VB denotes added
T21086 40497-40500 CC denotes and
T21085 40489-40496 NN denotes effects
T21084 40478-40488 JJ denotes individual
T21083 40474-40477 DT denotes the
T21082 40471-40473 IN denotes of
T21081 40467-40470 NN denotes sum
T21080 40463-40466 DT denotes the
T21079 40452-40462 VB denotes calculated
T21078 40449-40451 PRP denotes we
T21077 40447-40448 -RRB- denotes )
T21076 40442-40447 NN denotes calc.
T21075 40432-40441 NN denotes GP/TSST-1
T21074 40429-40431 IN denotes vs
T21073 40422-40428 NN denotes TSST-1
T21072 40420-40421 SYM denotes +
T21071 40417-40419 NN denotes GP
T21070 40409-40416 NN denotes example
T21069 40405-40408 IN denotes for
T21068 40404-40405 -LRB- denotes (
T21067 40398-40403 NN denotes value
T21066 40386-40397 JJ denotes theoretical
T21065 40384-40385 DT denotes a
T21064 40381-40383 TO denotes to
T21063 40376-40380 NN denotes data
T21062 40363-40375 JJ denotes experimental
T21061 40355-40362 VB denotes compare
T21060 40352-40354 TO denotes To
T21059 40349-40350 -RRB- denotes )
T21058 40337-40349 NN denotes distribution
T21057 40326-40336 JJ denotes non-normal
T21056 40325-40326 -LRB- denotes (
T21055 40320-40324 NN denotes test
T21054 40311-40319 NNP denotes Spearman
T21053 40307-40310 DT denotes the
T21052 40304-40306 CC denotes or
T21051 40302-40303 -RRB- denotes )
T21050 40290-40302 NN denotes distribution
T21049 40283-40289 JJ denotes normal
T21048 40282-40283 -LRB- denotes (
T21047 40277-40281 NN denotes test
T21046 40269-40276 NNP denotes Pearson
T21045 40265-40268 DT denotes the
T21044 40262-40264 IN denotes by
T21043 40253-40261 VB denotes analyzed
T21042 40248-40252 VB denotes were
T21041 40234-40247 NN denotes significances
T21040 40220-40233 JJ denotes corresponding
T21039 40216-40219 CC denotes and
T21038 40203-40215 NN denotes coefficients
T21037 40191-40202 NN denotes Correlation
T21036 40178-40189 VB denotes distributed
T21035 40169-40177 RB denotes normally
T21034 40164-40168 VB denotes were
T21033 40156-40163 NN denotes factors
T21032 40142-40155 NN denotes transcription
T21031 40139-40141 TO denotes to
T21030 40128-40138 NN denotes activities
T21029 40120-40127 NN denotes binding
T21028 40116-40119 CC denotes and
T21027 40108-40115 NN denotes amounts
T21026 40099-40107 NN denotes cytokine
T20452 39439-39442 NN denotes GTA
T20451 39435-39438 NN denotes AAG
T20450 39431-39434 NN denotes GAA
T20449 39427-39430 NN denotes GCA
T20448 39423-39426 NN denotes GGC
T20447 39422-39423 -LRB- denotes (
T20446 39413-39421 NN denotes NFATP2/3
T20445 39409-39412 CC denotes and
T20444 39407-39408 -RRB- denotes )
T20443 39404-39407 NN denotes GGG
T20442 39400-39403 NNP denotes AGT
T20441 39396-39399 NNP denotes CTT
T20440 39392-39395 NNP denotes ACA
T20439 39388-39391 NNP denotes GCG
T20438 39384-39387 NNP denotes ATT
T20437 39380-39383 NNP denotes TGG
T20436 39376-39379 NNP denotes CAG
T20435 39372-39375 NN denotes CAA
T20434 39368-39371 NN denotes TTA
T20433 39367-39368 -LRB- denotes (
T20432 39360-39366 NN denotes NFIL-6
T20431 39356-39359 IN denotes for
T20430 39349-39355 NN denotes oligos
T20429 39341-39348 VB denotes mutated
T20428 39331-39340 VB denotes including
T20427 39329-39330 -COMMA- denotes ,
T20370 39000-39001 -COLON- denotes :
T20369 38999-39000 -RRB- denotes )
T20368 38989-38999 NN denotes inhibition
T20367 38987-38988 NN denotes %
T20366 38985-38987 CD denotes 50
T20365 38980-38984 IN denotes upon
T20364 38974-38979 VB denotes based
T20363 38969-38973 VB denotes were
T20362 38954-38968 NN denotes concentrations
T20361 38953-38954 -LRB- denotes (
T20360 38942-38952 NN denotes substances
T20359 38932-38941 VB denotes following
T20358 38928-38931 DT denotes the
T20357 38925-38927 IN denotes of
T20356 38920-38924 DT denotes each
T20355 38915-38919 IN denotes with
T20354 38913-38914 NN denotes h
T20353 38911-38912 CD denotes 1
T20352 38907-38910 IN denotes for
T20351 38897-38906 VB denotes incubated
T20350 38892-38896 VB denotes were
T20349 38887-38891 NN denotes PBMC
T20348 38885-38886 -COMMA- denotes ,
T20347 38877-38885 NN denotes promoter
T20346 38870-38876 NN denotes IL-1RA
T20345 38866-38869 DT denotes the
T20344 38863-38865 TO denotes to
T20343 38855-38862 NN denotes factors
T20342 38841-38854 NN denotes transcription
T20341 38838-38840 IN denotes of
T20340 38830-38837 NN denotes binding
T20339 38826-38829 CC denotes and
T20338 38812-38825 NN denotes translocation
T20337 38804-38811 VB denotes inhibit
T20336 38801-38803 TO denotes To
T20335 38793-38800 NN denotes factors
T20334 38779-38792 NN denotes transcription
T20333 38776-38778 IN denotes of
T20332 38765-38775 NN denotes Inhibition
T19971 38752-38762 NN denotes statistics
T19970 38748-38751 DT denotes the
T19969 38745-38747 IN denotes in
T19968 38736-38744 VB denotes included
T19967 38732-38735 VB denotes was
T19966 38724-38731 NN denotes release
T19965 38715-38723 NN denotes cytokine
T19964 38703-38714 JJ denotes spontaneous
T19963 38700-38702 DT denotes no
T19962 38692-38699 VB denotes showing
T19961 38685-38691 NN denotes donors
T19960 38682-38684 IN denotes in
T19959 38673-38681 VB denotes observed
T19958 38668-38672 NN denotes PBMC
T19957 38665-38667 IN denotes of
T19956 38653-38664 NN denotes stimulation
T19955 38648-38652 RB denotes Only
T19954 38641-38646 NN denotes curve
T19953 38632-38640 JJ denotes standard
T19952 38628-38631 DT denotes the
T19951 38625-38627 IN denotes of
T19950 38619-38624 NN denotes range
T19949 38615-38618 DT denotes the
T19948 38608-38614 IN denotes within
T19947 38604-38607 DT denotes all
T19946 38599-38603 VB denotes were
T19945 38591-38598 NN denotes amounts
T19944 38582-38590 NN denotes Cytokine
T19943 38579-38580 -RRB- denotes )
T19942 38573-38579 NNP denotes BioRad
T19941 38571-38572 -COMMA- denotes ,
T19940 38565-38571 NNP denotes Reader
T19939 38554-38564 NNP denotes Microplate
T19938 38551-38553 CC denotes or
T19937 38543-38550 NNP denotes Austria
T19936 38541-38542 -COMMA- denotes ,
T19935 38533-38541 NNP denotes Salzburg
T19934 38531-38532 -COMMA- denotes ,
T19933 38524-38531 NNP denotes Labotec
T19932 38517-38523 NNP denotes Anthos
T19931 38516-38517 -LRB- denotes (
T19930 38509-38515 NN denotes reader
T19929 38503-38508 NN denotes plate
T19928 38497-38502 NN denotes ELISA
T19927 38494-38496 DT denotes an
T19926 38488-38493 VB denotes using
T19925 38477-38487 VB denotes quantified
T19924 38472-38476 VB denotes were
T19923 38462-38471 NN denotes cytokines
T19922 38458-38461 DT denotes All
T20426 39323-39329 IN denotes before
T20425 39313-39322 VB denotes described
T20424 39310-39312 IN denotes as
T20423 39307-39309 NN denotes GP
T20422 39302-39306 IN denotes with
T20421 39291-39301 NN denotes incubation
T20420 39289-39290 NN denotes h
T20419 39287-39288 CD denotes 1
T20418 39281-39286 IN denotes after
T20417 39270-39280 VB denotes determined
T20416 39265-39269 VB denotes were
T20415 39258-39264 NN denotes shifts
T20414 39253-39257 NN denotes Band
T20413 39249-39251 NN denotes GP
T20412 39244-39248 IN denotes with
T20411 39233-39243 NN denotes incubation
T20410 39230-39232 TO denotes to
T20409 39224-39229 JJ denotes prior
T20408 39222-39223 -RRB- denotes )
T20407 39209-39222 NNP denotes Biotechnology
T20406 39204-39208 NNP denotes Cruz
T20405 39198-39203 NNP denotes Santa
T20404 39197-39198 -LRB- denotes (
T20403 39183-39196 NN denotes cycloheximide
T20402 39177-39182 NN denotes μg/ml
T20401 39174-39176 CD denotes 10
T20400 39172-39173 -COLON- denotes ;
T20399 39171-39172 -RRB- denotes )
T20398 39164-39171 NNP denotes Germany
T20397 39162-39163 -COMMA- denotes ,
T20396 39157-39162 NNP denotes Soden
T20395 39153-39156 NNP denotes Bad
T20394 39151-39152 -COMMA- denotes ,
T20393 39140-39151 NNP denotes Biosciences
T20392 39123-39139 NNP denotes Calbiochem-Merck
T20391 39122-39123 -LRB- denotes (
T20390 39120-39121 NN denotes A
T20389 39108-39119 NN denotes cyclosporin
T20388 39102-39107 NN denotes ng/ml
T20387 39098-39101 CD denotes 400
T20386 39096-39097 -COLON- denotes ;
T20385 39095-39096 -RRB- denotes )
T20384 39088-39095 NNP denotes Germany
T20383 39086-39087 -COMMA- denotes ,
T20382 39079-39086 NNP denotes Hamburg
T20381 39077-39078 -COMMA- denotes ,
T20380 39071-39077 NNP denotes Biomol
T20379 39070-39071 -LRB- denotes (
T20378 39068-39069 -COMMA- denotes ,
T20377 39067-39068 -RRB- denotes )
T20376 39020-39067 NN denotes caffeic-3,4-dihydroxycinnamic-acid-phenyl-ester
T20375 39019-39020 -LRB- denotes (
T20374 39014-39018 NN denotes CAPE
T20373 39011-39013 IN denotes of
T20372 39005-39010 NN denotes μg/ml
T20371 39002-39004 CD denotes 50
T19921 38447-38456 NN denotes standards
T19920 38443-38446 DT denotes the
T19919 38439-38442 IN denotes for
T19918 38434-38438 VB denotes used
T19917 38429-38433 DT denotes that
T19916 38426-38428 IN denotes as
T19915 38419-38425 NN denotes buffer
T19914 38414-38418 JJ denotes same
T19913 38410-38413 DT denotes the
T19912 38407-38409 IN denotes in
T19911 38399-38406 VB denotes diluted
T19910 38394-38398 VB denotes were
T19909 38386-38393 NN denotes Samples
T19908 38383-38384 -RRB- denotes ]
T19907 38381-38383 CD denotes 46
T19906 38380-38381 -LRB- denotes [
T19905 38370-38379 VB denotes described
T19904 38359-38369 RB denotes previously
T19903 38356-38358 IN denotes as
T19902 38351-38355 VB denotes done
T19901 38347-38350 VB denotes was
T19900 38342-38346 NN denotes IL-1
T19899 38339-38341 IN denotes of
T19898 38327-38338 NN denotes bioactivity
T19897 38323-38326 DT denotes the
T19896 38319-38322 IN denotes for
T19824 37964-37967 CC denotes and
T19823 37961-37963 CD denotes 36
T19822 37959-37960 -COMMA- denotes ,
T19821 37957-37959 CD denotes 30
T19820 37955-37956 -COMMA- denotes ,
T19819 37953-37955 CD denotes 24
T19818 37951-37952 -COMMA- denotes ,
T19817 37949-37951 CD denotes 18
T19816 37947-37948 -COMMA- denotes ,
T19815 37945-37947 CD denotes 12
T19814 37943-37944 -COMMA- denotes ,
T19813 37942-37943 CD denotes 9
T19812 37940-37941 -COMMA- denotes ,
T19811 37939-37940 CD denotes 6
T19810 37937-37938 -COMMA- denotes ,
T19809 37936-37937 CD denotes 3
T19808 37926-37935 VB denotes harvested
T19807 37921-37925 VB denotes were
T19806 37912-37920 NN denotes cultures
T19805 37907-37911 NN denotes cell
T19804 37904-37906 IN denotes of
T19803 37891-37903 NN denotes Supernatants
T19802 37878-37890 NN denotes measurements
T19801 37869-37877 NN denotes Cytokine
T19895 38309-38318 NN denotes indicator
T19894 38306-38308 DT denotes an
T19893 38303-38305 IN denotes as
T19892 38298-38302 NN denotes IL-2
T19891 38295-38297 IN denotes of
T19890 38280-38294 NN denotes Quantification
T19889 38277-38278 -RRB- denotes ]
T19888 38275-38277 CD denotes 57
T19887 38274-38275 -LRB- denotes [
T19886 38264-38273 VB denotes described
T19885 38253-38263 RB denotes previously
T19884 38250-38252 IN denotes as
T19883 38244-38249 NN denotes ELISA
T19882 38241-38243 DT denotes an
T19881 38235-38240 VB denotes using
T19880 38233-38234 CD denotes 1
T19879 38228-38232 NN denotes TGFβ
T19878 38224-38227 CC denotes and
T19877 38222-38223 -COMMA- denotes ,
T19876 38221-38222 -RRB- denotes )
T19875 38214-38221 NNP denotes Germany
T19874 38212-38213 -COMMA- denotes ,
T19873 38191-38212 NNP denotes Wiesbaden-Nordenstadt
T19872 38190-38191 -LRB- denotes (
T19871 38182-38189 NNP denotes Systems
T19870 38180-38181 NNP denotes D
T19869 38179-38180 CC denotes &
T19868 38178-38179 NNP denotes R
T19867 38173-38177 IN denotes from
T19866 38167-38172 NN denotes ELISA
T19865 38164-38166 DT denotes an
T19864 38161-38163 IN denotes by
T19863 38156-38160 NN denotes IL-8
T19862 38152-38155 CC denotes and
T19861 38145-38151 NN denotes IL-1RA
T19860 38143-38144 -COMMA- denotes ,
T19859 38142-38143 -RRB- denotes )
T19858 38135-38142 NNP denotes Austria
T19857 38133-38134 -COMMA- denotes ,
T19856 38127-38133 NNP denotes Vienna
T19855 38126-38127 -LRB- denotes (
T19854 38118-38125 NNP denotes Systems
T19853 38111-38117 NNP denotes Bender
T19852 38106-38110 IN denotes from
T19851 38100-38105 NN denotes ELISA
T19850 38097-38099 DT denotes an
T19849 38091-38096 VB denotes using
T19848 38080-38090 VB denotes determined
T19847 38075-38079 VB denotes were
T19846 38070-38074 NN denotes IL-6
T19845 38066-38069 CC denotes and
T19844 38061-38065 NN denotes IL-1
T19843 38059-38060 -COMMA- denotes ,
T19842 38055-38059 NN denotes TNFα
T19841 38053-38054 -COMMA- denotes ,
T19840 38049-38053 NN denotes IFNγ
T19839 38043-38047 RB denotes once
T19838 38038-38042 RB denotes only
T19837 38031-38037 VB denotes thawed
T19836 38027-38030 CC denotes and
T19835 38022-38026 VB denotes used
T19834 38016-38021 IN denotes until
T19833 38013-38015 NN denotes °C
T19832 38009-38012 CD denotes -80
T19831 38006-38008 IN denotes at
T19830 37999-38005 VB denotes stored
T19829 37995-37998 CC denotes and
T19828 37983-37994 NN denotes stimulation
T19827 37977-37982 IN denotes after
T19826 37971-37976 NN denotes hours
T19825 37968-37970 CD denotes 48
T19361 37865-37866 -RRB- denotes )
T19360 37862-37865 NNP denotes USA
T19359 37860-37861 -COMMA- denotes ,
T19358 37858-37860 NNP denotes CA
T19357 37856-37857 -COMMA- denotes ,
T19356 37846-37856 NNP denotes Burlingame
T19355 37841-37845 NNP denotes Inc.
T19354 37828-37840 NNP denotes Laboratories
T18963 36587-36594 NN denotes binding
T18962 36578-36586 JJ denotes specific
T18961 36573-36577 IN denotes with
T18960 36565-36572 VB denotes compete
T18959 36561-36564 RB denotes not
T18958 36557-36560 VB denotes did
T18957 36551-36556 WDT denotes which
T18956 36549-36550 -COMMA- denotes ,
T18955 36545-36549 VB denotes used
T18954 36541-36544 VB denotes was
T18953 36539-36540 -RRB- denotes )
T18952 36538-36539 CD denotes 1
T18951 36532-36537 JJ denotes Table
T18950 36530-36531 -COMMA- denotes ,
T18949 36527-36530 NN denotes DNA
T18948 36517-36526 JJ denotes unrelated
T18947 36516-36517 -LRB- denotes (
T18946 36512-36515 NN denotes DNA
T18945 36506-36511 NN denotes Oct-1
T18944 36503-36505 IN denotes of
T18943 36496-36502 NN denotes excess
T18942 36490-36495 JJ denotes molar
T18941 36482-36489 JJ denotes 30-fold
T18940 36480-36481 DT denotes a
T18939 36478-36479 -COMMA- denotes ,
T18938 36469-36478 NN denotes reactions
T18937 36456-36468 JJ denotes non-specific
T18936 36448-36455 VB denotes exclude
T18935 36445-36447 TO denotes To
T18934 36442-36443 -RRB- denotes )
T18933 36437-36442 VB denotes shown
T18932 36433-36436 RB denotes not
T18931 36428-36432 NN denotes data
T18930 36427-36428 -LRB- denotes (
T18929 36417-36426 VB denotes performed
T18928 36412-36416 VB denotes were
T18927 36403-36411 NN denotes antibody
T18926 36396-36402 NN denotes p65/50
T18925 36387-36395 JJ denotes combined
T18924 36385-36386 DT denotes a
T18923 36380-36384 IN denotes with
T18922 36375-36379 NN denotes NFκB
T18921 36371-36374 IN denotes for
T18920 36364-36370 NN denotes assays
T18919 36353-36363 NN denotes supershift
T18918 36351-36352 -COMMA- denotes ,
T18917 36344-36351 NN denotes binding
T18916 36341-36343 IN denotes of
T18915 36329-36340 NN denotes specificity
T18914 36325-36328 IN denotes For
T18913 36315-36323 NN denotes extracts
T18912 36307-36314 JJ denotes nuclear
T18911 36303-36306 DT denotes the
T18910 36300-36302 TO denotes to
T18909 36294-36299 VB denotes added
T18908 36290-36293 VB denotes was
T18907 36283-36289 NN denotes oligos
T18906 36273-36282 JJ denotes unlabeled
T18905 36270-36272 IN denotes of
T18904 36268-36269 -RRB- denotes )
T18903 36263-36268 NN denotes 5–50×
T18902 36262-36263 -LRB- denotes (
T18901 36255-36261 JJ denotes excess
T18900 36252-36254 DT denotes an
T18899 36250-36251 -COMMA- denotes ,
T18898 36239-36250 NN denotes experiments
T18897 36234-36238 JJ denotes such
T18896 36230-36233 IN denotes For
T18895 36220-36228 NN denotes proteins
T18894 36212-36219 JJ denotes nuclear
T18893 36209-36211 TO denotes to
T18892 36201-36208 NN denotes binding
T18891 36188-36200 JJ denotes non-specific
T18890 36180-36187 VB denotes prevent
T18889 36177-36179 TO denotes to
T18888 36171-36176 NN denotes order
T18887 36168-36170 IN denotes in
T18886 36164-36167 RP denotes out
T18885 36156-36163 VB denotes carried
T18884 36151-36155 VB denotes were
T18883 36149-36150 -RRB- denotes )
T18882 36144-36149 IN denotes above
T18881 36140-36143 VB denotes see
T18880 36139-36140 -LRB- denotes (
T18879 36133-36138 NN denotes sites
T18878 36125-36132 NN denotes binding
T19353 37821-37827 NNP denotes Vector
T19352 37820-37821 -LRB- denotes (
T19351 37816-37819 NN denotes kit
T19350 37807-37815 NN denotes staining
T19349 37795-37806 NNP denotes Vectastain®
T19348 37791-37794 DT denotes the
T19347 37785-37790 VB denotes using
T19346 37775-37784 VB denotes developed
T19345 37771-37774 VB denotes was
T19344 37766-37770 NN denotes blot
T19343 37762-37765 DT denotes The
T19342 37759-37760 -RRB- denotes )
T19341 37756-37759 NN denotes BSA
T19340 37754-37755 NN denotes %
T19339 37749-37754 NN denotes PBS/1
T19338 37746-37748 IN denotes in
T19337 37742-37745 CD denotes 500
T19336 37741-37742 -COLON- denotes :
T19335 37740-37741 CD denotes 1
T19334 37739-37740 -LRB- denotes (
T19333 37730-37738 NN denotes antibody
T19332 37720-37729 JJ denotes secondary
T19331 37697-37719 JJ denotes phosphatase-conjugated
T19330 37688-37696 NN denotes alkaline
T19329 37684-37687 DT denotes the
T19328 37679-37683 IN denotes with
T19327 37669-37678 VB denotes incubated
T19326 37665-37668 CC denotes and
T19325 37659-37664 RB denotes again
T19324 37652-37658 VB denotes washed
T19323 37650-37651 -COMMA- denotes ,
T19322 37647-37650 NN denotes BSA
T19321 37645-37646 NN denotes %
T19320 37640-37645 NN denotes PBS/1
T19319 37637-37639 IN denotes in
T18877 36116-36124 NN denotes promoter
T18876 36107-36115 NN denotes cytokine
T18875 36103-36106 DT denotes the
T18874 36100-36102 IN denotes of
T18873 36093-36099 NN denotes oligos
T18872 36085-36092 VB denotes mutated
T18871 36075-36084 JJ denotes unlabeled
T18870 36071-36074 CC denotes and
T18869 36063-36070 VB denotes labeled
T18868 36058-36062 IN denotes with
T18867 36046-36057 NN denotes experiments
T18866 36034-36045 NN denotes Competition
T18865 36024-36032 NN denotes controls
T18864 36011-36023 JJ denotes unstimulated
T18863 36008-36010 IN denotes of
T18862 36002-36007 NN denotes bands
T18861 35999-36001 TO denotes to
T18860 35988-35998 VB denotes normalized
T18859 35984-35987 VB denotes was
T18858 35978-35983 NN denotes bands
T18857 35970-35977 VB denotes shifted
T18856 35967-35969 IN denotes of
T18855 35957-35966 NN denotes intensity
T18854 35953-35956 DT denotes The
T18853 35950-35951 -RRB- denotes ]
T18852 35948-35950 CD denotes 56
T18814 35721-35732 NN denotes Preparation
T18476 35703-35705 POS denotes 's
T18475 35691-35703 NN denotes manufacturer
T18474 35687-35690 DT denotes the
T18473 35684-35686 TO denotes to
T18472 35674-35683 VB denotes according
T18471 35672-35673 -RRB- denotes )
T18470 35663-35672 NNP denotes Pharmacia
T18469 35662-35663 -LRB- denotes (
T18468 35654-35661 NNP denotes Columns
T18467 35648-35653 NNP denotes Micro
T18466 35643-35647 NNP denotes G-50
T18465 35637-35642 NNP denotes Quant
T18464 35631-35636 NNP denotes Probe
T18463 35625-35630 VB denotes using
T18462 35614-35624 NN denotes filtration
T18461 35610-35613 NN denotes gel
T18460 35606-35609 IN denotes via
T18459 35597-35605 VB denotes purified
T18458 35592-35596 VB denotes were
T18457 35585-35591 NN denotes oligos
T18456 35582-35584 NN denotes ds
T18455 35578-35581 DT denotes the
T18454 35576-35577 -COMMA- denotes ,
T18453 35566-35576 RB denotes Afterwards
T18452 35552-35564 RB denotes respectively
T18451 35550-35551 -COMMA- denotes ,
T18450 35542-35550 NN denotes proteins
T18449 35537-35541 NN denotes NFκB
T18448 35533-35536 CC denotes and
T18447 35528-35532 NN denotes NFAT
T18446 35525-35527 IN denotes of
T18445 35517-35524 NN denotes binding
T18444 35513-35516 DT denotes the
T18443 35509-35512 IN denotes for
T18442 35501-35508 JJ denotes crucial
T18441 35498-35500 VB denotes be
T18440 35495-35497 TO denotes to
T18439 35490-35494 VB denotes seem
T18438 35484-35489 WDT denotes which
T18437 35482-35483 -COMMA- denotes ,
T18436 35473-35482 NN denotes sequences
T18435 35468-35472 IN denotes with
T18434 35458-35467 VB denotes interfere
T18433 35455-35457 TO denotes to
T18432 35446-35454 VB denotes reported
T18431 35441-35445 VB denotes been
T18430 35436-35440 VB denotes have
T18429 35434-35435 -RRB- denotes ]
T18428 35432-35434 CD denotes 55
T18427 35431-35432 -LRB- denotes [
T18426 35422-35430 NN denotes promoter
T18425 35417-35421 NN denotes TNFα
T18424 35413-35416 DT denotes the
T18423 35410-35412 IN denotes of
T18422 35401-35409 NN denotes sequence
T18421 35391-35400 NN denotes consensus
T18420 35389-35390 NN denotes κ
T18419 35385-35388 DT denotes the
T18418 35382-35384 IN denotes in
T18417 35378-35381 CC denotes and
T18416 35376-35377 -RRB- denotes ]
T18415 35374-35376 CD denotes 29
T18414 35373-35374 -LRB- denotes [
T18413 35364-35372 NN denotes promoter
T18412 35359-35363 NN denotes IFNγ
T18411 35355-35358 DT denotes the
T18410 35352-35354 IN denotes of
T18409 35347-35351 NN denotes site
T18408 35344-35346 NN denotes P2
T18407 35340-35343 DT denotes the
T18406 35337-35339 IN denotes in
T18851 35947-35948 -LRB- denotes [
T18850 35941-35946 NN denotes setup
T18849 35928-35940 JJ denotes experimental
T18848 35924-35927 PRP-DOLLAR- denotes our
T18847 35920-35923 IN denotes for
T18846 35911-35919 VB denotes modified
T18845 35907-35910 CC denotes and
T18844 35905-35906 -RRB- denotes ]
T18843 35903-35905 CD denotes 27
T18842 35902-35903 -LRB- denotes [
T18841 35898-35901 FW denotes al.
T18840 35895-35897 FW denotes et
T18839 35889-35894 NNP denotes Trede
T18838 35886-35888 IN denotes by
T18837 35876-35885 VB denotes described
T18836 35866-35875 NN denotes technique
T18835 35864-35865 DT denotes a
T18834 35861-35863 TO denotes to
T18833 35851-35860 VB denotes according
T18832 35842-35850 VB denotes prepared
T18831 35837-35841 VB denotes were
T18830 35831-35836 NN denotes PBMCs
T18829 35822-35830 VB denotes purified
T18828 35819-35821 IN denotes of
T18827 35810-35818 NN denotes extracts
T18826 35802-35809 JJ denotes Nuclear
T18825 35800-35801 -RRB- denotes )
T18824 35796-35800 NN denotes EMSA
T18823 35795-35796 -LRB- denotes (
T18822 35788-35794 NN denotes assays
T18821 35782-35787 NN denotes shift
T18820 35773-35781 NN denotes mobility
T18819 35757-35772 JJ denotes electrophoretic
T18818 35753-35756 CC denotes and
T18817 35744-35752 NN denotes extracts
T18816 35736-35743 JJ denotes nuclear
T18815 35733-35735 IN denotes of
T18405 35327-35336 NN denotes Mutations
T18404 35318-35325 NN denotes control
T18403 35307-35317 JJ denotes additional
T18402 35304-35306 DT denotes an
T18401 35301-35303 IN denotes as
T18400 35296-35300 VB denotes used
T18399 35291-35295 VB denotes were
T18398 35284-35290 NN denotes oligos
T18397 35276-35283 VB denotes mutated
T18396 35274-35275 -COMMA- denotes ,
T18395 35268-35274 NN denotes oligos
T18394 35264-35267 DT denotes the
T18393 35261-35263 IN denotes of
T18392 35249-35260 NN denotes specificity
T18391 35241-35248 NN denotes binding
T18390 35237-35240 DT denotes the
T18389 35232-35236 VB denotes test
T18388 35229-35231 TO denotes To
T18387 35215-35227 NN denotes instructions
T18386 35212-35214 POS denotes 's
T18385 35200-35212 NN denotes manufacturer
T18384 35196-35199 DT denotes the
T18383 35193-35195 TO denotes to
T18382 35183-35192 VB denotes according
T18381 35181-35182 -RRB- denotes )
T18380 35174-35181 NNP denotes Germany
T18075 34741-34744 NN denotes LPS
T18074 34737-34740 CC denotes and
T18073 34734-34736 NN denotes GP
T18072 34731-34733 IN denotes of
T18071 34719-34730 NN denotes combination
T18070 34717-34718 DT denotes a
T18069 34712-34716 IN denotes with
T18068 34709-34711 CC denotes or
T18067 34702-34708 NN denotes TSST-1
T18066 34698-34701 CC denotes and
T18065 34695-34697 NN denotes GP
T18064 34692-34694 IN denotes of
T18063 34680-34691 NN denotes combination
T18062 34678-34679 DT denotes a
T18061 34673-34677 IN denotes with
T18060 34658-34672 RB denotes simultaneously
T18059 34645-34657 VB denotes supplemented
T18058 34640-34644 VB denotes were
T18057 34635-34639 NN denotes PBMC
T18056 34633-34634 -COMMA- denotes ,
T18055 34622-34633 NN denotes experiments
T18054 34608-34621 JJ denotes costimulatory
T18053 34605-34607 IN denotes In
T18052 34602-34603 -RRB- denotes )
T18051 34595-34602 NNP denotes Germany
T18050 34593-34594 -COMMA- denotes ,
T18049 34587-34593 NNP denotes Munich
T18048 34585-34586 -COMMA- denotes ,
T18047 34580-34585 NNP denotes Sigma
T18046 34579-34580 -LRB- denotes (
T18045 34576-34578 NN denotes B4
T17986 34323-34324 -RRB- denotes )
T17985 34316-34323 NNP denotes Germany
T17984 34314-34315 -COMMA- denotes ,
T17983 34304-34314 NNP denotes Heidelberg
T17982 34302-34303 -COMMA- denotes ,
T17981 34296-34302 NNP denotes Falcon
T17980 34295-34296 -LRB- denotes (
T17979 34288-34294 NN denotes plates
T17978 34280-34287 NN denotes culture
T17977 34273-34279 JJ denotes 6-well
T17976 34260-34272 JJ denotes pyrogen-free
T17975 34252-34259 JJ denotes sterile
T17974 34249-34251 IN denotes in
T17973 34246-34248 NN denotes ml
T17972 34244-34245 CD denotes 4
T17971 34241-34243 IN denotes of
T17970 34234-34240 NN denotes volume
T17969 34232-34233 DT denotes a
T17968 34229-34231 IN denotes in
T17967 34220-34228 VB denotes cultured
T17966 34215-34219 VB denotes were
T17965 34210-34214 NN denotes PBMC
T17964 34208-34209 -COMMA- denotes ,
T17963 34199-34208 NN denotes cytokines
T17962 34195-34198 CC denotes and
T17961 34187-34194 NN denotes factors
T17960 34173-34186 NN denotes transcription
T17959 34170-34172 IN denotes of
T17958 34160-34169 NN denotes induction
T17957 34156-34159 IN denotes For
T17956 34145-34155 NN denotes conditions
T17955 34133-34144 NN denotes Stimulation
T18379 35172-35173 -COMMA- denotes ,
T18378 35164-35172 NNP denotes Freiburg
T18377 35162-35163 -COMMA- denotes ,
T18376 35159-35162 NNP denotes LKB
T18375 35149-35158 NNP denotes Pharmacia
T18374 35147-35148 -COMMA- denotes ,
T18373 35144-35147 NN denotes Kit
T18372 35140-35143 NN denotes PNK
T18371 35139-35140 -LRB- denotes (
T18370 35135-35138 NN denotes Kit
T18369 35101-35134 NN denotes Ready-To-Go-Polynucleotide-Kinase
T18368 35097-35100 DT denotes the
T18367 35091-35096 VB denotes using
T18366 35089-35090 -RRB- denotes )
T18365 35082-35089 NNP denotes Germany
T18364 35080-35081 -COMMA- denotes ,
T18363 35068-35080 NNP denotes Braunschweig
T18362 35066-35067 -COMMA- denotes ,
T18361 35058-35066 NNP denotes Amersham
T18360 35056-35057 -COMMA- denotes ,
T18359 35049-35056 NN denotes Ci/mmol
T18358 35043-35048 CD denotes 3,000
T18357 35042-35043 -LRB- denotes (
T18356 35032-35041 NN denotes 5'γ-P-ATP
T18355 35027-35031 IN denotes with
T18354 35015-35026 JJ denotes 32P-labeled
T18353 35011-35014 CC denotes and
T18352 35009-35010 -RRB- denotes )
T18351 35002-35009 NNP denotes Germany
T18350 35000-35001 -COMMA- denotes ,
T18349 34994-35000 NNP denotes Berlin
T18348 34992-34993 -COMMA- denotes ,
T18347 34985-34992 NNP denotes Molbiol
T18346 34981-34984 NNP denotes TIB
T18345 34980-34981 -LRB- denotes (
T18344 34978-34979 -COMMA- denotes ,
T18343 34977-34978 -RRB- denotes )
T18342 34976-34977 CD denotes 1
T18341 34970-34975 JJ denotes Table
T18340 34967-34969 IN denotes in
T18339 34955-34966 VB denotes illustrated
T18338 34954-34955 -LRB- denotes (
T18337 34947-34953 NN denotes oligos
T18336 34945-34946 -RRB- denotes )
T18335 34943-34945 NN denotes ss
T18334 34942-34943 -LRB- denotes (
T18333 34933-34941 JJ denotes stranded
T18332 34926-34932 JJ denotes single
T18331 34921-34925 IN denotes from
T18330 34909-34920 VB denotes synthesised
T18329 34904-34908 VB denotes were
T18328 34894-34903 NN denotes promoters
T18327 34889-34893 NN denotes IL-6
T18326 34885-34888 CC denotes and
T18325 34880-34884 NN denotes IFNγ
T18324 34878-34879 -COMMA- denotes ,
T18323 34874-34878 NN denotes IL-8
T18322 34872-34873 -COMMA- denotes ,
T18321 34868-34872 NN denotes TNFα
T18320 34864-34867 DT denotes the
T18319 34859-34863 IN denotes from
T18318 34857-34858 -RRB- denotes )
T18317 34851-34857 NN denotes oligos
T18316 34850-34851 -LRB- denotes (
T18315 34833-34849 NN denotes oligonucleotides
T18314 34831-34832 -RRB- denotes )
T18313 34829-34831 NN denotes ds
T18312 34828-34829 -LRB- denotes (
T18311 34812-34827 JJ denotes double-stranded
T18310 34798-34811 JJ denotes complementary
T18309 34794-34797 DT denotes The
T18308 34777-34793 JJ denotes 5'-32-P-Labeling
T18307 34773-34776 CC denotes and
T18306 34771-34772 -RRB- denotes )
T18305 34765-34771 NN denotes Oligos
T18304 34764-34765 -LRB- denotes (
T17769 34117-34129 NN denotes BioWhittaker
T17768 34116-34117 -LRB- denotes (
T17767 34104-34115 NN denotes L-glutamine
T17766 34101-34103 NN denotes mM
T17765 34097-34100 CD denotes 200
T17764 34095-34096 NN denotes %
T17763 34094-34095 CD denotes 1
T17762 34090-34093 CC denotes and
T17761 34088-34089 -COMMA- denotes ,
T17760 34087-34088 -RRB- denotes )
T17759 34082-34087 NN denotes μg/ml
T17758 34076-34081 CD denotes 10000
T17757 34075-34076 -LRB- denotes (
T17756 34062-34074 NN denotes streptomycin
T17755 34060-34061 NN denotes %
T17754 34059-34060 CD denotes 1
T17753 34057-34058 -COMMA- denotes ,
T17752 34056-34057 -RRB- denotes )
T17751 34052-34056 NN denotes U/ml
T17750 34046-34051 CD denotes 10000
T17749 34045-34046 -LRB- denotes (
T17748 34034-34044 NN denotes penicillin
T17747 34032-34033 NN denotes %
T17746 34031-34032 CD denotes 1
T17745 34029-34030 -COMMA- denotes ,
T17744 34028-34029 -RRB- denotes )
T17743 34021-34028 NNP denotes Germany
T17742 34019-34020 -COMMA- denotes ,
T17741 34010-34019 NNP denotes Karlsruhe
T17740 34008-34009 -COMMA- denotes ,
T17739 33998-34008 NNP denotes Invitrogen
T17738 33996-33997 -COMMA- denotes ,
T17737 33989-33996 NN denotes low-LPS
T17736 33987-33988 -COMMA- denotes ,
T17735 33984-33987 NN denotes FCS
T17734 33983-33984 -LRB- denotes (
T17733 33977-33982 NN denotes serum
T17732 33972-33976 NN denotes calf
T17731 33966-33971 JJ denotes fetal
T17730 33949-33965 JJ denotes heat-inactivated
T17729 33947-33948 NN denotes %
T17728 33945-33947 CD denotes 10
T17727 33934-33944 VB denotes containing
T17726 33932-33933 -COMMA- denotes ,
T17725 33931-33932 -RRB- denotes )
T17724 33923-33931 JJ denotes LPS-free
T17723 33921-33922 -COMMA- denotes ,
T17722 33914-33921 NNP denotes Germany
T17721 33912-33913 -COMMA- denotes ,
T17720 33902-33912 NNP denotes Heidelberg
T17719 33900-33901 -COMMA- denotes ,
T17718 33888-33900 NNP denotes BioWhittaker
T17717 33887-33888 -LRB- denotes (
T17716 33880-33886 NN denotes medium
T17715 33875-33879 CD denotes 1640
T17714 33870-33874 NN denotes RPMI
T17713 33867-33869 IN denotes in
T17712 33865-33866 -RRB- denotes )
T17711 33856-33865 NN denotes cytometry
T17710 33851-33855 NN denotes flow
T17709 33847-33850 IN denotes for
T17708 33846-33847 -LRB- denotes (
T17707 33837-33845 NN denotes cells/ml
T17706 33833-33836 CD denotes 106
T17705 33831-33832 CC denotes ×
T17704 33829-33830 CD denotes 1
T17703 33826-33828 CC denotes or
T17702 33824-33825 -RRB- denotes )
T17701 33818-33824 NN denotes shifts
T17700 33814-33817 NN denotes gel
T17699 33810-33813 IN denotes for
T17698 33809-33810 -LRB- denotes (
T17697 33802-33808 NN denotes 106/ml
T17696 33800-33801 CC denotes ×
T17695 33798-33799 CD denotes 5
T17694 33795-33797 CC denotes or
T17693 33793-33794 -RRB- denotes )
T17692 33781-33793 NN denotes measurements
T17691 33775-33780 NN denotes ELISA
T17690 33771-33774 IN denotes for
T17689 33770-33771 -LRB- denotes (
T17688 33761-33769 NN denotes cells/ml
T17687 33757-33760 CD denotes 106
T17686 33755-33756 -COLON- denotes ×
T17685 33753-33754 CD denotes 3
T17684 33750-33752 IN denotes of
T17683 33736-33749 NN denotes concentration
T17682 33730-33735 JJ denotes final
T17681 33728-33729 DT denotes a
T17680 33725-33727 IN denotes at
T17679 33716-33724 VB denotes cultured
T17678 33711-33715 VB denotes were
T17677 33706-33710 NN denotes PBMC
T17676 33704-33705 -COMMA- denotes ,
T17675 33695-33704 NN denotes isolation
T17674 33685-33694 VB denotes Following
T17673 33682-33683 -RRB- denotes ]
T17672 33677-33682 CD denotes 54,55
T17671 33676-33677 -LRB- denotes [
T17670 33667-33675 NN denotes gradient
T17669 33665-33666 -RRB- denotes )
T17668 33658-33665 NNP denotes Germany
T17667 33656-33657 -COMMA- denotes ,
T17666 33650-33656 NNP denotes Berlin
T17665 33648-33649 -COMMA- denotes ,
T17664 33640-33648 NNP denotes Biochrom
T17663 33639-33640 -LRB- denotes (
T17662 33624-33638 JJ denotes Ficoll-Hypaque
T17661 33622-33623 DT denotes a
T17660 33617-33621 IN denotes over
T17659 33607-33616 VB denotes separated
T17658 33602-33606 VB denotes were
T17657 33596-33601 NN denotes coats
T17656 33590-33595 NN denotes buffy
T17655 33586-33589 DT denotes The
T17654 33577-33585 NNP denotes Luebeck.
T17653 33574-33576 IN denotes of
T17652 33563-33573 NNP denotes University
T17651 33559-33562 DT denotes the
T17650 33556-33558 IN denotes of
T17649 33546-33555 NN denotes committee
T17648 33539-33545 NN denotes ethics
T17647 33535-33538 DT denotes the
T17646 33532-33534 IN denotes of
T17645 33523-33531 NN denotes approval
T17644 33519-33522 DT denotes the
T17643 33514-33518 IN denotes with
T17642 33510-33513 CC denotes and
T17641 33498-33509 NN denotes declaration
T17640 33489-33497 NNP denotes Helsinki
T17639 33485-33488 DT denotes the
T17638 33480-33484 IN denotes with
T17637 33469-33479 NN denotes compliance
T17636 33466-33468 IN denotes in
T17635 33459-33465 NN denotes donors
T17634 33453-33458 NN denotes blood
T17633 33445-33452 JJ denotes healthy
T17632 33440-33444 IN denotes from
T17631 33431-33439 VB denotes obtained
T17630 33426-33430 VB denotes were
T17629 33420-33425 NN denotes coats
T17628 33414-33419 JJ denotes Buffy
T17627 33409-33413 NN denotes PBMC
T17626 33403-33408 JJ denotes human
T17625 33400-33402 IN denotes of
T17624 33390-33399 NN denotes Isolation
T18044 34575-34576 -COLON- denotes :
T18043 34571-34575 CD denotes 0111
T18042 34562-34570 NN denotes serotype
T18041 34557-34561 FW denotes coli
T18040 34545-34556 FW denotes Escherichia
T18039 34540-34544 IN denotes from
T18038 34536-34539 NN denotes LPS
T18037 34526-34535 JJ denotes wild-type
T18036 34520-34525 NN denotes cells
T18035 34513-34519 NN denotes ng/106
T18034 34509-34512 CD denotes 250
T18033 34504-34508 IN denotes with
T18032 34501-34503 CC denotes or
T18031 34499-34500 -RRB- denotes )
T18030 34496-34499 NNP denotes USA
T18029 34494-34495 -COMMA- denotes ,
T18028 34492-34494 NNP denotes FL
T18027 34490-34491 -COMMA- denotes ,
T18026 34482-34490 NNP denotes Sarasota
T18025 34480-34481 -COMMA- denotes ,
T18024 34468-34480 NNP denotes Technologies
T18023 34462-34467 NNP denotes Toxin
T18022 34461-34462 -LRB- denotes (
T18021 34454-34460 NN denotes TSST-1
T18020 34448-34453 NN denotes cells
T18019 34441-34447 NN denotes ng/106
T18018 34437-34440 CD denotes 250
T18017 34432-34436 IN denotes with
T18016 34430-34431 -COMMA- denotes ,
T18015 34428-34430 NN denotes GP
T18014 34425-34427 IN denotes of
T18013 34419-34424 NN denotes cells
T18012 34415-34418 CD denotes 106
T18011 34411-34414 IN denotes per
T18010 34408-34410 NN denotes μg
T18009 34404-34407 CD denotes 100
T18008 34401-34403 CC denotes or
T18007 34399-34400 CD denotes 1
T18006 34394-34398 IN denotes with
T18005 34392-34393 -RRB- denotes )
T18004 34387-34392 NN denotes ELISA
T18003 34386-34387 -LRB- denotes (
T18002 34384-34385 NN denotes h
T18001 34381-34383 CD denotes 48
T18000 34378-34380 TO denotes to
T17999 34376-34377 NN denotes h
T17998 34374-34375 CD denotes 0
T17997 34369-34373 IN denotes from
T17996 34366-34368 CC denotes or
T17995 34364-34365 -RRB- denotes )
T17994 34360-34364 NN denotes EMSA
T17993 34359-34360 -LRB- denotes (
T17992 34357-34358 NN denotes h
T17991 34355-34356 CD denotes 1
T17990 34351-34354 IN denotes for
T17989 34340-34350 VB denotes stimulated
T17988 34335-34339 VB denotes were
T17987 34326-34334 NN denotes Cultures
T17535 33372-33387 NN denotes β-1→3-D-glucans
T17534 33369-33371 TO denotes to
T17533 33361-33368 VB denotes respond
T17532 33357-33360 RB denotes not
T17531 33352-33356 VB denotes does
T17530 33348-33351 CC denotes but
T17529 33338-33347 NN denotes endotoxin
T17528 33334-33337 IN denotes for
T17527 33325-33333 JJ denotes specific
T17526 33322-33324 VB denotes is
T17525 33316-33321 WDT denotes which
T17524 33314-33315 -COMMA- denotes ,
T17523 33313-33314 -RRB- denotes )
T17522 33308-33313 NNP denotes Japan
T17521 33306-33307 -COMMA- denotes ,
T17520 33301-33306 NNP denotes Tokyo
T17519 33299-33300 -COMMA- denotes ,
T17518 33290-33299 NNP denotes Seigakaku
T17517 33289-33290 -LRB- denotes (
T17516 33283-33288 NN denotes assay
T17515 33273-33282 NN denotes Endospecy
T17514 33269-33272 DT denotes the
T17513 33264-33268 IN denotes with
T17512 33250-33263 NN denotes contamination
T17511 33240-33249 NN denotes endotoxin
T17510 33236-33239 IN denotes for
T17509 33227-33235 VB denotes screened
T17508 33223-33226 CC denotes and
T17507 33221-33222 -RRB- denotes )
T17506 33219-33221 NN denotes μm
T17505 33215-33218 CD denotes 0.2
T17504 33214-33215 -LRB- denotes (
T17503 33196-33213 JJ denotes filter-sterilized
T17502 33194-33195 -COMMA- denotes ,
T17501 33189-33194 NN denotes media
T17500 33181-33188 JJ denotes aqueous
T17499 33178-33180 IN denotes in
T17498 33168-33177 VB denotes dissolved
T17497 33164-33167 VB denotes was
T17496 33161-33163 NN denotes GP
T17495 33158-33159 -RRB- denotes ]
T17494 33153-33158 CD denotes 20,26
T17493 33152-33153 -LRB- denotes [
T17492 33141-33151 RB denotes previously
T17491 33132-33140 VB denotes reported
T17490 33129-33131 IN denotes as
T17489 33118-33128 VB denotes determined
T17488 33113-33117 VB denotes were
T17487 33110-33112 NN denotes GP
T17486 33107-33109 IN denotes of
T17485 33091-33106 NN denotes characteristics
T17484 33075-33090 JJ denotes physicochemical
T17483 33071-33074 DT denotes The
T17482 33068-33069 -RRB- denotes ]
T17481 33066-33068 CD denotes 20
T17480 33065-33066 -LRB- denotes [
T17479 33058-33064 IN denotes before
T17478 33053-33057 VB denotes done
T17477 33050-33052 IN denotes as
T17476 33041-33049 VB denotes prepared
T17475 33037-33040 VB denotes was
T17474 33035-33036 -RRB- denotes )
T17473 33033-33035 NN denotes GP
T17472 33032-33033 -LRB- denotes (
T17471 33017-33031 NN denotes β-1→3-D-glucan
T17470 33002-33016 VB denotes phosphorylated
T17469 32994-33001 JJ denotes soluble
T17468 32988-32993 RB denotes Water
T17467 32978-32987 NN denotes Materials
T17770 34129-34130 -RRB- denotes )
T17163 32389-32397 RB denotes moreover
T17250 32965-32966 -RRB- denotes ]
T17249 32960-32965 CD denotes 52,53
T17248 32959-32960 -LRB- denotes [
T17247 32953-32958 NN denotes ratio
T17246 32940-32952 NN denotes IL-1β/IL-1RA
T17245 32927-32939 VB denotes dysregulated
T17244 32925-32926 DT denotes a
T17243 32920-32924 IN denotes with
T17242 32909-32919 RB denotes especially
T17241 32907-32908 -COMMA- denotes ,
T17240 32897-32907 NN denotes conditions
T17239 32880-32896 JJ denotes pro-inflammatory
T17238 32877-32879 IN denotes in
T17237 32867-32876 NN denotes phosphate
T17236 32860-32866 NN denotes glucan
T17235 32857-32859 IN denotes by
T17234 32848-32856 VB denotes mediated
T17233 32840-32847 NN denotes effects
T17232 32829-32839 JJ denotes protective
T17231 32826-32828 IN denotes of
T17230 32818-32825 NN denotes concept
T17229 32814-32817 DT denotes the
T17228 32806-32813 VB denotes support
T17227 32800-32805 MD denotes might
T17226 32791-32799 NN denotes findings
T17225 32787-32790 PRP-DOLLAR- denotes our
T17224 32785-32786 -COMMA- denotes ,
T17223 32784-32785 -RRB- denotes ]
T17222 32779-32784 CD denotes 22,37
T17221 32778-32779 -LRB- denotes [
T17220 32770-32777 NN denotes studies
T17219 32765-32769 FW denotes vivo
T17218 32762-32764 FW denotes in
T17217 32758-32761 DT denotes the
T17216 32753-32757 IN denotes with
T17215 32744-32752 RB denotes Together
T17214 32730-32742 NN denotes carbohydrate
T17213 32723-32729 JJ denotes fungal
T17212 32721-32722 DT denotes a
T17211 32718-32720 IN denotes by
T17210 32703-32717 RB denotes differentially
T17209 32693-32702 VB denotes regulated
T17208 32690-32692 VB denotes be
T17207 32686-32689 MD denotes can
T17206 32680-32685 WDT denotes which
T17205 32678-32679 -COMMA- denotes ,
T17204 32677-32678 -RRB- denotes )
T17203 32676-32677 CD denotes 8
T17202 32671-32675 NN denotes Fig.
T17201 32670-32671 -LRB- denotes (
T17200 32661-32669 NN denotes promoter
T17199 32654-32660 NN denotes IL-1RA
T17198 32650-32653 DT denotes the
T17197 32647-32649 IN denotes in
T17196 32641-32646 NN denotes sites
T17195 32630-32640 VB denotes identified
T17194 32624-32629 RB denotes newly
T17193 32620-32623 CC denotes and
T17192 32614-32619 VB denotes known
T17191 32606-32613 JJ denotes various
T17190 32603-32605 TO denotes to
T17189 32595-32602 VB denotes binding
T17188 32588-32594 NN denotes factor
T17187 32574-32587 NN denotes transcription
T17186 32571-32573 IN denotes of
T17185 32561-32570 NN denotes interplay
T17184 32553-32560 JJ denotes complex
T17183 32548-32552 RB denotes very
T17182 32546-32547 DT denotes a
T17181 32541-32545 IN denotes into
T17180 32532-32540 NN denotes insights
T17179 32528-32531 JJ denotes new
T17178 32518-32527 VB denotes generated
T17177 32513-32517 RB denotes also
T17176 32505-32512 NN denotes results
T17175 32501-32504 PRP-DOLLAR- denotes Our
T17174 32491-32499 NN denotes reaction
T17173 32473-32490 JJ denotes anti-inflammatory
T17172 32457-32472 JJ denotes IL-1RA-mediated
T17171 32454-32456 DT denotes an
T17170 32451-32453 TO denotes to
T17169 32442-32450 NN denotes response
T17168 32427-32441 JJ denotes TSST-1-induced
T17167 32410-32426 JJ denotes pro-inflammatory
T17166 32408-32409 DT denotes a
T17165 32399-32407 VB denotes switched
T17164 32397-32398 -COMMA- denotes ,
T17162 32387-32388 -COMMA- denotes ,
T17161 32384-32387 CC denotes and
T17160 32377-32383 NN denotes TSST-1
T17159 32372-32376 IN denotes from
T17158 32367-32371 RB denotes also
T17157 32363-32366 CC denotes and
T17156 32359-32362 NN denotes LPS
T17155 32354-32358 IN denotes from
T17154 32344-32353 JJ denotes different
T17153 32336-32343 NN denotes profile
T17152 32327-32335 NN denotes cytokine
T17151 32316-32326 JJ denotes subsequent
T17150 32314-32315 DT denotes a
T17149 32310-32313 CC denotes and
T17148 32302-32309 NN denotes binding
T17147 32295-32301 NN denotes factor
T17146 32281-32294 NN denotes transcription
T17145 32279-32280 DT denotes a
T17144 32271-32278 VB denotes induced
T17143 32261-32270 NN denotes phosphate
T17142 32254-32260 NN denotes glucan
T17141 32248-32253 FW denotes vitro
T17140 32245-32247 FW denotes in
T17139 32240-32244 IN denotes that
T17138 32227-32239 VB denotes demonstrated
T17137 32222-32226 NN denotes data
T17136 32218-32221 PRP-DOLLAR- denotes our
T17135 32216-32217 -COMMA- denotes ,
T17134 32209-32216 NN denotes summary
T17133 32206-32208 IN denotes In
T14240 32189-32191 CD denotes 51
T14239 32188-32189 -LRB- denotes [
T14238 32182-32187 NN denotes parts
T14237 32178-32181 DT denotes all
T14236 32175-32177 IN denotes in
T14235 32164-32174 JJ denotes equivalent
T14234 32160-32163 RB denotes not
T14233 32156-32159 VB denotes are
T14232 32150-32155 WDT denotes which
T14231 32142-32149 NN denotes signals
T14230 32139-32141 IN denotes of
T14229 32128-32138 JJ denotes suggestive
T14228 32126-32127 -COMMA- denotes ,
T14227 32115-32126 NN denotes combination
T14226 32112-32114 IN denotes in
T14225 32096-32111 RB denotes synergistically
T14224 32090-32095 VB denotes acted
T14223 32086-32089 CC denotes and
T14222 32077-32085 NN denotes proteins
T14221 32054-32076 JJ denotes mechanisms/DNA-binding
T14220 32044-32053 JJ denotes different
T14219 32036-32043 IN denotes through
T14218 32031-32035 NN denotes gene
T14217 32024-32030 NN denotes IL-1RA
T14216 32020-32023 DT denotes the
T14215 32010-32019 VB denotes activated
T14214 31996-32009 NN denotes peptidoglycan
T14213 31992-31995 CC denotes and
T14212 31988-31991 NN denotes LPS
T14211 31986-31987 -COMMA- denotes ,
T14210 31983-31986 NN denotes PRR
T14209 31975-31982 JJ denotes similar
T14208 31972-31974 IN denotes of
T14207 31968-31971 NN denotes use
T14206 31964-31967 DT denotes the
T14205 31956-31963 IN denotes despite
T14204 31951-31955 IN denotes that
T14203 31943-31950 VB denotes showing
T14202 31937-31942 NN denotes study
T14201 31929-31936 DT denotes another
T14200 31926-31928 IN denotes by
T14199 31916-31925 VB denotes supported
T14198 31913-31915 VB denotes be
T14197 31909-31912 MD denotes may
T14196 31904-31908 NN denotes idea
T14195 31899-31903 DT denotes This
T14194 31896-31897 -RRB- denotes )
T14193 31887-31896 NN denotes signaling
T14192 31880-31886 NN denotes kinase
T14191 31862-31879 JJ denotes mitogen-activated
T14190 31861-31862 -LRB- denotes (
T14189 31857-31860 NN denotes LPS
T14188 31853-31856 CC denotes and
T14187 31851-31852 -RRB- denotes )
T14186 31847-31851 NN denotes PI3K
T14185 31846-31847 -LRB- denotes (
T14184 31843-31845 NN denotes GP
T14183 31835-31842 IN denotes between
T14182 31825-31834 NN denotes signaling
T14181 31822-31824 IN denotes in
T14180 31811-31821 NN denotes difference
T14179 31809-31810 DT denotes a
T14178 31805-31808 IN denotes for
T14177 31793-31804 NN denotes explanation
T14176 31790-31792 DT denotes an
T14175 31784-31789 VB denotes offer
T14174 31780-31783 MD denotes may
T14158 31715-31717 CD denotes 49
T14157 31714-31715 -LRB- denotes [
T14156 31708-31713 NN denotes cells
T14155 31706-31707 NN denotes T
T14154 31703-31705 IN denotes in
T14153 31698-31702 NN denotes NFAT
T14152 31695-31697 IN denotes of
T14151 31684-31694 NN denotes activation
T14150 31680-31683 DT denotes the
T14149 31677-31679 IN denotes in
T14148 31668-31676 VB denotes involved
T14147 31665-31667 VB denotes be
T14146 31662-31664 TO denotes to
T14145 31653-31661 VB denotes reported
T14144 31648-31652 VB denotes been
T14143 31644-31647 VB denotes has
T14142 31639-31643 NN denotes PI3K
T14141 31635-31638 IN denotes via
T14140 31625-31634 NN denotes Signaling
T14139 31622-31623 -RRB- denotes ]
T14138 31620-31622 CD denotes 48
T14137 31619-31620 -LRB- denotes [
T14136 31608-31618 NN denotes production
T14135 31602-31607 NN denotes IL-1β
T14134 31598-31601 RB denotes not
T14133 31594-31597 CC denotes but
T14132 31586-31593 NN denotes sIL-1RA
T14131 31577-31585 VB denotes controls
T14130 31565-31576 RB denotes selectively
T14129 31557-31564 NN denotes pathway
T14128 31552-31556 NN denotes PI3K
T14127 31548-31551 DT denotes the
T14126 31537-31547 NN denotes leukocytes
T14125 31518-31536 JJ denotes septic/LPS-adapted
T14124 31515-31517 IN denotes in
T14123 31510-31514 IN denotes that
T14122 31497-31509 VB denotes demonstrated
T14121 31492-31496 VB denotes been
T14120 31488-31491 VB denotes has
T14119 31485-31487 PRP denotes It
T14118 31482-31483 -RRB- denotes ]
T14117 31477-31482 CD denotes 22,37
T14116 31476-31477 -LRB- denotes [
T14115 31466-31475 NN denotes treatment
T14114 31463-31465 NN denotes GP
T14113 31460-31462 IN denotes by
T14112 31450-31459 VB denotes sustained
T14111 31447-31449 VB denotes be
T14110 31443-31446 MD denotes may
T14109 31436-31442 NN denotes effect
T14108 31431-31435 DT denotes this
T14107 31427-31430 CC denotes and
T14106 31425-31426 -RRB- denotes ]
T14105 31423-31425 CD denotes 44
T14104 31422-31423 -LRB- denotes [
T14103 31412-31421 NN denotes signaling
T14102 31408-31411 IN denotes for
T14101 31400-31407 NN denotes pathway
T14100 31395-31399 NN denotes PI3K
T14099 31391-31394 DT denotes the
T13995 30800-30804 IN denotes over
T13994 30793-30799 NN denotes IL-1RA
T13993 30790-30792 IN denotes of
T13992 30783-30789 NN denotes excess
T13956 30580-30584 IN denotes that
T13955 30574-30579 VB denotes think
T13991 30775-30782 JJ denotes 100fold
T13990 30773-30774 DT denotes a
T13989 30767-30772 FW denotes vitro
T13988 30764-30766 FW denotes in
T13987 30759-30763 IN denotes that
T13986 30748-30758 VB denotes postulated
T13985 30743-30747 VB denotes been
T13984 30739-30742 VB denotes has
T13983 30736-30738 PRP denotes it
T13982 30734-30735 -COMMA- denotes ,
T13981 30727-30734 NN denotes context
T13980 30722-30726 DT denotes this
T13979 30719-30721 IN denotes In
T13978 30716-30717 -RRB- denotes )
T13977 30715-30716 CD denotes 6
T13976 30710-30714 NN denotes Fig.
T13975 30709-30710 -LRB- denotes (
T13974 30702-30708 NN denotes TSST-1
T13973 30700-30701 SYM denotes +
T13972 30697-30699 NN denotes GP
T13971 30687-30696 VB denotes following
T13970 30681-30686 NN denotes ratio
T13969 30668-30680 NN denotes IL-1β/IL-1RA
T13968 30664-30667 DT denotes the
T13967 30661-30663 IN denotes of
T13966 30652-30660 NN denotes decrease
T13965 30648-30651 DT denotes the
T13964 30645-30647 IN denotes by
T13963 30635-30644 VB denotes reflected
T13962 30631-30634 VB denotes was
T13961 30617-30630 NN denotes transcription
T13960 30614-30616 IN denotes of
T13959 30603-30613 NN denotes activation
T13958 30590-30602 JJ denotes GP-modulated
T13957 30585-30589 DT denotes this
T13954 30571-30573 PRP denotes We
T13953 30559-30569 NN denotes production
T13952 30552-30558 NN denotes IL-1RA
T13951 30537-30551 JJ denotes TSST-1-induced
T13950 30533-30536 DT denotes the
T13949 30530-30532 IN denotes of
T13948 30516-30529 NN denotes up-regulation
T13947 30504-30515 JJ denotes synergistic
T13946 30500-30503 DT denotes the
T13945 30492-30499 VB denotes explain
T13944 30488-30491 MD denotes may
T13943 30483-30487 NN denotes site
T13942 30474-30482 NN denotes NFATP2/3
T13941 30468-30473 JJ denotes novel
T13940 30464-30467 DT denotes the
T13939 30461-30463 TO denotes to
T13938 30458-30460 IN denotes as
T13937 30453-30457 RB denotes well
T13936 30450-30452 RB denotes as
T13935 30448-30449 -RRB- denotes ]
T13934 30446-30448 CD denotes 32
T13933 30445-30446 -LRB- denotes [
T13932 30440-30444 NN denotes site
T13931 30433-30439 NN denotes NFIL-6
T13930 30429-30432 DT denotes the
T13929 30427-30428 -COMMA- denotes ,
T13928 30423-30427 NN denotes site
T13927 30413-30422 NN denotes consensus
T13926 30408-30412 NN denotes NFκB
T13925 30404-30407 CC denotes and
T13924 30398-30403 NN denotes NFκB3
T13923 30394-30397 JJ denotes new
T13922 30390-30393 DT denotes the
T13921 30387-30389 TO denotes to
T13920 30379-30386 NN denotes binding
T13919 30364-30378 JJ denotes TSST-1-induced
T13918 30361-30363 IN denotes in
T13917 30352-30360 NN denotes increase
T13916 30339-30351 JJ denotes GP-modulated
T13915 30335-30338 DT denotes The
T13914 30332-30333 -RRB- denotes ]
T13913 30330-30332 CD denotes 30
T13912 30329-30330 -LRB- denotes [
T13911 30321-30328 NN denotes element
T13910 30310-30320 JJ denotes inhibitory
T13909 30300-30309 VB denotes described
T13908 30289-30299 JJ denotes previoulsy
T13907 30285-30288 DT denotes the
T13906 30282-30284 IN denotes of
T13905 30277-30281 NN denotes part
T13904 30275-30276 DT denotes a
T13903 30269-30274 JJ denotes least
T13902 30266-30268 IN denotes at
T13901 30256-30265 VB denotes represent
T13900 30246-30255 RB denotes therefore
T13899 30242-30245 MD denotes may
T13898 30237-30241 NN denotes site
T13897 30232-30236 DT denotes this
T13896 30230-30231 -COMMA- denotes ,
T13895 30223-30230 NN denotes opinion
T13894 30219-30222 PRP-DOLLAR- denotes our
T13893 30216-30218 IN denotes In
T13892 30212-30214 NN denotes GP
T13891 30209-30211 IN denotes by
T13890 30201-30208 VB denotes altered
T13889 30198-30200 VB denotes be
T13888 30194-30197 RB denotes not
T13887 30188-30193 MD denotes could
T13886 30182-30187 WDT denotes which
T13885 30180-30181 -COMMA- denotes ,
T13884 30173-30180 NN denotes binding
T13883 30158-30172 JJ denotes TSST-1-induced
T13882 30154-30157 CC denotes and
T13881 30149-30153 NN denotes LPS-
T13880 30145-30148 DT denotes the
T13879 30142-30144 IN denotes of
T13878 30125-30141 NN denotes down-regulations
T13877 30111-30124 VB denotes demonstrating
T13876 30109-30110 -COMMA- denotes ,
T13875 30102-30109 NN denotes element
T13874 30091-30101 JJ denotes inhibitory
T13873 30087-30090 DT denotes the
T13872 30084-30086 IN denotes of
T13871 30080-30083 NN denotes end
T13870 30076-30079 DT denotes the
T13869 30068-30075 IN denotes towards
T13868 30066-30067 -RRB- denotes )
T13867 30062-30066 CD denotes -302
T13866 30058-30061 CC denotes and
T13865 30053-30057 CD denotes -288
T13864 30052-30053 -LRB- denotes (
T13863 30047-30051 NN denotes site
T13862 30039-30046 NN denotes NFκB2/3
T13861 30028-30038 JJ denotes inhibitory
T13860 30025-30027 DT denotes an
T13859 30019-30024 VB denotes found
T13858 30016-30018 PRP denotes we
T13857 30014-30015 -COMMA- denotes ,
T13856 30010-30014 NN denotes side
T13855 30004-30009 JJ denotes other
T13854 30000-30003 DT denotes the
T13853 29997-29999 IN denotes On
T13852 29985-29995 NN denotes inhibition
T13851 29982-29984 DT denotes no
T13850 29973-29981 VB denotes observed
T13849 29970-29972 PRP denotes we
T13848 29968-29969 -COMMA- denotes ,
T13847 29967-29968 -RRB- denotes ]
T13846 29965-29967 CD denotes 30
T13845 29964-29965 -LRB- denotes [
T13844 29955-29963 NN denotes promoter
T13843 29948-29954 NN denotes IL-1RA
T13842 29944-29947 DT denotes the
T13841 29941-29943 IN denotes of
T13840 29939-29940 -RRB- denotes )
T13839 29935-29939 CD denotes -294
T13838 29931-29934 CC denotes and
T13837 29926-29930 CD denotes -250
T13836 29925-29926 -LRB- denotes (
T13835 29917-29924 NN denotes element
T13834 29906-29916 JJ denotes inhibitory
T13833 29902-29905 DT denotes the
T13832 29899-29901 IN denotes in
T13831 29897-29898 -RRB- denotes )
T13830 29893-29897 CD denotes -280
T13829 29889-29892 CC denotes and
T13828 29884-29888 CD denotes -266
T13827 29883-29884 -LRB- denotes (
T13826 29878-29882 NN denotes site
T13825 29868-29877 NN denotes consensus
T13824 29863-29867 NN denotes NFκB
T13823 29859-29862 JJ denotes new
T13822 29855-29858 DT denotes the
T13821 29852-29854 IN denotes of
T13820 29843-29851 NN denotes location
T13819 29839-29842 DT denotes the
T13818 29831-29838 IN denotes Despite
T13817 29828-29829 -RRB- denotes ]
T13816 29823-29828 CD denotes 41,42
T13815 29822-29823 -LRB- denotes [
T13814 29814-29821 NN denotes binding
T13813 29811-29813 IN denotes in
T13812 29799-29810 NN denotes differences
T13811 29796-29798 TO denotes to
T13810 29788-29795 VB denotes leading
T13809 29779-29787 RB denotes probably
T13808 29777-29778 -COMMA- denotes ,
T13807 29776-29777 -RRB- denotes )
T13806 29775-29776 CD denotes 1
T13805 29769-29774 JJ denotes Table
T13804 29765-29768 VB denotes see
T13803 29763-29764 -COMMA- denotes ,
T13802 29758-29763 NN denotes motif
T13801 29753-29757 NN denotes TNFα
T13800 29749-29752 DT denotes the
T13799 29746-29748 IN denotes in
T13798 29744-29745 NN denotes C
T13797 29734-29743 VB denotes conserved
T13796 29730-29733 DT denotes the
T13795 29727-29729 IN denotes of
T13794 29719-29726 RB denotes instead
T13793 29716-29718 CD denotes 10
T13792 29707-29715 NN denotes position
T13791 29704-29706 IN denotes on
T13790 29702-29703 NN denotes T
T13789 29700-29701 DT denotes a
T13788 29691-29699 VB denotes contains
T13787 29685-29690 NN denotes motif
T13786 29678-29684 NN denotes IL-1RA
T13785 29674-29677 DT denotes the
T13784 29668-29673 NN denotes NFκB3
T13783 29664-29667 IN denotes for
T13782 29663-29664 -LRB- denotes (
T13781 29654-29662 NN denotes promoter
T13780 29647-29653 NN denotes IL-1RA
T13651 28941-28944 DT denotes the
T13650 28938-28940 IN denotes of
T13649 28926-28937 NN denotes enhancement
T13648 28914-28925 JJ denotes GP-mediated
T13647 28910-28913 DT denotes the
T13646 28905-28909 IN denotes with
T13645 28894-28904 VB denotes correlated
T13644 28883-28893 RB denotes negatively
T13643 28874-28882 NN denotes promoter
T13642 28869-28873 NN denotes TNFα
T13641 28865-28868 DT denotes the
T13640 28860-28864 IN denotes from
T13639 28854-28859 NN denotes sites
T13638 28851-28853 TO denotes to
T13637 28846-28850 NN denotes NFκB
T13636 28843-28845 IN denotes of
T13635 28835-28842 NN denotes binding
T13634 28820-28834 JJ denotes TSST-1-induced
T13633 28816-28819 DT denotes the
T13632 28811-28815 IN denotes that
T13631 28805-28810 VB denotes found
T13630 28802-28804 PRP denotes we
T13629 28800-28801 -COMMA- denotes ,
T13628 28789-28800 RB denotes Accordingly
T13627 28779-28787 NN denotes promoter
T13626 28774-28778 NN denotes IFNγ
T13625 28771-28773 CC denotes or
T13624 28766-28770 NN denotes IL-6
T13623 28764-28765 -COMMA- denotes ,
T13622 28759-28764 NN denotes IL-1β
T13621 28757-28758 -COMMA- denotes ,
T13620 28753-28757 NN denotes TNFα
T13619 28749-28752 DT denotes the
T13618 28746-28748 IN denotes of
T13617 28738-28745 RB denotes instead
T13616 28729-28737 NN denotes promoter
T13615 28722-28728 NN denotes IL-1RA
T13614 28718-28721 CC denotes and
T13613 28713-28717 NN denotes IL-8
T13612 28709-28712 DT denotes the
T13611 28702-28708 IN denotes within
T13610 28696-28701 NN denotes sites
T13609 28688-28695 JJ denotes unknown
T13608 28684-28687 RB denotes now
T13607 28681-28683 TO denotes to
T13606 28678-28680 IN denotes up
T13605 28674-28677 CC denotes and
T13604 28668-28673 VB denotes known
T13603 28665-28667 TO denotes to
T13602 28660-28664 NN denotes NFAT
T13601 28656-28659 CC denotes and
T13600 28649-28655 NN denotes NFIL-6
T13599 28647-28648 -COMMA- denotes ,
T13598 28643-28647 NN denotes NFκB
T13597 28640-28642 IN denotes of
T13596 28632-28639 NN denotes binding
T13595 28624-28631 VB denotes induced
T13594 28617-28623 NN denotes TSST-1
T13593 28613-28616 DT denotes the
T13592 28610-28612 IN denotes of
T13591 28598-28609 NN denotes modulations
T13590 28586-28597 JJ denotes GP-mediated
T13589 28583-28585 IN denotes by
T13588 28576-28582 VB denotes caused
T13587 28573-28575 VB denotes be
T13586 28569-28572 MD denotes may
T13585 28562-28568 NN denotes change
T13584 28557-28561 DT denotes this
T13583 28555-28556 -COMMA- denotes ,
T13582 28551-28555 NN denotes part
T13581 28548-28550 IN denotes In
T13580 28540-28546 NN denotes IL-1RA
T13579 28537-28539 IN denotes of
T13578 28523-28536 NN denotes up-regulation
T13577 28511-28522 JJ denotes synergistic
T13576 28509-28510 DT denotes a
T13575 28505-28508 VB denotes was
T13574 28499-28504 EX denotes there
T13573 28494-28498 NN denotes time
T13572 28489-28493 JJ denotes same
T13571 28485-28488 DT denotes the
T13570 28482-28484 IN denotes at
T13569 28480-28481 -COMMA- denotes ,
T13568 28476-28480 NN denotes IL-6
T13567 28472-28475 CC denotes and
T13566 28466-28471 NN denotes IL-1β
T13565 28463-28465 IN denotes of
T13564 28447-28462 NN denotes down-regulation
T13563 28443-28446 IN denotes via
T13562 28435-28442 NN denotes profile
T13561 28417-28434 JJ denotes anti-inflammatory
T13560 28414-28416 DT denotes an
T13559 28411-28413 TO denotes to
T13558 28406-28410 NN denotes pro-
T13557 28404-28405 DT denotes a
T13556 28399-28403 IN denotes from
T13555 28393-28398 NN denotes ratio
T13554 28380-28392 NN denotes IL-1β/IL-1RA
T13553 28365-28379 JJ denotes TSST-1-induced
T13552 28361-28364 DT denotes the
T13551 28353-28360 VB denotes altered
T13550 28350-28352 NN denotes GP
T13549 28348-28349 -COMMA- denotes ,
T13548 28342-28348 RB denotes Mainly
T13547 28339-28340 -RRB- denotes ]
T13546 28334-28339 CD denotes 21-24
T13545 28333-28334 -LRB- denotes [
T13544 28320-28332 NN denotes inflammation
T13543 28316-28319 CC denotes and
T13542 28309-28315 NN denotes sepsis
T13541 28306-28308 IN denotes of
T13540 28299-28305 NN denotes models
T13539 28292-28298 JJ denotes murine
T13538 28289-28291 IN denotes in
T13537 28281-28288 NN denotes effects
T13536 28277-28280 DT denotes the
T13535 28274-28276 TO denotes to
T13534 28266-28273 JJ denotes similar
T13533 28264-28265 -COMMA- denotes ,
T13532 28255-28264 NN denotes reactions
T13531 28248-28254 JJ denotes immune
T13530 28231-28247 JJ denotes pro-inflammatory
T13529 28225-28230 PRP-DOLLAR- denotes their
T13528 28213-28224 VB denotes ameliorated
T13527 28210-28212 NN denotes GP
T13526 28208-28209 -COMMA- denotes ,
T13525 28207-28208 -RRB- denotes )
T13524 28201-28207 NN denotes TSST-1
T13523 28198-28200 CC denotes or
T13522 28194-28197 NN denotes LPS
T13521 28193-28194 -LRB- denotes (
T13520 28185-28192 NN denotes stimuli
T13519 28179-28184 JJ denotes other
T13518 28176-28178 IN denotes of
T13517 28167-28175 NN denotes presence
T13516 28163-28166 DT denotes the
T13515 28160-28162 IN denotes in
T13514 28158-28159 -COMMA- denotes ,
T13513 28154-28158 IN denotes that
T13512 28148-28153 VB denotes found
T13511 28145-28147 PRP denotes we
T13510 28143-28144 -COMMA- denotes ,
T13509 28141-28143 NN denotes GP
T13508 28138-28140 IN denotes by
T13507 28130-28137 VB denotes induced
T13506 28124-28129 NN denotes panel
T13505 28115-28123 NN denotes cytokine
T13504 28106-28114 JJ denotes specific
T13503 28102-28105 DT denotes the
T13502 28097-28101 IN denotes than
T13501 28088-28096 JJ denotes relevant
T13500 28083-28087 RB denotes more
T13499 28078-28082 RB denotes even
T13498 28066-28077 RB denotes Potentially
T13497 27817-27823 NN denotes attack
T13496 27807-27816 JJ denotes microbial
T13495 27798-27806 JJ denotes possible
T13494 27796-27797 DT denotes a
T13493 27788-27795 IN denotes against
T13492 27777-27787 NN denotes mechanisms
T13491 27767-27776 JJ denotes defensive
T13490 27758-27766 VB denotes mounting
T13489 27756-27757 -COMMA- denotes ,
T13488 27748-27756 NN denotes response
T13487 27743-27747 NN denotes PAMP
T13486 27736-27742 JJ denotes benign
T13485 27734-27735 DT denotes a
T13484 27731-27733 TO denotes to
T13483 27727-27730 VB denotes fit
T13482 27722-27726 RB denotes well
T13481 27718-27721 MD denotes may
T13480 27716-27717 -RRB- denotes )
T13479 27714-27716 NN denotes GP
T13478 27713-27714 -LRB- denotes (
T13477 27699-27712 NN denotes carbohydrates
T13476 27692-27698 JJ denotes fungal
T13475 27689-27691 IN denotes by
T13474 27682-27688 NN denotes IL-1RA
T13473 27664-27681 JJ denotes anti-inflammatory
T13472 27660-27663 DT denotes the
T13471 27656-27659 CC denotes and
T13470 27651-27655 NN denotes IL-8
T13469 27629-27650 JJ denotes neutrophil-attracting
T13468 27625-27628 DT denotes the
T13467 27622-27624 IN denotes of
T13466 27612-27621 NN denotes induction
T13465 27608-27611 DT denotes the
T13464 27606-27607 -COMMA- denotes ,
T13463 27596-27606 RB denotes Altogether
T13462 27593-27594 -RRB- denotes ]
T14098 31387-31390 VB denotes use
T14097 31384-31386 TO denotes to
T14096 31378-31383 VB denotes shown
T14095 31373-31377 VB denotes been
T14094 31369-31372 VB denotes has
T14093 31362-31368 NN denotes TSST-1
T14092 31359-31360 -RRB- denotes ]
T14091 31354-31359 CD denotes 43-45
T14090 31353-31354 -LRB- denotes [
T14089 31346-31352 NN denotes TSST-1
T14088 31342-31345 CC denotes and
T14087 31338-31341 NN denotes LPS
T14086 31330-31337 IN denotes between
T14085 31321-31329 NN denotes pathways
T14084 31311-31320 NN denotes signaling
T14083 31308-31310 IN denotes in
T14082 31296-31307 NN denotes differences
T14081 31287-31295 JJ denotes balanced
T14080 31276-31286 RB denotes delicately
T14079 31273-31275 TO denotes to
T14078 31262-31272 VB denotes attributed
T14077 31259-31261 VB denotes be
T14076 31255-31258 MD denotes may
T14075 31253-31254 -COMMA- denotes ,
T14074 31248-31253 NN denotes study
T14073 31243-31247 DT denotes this
T14072 31240-31242 IN denotes in
T14071 31231-31239 VB denotes observed
T14070 31222-31230 NN denotes response
T14069 31215-31221 JJ denotes immune
T14068 31203-31214 JJ denotes LPS-induced
T14067 31199-31202 DT denotes the
T14066 31196-31198 IN denotes on
T14065 31193-31195 NN denotes GP
T14064 31190-31192 IN denotes of
T14063 31182-31189 NN denotes effects
T14062 31171-31181 JJ denotes modulating
T14061 31164-31170 JJ denotes weaker
T14060 31160-31163 DT denotes The
T14059 31157-31158 -RRB- denotes )
T14058 31151-31157 NN denotes detail
T14057 31148-31150 IN denotes in
T14056 31142-31147 VB denotes shown
T14055 31138-31141 RB denotes not
T14054 31133-31137 NN denotes data
T14053 31132-31133 -LRB- denotes (
T14052 31126-31131 NN denotes cells
T14051 31121-31125 NN denotes EL-4
T14050 31114-31120 JJ denotes murine
T14049 31111-31113 IN denotes of
T14048 31100-31110 NN denotes production
T14047 31095-31099 NN denotes IL-2
T14046 31080-31094 JJ denotes IL-1-dependent
T14045 31078-31079 -COMMA- denotes ,
T14044 31064-31078 JJ denotes TSST-1-induced
T14043 31060-31063 DT denotes the
T14042 31052-31059 VB denotes reduced
T14041 31049-31051 NN denotes GP
T14040 31047-31048 -COMMA- denotes ,
T14039 31041-31047 RB denotes Indeed
T14038 31033-31039 NN denotes system
T14037 31029-31032 PRP-DOLLAR- denotes our
T14036 31026-31028 IN denotes in
T14035 31014-31025 VB denotes inactivated
T14034 31011-31013 VB denotes is
T14033 30999-31010 NN denotes bioactivity
T14032 30993-30998 NN denotes IL-1β
T14031 30988-30992 IN denotes that
T14030 30981-30987 VB denotes assume
T14029 30978-30980 TO denotes to
T14028 30965-30977 JJ denotes unreasonable
T14027 30961-30964 RB denotes not
T14026 30958-30960 VB denotes is
T14025 30955-30957 PRP denotes it
T14024 30953-30954 -COMMA- denotes ,
T14023 30949-30953 CD denotes 0.01
T14022 30944-30948 IN denotes than
T14021 30939-30943 JJ denotes less
T14020 30929-30938 RB denotes partially
T14019 30926-30928 VB denotes is
T14018 30919-30925 NN denotes TSST-1
T14017 30917-30918 SYM denotes +
T14016 30914-30916 NN denotes GP
T14015 30904-30913 VB denotes following
T14014 30898-30903 NN denotes ratio
T14013 30885-30897 NN denotes IL-1β/IL-1RA
T14012 30881-30884 DT denotes the
T14011 30879-30880 -COMMA- denotes ,
T14010 30875-30879 NN denotes fact
T14009 30872-30874 IN denotes in
T14008 30870-30871 -COMMA- denotes ,
T14007 30865-30870 IN denotes Since
T14006 30862-30863 -RRB- denotes ]
T14005 30857-30862 CD denotes 46,47
T14004 30856-30857 -LRB- denotes [
T14003 30851-30855 NN denotes IL-1
T14002 30848-30850 IN denotes of
T14001 30840-30847 NN denotes effects
T14000 30829-30839 JJ denotes biological
T13999 30825-30828 DT denotes the
T13998 30817-30824 VB denotes control
T13997 30811-30816 MD denotes might
T13996 30805-30810 NN denotes IL-1β
T13461 27588-27593 CD denotes 44,45
T13460 27587-27588 -LRB- denotes [
T13459 27577-27586 NN denotes signaling
T13458 27570-27576 NN denotes kinase
T13457 27552-27569 JJ denotes mitogen-activated
T13456 27548-27551 NN denotes p38
T13455 27544-27547 CC denotes and
T13454 27539-27543 NN denotes PI3K
T13453 27537-27538 -COMMA- denotes ,
T13452 27533-27537 CC denotes both
T13451 27529-27532 IN denotes via
T13450 27522-27528 JJ denotes latter
T13449 27518-27521 DT denotes the
T13448 27516-27517 -COMMA- denotes ,
T13447 27512-27516 NN denotes TNFα
T13446 27508-27511 CC denotes and
T13445 27503-27507 NN denotes IFNγ
T13444 27496-27502 RB denotes mainly
T13443 27493-27495 IN denotes of
T13442 27485-27492 NN denotes release
T13441 27482-27484 TO denotes to
T13440 27474-27481 VB denotes leading
T13439 27472-27473 -COMMA- denotes ,
T13438 27464-27472 NN denotes receptor
T13437 27459-27463 NN denotes cell
T13436 27457-27458 NN denotes T
T13434 27440-27452 RB denotes subsequently
T13433 27436-27439 CC denotes and
T13432 27426-27435 NN denotes molecules
T13431 27419-27425 NN denotes MHC-II
T13430 27416-27418 TO denotes to
T13429 27408-27415 NN denotes binding
T13428 27400-27407 IN denotes through
T13427 27395-27399 VB denotes acts
T13426 27388-27394 NN denotes TSST-1
T13425 27383-27387 IN denotes like
T13424 27370-27382 NN denotes superantigen
T13423 27360-27369 JJ denotes bacterial
T13422 27358-27359 DT denotes A
T13421 27355-27356 -RRB- denotes ]
T13420 27353-27355 CD denotes 43
T13419 27352-27353 -LRB- denotes [
T13418 27347-27351 NN denotes TNFα
T13417 27342-27346 IN denotes like
T13416 27332-27341 NN denotes mediators
T13415 27315-27331 JJ denotes pro-inflammatory
T13414 27312-27314 IN denotes of
T13413 27301-27311 NN denotes expression
T13412 27298-27300 TO denotes to
T13411 27290-27297 VB denotes leading
T13410 27288-27289 -COMMA- denotes ,
T13409 27281-27288 NN denotes pathway
T13408 27276-27280 NN denotes NFκB
T13407 27272-27275 DT denotes the
T13406 27268-27271 IN denotes via
T13405 27258-27267 NN denotes signaling
T13404 27247-27257 JJ denotes subsequent
T13403 27243-27246 CC denotes and
T13402 27241-27242 CD denotes 4
T13401 27232-27240 NN denotes receptor
T13400 27222-27231 JJ denotes Toll-like
T13399 27214-27221 IN denotes through
T13398 27205-27213 VB denotes mediated
T13397 27198-27204 RB denotes mainly
T13396 27195-27197 VB denotes is
T13395 27191-27194 NN denotes LPS
T13394 27188-27190 IN denotes of
T13393 27176-27187 NN denotes Recognition
T13392 27172-27174 NN denotes GP
T13391 27168-27171 CC denotes and
T13390 27161-27167 NN denotes TSST-1
T13389 27159-27160 -COMMA- denotes ,
T13388 27156-27159 NN denotes LPS
T13387 27148-27155 IN denotes between
T13386 27138-27147 NN denotes signaling
T13385 27134-27137 CC denotes and
T13384 27122-27133 NN denotes recognition
T13383 27119-27121 IN denotes in
T13382 27107-27118 NN denotes differences
T13381 27104-27106 TO denotes to
T13380 27100-27103 JJ denotes due
T13379 27093-27099 RB denotes likely
T13378 27090-27092 VB denotes is
T13377 27084-27089 WDT denotes which
T13376 27082-27083 -COMMA- denotes ,
T13375 27076-27082 NN denotes TSST-1
T13374 27073-27075 CC denotes or
T13373 27069-27072 NN denotes LPS
T13372 27066-27068 IN denotes of
T13371 27061-27065 DT denotes that
T13370 27056-27060 IN denotes than
T13369 27045-27055 JJ denotes restricted
T13368 27040-27044 RB denotes more
T13367 27026-27039 RB denotes substantially
T13366 27022-27025 VB denotes was
T13365 27014-27021 NN denotes profile
T13364 27005-27013 NN denotes cytokine
T13363 26994-27004 JJ denotes GP-induced
T13362 26989-26993 DT denotes This
T13361 26986-26987 -RRB- denotes )
T13360 26981-26986 VB denotes shown
T13359 26977-26980 RB denotes not
T13358 26972-26976 NN denotes data
T13357 26971-26972 -LRB- denotes (
T13356 26968-26970 NN denotes GP
T13355 26965-26967 TO denotes to
T13354 26956-26964 NN denotes response
T13353 26953-26955 IN denotes in
T13352 26946-26952 NN denotes IL-1RA
T13351 26943-26945 IN denotes as
T13350 26938-26942 RB denotes just
T13349 26933-26937 NN denotes IL-8
T13348 26925-26932 VB denotes produce
T13347 26922-26924 TO denotes to
T13346 26917-26921 JJ denotes able
T13345 26912-26916 VB denotes were
T13344 26900-26911 NN denotes neutrophils
T13343 26896-26899 CC denotes and
T13342 26886-26895 NN denotes monocytes
T13341 26881-26885 IN denotes that
T13340 26873-26880 VB denotes confirm
T13339 26870-26872 TO denotes to
T13338 26863-26869 VB denotes seemed
T13337 26851-26862 NN denotes experiments
T13336 26840-26850 JJ denotes cytometric
T13335 26835-26839 NN denotes Flow
T13334 26832-26833 -RRB- denotes ]
T13333 26830-26832 CD denotes 32
T13332 26829-26830 -LRB- denotes [
T13331 26822-26828 NN denotes IL-1RA
T13330 26814-26821 VB denotes produce
T13329 26811-26813 TO denotes to
T13328 26802-26810 VB denotes reported
T13327 26797-26801 VB denotes been
T13326 26792-26796 VB denotes have
T13325 26780-26791 NN denotes neutrophils
T13324 26777-26779 IN denotes as
T13323 26772-26776 RB denotes well
T13322 26769-26771 RB denotes as
T13321 26759-26768 NN denotes monocytes
T13320 26757-26758 -COMMA- denotes ,
T13319 26753-26757 DT denotes both
T13318 26751-26752 -COMMA- denotes ,
T13317 26744-26751 NN denotes sources
T13316 26735-26743 JJ denotes cellular
T13315 26725-26734 VB denotes Regarding
T13314 26722-26723 -RRB- denotes )
T13313 26721-26722 CD denotes 7
T13312 26716-26720 NN denotes Fig.
T13311 26715-26716 -LRB- denotes (
T13310 26708-26714 NN denotes IL-1RA
T13309 26705-26707 IN denotes of
T13308 26695-26704 NN denotes induction
T13307 26691-26694 IN denotes for
T13306 26681-26690 JJ denotes necessary
T13305 26677-26680 CC denotes and
T13304 26671-26676 JJ denotes other
T13303 26666-26670 DT denotes each
T13302 26663-26665 TO denotes to
T13301 26656-26662 VB denotes linked
T13300 26652-26655 VB denotes are
T13299 26646-26651 NN denotes steps
T13298 26640-26645 DT denotes these
T13297 26635-26639 IN denotes that
T13296 26627-26634 VB denotes suggest
T13295 26621-26626 MD denotes might
T13294 26611-26620 NN denotes treatment
T13293 26608-26610 NN denotes GP
T13292 26605-26607 TO denotes to
T13291 26599-26604 RB denotes prior
T13290 26588-26598 NN denotes inhibitors
T13289 26578-26587 JJ denotes selective
T13288 26575-26577 IN denotes by
T13287 26567-26574 VB denotes induced
T13286 26559-26566 NN denotes protein
T13285 26555-26558 CC denotes and
T13284 26550-26554 NN denotes mRNA
T13283 26543-26549 NN denotes IL-1RA
T13282 26540-26542 IN denotes of
T13274 26500-26505 NN denotes sites
T13273 26497-26499 TO denotes to
T13272 26489-26496 NN denotes binding
T13271 26482-26488 NN denotes NFIL-6
T13281 26537-26539 IN denotes as
T13280 26532-26536 RB denotes well
T13279 26529-26531 RB denotes as
T13278 26520-26528 NN denotes promoter
T13277 26513-26519 NN denotes IL-1RA
T13276 26509-26512 DT denotes the
T13275 26506-26508 IN denotes in
T13270 26478-26481 CC denotes and
T13269 26473-26477 NN denotes NFAT
T13268 26471-26472 -COMMA- denotes ,
T13267 26467-26471 NN denotes NFκB
T13266 26464-26466 IN denotes of
T13265 26455-26463 NN denotes decrease
T13264 26442-26454 JJ denotes differential
T13263 26438-26441 DT denotes The
T13262 26428-26436 NN denotes promoter
T13261 26421-26427 NN denotes IL-1RA
T13260 26417-26420 CC denotes and
T13259 26412-26416 NN denotes IL-6
T13258 26410-26411 -COMMA- denotes ,
T13257 26406-26410 NN denotes IFNγ
T13256 26402-26405 DT denotes the
T13255 26394-26401 IN denotes between
T13254 26392-26393 -RRB- denotes )
T13253 26388-26392 NN denotes NFAT
T13252 26387-26388 -LRB- denotes (
T13251 26379-26386 NN denotes factors
T13250 26365-26378 NN denotes transcription
T13249 26355-26364 VB denotes activated
T13248 26351-26354 DT denotes the
T13247 26348-26350 IN denotes of
T13246 26336-26347 NN denotes composition
T13245 26332-26335 DT denotes the
T13779 29643-29646 DT denotes the
T13778 29639-29642 CC denotes and
T13777 29634-29638 NN denotes TNFα
T13776 29630-29633 DT denotes the
T13775 29622-29629 IN denotes between
T13774 29616-29621 NN denotes motif
T13773 29608-29615 NN denotes binding
T13772 29603-29607 NN denotes NFκB
T13771 29593-29602 JJ denotes decameric
T13770 29589-29592 DT denotes the
T13769 29582-29588 IN denotes within
T13768 29580-29581 -RRB- denotes )
T13767 29578-29580 CD denotes 10
T13766 29576-29577 -COMMA- denotes ,
T13765 29575-29576 CD denotes 3
T13764 29573-29574 -COMMA- denotes ,
T13763 29572-29573 CD denotes 2
T13762 29570-29571 -COMMA- denotes ,
T13761 29569-29570 CD denotes 1
T13760 29568-29569 -SHARP- denotes #
T13759 29567-29568 -LRB- denotes (
T13758 29555-29566 NN denotes nucleotides
T13757 29545-29554 VB denotes conserved
T13756 29542-29544 CC denotes or
T13755 29533-29541 NN denotes subunits
T13754 29528-29532 NN denotes NFκB
T13753 29521-29527 DT denotes either
T13752 29518-29520 IN denotes in
T13751 29506-29517 NN denotes differences
T13750 29503-29505 IN denotes by
T13749 29493-29502 VB denotes explained
T13748 29490-29492 VB denotes be
T13747 29484-29489 MD denotes could
T13746 29479-29483 NN denotes data
T13745 29465-29478 JJ denotes contradictory
T13744 29455-29464 RB denotes seemingly
T13743 29449-29454 DT denotes These
T13742 29439-29447 NN denotes promoter
T13741 29432-29438 NN denotes IL-1RA
T13740 29428-29431 DT denotes the
T13739 29425-29427 IN denotes of
T13738 29419-29424 NN denotes sites
T13737 29409-29418 NN denotes consensus
T13736 29404-29408 NN denotes NFκB
T13735 29400-29403 CC denotes and
T13734 29394-29399 NN denotes NFκB3
T13733 29391-29393 TO denotes to
T13732 29377-29390 NN denotes up-regulation
T13731 29374-29376 DT denotes an
T13730 29370-29373 VB denotes was
T13729 29364-29369 EX denotes there
T13728 29362-29363 -COMMA- denotes ,
T13727 29354-29362 NN denotes promoter
T13726 29349-29353 NN denotes TNFα
T13725 29345-29348 DT denotes the
T13724 29342-29344 IN denotes of
T13723 29336-29341 NN denotes sites
T13722 29333-29335 TO denotes to
T13721 29325-29332 VB denotes binding
T13720 29320-29324 NN denotes NFκB
T13719 29305-29319 JJ denotes TSST-1-induced
T13718 29301-29304 DT denotes the
T13717 29297-29300 CC denotes and
T13716 29292-29296 NN denotes LPS-
T13715 29288-29291 DT denotes the
T13714 29285-29287 IN denotes of
T13713 29269-29284 NN denotes down-regulation
T13712 29257-29268 JJ denotes GP-mediated
T13711 29255-29256 DT denotes a
T13710 29246-29254 VB denotes observed
T13709 29243-29245 PRP denotes we
T13708 29237-29242 IN denotes while
T13707 29235-29236 -COMMA- denotes ,
T13706 29233-29235 RB denotes So
T13705 29229-29231 NN denotes GP
T13704 29226-29228 IN denotes by
T13703 29216-29225 VB denotes increased
T13702 29213-29215 VB denotes be
T13701 29210-29212 TO denotes to
T13700 29203-29209 VB denotes seemed
T13699 29198-29202 NN denotes site
T13698 29188-29197 NN denotes consensus
T13697 29183-29187 NN denotes NFκB
T13696 29179-29182 JJ denotes new
T13695 29175-29178 DT denotes the
T13694 29172-29174 TO denotes to
T13693 29164-29171 NN denotes binding
T13692 29149-29163 JJ denotes TSST-1-induced
T13691 29145-29148 DT denotes the
T13690 29141-29144 CC denotes and
T13689 29135-29140 NN denotes NFκB3
T13688 29131-29134 DT denotes the
T13687 29128-29130 TO denotes to
T13686 29120-29127 NN denotes binding
T13685 29108-29119 JJ denotes LPS-induced
T13684 29104-29107 CC denotes and
T13683 29096-29103 NN denotes TSST-1-
T13682 29092-29095 DT denotes the
T13681 29085-29091 RB denotes mostly
T13680 29083-29084 -COMMA- denotes ,
T13679 29075-29083 NN denotes promoter
T13678 29068-29074 NN denotes IL-1RA
T13677 29064-29067 DT denotes the
T13676 29059-29063 IN denotes from
T13675 29053-29058 NN denotes sites
T13674 29048-29052 NN denotes NFκB
T13673 29039-29047 VB denotes examined
T13672 29034-29038 CD denotes four
T13671 29030-29033 DT denotes the
T13670 29027-29029 IN denotes Of
T13669 29024-29025 -RRB- denotes )
T13668 29018-29024 NN denotes detail
T13667 29015-29017 IN denotes in
T13666 29009-29014 VB denotes shown
T13665 29005-29008 RB denotes not
T13664 29000-29004 NN denotes data
T13663 28998-28999 -COLON- denotes ;
T13662 28994-28998 CD denotes 0.01
T13661 28992-28993 SYM denotes <
T13660 28990-28991 NN denotes p
T13659 28988-28989 -COLON- denotes ;
T13658 28983-28988 CD denotes -0.88
T13657 28981-28982 SYM denotes =
T13656 28979-28980 NN denotes r
T13655 28978-28979 -LRB- denotes (
T13654 28967-28977 NN denotes production
T13653 28960-28966 NN denotes IL-1RA
T13652 28945-28959 JJ denotes TSST-1-induced
T13244 26329-26331 CC denotes or
T13243 26323-26328 NN denotes motif
T13242 26315-26322 VB denotes binding
T13241 26311-26314 DT denotes the
T13240 26308-26310 IN denotes in
T13239 26296-26307 NN denotes differences
T13238 26293-26295 TO denotes to
T13237 26289-26292 JJ denotes due
T13236 26286-26288 VB denotes be
T13235 26280-26285 MD denotes might
T13234 26274-26279 WDT denotes which
T13233 26272-26273 -COMMA- denotes ,
T13232 26265-26272 NN denotes binding
T13231 26261-26264 NN denotes DNA
T13230 26254-26260 NN denotes NFIL-6
T13229 26250-26253 CC denotes and
T13228 26241-26249 NN denotes NFATP2/3
T13227 26238-26240 IN denotes of
T13226 26228-26237 NN denotes induction
T13225 26224-26227 IN denotes via
T13224 26214-26223 RB denotes primarily
T13223 26207-26213 NN denotes IL-1RA
T13222 26204-26206 IN denotes of
T13221 26193-26203 NN denotes production
T13220 26190-26192 TO denotes to
T13219 26184-26189 VB denotes leads
T13007 25040-25047 NNP denotes Schulte
T13006 25037-25039 IN denotes by
T13005 25029-25036 NN denotes Results
T13004 25026-25027 -RRB- denotes )
T13003 25025-25026 CD denotes 2
T13002 25023-25024 -COMMA- denotes ,
T13001 25021-25023 NN denotes 1A
T13000 25015-25020 NNP denotes Figs.
T12999 25014-25015 -LRB- denotes (
T12998 25005-25013 NN denotes promoter
T12997 25000-25004 NN denotes IL-8
T12996 24996-24999 DT denotes the
T12995 24993-24995 IN denotes of
T12994 24988-24992 NN denotes site
T12993 24978-24987 NN denotes consensus
T12992 24975-24977 NN denotes κB
T12991 24973-24974 DT denotes a
T12990 24970-24972 TO denotes to
T12989 24966-24969 NN denotes p50
T12988 24963-24965 IN denotes of
T12987 24956-24962 NN denotes extent
T12986 24949-24955 JJ denotes lesser
T12985 24947-24948 DT denotes a
T12984 24944-24946 TO denotes to
T12983 24940-24943 CC denotes and
T12982 24936-24939 NN denotes p65
T12981 24931-24935 NN denotes NFκB
T12980 24928-24930 IN denotes of
T12979 24920-24927 NN denotes binding
T12978 24908-24919 JJ denotes predominant
T12977 24896-24907 JJ denotes GP-mediated
T12976 24894-24895 DT denotes a
T12975 24881-24893 VB denotes demonstrated
T12974 24873-24880 NN denotes results
T12973 24858-24872 NN denotes immunoblotting
T12972 24854-24857 CC denotes and
T12971 24838-24853 NN denotes EMSA/supershift
T12970 24834-24837 PRP-DOLLAR- denotes our
T12969 24832-24833 -COMMA- denotes ,
T12968 24824-24832 NN denotes addition
T12967 24821-24823 IN denotes In
T12966 24818-24819 -RRB- denotes ]
T12965 24816-24818 CD denotes 17
T12964 24815-24816 -LRB- denotes [
T12963 24804-24814 NN denotes production
T12962 24797-24803 NN denotes IL-1RA
T12961 24793-24796 CC denotes and
T12960 24791-24792 -RRB- denotes ]
T12959 24784-24791 CD denotes 6,16,19
T12958 24783-24784 -LRB- denotes [
T12957 24778-24782 NN denotes IL-8
T12956 24754-24777 JJ denotes β-1→3-D-glucan-mediated
T12955 24752-24753 DT denotes a
T12954 24741-24751 VB denotes describing
T12953 24733-24740 NN denotes reports
T12952 24729-24732 JJ denotes few
T12951 24725-24728 DT denotes the
T12950 24720-24724 IN denotes with
T12949 24709-24719 NN denotes aggreement
T12948 24706-24708 IN denotes in
T12947 24702-24705 VB denotes are
T12946 24697-24701 NN denotes data
T12945 24693-24696 PRP-DOLLAR- denotes our
T12944 24691-24692 -COMMA- denotes ,
T12943 24686-24691 RB denotes Hence
T12942 24683-24684 -RRB- denotes )
T12941 24681-24683 NN denotes 3B
T12940 24676-24680 NN denotes Fig.
T12939 24675-24676 -LRB- denotes (
T12938 24668-24674 NN denotes IL-1RA
T12937 24664-24667 CC denotes and
T12936 24659-24663 NN denotes IL-8
T12935 24652-24658 RB denotes namely
T12934 24650-24651 -COMMA- denotes ,
T12933 24642-24650 NN denotes response
T12932 24633-24641 NN denotes cytokine
T12931 24625-24632 JJ denotes limited
T12930 24620-24624 RB denotes very
T12929 24618-24619 DT denotes a
T12928 24613-24617 IN denotes into
T12927 24608-24612 RB denotes only
T12926 24596-24607 VB denotes transformed
T12925 24588-24595 NN denotes binding
T12924 24581-24587 NN denotes factor
T12923 24567-24580 NN denotes transcription
T12922 24556-24566 JJ denotes GP-induced
T12921 24552-24555 DT denotes the
T12920 24550-24551 -COMMA- denotes ,
T12919 24537-24550 RB denotes Interestingly
T12918 24534-24535 -RRB- denotes ]
T12917 24532-24534 CD denotes 38
T12916 24531-24532 -LRB- denotes [
T12915 24522-24530 NN denotes splicing
T12914 24510-24521 JJ denotes alternative
T12913 24505-24509 IN denotes from
T12912 24497-24504 VB denotes derived
T12911 24488-24496 RB denotes probably
T12910 24486-24487 -COMMA- denotes ,
T12909 24478-24486 NN denotes isoforms
T12908 24473-24477 NN denotes NFAT
T12907 24463-24472 JJ denotes different
T12906 24455-24462 JJ denotes several
T12905 24452-24454 IN denotes of
T12904 24441-24451 NN denotes activation
T12903 24438-24440 VB denotes is
T12902 24432-24437 EX denotes there
T12901 24427-24431 IN denotes that
T12900 24417-24426 VB denotes speculate
T12899 24411-24416 MD denotes could
T12898 24407-24410 PRP denotes one
T12897 24405-24406 -COMMA- denotes ,
T12896 24404-24405 -RRB- denotes )
T12895 24402-24404 NN denotes 1A
T12894 24397-24401 NN denotes Fig.
T12893 24396-24397 -LRB- denotes (
T12892 24388-24395 NN denotes binding
T12891 24383-24387 NN denotes NFAT
T12890 24379-24382 IN denotes for
T12889 24370-24378 VB denotes observed
T12888 24363-24369 NN denotes shifts
T12887 24358-24362 NN denotes band
T12886 24349-24357 JJ denotes multiple
T12885 24345-24348 DT denotes the
T12884 24342-24344 IN denotes of
T12883 24334-24341 IN denotes Because
T12882 24323-24332 NN denotes promoters
T12881 24314-24322 NN denotes cytokine
T12880 24311-24313 TO denotes to
T12879 24301-24310 NN denotes NFAT-mers
T12878 24297-24300 CC denotes and
T12877 24289-24296 NN denotes NFIL-6-
T12876 24287-24288 -COMMA- denotes ,
T12875 24282-24287 NN denotes NFκB-
T12874 24279-24281 IN denotes of
T12873 24271-24278 NN denotes binding
T12872 24263-24270 VB denotes induced
T12871 24247-24262 NN denotes β-1→3-D-glucans
T12870 24245-24246 -COMMA- denotes ,
T12869 24238-24245 NN denotes stimuli
T12868 24232-24237 JJ denotes other
T12867 24229-24231 IN denotes of
T12866 24221-24228 NN denotes absence
T12865 24217-24220 DT denotes the
T12864 24214-24216 IN denotes in
T12863 24212-24213 -COMMA- denotes ,
T12862 24208-24212 IN denotes that
T12861 24197-24207 VB denotes indicating
T12860 24195-24196 -RRB- denotes ]
T12859 24190-24195 CD denotes 13-16
T12858 24189-24190 -LRB- denotes [
T12857 24181-24188 NN denotes results
T12856 24172-24180 JJ denotes previous
T12855 24163-24171 VB denotes extended
T12854 24159-24162 CC denotes and
T12853 24149-24158 VB denotes confirmed
T12852 24146-24148 PRP denotes We
T12851 24142-24144 NN denotes GP
T12850 24139-24141 IN denotes by
T12849 24129-24138 NN denotes phenotype
T12848 24111-24128 JJ denotes anti-inflammatory
T12847 24108-24110 DT denotes an
T12846 24105-24107 TO denotes to
T12845 24096-24104 VB denotes switched
T12844 24093-24095 VB denotes is
T12843 24082-24092 NN denotes leukocytes
T12842 24076-24081 JJ denotes human
T12841 24073-24075 IN denotes of
T12840 24062-24072 NN denotes expression
T12839 24053-24061 NN denotes cytokine
T12838 24049-24052 CC denotes and
T12837 24041-24048 NN denotes binding
T12836 24034-24040 NN denotes factor
T12835 24020-24033 NN denotes transcription
T12834 24003-24019 JJ denotes pro-inflammatory
T12833 23993-24002 NN denotes signaling
T12832 23989-23992 CC denotes and
T12831 23977-23988 NN denotes recognition
T12830 23974-23976 IN denotes of
T12829 23963-23973 JJ denotes downstream
T12828 23958-23962 IN denotes that
T12827 23949-23957 NN denotes evidence
T12826 23943-23948 JJ denotes novel
T12825 23934-23942 VB denotes provides
T12824 23928-23933 NN denotes study
T12823 23924-23927 PRP-DOLLAR- denotes Our
T12822 23921-23922 -RRB- denotes ]
T12821 23916-23921 CD denotes 22,37
T12820 23915-23916 -LRB- denotes [
T12819 23900-23914 NN denotes PI3K-signaling
T12818 23897-23899 TO denotes to
T13435 27453-27456 DT denotes the
T12817 23891-23896 NN denotes NFκB-
T12816 23886-23890 IN denotes from
T12815 23880-23885 NN denotes shift
T12814 23874-23879 JJ denotes rapid
T12813 23872-23873 DT denotes a
T12812 23868-23871 IN denotes via
T12811 23866-23867 -COMMA- denotes ,
T12810 23862-23866 NN denotes part
T12809 23859-23861 IN denotes in
T12808 23857-23858 -COMMA- denotes ,
T12807 23847-23857 NN denotes mechanisms
T12806 23836-23846 JJ denotes protective
T12805 23832-23835 PRP-DOLLAR- denotes its
T12804 23823-23831 VB denotes mediates
T12803 23820-23822 NN denotes GP
T12802 23815-23819 IN denotes like
T12801 23800-23814 NN denotes β-1→3-D-glucan
T12800 23798-23799 DT denotes a
T12799 23793-23797 IN denotes that
T12798 23785-23792 VB denotes suggest
T12797 23778-23784 NN denotes injury
T12796 23767-23777 JJ denotes myocardial
T12795 23763-23766 CC denotes and
T12794 23756-23762 NN denotes sepsis
T12793 23753-23755 IN denotes of
T12792 23746-23752 NN denotes models
T13197 26087-26091 NN denotes site
T13196 26079-26086 NN denotes NFκB2/3
T13195 26071-26078 DT denotes another
T13194 26069-26070 -COMMA- denotes ,
T13193 26068-26069 -RRB- denotes )
T13192 26064-26068 CD denotes -280
T13191 26060-26063 CC denotes and
T13190 26055-26059 CD denotes -266
T13189 26054-26055 -LRB- denotes (
T13188 26049-26053 NN denotes site
T13187 26039-26048 NN denotes consensus
T13186 26034-26038 NN denotes NFκB
T13185 26031-26033 DT denotes an
T13184 26029-26030 -COMMA- denotes ,
T13183 26028-26029 -RRB- denotes )
T13182 26024-26028 CD denotes -130
T13181 26020-26023 CC denotes and
T13180 26015-26019 CD denotes -100
T13179 26007-26014 IN denotes between
T13178 26006-26007 -LRB- denotes (
T13177 26001-26005 NN denotes site
T13176 25995-26000 NN denotes NFκB3
T13175 25992-25994 DT denotes an
T13174 25990-25991 -COLON- denotes :
T13173 25989-25990 -RRB- denotes )
T13172 25988-25989 CD denotes 8
T13171 25983-25987 NN denotes Fig.
T13170 25982-25983 -LRB- denotes (
T13169 25976-25981 NN denotes sites
T13168 25968-25975 VB denotes binding
T13167 25964-25967 JJ denotes new
T13166 25959-25963 CD denotes four
T13165 25948-25958 VB denotes discovered
T13164 25945-25947 PRP denotes we
T13163 25943-25944 -COMMA- denotes ,
T13162 25942-25943 -RRB- denotes ]
T13161 25940-25942 CD denotes 34
T13160 25939-25940 -LRB- denotes [
T13159 25930-25938 NN denotes promoter
T13158 25923-25929 NN denotes IL-1RA
T13157 25919-25922 DT denotes the
T13156 25909-25918 VB denotes Analysing
T13155 25905-25907 NN denotes GP
T13154 25902-25904 IN denotes of
T13153 25892-25901 NN denotes potential
T13152 25874-25891 JJ denotes anti-inflammatory
T13151 25864-25873 JJ denotes immediate
T13150 25861-25863 DT denotes an
T13149 25850-25860 VB denotes suggesting
T13148 25848-25849 -COMMA- denotes ,
T13147 25842-25848 NN denotes IL-1RA
T13146 25834-25841 VB denotes induced
T13145 25825-25833 RB denotes strongly
T13144 25822-25824 PRP denotes it
T13143 25818-25821 CC denotes but
T13142 25816-25817 -COMMA- denotes ,
T13141 25811-25816 NN denotes IL-1β
T13140 25804-25810 VB denotes induce
T13139 25800-25803 RB denotes not
T13138 25796-25799 VB denotes did
T13137 25793-25795 NN denotes GP
T13136 25788-25792 IN denotes that
T13135 25782-25787 VB denotes found
T13134 25779-25781 PRP denotes we
T13133 25777-25778 -COMMA- denotes ,
T13132 25771-25777 NN denotes TSST-1
T13131 25768-25770 CC denotes or
T13130 25764-25767 NN denotes LPS
T13129 25757-25763 IN denotes Unlike
T13128 25754-25755 -RRB- denotes ]
T13127 25749-25754 CD denotes 41,42
T13126 25748-25749 -LRB- denotes [
T13125 25742-25747 NN denotes motif
T13124 25739-25741 NN denotes κB
T13123 25729-25738 JJ denotes decameric
T13122 25725-25728 DT denotes the
T13121 25722-25724 IN denotes of
T13120 25713-25721 NN denotes sequence
T13119 25704-25712 JJ denotes specific
T13118 25700-25703 DT denotes the
T13117 25696-25699 CC denotes and
T13116 25687-25695 NN denotes subunits
T13115 25683-25686 DT denotes the
T13114 25680-25682 IN denotes of
T13113 25667-25679 NN denotes associations
T13112 25653-25666 JJ denotes combinatorial
T13111 25645-25652 IN denotes through
T13110 25637-25644 NN denotes binding
T13109 25632-25636 NN denotes NFκB
T13108 25621-25631 VB denotes regulating
T13107 25618-25620 IN denotes of
T13106 25613-25617 NN denotes idea
T13105 25609-25612 DT denotes the
T13104 25598-25608 VB denotes supporting
T13103 25596-25597 -COMMA- denotes ,
T13102 25595-25596 -RRB- denotes ]
T13101 25590-25595 CD denotes 27,40
T13100 25589-25590 -LRB- denotes [
T13099 25583-25588 NN denotes IL-1β
T13098 25579-25582 CC denotes and
T13097 25574-25578 NN denotes TNFα
T13096 25570-25573 IN denotes for
T13095 25560-25569 VB denotes described
T13094 25555-25559 NN denotes site
T13093 25550-25554 NN denotes half
T13092 25547-25549 NN denotes κB
T13091 25543-25546 DT denotes the
T13090 25538-25542 IN denotes from
T13089 25530-25537 VB denotes differs
T13088 25525-25529 RB denotes thus
T13087 25521-25524 CC denotes and
T13086 25516-25520 NN denotes site
T13085 25511-25515 NN denotes half
T13084 25503-25510 NN denotes binding
T13083 25499-25502 NN denotes p65
T13082 25484-25498 RB denotes preferentially
T13081 25482-25483 DT denotes a
T13080 25473-25481 VB denotes exhibits
T13079 25468-25472 NN denotes site
T13078 25458-25467 NN denotes consensus
T13077 25451-25457 NN denotes IL-8κB
T13076 25447-25450 DT denotes The
T13075 25437-25445 JJ denotes possible
T13074 25432-25436 RB denotes also
T13073 25426-25431 VB denotes seems
T13072 25424-25425 -RRB- denotes ]
T13071 25422-25424 CD denotes 38
T13070 25421-25422 -LRB- denotes [
T13069 25416-25420 NN denotes site
T13068 25409-25415 NN denotes IL-8κB
T13067 25405-25408 DT denotes the
T13066 25402-25404 TO denotes to
T13065 25394-25401 VB denotes binding
T13064 25388-25393 NN denotes dimer
T13063 25381-25387 NN denotes NFATc2
T13062 25378-25380 CC denotes or
T13061 25376-25377 -RRB- denotes ]
T13060 25371-25376 CD denotes 13,39
T13059 25370-25371 -LRB- denotes [
T13058 25363-25369 NN denotes NFIL-6
T13057 25359-25362 CC denotes and
T13056 25355-25358 NN denotes p65
T13055 25350-25354 NN denotes NFκB
T13054 25335-25349 VB denotes transactivated
T13053 25327-25334 IN denotes between
T13052 25315-25326 NN denotes cooperation
T13051 25313-25314 DT denotes a
T13050 25308-25312 IN denotes upon
T13049 25302-25307 VB denotes based
T13048 25288-25301 NN denotes transcription
T13047 25283-25287 NN denotes IL-8
T13046 25271-25282 JJ denotes GP-mediated
T13045 25269-25270 DT denotes A
T13044 25254-25267 NN denotes transcription
T13043 25249-25253 NN denotes IL-8
T13042 25237-25248 JJ denotes GP-mediated
T13041 25233-25236 DT denotes the
T13040 25229-25232 IN denotes for
T13039 25224-25228 NN denotes case
T13038 25220-25223 DT denotes the
T13037 25217-25219 VB denotes be
T13036 25211-25216 MD denotes might
T13035 25205-25210 WDT denotes which
T13034 25203-25204 -COMMA- denotes ,
T13033 25191-25203 NN denotes heterodimers
T13032 25184-25190 NN denotes p65/50
T13031 25180-25183 IN denotes via
T13030 25175-25179 IN denotes than
T13010 25063-25064 -LRB- denotes [
T13009 25052-25062 NN denotes colleagues
T13008 25048-25051 CC denotes and
T13029 25168-25174 RB denotes rather
T13028 25166-25167 -COMMA- denotes ,
T13027 25157-25166 NN denotes homodimer
T13026 25150-25156 NN denotes p65/65
T13025 25145-25149 NN denotes NFκB
T13024 25142-25144 DT denotes an
T13023 25138-25141 IN denotes via
T13022 25127-25137 NN denotes activation
T13021 25124-25126 IN denotes on
T13020 25114-25123 VB denotes depending
T13019 25100-25113 NN denotes transcription
T13018 25095-25099 NN denotes IL-8
T13017 25092-25094 IN denotes of
T13016 25082-25091 NN denotes induction
T13015 25079-25081 DT denotes an
T13014 25076-25078 TO denotes to
T13013 25068-25075 VB denotes pointed
T13012 25066-25067 -RRB- denotes ]
T13011 25064-25066 CD denotes 28
T13218 26181-26183 NN denotes GP
T13217 26176-26180 IN denotes that
T13216 26166-26175 VB denotes indicated
T13215 26161-26165 NN denotes data
T13214 26157-26160 PRP-DOLLAR- denotes Our
T13213 26154-26155 -RRB- denotes )
T13212 26150-26154 CD denotes -490
T13211 26146-26149 CC denotes and
T13210 26141-26145 CD denotes -471
T13209 26140-26141 -LRB- denotes (
T13208 26135-26139 NN denotes site
T13207 26126-26134 NN denotes NFATP2/3
T13206 26119-26125 JJ denotes distal
T13205 26114-26118 RB denotes more
T13204 26112-26113 DT denotes a
T13203 26108-26111 CC denotes and
T13202 26106-26107 -RRB- denotes )
T13201 26102-26106 CD denotes -302
T13200 26098-26101 CC denotes and
T13199 26093-26097 CD denotes -288
T13198 26092-26093 -LRB- denotes (
T12791 23739-23745 NN denotes Animal
T10779 22797-22804 NN denotes release
T10778 22790-22796 NN denotes IL-1RA
T10777 22780-22789 VB denotes decreased
T10776 22778-22779 DT denotes a
T10775 22775-22777 TO denotes to
T10774 22771-22774 VB denotes led
T10773 22764-22770 RB denotes mainly
T10772 22760-22763 NN denotes CHX
T10771 22756-22759 CC denotes and
T10770 22752-22755 NN denotes CyA
T10769 22744-22751 IN denotes whereas
T10768 22742-22743 -COMMA- denotes ,
T10767 22729-22742 NN denotes transcription
T10766 22725-22728 DT denotes the
T10765 22721-22724 CC denotes and
T10764 22712-22720 NN denotes activity
T10763 22704-22711 NN denotes binding
T10762 22700-22703 DT denotes the
T10761 22697-22699 IN denotes at
T10760 22686-22696 JJ denotes pronounced
T10759 22681-22685 RB denotes more
T10758 22677-22680 VB denotes was
T10757 22672-22676 NN denotes CAPE
T10756 22669-22671 IN denotes by
T10755 22658-22668 NN denotes inhibition
T10754 22653-22657 NN denotes NFκB
T10753 22651-22652 -COMMA- denotes ,
T10752 22641-22651 RB denotes Altogether
T10751 22638-22639 -RRB- denotes )
T10750 22637-22638 CD denotes 3
T10749 22635-22636 SYM denotes =
T10748 22633-22634 NN denotes n
T10747 22632-22633 -LRB- denotes (
T10746 22629-22631 NN denotes 7C
T10745 22624-22628 NNP denotes Fig.
T10744 22621-22623 IN denotes in
T10743 22615-22620 VB denotes shown
T10742 22611-22614 VB denotes are
T10741 22608-22610 NN denotes GP
T10740 22605-22607 IN denotes of
T10739 22603-22604 NN denotes h
T10738 22600-22602 CD denotes 24
T10737 22594-22599 IN denotes after
T10736 22587-22593 NN denotes levels
T10735 22579-22586 NN denotes protein
T10734 22572-22578 NN denotes IL-1RA
T10733 22558-22571 VB denotes corresponding
T10732 22556-22557 -COMMA- denotes ,
T10731 22548-22556 NN denotes addition
T10730 22545-22547 IN denotes In
T10729 22542-22543 -RRB- denotes )
T10728 22541-22542 CD denotes 4
T10727 22539-22540 SYM denotes =
T10726 22537-22538 NN denotes n
T10725 22536-22537 -LRB- denotes (
T10724 22533-22535 NN denotes 7B
T10723 22528-22532 NNP denotes Fig.
T10722 22525-22527 IN denotes in
T10721 22515-22524 VB denotes displayed
T10720 22512-22514 VB denotes is
T10719 22508-22511 NN denotes CHX
T10718 22504-22507 CC denotes and
T10717 22500-22503 NN denotes CyA
T10716 22498-22499 -COMMA- denotes ,
T10715 22494-22498 NN denotes CAPE
T10714 22489-22493 IN denotes with
T10713 22478-22488 NN denotes inhibition
T10712 22472-22477 IN denotes after
T10711 22467-22471 NN denotes mRNA
T10710 22460-22466 NN denotes IL-1RA
T10709 22457-22459 IN denotes in
T10708 22448-22456 NN denotes decrease
T10707 22446-22447 DT denotes a
T10706 22432-22445 VB denotes demonstrating
T10705 22428-22431 NN denotes gel
T10704 22413-22427 JJ denotes representative
T10703 22411-22412 DT denotes A
T10702 22407-22409 NN denotes GP
T10701 22404-22406 IN denotes of
T10700 22402-22403 NN denotes h
T10699 22399-22401 CD denotes 18
T10698 22395-22398 CC denotes and
T10697 22384-22394 NN denotes inhibition
T10696 22382-22383 NN denotes h
T10695 22380-22381 CD denotes 1
T10694 22370-22379 VB denotes following
T10693 22361-22369 VB denotes examined
T10692 22357-22360 VB denotes was
T10691 22352-22356 NN denotes mRNA
T10690 22350-22351 -COMMA- denotes ,
T10689 22349-22350 NN denotes h
T10688 22346-22348 CD denotes 24
T10687 22343-22345 IN denotes at
T10686 22337-22342 VB denotes found
T10685 22333-22336 VB denotes was
T10684 22326-22332 NN denotes amount
T10683 22319-22325 NN denotes IL-1RA
T10682 22311-22318 JJ denotes highest
T10681 22307-22310 DT denotes the
T10680 22299-22306 IN denotes Because
T10679 22296-22297 -RRB- denotes )
T10678 22291-22296 VB denotes shown
T10677 22287-22290 RB denotes not
T10676 22282-22286 NN denotes data
T10675 22281-22282 -LRB- denotes (
T10674 22273-22280 JJ denotes similar
T10673 22268-22272 VB denotes were
T10672 22262-22267 NN denotes sites
T10671 22254-22261 NN denotes binding
T10670 22247-22253 NN denotes NFIL-6
T10669 22243-22246 CC denotes and
T10668 22238-22242 NN denotes NFκB
T10667 22234-22237 DT denotes the
T10666 22230-22233 IN denotes for
T10665 22222-22229 NN denotes results
T10664 22218-22221 DT denotes The
T10663 22215-22216 -RRB- denotes )
T10662 22211-22215 NN denotes side
T10661 22205-22210 JJ denotes right
T10660 22203-22204 -COMMA- denotes ,
T10659 22201-22203 NNP denotes 7A
T10658 22196-22200 NNP denotes Fig.
T10657 22194-22195 -COMMA- denotes ,
T10656 22193-22194 CD denotes 4
T10655 22191-22192 SYM denotes =
T10654 22189-22190 NN denotes n
T10653 22188-22189 -LRB- denotes (
T10652 22177-22187 VB denotes summarized
T10651 22165-22176 RB denotes graphically
T10650 22161-22164 CC denotes and
T10649 22159-22160 -RRB- denotes )
T10648 22155-22159 NN denotes side
T10647 22150-22154 JJ denotes left
T10646 22148-22149 -COMMA- denotes ,
T10645 22146-22148 NNP denotes 7A
T10644 22141-22145 NNP denotes Fig.
T10643 22140-22141 -LRB- denotes (
T10642 22126-22139 NN denotes autoradiogram
T10641 22123-22125 DT denotes an
T10640 22120-22122 IN denotes in
T10639 22114-22119 VB denotes shown
T10638 22102-22113 RB denotes exemplarily
T10637 22099-22101 VB denotes is
T10636 22091-22098 NN denotes binding
T10635 22082-22090 NN denotes NFATP2/3
T10634 22079-22081 IN denotes in
T10633 22069-22078 NN denotes reduction
T10632 22066-22068 IN denotes of
T10631 22059-22065 NN denotes extent
T10630 22055-22058 DT denotes The
T10629 22052-22053 -RRB- denotes )
T10628 22051-22052 CD denotes 7
T10627 22046-22050 NN denotes Fig.
T10626 22045-22046 -LRB- denotes (
T10625 22038-22044 NN denotes levels
T10624 22030-22037 NN denotes protein
T10623 22023-22029 NN denotes IL-1RA
T10622 22019-22022 CC denotes and
T10621 22014-22018 NN denotes mRNA
T10620 22007-22013 NN denotes IL-1RA
T10619 22004-22006 IN denotes of
T10618 21994-22003 NN denotes reduction
T10617 21992-21993 DT denotes a
T10616 21988-21991 CC denotes and
T10615 21986-21987 -COMMA- denotes ,
T10614 21981-21986 NN denotes sites
T10613 21974-21980 NN denotes IL-1RA
T10612 21970-21973 DT denotes the
T10611 21967-21969 TO denotes to
T10610 21959-21966 NN denotes factors
T10609 21945-21958 NN denotes transcription
T10608 21941-21944 DT denotes the
T10607 21938-21940 IN denotes of
T10606 21929-21937 NN denotes activity
T10605 21921-21928 NN denotes binding
T10604 21906-21920 JJ denotes down-regulated
T10603 21904-21905 DT denotes a
T10602 21901-21903 TO denotes to
T10601 21893-21900 VB denotes leading
T10600 21891-21892 -COMMA- denotes ,
T10599 21889-21891 NN denotes GP
T10598 21886-21888 IN denotes by
T10597 21876-21885 VB denotes overruled
T10596 21873-21875 VB denotes be
T10595 21869-21872 RB denotes not
T10594 21863-21868 MD denotes could
T10593 21861-21862 -RRB- denotes ]
T10592 21859-21861 CD denotes 36
T10591 21858-21859 -LRB- denotes [
T10590 21854-21857 NN denotes CHX
T10589 21850-21853 IN denotes via
T10588 21843-21849 NN denotes NFIL-6
T10587 21839-21842 CC denotes and
T10586 21835-21838 NN denotes CyA
T10585 21831-21834 IN denotes via
T10584 21826-21830 NN denotes NFAT
T10583 21824-21825 -COMMA- denotes ,
T10582 21821-21824 NN denotes CyA
T10581 21817-21820 CC denotes and
T10580 21815-21816 -RRB- denotes ]
T10579 21813-21815 CD denotes 35
T10578 21812-21813 -LRB- denotes [
T10577 21807-21811 NN denotes CAPE
T10576 21803-21806 IN denotes via
T10575 21798-21802 NN denotes NFκB
T10574 21795-21797 IN denotes of
T10573 21784-21794 NN denotes inhibition
T10572 21781-21783 DT denotes an
T10571 21779-21780 -COMMA- denotes ,
T10570 21771-21779 VB denotes expected
T10569 21768-21770 IN denotes As
T10568 21764-21766 NN denotes GP
T10567 21761-21763 IN denotes by
T10566 21754-21760 NN denotes IL-1RA
T10565 21751-21753 IN denotes of
T10564 21741-21750 NN denotes induction
T10563 21737-21740 DT denotes the
T10562 21733-21736 IN denotes for
T10561 21724-21732 JJ denotes relevant
T10560 21720-21723 VB denotes are
T10559 21711-21719 NN denotes promoter
T10558 21704-21710 NN denotes IL-1RA
T10557 21700-21703 DT denotes the
T10556 21693-21699 IN denotes within
T10555 21687-21692 NN denotes sites
T10554 21680-21686 NN denotes factor
T10553 21666-21679 NN denotes transcription
T10552 21662-21665 DT denotes the
T10551 21657-21661 IN denotes that
T10550 21645-21656 VB denotes demonstrate
T10549 21642-21644 TO denotes to
T10548 21637-21641 VB denotes used
T10547 21632-21636 VB denotes were
T10546 21621-21631 NN denotes inhibitors
T10545 21605-21620 JJ denotes Pharmacological
T10544 21598-21604 NN denotes levels
T10543 21591-21597 NN denotes IL-1RA
T10542 21583-21590 VB denotes reduced
T10541 21580-21582 TO denotes to
T10540 21576-21579 VB denotes led
T10539 21568-21575 NN denotes factors
T10538 21554-21567 NN denotes transcription
T10537 21551-21553 IN denotes of
T10536 21540-21550 NN denotes Inhibition
T9864 20798-20799 -RRB- denotes )
T9863 20794-20798 CD denotes 0.07
T9862 20792-20793 JJ denotes <
T9861 20790-20791 NN denotes p
T9860 20788-20789 -COLON- denotes ;
T9859 20787-20788 CD denotes 4
T9858 20785-20786 SYM denotes =
T9857 20783-20784 NN denotes n
T9856 20781-20782 -COMMA- denotes ,
T9855 20775-20781 NN denotes detail
T9854 20772-20774 IN denotes in
T9853 20766-20771 VB denotes shown
T9852 20762-20765 RB denotes not
T9851 20757-20761 NN denotes data
T9850 20756-20757 -LRB- denotes (
T9849 20750-20755 NN denotes calc.
T9848 20740-20749 NN denotes GP/TSST-1
T9847 20737-20739 CC denotes or
T9846 20730-20736 NN denotes TSST-1
T9845 20727-20729 TO denotes to
T9844 20718-20726 VB denotes compared
T9843 20713-20717 WRB denotes when
T9842 20706-20712 NN denotes TSST-1
T9841 20704-20705 SYM denotes +
T9840 20701-20703 NN denotes GP
T9839 20691-20700 VB denotes following
T9838 20685-20690 NN denotes cells
T9837 20680-20684 NN denotes EL-4
T9836 20673-20679 JJ denotes murine
T9835 20668-20672 IN denotes from
T9834 20663-20667 NN denotes IL-2
T9833 20660-20662 IN denotes of
T9832 20652-20659 NN denotes release
T9831 20642-20651 JJ denotes dependent
T9830 20637-20641 NN denotes IL-1
T9829 20633-20636 DT denotes the
T9828 20630-20632 IN denotes of
T9827 20621-20629 NN denotes decrease
T9826 20619-20620 DT denotes a
T9825 20616-20618 IN denotes by
T9824 20606-20615 VB denotes suggested
T9823 20602-20605 VB denotes was
T9822 20595-20601 NN denotes result
T9821 20590-20594 DT denotes this
T9820 20587-20589 IN denotes of
T9819 20577-20586 NN denotes relevance
T9818 20566-20576 JJ denotes biological
T9817 20564-20565 DT denotes A
T9816 20561-20562 -RRB- denotes )
T9815 20560-20561 CD denotes 6
T9814 20555-20559 NNP denotes Fig.
T9813 20553-20554 -COLON- denotes ;
T9812 20549-20553 CD denotes 0.05
T9811 20547-20548 SYM denotes <
T9810 20545-20546 NN denotes p
T9809 20540-20544 CC denotes both
T9808 20538-20539 -COLON- denotes ;
T9807 20537-20538 CD denotes 3
T9806 20535-20536 SYM denotes =
T9805 20533-20534 NN denotes n
T9804 20532-20533 -LRB- denotes (
T9803 20526-20531 NN denotes IL-1β
T9802 20523-20525 IN denotes of
T9801 20518-20522 IN denotes than
T9800 20511-20517 NN denotes IL-1RA
T9799 20508-20510 IN denotes of
T9798 20497-20507 NN denotes production
T9797 20490-20496 JJ denotes higher
T9796 20488-20489 DT denotes a
T9795 20483-20487 FW denotes i.e.
T9794 20481-20482 -COMMA- denotes ,
T9793 20471-20481 NN denotes incubation
T9792 20468-20470 IN denotes of
T9791 20466-20467 NN denotes h
T9790 20463-20465 CD denotes 24
T9789 20459-20462 CC denotes and
T9788 20457-20458 NN denotes h
T9787 20454-20456 CD denotes 18
T9786 20451-20453 IN denotes at
T9785 20445-20450 NN denotes ratio
T9784 20437-20444 VB denotes reduced
T9783 20432-20436 JJ denotes fold
T9782 20425-20431 CD denotes 10–100
T9781 20419-20424 IN denotes about
T9780 20416-20418 DT denotes an
T9779 20413-20415 IN denotes by
T9778 20400-20412 VB denotes demonstrated
T9777 20397-20399 IN denotes as
T9776 20395-20396 -COMMA- denotes ,
T9775 20393-20395 NN denotes GP
T9774 20390-20392 IN denotes of
T9773 20383-20389 NN denotes action
T9772 20365-20382 JJ denotes anti-inflammatory
T9771 20354-20364 JJ denotes pronounced
T9770 20352-20353 DT denotes a
T9769 20343-20351 VB denotes observed
T9768 20340-20342 PRP denotes we
T9767 20338-20339 -COMMA- denotes ,
T9766 20332-20338 NN denotes TSST-1
T9765 20330-20331 SYM denotes +
T9764 20327-20329 NN denotes GP
T9763 20323-20326 FW denotes vs.
T9762 20317-20322 NN denotes calc.
T9761 20307-20316 NN denotes GP/TSST-1
T9760 20304-20306 IN denotes of
T9759 20298-20303 NN denotes value
T9758 20286-20297 JJ denotes theoretical
T9757 20282-20285 DT denotes the
T9756 20279-20281 CC denotes or
T9755 20272-20278 NN denotes TSST-1
T9754 20269-20271 TO denotes to
T9753 20261-20268 NN denotes respect
T9752 20256-20260 IN denotes With
T9751 20253-20254 NN denotes h
T9750 20251-20252 CD denotes 6
T9749 20248-20250 IN denotes at
T9748 20242-20247 NN denotes ratio
T9747 20235-20241 JJ denotes higher
T9746 20227-20234 RB denotes 2.5fold
T9745 20225-20226 NN denotes –
T9744 20209-20224 JJ denotes non-significant
T9743 20207-20208 JJ denotes –
T9742 20205-20206 DT denotes a
T9741 20200-20204 RB denotes only
T9740 20198-20199 -COMMA- denotes ,
T9739 20193-20198 NN denotes ratio
T9738 20180-20192 NN denotes IL-1β/IL-1RA
T9737 20176-20179 DT denotes the
T9736 20173-20175 IN denotes in
T9735 20171-20172 NN denotes h
T9734 20168-20170 CD denotes 48
T9733 20165-20167 IN denotes of
T9732 20158-20164 NN denotes course
T9731 20153-20157 NN denotes time
T9730 20151-20152 DT denotes a
T9729 20146-20150 IN denotes over
T9728 20134-20145 NN denotes alterations
T9727 20122-20133 JJ denotes substantial
T9726 20117-20121 VB denotes find
T9725 20113-20116 RB denotes not
T9724 20109-20112 VB denotes did
T9723 20106-20108 PRP denotes we
T9722 20104-20105 -COMMA- denotes ,
T9721 20101-20104 NN denotes LPS
T9720 20099-20100 SYM denotes +
T9719 20096-20098 NN denotes GP
T9718 20092-20095 IN denotes vs.
T9717 20088-20091 NN denotes LPS
T9716 20078-20087 VB denotes Comparing
T9715 20075-20076 NN denotes h
T9714 20072-20074 CD denotes 24
T9713 20069-20071 TO denotes to
T9712 20066-20068 IN denotes up
T9711 20061-20065 FW denotes i.e.
T9710 20059-20060 -COMMA- denotes ,
T9709 20053-20059 NN denotes points
T9708 20048-20052 NN denotes time
T9707 20042-20047 JJ denotes early
T9706 20039-20041 IN denotes at
T9705 20032-20038 NN denotes IL-1RA
T9704 20027-20031 IN denotes than
T9703 20021-20026 NN denotes IL-1β
T9702 20016-20020 JJ denotes more
T9701 20005-20015 VB denotes generating
T9700 20002-20004 IN denotes in
T9699 19993-20001 VB denotes resulted
T9698 19982-19992 NN denotes treatments
T9697 19978-19981 NN denotes LPS
T9696 19976-19977 SYM denotes +
T9695 19973-19975 NN denotes GP
T9694 19969-19972 CC denotes and
T9693 19965-19968 NN denotes LPS
T9692 19963-19964 -COMMA- denotes ,
T9691 19959-19963 CC denotes Both
T9690 19945-19957 NN denotes inflammation
T9689 19942-19944 IN denotes of
T9688 19935-19941 NN denotes degree
T9687 19931-19934 DT denotes the
T9686 19928-19930 IN denotes of
T9685 19918-19927 NN denotes indicator
T9684 19915-19917 DT denotes an
T9683 19912-19914 IN denotes as
T9682 19906-19911 NN denotes ratio
T9681 19893-19905 NN denotes IL-1β/IL-1RA
T9680 19889-19892 DT denotes the
T9679 19881-19888 VB denotes applied
T9678 19878-19880 PRP denotes we
T9677 19876-19877 -COMMA- denotes ,
T9676 19867-19876 RB denotes Therefore
T9675 19859-19865 NN denotes action
T9674 19841-19858 JJ denotes anti-inflammatory
T9673 19838-19840 CC denotes or
T9672 19833-19837 FW denotes pro-
T9671 19828-19832 FW denotes i.e.
T9670 19826-19827 -COMMA- denotes ,
T9669 19822-19826 NN denotes coin
T9668 19820-19821 DT denotes a
T9667 19817-19819 IN denotes of
T9666 19811-19816 NN denotes sides
T9665 19807-19810 CD denotes two
T9664 19797-19806 VB denotes represent
T9663 19791-19796 MD denotes might
T9662 19784-19790 NN denotes IL-1RA
T9661 19780-19783 CC denotes and
T9660 19774-19779 NN denotes IL-1β
T9659 19772-19773 -COMMA- denotes ,
T9658 19764-19772 NN denotes approach
T9657 19753-19763 JJ denotes simplified
T9656 19751-19752 DT denotes a
T9655 19748-19750 IN denotes In
T9654 19738-19747 NN denotes phenotype
T9653 19720-19737 JJ denotes anti-inflammatory
T9652 19717-19719 DT denotes an
T9651 19709-19716 IN denotes towards
T9650 19703-19708 NN denotes ratio
T9649 19690-19702 NN denotes IL-1β/IL-1RA
T9648 19675-19689 JJ denotes TSST-1-induced
T9647 19671-19674 DT denotes the
T9646 19661-19670 VB denotes modulated
T9645 19658-19660 NN denotes GP
T8643 18479-18490 JJ denotes theoretical
T8642 18475-18478 DT denotes the
T8641 18470-18474 IN denotes from
T8640 18460-18469 JJ denotes different
T8639 18456-18459 RB denotes not
T8638 18451-18455 VB denotes were
T8637 18443-18450 NN denotes results
T8636 18430-18442 JJ denotes experimental
T8635 18426-18429 DT denotes the
T8634 18421-18425 FW denotes i.e.
T8633 18419-18420 -COMMA- denotes ,
T8632 18413-18419 NN denotes manner
T8631 18401-18412 JJ denotes synergistic
T8630 18392-18400 JJ denotes additive
T8629 18389-18391 DT denotes an
T8628 18386-18388 IN denotes in
T8627 18381-18385 RB denotes only
T8626 18377-18380 CC denotes but
T8625 18375-18376 -COMMA- denotes ,
T8624 18374-18375 -RRB- denotes )
T8623 18373-18374 CD denotes 5
T8622 18368-18372 NNP denotes Fig.
T8621 18366-18367 -COLON- denotes ;
T8620 18362-18366 CD denotes 0.05
T8619 18360-18361 SYM denotes <
T8618 18358-18359 NN denotes p
T8617 18357-18358 -LRB- denotes (
T8616 18348-18356 VB denotes elevated
T8615 18344-18347 VB denotes was
T8614 18342-18343 -RRB- denotes )
T8613 18336-18342 NN denotes TSST-1
T8612 18333-18335 IN denotes of
T8611 18324-18332 RB denotes 1.25fold
T8610 18322-18323 -COMMA- denotes ,
T8609 18320-18322 NN denotes GP
T8608 18317-18319 IN denotes of
T8607 18309-18316 CD denotes 1.5fold
T8606 18308-18309 -LRB- denotes (
T8605 18301-18307 NN denotes TSST-1
T8604 18299-18300 SYM denotes +
T8603 18296-18298 NN denotes GP
T8602 18292-18295 CC denotes and
T8601 18290-18291 -RRB- denotes )
T8600 18288-18290 NN denotes GP
T8599 18285-18287 IN denotes of
T8598 18277-18284 RB denotes 1.4fold
T8597 18276-18277 -LRB- denotes (
T8596 18272-18275 NN denotes LPS
T8595 18270-18271 SYM denotes +
T8594 18267-18269 NN denotes GP
T8593 18265-18266 -COMMA- denotes ,
T8592 18261-18265 CC denotes both
T8591 18251-18260 VB denotes following
T8590 18246-18250 NN denotes site
T8589 18237-18245 NN denotes NFATP2/3
T8588 18233-18236 DT denotes the
T8587 18230-18232 TO denotes to
T8586 18222-18229 VB denotes binding
T8585 18220-18221 -COMMA- denotes ,
T8584 18212-18220 NN denotes addition
T8583 18209-18211 IN denotes In
T8582 18206-18207 -RRB- denotes )
T8581 18202-18206 CD denotes 0.05
T8580 18200-18201 SYM denotes <
T8579 18198-18199 NN denotes p
T8578 18197-18198 -LRB- denotes (
T8577 18189-18196 NN denotes control
T8576 18182-18188 NN denotes medium
T8575 18179-18181 TO denotes to
T8574 18170-18178 VB denotes compared
T8573 18165-18169 WRB denotes when
T8491 17765-17768 CC denotes vs.
T8572 18163-18164 -COMMA- denotes ,
T8571 18151-18163 NN denotes combinations
T8570 18147-18150 CC denotes and
T8569 18137-18146 NN denotes compounds
T8568 18133-18136 DT denotes all
T8567 18129-18132 IN denotes for
T8566 18121-18128 NN denotes binding
T8565 18118-18120 IN denotes of
T8564 18109-18117 NN denotes increase
T8563 18097-18108 JJ denotes substantial
T8562 18095-18096 DT denotes a
T8561 18089-18094 RB denotes again
T8560 18078-18088 VB denotes displaying
T8559 18076-18077 -COMMA- denotes ,
T8558 18072-18076 CD denotes -490
T8557 18068-18071 CC denotes and
T8556 18063-18067 CD denotes -471
T8555 18055-18062 IN denotes between
T8554 18053-18054 -COMMA- denotes ,
T8553 18049-18053 NN denotes site
T8552 18043-18048 NN denotes start
T8551 18029-18042 NN denotes transcription
T8550 18025-18028 DT denotes the
T8549 18022-18024 IN denotes of
T8548 18015-18021 JJ denotes distal
T8547 18010-18014 RB denotes more
T8546 18004-18009 VB denotes found
T8545 18000-18003 VB denotes was
T8544 17991-17999 NN denotes NFATP2/3
T8543 17987-17990 IN denotes for
T8542 17982-17986 NN denotes site
T8541 17974-17981 NN denotes binding
T8540 17970-17973 JJ denotes new
T8539 17968-17969 DT denotes A
T8538 17965-17966 -RRB- denotes )
T8537 17960-17965 VB denotes shown
T8536 17956-17959 RB denotes not
T8535 17951-17955 NN denotes data
T8534 17950-17951 -LRB- denotes (
T8533 17948-17949 -COMMA- denotes ,
T8532 17947-17948 -RRB- denotes )
T8531 17943-17947 CD denotes 0.05
T8530 17941-17942 SYM denotes <
T8529 17939-17940 NN denotes p
T8528 17937-17938 -COLON- denotes ;
T8527 17930-17937 RB denotes 1.6fold
T8526 17929-17930 -LRB- denotes (
T8525 17926-17928 NN denotes GP
T8524 17923-17925 CC denotes or
T8523 17921-17922 -RRB- denotes )
T8522 17914-17921 RB denotes 1.3fold
T8521 17913-17914 -LRB- denotes (
T8520 17906-17912 NN denotes TSST-1
T8519 17901-17905 IN denotes with
T8518 17890-17900 NN denotes comparison
T8517 17887-17889 IN denotes in
T8516 17882-17886 NN denotes site
T8515 17875-17881 NN denotes NFIL-6
T8514 17871-17874 DT denotes the
T8513 17868-17870 TO denotes to
T8512 17860-17867 NN denotes binding
T8511 17850-17859 VB denotes increased
T8510 17847-17849 DT denotes an
T8509 17839-17846 VB denotes induced
T8508 17832-17838 NN denotes TSST-1
T8507 17830-17831 SYM denotes +
T8506 17827-17829 NN denotes GP
T8505 17825-17826 -COMMA- denotes ,
T8504 17818-17825 RB denotes Further
T8503 17815-17816 -RRB- denotes )
T8502 17811-17815 CD denotes 0.05
T8501 17809-17810 SYM denotes <
T8500 17807-17808 NN denotes p
T8499 17806-17807 -LRB- denotes (
T8498 17804-17805 NN denotes %
T8497 17798-17804 CD denotes 25–110
T8496 17793-17797 IN denotes from
T8495 17785-17792 VB denotes ranging
T8494 17783-17784 -COMMA- denotes ,
T8493 17776-17783 NN denotes control
T8492 17769-17775 NN denotes medium
T8490 17752-17764 NN denotes combinations
T8489 17748-17751 CC denotes and
T8488 17738-17747 NN denotes compounds
T8487 17734-17737 DT denotes all
T8486 17730-17733 IN denotes for
T8485 17722-17729 NN denotes binding
T8484 17719-17721 IN denotes of
T8483 17705-17718 NN denotes up-regulation
T8482 17702-17704 DT denotes an
T8481 17695-17701 VB denotes showed
T8480 17693-17694 -RRB- denotes ]
T8479 17688-17693 CD denotes 31,32
T8478 17687-17688 -LRB- denotes [
T8477 17681-17686 NN denotes LRE-2
T8476 17678-17680 TO denotes to
T8475 17672-17677 RB denotes close
T8474 17670-17671 -RRB- denotes )
T8473 17666-17670 CD denotes -170
T8472 17662-17665 CC denotes and
T8471 17657-17661 CD denotes -147
T8470 17656-17657 -LRB- denotes (
T8469 17651-17655 NN denotes site
T8468 17644-17650 NN denotes NFIL-6
T8467 17640-17643 DT denotes The
T8466 17637-17638 -RRB- denotes )
T8465 17632-17637 VB denotes shown
T8464 17628-17631 RB denotes not
T8463 17623-17627 NN denotes data
T8462 17621-17622 -COLON- denotes ;
T8461 17617-17621 CD denotes 0.05
T8460 17615-17616 SYM denotes <
T8459 17613-17614 NN denotes p
T8458 17612-17613 -LRB- denotes (
T8457 17604-17611 NN denotes control
T8456 17597-17603 NN denotes medium
T8455 17592-17596 IN denotes with
T8454 17581-17591 NN denotes comparison
T8453 17578-17580 IN denotes in
T8452 17576-17577 NN denotes %
T8451 17571-17576 CD denotes 20–35
T8450 17565-17570 RB denotes about
T8449 17562-17564 IN denotes by
T8448 17547-17561 VB denotes down-regulated
T8447 17543-17546 VB denotes was
T8446 17541-17542 -RRB- denotes )
T8445 17537-17541 CD denotes -302
T8444 17533-17536 CC denotes and
T8443 17528-17532 CD denotes -288
T8442 17527-17528 -LRB- denotes (
T8441 17522-17526 NN denotes site
T8440 17516-17521 NN denotes κB2/3
T8439 17512-17515 JJ denotes new
T8438 17508-17511 DT denotes the
T8437 17505-17507 TO denotes to
T8436 17497-17504 NN denotes binding
T8435 17485-17496 JJ denotes LPS-induced
T8434 17483-17484 CC denotes +
T8433 17480-17482 NN denotes GP
T8432 17476-17479 CC denotes and
T8431 17468-17475 NN denotes TSST-1-
T8430 17466-17467 -COMMA- denotes ,
T8429 17462-17466 NN denotes LPS-
T8428 17458-17461 DT denotes The
T8298 16861-16862 -COMMA- denotes ,
T8297 16853-16861 NN denotes activity
T8296 16845-16852 NN denotes binding
T8295 16841-16844 PRP-DOLLAR- denotes its
T8294 16838-16840 IN denotes of
T8293 16826-16837 NN denotes alterations
T8292 16814-16825 JJ denotes significant
T8291 16811-16813 DT denotes no
T8290 16807-16810 CC denotes but
T8289 16805-16806 -COMMA- denotes ,
T8288 16799-16805 NN denotes shifts
T8287 16794-16798 NN denotes band
T8286 16784-16793 VB denotes displayed
T8285 16782-16783 -RRB- denotes ]
T8284 16780-16782 CD denotes 30
T8283 16779-16780 -LRB- denotes [
T8282 16777-16778 -RRB- denotes )
T8281 16774-16777 CD denotes -93
T8280 16770-16773 CC denotes and
T8279 16766-16769 CD denotes -84
T8278 16758-16765 IN denotes between
T8277 16757-16758 -LRB- denotes (
T8276 16751-16756 NN denotes LRE-1
T8275 16748-16750 IN denotes of
T8274 16743-16747 NN denotes site
T8273 16733-16742 NN denotes consensus
T8272 16730-16732 NN denotes κB
T8271 16719-16729 JJ denotes responsive
T8270 16715-16718 NN denotes LPS
T8269 16711-16714 DT denotes The
T8268 16708-16709 -RRB- denotes )
T8267 16706-16708 NNP denotes UK
T8266 16704-16705 -COMMA- denotes ,
T8265 16698-16704 NNP denotes Oxford
T8264 16696-16697 -COMMA- denotes ,
T8263 16687-16696 NNP denotes Molecular
T8262 16680-16686 NNP denotes Oxford
T8261 16678-16679 -COMMA- denotes ,
T8260 16671-16678 NN denotes v.1.1.3
T8259 16670-16671 -LRB- denotes (
T8258 16664-16669 NN denotes OMIGA
T8257 16656-16663 NN denotes program
T8256 16652-16655 DT denotes the
T8255 16646-16651 VB denotes using
T8254 16644-16645 -RRB- denotes )
T8253 16643-16644 CD denotes 1
T8252 16637-16642 NN denotes Table
T8251 16636-16637 -LRB- denotes (
T8250 16627-16635 NN denotes promoter
T8249 16620-16626 NN denotes IL-1RA
T8248 16616-16619 DT denotes the
T8247 16613-16615 IN denotes of
T8246 16607-16612 NN denotes sites
T8245 16599-16606 NN denotes binding
T8244 16592-16598 NN denotes factor
T8243 16578-16591 NN denotes transcription
T8242 16567-16577 VB denotes discovered
T8241 16561-16566 RB denotes newly
T8240 16557-16560 CC denotes and
T8239 16547-16556 VB denotes described
T8238 16536-16546 JJ denotes previoulsy
T8237 16523-16535 VB denotes investigated
T8236 16520-16522 PRP denotes We
T8235 16510-16518 NN denotes promoter
T8234 16503-16509 NN denotes IL-1RA
T8233 16499-16502 DT denotes the
T8232 16496-16498 IN denotes in
T8231 16490-16495 NN denotes sites
T8230 16487-16489 TO denotes to
T8229 16482-16486 VB denotes bind
T8228 16476-16481 MD denotes might
T8227 16468-16475 NN denotes factors
T8226 16454-16467 NN denotes transcription
T8225 16444-16453 VB denotes activated
T8224 16440-16443 DT denotes the
T8223 16435-16439 IN denotes that
T8222 16422-16434 VB denotes hypothesized
T8221 16419-16421 PRP denotes we
T8220 16417-16418 -COMMA- denotes ,
T8219 16413-16417 NN denotes IFNγ
T8218 16410-16412 CC denotes or
T8217 16405-16409 NN denotes IL-6
T8216 16403-16404 -COMMA- denotes ,
T8215 16399-16403 NN denotes TNFα
T8214 16396-16398 DT denotes no
T8213 16392-16395 CC denotes but
T8212 16390-16391 -COMMA- denotes ,
T8211 16385-16390 NN denotes sites
T8210 16380-16384 NN denotes NFAT
T8209 16376-16379 CC denotes and
T8208 16369-16375 NN denotes NFIL-6
T8207 16367-16368 -COMMA- denotes ,
T8206 16363-16367 NN denotes NFκB
T8205 16360-16362 TO denotes to
T8204 16353-16359 NN denotes shifts
T8203 16348-16352 NN denotes band
T8202 16340-16347 VB denotes induced
T8201 16337-16339 NN denotes GP
T8200 16329-16336 IN denotes Because
T8199 16324-16328 NN denotes PBMC
T8198 16318-16323 JJ denotes human
T8197 16315-16317 IN denotes by
T8196 16304-16314 NN denotes expression
T8195 16297-16303 NN denotes IL-1RA
T8194 16282-16296 JJ denotes TSST-1-induced
T8193 16280-16281 CC denotes +
T8192 16277-16279 NN denotes GP
T8191 16273-16276 CC denotes and
T8190 16268-16272 NN denotes LPS-
T8189 16266-16267 SYM denotes +
T8188 16263-16265 NN denotes GP
T8187 16261-16262 -COMMA- denotes ,
T8186 16258-16261 NN denotes GP-
T8185 16256-16257 -COMMA- denotes ,
T8184 16249-16256 NN denotes TSST-1-
T8183 16247-16248 -COMMA- denotes ,
T8182 16243-16247 NN denotes LPS-
T8181 16240-16242 IN denotes in
T8180 16232-16239 NN denotes binding
T8179 16227-16231 NN denotes NFAT
T8178 16223-16226 CC denotes and
T8177 16216-16222 NN denotes NFIL-6
T8176 16214-16215 -COMMA- denotes ,
T8175 16210-16214 NN denotes NFκB
T8174 16207-16209 IN denotes of
T8173 16202-16206 NN denotes Role
T8647 18504-18505 -RRB- denotes )
T8646 18499-18504 NN denotes calc.
T8645 18498-18499 -LRB- denotes (
T8644 18491-18497 NN denotes values
T8427 17455-17456 -RRB- denotes )
T8426 17450-17455 VB denotes shown
T8425 17446-17449 RB denotes not
T8424 17441-17445 NN denotes data
T8423 17439-17440 -COLON- denotes ;
T8422 17435-17439 CD denotes 0.05
T8421 17433-17434 SYM denotes <
T8420 17431-17432 NN denotes p
T8419 17430-17431 -LRB- denotes (
T8418 17423-17429 NN denotes TSST-1
T8417 17421-17422 SYM denotes +
T8416 17418-17420 NN denotes GP
T8415 17414-17417 IN denotes for
T8414 17405-17413 VB denotes elevated
T8413 17391-17404 RB denotes significantly
T8412 17387-17390 VB denotes was
T8411 17385-17386 -RRB- denotes )
T8410 17381-17385 CD denotes -280
T8409 17377-17380 CC denotes and
T8408 17372-17376 CD denotes -266
T8407 17364-17371 IN denotes between
T8406 17363-17364 -LRB- denotes (
T8405 17358-17362 NN denotes site
T8404 17348-17357 NN denotes consensus
T8403 17345-17347 NN denotes κB
T8402 17341-17344 JJ denotes new
T8401 17339-17340 DT denotes a
T8400 17336-17338 TO denotes to
T8399 17328-17335 NN denotes Binding
T8398 17325-17326 -RRB- denotes )
T8397 17324-17325 CD denotes 4
T8396 17319-17323 NNP denotes Fig.
T8395 17317-17318 -COLON- denotes ;
T8394 17313-17317 CD denotes 0.05
T8393 17311-17312 SYM denotes <
T8392 17309-17310 NN denotes p
T8391 17305-17308 DT denotes all
T8390 17304-17305 -LRB- denotes (
T8389 17298-17303 NN denotes calc.
T8388 17288-17297 NN denotes GP/TSST-1
T8387 17285-17287 CC denotes or
T8386 17279-17284 NN denotes calc.
T8385 17272-17278 NN denotes GP/LPS
T8384 17269-17271 IN denotes of
T8383 17262-17268 NN denotes values
T8382 17250-17261 JJ denotes theoretical
T8381 17246-17249 DT denotes the
T8380 17243-17245 CC denotes or
T8379 17240-17242 NN denotes GP
T8378 17237-17239 CC denotes or
T8377 17230-17236 NN denotes TSST-1
T8376 17228-17229 -COMMA- denotes ,
T8375 17225-17228 NN denotes LPS
T8374 17222-17224 TO denotes to
T8373 17219-17221 IN denotes as
T8372 17214-17218 RB denotes well
T8371 17211-17213 RB denotes as
T8370 17203-17210 NN denotes control
T8369 17196-17202 NN denotes medium
T8368 17193-17195 TO denotes to
T8367 17184-17192 VB denotes compared
T8366 17179-17183 WRB denotes when
T8365 17177-17178 -COMMA- denotes ,
T8364 17170-17177 NN denotes fashion
T8363 17158-17169 JJ denotes synergistic
T8362 17144-17157 JJ denotes superadditive
T8361 17142-17143 DT denotes a
T8360 17139-17141 IN denotes in
T8359 17131-17138 NN denotes binding
T8358 17122-17130 JJ denotes -induced
T8357 17121-17122 -RRB- denotes )
T8356 17114-17121 NN denotes control
T8355 17110-17113 CC denotes vs.
T8354 17108-17109 NN denotes %
T8353 17104-17108 CD denotes +110
T8352 17103-17104 -LRB- denotes (
T8351 17096-17102 NN denotes TSST-1
T8350 17092-17095 DT denotes the
T8349 17088-17091 CC denotes and
T8348 17086-17087 -COLON- denotes -
T8347 17085-17086 -RRB- denotes )
T8346 17078-17085 NN denotes control
T8345 17074-17077 CC denotes vs.
T8344 17072-17073 NN denotes %
T8343 17069-17072 CD denotes +65
T8342 17068-17069 -LRB- denotes (
T8341 17064-17067 NN denotes LPS
T8340 17060-17063 DT denotes the
T8339 17047-17059 VB denotes up-regulated
T8338 17034-17046 NN denotes co-treatment
T8337 17031-17033 NN denotes GP
T8336 17027-17030 CC denotes but
T8335 17025-17026 -COMMA- denotes ,
T8334 17024-17025 -RRB- denotes )
T8333 17017-17024 NN denotes control
T8332 17013-17016 CC denotes vs.
T8331 17011-17012 NN denotes %
T8330 17008-17011 CD denotes +30
T8329 17007-17008 -LRB- denotes (
T8328 17000-17006 NN denotes TSST-1
T8327 16997-16999 IN denotes by
T8326 16989-16996 VB denotes induced
T8325 16981-16988 NN denotes binding
T8324 16971-16980 VB denotes increased
T8323 16964-16970 VB denotes showed
T8322 16962-16963 -RRB- denotes ]
T8321 16960-16962 CD denotes 30
T8320 16959-16960 -LRB- denotes [
T8319 16953-16958 NN denotes LRE-1
T8318 16949-16952 DT denotes the
T8317 16942-16948 IN denotes within
T8316 16940-16941 -RRB- denotes )
T8315 16936-16940 CD denotes -130
T8314 16932-16935 CC denotes and
T8313 16927-16931 CD denotes -100
T8312 16926-16927 -LRB- denotes (
T8311 16921-16925 NN denotes site
T8310 16917-16920 NN denotes κB3
T8309 16913-16916 JJ denotes new
T8308 16911-16912 DT denotes A
T8307 16908-16909 -RRB- denotes )
T8306 16903-16908 VB denotes shown
T8305 16899-16902 RB denotes not
T8304 16894-16898 NN denotes data
T8303 16893-16894 -LRB- denotes (
T8302 16883-16892 NN denotes treatment
T8301 16879-16882 DT denotes the
T8300 16876-16878 IN denotes of
T8299 16863-16875 JJ denotes irrespective
T6024 16198-16199 -RRB- denotes )
T6023 16193-16198 VB denotes shown
T6022 16189-16192 RB denotes not
T6021 16184-16188 NN denotes data
T6020 16183-16184 -LRB- denotes (
T6019 16181-16182 NN denotes h
T6018 16178-16180 CD denotes 48
T6017 16173-16177 IN denotes over
T6016 16167-16172 NN denotes calc.
T6015 16157-16166 NN denotes GP/TSST-1
T6014 16154-16156 CC denotes or
T6013 16147-16153 NN denotes TSST-1
T6012 16145-16146 SYM denotes +
T6011 16142-16144 NN denotes GP
T6010 16138-16141 CC denotes and
T6009 16132-16137 NN denotes calc.
T6008 16125-16131 NN denotes GP/LPS
T6007 16123-16124 -COMMA- denotes ,
T6006 16120-16123 NN denotes LPS
T6005 16118-16119 SYM denotes +
T6004 16115-16117 NN denotes GP
T6003 16113-16114 -COMMA- denotes ,
T6002 16111-16113 NN denotes GP
T6001 16109-16110 -COMMA- denotes ,
T6000 16103-16109 NN denotes TSST-1
T5999 16101-16102 -COMMA- denotes ,
T5998 16098-16101 NN denotes LPS
T5997 16096-16097 -COMMA- denotes ,
T5996 16089-16096 NN denotes control
T5995 16082-16088 NN denotes medium
T5994 16074-16081 IN denotes between
T5993 16062-16073 NN denotes differences
T5992 16050-16061 JJ denotes significant
T5991 16047-16049 DT denotes no
T5990 16042-16046 RB denotes also
T5989 16037-16041 VB denotes were
T5988 16031-16036 EX denotes There
T5987 16027-16029 NN denotes GP
T5986 16024-16026 IN denotes by
T5985 16016-16023 VB denotes induced
T5984 16012-16015 RB denotes not
T5983 16008-16011 VB denotes was
T5982 16006-16007 CD denotes 1
T5981 16001-16005 NN denotes TGFβ
T5980 15997-16000 CC denotes and
T5979 15991-15996 NN denotes IL-10
T5978 15989-15990 -COMMA- denotes ,
T5977 15985-15989 NN denotes IL-4
T5976 15983-15984 -COMMA- denotes ,
T5975 15978-15983 NN denotes IL-12
T5974 15976-15977 -COMMA- denotes ,
T5973 15972-15976 NN denotes IL-2
T5972 15969-15971 IN denotes of
T5971 15958-15968 NN denotes production
T5970 15954-15957 DT denotes The
T5969 15948-15953 NN denotes TGFβ1
T5968 15946-15947 -COMMA- denotes ,
T5967 15941-15946 NN denotes IL-10
T5966 15939-15940 -COMMA- denotes ,
T5965 15935-15939 NN denotes IL-4
T5964 15933-15934 -COMMA- denotes ,
T5963 15928-15933 NN denotes IL-12
T5962 15926-15927 -COMMA- denotes ,
T5961 15922-15926 NN denotes IL-2
T5960 15920-15921 -RRB- denotes )
T5959 15917-15920 LS denotes vii
T5958 15916-15917 -LRB- denotes (
T5957 15912-15913 -RRB- denotes )
T5956 15907-15912 VB denotes shown
T5955 15903-15906 RB denotes not
T5954 15898-15902 NN denotes data
T5953 15897-15898 -LRB- denotes (
T5952 15891-15896 NN denotes calc.
T5951 15881-15890 NN denotes GP/TSST-1
T5950 15878-15880 CC denotes or
T5949 15871-15877 NN denotes TSST-1
T5948 15868-15870 TO denotes to
T5947 15859-15867 VB denotes compared
T5946 15854-15858 WRB denotes when
T5945 15852-15853 -COMMA- denotes ,
T5944 15851-15852 NN denotes h
T5943 15848-15850 CD denotes 36
T5942 15844-15847 CC denotes and
T5941 15842-15843 NN denotes h
T5940 15839-15841 CD denotes 24
T5939 15836-15838 IN denotes at
T5938 15829-15835 NN denotes TSST-1
T5937 15827-15828 SYM denotes +
T5902 15652-15656 NN denotes PBMC
T5901 15649-15651 IN denotes of
T5900 15639-15648 NN denotes treatment
T5899 15629-15638 VB denotes following
T5898 15618-15628 JJ denotes detectable
T5897 15614-15617 VB denotes was
T5896 15603-15613 NN denotes production
T5895 15598-15602 NN denotes IFNγ
T5894 15595-15597 DT denotes No
T5893 15590-15594 NN denotes IFNγ
T5892 15588-15589 -RRB- denotes )
T5891 15586-15588 NN denotes vi
T5890 15585-15586 -LRB- denotes (
T5889 15581-15582 -RRB- denotes )
T5888 15575-15581 NN denotes detail
T5887 15572-15574 IN denotes in
T5886 15566-15571 VB denotes shown
T5885 15562-15565 RB denotes not
T5884 15557-15561 NN denotes data
T5883 15555-15556 -COLON- denotes ;
T5882 15551-15555 CD denotes 0.05
T5881 15549-15550 SYM denotes >
T5880 15547-15548 NN denotes p
T5879 15546-15547 -LRB- denotes (
T5878 15537-15545 VB denotes observed
T5877 15533-15536 VB denotes was
T5876 15531-15532 NN denotes %
T5875 15529-15531 CD denotes 10
T5874 15524-15528 RB denotes only
T5873 15521-15523 IN denotes of
T5872 15509-15520 NN denotes enhancement
T5871 15506-15508 DT denotes an
T5870 15498-15505 RB denotes overall
T5869 15494-15497 CC denotes but
T5868 15492-15493 -COMMA- denotes ,
T5867 15491-15492 -RRB- denotes )
T5866 15487-15491 CD denotes 0.05
T5865 15485-15486 SYM denotes <
T5864 15483-15484 NN denotes p
T5863 15481-15482 -COLON- denotes ;
T5862 15480-15481 CD denotes 3
T5861 15478-15479 SYM denotes =
T5860 15476-15477 NN denotes n
T5859 15475-15476 -LRB- denotes (
T5858 15473-15474 NN denotes h
T5857 15470-15472 CD denotes 36
T5856 15464-15469 IN denotes after
T5855 15454-15463 NN denotes secretion
T5854 15449-15453 NN denotes TNFα
T5853 15446-15448 IN denotes on
T5852 15439-15445 NN denotes effect
T5851 15427-15438 JJ denotes synergistic
T5850 15425-15426 DT denotes a
T5849 15419-15424 VB denotes exert
T5848 15416-15418 TO denotes to
T5847 15409-15415 VB denotes seemed
T5846 15406-15408 NN denotes GP
T5845 15404-15405 -COMMA- denotes ,
T5844 15399-15404 NN denotes calc.
T5843 15389-15398 NN denotes GP/TSST-1
T5842 15386-15388 CC denotes or
T5841 15379-15385 NN denotes TSST-1
T5840 15374-15378 IN denotes with
T5839 15365-15373 VB denotes combined
T5838 15360-15364 WRB denotes When
T5837 15354-15358 NN denotes calc
T5836 15347-15353 NN denotes GP/LPS
T5835 15344-15346 CC denotes or
T5834 15328-15343 NN denotes supplementation
T5833 15324-15327 NN denotes LPS
T5832 15321-15323 TO denotes to
T5831 15312-15320 VB denotes compared
T5830 15307-15311 WRB denotes when
T5829 15296-15306 NN denotes production
T5828 15291-15295 NN denotes TNFα
T5827 15287-15290 DT denotes the
T5826 15280-15286 VB denotes change
T5825 15276-15279 RB denotes not
T5824 15272-15275 VB denotes did
T5823 15268-15271 NN denotes LPS
T5822 15266-15267 SYM denotes +
T5821 15263-15265 NN denotes GP
T5820 15254-15261 NN denotes control
T5819 15247-15253 NN denotes medium
T5818 15244-15246 TO denotes to
T5817 15235-15243 VB denotes compared
T5816 15230-15234 WRB denotes when
T5815 15228-15229 -COMMA- denotes ,
T5814 15221-15228 NN denotes amounts
T5813 15205-15220 JJ denotes distinguishable
T5812 15201-15204 RB denotes not
T5811 15187-15200 RB denotes statistically
T5810 15185-15186 -COMMA- denotes ,
T5809 15180-15185 JJ denotes minor
T5808 15172-15179 VB denotes yielded
T5807 15169-15171 NN denotes GP
T5806 15166-15168 IN denotes of
T5805 15163-15165 NN denotes μg
T5804 15159-15162 CD denotes 100
T5803 15157-15158 -COMMA- denotes ,
T5802 15147-15157 NN denotes production
T5801 15142-15146 NN denotes TNFα
T5800 15139-15141 TO denotes to
T5799 15131-15138 NN denotes respect
T5798 15126-15130 IN denotes With
T5797 15121-15125 NN denotes TNFα
T5796 15119-15120 -RRB- denotes )
T5795 15118-15119 NN denotes v
T5794 15117-15118 -LRB- denotes (
T5793 15113-15114 -RRB- denotes )
T5792 15101-15113 RB denotes respectively
T5791 15099-15100 -COMMA- denotes ,
T5790 15095-15099 CD denotes 0.98
T5789 15091-15094 CC denotes and
T5788 15087-15090 CD denotes 0.9
T5787 15085-15086 SYM denotes =
T5786 15083-15084 NN denotes r
T5785 15081-15082 -COMMA- denotes ,
T5784 15076-15081 CD denotes 0.002
T5783 15074-15075 -COMMA- denotes ≤
T5782 15072-15073 NN denotes p
T5781 15070-15071 -COMMA- denotes ,
T5780 15069-15070 CD denotes 5
T5779 15067-15068 SYM denotes =
T5778 15065-15066 NN denotes n
T5777 15064-15065 -LRB- denotes (
T5776 15061-15063 NN denotes GP
T5775 15058-15060 NN denotes μg
T5774 15056-15057 CD denotes 1
T5773 15051-15055 IN denotes than
T5772 15044-15050 NN denotes IL-1RA
T5771 15040-15043 CC denotes and
T5770 15035-15039 NN denotes IL-8
T5769 15032-15034 IN denotes of
T5768 15024-15031 NN denotes amounts
T5767 15017-15023 JJ denotes larger
T5766 15009-15016 VB denotes induced
T5765 15006-15008 NN denotes GP
T5764 15003-15005 IN denotes of
T5763 15000-15002 NN denotes μg
T5762 14996-14999 CD denotes 100
T5761 14990-14995 IN denotes since
T5760 14988-14989 -COMMA- denotes ,
T5759 14974-14988 JJ denotes dose-dependent
T5758 14971-14973 VB denotes be
T5757 14968-14970 TO denotes to
T5756 14956-14967 NN denotes correlation
T5755 14951-14955 DT denotes this
T5754 14945-14950 VB denotes found
T5753 14942-14944 PRP denotes we
T5752 14940-14941 -COMMA- denotes ,
T5751 14932-14940 RB denotes Moreover
T5750 14924-14930 NN denotes IL-1RA
T5749 14920-14923 CC denotes and
T5748 14915-14919 NN denotes IL-8
T5747 14907-14914 IN denotes between
T5746 14895-14906 NN denotes correlation
T5745 14886-14894 JJ denotes positive
T5744 14884-14885 DT denotes a
T5743 14875-14883 VB denotes observed
T5742 14872-14874 PRP denotes we
T5741 14870-14871 -COMMA- denotes ,
T5740 14869-14870 -RRB- denotes )
T5739 14868-14869 NN denotes h
T5738 14865-14867 CD denotes 24
T5737 14864-14865 -LRB- denotes (
T5736 14861-14863 NN denotes GP
T5735 14856-14860 IN denotes with
T5734 14844-14855 NN denotes stimulation
T5733 14834-14843 VB denotes Following
T5732 14821-14832 NN denotes productions
T5731 14814-14820 NN denotes IL-1RA
T5730 14810-14813 CC denotes and
T5729 14805-14809 NN denotes IL-8
T5728 14794-14804 JJ denotes GP-induced
T5727 14786-14793 IN denotes between
T5726 14774-14785 NN denotes correlation
T5725 14765-14773 JJ denotes Positive
T5724 14762-14763 -RRB- denotes )
T5723 14760-14762 NN denotes 3B
T5722 14755-14759 NN denotes Fig.
T5721 14754-14755 -LRB- denotes (
T5720 14752-14753 NN denotes %
T5719 14749-14752 CD denotes 200
T5718 14735-14748 RB denotes approximately
T5717 14732-14734 IN denotes by
T5716 14725-14731 NN denotes IL-1RA
T5715 14722-14724 IN denotes of
T5714 14715-14721 NN denotes amount
T5713 14700-14714 JJ denotes TSST-1-induced
T5712 14696-14699 DT denotes the
T5711 14687-14695 VB denotes elevated
T5710 14684-14686 NN denotes GP
T5709 14682-14683 -COMMA- denotes ,
T5708 14681-14682 NN denotes h
T5707 14678-14680 CD denotes 48
T5706 14675-14677 IN denotes of
T5705 14668-14674 NN denotes course
T5704 14663-14667 NN denotes time
T5703 14659-14662 DT denotes the
T5702 14654-14658 IN denotes Over
T5701 14651-14652 -RRB- denotes )
T5700 14650-14651 NN denotes h
T5699 14647-14649 CD denotes 36
T5698 14644-14646 TO denotes to
T5697 14642-14643 NN denotes h
T5696 14639-14641 CD denotes 18
T5695 14634-14638 IN denotes from
T5694 14633-14634 -LRB- denotes (
T5693 14627-14632 NN denotes calc.
T5692 14617-14626 NN denotes GP/TSST-1
T5691 14614-14616 IN denotes of
T5690 14608-14613 NN denotes value
T5689 14596-14607 JJ denotes theoretical
T5688 14592-14595 DT denotes the
T5687 14589-14591 TO denotes to
T5636 14360-14363 VB denotes did
T5635 14356-14359 NN denotes LPS
T5634 14354-14355 SYM denotes +
T5633 14351-14353 NN denotes GP
T5632 14349-14350 -COMMA- denotes ,
T5631 14344-14349 NN denotes calc.
T5630 14337-14343 NN denotes GP/LPS
T5629 14334-14336 CC denotes or
T5628 14322-14333 NN denotes stimulation
T5627 14318-14321 NN denotes LPS
T5626 14315-14317 TO denotes to
T5625 14306-14314 VB denotes compared
T5624 14301-14305 WRB denotes When
T5623 14298-14299 -RRB- denotes )
T5622 14294-14298 CD denotes 0.01
T5621 14292-14293 SYM denotes <
T5620 14290-14291 NN denotes p
T5619 14288-14289 -COMMA- denotes ,
T5618 14286-14288 CD denotes 14
T5617 14284-14285 SYM denotes =
T5616 14282-14283 NN denotes n
T5615 14281-14282 -LRB- denotes (
T5614 14279-14280 NN denotes h
T5613 14276-14278 CD denotes 24
T5612 14273-14275 IN denotes at
T5611 14262-14272 RB denotes especially
T5610 14260-14261 -COMMA- denotes ,
T5609 14251-14260 NN denotes treatment
T5608 14248-14250 NN denotes GP
T5607 14238-14247 VB denotes following
T5606 14227-14237 NN denotes quantities
T5605 14215-14226 JJ denotes significant
T5604 14212-14214 IN denotes in
T5603 14203-14211 VB denotes produced
T5602 14199-14202 VB denotes was
T5601 14193-14198 WDT denotes which
T5600 14184-14192 NN denotes mediator
T5599 14179-14183 JJ denotes only
T5598 14175-14178 DT denotes the
T5597 14171-14174 VB denotes was
T5596 14164-14170 NN denotes IL-1RA
T5595 14162-14163 -COMMA- denotes ,
T5594 14158-14162 NN denotes IL-8
T5593 14150-14157 IN denotes Besides
T5592 14143-14149 NN denotes IL-1RA
T5591 14141-14142 -RRB- denotes )
T5590 14139-14141 LS denotes iv
T5589 14138-14139 -LRB- denotes (
T5588 14134-14135 -RRB- denotes )
T5587 14128-14134 NN denotes detail
T5586 14125-14127 IN denotes in
T5585 14119-14124 VB denotes shown
T5584 14115-14118 RB denotes not
T5583 14110-14114 NN denotes data
T5582 14109-14110 -LRB- denotes (
T5581 14103-14108 NN denotes calc.
T5580 14093-14102 NN denotes GP/TSST-1
T5579 14090-14092 CC denotes or
T5578 14083-14089 NN denotes TSST-1
T5577 14080-14082 TO denotes to
T5576 14071-14079 VB denotes compared
T5575 14066-14070 WRB denotes when
T5574 14059-14065 NN denotes TSST-1
T5573 14057-14058 SYM denotes +
T5572 14054-14056 NN denotes GP
T5571 14044-14053 VB denotes following
T5570 14033-14043 NN denotes production
T5569 14028-14032 NN denotes IL-8
T5568 14025-14027 IN denotes in
T5567 14014-14024 NN denotes alteration
T5566 14002-14013 JJ denotes significant
T5565 13999-14001 DT denotes no
T5564 13995-13998 VB denotes was
T5563 13989-13994 EX denotes There
T5562 13983-13987 NN denotes calc
T5561 13976-13982 NN denotes GP/LPS
T5560 13973-13975 CC denotes or
T5559 13969-13972 NN denotes LPS
T5558 13966-13968 TO denotes to
T5557 13957-13965 VB denotes compared
T5556 13952-13956 WRB denotes when
T5555 13941-13951 NN denotes production
T5554 13936-13940 NN denotes IL-8
T5553 13933-13935 IN denotes of
T5552 13924-13932 NN denotes increase
T5551 13908-13923 JJ denotes non-significant
T5550 13906-13907 DT denotes a
T5549 13903-13905 IN denotes in
T5548 13894-13902 VB denotes resulted
T5547 13890-13893 NN denotes LPS
T5546 13886-13889 CC denotes and
T5545 13883-13885 NN denotes GP
T5544 13880-13882 IN denotes of
T5543 13868-13879 NN denotes combination
T5542 13866-13867 DT denotes A
T5541 13863-13864 -RRB- denotes )
T5540 13859-13863 CD denotes 0.01
T5539 13857-13858 SYM denotes <
T5538 13855-13856 NN denotes p
T5537 13853-13854 -COLON- denotes ;
T5536 13851-13853 CD denotes 13
T5535 13849-13850 SYM denotes =
T5534 13847-13848 NN denotes n
T5533 13846-13847 -LRB- denotes (
T5532 13844-13845 NN denotes h
T5531 13841-13843 CD denotes 24
T5530 13838-13840 IN denotes at
T5529 13827-13837 RB denotes especially
T5528 13825-13826 -COMMA- denotes ,
T5527 13818-13825 NN denotes control
T5526 13811-13817 NN denotes medium
T5525 13806-13810 IN denotes with
T5524 13795-13805 NN denotes comparison
T5523 13792-13794 IN denotes in
T5522 13790-13791 -COMMA- denotes ,
T5521 13780-13790 NN denotes production
T5520 13775-13779 NN denotes IL-8
T5519 13763-13774 JJ denotes substantial
T5518 13761-13762 DT denotes a
T5517 13753-13760 VB denotes induced
T5516 13750-13752 NN denotes GP
T5515 13745-13749 IN denotes that
T5514 13739-13744 VB denotes found
T5513 13736-13738 PRP denotes We
T5512 13731-13735 NN denotes IL-8
T5511 13729-13730 -RRB- denotes )
T5510 13726-13729 LS denotes iii
T5509 13725-13726 -LRB- denotes (
T5508 13721-13722 -RRB- denotes )
T5507 13715-13721 NN denotes detail
T5506 13712-13714 IN denotes in
T5505 13706-13711 VB denotes shown
T5504 13702-13705 RB denotes not
T5503 13697-13701 NN denotes data
T5502 13696-13697 -LRB- denotes (
T5501 13694-13695 -COMMA- denotes ,
T5500 13693-13694 -RRB- denotes )
T5499 13689-13693 CD denotes 0.02
T5498 13687-13688 SYM denotes =
T5497 13685-13686 NN denotes p
T5496 13680-13684 CC denotes both
T5495 13678-13679 -COLON- denotes ;
T5494 13677-13678 CD denotes 5
T5493 13675-13676 SYM denotes =
T5492 13673-13674 NN denotes n
T5491 13672-13673 -LRB- denotes (
T5490 13670-13671 NN denotes %
T5489 13668-13670 CD denotes 40
T5488 13662-13667 RB denotes about
T5487 13659-13661 IN denotes by
T5486 13657-13658 NN denotes h
T5485 13654-13656 CD denotes 24
T5484 13651-13653 IN denotes at
T5483 13640-13650 RB denotes especially
T5482 13638-13639 -COMMA- denotes ,
T5481 13633-13638 NN denotes calc.
T5480 13623-13632 NN denotes GP/TSST-1
T5479 13620-13622 CC denotes or
T5478 13613-13619 NN denotes TSST-1
T5477 13610-13612 TO denotes to
T5476 13601-13609 VB denotes compared
T5475 13596-13600 WRB denotes when
T5474 13589-13595 NN denotes TSST-1
T5473 13587-13588 SYM denotes +
T5472 13584-13586 NN denotes GP
T5471 13580-13583 IN denotes for
T5470 13569-13579 NN denotes production
T5469 13564-13568 NN denotes IL-6
T5468 13554-13563 VB denotes decreased
T5467 13552-13553 DT denotes a
T5466 13543-13551 VB denotes observed
T5465 13540-13542 PRP denotes we
T5464 13538-13539 -COMMA- denotes ,
T5463 13530-13538 NN denotes contrary
T5462 13526-13529 DT denotes the
T5461 13523-13525 IN denotes On
T5460 13519-13521 NN denotes GP
T5459 13516-13518 IN denotes by
T5458 13505-13515 NN denotes production
T5457 13500-13504 NN denotes IL-6
T5456 13488-13499 JJ denotes LPS-induced
T5455 13484-13487 DT denotes the
T5454 13481-13483 IN denotes of
T5453 13470-13480 NN denotes alteration
T5452 13458-13469 JJ denotes significant
T5451 13455-13457 DT denotes no
T5450 13451-13454 VB denotes was
T5449 13445-13450 EX denotes there
T5448 13441-13444 CC denotes and
T5447 13436-13440 NN denotes IL-6
T5936 15824-15826 NN denotes GP
T5935 15814-15823 VB denotes following
T5934 15798-15813 NN denotes down-regulation
T5933 15791-15797 JJ denotes slight
T5932 15789-15790 DT denotes a
T5931 15785-15788 CC denotes and
T5930 15783-15784 -COMMA- denotes ,
T5929 15778-15783 NN denotes calc.
T5928 15771-15777 NN denotes GP/LPS
T5927 15768-15770 CC denotes or
T5926 15764-15767 NN denotes LPS
T5925 15761-15763 TO denotes to
T5924 15752-15760 VB denotes compared
T5923 15747-15751 WRB denotes when
T5922 15745-15746 -COMMA- denotes ,
T5921 15744-15745 NN denotes h
T5920 15741-15743 CD denotes 36
T5919 15738-15740 IN denotes at
T5918 15734-15737 NN denotes LPS
T5917 15732-15733 SYM denotes +
T5916 15729-15731 NN denotes GP
T5915 15719-15728 VB denotes following
T5914 15708-15718 NN denotes production
T5913 15703-15707 NN denotes IFNγ
T5912 15700-15702 IN denotes in
T5911 15691-15699 NN denotes increase
T5910 15685-15690 JJ denotes minor
T5909 15683-15684 DT denotes a
T5908 15679-15682 VB denotes was
T5907 15673-15678 EX denotes There
T5906 15669-15671 NN denotes GP
T5905 15666-15668 NN denotes μg
T5904 15662-15665 CD denotes 100
T5903 15657-15661 IN denotes with
T5446 13433-13435 IN denotes of
T5445 13426-13432 NN denotes amount
T5444 13420-13425 JJ denotes small
T5443 13418-13419 DT denotes a
T5442 13413-13417 RB denotes only
T5441 13405-13412 VB denotes induced
T5440 13402-13404 NN denotes GP
T5439 13397-13401 NN denotes IL-6
T5438 13395-13396 -RRB- denotes )
T5437 13393-13395 LS denotes ii
T5436 13392-13393 -LRB- denotes (
T5435 12173-12174 -RRB- denotes )
T5434 12171-12173 NN denotes 3A
T5433 12166-12170 NN denotes Fig.
T5432 12165-12166 -LRB- denotes (
T5431 12163-12164 NN denotes %
T5430 12161-12163 CD denotes 50
T5429 12155-12160 RB denotes about
T5428 12152-12154 IN denotes by
T5427 12146-12151 NN denotes IL-1β
T5426 12143-12145 IN denotes of
T5425 12136-12142 NN denotes amount
T5424 12121-12135 JJ denotes TSST-1-induced
T5423 12117-12120 DT denotes the
T5422 12114-12116 IN denotes of
T5421 12104-12113 NN denotes reduction
T5379 11938-11942 IN denotes from
T5378 11932-11937 NN denotes IL-1β
T5377 11929-11931 IN denotes in
T5376 11919-11928 NN denotes reduction
T5375 11907-11918 JJ denotes significant
T5374 11905-11906 DT denotes a
T5373 11899-11904 VB denotes found
T5372 11896-11898 PRP denotes we
T5371 11889-11895 NN denotes TSST-1
T5370 11887-11888 SYM denotes +
T5369 11884-11886 NN denotes GP
T5368 11880-11883 IN denotes For
T5367 11875-11878 NN denotes LPS
T5366 11870-11874 IN denotes with
T5365 11859-11869 NN denotes comparison
T5364 11856-11858 IN denotes in
T5363 11847-11855 VB denotes observed
T5362 11843-11846 VB denotes was
T5361 11839-11842 NN denotes LPS
T5360 11837-11838 SYM denotes +
T5359 11834-11836 NN denotes GP
T5358 11830-11833 IN denotes for
T5357 11819-11829 NN denotes production
T5356 11813-11818 NN denotes IL-1β
T5355 11810-11812 IN denotes of
T5354 11796-11809 NN denotes up-regulation
T5353 11782-11795 JJ denotes insignificant
T5352 11779-11781 DT denotes An
T5351 11775-11777 NN denotes GP
T5350 11772-11774 NN denotes μg
T5349 11768-11771 CD denotes 100
T5348 11764-11767 CC denotes nor
T5347 11762-11763 CD denotes 1
T5346 11757-11761 IN denotes with
T5345 11747-11756 NN denotes treatment
T5344 11742-11746 NN denotes PBMC
T5343 11732-11741 VB denotes following
T5342 11721-11731 JJ denotes detectable
T5341 11710-11720 NN denotes production
T5340 11704-11709 NN denotes IL-1β
T5339 11701-11703 DT denotes no
T5338 11697-11700 VB denotes was
T5337 11691-11696 EX denotes There
T5336 11685-11690 NN denotes IL-1β
T5335 11683-11684 -RRB- denotes )
T5334 11682-11683 LS denotes i
T5333 11681-11682 -LRB- denotes (
T5332 11678-11679 -COLON- denotes :
T5331 11677-11678 -RRB- denotes )
T5330 11671-11677 NN denotes TSST-1
T5329 11669-11670 -COMMA- denotes ,
T5328 11666-11669 NN denotes LPS
T5327 11665-11666 -LRB- denotes (
T5326 11655-11664 NN denotes mediators
T5325 11638-11654 JJ denotes pro-inflammatory
T5324 11634-11637 CD denotes two
T5323 11631-11633 TO denotes to
T5322 11620-11630 NN denotes comparison
T5321 11617-11619 IN denotes in
T5320 11613-11616 CC denotes and
T5319 11598-11612 NN denotes β-1→3-D-glucan
T5318 11590-11597 JJ denotes soluble
T5317 11584-11589 NN denotes water
T5316 11575-11583 VB denotes purified
T5315 11568-11574 RB denotes highly
T5314 11566-11567 DT denotes a
T5313 11563-11565 TO denotes to
T5312 11554-11562 NN denotes response
T5311 11551-11553 IN denotes in
T5310 11540-11550 NN denotes leukocytes
T5309 11534-11539 JJ denotes human
T5308 11531-11533 IN denotes of
T5307 11523-11530 NN denotes profile
T5306 11514-11522 NN denotes cytokine
T5305 11504-11513 VB denotes following
T5304 11500-11503 DT denotes the
T5303 11491-11499 VB denotes revealed
T5302 11482-11490 NN denotes analysis
T5301 11468-11481 JJ denotes comprehensive
T5300 11464-11467 PRP-DOLLAR- denotes our
T5299 11462-11463 -COMMA- denotes ,
T5298 11457-11462 NN denotes sites
T5297 11449-11456 NN denotes binding
T5296 11442-11448 NN denotes factor
T5295 11428-11441 NN denotes transcription
T5294 11417-11427 JJ denotes additional
T5293 11413-11416 CD denotes six
T5292 11409-11412 CC denotes and
T5291 11407-11408 -RRB- denotes )
T5290 11406-11407 NN denotes h
T5289 11403-11405 CD denotes 48
T5288 11402-11403 -LRB- denotes (
T5287 11397-11401 NN denotes time
T5286 11392-11396 IN denotes over
T5285 11382-11391 NN denotes cytokines
T5284 11369-11381 JJ denotes inflammatory
T5283 11367-11368 -RRB- denotes )
T5282 11362-11367 CD denotes three
T5281 11361-11362 -LRB- denotes (
T5280 11355-11360 JJ denotes anti-
T5279 11352-11354 IN denotes as
T5278 11347-11351 RB denotes well
T5277 11344-11346 RB denotes as
T5276 11342-11343 -RRB- denotes )
T5275 11337-11342 CD denotes eight
T5274 11336-11337 -LRB- denotes (
T5273 11331-11335 JJ denotes pro-
T5272 11321-11330 VB denotes examining
T5271 11318-11320 IN denotes of
T5270 11312-11317 NN denotes terms
T5269 11309-11311 IN denotes in
T5268 11300-11308 NN denotes findings
T5267 11291-11299 JJ denotes singular
T5266 11285-11290 DT denotes these
T5265 11275-11284 VB denotes extending
T5264 11271-11274 CC denotes and
T5263 11257-11270 VB denotes Corroborating
T5262 11254-11255 -RRB- denotes ]
T5261 11249-11254 CD denotes 15-18
T5260 11248-11249 -LRB- denotes [
T5259 11242-11247 NN denotes cells
T5258 11236-11241 NN denotes blood
T5257 11230-11235 JJ denotes human
T5256 11227-11229 IN denotes of
T5255 11217-11226 NN denotes secretion
T5254 11208-11216 NN denotes cytokine
T5253 11200-11207 JJ denotes limited
T5252 11198-11199 DT denotes a
T5251 11193-11197 RB denotes only
T5250 11185-11192 VB denotes induced
T5249 11169-11184 NN denotes β-1→3-D-glucans
T5248 11164-11168 IN denotes that
T5247 11155-11163 VB denotes reported
T5246 11147-11154 NN denotes studies
T5245 11138-11146 JJ denotes Previous
T5244 11127-11136 NN denotes mediators
T5243 11110-11126 JJ denotes pro-inflammatory
T5242 11104-11109 JJ denotes other
T5241 11100-11103 CC denotes and
T5240 11095-11099 NN denotes IFNγ
T5239 11093-11094 -COMMA- denotes ,
T5238 11089-11093 NN denotes IL-6
T5237 11087-11088 -COMMA- denotes ,
T5236 11083-11087 NN denotes IL-8
T5235 11081-11082 -COMMA- denotes ,
T5234 11077-11081 NN denotes TNFα
T5233 11074-11076 IN denotes of
T5232 11063-11073 NN denotes production
T5231 11060-11062 TO denotes to
T5230 11055-11059 VB denotes lead
T5229 11049-11054 MD denotes would
T5228 11044-11048 NN denotes PBMC
T5227 11038-11043 JJ denotes human
T5226 11035-11037 IN denotes of
T5225 11025-11034 NN denotes treatment
T5224 11022-11024 NN denotes GP
T5223 11017-11021 IN denotes that
T5222 11009-11016 VB denotes assumed
T5221 11006-11008 VB denotes be
T5220 11000-11005 MD denotes could
T5219 10997-10999 PRP denotes it
T5218 10995-10996 -COMMA- denotes ,
T5217 10986-10995 NN denotes promoters
T5216 10981-10985 NN denotes IFNγ
T5215 10977-10980 CC denotes and
T5214 10972-10976 NN denotes IL-6
T5213 10970-10971 -COMMA- denotes ,
T5212 10966-10970 NN denotes IL-8
T5211 10964-10965 -COMMA- denotes ,
T5210 10960-10964 NN denotes TNFα
T5209 10956-10959 DT denotes the
T5208 10951-10955 IN denotes from
T5207 10945-10950 NN denotes sites
T5206 10939-10944 CD denotes seven
T5205 10936-10938 TO denotes to
T5204 10929-10935 NN denotes shifts
T5203 10924-10928 NN denotes band
T5202 10913-10923 JJ denotes GP-induced
T5201 10909-10912 DT denotes the
T5200 10906-10908 IN denotes of
T5199 10898-10905 IN denotes Because
T5198 10891-10897 NN denotes TSST-1
T5197 10889-10890 SYM denotes +
T5196 10886-10888 NN denotes GP
T5195 10882-10885 CC denotes and
T5194 10878-10881 NN denotes LPS
T5193 10876-10877 SYM denotes +
T5192 10873-10875 NN denotes GP
T5191 10871-10872 -COMMA- denotes ,
T5190 10869-10871 NN denotes GP
T5686 14586-14588 CC denotes or
T5685 14584-14585 -RRB- denotes )
T5684 14580-14584 CD denotes 0.01
T5683 14578-14579 SYM denotes =
T5682 14576-14577 NN denotes p
T5681 14574-14575 -COLON- denotes ;
T5680 14573-14574 CD denotes 6
T5679 14571-14572 JJ denotes =
T5678 14569-14570 NN denotes n
T5677 14567-14568 -COLON- denotes :
T5676 14566-14567 NN denotes h
T5675 14563-14565 CD denotes 24
T5674 14560-14562 IN denotes at
T5673 14551-14559 NN denotes instance
T5672 14547-14550 IN denotes for
T5671 14546-14547 -LRB- denotes (
T5670 14539-14545 NN denotes TSST-1
T5669 14536-14538 TO denotes to
T5668 14527-14535 VB denotes compared
T5667 14522-14526 WRB denotes when
T5666 14520-14521 -COMMA- denotes ,
T5665 14519-14520 NN denotes h
T5664 14516-14518 CD denotes 48
T5663 14513-14515 TO denotes to
T5662 14511-14512 NN denotes h
T5661 14508-14510 CD denotes 18
T5660 14503-14507 IN denotes from
T5659 14492-14502 NN denotes production
T5658 14485-14491 NN denotes IL-1RA
T5657 14482-14484 IN denotes in
T5656 14473-14481 NN denotes increase
T5655 14461-14472 JJ denotes synergistic
T5654 14459-14460 DT denotes a
T5653 14453-14458 VB denotes found
T5652 14450-14452 PRP denotes we
T5651 14443-14449 NN denotes TSST-1
T5650 14441-14442 SYM denotes +
T5649 14438-14440 NN denotes GP
T5648 14428-14437 VB denotes following
T5647 14426-14427 -COMMA- denotes ,
T5646 14419-14426 RB denotes However
T5645 14407-14417 NN denotes production
T5644 14400-14406 NN denotes IL-1RA
T5643 14396-14399 DT denotes the
T5642 14393-14395 IN denotes of
T5641 14386-14392 NN denotes course
T5640 14378-14385 JJ denotes kinetic
T5639 14374-14377 DT denotes the
T5638 14368-14373 VB denotes alter
T5637 14364-14367 RB denotes not
T5189 10867-10868 -COMMA- denotes ,
T5188 10861-10867 NN denotes TSST-1
T5187 10859-10860 -COMMA- denotes ,
T5186 10856-10859 NN denotes LPS
T5185 10851-10855 IN denotes with
T5184 10839-10850 NN denotes stimulation
T5183 10833-10838 FW denotes vitro
T5182 10830-10832 FW denotes in
T5181 10828-10829 NN denotes h
T5180 10825-10827 CD denotes 48
T5179 10823-10824 DT denotes a
T5178 10813-10822 VB denotes following
T5177 10808-10812 NN denotes PBMC
T5176 10802-10807 JJ denotes human
T5175 10799-10801 IN denotes of
T5174 10791-10798 NN denotes profile
T5173 10782-10790 NN denotes Cytokine
T5420 12102-12103 DT denotes a
T5419 12093-12101 VB denotes mediated
T5418 12090-12092 NN denotes GP
T5417 12088-12089 -COMMA- denotes ,
T5416 12083-12088 NN denotes whole
T5415 12079-12082 DT denotes the
T5414 12076-12078 IN denotes On
T5413 12073-12074 -RRB- denotes )
T5412 12069-12073 CD denotes 0.01
T5411 12067-12068 SYM denotes =
T5410 12065-12066 NN denotes p
T5409 12060-12064 CC denotes both
T5408 12058-12059 -COLON- denotes ;
T5407 12057-12058 CD denotes 6
T5406 12055-12056 JJ denotes =
T5405 12053-12054 NN denotes n
T5404 12052-12053 -LRB- denotes (
T5403 12046-12051 NN denotes calc.
T5402 12036-12045 NN denotes GP/TSST-1
T5401 12033-12035 IN denotes of
T5400 12027-12032 NN denotes value
T5399 12015-12026 JJ denotes theoretical
T5398 12011-12014 DT denotes the
T5397 12008-12010 CC denotes or
T5396 12001-12007 NN denotes TSST-1
T5395 11998-12000 TO denotes to
T5394 11989-11997 VB denotes compared
T5393 11984-11988 WRB denotes when
T5392 11982-11983 NN denotes %
T5391 11980-11982 CD denotes 40
T5390 11974-11979 RB denotes about
T5389 11971-11973 IN denotes by
T5388 11964-11970 JJ denotes latter
T5387 11960-11963 DT denotes the
T5386 11956-11959 IN denotes for
T5385 11954-11955 -COMMA- denotes ,
T5384 11953-11954 NN denotes h
T5383 11950-11952 CD denotes 24
T5382 11948-11949 IN denotes –
T5381 11946-11947 NN denotes h
T5380 11943-11945 CD denotes 18
T1296 2318-2327 JJ denotes microbial
T1297 2328-2332 NN denotes cell
T1298 2333-2338 NN denotes walls
T1299 2339-2341 CC denotes or
T1300 2342-2345 MD denotes can
T1301 2346-2348 VB denotes be
T1302 2349-2357 VB denotes secreted
T1303 2358-2362 IN denotes from
T1304 2363-2367 CC denotes both
T1305 2367-2368 -COMMA- denotes ,
T1306 2369-2383 JJ denotes non-pathogenic
T1307 2384-2387 CC denotes and
T1308 2388-2398 JJ denotes pathogenic
T1309 2399-2404 NN denotes fungi
T1310 2405-2409 JJ denotes such
T1311 2410-2412 IN denotes as
T1312 2413-2415 NNP denotes S.
T1313 2416-2425 NNP denotes cerevisae
T1314 2426-2429 CC denotes and
T1315 2430-2432 NNP denotes C.
T1316 2433-2441 NNP denotes albicans
T1317 2442-2443 -LRB- denotes [
T1318 2443-2444 CD denotes 1
T1319 2444-2445 -RRB- denotes ]
T1320 2447-2452 DT denotes These
T1321 2453-2467 JJ denotes β-1→3-D-linked
T1322 2468-2475 NN denotes glucose
T1323 2476-2484 NN denotes polymers
T1324 2485-2488 VB denotes are
T1325 2489-2502 VB denotes characterized
T1326 2503-2505 IN denotes as
T1327 2506-2507 DT denotes a
T1328 2508-2514 JJ denotes fungal
T1329 2515-2534 JJ denotes pathogen-associated
T1330 2535-2544 JJ denotes molecular
T1331 2545-2552 NN denotes pattern
T1332 2553-2554 -LRB- denotes (
T1333 2554-2558 NN denotes PAMP
T1334 2558-2559 -RRB- denotes )
T1335 2560-2561 -LRB- denotes [
T1336 2561-2562 CD denotes 2
T1337 2562-2563 -RRB- denotes ]
T1338 2565-2568 DT denotes The
T1339 2569-2576 JJ denotes primary
T1340 2577-2585 JJ denotes cellular
T1341 2586-2597 NN denotes recognition
T1342 2598-2600 IN denotes of
T1343 2601-2616 NN denotes β-1→3-D-glucans
T1344 2617-2619 VB denotes is
T1345 2620-2628 VB denotes mediated
T1346 2629-2631 IN denotes by
T1347 2632-2639 JJ denotes several
T1348 2640-2654 JJ denotes β-1→3-D-glucan
T1349 2655-2664 NN denotes receptors
T1350 2665-2667 IN denotes on
T1351 2668-2678 NN denotes phagocytes
T1352 2679-2680 -LRB- denotes [
T1353 2680-2683 CD denotes 3,4
T1354 2683-2684 -RRB- denotes ]
T1355 2685-2688 CC denotes and
T1356 2689-2694 JJ denotes other
T1357 2695-2700 NN denotes cells
T1358 2701-2702 -LRB- denotes [
T1359 2702-2705 CD denotes 5,6
T1360 2705-2706 -RRB- denotes ]
T1361 2708-2713 JJ denotes Human
T1362 2714-2716 RB denotes as
T1363 2717-2721 RB denotes well
T1364 2722-2724 IN denotes as
T1365 2725-2731 JJ denotes murine
T1366 2732-2740 NN denotes Dectin-1
T1367 2741-2744 VB denotes has
T1368 2745-2749 VB denotes been
T1369 2750-2762 VB denotes demonstrated
T1370 2763-2765 TO denotes to
T1371 2766-2768 VB denotes be
T1372 2769-2772 DT denotes the
T1373 2773-2778 JJ denotes major
T1374 2779-2786 NN denotes pattern
T1375 2787-2798 NN denotes recognition
T1376 2799-2807 NN denotes receptor
T1377 2808-2809 -LRB- denotes (
T1378 2809-2812 NN denotes PRR
T1379 2812-2813 -RRB- denotes )
T1380 2814-2817 IN denotes for
T1381 2818-2824 JJ denotes intact
T1382 2825-2830 NN denotes yeast
T1383 2831-2834 CC denotes and
T1384 2835-2860 JJ denotes β-1→3-D-glucan-containing
T1385 2861-2870 NN denotes particles
T1386 2871-2872 -LRB- denotes (
T1387 2872-2876 FW denotes i.e.
T1388 2877-2884 NN denotes zymosan
T1389 2884-2885 -RRB- denotes )
T1390 2886-2888 IN denotes on
T1391 2889-2910 NN denotes monocytes/macrophages
T1392 2911-2913 RB denotes as
T1393 2914-2918 RB denotes well
T1394 2919-2921 IN denotes as
T1395 2922-2933 NN denotes neutrophils
T1396 2934-2937 CC denotes and
T1397 2938-2940 IN denotes on
T1398 2941-2948 JJ denotes primary
T1399 2949-2954 NN denotes cells
T1400 2955-2956 -LRB- denotes [
T1401 2956-2960 CD denotes 7-11
T1402 2960-2961 -RRB- denotes ]
T1403 2963-2965 IN denotes In
T1404 2966-2969 DT denotes the
T1405 2970-2976 JJ denotes murine
T1406 2977-2983 NN denotes system
T1407 2983-2984 -COMMA- denotes ,
T1408 2985-2992 NN denotes binding
T1409 2993-2995 IN denotes of
T1410 2996-3003 NN denotes zymosan
T1411 3004-3006 TO denotes to
T1412 3007-3015 NN denotes Dectin-1
T1413 3016-3024 VB denotes resulted
T1414 3025-3027 IN denotes in
T1415 3028-3038 NN denotes production
T1416 3039-3041 IN denotes of
T1417 3042-3046 NN denotes TNFα
T1418 3047-3054 IN denotes through
T1419 3055-3064 JJ denotes Toll-like
T1420 3065-3073 NN denotes receptor
T1421 3074-3075 CD denotes 2
T1422 3076-3079 CC denotes and
T1423 3080-3083 DT denotes the
T1424 3084-3091 NN denotes adaptor
T1425 3092-3099 NN denotes protein
T1426 3100-3105 NN denotes MyD88
T1427 3106-3107 -LRB- denotes [
T1428 3107-3109 CD denotes 12
T1429 3109-3110 -RRB- denotes ]
T1430 3112-3119 DT denotes Another
T1431 3120-3133 JJ denotes water-soluble
T1432 3134-3148 NN denotes β-1→3-D-glucan
T1433 3149-3150 -LRB- denotes (
T1434 3150-3160 NN denotes PGG-glucan
T1435 3160-3161 -RRB- denotes )
T1436 3162-3165 VB denotes has
T1437 3166-3170 VB denotes been
T1438 3171-3180 VB denotes described
T1439 3181-3183 TO denotes to
T1440 3184-3192 VB denotes activate
T1441 3193-3197 NN denotes NFκB
T1442 3198-3201 CC denotes and
T1443 3202-3208 NN denotes NFIL-6
T1444 3209-3211 IN denotes in
T1445 3212-3218 JJ denotes murine
T1446 3219-3223 NN denotes cell
T1447 3224-3229 NN denotes lines
T1448 3230-3231 -LRB- denotes [
T1449 3231-3236 CD denotes 13,14
T1450 3236-3237 -RRB- denotes ]
T1451 3239-3248 RB denotes Similarly
T1452 3248-3249 -COMMA- denotes ,
T1453 3250-3252 PRP denotes it
T1454 3253-3256 VB denotes has
T1455 3257-3261 VB denotes been
T1456 3262-3267 VB denotes shown
T1457 3268-3272 IN denotes that
T1458 3273-3288 NN denotes β-1→3-D-glucans
T1459 3289-3297 VB denotes activate
T1460 3298-3302 NN denotes NFκB
T1461 3303-3305 IN denotes in
T1462 3306-3307 DT denotes a
T1463 3308-3313 JJ denotes human
T1464 3314-3327 JJ denotes monocyte-like
T1465 3328-3332 NN denotes cell
T1466 3333-3337 NN denotes line
T1467 3338-3339 -LRB- denotes [
T1468 3339-3341 CD denotes 15
T1469 3341-3342 -RRB- denotes ]
T1470 3343-3346 CC denotes and
T1471 3347-3349 IN denotes in
T1472 3350-3355 JJ denotes human
T1473 3356-3373 JJ denotes polymorphonuclear
T1474 3374-3385 NN denotes neutrophils
T1475 3386-3387 -LRB- denotes (
T1476 3387-3390 NN denotes PMN
T1477 3390-3391 -RRB- denotes )
T1478 3391-3392 -COMMA- denotes ,
T1479 3393-3395 IN denotes in
T1480 3396-3399 DT denotes the
T1481 3400-3406 JJ denotes latter
T1482 3407-3411 NN denotes case
T1483 3412-3419 IN denotes without
T1484 3420-3429 NN denotes secretion
T1485 3430-3432 IN denotes of
T1486 3433-3449 JJ denotes pro-inflammatory
T1487 3450-3459 NN denotes cytokines
T1488 3460-3461 -LRB- denotes (
T1489 3461-3465 NN denotes IL-1
T1490 3465-3466 -COMMA- denotes ,
T1491 3467-3471 NN denotes IL-6
T1492 3471-3472 -COMMA- denotes ,
T1493 3473-3477 NN denotes TNFα
T1494 3477-3478 -RRB- denotes )
T1495 3479-3480 -LRB- denotes [
T1496 3480-3482 CD denotes 16
T1497 3482-3483 -RRB- denotes ]
T1498 3485-3488 CD denotes One
T1499 3489-3494 NN denotes study
T1500 3495-3503 VB denotes proposed
T1501 3504-3508 IN denotes that
T1502 3509-3512 DT denotes the
T1503 3513-3523 NN denotes production
T1504 3524-3526 IN denotes of
T1505 3527-3530 DT denotes the
T1506 3531-3548 JJ denotes anti-inflammatory
T1507 3549-3555 NN denotes IL-1RA
T1508 3555-3556 -COMMA- denotes ,
T1509 3557-3560 CC denotes but
T1510 3561-3564 RB denotes not
T1511 3565-3569 NN denotes IL-1
T1512 3570-3572 IN denotes by
T1513 3573-3578 JJ denotes human
T1514 3579-3588 NN denotes monocytes
T1515 3589-3592 MD denotes may
T1516 3593-3595 VB denotes be
T1517 3596-3597 DT denotes a
T1518 3598-3609 RB denotes potentially
T1519 3610-3620 JJ denotes protective
T1520 3621-3630 NN denotes mechanism
T1521 3631-3638 VB denotes induced
T1522 3639-3641 IN denotes by
T1523 3642-3656 NN denotes β-1→3-D-glucan
T1524 3657-3658 -LRB- denotes [
T1525 3658-3660 CD denotes 17
T1526 3660-3661 -RRB- denotes ]
T1527 3663-3668 CD denotes Three
T1528 3669-3674 JJ denotes other
T1529 3675-3689 NN denotes investigations
T1530 3690-3694 VB denotes have
T1531 3695-3703 VB denotes reported
T1532 3704-3708 IN denotes that
T1533 3709-3714 JJ denotes human
T1534 3715-3725 NN denotes leukocytes
T1535 3726-3729 CC denotes and
T1536 3730-3735 JJ denotes human
T1537 3736-3744 JJ denotes vascular
T1538 3745-3756 JJ denotes endothelial
T1539 3757-3762 NN denotes cells
T1540 3763-3770 VB denotes produce
T1541 3771-3775 NN denotes IL-8
T1542 3776-3778 IN denotes in
T1543 3779-3787 NN denotes response
T1544 3788-3790 TO denotes to
T1545 3791-3798 VB denotes zymosan
T1546 3799-3800 -LRB- denotes [
T1547 3800-3802 CD denotes 18
T1548 3802-3803 -RRB- denotes ]
T1549 3804-3806 CC denotes or
T1550 3807-3808 DT denotes a
T1551 3809-3822 JJ denotes water-soluble
T1552 3823-3837 NN denotes β-1→3-D-glucan
T1553 3838-3839 -LRB- denotes [
T1554 3839-3843 CD denotes 6,19
T1555 3843-3844 -RRB- denotes ]
T1556 3846-3848 IN denotes In
T1557 3849-3857 NN denotes addition
T1558 3857-3858 -COMMA- denotes ,
T1559 3859-3874 NN denotes β-1→3-D-glucans
T1560 3875-3879 VB denotes seem
T1561 3880-3882 TO denotes to
T1562 3883-3885 VB denotes be
T1563 3886-3890 JJ denotes able
T1564 3891-3893 TO denotes to
T1565 3894-3900 VB denotes modify
T1566 3901-3904 DT denotes the
T1567 3905-3913 NN denotes response
T1568 3914-3916 TO denotes to
T1569 3917-3933 JJ denotes pro-inflammatory
T1570 3934-3941 NN denotes stimuli
T1571 3942-3944 CC denotes or
T1572 3945-3949 RB denotes even
T1573 3950-3956 NN denotes sepsis
T1574 3958-3960 IN denotes In
T1575 3961-3962 DT denotes a
T1576 3963-3969 JJ denotes murine
T1577 3970-3983 JJ denotes polymicrobial
T1578 3984-3990 NN denotes sepsis
T1579 3991-3996 NN denotes model
T1580 3996-3997 -COMMA- denotes ,
T1581 3998-4012 NN denotes β-1→3-D-glucan
T1582 4013-4014 -LRB- denotes [
T1583 4014-4016 CD denotes 20
T1584 4016-4017 -RRB- denotes ]
T1585 4018-4027 NN denotes treatment
T1586 4028-4036 VB denotes resulted
T1587 4037-4039 IN denotes in
T1588 4040-4049 VB denotes decreased
T1589 4050-4056 JJ denotes septic
T1590 4057-4066 NN denotes morbidity
T1591 4067-4070 CC denotes and
T1592 4071-4080 NN denotes mortality
T1593 4081-4089 VB denotes mediated
T1594 4090-4093 IN denotes via
T1595 4094-4104 NN denotes inhibition
T1596 4105-4107 IN denotes of
T1597 4108-4112 NN denotes NFκB
T1598 4113-4116 CC denotes and
T1599 4117-4128 NN denotes stimulation
T1600 4129-4131 IN denotes of
T1601 4132-4135 DT denotes the
T1602 4136-4161 NN denotes phosphoinositide-3-kinase
T1603 4162-4163 -LRB- denotes (
T1604 4163-4167 NN denotes PI3K
T1605 4167-4168 -RRB- denotes )
T1606 4169-4176 NN denotes pathway
T1607 4177-4178 -LRB- denotes [
T1608 4178-4183 CD denotes 21,22
T1609 4183-4184 -RRB- denotes ]
T1610 4186-4191 DT denotes These
T1611 4192-4195 CC denotes and
T1612 4196-4201 JJ denotes other
T1613 4202-4208 NN denotes animal
T1614 4209-4216 NN denotes studies
T1615 4217-4218 -LRB- denotes [
T1616 4218-4223 CD denotes 23,24
T1617 4223-4224 -RRB- denotes ]
T1618 4225-4227 RB denotes as
T1619 4228-4232 RB denotes well
T1620 4233-4235 IN denotes as
T1621 4236-4237 DT denotes a
T1622 4238-4246 JJ denotes clinical
T1623 4247-4252 NN denotes trial
T1624 4253-4254 -LRB- denotes [
T1625 4254-4256 CD denotes 25
T1626 4256-4257 -RRB- denotes ]
T1627 4258-4265 VB denotes support
T1628 4266-4267 DT denotes a
T1629 4268-4278 JJ denotes protective
T1630 4279-4283 NN denotes role
T1631 4284-4286 IN denotes of
T1632 4287-4301 NN denotes β-1→3-D-glucan
T1633 4302-4304 IN denotes in
T1634 4305-4312 JJ denotes certain
T1635 4313-4329 JJ denotes pro-inflammatory
T1636 4330-4340 NN denotes conditions
T1637 4342-4345 DT denotes The
T1638 4346-4356 NN denotes mechanisms
T1639 4357-4367 VB denotes underlying
T1640 4368-4373 DT denotes these
T1641 4374-4384 JJ denotes beneficial
T1642 4385-4392 NN denotes effects
T1643 4393-4395 IN denotes of
T1644 4396-4410 NN denotes β-1→3-D-glucan
T1645 4411-4414 VB denotes are
T1646 4415-4419 RB denotes only
T1647 4420-4429 RB denotes partially
T1648 4430-4438 VB denotes resolved
T1649 4438-4439 -COMMA- denotes ,
T1650 4440-4450 RB denotes especially
T1651 4451-4453 IN denotes in
T1652 4454-4460 NN denotes humans
T1653 4462-4466 RB denotes Thus
T1654 4466-4467 -COMMA- denotes ,
T1655 4468-4471 DT denotes the
T1656 4472-4475 NN denotes aim
T1657 4476-4478 IN denotes of
T1658 4479-4483 DT denotes this
T1659 4484-4489 NN denotes study
T1660 4490-4493 VB denotes was
T1661 4494-4496 TO denotes to
T1662 4497-4506 VB denotes elucidate
T1663 4507-4516 JJ denotes molecular
T1664 4517-4520 CC denotes and
T1665 4521-4529 JJ denotes cellular
T1666 4530-4540 NN denotes mechanisms
T1667 4541-4543 IN denotes of
T1668 4544-4559 NN denotes β-1→3-D-glucans
T1669 4560-4562 IN denotes on
T1670 4563-4568 JJ denotes human
T1671 4569-4579 NN denotes leukocytes
T1672 4580-4582 IN denotes in
T1673 4583-4599 JJ denotes pro-inflammatory
T1674 4600-4610 NN denotes conditions
T1675 4611-4615 IN denotes with
T1676 4616-4623 JJ denotes special
T1677 4624-4632 NN denotes emphasis
T1678 4633-4635 IN denotes on
T1679 4636-4639 DT denotes the
T1680 4640-4648 NN denotes cytokine
T1681 4649-4656 NN denotes profile
T1682 4657-4660 CC denotes and
T1683 4661-4664 PRP-DOLLAR- denotes its
T1684 4665-4680 JJ denotes transcriptional
T1685 4681-4691 NN denotes regulation
T1686 4693-4696 IN denotes For
T1687 4697-4701 DT denotes this
T1688 4702-4709 NN denotes purpose
T1689 4709-4710 -COMMA- denotes ,
T1690 4711-4721 JJ denotes peripheral
T1691 4722-4727 NN denotes blood
T1692 4728-4739 JJ denotes mononuclear
T1693 4740-4745 NN denotes cells
T1694 4746-4747 -LRB- denotes (
T1695 4747-4751 NN denotes PBMC
T1696 4751-4752 -RRB- denotes )
T1697 4753-4757 VB denotes were
T1698 4758-4765 VB denotes exposed
T1699 4766-4768 TO denotes to
T1700 4769-4770 DT denotes a
T1701 4771-4783 JJ denotes well-defined
T1702 4784-4798 NN denotes β-1→3-D-glucan
T1703 4798-4799 -COMMA- denotes ,
T1704 4800-4804 FW denotes i.e.
T1705 4805-4811 NN denotes glucan
T1706 4812-4821 NN denotes phosphate
T1707 4822-4823 -LRB- denotes (
T1708 4823-4825 NN denotes GP
T1709 4825-4826 -RRB- denotes )
T1710 4827-4828 -LRB- denotes [
T1711 4828-4833 CD denotes 20,26
T1712 4833-4834 -RRB- denotes ]
T1713 4834-4835 -COMMA- denotes ,
T1714 4836-4841 RB denotes alone
T1715 4842-4844 CC denotes or
T1716 4845-4859 RB denotes simultaneously
T1717 4860-4864 IN denotes with
T1718 4865-4868 NN denotes LPS
T1719 4869-4873 IN denotes from
T1720 4874-4887 JJ denotes gram-negative
T1721 4888-4896 NN denotes bacteria
T1722 4897-4899 CC denotes or
T1723 4900-4903 DT denotes the
T1724 4904-4916 NN denotes superantigen
T1725 4917-4923 NN denotes TSST-1
T1726 4924-4928 IN denotes from
T1727 4929-4942 JJ denotes gram-positive
T1728 4943-4951 NN denotes bacteria
T1729 4952-4956 IN denotes over
T1730 4957-4959 CD denotes 48
T1731 4960-4961 NN denotes h
T1732 4963-4970 IN denotes Because
T1733 4971-4973 IN denotes of
T1734 4974-4977 DT denotes the
T1735 4978-4987 JJ denotes potential
T1736 4988-4994 NN denotes effect
T1737 4995-4997 IN denotes of
T1738 4998-5012 NN denotes β-1→3-D-glucan
T1739 5013-5015 IN denotes on
T1740 5016-5024 NN denotes cytokine
T1741 5025-5035 NN denotes production
T1742 5036-5037 -LRB- denotes [
T1743 5037-5045 CD denotes 12,16-19
T1744 5045-5046 -RRB- denotes ]
T1745 5046-5047 -COMMA- denotes ,
T1746 5048-5052 NN denotes TNFα
T1747 5052-5053 -COMMA- denotes ,
T1748 5054-5059 NN denotes IL-1β
T1749 5059-5060 -COMMA- denotes ,
T1750 5061-5065 NN denotes IL-6
T1751 5065-5066 -COMMA- denotes ,
T1752 5067-5071 NN denotes IL-8
T1753 5072-5075 CC denotes and
T1754 5076-5082 NN denotes IL-1RA
T1755 5083-5087 VB denotes were
T1756 5088-5096 VB denotes measured
T1757 5097-5099 RB denotes as
T1758 5100-5104 RB denotes well
T1759 5105-5107 IN denotes as
T1760 5108-5112 NN denotes IFNγ
T1761 5112-5113 -COMMA- denotes ,
T1762 5114-5118 NN denotes IL-2
T1763 5118-5119 -COMMA- denotes ,
T1764 5120-5124 NN denotes IL-4
T1765 5124-5125 -COMMA- denotes ,
T1766 5126-5131 NN denotes IL-10
T1767 5131-5132 -COMMA- denotes ,
T1768 5133-5138 NN denotes IL-12
T1769 5139-5142 CC denotes and
T1770 5143-5148 NN denotes TGFβ1
T1771 5150-5165 RB denotes Correspondingly
T1772 5165-5166 -COMMA- denotes ,
T1773 5167-5171 CD denotes four
T1774 5172-5176 NN denotes NFκB
T1775 5177-5182 NN denotes sites
T1776 5183-5187 IN denotes from
T1777 5188-5191 DT denotes the
T1778 5192-5196 NN denotes TNFα
T1779 5197-5205 NN denotes promoter
T1780 5206-5207 -LRB- denotes (
T1781 5207-5208 NN denotes κ
T1782 5209-5218 NN denotes consensus
T1783 5218-5219 -COMMA- denotes ,
T1784 5220-5222 NN denotes κ1
T1785 5222-5223 -COMMA- denotes ,
T1786 5224-5226 NN denotes κ2
T1787 5226-5227 -COMMA- denotes ,
T1788 5228-5230 CD denotes κ3
T1789 5230-5231 -RRB- denotes )
T1790 5232-5233 -LRB- denotes [
T1791 5233-5235 CD denotes 27
T1792 5235-5236 -RRB- denotes ]
T1793 5236-5237 -COMMA- denotes ,
T1794 5238-5239 DT denotes a
T1795 5240-5241 JJ denotes κ
T1796 5242-5251 NN denotes consensus
T1797 5252-5256 NN denotes site
T1798 5257-5261 IN denotes from
T1799 5262-5265 DT denotes the
T1800 5266-5270 NN denotes IL-8
T1801 5271-5279 NN denotes promoter
T1802 5280-5281 -LRB- denotes [
T1803 5281-5283 CD denotes 28
T1804 5283-5284 -RRB- denotes ]
T1805 5284-5285 -COMMA- denotes ,
T1806 5286-5288 DT denotes an
T1807 5289-5293 NN denotes NFAT
T1808 5294-5298 NN denotes site
T1809 5299-5303 IN denotes from
T1810 5304-5307 DT denotes the
T1811 5308-5312 NN denotes IFNγ
T1812 5313-5321 NN denotes promoter
T1813 5322-5323 -LRB- denotes (
T1814 5323-5327 NN denotes ATP2
T1815 5327-5328 -RRB- denotes )
T1816 5329-5330 -LRB- denotes [
T1817 5330-5332 CD denotes 29
T1818 5332-5333 -RRB- denotes ]
T1819 5334-5337 CC denotes and
T1820 5338-5339 DT denotes a
T1821 5340-5349 NN denotes consensus
T1822 5350-5356 NN denotes NFIL-6
T1823 5357-5361 NN denotes site
T1824 5362-5366 IN denotes from
T1825 5367-5370 DT denotes the
T1826 5371-5375 NN denotes IL-6
T1827 5376-5384 NN denotes promoter
T1828 5385-5386 -LRB- denotes [
T1829 5386-5388 CD denotes 13
T1830 5388-5389 -RRB- denotes ]
T1831 5390-5394 VB denotes were
T1832 5395-5403 VB denotes examined
T1833 5405-5412 IN denotes Because
T1834 5413-5415 IN denotes of
T1835 5416-5419 DT denotes the
T1836 5420-5437 JJ denotes anti-inflammatory
T1837 5438-5442 NN denotes role
T1838 5443-5445 IN denotes of
T1839 5446-5452 NN denotes IL-1RA
T1840 5452-5453 -COMMA- denotes ,
T1841 5454-5456 PRP denotes we
T1842 5457-5464 VB denotes focused
T1843 5465-5467 IN denotes on
T1844 5468-5475 NN denotes binding
T1845 5476-5478 IN denotes of
T1846 5479-5492 NN denotes transcription
T1847 5493-5500 NN denotes factors
T1848 5501-5503 TO denotes to
T1849 5504-5507 DT denotes the
T1850 5508-5514 NN denotes IL-1RA
T1851 5515-5523 NN denotes promoter
T1852 5525-5527 DT denotes An
T1853 5528-5538 JJ denotes inhibitory
T1854 5539-5546 NN denotes element
T1855 5547-5550 CC denotes and
T1856 5551-5556 CD denotes three
T1857 5557-5572 JJ denotes positive-acting
T1858 5573-5585 JJ denotes LPS-response
T1859 5586-5594 NN denotes elements
T1860 5595-5596 -LRB- denotes (
T1861 5596-5601 NN denotes LRE-1
T1862 5601-5602 -COMMA- denotes ,
T1863 5603-5608 NN denotes LRE-2
T1864 5609-5612 CC denotes and
T1865 5613-5618 NN denotes LRE-3
T1866 5618-5619 -RRB- denotes )
T1867 5620-5622 IN denotes in
T1868 5623-5626 DT denotes the
T1869 5627-5633 NN denotes IL-1RA
T1870 5634-5642 NN denotes promoter
T1871 5642-5643 -COMMA- denotes ,
T1872 5644-5653 VB denotes including
T1873 5654-5658 NN denotes NFκB
T1874 5658-5659 -COMMA- denotes ,
T1875 5660-5664 NN denotes PU.1
T1876 5665-5668 CC denotes and
T1877 5669-5675 NN denotes NFIL-6
T1878 5676-5681 NN denotes sites
T1879 5681-5682 -COMMA- denotes ,
T1880 5683-5687 VB denotes have
T1881 5688-5692 VB denotes been
T1882 5693-5706 VB denotes characterized
T1883 5707-5717 RB denotes previously
T1884 5718-5719 -LRB- denotes [
T1885 5719-5724 CD denotes 30-33
T1886 5724-5725 -RRB- denotes ]
T1887 5727-5732 VB denotes Using
T1888 5733-5746 JJ denotes computational
T1889 5747-5755 NN denotes analysis
T1890 5756-5759 IN denotes for
T1891 5760-5768 NN denotes homology
T1892 5769-5775 NN denotes search
T1893 5776-5777 -LRB- denotes [
T1894 5777-5779 CD denotes 34
T1895 5779-5780 -RRB- denotes ]
T1896 5780-5781 -COMMA- denotes ,
T1897 5782-5784 PRP denotes we
T1898 5785-5791 VB denotes looked
T1899 5792-5795 IN denotes for
T1900 5796-5799 JJ denotes new
T1901 5800-5807 NN denotes binding
T1902 5808-5814 NN denotes motifs
T1903 5815-5817 IN denotes in
T1904 5818-5821 DT denotes the
T1905 5822-5828 NN denotes IL-1RA
T1906 5829-5837 NN denotes promoter
T3336 5849-5856 NN denotes Binding
T3337 5857-5867 NN denotes activities
T3338 5868-5870 IN denotes of
T3339 5871-5875 NN denotes NFκB
T3340 5875-5876 -COMMA- denotes ,
T3341 5877-5883 NN denotes NFIL-6
T3342 5884-5887 CC denotes and
T3343 5888-5892 NN denotes NFAT
T3344 5893-5897 IN denotes from
T3345 5898-5903 JJ denotes human
T3346 5904-5908 NN denotes PBMC
T3347 5909-5911 TO denotes to
T3348 5912-5915 DT denotes the
T3349 5916-5920 NN denotes TNFα
T3350 5920-5921 -COMMA- denotes ,
T3351 5922-5926 NN denotes IL-6
T3352 5927-5930 CC denotes and
T3353 5931-5935 NN denotes IFNγ
T3354 5936-5945 NN denotes promoters
T3355 5946-5955 VB denotes following
T3356 5956-5958 DT denotes an
T3357 5959-5961 FW denotes in
T3358 5962-5967 FW denotes vitro
T3359 5968-5979 NN denotes stimulation
T3360 5980-5981 -LRB- denotes (
T3361 5981-5982 CD denotes 1
T3362 5983-5984 NN denotes h
T3363 5984-5985 -RRB- denotes )
T3364 5986-5990 IN denotes with
T3365 5991-5994 NN denotes LPS
T3366 5994-5995 -COMMA- denotes ,
T3367 5996-6002 NN denotes TSST-1
T3368 6002-6003 -COMMA- denotes ,
T3369 6004-6006 NN denotes GP
T3370 6006-6007 -COMMA- denotes ,
T3371 6008-6010 NN denotes GP
T3372 6011-6012 SYM denotes +
T3373 6013-6016 NN denotes LPS
T3374 6017-6020 CC denotes and
T3375 6021-6023 NN denotes GP
T3376 6024-6025 SYM denotes +
T3377 6026-6032 NN denotes TSST-1
T3378 6033-6035 NN denotes GP
T3379 6036-6043 VB denotes induced
T3380 6044-6048 NN denotes band
T3381 6049-6055 NN denotes shifts
T3382 6055-6056 -COMMA- denotes ,
T3383 6057-6067 VB denotes indicating
T3384 6068-6075 NN denotes binding
T3385 6076-6078 IN denotes of
T3386 6079-6083 NN denotes NFκB
T3387 6084-6086 RB denotes as
T3388 6087-6091 RB denotes well
T3389 6092-6094 IN denotes as
T3390 6095-6097 IN denotes of
T3391 6098-6104 NN denotes NFIL-6
T3392 6105-6107 TO denotes to
T3393 6108-6111 DT denotes the
T3394 6112-6125 VB denotes corresponding
T3395 6126-6129 NN denotes DNA
T3396 6130-6146 NN denotes oligonucleotides
T3397 6147-6148 -LRB- denotes (
T3398 6148-6149 NN denotes κ
T3399 6150-6159 NN denotes consensus
T3400 6159-6160 -COMMA- denotes ,
T3401 6161-6163 NN denotes κ1
T3402 6163-6164 -COMMA- denotes ,
T3403 6165-6167 NN denotes κ2
T3404 6167-6168 -COMMA- denotes ,
T3405 6169-6171 CD denotes κ3
T3406 6172-6177 NN denotes sites
T3407 6178-6182 IN denotes from
T3408 6183-6186 DT denotes the
T3409 6187-6191 NN denotes TNFα
T3410 6192-6200 NN denotes promoter
T3411 6200-6201 -COLON- denotes ;
T3412 6202-6203 LS denotes κ
T3413 6204-6213 NN denotes consensus
T3414 6214-6218 IN denotes from
T3415 6219-6222 DT denotes the
T3416 6223-6227 NN denotes IL-8
T3417 6228-6236 NN denotes promoter
T3418 6236-6237 -COLON- denotes ;
T3419 6238-6253 NN denotes NFIL-6consensus
T3420 6254-6258 IN denotes from
T3421 6259-6262 DT denotes the
T3422 6263-6267 NN denotes IL-6
T3423 6268-6276 NN denotes promoter
T3424 6276-6277 -COLON- denotes ;
T3425 6278-6283 NNP denotes Table
T3426 6284-6285 CD denotes 1
T3427 6285-6286 -COLON- denotes ;
T3428 6287-6291 NNP denotes Fig.
T3429 6292-6294 NN denotes 1A
T3430 6294-6295 -RRB- denotes )
T3431 6297-6300 DT denotes The
T3432 6301-6307 NN denotes extent
T3433 6308-6310 IN denotes of
T3434 6311-6314 DT denotes the
T3435 6315-6319 NN denotes band
T3436 6320-6326 NN denotes shifts
T3437 6327-6334 VB denotes induced
T3438 6335-6337 IN denotes by
T3439 6338-6340 NN denotes GP
T3440 6341-6344 VB denotes was
T3441 6345-6348 RB denotes not
T3442 6349-6362 RB denotes statistically
T3443 6363-6372 JJ denotes different
T3444 6373-6377 WRB denotes when
T3445 6378-6386 VB denotes compared
T3446 6387-6389 TO denotes to
T3447 6390-6393 NN denotes LPS
T3448 6394-6396 CC denotes or
T3449 6397-6403 NN denotes TSST-1
T3450 6404-6405 -LRB- denotes (
T3451 6405-6409 NN denotes Fig.
T3452 6410-6412 NN denotes 1B
T3453 6412-6413 -RRB- denotes )
T3454 6415-6416 DT denotes A
T3455 6417-6427 NN denotes supershift
T3456 6427-6428 -COMMA- denotes ,
T3457 6429-6438 VB denotes conducted
T3458 6439-6442 IN denotes for
T3459 6443-6445 DT denotes an
T3460 6446-6450 NN denotes NFκB
T3461 6451-6460 NN denotes consensus
T3462 6461-6465 NN denotes site
T3463 6466-6470 IN denotes from
T3464 6471-6474 DT denotes the
T3465 6475-6479 NN denotes IL-8
T3466 6480-6488 NN denotes promoter
T3467 6488-6489 -COMMA- denotes ,
T3468 6490-6502 VB denotes demonstrated
T3469 6503-6504 DT denotes a
T3470 6505-6515 JJ denotes GP-induced
T3471 6516-6527 JJ denotes predominant
T3472 6528-6535 NN denotes binding
T3473 6536-6538 IN denotes of
T3474 6539-6543 NN denotes NFκB
T3475 6544-6547 NN denotes p65
T3476 6548-6551 CC denotes and
T3477 6552-6554 TO denotes to
T3478 6555-6556 DT denotes a
T3479 6557-6563 JJ denotes lesser
T3480 6564-6570 NN denotes degree
T3481 6571-6573 IN denotes of
T3482 6574-6577 NN denotes p50
T3483 6578-6579 -LRB- denotes (
T3484 6579-6583 NN denotes Fig.
T3485 6584-6586 NN denotes 1A
T3486 6586-6587 -RRB- denotes )
T3487 6589-6600 RB denotes Accordingly
T3488 6600-6601 -COMMA- denotes ,
T3489 6602-6604 DT denotes an
T3490 6605-6615 NN denotes immunoblot
T3491 6616-6618 IN denotes of
T3492 6619-6626 JJ denotes nuclear
T3493 6627-6635 NN denotes extracts
T3494 6636-6640 IN denotes from
T3495 6641-6651 JJ denotes GP-treated
T3496 6652-6656 NN denotes PBMC
T3497 6657-6663 VB denotes showed
T3498 6664-6665 DT denotes a
T3499 6666-6672 JJ denotes strong
T3500 6673-6680 NN denotes binding
T3501 6681-6683 IN denotes of
T3502 6684-6688 NN denotes NFκB
T3503 6689-6692 NN denotes p65
T3504 6693-6696 CC denotes and
T3505 6697-6698 DT denotes a
T3506 6699-6705 JJ denotes weaker
T3507 6706-6714 NN denotes reaction
T3508 6715-6717 IN denotes of
T3509 6718-6721 NN denotes p50
T3510 6721-6722 -COMMA- denotes ,
T3511 6723-6730 IN denotes whereas
T3512 6731-6734 NN denotes p52
T3513 6735-6738 VB denotes was
T3514 6739-6747 JJ denotes negative
T3515 6748-6749 -LRB- denotes (
T3516 6749-6753 NN denotes Fig.
T3517 6754-6755 CD denotes 2
T3518 6755-6756 -RRB- denotes )
T3519 6758-6770 JJ denotes Simultaneous
T3520 6771-6783 NN denotes co-treatment
T3521 6784-6786 IN denotes of
T3522 6787-6791 NN denotes PBMC
T3523 6792-6796 IN denotes with
T3524 6797-6799 NN denotes GP
T3525 6800-6803 VB denotes did
T3526 6804-6807 RB denotes not
T3527 6808-6814 VB denotes change
T3528 6815-6818 DT denotes the
T3529 6819-6830 JJ denotes LPS-induced
T3530 6831-6835 NN denotes NFκB
T3531 6836-6843 VB denotes binding
T3532 6844-6846 TO denotes to
T3533 6847-6853 NN denotes oligos
T3534 6854-6858 IN denotes from
T3535 6859-6862 DT denotes the
T3536 6863-6867 NN denotes TNFα
T3537 6868-6876 NN denotes promoter
T3538 6877-6890 RB denotes significantly
T3539 6891-6892 -LRB- denotes (
T3540 6892-6896 NNP denotes Fig.
T3541 6897-6899 NN denotes 1B
T3542 6899-6900 -RRB- denotes )
T3543 6900-6901 -COMMA- denotes ,
T3544 6902-6905 CC denotes but
T3545 6906-6919 RB denotes substantially
T3546 6920-6929 VB denotes decreased
T3547 6930-6933 DT denotes the
T3548 6934-6948 JJ denotes TSST-1-induced
T3549 6949-6953 NN denotes NFκB
T3550 6954-6961 NN denotes binding
T3551 6962-6966 WRB denotes when
T3552 6967-6975 VB denotes compared
T3553 6976-6978 TO denotes to
T3554 6979-6985 NN denotes TSST-1
T3555 6986-6988 CC denotes or
T3556 6989-6991 NN denotes GP
T3557 6992-6993 -LRB- denotes (
T3558 6993-6996 CD denotes 100
T3559 6997-6999 NN denotes μg
T3560 6999-7000 -RRB- denotes )
T3561 7001-7004 CC denotes and
T3562 7005-7009 RB denotes thus
T3563 7010-7018 VB denotes differed
T3564 7019-7029 RB denotes completely
T3565 7030-7034 IN denotes from
T3566 7035-7038 DT denotes the
T3567 7039-7050 JJ denotes theoretical
T3568 7051-7056 NN denotes value
T3569 7057-7059 IN denotes of
T3570 7060-7069 NN denotes GP/TSST-1
T3571 7070-7075 NN denotes calc.
T3572 7076-7077 -LRB- denotes (
T3573 7077-7078 NN denotes n
T3574 7079-7080 SYM denotes =
T3575 7081-7082 CD denotes 4
T3576 7082-7083 -COLON- denotes ;
T3577 7084-7085 NN denotes p
T3578 7086-7087 SYM denotes <
T3579 7088-7092 CD denotes 0.05
T3580 7093-7096 IN denotes vs.
T3581 7097-7106 NN denotes GP/TSST-1
T3582 7107-7112 NN denotes calc.
T3583 7113-7116 CC denotes and
T3584 7117-7118 NN denotes p
T3585 7119-7120 SYM denotes =
T3586 7121-7125 CD denotes 0.07
T3587 7126-7129 IN denotes vs.
T3588 7130-7136 NN denotes TSST-1
T3589 7136-7137 -COLON- denotes ;
T3590 7138-7142 FW denotes Fig.
T3591 7143-7145 NN denotes 1B
T3592 7145-7146 -RRB- denotes )
T3593 7148-7150 NN denotes GP
T3594 7151-7154 VB denotes was
T3595 7155-7159 RB denotes also
T3596 7160-7164 JJ denotes able
T3597 7165-7167 TO denotes to
T3598 7168-7174 VB denotes induce
T3599 7175-7179 NN denotes band
T3600 7180-7186 NN denotes shifts
T3601 7187-7197 JJ denotes indicative
T3602 7198-7200 IN denotes of
T3603 7201-7208 NN denotes binding
T3604 7209-7211 IN denotes of
T3605 7212-7222 JJ denotes particular
T3606 7223-7231 NN denotes variants
T3607 7232-7234 IN denotes of
T3608 7235-7239 NN denotes NFAT
T3609 7240-7242 TO denotes to
T3610 7243-7245 DT denotes an
T3611 7246-7251 NN denotes oligo
T3612 7252-7256 IN denotes from
T3613 7257-7260 DT denotes the
T3614 7261-7265 NN denotes IFNγ
T3615 7266-7274 NN denotes promoter
T3616 7275-7276 -LRB- denotes (
T3617 7276-7280 NN denotes Fig.
T3618 7281-7283 NN denotes 1A
T3619 7283-7284 -RRB- denotes )
T3620 7286-7288 DT denotes An
T3621 7289-7299 NN denotes immunoblot
T3622 7300-7303 IN denotes for
T3623 7304-7307 CD denotes two
T3624 7308-7312 NN denotes NFAT
T3625 7313-7321 NN denotes subunits
T3626 7322-7334 VB denotes demonstrated
T3627 7335-7336 DT denotes a
T3628 7337-7347 JJ denotes GP-induced
T3629 7348-7355 NN denotes binding
T3630 7356-7358 IN denotes of
T3631 7359-7365 NN denotes NFATc2
T3632 7366-7369 CC denotes and
T3633 7370-7372 TO denotes to
T3634 7373-7374 DT denotes a
T3635 7375-7381 JJ denotes lesser
T3636 7382-7388 NN denotes degree
T3637 7389-7391 IN denotes of
T3638 7392-7398 NN denotes NFATc1
T3639 7399-7400 -LRB- denotes (
T3640 7400-7404 NN denotes Fig.
T3641 7405-7406 CD denotes 2
T3642 7406-7407 -RRB- denotes )
T14241 32191-32192 -RRB- denotes ]
T18477 35706-35718 NN denotes instructions
T26164 7418-7423 NN denotes Sense
T26165 7424-7430 NN denotes strand
T26166 7431-7433 IN denotes of
T26167 7434-7450 NN denotes oligonucleotides
T26168 7451-7455 VB denotes used
T26169 7456-7458 IN denotes in
T26170 7459-7464 NN denotes EMSAs
T19306 37561-37564 DT denotes the
T19305 37559-37560 -COMMA- denotes ,
T19304 37558-37559 -RRB- denotes )
T19303 37551-37558 NNP denotes Germany
T19302 37549-37550 -COMMA- denotes ,
T19301 37538-37549 NNP denotes Deisenhofen
T19300 37536-37537 -COMMA- denotes ,
T19299 37531-37536 NNP denotes Fluka
T19298 37530-37531 -LRB- denotes (
T19297 37526-37529 NN denotes BSA
T19296 37524-37525 NN denotes %
T19295 37519-37524 NN denotes PBS/3
T19294 37514-37518 IN denotes with
T19293 37505-37513 VB denotes blocking
T19292 37499-37504 IN denotes After
T19291 37496-37497 -RRB- denotes )
T19290 37489-37496 NN denotes Bio-Rad
T19289 37488-37489 -LRB- denotes (
T19288 37479-37487 NN denotes membrane
T19287 37464-37478 NN denotes nitrocellulose
T19286 37462-37463 DT denotes a
T19285 37457-37461 IN denotes onto
T19284 37449-37456 VB denotes blotted
T19283 37444-37448 VB denotes were
T19282 37435-37443 NN denotes proteins
T19281 37427-37434 JJ denotes nuclear
T19280 37423-37426 DT denotes The
T19279 36610-36614 NN denotes blot
T19278 36608-36609 -RRB- denotes )
T19277 36605-36608 NN denotes Dot
T19276 36604-36605 -LRB- denotes (
T19275 36597-36603 NN denotes Immuno
T19318 37632-37636 CD denotes 2000
T19317 37631-37632 -COLON- denotes :
T19316 37630-37631 CD denotes 1
T19315 37622-37629 VB denotes diluted
T19314 37611-37621 NN denotes antibodies
T19313 37603-37610 JJ denotes primary
T19312 37599-37602 DT denotes the
T19311 37594-37598 IN denotes with
T19310 37584-37593 RB denotes overnight
T19309 37574-37583 VB denotes incubated
T19308 37570-37573 VB denotes was
T19307 37565-37569 NN denotes blot
T18303 34747-34763 NN denotes Oligonucleotides
T25071 21536-21537 -RRB- denotes )
T25070 21535-21536 CD denotes 3
T25069 21533-21534 SYM denotes =
T25068 21531-21532 NN denotes n
T25067 21530-21531 -LRB- denotes (
T25066 21526-21529 NN denotes SEM
T25065 21524-21525 NN denotes ±
T25064 21519-21523 JJ denotes mean
T25063 21516-21518 IN denotes as
T25062 21510-21515 VB denotes shown
T25061 21506-21509 VB denotes are
T25060 21501-21505 NN denotes Data
T25059 21498-21499 -RRB- denotes )
T25058 21494-21498 CD denotes 0.05
T25057 21492-21493 SYM denotes <
T25056 21490-21491 NN denotes p
T25055 21488-21489 SYM denotes =
T25054 21486-21487 SYM denotes *
T25053 21485-21486 -LRB- denotes (
T25052 21479-21484 NN denotes IL-1β
T25051 21476-21478 IN denotes of
T25050 21471-21475 IN denotes than
T25049 21464-21470 NN denotes IL-1RA
T25048 21461-21463 IN denotes of
T25047 21450-21460 NN denotes production
T25046 21443-21449 JJ denotes higher
T25045 21441-21442 DT denotes a
T25044 21436-21440 FW denotes i.e.
T25043 21434-21435 -COMMA- denotes ,
T25042 21433-21434 NN denotes h
T1289 2268-2283 NN denotes β-1→3-D-glucans
T1290 2284-2289 VB denotes occur
T1291 2290-2292 IN denotes as
T1292 2293-2294 DT denotes a
T1293 2295-2304 JJ denotes principal
T1294 2305-2314 NN denotes component
T1295 2315-2317 IN denotes of
T14173 31774-31779 WDT denotes which
T14172 31772-31773 -COMMA- denotes ,
T14171 31771-31772 -RRB- denotes ]
T14170 31769-31771 CD denotes 50
T14169 31768-31769 -LRB- denotes [
T14168 31763-31767 NN denotes PI3K
T14167 31759-31762 IN denotes via
T14166 31753-31758 NN denotes place
T14165 31748-31752 VB denotes take
T14164 31743-31747 RB denotes also
T14163 31739-31742 MD denotes can
T14162 31734-31738 NN denotes NFκB
T14161 31731-31733 IN denotes of
T14160 31720-31730 NN denotes Activation
T14159 31717-31718 -RRB- denotes ]
R437 T1308 T1307 arg2Of pathogenic,and
R438 T1309 T1303 arg2Of fungi,from
R439 T1309 T1305 arg1Of fungi,","
R440 T1309 T1306 arg1Of fungi,non-pathogenic
R441 T1309 T1308 arg1Of fungi,pathogenic
R442 T1309 T1311 arg1Of fungi,as
R443 T1311 T1310 arg1Of as,such
R444 T1313 T1312 arg1Of cerevisae,S.
R445 T1313 T1314 arg1Of cerevisae,and
R446 T1314 T1311 arg2Of and,as
R447 T1314 T1317 arg1Of and,[
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R449 T1316 T1315 arg1Of albicans,C.
R450 T1318 T1317 arg2Of 1,[
R451 T1319 T1317 arg3Of ],[
R452 T1323 T1320 arg1Of polymers,These
R453 T1323 T1321 arg1Of polymers,β-1→3-D-linked
R454 T1323 T1322 arg1Of polymers,glucose
R455 T1323 T1324 arg1Of polymers,are
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R457 T1325 T1324 arg2Of characterized,are
R458 T1325 T1326 arg1Of characterized,as
R459 T1325 T1335 arg1Of characterized,[
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R464 T1331 T1330 arg1Of pattern,molecular
R465 T1331 T1332 arg1Of pattern,(
R466 T1333 T1332 arg2Of PAMP,(
R467 T1334 T1332 arg3Of ),(
R468 T1336 T1335 arg2Of 2,[
R469 T1337 T1335 arg3Of ],[
R470 T1341 T1338 arg1Of recognition,The
R471 T1341 T1339 arg1Of recognition,primary
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R473 T1341 T1342 arg1Of recognition,of
R474 T1341 T1344 arg1Of recognition,is
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R477 T1345 T1344 arg2Of mediated,is
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R480 T1349 T1347 arg1Of receptors,several
R481 T1349 T1348 arg1Of receptors,β-1→3-D-glucan
R482 T1349 T1350 arg1Of receptors,on
R483 T1351 T1352 arg1Of phagocytes,[
R484 T1351 T1355 arg1Of phagocytes,and
R485 T1353 T1352 arg2Of "3,4",[
R486 T1354 T1352 arg3Of ],[
R487 T1355 T1350 arg2Of and,on
R488 T1357 T1355 arg2Of cells,and
R489 T1357 T1356 arg1Of cells,other
R490 T1357 T1358 arg1Of cells,[
R491 T1359 T1358 arg2Of "5,6",[
R492 T1360 T1358 arg3Of ],[
R493 T1361 T1364 arg1Of Human,as
R494 T1364 T1362 arg1Of as,as
R495 T1364 T1363 arg1Of as,well
R496 T1365 T1364 arg2Of murine,as
R497 T1366 T1361 arg1Of Dectin-1,Human
R498 T1366 T1365 arg1Of Dectin-1,murine
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R500 T1366 T1368 arg1Of Dectin-1,been
R501 T1366 T1369 arg2Of Dectin-1,demonstrated
R502 T1366 T1371 arg1Of Dectin-1,be
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R506 T1371 T1370 arg1Of be,to
R507 T1371 T1380 arg1Of be,for
R508 T1371 T1397 arg1Of be,on
R509 T1376 T1371 arg2Of receptor,be
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R512 T1376 T1374 arg1Of receptor,pattern
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R514 T1376 T1377 arg1Of receptor,(
R515 T1378 T1377 arg2Of PRR,(
R516 T1379 T1377 arg3Of ),(
R517 T1380 T1396 arg1Of for,and
R518 T1382 T1381 arg1Of yeast,intact
R519 T1382 T1383 arg1Of yeast,and
R520 T1383 T1380 arg2Of and,for
R521 T1383 T1390 arg1Of and,on
R522 T1385 T1383 arg2Of particles,and
R523 T1385 T1384 arg1Of particles,β-1→3-D-glucan-containing
R524 T1385 T1386 arg1Of particles,(
R525 T1387 T1386 arg2Of i.e.,(
R526 T1388 T1387 arg2Of zymosan,i.e.
R527 T1389 T1386 arg3Of ),(
R528 T1391 T1394 arg1Of monocytes/macrophages,as
R529 T1394 T1390 arg2Of as,on
R530 T1394 T1392 arg1Of as,as
R531 T1394 T1393 arg1Of as,well
R532 T1395 T1394 arg2Of neutrophils,as
R533 T1397 T1396 arg2Of on,and
R534 T1399 T1397 arg2Of cells,on
R535 T1399 T1398 arg1Of cells,primary
R536 T1399 T1400 arg1Of cells,[
R537 T1401 T1400 arg2Of 7-11,[
R538 T1402 T1400 arg3Of ],[
R539 T1406 T1403 arg2Of system,In
R540 T1406 T1404 arg1Of system,the
R541 T1406 T1405 arg1Of system,murine
R542 T1408 T1409 arg1Of binding,of
R543 T1408 T1411 arg1Of binding,to
R544 T1408 T1413 arg1Of binding,resulted
R545 T1410 T1409 arg2Of zymosan,of
R546 T1412 T1411 arg2Of Dectin-1,to
R547 T1413 T1403 arg1Of resulted,In
R548 T1413 T1407 arg1Of resulted,","
R549 T1413 T1414 arg1Of resulted,in
R550 T1413 T1418 arg1Of resulted,through
R551 T1413 T1427 arg1Of resulted,[
R552 T1415 T1414 arg2Of production,in
R553 T1415 T1416 arg1Of production,of
R554 T1417 T1416 arg2Of TNFα,of
R555 T1420 T1419 arg1Of receptor,Toll-like
R556 T1420 T1421 arg1Of receptor,2
R557 T1420 T1422 arg1Of receptor,and
R558 T1422 T1418 arg2Of and,through
R559 T1426 T1422 arg2Of MyD88,and
R560 T1426 T1423 arg1Of MyD88,the
R561 T1426 T1424 arg1Of MyD88,adaptor
R562 T1426 T1425 arg1Of MyD88,protein
R563 T1428 T1427 arg2Of 12,[
R564 T1429 T1427 arg3Of ],[
R565 T1432 T1430 arg1Of β-1→3-D-glucan,Another
R566 T1432 T1431 arg1Of β-1→3-D-glucan,water-soluble
R567 T1432 T1433 arg1Of β-1→3-D-glucan,(
R568 T1432 T1436 arg1Of β-1→3-D-glucan,has
R569 T1432 T1437 arg1Of β-1→3-D-glucan,been
R570 T1432 T1438 arg2Of β-1→3-D-glucan,described
R571 T1432 T1440 arg1Of β-1→3-D-glucan,activate
R572 T1434 T1433 arg2Of PGG-glucan,(
R573 T1435 T1433 arg3Of ),(
R574 T1438 T1436 arg2Of described,has
R575 T1438 T1437 arg2Of described,been
R576 T1440 T1438 arg3Of activate,described
R577 T1440 T1439 arg1Of activate,to
R578 T1440 T1444 arg1Of activate,in
R579 T1441 T1442 arg1Of NFκB,and
R580 T1442 T1440 arg2Of and,activate
R581 T1443 T1442 arg2Of NFIL-6,and
R582 T1447 T1444 arg2Of lines,in
R583 T1447 T1445 arg1Of lines,murine
R584 T1447 T1446 arg1Of lines,cell
R585 T1447 T1448 arg1Of lines,[
R586 T1449 T1448 arg2Of "13,14",[
R7949 T12792 T12791 arg1Of models,Animal
R7950 T12792 T12793 arg1Of models,of
R7951 T12792 T12798 arg1Of models,suggest
R7952 T12794 T12795 arg1Of sepsis,and
R7953 T12795 T12793 arg2Of and,of
R7954 T12797 T12795 arg2Of injury,and
R7955 T12797 T12796 arg1Of injury,myocardial
R7956 T12801 T12800 arg1Of β-1→3-D-glucan,a
R7957 T12801 T12802 arg1Of β-1→3-D-glucan,like
R7958 T12801 T12804 arg1Of β-1→3-D-glucan,mediates
R7959 T12803 T12802 arg2Of GP,like
R7960 T12804 T12798 arg2Of mediates,suggest
R7961 T12804 T12799 arg1Of mediates,that
R7962 T12804 T12808 arg1Of mediates,","
R7963 T12804 T12809 arg1Of mediates,in
R7964 T12804 T12811 arg1Of mediates,","
R7965 T12804 T12812 arg1Of mediates,via
R7966 T12804 T12820 arg1Of mediates,[
R7967 T12807 T12804 arg2Of mechanisms,mediates
R7968 T12807 T12805 arg1Of mechanisms,its
R7969 T12807 T12806 arg1Of mechanisms,protective
R7970 T12810 T12809 arg2Of part,in
R7971 T12815 T12812 arg2Of shift,via
R7972 T12815 T12813 arg1Of shift,a
R7973 T12815 T12814 arg1Of shift,rapid
R7974 T12815 T12816 arg1Of shift,from
R7975 T12815 T12818 arg1Of shift,to
R7976 T12817 T12816 arg2Of NFκB-,from
R7977 T12819 T12818 arg2Of PI3K-signaling,to
R7978 T12821 T12820 arg2Of "22,37",[
R7979 T12822 T12820 arg3Of ],[
R7980 T12824 T12823 arg1Of study,Our
R7981 T12824 T12825 arg1Of study,provides
R7982 T12825 T12832 arg1Of provides,and
R7983 T12827 T12825 arg2Of evidence,provides
R7984 T12827 T12826 arg1Of evidence,novel
R7985 T12827 T12829 arg1Of evidence,downstream
R7986 T12829 T12828 arg1Of downstream,that
R7987 T12829 T12830 arg1Of downstream,of
R7988 T12831 T12830 arg2Of recognition,of
R7989 T12837 T12833 arg1Of binding,signaling
R7990 T12837 T12834 arg1Of binding,pro-inflammatory
R7991 T12837 T12835 arg1Of binding,transcription
R7992 T12837 T12836 arg1Of binding,factor
R7993 T12837 T12838 arg1Of binding,and
R7994 T12838 T12844 arg1Of and,is
R7995 T12838 T12845 arg2Of and,switched
R7996 T12840 T12838 arg2Of expression,and
R7997 T12840 T12839 arg1Of expression,cytokine
R7998 T12840 T12841 arg1Of expression,of
R7999 T12843 T12841 arg2Of leukocytes,of
R8000 T12843 T12842 arg1Of leukocytes,human
R8001 T12845 T12832 arg2Of switched,and
R8002 T12845 T12844 arg2Of switched,is
R8003 T12845 T12846 arg1Of switched,to
R8004 T12849 T12846 arg2Of phenotype,to
R8005 T12849 T12847 arg1Of phenotype,an
R8006 T12849 T12848 arg1Of phenotype,anti-inflammatory
R8007 T12849 T12850 arg1Of phenotype,by
R8008 T12851 T12850 arg2Of GP,by
R8009 T12852 T12853 arg1Of We,confirmed
R8010 T12852 T12855 arg1Of We,extended
R8011 T12853 T12854 arg1Of confirmed,and
R8012 T12854 T12861 modOf and,indicating
R8013 T12855 T12854 arg2Of extended,and
R8014 T12857 T12853 arg2Of results,confirmed
R8015 T12857 T12855 arg2Of results,extended
R8016 T12857 T12856 arg1Of results,previous
R8017 T12857 T12858 arg1Of results,[
R8018 T12859 T12858 arg2Of 13-16,[
R8019 T12860 T12858 arg3Of ],[
R8020 T12864 T12865 arg1Of in,the
R8021 T12864 T12867 arg1Of in,of
R8022 T12866 T12864 arg2Of absence,in
R8023 T12869 T12864 arg3Of stimuli,in
R8024 T12869 T12868 arg1Of stimuli,other
R8025 T12871 T12872 arg1Of β-1→3-D-glucans,induced
R8026 T12872 T12861 arg2Of induced,indicating
R8027 T12872 T12862 arg1Of induced,that
R8028 T12872 T12863 arg1Of induced,","
R8029 T12872 T12864 arg1Of induced,in
R8030 T12872 T12870 arg1Of induced,","
R8031 T12873 T12872 arg2Of binding,induced
R8032 T12873 T12874 arg1Of binding,of
R8033 T12873 T12880 arg1Of binding,to
R8034 T12875 T12876 arg1Of NFκB-,","
R8035 T12876 T12878 arg1Of ",",and
R8036 T12877 T12876 arg2Of NFIL-6-,","
R8037 T12878 T12874 arg2Of and,of
R8038 T12879 T12878 arg2Of NFAT-mers,and
R8039 T12882 T12880 arg2Of promoters,to
R8040 T12882 T12881 arg1Of promoters,cytokine
R8041 T12883 T12884 arg1Of Because,of
R8042 T12888 T12883 arg2Of shifts,Because
R8043 T12888 T12885 arg1Of shifts,the
R8044 T12888 T12886 arg1Of shifts,multiple
R8045 T12888 T12887 arg1Of shifts,band
R8046 T12888 T12889 arg2Of shifts,observed
R8047 T12889 T12890 arg1Of observed,for
R8048 T12892 T12890 arg2Of binding,for
R8049 T12892 T12891 arg1Of binding,NFAT
R8050 T12892 T12893 arg1Of binding,(
R8051 T12895 T12893 arg2Of 1A,(
R8052 T12895 T12894 arg1Of 1A,Fig.
R8053 T12896 T12893 arg3Of ),(
R8054 T12898 T12899 arg1Of one,could
R8055 T12898 T12900 arg1Of one,speculate
R8056 T12900 T12883 arg1Of speculate,Because
R8057 T12900 T12897 arg1Of speculate,","
R8058 T12900 T12899 arg2Of speculate,could
R8059 T12902 T12903 arg1Of there,is
R8060 T12903 T12900 arg2Of is,speculate
R8061 T12903 T12901 arg1Of is,that
R8062 T12904 T12903 arg2Of activation,is
R8063 T12904 T12905 arg1Of activation,of
R8064 T12909 T12905 arg2Of isoforms,of
R8065 T12909 T12906 arg1Of isoforms,several
R8066 T12909 T12907 arg1Of isoforms,different
R8067 T12909 T12908 arg1Of isoforms,NFAT
R8068 T12909 T12910 arg1Of isoforms,","
R8069 T12909 T12912 arg2Of isoforms,derived
R8070 T12912 T12911 arg1Of derived,probably
R8071 T12912 T12913 arg1Of derived,from
R8072 T12915 T12913 arg2Of splicing,from
R8073 T12915 T12914 arg1Of splicing,alternative
R8074 T12915 T12916 arg1Of splicing,[
R8075 T12917 T12916 arg2Of 38,[
R8076 T12918 T12916 arg3Of ],[
R8077 T12925 T12921 arg1Of binding,the
R8078 T12925 T12922 arg1Of binding,GP-induced
R8079 T12925 T12923 arg1Of binding,transcription
R8080 T12925 T12924 arg1Of binding,factor
R8081 T12925 T12926 arg1Of binding,transformed
R8082 T12926 T12919 arg1Of transformed,Interestingly
R8083 T12926 T12920 arg1Of transformed,","
R8084 T12926 T12928 arg1Of transformed,into
R8085 T12928 T12927 arg1Of into,only
R8086 T12931 T12930 arg1Of limited,very
R8087 T12933 T12929 arg1Of response,a
R8088 T12933 T12931 arg1Of response,limited
R8089 T12933 T12932 arg1Of response,cytokine
R8090 T12933 T12934 arg1Of response,","
R8091 T12934 T12937 arg1Of ",",and
R8092 T12936 T12934 arg2Of IL-8,","
R8093 T12936 T12935 arg1Of IL-8,namely
R8094 T12937 T12928 arg2Of and,into
R8095 T12938 T12937 arg2Of IL-1RA,and
R8096 T12938 T12939 arg1Of IL-1RA,(
R8097 T12941 T12939 arg2Of 3B,(
R8098 T12941 T12940 arg1Of 3B,Fig.
R8099 T12942 T12939 arg3Of ),(
R8100 T12946 T12945 arg1Of data,our
R8101 T12946 T12947 arg1Of data,are
R8102 T12946 T12948 arg1Of data,in
R8103 T12947 T12943 arg1Of are,Hence
R8104 T12947 T12944 arg1Of are,","
R8105 T12948 T12947 arg2Of in,are
R8106 T12949 T12948 arg2Of aggreement,in
R8107 T12949 T12950 arg1Of aggreement,with
R8108 T12953 T12950 arg2Of reports,with
R8109 T12953 T12951 arg1Of reports,the
R8110 T12953 T12952 arg1Of reports,few
R8111 T12953 T12954 arg1Of reports,describing
R8112 T12957 T12955 arg1Of IL-8,a
R8113 T12957 T12956 arg1Of IL-8,β-1→3-D-glucan-mediated
R8114 T12957 T12958 arg1Of IL-8,[
R8115 T12957 T12961 arg1Of IL-8,and
R8116 T12959 T12958 arg2Of "6,16,19",[
R8117 T12960 T12958 arg3Of ],[
R8118 T12961 T12954 arg2Of and,describing
R8119 T12963 T12961 arg2Of production,and
R8120 T12963 T12962 arg1Of production,IL-1RA
R8121 T12963 T12964 arg1Of production,[
R8122 T12965 T12964 arg2Of 17,[
R8123 T12966 T12964 arg3Of ],[
R8124 T12968 T12967 arg2Of addition,In
R8125 T12971 T12972 arg1Of EMSA/supershift,and
R8126 T12973 T12972 arg2Of immunoblotting,and
R8127 T12974 T12970 arg1Of results,our
R8128 T12974 T12971 arg1Of results,EMSA/supershift
R8129 T12974 T12973 arg1Of results,immunoblotting
R8130 T12974 T12975 arg1Of results,demonstrated
R8131 T12975 T12967 arg1Of demonstrated,In
R8132 T12975 T12969 arg1Of demonstrated,","
R8133 T12975 T12983 arg1Of demonstrated,and
R8134 T12975 T12984 arg1Of demonstrated,to
R8135 T12975 T12990 arg1Of demonstrated,to
R8136 T12979 T12975 arg2Of binding,demonstrated
R8137 T12979 T12976 arg1Of binding,a
R8138 T12979 T12977 arg1Of binding,GP-mediated
R8139 T12979 T12978 arg1Of binding,predominant
R8140 T12979 T12980 arg1Of binding,of
R8141 T12982 T12980 arg2Of p65,of
R8142 T12982 T12981 arg1Of p65,NFκB
R8143 T12987 T12984 arg2Of extent,to
R8144 T12987 T12985 arg1Of extent,a
R8145 T12987 T12986 arg1Of extent,lesser
R8146 T12987 T12988 arg1Of extent,of
R8147 T12989 T12988 arg2Of p50,of
R8148 T12994 T12990 arg2Of site,to
R8149 T12994 T12991 arg1Of site,a
R8150 T12994 T12992 arg1Of site,κB
R8151 T12994 T12993 arg1Of site,consensus
R8152 T12994 T12995 arg1Of site,of
R8153 T12994 T12999 arg1Of site,(
R8154 T12998 T12995 arg2Of promoter,of
R8155 T12998 T12996 arg1Of promoter,the
R8156 T12998 T12997 arg1Of promoter,IL-8
R8157 T13001 T12999 arg2Of 1A,(
R8158 T13001 T13000 arg1Of 1A,Figs.
R8159 T13001 T13002 arg1Of 1A,","
R8160 T13003 T13002 arg2Of 2,","
R8161 T13004 T12999 arg3Of ),(
R8162 T13005 T13006 arg1Of Results,by
R8163 T13005 T13013 arg1Of Results,pointed
R8164 T13007 T13008 arg1Of Schulte,and
R8165 T13008 T13006 arg2Of and,by
R8166 T13009 T13008 arg2Of colleagues,and
R8167 T13009 T13010 arg1Of colleagues,[
R8168 T13011 T13010 arg2Of 28,[
R8169 T13012 T13010 arg3Of ],[
R8170 T13013 T13014 arg1Of pointed,to
R8171 T13013 T13020 arg1Of pointed,depending
R8172 T13013 T13023 arg1Of pointed,via
R8173 T13013 T13031 arg1Of pointed,via
R8174 T13016 T13014 arg2Of induction,to
R8175 T13016 T13015 arg1Of induction,an
R8176 T13016 T13017 arg1Of induction,of
R8177 T13019 T13017 arg2Of transcription,of
R8178 T13019 T13018 arg1Of transcription,IL-8
R8179 T13021 T13020 arg2Of on,depending
R8180 T13022 T13021 arg2Of activation,on
R8181 T13023 T13030 arg1Of via,than
R8182 T13027 T13023 arg2Of homodimer,via
R8183 T13027 T13024 arg1Of homodimer,an
R8184 T13027 T13025 arg1Of homodimer,NFκB
R8185 T13027 T13026 arg1Of homodimer,p65/65
R8186 T13030 T13028 arg1Of than,","
R8187 T13030 T13029 arg1Of than,rather
R8188 T13031 T13030 arg2Of via,than
R8189 T13033 T13031 arg2Of heterodimers,via
R8190 T13033 T13032 arg1Of heterodimers,p65/50
R8191 T13033 T13034 arg1Of heterodimers,","
R8192 T13033 T13035 arg1Of heterodimers,which
R8193 T13033 T13036 arg1Of heterodimers,might
R8194 T13033 T13037 arg1Of heterodimers,be
R8195 T13037 T13036 arg2Of be,might
R8196 T13039 T13037 arg2Of case,be
R8197 T13039 T13038 arg1Of case,the
R8198 T13039 T13040 arg1Of case,for
R8199 T13044 T13040 arg2Of transcription,for
R8200 T13044 T13041 arg1Of transcription,the
R8201 T13044 T13042 arg1Of transcription,GP-mediated
R8202 T13044 T13043 arg1Of transcription,IL-8
R8203 T13048 T13045 arg1Of transcription,A
R8204 T13048 T13046 arg1Of transcription,GP-mediated
R8205 T13048 T13047 arg1Of transcription,IL-8
R8206 T13048 T13049 arg2Of transcription,based
R8207 T13048 T13073 arg1Of transcription,seems
R8208 T13048 T13075 arg1Of transcription,possible
R8209 T13049 T13050 arg1Of based,upon
R8210 T13052 T13050 arg2Of cooperation,upon
R8211 T13052 T13051 arg1Of cooperation,a
R8212 T13052 T13053 arg1Of cooperation,between
R8213 T13056 T13054 arg2Of p65,transactivated
R8214 T13056 T13055 arg1Of p65,NFκB
R8215 T13056 T13057 arg1Of p65,and
R8216 T13057 T13062 arg1Of and,or
R8217 T13058 T13057 arg2Of NFIL-6,and
R8218 T13058 T13059 arg1Of NFIL-6,[
R8219 T13060 T13059 arg2Of "13,39",[
R8220 T13061 T13059 arg3Of ],[
R8221 T13062 T13053 arg2Of or,between
R8222 T13064 T13062 arg2Of dimer,or
R8223 T13064 T13063 arg1Of dimer,NFATc2
R8224 T13064 T13065 arg1Of dimer,binding
R8225 T13065 T13066 arg1Of binding,to
R8226 T13065 T13070 arg1Of binding,[
R8227 T13069 T13066 arg2Of site,to
R8228 T13069 T13067 arg1Of site,the
R8229 T13069 T13068 arg1Of site,IL-8κB
R8230 T13071 T13070 arg2Of 38,[
R8231 T13072 T13070 arg3Of ],[
R8232 T13073 T13074 arg1Of seems,also
R8233 T13075 T13073 arg2Of possible,seems
R8234 T13079 T13076 arg1Of site,The
R8235 T13079 T13077 arg1Of site,IL-8κB
R8236 T13079 T13078 arg1Of site,consensus
R8237 T13079 T13080 arg1Of site,exhibits
R8238 T13079 T13089 arg1Of site,differs
R8239 T13080 T13087 arg1Of exhibits,and
R8240 T13084 T13083 arg1Of binding,p65
R8241 T13085 T13082 arg1Of half,preferentially
R8242 T13085 T13084 arg1Of half,binding
R8243 T13086 T13080 arg2Of site,exhibits
R8244 T13086 T13081 arg1Of site,a
R8245 T13086 T13085 arg1Of site,half
R8246 T13087 T13103 arg1Of and,","
R8247 T13087 T13104 modOf and,supporting
R8248 T13087 T13126 arg1Of and,[
R8249 T13089 T13087 arg2Of differs,and
R8250 T13089 T13088 arg1Of differs,thus
R8251 T13089 T13090 arg1Of differs,from
R8252 T13094 T13090 arg2Of site,from
R8253 T13094 T13091 arg1Of site,the
R8254 T13094 T13092 arg1Of site,κB
R8255 T13094 T13093 arg1Of site,half
R8256 T13094 T13095 arg2Of site,described
R8257 T13095 T13096 arg1Of described,for
R8258 T13097 T13098 arg1Of TNFα,and
R8259 T13098 T13096 arg2Of and,for
R8260 T13099 T13098 arg2Of IL-1β,and
R8261 T13099 T13100 arg1Of IL-1β,[
R8262 T13101 T13100 arg2Of "27,40",[
R8263 T13102 T13100 arg3Of ],[
R8264 T13106 T13105 arg1Of idea,the
R8265 T13106 T13107 arg1Of idea,of
R8266 T13106 T13117 arg1Of idea,and
R8267 T13108 T13107 arg2Of regulating,of
R8268 T13108 T13111 arg1Of regulating,through
R8269 T13110 T13108 arg2Of binding,regulating
R8270 T13110 T13109 arg1Of binding,NFκB
R8271 T13113 T13111 arg2Of associations,through
R8272 T13113 T13112 arg1Of associations,combinatorial
R8273 T13113 T13114 arg1Of associations,of
R8274 T13116 T13114 arg2Of subunits,of
R8275 T13116 T13115 arg1Of subunits,the
R8276 T13117 T13104 arg2Of and,supporting
R8277 T13120 T13117 arg2Of sequence,and
R8278 T13120 T13118 arg1Of sequence,the
R8279 T13120 T13119 arg1Of sequence,specific
R8280 T13120 T13121 arg1Of sequence,of
R8281 T13125 T13121 arg2Of motif,of
R8282 T13125 T13122 arg1Of motif,the
R8283 T13125 T13123 arg1Of motif,decameric
R8284 T13125 T13124 arg1Of motif,κB
R8285 T13127 T13126 arg2Of "41,42",[
R8286 T13128 T13126 arg3Of ],[
R8287 T13130 T13131 arg1Of LPS,or
R8288 T13131 T13129 arg2Of or,Unlike
R8289 T13132 T13131 arg2Of TSST-1,or
R8290 T13134 T13135 arg1Of we,found
R8291 T13135 T13129 arg1Of found,Unlike
R8292 T13135 T13133 arg1Of found,","
R8293 T13137 T13138 arg1Of GP,did
R8294 T13137 T13140 arg1Of GP,induce
R8295 T13140 T13138 arg2Of induce,did
R8296 T13140 T13139 arg1Of induce,not
R8297 T13140 T13143 arg1Of induce,but
R8298 T13141 T13140 arg2Of IL-1β,induce
R8299 T13143 T13135 arg2Of but,found
R8300 T13143 T13136 arg1Of but,that
R8301 T13143 T13142 arg1Of but,","
R8302 T13144 T13146 arg1Of it,induced
R8303 T13146 T13143 arg2Of induced,but
R8304 T13146 T13145 arg1Of induced,strongly
R8305 T13146 T13148 arg1Of induced,","
R8306 T13146 T13149 modOf induced,suggesting
R8307 T13147 T13146 arg2Of IL-1RA,induced
R8308 T13153 T13149 arg2Of potential,suggesting
R8309 T13153 T13150 arg1Of potential,an
R8310 T13153 T13151 arg1Of potential,immediate
R8311 T13153 T13152 arg1Of potential,anti-inflammatory
R8312 T13153 T13154 arg1Of potential,of
R8313 T13155 T13154 arg2Of GP,of
R8314 T13159 T13156 arg2Of promoter,Analysing
R8315 T13159 T13157 arg1Of promoter,the
R8316 T13159 T13158 arg1Of promoter,IL-1RA
R8317 T13159 T13160 arg1Of promoter,[
R8318 T13161 T13160 arg2Of 34,[
R8319 T13162 T13160 arg3Of ],[
R8320 T13164 T13156 arg1Of we,Analysing
R8321 T13164 T13165 arg1Of we,discovered
R8322 T13165 T13156 modOf discovered,Analysing
R8323 T13165 T13163 arg1Of discovered,","
R8324 T13169 T13165 arg2Of sites,discovered
R8325 T13169 T13166 arg1Of sites,four
R8326 T13169 T13167 arg1Of sites,new
R8327 T13169 T13168 arg1Of sites,binding
R8328 T13169 T13170 arg1Of sites,(
R8329 T13169 T13174 arg1Of sites,:
R8330 T13171 T13170 arg2Of Fig.,(
R8331 T13171 T13172 arg1Of Fig.,8
R8332 T13173 T13170 arg3Of ),(
R8333 T13177 T13174 arg2Of site,:
R8334 T13177 T13175 arg1Of site,an
R8335 T13177 T13176 arg1Of site,NFκB3
R8336 T13177 T13178 arg1Of site,(
R8337 T13177 T13184 arg1Of site,","
R8338 T13177 T13194 arg1Of site,","
R8339 T13179 T13178 arg2Of between,(
R8340 T13180 T13181 arg1Of -100,and
R8341 T13181 T13179 arg2Of and,between
R8342 T13182 T13181 arg2Of -130,and
R8343 T13183 T13178 arg3Of ),(
R8344 T13188 T13184 arg2Of site,","
R8345 T13188 T13185 arg1Of site,an
R8346 T13188 T13186 arg1Of site,NFκB
R8347 T13188 T13187 arg1Of site,consensus
R8348 T13188 T13189 arg1Of site,(
R8349 T13190 T13191 arg1Of -266,and
R8350 T13191 T13189 arg2Of and,(
R8351 T13192 T13191 arg2Of -280,and
R8352 T13193 T13189 arg3Of ),(
R8353 T13197 T13195 arg1Of site,another
R8354 T13197 T13196 arg1Of site,NFκB2/3
R8355 T13197 T13198 arg1Of site,(
R8356 T13197 T13203 arg1Of site,and
R8357 T13199 T13200 arg1Of -288,and
R8358 T13200 T13198 arg2Of and,(
R8359 T13201 T13200 arg2Of -302,and
R8360 T13202 T13198 arg3Of ),(
R8361 T13203 T13194 arg2Of and,","
R8362 T13206 T13205 arg1Of distal,more
R8363 T13208 T13203 arg2Of site,and
R8364 T13208 T13204 arg1Of site,a
R8365 T13208 T13206 arg1Of site,distal
R8366 T13208 T13207 arg1Of site,NFATP2/3
R8367 T13208 T13209 arg1Of site,(
R8368 T13210 T13211 arg1Of -471,and
R8369 T13211 T13209 arg2Of and,(
R8370 T13212 T13211 arg2Of -490,and
R8371 T13213 T13209 arg3Of ),(
R8372 T13215 T13214 arg1Of data,Our
R8373 T13215 T13216 arg1Of data,indicated
R8374 T13218 T13219 arg1Of GP,leads
R8375 T13219 T13216 arg2Of leads,indicated
R8376 T13219 T13217 arg1Of leads,that
R8377 T13219 T13220 arg1Of leads,to
R8378 T13219 T13225 arg1Of leads,via
R8379 T13221 T13220 arg2Of production,to
R8380 T13221 T13222 arg1Of production,of
R8381 T13223 T13222 arg2Of IL-1RA,of
R8382 T13225 T13224 arg1Of via,primarily
R8383 T13226 T13225 arg2Of induction,via
R8384 T13226 T13227 arg1Of induction,of
R8385 T13228 T13229 arg1Of NFATP2/3,and
R8386 T13230 T13229 arg2Of NFIL-6,and
R8387 T13232 T13227 arg2Of binding,of
R8388 T13232 T13228 arg1Of binding,NFATP2/3
R8389 T13232 T13230 arg1Of binding,NFIL-6
R8390 T13232 T13231 arg1Of binding,DNA
R8391 T13232 T13233 arg1Of binding,","
R8392 T13232 T13234 arg1Of binding,which
R8393 T13232 T13235 arg1Of binding,might
R8394 T13232 T13236 arg1Of binding,be
R8395 T13232 T13238 arg1Of binding,to
R8396 T13236 T13235 arg2Of be,might
R8397 T13238 T13236 arg2Of to,be
R8398 T13238 T13237 arg1Of to,due
R8399 T13239 T13238 arg2Of differences,to
R8400 T13239 T13240 arg1Of differences,in
R8401 T13239 T13255 arg1Of differences,between
R8402 T13243 T13241 arg1Of motif,the
R8403 T13243 T13242 arg1Of motif,binding
R8404 T13243 T13244 arg1Of motif,or
R8405 T13244 T13240 arg2Of or,in
R8406 T13246 T13244 arg2Of composition,or
R8407 T13246 T13245 arg1Of composition,the
R8408 T13246 T13247 arg1Of composition,of
R8409 T13251 T13247 arg2Of factors,of
R8410 T13251 T13248 arg1Of factors,the
R8411 T13251 T13249 arg2Of factors,activated
R8412 T13251 T13250 arg1Of factors,transcription
R8413 T13251 T13252 arg1Of factors,(
R8414 T13253 T13252 arg2Of NFAT,(
R8415 T13254 T13252 arg3Of ),(
R8416 T13257 T13258 arg1Of IFNγ,","
R8417 T13258 T13260 arg1Of ",",and
R8418 T13259 T13258 arg2Of IL-6,","
R8419 T13260 T13255 arg2Of and,between
R8420 T13260 T13256 arg1Of and,the
R8421 T13262 T13260 arg2Of promoter,and
R8422 T13262 T13261 arg1Of promoter,IL-1RA
R8423 T13265 T13263 arg1Of decrease,The
R8424 T13265 T13264 arg1Of decrease,differential
R8425 T13265 T13266 arg1Of decrease,of
R8426 T13265 T13275 arg1Of decrease,in
R8427 T13265 T13282 arg1Of decrease,of
R8428 T13265 T13287 arg2Of decrease,induced
R8429 T13265 T13295 arg1Of decrease,might
R8430 T13265 T13296 arg1Of decrease,suggest
R8431 T13267 T13268 arg1Of NFκB,","
R8432 T13268 T13270 arg1Of ",",and
R8433 T13269 T13268 arg2Of NFAT,","
R8434 T13270 T13266 arg2Of and,of
R8435 T13272 T13270 arg2Of binding,and
R8436 T13272 T13271 arg1Of binding,NFIL-6
R8437 T13272 T13273 arg1Of binding,to
R8438 T13274 T13273 arg2Of sites,to
R8439 T13275 T13281 arg1Of in,as
R8440 T13278 T13275 arg2Of promoter,in
R8441 T13278 T13276 arg1Of promoter,the
R8442 T13278 T13277 arg1Of promoter,IL-1RA
R8443 T13281 T13279 arg1Of as,as
R8444 T13281 T13280 arg1Of as,well
R8445 T13282 T13281 arg2Of of,as
R8446 T13284 T13283 arg1Of mRNA,IL-1RA
R8447 T13284 T13285 arg1Of mRNA,and
R8448 T13285 T13282 arg2Of and,of
R8449 T13286 T13285 arg2Of protein,and
R8450 T13290 T13287 arg1Of inhibitors,induced
R8451 T13290 T13288 arg2Of inhibitors,by
R8452 T13290 T13289 arg1Of inhibitors,selective
R8453 T13290 T13292 arg1Of inhibitors,to
R8454 T13292 T13291 arg1Of to,prior
R8455 T13294 T13292 arg2Of treatment,to
R8456 T13294 T13293 arg1Of treatment,GP
R8457 T13296 T13295 arg2Of suggest,might
R8458 T13299 T13298 arg1Of steps,these
R8459 T13299 T13300 arg1Of steps,are
R8460 T13299 T13301 arg2Of steps,linked
R8461 T13301 T13296 arg2Of linked,suggest
R8462 T13301 T13297 arg1Of linked,that
R8463 T13301 T13300 arg2Of linked,are
R8464 T13301 T13302 arg1Of linked,to
R8465 T13304 T13305 arg1Of other,and
R8466 T13305 T13307 arg1Of and,for
R8467 T13306 T13305 arg2Of necessary,and
R8468 T13308 T13302 arg2Of induction,to
R8469 T13308 T13303 arg1Of induction,each
R8470 T13308 T13304 arg1Of induction,other
R8471 T13308 T13306 arg1Of induction,necessary
R8472 T13308 T13309 arg1Of induction,of
R8473 T13310 T13309 arg2Of IL-1RA,of
R8474 T13310 T13311 arg1Of IL-1RA,(
R8475 T13312 T13311 arg2Of Fig.,(
R8476 T13312 T13313 arg1Of Fig.,7
R8477 T13314 T13311 arg3Of ),(
R8478 T13317 T13315 arg2Of sources,Regarding
R8479 T13317 T13316 arg1Of sources,cellular
R8480 T13321 T13324 arg1Of monocytes,as
R8481 T13324 T13315 arg1Of as,Regarding
R8482 T13324 T13322 arg1Of as,as
R8483 T13324 T13323 arg1Of as,well
R8484 T13324 T13326 arg1Of as,have
R8485 T13324 T13327 arg1Of as,been
R8486 T13324 T13328 arg2Of as,reported
R8487 T13324 T13330 arg1Of as,produce
R8488 T13325 T13324 arg2Of neutrophils,as
R8489 T13328 T13315 modOf reported,Regarding
R8490 T13328 T13318 arg1Of reported,","
R8491 T13328 T13319 arg1Of reported,both
R8492 T13328 T13320 arg1Of reported,","
R8493 T13328 T13326 arg2Of reported,have
R8494 T13328 T13327 arg2Of reported,been
R8495 T13330 T13328 arg3Of produce,reported
R8496 T13330 T13329 arg1Of produce,to
R8497 T13330 T13332 arg1Of produce,[
R8498 T13331 T13330 arg2Of IL-1RA,produce
R8499 T13333 T13332 arg2Of 32,[
R8500 T13334 T13332 arg3Of ],[
R8501 T13337 T13335 arg1Of experiments,Flow
R8502 T13337 T13336 arg1Of experiments,cytometric
R8503 T13337 T13338 arg1Of experiments,seemed
R8504 T13337 T13340 arg1Of experiments,confirm
R8505 T13340 T13338 arg2Of confirm,seemed
R8506 T13340 T13339 arg1Of confirm,to
R8507 T13342 T13343 arg1Of monocytes,and
R8508 T13343 T13345 arg1Of and,were
R8509 T13343 T13346 arg1Of and,able
R8510 T13343 T13348 arg1Of and,produce
R8511 T13344 T13343 arg2Of neutrophils,and
R8512 T13345 T13340 arg2Of were,confirm
R8513 T13345 T13341 arg1Of were,that
R8514 T13346 T13345 arg2Of able,were
R8515 T13348 T13346 arg2Of produce,able
R8516 T13348 T13347 arg1Of produce,to
R8517 T13348 T13351 arg1Of produce,as
R8518 T13348 T13353 arg1Of produce,in
R8519 T13349 T13348 arg2Of IL-8,produce
R8520 T13351 T13350 arg1Of as,just
R8521 T13352 T13351 arg2Of IL-1RA,as
R8522 T13354 T13353 arg2Of response,in
R8523 T13354 T13355 arg1Of response,to
R8524 T13356 T13355 arg2Of GP,to
R8525 T13356 T13357 arg1Of GP,(
R8526 T13358 T13357 arg2Of data,(
R8527 T13358 T13360 arg2Of data,shown
R8528 T13360 T13359 arg1Of shown,not
R8529 T13361 T13357 arg3Of ),(
R8530 T13365 T13362 arg1Of profile,This
R8531 T13365 T13363 arg1Of profile,GP-induced
R8532 T13365 T13364 arg1Of profile,cytokine
R8533 T13365 T13366 arg1Of profile,was
R8534 T13365 T13369 arg1Of profile,restricted
R8535 T13368 T13367 arg1Of more,substantially
R8536 T13369 T13366 arg2Of restricted,was
R8537 T13369 T13368 arg1Of restricted,more
R8538 T13369 T13370 arg1Of restricted,than
R8539 T13371 T13370 arg2Of that,than
R8540 T13371 T13372 arg1Of that,of
R8541 T13373 T13374 arg1Of LPS,or
R8542 T13374 T13372 arg2Of or,of
R8543 T13374 T13376 arg1Of or,","
R8544 T13374 T13377 arg1Of or,which
R8545 T13374 T13378 arg1Of or,is
R8546 T13374 T13380 arg1Of or,due
R8547 T13375 T13374 arg2Of TSST-1,or
R8548 T13380 T13378 arg2Of due,is
R8549 T13380 T13379 arg1Of due,likely
R8550 T13380 T13381 arg1Of due,to
R8551 T13382 T13381 arg2Of differences,to
R8552 T13382 T13383 arg1Of differences,in
R8553 T13384 T13385 arg1Of recognition,and
R8554 T13385 T13383 arg2Of and,in
R8555 T13385 T13387 arg1Of and,between
R8556 T13386 T13385 arg2Of signaling,and
R8557 T13388 T13389 arg1Of LPS,","
R8558 T13389 T13391 arg1Of ",",and
R8559 T13390 T13389 arg2Of TSST-1,","
R8560 T13391 T13387 arg2Of and,between
R8561 T13392 T13391 arg2Of GP,and
R8562 T13393 T13394 arg1Of Recognition,of
R8563 T13393 T13396 arg1Of Recognition,is
R8564 T13393 T13398 arg2Of Recognition,mediated
R8565 T13395 T13394 arg2Of LPS,of
R8566 T13398 T13396 arg2Of mediated,is
R8567 T13398 T13397 arg1Of mediated,mainly
R8568 T13398 T13399 arg1Of mediated,through
R8569 T13398 T13410 arg1Of mediated,","
R8570 T13398 T13411 modOf mediated,leading
R8571 T13398 T13419 arg1Of mediated,[
R8572 T13401 T13400 arg1Of receptor,Toll-like
R8573 T13401 T13402 arg1Of receptor,4
R8574 T13401 T13403 arg1Of receptor,and
R8575 T13403 T13399 arg2Of and,through
R8576 T13403 T13406 arg1Of and,via
R8577 T13405 T13403 arg2Of signaling,and
R8578 T13405 T13404 arg1Of signaling,subsequent
R8579 T13409 T13406 arg2Of pathway,via
R8580 T13409 T13407 arg1Of pathway,the
R8581 T13409 T13408 arg1Of pathway,NFκB
R8582 T13411 T13412 arg1Of leading,to
R8583 T13413 T13412 arg2Of expression,to
R8584 T13413 T13414 arg1Of expression,of
R8585 T13416 T13414 arg2Of mediators,of
R8586 T13416 T13415 arg1Of mediators,pro-inflammatory
R8587 T13416 T13417 arg1Of mediators,like
R8588 T13418 T13417 arg2Of TNFα,like
R8589 T13420 T13419 arg2Of 43,[
R8590 T13421 T13419 arg3Of ],[
R8591 T13424 T13422 arg1Of superantigen,A
R8592 T13424 T13423 arg1Of superantigen,bacterial
R8593 T13424 T13425 arg1Of superantigen,like
R8594 T13424 T13427 arg1Of superantigen,acts
R8595 T13426 T13425 arg2Of TSST-1,like
R8596 T13427 T13428 arg1Of acts,through
R8597 T13427 T13439 arg1Of acts,","
R8598 T13427 T13440 modOf acts,leading
R8599 T13427 T13451 arg1Of acts,via
R8600 T13427 T13460 arg1Of acts,[
R8601 T13429 T13430 arg1Of binding,to
R8602 T13429 T13433 arg1Of binding,and
R8603 T13432 T13430 arg2Of molecules,to
R8604 T13432 T13431 arg1Of molecules,MHC-II
R8605 T13433 T13428 arg2Of and,through
R8606 T13436 T13435 arg1Of T,the
R8607 T13437 T13434 arg1Of cell,subsequently
R8608 T13437 T13436 arg1Of cell,T
R8609 T13438 T13433 arg2Of receptor,and
R8610 T13438 T13437 arg1Of receptor,cell
R8611 T13440 T13441 arg1Of leading,to
R8612 T13442 T13441 arg2Of release,to
R8613 T13442 T13443 arg1Of release,of
R8614 T13445 T13446 arg1Of IFNγ,and
R8615 T13446 T13443 arg2Of and,of
R8616 T13446 T13444 arg1Of and,mainly
R8617 T13446 T13448 arg1Of and,","
R8618 T13447 T13446 arg2Of TNFα,and
R8619 T13450 T13448 arg2Of latter,","
R8620 T13450 T13449 arg1Of latter,the
R8621 T13451 T13452 arg1Of via,both
R8622 T13454 T13455 arg1Of PI3K,and
R8623 T13456 T13455 arg2Of p38,and
R8624 T13459 T13451 arg2Of signaling,via
R8625 T13459 T13453 arg1Of signaling,","
R8626 T13459 T13454 arg1Of signaling,PI3K
R8627 T13459 T13456 arg1Of signaling,p38
R8628 T13459 T13457 arg1Of signaling,mitogen-activated
R8629 T13459 T13458 arg1Of signaling,kinase
R8630 T13461 T13460 arg2Of "44,45",[
R8631 T13462 T13460 arg3Of ],[
R8632 T13466 T13465 arg1Of induction,the
R8633 T13466 T13467 arg1Of induction,of
R8634 T13466 T13475 arg1Of induction,by
R8635 T13466 T13481 arg1Of induction,may
R8636 T13466 T13483 arg1Of induction,fit
R8637 T13466 T13490 arg1Of induction,mounting
R8638 T13470 T13468 arg1Of IL-8,the
R8639 T13470 T13469 arg1Of IL-8,neutrophil-attracting
R8640 T13470 T13471 arg1Of IL-8,and
R8641 T13471 T13467 arg2Of and,of
R8642 T13474 T13471 arg2Of IL-1RA,and
R8643 T13474 T13472 arg1Of IL-1RA,the
R8644 T13474 T13473 arg1Of IL-1RA,anti-inflammatory
R8645 T13477 T13475 arg2Of carbohydrates,by
R8646 T13477 T13476 arg1Of carbohydrates,fungal
R8647 T13477 T13478 arg1Of carbohydrates,(
R8648 T13479 T13478 arg2Of GP,(
R8649 T13480 T13478 arg3Of ),(
R8650 T13483 T13463 arg1Of fit,Altogether
R8651 T13483 T13464 arg1Of fit,","
R8652 T13483 T13481 arg2Of fit,may
R8653 T13483 T13482 arg1Of fit,well
R8654 T13483 T13484 arg1Of fit,to
R8655 T13483 T13489 arg1Of fit,","
R8656 T13483 T13490 modOf fit,mounting
R8657 T13488 T13484 arg2Of response,to
R8658 T13488 T13485 arg1Of response,a
R8659 T13488 T13486 arg1Of response,benign
R8660 T13488 T13487 arg1Of response,PAMP
R8661 T13490 T13493 arg1Of mounting,against
R8662 T13492 T13490 arg2Of mechanisms,mounting
R8663 T13492 T13491 arg1Of mechanisms,defensive
R8664 T13497 T13493 arg2Of attack,against
R8665 T13497 T13494 arg1Of attack,a
R8666 T13497 T13495 arg1Of attack,possible
R8667 T13497 T13496 arg1Of attack,microbial
R8668 T13500 T13498 arg1Of more,Potentially
R8669 T13500 T13499 arg1Of more,even
R8670 T13501 T13500 arg1Of relevant,more
R8671 T13501 T13502 arg1Of relevant,than
R8672 T13506 T13503 arg1Of panel,the
R8673 T13506 T13504 arg1Of panel,specific
R8674 T13506 T13505 arg1Of panel,cytokine
R8675 T13506 T13507 arg2Of panel,induced
R8676 T13506 T13510 arg1Of panel,","
R8677 T13506 T13512 arg1Of panel,found
R8678 T13509 T13507 arg1Of GP,induced
R8679 T13509 T13508 arg2Of GP,by
R8680 T13511 T13510 arg2Of we,","
R8681 T13512 T13502 arg2Of found,than
R8682 T13517 T13515 arg2Of presence,in
R8683 T13517 T13516 arg1Of presence,the
R8684 T13517 T13518 arg1Of presence,of
R8685 T13520 T13518 arg2Of stimuli,of
R8686 T13520 T13519 arg1Of stimuli,other
R8687 T13520 T13521 arg1Of stimuli,(
R8688 T13522 T13523 arg1Of LPS,or
R8689 T13523 T13521 arg2Of or,(
R8690 T13524 T13523 arg2Of TSST-1,or
R8691 T13525 T13521 arg3Of ),(
R8692 T13527 T13528 arg1Of GP,ameliorated
R8693 T13528 T13512 arg2Of ameliorated,found
R8694 T13528 T13513 arg1Of ameliorated,that
R8695 T13528 T13514 arg1Of ameliorated,","
R8696 T13528 T13515 arg1Of ameliorated,in
R8697 T13528 T13526 arg1Of ameliorated,","
R8698 T13528 T13533 arg1Of ameliorated,","
R8699 T13532 T13528 arg2Of reactions,ameliorated
R8700 T13532 T13529 arg1Of reactions,their
R8701 T13532 T13530 arg1Of reactions,pro-inflammatory
R8702 T13532 T13531 arg1Of reactions,immune
R8703 T13532 T13534 arg1Of reactions,similar
R8704 T13534 T13528 arg3Of similar,ameliorated
R8705 T13534 T13535 arg1Of similar,to
R8706 T13537 T13535 arg2Of effects,to
R8707 T13537 T13536 arg1Of effects,the
R8708 T13537 T13538 arg1Of effects,in
R8709 T13540 T13538 arg2Of models,in
R8710 T13540 T13539 arg1Of models,murine
R8711 T13540 T13541 arg1Of models,of
R8712 T13542 T13543 arg1Of sepsis,and
R8713 T13543 T13541 arg2Of and,of
R8714 T13543 T13545 arg1Of and,[
R8715 T13544 T13543 arg2Of inflammation,and
R8716 T13546 T13545 arg2Of 21-24,[
R8717 T13547 T13545 arg3Of ],[
R8718 T13550 T13551 arg1Of GP,altered
R8719 T13551 T13548 arg1Of altered,Mainly
R8720 T13551 T13549 arg1Of altered,","
R8721 T13551 T13556 arg1Of altered,from
R8722 T13551 T13559 arg1Of altered,to
R8723 T13551 T13563 arg1Of altered,via
R8724 T13551 T13569 arg1Of altered,","
R8725 T13551 T13570 arg1Of altered,at
R8726 T13555 T13551 arg2Of ratio,altered
R8727 T13555 T13552 arg1Of ratio,the
R8728 T13555 T13553 arg1Of ratio,TSST-1-induced
R8729 T13555 T13554 arg1Of ratio,IL-1β/IL-1RA
R8730 T13558 T13556 arg2Of pro-,from
R8731 T13558 T13557 arg1Of pro-,a
R8732 T13562 T13559 arg2Of profile,to
R8733 T13562 T13560 arg1Of profile,an
R8734 T13562 T13561 arg1Of profile,anti-inflammatory
R8735 T13564 T13563 arg2Of down-regulation,via
R8736 T13564 T13565 arg1Of down-regulation,of
R8737 T13566 T13567 arg1Of IL-1β,and
R8738 T13567 T13565 arg2Of and,of
R8739 T13568 T13567 arg2Of IL-6,and
R8740 T13573 T13570 arg2Of time,at
R8741 T13573 T13571 arg1Of time,the
R8742 T13573 T13572 arg1Of time,same
R8743 T13574 T13575 arg1Of there,was
R8744 T13575 T13573 arg2Of was,time
R8745 T13578 T13575 arg2Of up-regulation,was
R8746 T13578 T13576 arg1Of up-regulation,a
R8747 T13578 T13577 arg1Of up-regulation,synergistic
R8748 T13578 T13579 arg1Of up-regulation,of
R8749 T13580 T13579 arg2Of IL-1RA,of
R8750 T13582 T13581 arg2Of part,In
R8751 T13585 T13584 arg1Of change,this
R8752 T13585 T13586 arg1Of change,may
R8753 T13585 T13587 arg1Of change,be
R8754 T13585 T13588 arg2Of change,caused
R8755 T13588 T13581 arg1Of caused,In
R8756 T13588 T13583 arg1Of caused,","
R8757 T13588 T13586 arg2Of caused,may
R8758 T13588 T13587 arg2Of caused,be
R8759 T13588 T13589 arg1Of caused,by
R8760 T13588 T13606 arg1Of caused,up
R8761 T13589 T13605 arg1Of by,and
R8762 T13591 T13589 arg2Of modulations,by
R8763 T13591 T13590 arg1Of modulations,GP-mediated
R8764 T13591 T13592 arg1Of modulations,of
R8765 T13595 T13594 arg1Of induced,TSST-1
R8766 T13596 T13592 arg2Of binding,of
R8767 T13596 T13593 arg1Of binding,the
R8768 T13596 T13595 arg1Of binding,induced
R8769 T13596 T13597 arg1Of binding,of
R8770 T13596 T13603 arg1Of binding,to
R8771 T13598 T13599 arg1Of NFκB,","
R8772 T13599 T13601 arg1Of ",",and
R8773 T13600 T13599 arg2Of NFIL-6,","
R8774 T13601 T13597 arg2Of and,of
R8775 T13602 T13601 arg2Of NFAT,and
R8776 T13604 T13603 arg2Of known,to
R8777 T13606 T13605 arg2Of up,and
R8778 T13606 T13607 arg1Of up,to
R8779 T13610 T13608 arg1Of sites,now
R8780 T13610 T13609 arg1Of sites,unknown
R8781 T13610 T13611 arg1Of sites,within
R8782 T13610 T13618 arg1Of sites,of
R8783 T13613 T13614 arg1Of IL-8,and
R8784 T13615 T13614 arg2Of IL-1RA,and
R8785 T13616 T13611 arg2Of promoter,within
R8786 T13616 T13612 arg1Of promoter,the
R8787 T13616 T13613 arg1Of promoter,IL-8
R8788 T13616 T13615 arg1Of promoter,IL-1RA
R8789 T13618 T13606 arg2Of of,up
R8790 T13618 T13617 arg1Of of,instead
R8791 T13620 T13621 arg1Of TNFα,","
R8792 T13621 T13623 arg1Of ",",","
R8793 T13622 T13621 arg2Of IL-1β,","
R8794 T13623 T13625 arg1Of ",",or
R8795 T13624 T13623 arg2Of IL-6,","
R8796 T13626 T13625 arg2Of IFNγ,or
R8797 T13627 T13618 arg2Of promoter,of
R8798 T13627 T13619 arg1Of promoter,the
R8799 T13627 T13620 arg1Of promoter,TNFα
R8800 T13627 T13622 arg1Of promoter,IL-1β
R8801 T13627 T13624 arg1Of promoter,IL-6
R8802 T13627 T13626 arg1Of promoter,IFNγ
R8803 T13630 T13631 arg1Of we,found
R8804 T13631 T13628 arg1Of found,Accordingly
R8805 T13631 T13629 arg1Of found,","
R8806 T13635 T13633 arg1Of binding,the
R8807 T13635 T13634 arg1Of binding,TSST-1-induced
R8808 T13635 T13636 arg1Of binding,of
R8809 T13635 T13638 arg1Of binding,to
R8810 T13635 T13645 arg1Of binding,correlated
R8811 T13637 T13636 arg2Of NFκB,of
R8812 T13639 T13638 arg2Of sites,to
R8813 T13639 T13640 arg1Of sites,from
R8814 T13643 T13640 arg2Of promoter,from
R8815 T13643 T13641 arg1Of promoter,the
R8816 T13643 T13642 arg1Of promoter,TNFα
R8817 T13645 T13631 arg2Of correlated,found
R8818 T13645 T13632 arg1Of correlated,that
R8819 T13645 T13644 arg1Of correlated,negatively
R8820 T13645 T13646 arg1Of correlated,with
R8821 T13649 T13646 arg2Of enhancement,with
R8822 T13649 T13647 arg1Of enhancement,the
R8823 T13649 T13648 arg1Of enhancement,GP-mediated
R8824 T13649 T13650 arg1Of enhancement,of
R8825 T13654 T13650 arg2Of production,of
R8826 T13654 T13651 arg1Of production,the
R8827 T13654 T13652 arg1Of production,TSST-1-induced
R8828 T13654 T13653 arg1Of production,IL-1RA
R8829 T13654 T13655 arg1Of production,(
R8830 T13656 T13655 arg2Of r,(
R8831 T13656 T13657 arg1Of r,=
R8832 T13656 T13659 arg1Of r,;
R8833 T13656 T13663 arg1Of r,;
R8834 T13657 T13658 arg1Of =,-0.88
R8835 T13660 T13659 arg2Of p,;
R8836 T13660 T13661 arg1Of p,<
R8837 T13660 T13662 arg1Of p,0.01
R8838 T13664 T13663 arg2Of data,;
R8839 T13664 T13666 arg2Of data,shown
R8840 T13666 T13665 arg1Of shown,not
R8841 T13666 T13667 arg1Of shown,in
R8842 T13668 T13667 arg2Of detail,in
R8843 T13669 T13655 arg3Of ),(
R8844 T13675 T13670 arg2Of sites,Of
R8845 T13675 T13671 arg1Of sites,the
R8846 T13675 T13672 arg1Of sites,four
R8847 T13675 T13673 arg2Of sites,examined
R8848 T13675 T13674 arg1Of sites,NFκB
R8849 T13675 T13676 arg1Of sites,from
R8850 T13679 T13676 arg2Of promoter,from
R8851 T13679 T13677 arg1Of promoter,the
R8852 T13679 T13678 arg1Of promoter,IL-1RA
R8853 T13683 T13684 arg1Of TSST-1-,and
R8854 T13685 T13684 arg2Of LPS-induced,and
R8855 T13686 T13681 arg1Of binding,mostly
R8856 T13686 T13682 arg1Of binding,the
R8857 T13686 T13683 arg1Of binding,TSST-1-
R8858 T13686 T13685 arg1Of binding,LPS-induced
R8859 T13686 T13687 arg1Of binding,to
R8860 T13686 T13694 arg1Of binding,to
R8861 T13686 T13700 arg1Of binding,seemed
R8862 T13686 T13702 arg1Of binding,be
R8863 T13686 T13703 arg2Of binding,increased
R8864 T13689 T13688 arg1Of NFκB3,the
R8865 T13689 T13690 arg1Of NFκB3,and
R8866 T13690 T13687 arg2Of and,to
R8867 T13693 T13690 arg2Of binding,and
R8868 T13693 T13691 arg1Of binding,the
R8869 T13693 T13692 arg1Of binding,TSST-1-induced
R8870 T13699 T13694 arg2Of site,to
R8871 T13699 T13695 arg1Of site,the
R8872 T13699 T13696 arg1Of site,new
R8873 T13699 T13697 arg1Of site,NFκB
R8874 T13699 T13698 arg1Of site,consensus
R8875 T13774 T13769 arg2Of motif,within
R8876 T13774 T13770 arg1Of motif,the
R8877 T13774 T13771 arg1Of motif,decameric
R8878 T13774 T13772 arg1Of motif,NFκB
R8879 T13774 T13773 arg1Of motif,binding
R8880 T13700 T13670 arg1Of seemed,Of
R8881 T13777 T13776 arg1Of TNFα,the
R8882 T13777 T13778 arg1Of TNFα,and
R8883 T13700 T13680 arg1Of seemed,","
R8884 T13778 T13775 arg2Of and,between
R8885 T13703 T13700 arg2Of increased,seemed
R8886 T13781 T13778 arg2Of promoter,and
R8887 T13781 T13779 arg1Of promoter,the
R8888 T13781 T13780 arg1Of promoter,IL-1RA
R8889 T13784 T13783 arg2Of NFκB3,for
R8890 T13703 T13701 arg1Of increased,to
R8891 T13787 T13783 arg1Of motif,for
R8892 T13787 T13785 arg1Of motif,the
R8893 T13787 T13786 arg1Of motif,IL-1RA
R8894 T13787 T13788 arg1Of motif,contains
R8895 T13787 T13804 arg1Of motif,see
R8896 T13788 T13803 arg1Of contains,","
R8897 T13790 T13789 arg1Of T,a
R8898 T13790 T13791 arg1Of T,on
R8899 T13790 T13795 arg1Of T,of
R8900 T13703 T13702 arg2Of increased,be
R8901 T13705 T13703 arg1Of GP,increased
R8902 T13792 T13791 arg2Of position,on
R8903 T13792 T13793 arg1Of position,10
R8904 T13795 T13788 arg2Of of,contains
R8905 T13795 T13794 arg1Of of,instead
R8906 T13705 T13704 arg2Of GP,by
R8907 T13709 T13710 arg1Of we,observed
R8908 T13798 T13795 arg2Of C,of
R8909 T13798 T13796 arg1Of C,the
R8910 T13798 T13797 arg2Of C,conserved
R8911 T13798 T13799 arg1Of C,in
R8912 T13802 T13799 arg2Of motif,in
R8913 T13802 T13800 arg1Of motif,the
R8914 T13802 T13801 arg1Of motif,TNFα
R8915 T13803 T13782 arg2Of ",",(
R8916 T13804 T13803 arg2Of see,","
R8917 T13710 T13708 arg2Of observed,while
R8918 T13806 T13804 arg2Of 1,see
R8919 T13806 T13805 arg1Of 1,Table
R8920 T13807 T13782 arg3Of ),(
R8921 T13713 T13711 arg1Of down-regulation,a
R8922 T13810 T13809 arg1Of leading,probably
R8923 T13810 T13811 arg1Of leading,to
R8924 T13810 T13815 arg1Of leading,[
R8925 T13812 T13811 arg2Of differences,to
R8926 T13812 T13813 arg1Of differences,in
R8927 T13814 T13813 arg2Of binding,in
R8928 T13713 T13712 arg1Of down-regulation,GP-mediated
R8929 T13713 T13714 arg1Of down-regulation,of
R8930 T13816 T13815 arg2Of "41,42",[
R8931 T13713 T13717 arg1Of down-regulation,and
R8932 T13817 T13815 arg3Of ],[
R8933 T13716 T13714 arg2Of LPS-,of
R8934 T13820 T13818 arg2Of location,Despite
R8935 T13820 T13819 arg1Of location,the
R8936 T13820 T13821 arg1Of location,of
R8937 T13821 T13832 arg1Of of,in
R8938 T13716 T13715 arg1Of LPS-,the
R8939 T13717 T13710 arg2Of and,observed
R8940 T13720 T13717 arg2Of NFκB,and
R8941 T13826 T13821 arg2Of site,of
R8942 T13826 T13822 arg1Of site,the
R8943 T13826 T13823 arg1Of site,new
R8944 T13826 T13824 arg1Of site,NFκB
R8945 T13826 T13825 arg1Of site,consensus
R8946 T13826 T13827 arg1Of site,(
R8947 T13828 T13829 arg1Of -266,and
R8948 T13829 T13827 arg2Of and,(
R8949 T13830 T13829 arg2Of -280,and
R8950 T13831 T13827 arg3Of ),(
R8951 T13720 T13718 arg1Of NFκB,the
R8952 T13720 T13719 arg1Of NFκB,TSST-1-induced
R8953 T13835 T13832 arg2Of element,in
R8954 T13835 T13833 arg1Of element,the
R8955 T13835 T13834 arg1Of element,inhibitory
R8956 T13835 T13836 arg1Of element,(
R8957 T13835 T13841 arg1Of element,of
R8958 T13720 T13721 arg1Of NFκB,binding
R8959 T13721 T13722 arg1Of binding,to
R8960 T13837 T13838 arg1Of -250,and
R8961 T13838 T13836 arg2Of and,(
R8962 T13839 T13838 arg2Of -294,and
R8963 T13840 T13836 arg3Of ),(
R8964 T13723 T13722 arg2Of sites,to
R8965 T13844 T13841 arg2Of promoter,of
R8966 T13844 T13842 arg1Of promoter,the
R8967 T13844 T13843 arg1Of promoter,IL-1RA
R8968 T13844 T13845 arg1Of promoter,[
R8969 T13846 T13845 arg2Of 30,[
R8970 T13723 T13724 arg1Of sites,of
R8971 T13847 T13845 arg3Of ],[
R8972 T13727 T13724 arg2Of promoter,of
R8973 T13849 T13850 arg1Of we,observed
R8974 T13850 T13818 arg1Of observed,Despite
R8975 T13850 T13848 arg1Of observed,","
R8976 T13727 T13725 arg1Of promoter,the
R8977 T13852 T13850 arg2Of inhibition,observed
R8978 T13852 T13851 arg1Of inhibition,no
R8979 T13727 T13726 arg1Of promoter,TNFα
R8980 T13729 T13730 arg1Of there,was
R8981 T13856 T13853 arg2Of side,On
R8982 T13856 T13854 arg1Of side,the
R8983 T13856 T13855 arg1Of side,other
R8984 T13858 T13859 arg1Of we,found
R8985 T13730 T13706 arg1Of was,So
R8986 T13859 T13853 arg1Of found,On
R8987 T13859 T13857 arg1Of found,","
R8988 T13859 T13869 arg1Of found,towards
R8989 T13859 T13876 arg1Of found,","
R8990 T13859 T13877 modOf found,demonstrating
R8991 T13863 T13859 arg2Of site,found
R8992 T13863 T13860 arg1Of site,an
R8993 T13863 T13861 arg1Of site,inhibitory
R8994 T13863 T13862 arg1Of site,NFκB2/3
R8995 T13863 T13864 arg1Of site,(
R8996 T13865 T13866 arg1Of -288,and
R8997 T13866 T13864 arg2Of and,(
R8998 T13867 T13866 arg2Of -302,and
R8999 T13730 T13707 arg1Of was,","
R9000 T13730 T13708 arg1Of was,while
R9001 T13730 T13728 arg1Of was,","
R9002 T13732 T13730 arg2Of up-regulation,was
R9003 T13868 T13864 arg3Of ),(
R9004 T13732 T13731 arg1Of up-regulation,an
R9005 T13871 T13869 arg2Of end,towards
R9006 T13871 T13870 arg1Of end,the
R9007 T13871 T13872 arg1Of end,of
R9008 T13732 T13733 arg1Of up-regulation,to
R9009 T13734 T13735 arg1Of NFκB3,and
R9010 T13875 T13872 arg2Of element,of
R9011 T13875 T13873 arg1Of element,the
R9012 T13875 T13874 arg1Of element,inhibitory
R9013 T13736 T13735 arg2Of NFκB,and
R9014 T13878 T13877 arg2Of down-regulations,demonstrating
R9015 T13878 T13879 arg1Of down-regulations,of
R9016 T13881 T13882 arg1Of LPS-,and
R9017 T13738 T13733 arg2Of sites,to
R9018 T13883 T13882 arg2Of TSST-1-induced,and
R9019 T13884 T13879 arg2Of binding,of
R9020 T13884 T13880 arg1Of binding,the
R9021 T13884 T13881 arg1Of binding,LPS-
R9022 T13884 T13883 arg1Of binding,TSST-1-induced
R9023 T13884 T13885 arg1Of binding,","
R9024 T13884 T13886 arg1Of binding,which
R9025 T13884 T13887 arg1Of binding,could
R9026 T13884 T13889 arg1Of binding,be
R9027 T13884 T13890 arg2Of binding,altered
R9028 T13738 T13734 arg1Of sites,NFκB3
R9029 T13738 T13736 arg1Of sites,NFκB
R9030 T13890 T13887 arg2Of altered,could
R9031 T13890 T13888 arg1Of altered,not
R9032 T13890 T13889 arg2Of altered,be
R9033 T13738 T13737 arg1Of sites,consensus
R9034 T13892 T13890 arg1Of GP,altered
R9035 T13892 T13891 arg2Of GP,by
R9036 T13738 T13739 arg1Of sites,of
R9037 T13742 T13739 arg2Of promoter,of
R9038 T13895 T13893 arg2Of opinion,In
R9039 T13895 T13894 arg1Of opinion,our
R9040 T13898 T13897 arg1Of site,this
R9041 T13898 T13899 arg1Of site,may
R9042 T13898 T13901 arg1Of site,represent
R9043 T13742 T13740 arg1Of promoter,the
R9044 T13901 T13893 arg1Of represent,In
R9045 T13901 T13896 arg1Of represent,","
R9046 T13901 T13899 arg2Of represent,may
R9047 T13901 T13900 arg1Of represent,therefore
R9048 T13742 T13741 arg1Of promoter,IL-1RA
R9049 T13903 T13902 arg1Of least,at
R9050 T13745 T13744 arg1Of contradictory,seemingly
R9051 T13905 T13901 arg2Of part,represent
R9052 T13905 T13903 arg1Of part,least
R9053 T13905 T13904 arg1Of part,a
R9054 T13905 T13906 arg1Of part,of
R9055 T13746 T13743 arg1Of data,These
R9056 T13911 T13906 arg2Of element,of
R9057 T13911 T13907 arg1Of element,the
R9058 T13911 T13908 arg1Of element,previoulsy
R9059 T13911 T13909 arg2Of element,described
R9060 T13911 T13910 arg1Of element,inhibitory
R9061 T13911 T13912 arg1Of element,[
R9062 T13913 T13912 arg2Of 30,[
R9063 T13746 T13745 arg1Of data,contradictory
R9064 T13914 T13912 arg3Of ],[
R9065 T13746 T13747 arg1Of data,could
R9066 T13746 T13748 arg1Of data,be
R9067 T13746 T13749 arg2Of data,explained
R9068 T13917 T13915 arg1Of increase,The
R9069 T13917 T13916 arg1Of increase,GP-modulated
R9070 T13917 T13918 arg1Of increase,in
R9071 T13917 T13921 arg1Of increase,to
R9072 T13917 T13939 arg1Of increase,to
R9073 T13917 T13944 arg1Of increase,may
R9074 T13917 T13945 arg1Of increase,explain
R9075 T13746 T13810 arg1Of data,leading
R9076 T13920 T13918 arg2Of binding,in
R9077 T13920 T13919 arg1Of binding,TSST-1-induced
R9078 T13921 T13938 arg1Of to,as
R9079 T13749 T13747 arg2Of explained,could
R9080 T13924 T13925 arg1Of NFκB3,and
R9081 T13926 T13925 arg2Of NFκB,and
R9082 T13928 T13921 arg2Of site,to
R9083 T13928 T13922 arg1Of site,the
R9084 T13928 T13923 arg1Of site,new
R9085 T13928 T13924 arg1Of site,NFκB3
R9086 T13928 T13926 arg1Of site,NFκB
R9087 T13928 T13927 arg1Of site,consensus
R9088 T13928 T13929 arg1Of site,","
R9089 T13749 T13748 arg2Of explained,be
R9090 T13932 T13929 arg2Of site,","
R9091 T13932 T13930 arg1Of site,the
R9092 T13932 T13931 arg1Of site,NFIL-6
R9093 T13932 T13933 arg1Of site,[
R9094 T13934 T13933 arg2Of 32,[
R9095 T13935 T13933 arg3Of ],[
R9096 T13749 T13808 arg1Of explained,","
R9097 T13938 T13936 arg1Of as,as
R9098 T13938 T13937 arg1Of as,well
R9099 T13749 T13810 modOf explained,leading
R9100 T13939 T13938 arg2Of to,as
R9101 T13751 T13752 arg1Of differences,in
R9102 T13943 T13939 arg2Of site,to
R9103 T13943 T13940 arg1Of site,the
R9104 T13943 T13941 arg1Of site,novel
R9105 T13943 T13942 arg1Of site,NFATP2/3
R9106 T13751 T13756 arg1Of differences,or
R9107 T13945 T13944 arg2Of explain,may
R9108 T13755 T13752 arg2Of subunits,in
R9109 T13948 T13945 arg2Of up-regulation,explain
R9110 T13948 T13946 arg1Of up-regulation,the
R9111 T13948 T13947 arg1Of up-regulation,synergistic
R9112 T13948 T13949 arg1Of up-regulation,of
R9113 T13953 T13949 arg2Of production,of
R9114 T13953 T13950 arg1Of production,the
R9115 T13953 T13951 arg1Of production,TSST-1-induced
R9116 T13953 T13952 arg1Of production,IL-1RA
R9117 T13954 T13955 arg1Of We,think
R9118 T13755 T13753 arg1Of subunits,either
R9119 T13755 T13754 arg1Of subunits,NFκB
R9120 T13756 T13749 arg1Of or,explained
R9121 T13959 T13957 arg1Of activation,this
R9122 T13959 T13958 arg1Of activation,GP-modulated
R9123 T13959 T13960 arg1Of activation,of
R9124 T13959 T13962 arg1Of activation,was
R9125 T13959 T13963 arg2Of activation,reflected
R9126 T13961 T13960 arg2Of transcription,of
R9127 T13756 T13750 arg2Of or,by
R9128 T13963 T13955 arg2Of reflected,think
R9129 T13963 T13956 arg1Of reflected,that
R9130 T13963 T13962 arg2Of reflected,was
R9131 T13756 T13769 arg1Of or,within
R9132 T13756 T13775 arg1Of or,between
R9133 T13756 T13782 arg1Of or,(
R9134 T13758 T13756 arg2Of nucleotides,or
R9135 T13758 T13757 arg2Of nucleotides,conserved
R9136 T13758 T13759 arg1Of nucleotides,(
R9137 T13761 T13762 arg1Of 1,","
R9138 T13966 T13963 arg1Of decrease,reflected
R9139 T13966 T13964 arg2Of decrease,by
R9140 T13966 T13965 arg1Of decrease,the
R9141 T13966 T13967 arg1Of decrease,of
R9142 T13966 T13971 arg1Of decrease,following
R9143 T13970 T13967 arg2Of ratio,of
R9144 T13970 T13968 arg1Of ratio,the
R9145 T13970 T13969 arg1Of ratio,IL-1β/IL-1RA
R9146 T13974 T13971 arg2Of TSST-1,following
R9147 T13762 T13764 arg1Of ",",","
R9148 T13974 T13972 arg1Of TSST-1,GP
R9149 T13974 T13973 arg1Of TSST-1,+
R9150 T13974 T13975 arg1Of TSST-1,(
R9151 T13763 T13762 arg2Of 2,","
R9152 T13976 T13975 arg2Of Fig.,(
R9153 T13976 T13977 arg1Of Fig.,6
R9154 T13978 T13975 arg3Of ),(
R9155 T13764 T13759 arg2Of ",",(
R9156 T13981 T13979 arg2Of context,In
R9157 T13764 T13760 arg1Of ",",#
R9158 T13981 T13980 arg1Of context,this
R9159 T13764 T13766 arg1Of ",",","
R9160 T13765 T13764 arg2Of 3,","
R9161 T13983 T13984 arg1Of it,has
R9162 T13983 T13985 arg1Of it,been
R9163 T13983 T13986 arg2Of it,postulated
R9164 T13767 T13766 arg2Of 10,","
R9165 T13986 T13979 arg1Of postulated,In
R9166 T13986 T13982 arg1Of postulated,","
R9167 T13986 T13984 arg2Of postulated,has
R9168 T13986 T13985 arg2Of postulated,been
R9169 T13989 T13988 arg1Of vitro,in
R9170 T13768 T13759 arg3Of ),(
R9171 T13992 T13990 arg1Of excess,a
R9172 T13992 T13991 arg1Of excess,100fold
R9173 T13992 T13993 arg1Of excess,of
R9174 T13992 T13995 arg1Of excess,over
R9175 T13992 T13997 arg1Of excess,might
R9176 T13992 T13998 arg1Of excess,control
R9177 T13994 T13993 arg2Of IL-1RA,of
R9178 T14063 T14060 arg1Of effects,The
R9179 T13996 T13995 arg2Of IL-1β,over
R9180 T13998 T13986 arg3Of control,postulated
R9181 T13998 T13987 arg1Of control,that
R9182 T13998 T13989 arg1Of control,vitro
R9183 T13998 T13997 arg2Of control,might
R9184 T14001 T13998 arg2Of effects,control
R9185 T14001 T13999 arg1Of effects,the
R9186 T14001 T14000 arg1Of effects,biological
R9187 T14001 T14002 arg1Of effects,of
R9188 T14003 T14002 arg2Of IL-1,of
R9189 T14003 T14004 arg1Of IL-1,[
R9190 T14005 T14004 arg2Of "46,47",[
R9191 T14006 T14004 arg3Of ],[
R9192 T14007 T14008 arg1Of Since,","
R9193 T14010 T14009 arg2Of fact,in
R9194 T14063 T14061 arg1Of effects,weaker
R9195 T14063 T14062 arg1Of effects,modulating
R9196 T14063 T14064 arg1Of effects,of
R9197 T14063 T14066 arg1Of effects,on
R9198 T14014 T14012 arg1Of ratio,the
R9199 T14014 T14013 arg1Of ratio,IL-1β/IL-1RA
R9200 T14014 T14015 arg1Of ratio,following
R9201 T14014 T14019 arg1Of ratio,is
R9202 T14014 T14021 arg1Of ratio,less
R9203 T14063 T14076 arg1Of effects,may
R9204 T14063 T14077 arg1Of effects,be
R9205 T14018 T14015 arg2Of TSST-1,following
R9206 T14063 T14078 arg2Of effects,attributed
R9207 T14018 T14016 arg1Of TSST-1,GP
R9208 T14018 T14017 arg1Of TSST-1,+
R9209 T14019 T14007 arg2Of is,Since
R9210 T14019 T14009 arg1Of is,in
R9211 T14019 T14011 arg1Of is,","
R9212 T14021 T14019 arg2Of less,is
R9213 T14021 T14020 arg1Of less,partially
R9214 T14021 T14022 arg1Of less,than
R9215 T14065 T14064 arg2Of GP,of
R9216 T14023 T14022 arg2Of 0.01,than
R9217 T14026 T14007 arg1Of is,Since
R9218 T14026 T14024 arg1Of is,","
R9219 T14026 T14027 arg1Of is,not
R9220 T14070 T14066 arg2Of response,on
R9221 T14028 T14026 arg2Of unreasonable,is
R9222 T14030 T14025 arg1Of assume,it
R9223 T14030 T14026 arg1Of assume,is
R9224 T14030 T14028 arg1Of assume,unreasonable
R9225 T14030 T14029 arg1Of assume,to
R9226 T14033 T14032 arg1Of bioactivity,IL-1β
R9227 T14033 T14034 arg1Of bioactivity,is
R9228 T14033 T14035 arg2Of bioactivity,inactivated
R9229 T14035 T14030 arg2Of inactivated,assume
R9230 T14035 T14031 arg1Of inactivated,that
R9231 T14035 T14034 arg2Of inactivated,is
R9232 T14035 T14036 arg1Of inactivated,in
R9233 T14070 T14067 arg1Of response,the
R9234 T14038 T14036 arg2Of system,in
R9235 T14038 T14037 arg1Of system,our
R9236 T14070 T14068 arg1Of response,LPS-induced
R9237 T14070 T14069 arg1Of response,immune
R9238 T14070 T14071 arg2Of response,observed
R9239 T14041 T14042 arg1Of GP,reduced
R9240 T14071 T14072 arg1Of observed,in
R9241 T14042 T14039 arg1Of reduced,Indeed
R9242 T14042 T14040 arg1Of reduced,","
R9243 T14074 T14072 arg2Of study,in
R9244 T14044 T14045 arg1Of TSST-1-induced,","
R9245 T14046 T14045 arg2Of IL-1-dependent,","
R9246 T14048 T14042 arg2Of production,reduced
R9247 T14048 T14043 arg1Of production,the
R9248 T14048 T14044 arg1Of production,TSST-1-induced
R9249 T14048 T14046 arg1Of production,IL-1-dependent
R9250 T14048 T14047 arg1Of production,IL-2
R9251 T14048 T14049 arg1Of production,of
R9252 T14048 T14053 arg1Of production,(
R9253 T14074 T14073 arg1Of study,this
R9254 T14078 T14075 arg1Of attributed,","
R9255 T14052 T14049 arg2Of cells,of
R9256 T14052 T14050 arg1Of cells,murine
R9257 T14052 T14051 arg1Of cells,EL-4
R9258 T14054 T14053 arg2Of data,(
R9259 T14054 T14056 arg2Of data,shown
R9260 T14056 T14055 arg1Of shown,not
R9261 T14056 T14057 arg1Of shown,in
R9262 T14078 T14076 arg2Of attributed,may
R9263 T14058 T14057 arg2Of detail,in
R9264 T14059 T14053 arg3Of ),(
R9265 T14078 T14077 arg2Of attributed,be
R9266 T14078 T14079 arg1Of attributed,to
R9267 T14081 T14080 arg1Of balanced,delicately
R9268 T14082 T14079 arg2Of differences,to
R9269 T14082 T14081 arg1Of differences,balanced
R9270 T14082 T14083 arg1Of differences,in
R9271 T14085 T14083 arg2Of pathways,in
R9272 T14159 T14157 arg3Of ],[
R9273 T14085 T14084 arg1Of pathways,signaling
R9274 T14085 T14086 arg1Of pathways,between
R9275 T14160 T14161 arg1Of Activation,of
R9276 T14160 T14163 arg1Of Activation,can
R9277 T14160 T14165 arg1Of Activation,take
R9278 T14087 T14088 arg1Of LPS,and
R9279 T14162 T14161 arg2Of NFκB,of
R9280 T14165 T14163 arg2Of take,can
R9281 T14165 T14164 arg1Of take,also
R9282 T14165 T14167 arg1Of take,via
R9283 T14088 T14086 arg2Of and,between
R9284 T14166 T14165 arg2Of place,take
R9285 T14168 T14167 arg2Of PI3K,via
R9286 T14168 T14169 arg1Of PI3K,[
R9287 T14168 T14172 arg1Of PI3K,","
R9288 T14168 T14173 arg1Of PI3K,which
R9289 T14168 T14174 arg1Of PI3K,may
R9290 T14168 T14175 arg1Of PI3K,offer
R9291 T14170 T14169 arg2Of 50,[
R9292 T14171 T14169 arg3Of ],[
R9293 T14088 T14090 arg1Of and,[
R9294 T14175 T14174 arg2Of offer,may
R9295 T14089 T14088 arg2Of TSST-1,and
R9296 T14177 T14175 arg2Of explanation,offer
R9297 T14177 T14176 arg1Of explanation,an
R9298 T14177 T14178 arg1Of explanation,for
R9299 T14091 T14090 arg2Of 43-45,[
R9300 T14180 T14178 arg2Of difference,for
R9301 T14180 T14179 arg1Of difference,a
R9302 T14180 T14181 arg1Of difference,in
R9303 T14180 T14183 arg1Of difference,between
R9304 T14182 T14181 arg2Of signaling,in
R9305 T14092 T14090 arg3Of ],[
R9306 T14093 T14094 arg1Of TSST-1,has
R9307 T14093 T14095 arg1Of TSST-1,been
R9308 T14093 T14096 arg2Of TSST-1,shown
R9311 T14093 T14098 arg1Of TSST-1,use
R9313 T14096 T14094 arg2Of shown,has
R9318 T14096 T14095 arg2Of shown,been
R9319 T14096 T14107 arg1Of shown,and
R9321 T14098 T14096 arg3Of use,shown
R9328 T14196 T14199 arg2Of idea,supported
R9329 T14098 T14097 arg1Of use,to
R9330 T14098 T14104 arg1Of use,[
R9331 T14199 T14197 arg2Of supported,may
R9332 T14199 T14198 arg2Of supported,be
R9333 T14101 T14098 arg2Of pathway,use
R9334 T14202 T14199 arg1Of study,supported
R9335 T14202 T14200 arg2Of study,by
R9336 T14202 T14201 arg1Of study,another
R9337 T14202 T14203 arg1Of study,showing
R9338 T14101 T14099 arg1Of pathway,the
R9339 T14207 T14205 arg2Of use,despite
R9340 T14207 T14206 arg1Of use,the
R9341 T14207 T14208 arg1Of use,of
R9342 T14210 T14208 arg2Of PRR,of
R9343 T14210 T14209 arg1Of PRR,similar
R9344 T14101 T14100 arg1Of pathway,PI3K
R9345 T14212 T14213 arg1Of LPS,and
R9346 T14101 T14102 arg1Of pathway,for
R9347 T14213 T14215 arg1Of and,activated
R9348 T14213 T14224 arg1Of and,acted
R9349 T14213 T14229 arg1Of and,suggestive
R9350 T14214 T14213 arg2Of peptidoglycan,and
R9351 T14103 T14102 arg2Of signaling,for
R9352 T14215 T14219 arg1Of activated,through
R9353 T14215 T14223 arg1Of activated,and
R9354 T14218 T14215 arg2Of gene,activated
R9355 T14218 T14216 arg1Of gene,the
R9356 T14218 T14217 arg1Of gene,IL-1RA
R9357 T14105 T14104 arg2Of 44,[
R9358 T14222 T14219 arg2Of proteins,through
R9359 T14222 T14220 arg1Of proteins,different
R9360 T14222 T14221 arg1Of proteins,mechanisms/DNA-binding
R9361 T14223 T14203 arg2Of and,showing
R9362 T14223 T14204 arg1Of and,that
R9363 T14223 T14205 arg1Of and,despite
R9364 T14223 T14211 arg1Of and,","
R9365 T14223 T14228 arg1Of and,","
R9366 T14223 T14229 modOf and,suggestive
R9367 T14224 T14223 arg2Of acted,and
R9368 T14224 T14225 arg1Of acted,synergistically
R9369 T14224 T14226 arg1Of acted,in
R9370 T14106 T14104 arg3Of ],[
R9371 T14227 T14226 arg2Of combination,in
R9372 T14109 T14108 arg1Of effect,this
R9373 T14229 T14230 arg1Of suggestive,of
R9374 T14231 T14230 arg2Of signals,of
R9375 T14231 T14232 arg1Of signals,which
R9376 T14231 T14233 arg1Of signals,are
R9377 T14231 T14235 arg1Of signals,equivalent
R9378 T14233 T14234 arg1Of are,not
R9379 T14233 T14239 arg1Of are,[
R9380 T14109 T14110 arg1Of effect,may
R9381 T14235 T14233 arg2Of equivalent,are
R9382 T14235 T14236 arg1Of equivalent,in
R9383 T14109 T14111 arg1Of effect,be
R9384 T14109 T14112 arg2Of effect,sustained
R9385 T14238 T14236 arg2Of parts,in
R9386 T14238 T14237 arg1Of parts,all
R9387 T14112 T14107 arg2Of sustained,and
R9388 T14240 T14239 arg2Of 51,[
R9389 T14241 T14239 arg3Of ],[
R9390 T14112 T14110 arg2Of sustained,may
R9391 T14112 T14111 arg2Of sustained,be
R9392 T14112 T14116 arg1Of sustained,[
R9393 T14115 T14112 arg1Of treatment,sustained
R9394 T14115 T14113 arg2Of treatment,by
R9395 T14115 T14114 arg1Of treatment,GP
R9396 T14117 T14116 arg2Of "22,37",[
R9397 T14118 T14116 arg3Of ],[
R9398 T14119 T14120 arg1Of It,has
R9399 T14119 T14121 arg1Of It,been
R9400 T14119 T14122 arg2Of It,demonstrated
R9401 T14122 T14120 arg2Of demonstrated,has
R9402 T14122 T14121 arg2Of demonstrated,been
R9403 T14126 T14124 arg2Of leukocytes,in
R9404 T14126 T14125 arg1Of leukocytes,septic/LPS-adapted
R9405 T14129 T14127 arg1Of pathway,the
R9406 T14129 T14128 arg1Of pathway,PI3K
R9407 T14129 T14131 arg1Of pathway,controls
R9408 T14131 T14122 arg3Of controls,demonstrated
R9409 T14131 T14123 arg1Of controls,that
R9410 T14131 T14124 arg1Of controls,in
R9411 T14131 T14130 arg1Of controls,selectively
R9412 T14131 T14137 arg1Of controls,[
R9413 T14132 T14133 arg1Of sIL-1RA,but
R9414 T14133 T14131 arg2Of but,controls
R9415 T14133 T14134 arg1Of but,not
R9416 T14136 T14133 arg2Of production,but
R9417 T14136 T14135 arg1Of production,IL-1β
R9418 T14138 T14137 arg2Of 48,[
R9419 T14139 T14137 arg3Of ],[
R9420 T14140 T14141 arg1Of Signaling,via
R9421 T14140 T14143 arg1Of Signaling,has
R9422 T14140 T14144 arg1Of Signaling,been
R9423 T14140 T14145 arg2Of Signaling,reported
R9424 T14140 T14147 arg1Of Signaling,be
R9425 T14140 T14148 arg2Of Signaling,involved
R9426 T14142 T14141 arg2Of PI3K,via
R9427 T14145 T14143 arg2Of reported,has
R9428 T14145 T14144 arg2Of reported,been
R9429 T14148 T14145 arg3Of involved,reported
R9430 T14148 T14146 arg1Of involved,to
R9431 T14148 T14147 arg2Of involved,be
R9432 T14148 T14149 arg1Of involved,in
R9433 T14148 T14157 arg1Of involved,[
R9434 T14151 T14149 arg2Of activation,in
R9435 T14151 T14150 arg1Of activation,the
R9436 T14151 T14152 arg1Of activation,of
R9437 T14151 T14154 arg1Of activation,in
R9438 T14153 T14152 arg2Of NFAT,of
R9439 T14156 T14154 arg2Of cells,in
R9440 T14156 T14155 arg1Of cells,T
R9441 T14158 T14157 arg2Of 49,[
R11503 T17134 T17133 arg2Of summary,In
R11504 T17137 T17136 arg1Of data,our
R11505 T17137 T17138 arg1Of data,demonstrated
R11506 T17138 T17133 arg1Of demonstrated,In
R11507 T17138 T17135 arg1Of demonstrated,","
R11508 T17141 T17140 arg1Of vitro,in
R11509 T17143 T17141 arg1Of phosphate,vitro
R11510 T17143 T17142 arg1Of phosphate,glucan
R11511 T17143 T17144 arg1Of phosphate,induced
R11512 T17143 T17165 arg1Of phosphate,switched
R11513 T17144 T17162 arg1Of induced,","
R11514 T17148 T17145 arg1Of binding,a
R11515 T17148 T17146 arg1Of binding,transcription
R11516 T17148 T17147 arg1Of binding,factor
R11517 T17148 T17149 arg1Of binding,and
R11518 T17149 T17144 arg2Of and,induced
R11519 T17153 T17149 arg2Of profile,and
R11520 T17153 T17150 arg1Of profile,a
R11521 T17153 T17151 arg1Of profile,subsequent
R11522 T17153 T17152 arg1Of profile,cytokine
R11523 T17153 T17154 arg1Of profile,different
R11524 T17153 T17161 arg1Of profile,and
R11525 T17154 T17155 arg1Of different,from
R11526 T17154 T17159 arg1Of different,from
R11527 T17155 T17157 arg1Of from,and
R11528 T17156 T17155 arg2Of LPS,from
R11529 T17159 T17157 arg2Of from,and
R11530 T17159 T17158 arg1Of from,also
R11531 T17160 T17159 arg2Of TSST-1,from
R11532 T17162 T17138 arg2Of ",",demonstrated
R11533 T17162 T17139 arg1Of ",",that
R11534 T17165 T17162 arg2Of switched,","
R11535 T17165 T17163 arg1Of switched,moreover
R11536 T17165 T17164 arg1Of switched,","
R11537 T17169 T17165 arg2Of response,switched
R11538 T17169 T17166 arg1Of response,a
R11539 T17169 T17167 arg1Of response,pro-inflammatory
R11540 T17169 T17168 arg1Of response,TSST-1-induced
R11541 T17169 T17170 arg1Of response,to
R11542 T17174 T17170 arg2Of reaction,to
R11543 T17174 T17171 arg1Of reaction,an
R11544 T17174 T17172 arg1Of reaction,IL-1RA-mediated
R11545 T17174 T17173 arg1Of reaction,anti-inflammatory
R11546 T17176 T17175 arg1Of results,Our
R11547 T17176 T17178 arg1Of results,generated
R11548 T17178 T17177 arg1Of generated,also
R11549 T17178 T17181 arg1Of generated,into
R11550 T17180 T17178 arg2Of insights,generated
R11551 T17180 T17179 arg1Of insights,new
R11552 T17184 T17183 arg1Of complex,very
R11553 T17185 T17181 arg2Of interplay,into
R11554 T17185 T17182 arg1Of interplay,a
R11555 T17185 T17184 arg1Of interplay,complex
R11556 T17185 T17186 arg1Of interplay,of
R11557 T17188 T17186 arg2Of factor,of
R11558 T17188 T17187 arg1Of factor,transcription
R11559 T17188 T17189 arg1Of factor,binding
R11560 T17188 T17197 arg1Of factor,in
R11561 T17188 T17205 arg1Of factor,","
R11562 T17188 T17206 arg1Of factor,which
R11563 T17188 T17207 arg1Of factor,can
R11564 T17188 T17208 arg1Of factor,be
R11565 T17188 T17209 arg2Of factor,regulated
R11566 T17189 T17190 arg1Of binding,to
R11567 T17192 T17193 arg1Of known,and
R11568 T17195 T17193 arg2Of identified,and
R11569 T17195 T17194 arg1Of identified,newly
R11570 T17196 T17190 arg2Of sites,to
R11571 T17196 T17191 arg1Of sites,various
R11572 T17196 T17192 arg1Of sites,known
R11573 T17196 T17195 arg1Of sites,identified
R11574 T17200 T17197 arg2Of promoter,in
R11575 T17200 T17198 arg1Of promoter,the
R11576 T17200 T17199 arg1Of promoter,IL-1RA
R11577 T17200 T17201 arg1Of promoter,(
R11578 T17202 T17201 arg2Of Fig.,(
R11579 T17202 T17203 arg1Of Fig.,8
R11580 T17204 T17201 arg3Of ),(
R11581 T17209 T17207 arg2Of regulated,can
R11582 T17209 T17208 arg2Of regulated,be
R11583 T17209 T17210 arg1Of regulated,differentially
R11584 T17214 T17209 arg1Of carbohydrate,regulated
R11585 T17214 T17211 arg2Of carbohydrate,by
R11586 T17214 T17212 arg1Of carbohydrate,a
R11587 T17214 T17213 arg1Of carbohydrate,fungal
R11588 T17215 T17216 arg1Of Together,with
R11589 T17219 T17218 arg1Of vivo,in
R11590 T17220 T17216 arg2Of studies,with
R11591 T17220 T17217 arg1Of studies,the
R11592 T17220 T17219 arg1Of studies,vivo
R11593 T17220 T17221 arg1Of studies,[
R11594 T17222 T17221 arg2Of "22,37",[
R11595 T17223 T17221 arg3Of ],[
R11596 T17226 T17225 arg1Of findings,our
R11597 T17226 T17227 arg1Of findings,might
R11598 T17226 T17228 arg1Of findings,support
R11599 T17228 T17215 arg1Of support,Together
R11600 T17228 T17224 arg1Of support,","
R11601 T17228 T17227 arg2Of support,might
R11602 T17230 T17228 arg2Of concept,support
R11603 T17230 T17229 arg1Of concept,the
R11604 T17230 T17231 arg1Of concept,of
R11605 T17233 T17231 arg2Of effects,of
R11606 T17233 T17232 arg1Of effects,protective
R11607 T17233 T17234 arg2Of effects,mediated
R11608 T17237 T17234 arg1Of phosphate,mediated
R11609 T17237 T17235 arg2Of phosphate,by
R11610 T17237 T17236 arg1Of phosphate,glucan
R11611 T17237 T17238 arg1Of phosphate,in
R11612 T17240 T17238 arg2Of conditions,in
R11613 T17240 T17239 arg1Of conditions,pro-inflammatory
R11614 T17240 T17241 arg1Of conditions,","
R11615 T17240 T17243 arg1Of conditions,with
R11616 T17243 T17242 arg1Of with,especially
R11617 T17247 T17243 arg2Of ratio,with
R11618 T17247 T17244 arg1Of ratio,a
R11619 T17247 T17245 arg2Of ratio,dysregulated
R11620 T17247 T17246 arg1Of ratio,IL-1β/IL-1RA
R11621 T17247 T17248 arg1Of ratio,[
R11622 T17249 T17248 arg2Of "52,53",[
R11623 T17250 T17248 arg3Of ],[
R11765 T17471 T17469 arg1Of β-1→3-D-glucan,soluble
R11766 T17471 T17470 arg2Of β-1→3-D-glucan,phosphorylated
R11767 T17471 T17472 arg1Of β-1→3-D-glucan,(
R11768 T17471 T17475 arg1Of β-1→3-D-glucan,was
R11769 T17471 T17476 arg2Of β-1→3-D-glucan,prepared
R11770 T17473 T17472 arg2Of GP,(
R11771 T17474 T17472 arg3Of ),(
R11772 T17476 T17468 arg1Of prepared,Water
R11773 T17476 T17475 arg2Of prepared,was
R11774 T17476 T17477 arg1Of prepared,as
R11775 T17478 T17477 arg2Of done,as
R11776 T17478 T17479 arg1Of done,before
R11777 T17481 T17479 arg2Of 20,before
R11778 T17481 T17480 arg2Of 20,[
R11779 T17482 T17480 arg3Of ],[
R11780 T17485 T17483 arg1Of characteristics,The
R11781 T17485 T17484 arg1Of characteristics,physicochemical
R11782 T17485 T17486 arg1Of characteristics,of
R11783 T17485 T17488 arg1Of characteristics,were
R11784 T17485 T17489 arg2Of characteristics,determined
R11785 T17487 T17486 arg2Of GP,of
R11786 T17489 T17488 arg2Of determined,were
R11787 T17489 T17490 arg1Of determined,as
R11788 T17489 T17493 arg1Of determined,[
R11789 T17491 T17490 arg2Of reported,as
R11790 T17491 T17492 arg1Of reported,previously
R11791 T17494 T17493 arg2Of "20,26",[
R11792 T17495 T17493 arg3Of ],[
R11793 T17496 T17497 arg1Of GP,was
R11794 T17496 T17498 arg2Of GP,dissolved
R11795 T17496 T17509 arg2Of GP,screened
R11796 T17498 T17499 arg1Of dissolved,in
R11797 T17498 T17508 arg1Of dissolved,and
R11798 T17501 T17499 arg2Of media,in
R11799 T17501 T17500 arg1Of media,aqueous
R11800 T17501 T17502 arg1Of media,","
R11801 T17503 T17502 arg2Of filter-sterilized,","
R11802 T17503 T17504 arg1Of filter-sterilized,(
R11803 T17506 T17504 arg2Of μm,(
R11804 T17506 T17505 arg1Of μm,0.2
R11805 T17507 T17504 arg3Of ),(
R11806 T17508 T17497 arg2Of and,was
R11807 T17509 T17508 arg2Of screened,and
R11808 T17509 T17510 arg1Of screened,for
R11809 T17509 T17513 arg1Of screened,with
R11810 T17512 T17510 arg2Of contamination,for
R11811 T17512 T17511 arg1Of contamination,endotoxin
R11812 T17516 T17513 arg2Of assay,with
R11813 T17516 T17514 arg1Of assay,the
R11814 T17516 T17515 arg1Of assay,Endospecy
R11815 T17516 T17517 arg1Of assay,(
R11816 T17516 T17524 arg1Of assay,","
R11817 T17516 T17525 arg1Of assay,which
R11818 T17516 T17526 arg1Of assay,is
R11819 T17516 T17527 arg1Of assay,specific
R11820 T17516 T17531 arg1Of assay,does
R11821 T17516 T17533 arg1Of assay,respond
R11822 T17518 T17519 arg1Of Seigakaku,","
R11823 T17519 T17517 arg2Of ",",(
R11824 T17519 T17521 arg1Of ",",","
R11825 T17520 T17519 arg2Of Tokyo,","
R11826 T17522 T17521 arg2Of Japan,","
R11827 T17523 T17517 arg3Of ),(
R11828 T17526 T17530 arg1Of is,but
R11829 T17527 T17526 arg2Of specific,is
R11830 T17527 T17528 arg1Of specific,for
R11831 T17529 T17528 arg2Of endotoxin,for
R11832 T17533 T17530 arg2Of respond,but
R11833 T17533 T17531 arg2Of respond,does
R11834 T17533 T17532 arg1Of respond,not
R11835 T17533 T17534 arg1Of respond,to
R11836 T17535 T17534 arg2Of β-1→3-D-glucans,to
R11913 T17624 T17625 arg1Of Isolation,of
R11914 T17627 T17625 arg2Of PBMC,of
R11915 T17627 T17626 arg1Of PBMC,human
R11916 T17629 T17628 arg1Of coats,Buffy
R11917 T17629 T17630 arg1Of coats,were
R11918 T17629 T17631 arg2Of coats,obtained
R11919 T17631 T17630 arg2Of obtained,were
R11920 T17631 T17632 arg1Of obtained,from
R11921 T17631 T17643 arg1Of obtained,with
R11922 T17632 T17642 arg1Of from,and
R11923 T17635 T17632 arg2Of donors,from
R11924 T17635 T17633 arg1Of donors,healthy
R11925 T17635 T17634 arg1Of donors,blood
R11926 T17635 T17636 arg1Of donors,in
R11927 T17637 T17636 arg2Of compliance,in
R11928 T17637 T17638 arg1Of compliance,with
R11929 T17641 T17638 arg2Of declaration,with
R11930 T17641 T17639 arg1Of declaration,the
R11931 T17641 T17640 arg1Of declaration,Helsinki
R11932 T17643 T17642 arg2Of with,and
R11933 T17645 T17643 arg2Of approval,with
R11934 T17645 T17644 arg1Of approval,the
R11935 T17645 T17646 arg1Of approval,of
R11936 T17649 T17646 arg2Of committee,of
R11937 T17649 T17647 arg1Of committee,the
R11938 T17649 T17648 arg1Of committee,ethics
R11939 T17649 T17650 arg1Of committee,of
R11940 T17649 T17658 modOf committee,were
R11941 T17652 T17650 arg2Of University,of
R11942 T17652 T17651 arg1Of University,the
R11943 T17652 T17653 arg1Of University,of
R11944 T17654 T17653 arg2Of Luebeck.,of
R11945 T17657 T17655 arg1Of coats,The
R11946 T17657 T17656 arg1Of coats,buffy
R11947 T17657 T17658 arg1Of coats,were
R11948 T17657 T17659 arg2Of coats,separated
R11949 T17659 T17658 arg2Of separated,were
R11950 T17659 T17660 arg1Of separated,over
R11951 T17659 T17671 arg1Of separated,[
R11952 T17662 T17663 arg1Of Ficoll-Hypaque,(
R11953 T17664 T17665 arg1Of Biochrom,","
R11954 T17665 T17663 arg2Of ",",(
R11955 T17665 T17667 arg1Of ",",","
R11956 T17666 T17665 arg2Of Berlin,","
R11957 T17668 T17667 arg2Of Germany,","
R11958 T17669 T17663 arg3Of ),(
R11959 T17670 T17660 arg2Of gradient,over
R11960 T17670 T17661 arg1Of gradient,a
R11961 T17670 T17662 arg1Of gradient,Ficoll-Hypaque
R11962 T17672 T17671 arg2Of "54,55",[
R11963 T17673 T17671 arg3Of ],[
R11964 T17675 T17674 arg2Of isolation,Following
R11965 T17677 T17678 arg1Of PBMC,were
R11966 T17677 T17679 arg2Of PBMC,cultured
R11967 T17679 T17674 arg1Of cultured,Following
R11968 T17679 T17676 arg1Of cultured,","
R11969 T17679 T17678 arg2Of cultured,were
R11970 T17679 T17680 arg1Of cultured,at
R11971 T17683 T17680 arg2Of concentration,at
R11972 T17683 T17681 arg1Of concentration,a
R11973 T17683 T17682 arg1Of concentration,final
R11974 T17683 T17684 arg1Of concentration,of
R11975 T17685 T17684 arg2Of 3,of
R11976 T17688 T17687 arg1Of cells/ml,106
R11977 T17688 T17689 arg1Of cells/ml,(
R11978 T17688 T17694 arg1Of cells/ml,or
R11979 T17690 T17689 arg2Of for,(
R11980 T17692 T17690 arg2Of measurements,for
R11981 T17692 T17691 arg1Of measurements,ELISA
R11982 T17693 T17689 arg3Of ),(
R11983 T17694 T17703 arg1Of or,or
R11984 T17695 T17696 arg1Of 5,×
R11985 T17696 T17694 arg2Of ×,or
R11986 T17696 T17698 arg1Of ×,(
R11987 T17697 T17696 arg2Of 106/ml,×
R11988 T17699 T17698 arg2Of for,(
R11989 T17701 T17699 arg2Of shifts,for
R11990 T17701 T17700 arg1Of shifts,gel
R11991 T17702 T17698 arg3Of ),(
R11992 T17703 T17680 arg3Of or,at
R11993 T17703 T17686 arg1Of or,×
R11994 T17704 T17705 arg1Of 1,×
R11995 T17706 T17705 arg2Of 106,×
R11996 T17707 T17704 arg1Of cells/ml,1
R11997 T17707 T17706 arg1Of cells/ml,106
R11998 T17707 T17708 arg1Of cells/ml,(
R11999 T17707 T17713 arg1Of cells/ml,in
R12000 T17707 T17726 arg1Of cells/ml,","
R12001 T17707 T17727 arg1Of cells/ml,containing
R12002 T17707 T17734 arg1Of cells/ml,(
R12003 T17707 T17745 arg1Of cells/ml,","
R12004 T17709 T17708 arg2Of for,(
R12005 T17711 T17709 arg2Of cytometry,for
R12006 T17711 T17710 arg1Of cytometry,flow
R12007 T17712 T17708 arg3Of ),(
R12008 T17716 T17713 arg2Of medium,in
R12009 T17716 T17714 arg1Of medium,RPMI
R12010 T17716 T17715 arg1Of medium,1640
R12011 T17716 T17717 arg1Of medium,(
R12012 T17718 T17719 arg1Of BioWhittaker,","
R12013 T17719 T17721 arg1Of ",",","
R12014 T17720 T17719 arg2Of Heidelberg,","
R12015 T17721 T17717 arg2Of ",",(
R12016 T17721 T17723 arg1Of ",",","
R12017 T17721 T17724 arg1Of ",",LPS-free
R12018 T17722 T17721 arg2Of Germany,","
R12019 T17725 T17717 arg3Of ),(
R12020 T17728 T17729 arg1Of 10,%
R12021 T17733 T17727 arg2Of serum,containing
R12022 T17733 T17728 arg1Of serum,10
R12023 T17733 T17730 arg1Of serum,heat-inactivated
R12024 T17733 T17731 arg1Of serum,fetal
R12025 T17733 T17732 arg1Of serum,calf
R12026 T17735 T17736 arg1Of FCS,","
R12027 T17735 T17738 arg1Of FCS,","
R12028 T17735 T17740 arg1Of FCS,","
R12029 T17737 T17736 arg2Of low-LPS,","
R12030 T17739 T17738 arg2Of Invitrogen,","
R12031 T17740 T17734 arg2Of ",",(
R12032 T17741 T17740 arg2Of Karlsruhe,","
R12033 T17741 T17742 arg1Of Karlsruhe,","
R12034 T17743 T17742 arg2Of Germany,","
R12035 T17744 T17734 arg3Of ),(
R12036 T17745 T17753 arg1Of ",",","
R12037 T17746 T17747 arg1Of 1,%
R12038 T17748 T17745 arg2Of penicillin,","
R12039 T17748 T17746 arg1Of penicillin,1
R12040 T17748 T17749 arg1Of penicillin,(
R12041 T17751 T17749 arg2Of U/ml,(
R12042 T17751 T17750 arg1Of U/ml,10000
R12043 T17752 T17749 arg3Of ),(
R12044 T17753 T17762 arg1Of ",",and
R12045 T17754 T17755 arg1Of 1,%
R12046 T17756 T17753 arg2Of streptomycin,","
R12047 T17756 T17754 arg1Of streptomycin,1
R12048 T17756 T17757 arg1Of streptomycin,(
R12049 T17759 T17757 arg2Of μg/ml,(
R12050 T17759 T17758 arg1Of μg/ml,10000
R12051 T17760 T17757 arg3Of ),(
R12052 T17762 T17703 arg2Of and,or
R12053 T17762 T17761 arg1Of and,","
R12054 T17765 T17766 arg1Of 200,mM
R12055 T17767 T17762 arg2Of L-glutamine,and
R12056 T17767 T17763 arg1Of L-glutamine,1
R12057 T17767 T17764 arg1Of L-glutamine,%
R12058 T17767 T17765 arg1Of L-glutamine,200
R12059 T17767 T17768 arg1Of L-glutamine,(
R12060 T17769 T17768 arg2Of BioWhittaker,(
R12061 T17770 T17768 arg3Of ),(
R12214 T17956 T17955 arg1Of conditions,Stimulation
R12215 T17958 T17957 arg2Of induction,For
R12216 T17958 T17959 arg1Of induction,of
R12217 T17961 T17960 arg1Of factors,transcription
R12218 T17961 T17962 arg1Of factors,and
R12219 T17962 T17959 arg2Of and,of
R12220 T17963 T17962 arg2Of cytokines,and
R12221 T17965 T17966 arg1Of PBMC,were
R12222 T17965 T17967 arg2Of PBMC,cultured
R12223 T17967 T17957 arg1Of cultured,For
R12224 T17967 T17964 arg1Of cultured,","
R12225 T17967 T17966 arg2Of cultured,were
R12226 T17967 T17968 arg1Of cultured,in
R12227 T17967 T17980 arg1Of cultured,(
R12228 T17970 T17968 arg2Of volume,in
R12229 T17970 T17969 arg1Of volume,a
R12230 T17970 T17971 arg1Of volume,of
R12231 T17970 T17974 arg1Of volume,in
R12232 T17973 T17971 arg2Of ml,of
R12233 T17973 T17972 arg1Of ml,4
R12234 T17979 T17974 arg2Of plates,in
R12235 T17979 T17975 arg1Of plates,sterile
R12236 T17979 T17976 arg1Of plates,pyrogen-free
R12237 T17979 T17977 arg1Of plates,6-well
R12238 T17979 T17978 arg1Of plates,culture
R12239 T17981 T17982 arg1Of Falcon,","
R12240 T17982 T17980 arg2Of ",",(
R12241 T17982 T17984 arg1Of ",",","
R12242 T17983 T17982 arg2Of Heidelberg,","
R12243 T17985 T17984 arg2Of Germany,","
R12244 T17986 T17980 arg3Of ),(
R12245 T17987 T17988 arg1Of Cultures,were
R12246 T17987 T17989 arg2Of Cultures,stimulated
R12247 T17989 T17988 arg2Of stimulated,were
R12248 T17989 T17990 arg1Of stimulated,for
R12249 T17989 T17997 arg1Of stimulated,from
R12250 T17989 T18000 arg1Of stimulated,to
R12251 T17989 T18017 arg1Of stimulated,with
R12252 T17989 T18033 arg1Of stimulated,with
R12253 T17989 T18038 arg1Of stimulated,LPS
R12254 T17990 T17996 arg1Of for,or
R12255 T17992 T17990 arg2Of h,for
R12256 T17992 T17991 arg1Of h,1
R12257 T17992 T17993 arg1Of h,(
R12258 T17994 T17993 arg2Of EMSA,(
R12259 T17995 T17993 arg3Of ),(
R12260 T17997 T17996 arg2Of from,or
R12261 T17999 T17997 arg2Of h,from
R12262 T17999 T17998 arg1Of h,0
R12263 T18002 T18000 arg2Of h,to
R12264 T18002 T18001 arg1Of h,48
R12265 T18002 T18003 arg1Of h,(
R12266 T18002 T18006 arg1Of h,with
R12267 T18002 T18016 arg1Of h,","
R12268 T18004 T18003 arg2Of ELISA,(
R12269 T18005 T18003 arg3Of ),(
R12270 T18007 T18008 arg1Of 1,or
R12271 T18009 T18008 arg2Of 100,or
R12272 T18010 T18006 arg2Of μg,with
R12273 T18010 T18007 arg1Of μg,1
R12274 T18010 T18009 arg1Of μg,100
R12275 T18010 T18011 arg1Of μg,per
R12276 T18013 T18011 arg2Of cells,per
R12277 T18013 T18012 arg1Of cells,106
R12278 T18013 T18014 arg1Of cells,of
R12279 T18015 T18014 arg2Of GP,of
R12280 T18017 T18032 arg1Of with,or
R12281 T18020 T18018 arg1Of cells,250
R12282 T18020 T18019 arg1Of cells,ng/106
R12283 T18021 T18017 arg2Of TSST-1,with
R12284 T18021 T18020 arg1Of TSST-1,cells
R12285 T18021 T18022 arg1Of TSST-1,(
R12286 T18024 T18022 arg2Of Technologies,(
R12287 T18024 T18023 arg1Of Technologies,Toxin
R12288 T18024 T18025 arg1Of Technologies,","
R12289 T18024 T18029 arg1Of Technologies,","
R12290 T18026 T18027 arg1Of Sarasota,","
R12291 T18027 T18025 arg2Of ",",","
R12292 T18028 T18027 arg2Of FL,","
R12293 T18030 T18029 arg2Of USA,","
R12294 T18031 T18022 arg3Of ),(
R12295 T18033 T18032 arg2Of with,or
R12296 T18036 T18033 arg2Of cells,with
R12297 T18036 T18034 arg1Of cells,250
R12298 T18036 T18035 arg1Of cells,ng/106
R12299 T18038 T18037 arg1Of LPS,wild-type
R12300 T18038 T18039 arg1Of LPS,from
R12301 T18038 T18044 arg1Of LPS,:
R12302 T18042 T18039 arg2Of serotype,from
R12303 T18042 T18040 arg1Of serotype,Escherichia
R12304 T18042 T18041 arg1Of serotype,coli
R12305 T18042 T18043 arg1Of serotype,0111
R12306 T18045 T18044 arg2Of B4,:
R12307 T18045 T18046 arg1Of B4,(
R12308 T18047 T18048 arg1Of Sigma,","
R12309 T18048 T18046 arg2Of ",",(
R12310 T18048 T18050 arg1Of ",",","
R12311 T18049 T18048 arg2Of Munich,","
R12312 T18051 T18050 arg2Of Germany,","
R12313 T18052 T18046 arg3Of ),(
R12314 T18055 T18053 arg2Of experiments,In
R12315 T18055 T18054 arg1Of experiments,costimulatory
R12316 T18057 T18058 arg1Of PBMC,were
R12317 T18057 T18059 arg2Of PBMC,supplemented
R12318 T18059 T18053 arg1Of supplemented,In
R12319 T18059 T18056 arg1Of supplemented,","
R12320 T18059 T18058 arg2Of supplemented,were
R12321 T18059 T18060 arg1Of supplemented,simultaneously
R12322 T18059 T18061 arg1Of supplemented,with
R12323 T18059 T18069 arg1Of supplemented,with
R12324 T18061 T18068 arg1Of with,or
R12325 T18063 T18061 arg2Of combination,with
R12326 T18063 T18062 arg1Of combination,a
R12327 T18063 T18064 arg1Of combination,of
R12328 T18065 T18066 arg1Of GP,and
R12329 T18066 T18064 arg2Of and,of
R12330 T18067 T18066 arg2Of TSST-1,and
R12331 T18069 T18068 arg2Of with,or
R12332 T18071 T18069 arg2Of combination,with
R12333 T18071 T18070 arg1Of combination,a
R12334 T18071 T18072 arg1Of combination,of
R12335 T18073 T18074 arg1Of GP,and
R12336 T18074 T18072 arg2Of and,of
R12337 T18075 T18074 arg2Of LPS,and
R12470 T18303 T18304 arg1Of Oligonucleotides,(
R12471 T18303 T18307 arg1Of Oligonucleotides,and
R12472 T18305 T18304 arg2Of Oligos,(
R12473 T18306 T18304 arg3Of ),(
R12474 T18308 T18307 arg2Of 5'-32-P-Labeling,and
R12475 T18313 T18312 arg2Of ds,(
R12476 T18314 T18312 arg3Of ),(
R12477 T18315 T18309 arg1Of oligonucleotides,The
R12478 T18315 T18310 arg1Of oligonucleotides,complementary
R12479 T18315 T18311 arg1Of oligonucleotides,double-stranded
R12480 T18315 T18312 arg1Of oligonucleotides,(
R12481 T18315 T18316 arg1Of oligonucleotides,(
R12482 T18315 T18319 arg1Of oligonucleotides,from
R12483 T18315 T18329 arg1Of oligonucleotides,were
R12484 T18315 T18330 arg2Of oligonucleotides,synthesised
R12485 T18315 T18354 arg1Of oligonucleotides,32P-labeled
R12486 T18317 T18316 arg2Of oligos,(
R12487 T18318 T18316 arg3Of ),(
R12488 T18321 T18322 arg1Of TNFα,","
R12489 T18322 T18324 arg1Of ",",","
R12490 T18323 T18322 arg2Of IL-8,","
R12491 T18324 T18326 arg1Of ",",and
R12492 T18325 T18324 arg2Of IFNγ,","
R12493 T18327 T18326 arg2Of IL-6,and
R12494 T18328 T18319 arg2Of promoters,from
R12495 T18328 T18320 arg1Of promoters,the
R12496 T18328 T18321 arg1Of promoters,TNFα
R12497 T18328 T18323 arg1Of promoters,IL-8
R12498 T18328 T18325 arg1Of promoters,IFNγ
R12499 T18328 T18327 arg1Of promoters,IL-6
R12500 T18330 T18331 arg1Of synthesised,from
R12501 T18330 T18353 arg1Of synthesised,and
R12502 T18333 T18332 arg1Of stranded,single
R12503 T18333 T18334 arg1Of stranded,(
R12504 T18335 T18334 arg2Of ss,(
R12505 T18336 T18334 arg3Of ),(
R12506 T18337 T18331 arg2Of oligos,from
R12507 T18337 T18333 arg1Of oligos,stranded
R12508 T18337 T18338 arg1Of oligos,(
R12509 T18337 T18344 arg1Of oligos,","
R12510 T18337 T18345 arg1Of oligos,(
R12511 T18339 T18338 arg2Of illustrated,(
R12512 T18339 T18340 arg1Of illustrated,in
R12513 T18342 T18340 arg2Of 1,in
R12514 T18342 T18341 arg1Of 1,Table
R12515 T18343 T18338 arg3Of ),(
R12516 T18347 T18345 arg2Of Molbiol,(
R12517 T18347 T18346 arg1Of Molbiol,TIB
R12518 T18347 T18348 arg1Of Molbiol,","
R12519 T18349 T18348 arg2Of Berlin,","
R12520 T18349 T18350 arg1Of Berlin,","
R12521 T18351 T18350 arg2Of Germany,","
R12522 T18352 T18345 arg3Of ),(
R12523 T18353 T18329 arg2Of and,were
R12524 T18354 T18353 arg2Of 32P-labeled,and
R12525 T18354 T18355 arg1Of 32P-labeled,with
R12526 T18356 T18355 arg2Of 5'γ-P-ATP,with
R12527 T18356 T18357 arg1Of 5'γ-P-ATP,(
R12528 T18356 T18367 arg1Of 5'γ-P-ATP,using
R12529 T18359 T18357 arg2Of Ci/mmol,(
R12530 T18359 T18358 arg1Of Ci/mmol,"3,000"
R12531 T18359 T18360 arg1Of Ci/mmol,","
R12532 T18359 T18364 arg1Of Ci/mmol,","
R12533 T18361 T18362 arg1Of Amersham,","
R12534 T18362 T18360 arg2Of ",",","
R12535 T18363 T18362 arg2Of Braunschweig,","
R12536 T18365 T18364 arg2Of Germany,","
R12537 T18366 T18357 arg3Of ),(
R12538 T18367 T18382 arg1Of using,according
R12539 T18370 T18367 arg2Of Kit,using
R12540 T18370 T18368 arg1Of Kit,the
R12541 T18370 T18369 arg1Of Kit,Ready-To-Go-Polynucleotide-Kinase
R12542 T18370 T18371 arg1Of Kit,(
R12543 T18373 T18372 arg1Of Kit,PNK
R12544 T18373 T18374 arg1Of Kit,","
R12545 T18373 T18377 arg1Of Kit,","
R12546 T18376 T18374 arg2Of LKB,","
R12547 T18376 T18375 arg1Of LKB,Pharmacia
R12548 T18377 T18371 arg2Of ",",(
R12549 T18378 T18377 arg2Of Freiburg,","
R12550 T18378 T18379 arg1Of Freiburg,","
R12551 T18380 T18379 arg2Of Germany,","
R12552 T18381 T18371 arg3Of ),(
R12553 T18383 T18382 arg2Of to,according
R12554 T18385 T18384 arg1Of manufacturer,the
R12555 T18385 T18386 arg2Of manufacturer,'s
R12556 T18387 T18383 arg2Of instructions,to
R12557 T18387 T18386 arg1Of instructions,'s
R12558 T18389 T18388 arg1Of test,To
R12559 T18392 T18389 arg2Of specificity,test
R12560 T18392 T18390 arg1Of specificity,the
R12561 T18392 T18391 arg1Of specificity,binding
R12562 T18392 T18393 arg1Of specificity,of
R12563 T18395 T18393 arg2Of oligos,of
R12564 T18395 T18394 arg1Of oligos,the
R12565 T18398 T18397 arg2Of oligos,mutated
R12566 T18398 T18399 arg1Of oligos,were
R12567 T18398 T18400 arg2Of oligos,used
R12568 T18400 T18388 modOf used,To
R12569 T18400 T18396 arg1Of used,","
R12570 T18400 T18399 arg2Of used,were
R12571 T18400 T18401 arg1Of used,as
R12572 T18404 T18401 arg2Of control,as
R12573 T18404 T18402 arg1Of control,an
R12574 T18404 T18403 arg1Of control,additional
R12575 T18405 T18406 arg1Of Mutations,in
R12576 T18405 T18418 arg1Of Mutations,in
R12577 T18405 T18427 arg1Of Mutations,[
R12578 T18405 T18430 arg1Of Mutations,have
R12579 T18405 T18431 arg1Of Mutations,been
R12580 T18405 T18432 arg2Of Mutations,reported
R12581 T18405 T18434 arg1Of Mutations,interfere
R12582 T18406 T18417 arg1Of in,and
R12583 T18409 T18406 arg2Of site,in
R12584 T18409 T18407 arg1Of site,the
R12585 T18409 T18408 arg1Of site,P2
R12586 T18409 T18410 arg1Of site,of
R12587 T18413 T18410 arg2Of promoter,of
R12588 T18413 T18411 arg1Of promoter,the
R12589 T18413 T18412 arg1Of promoter,IFNγ
R12590 T18413 T18414 arg1Of promoter,[
R12591 T18415 T18414 arg2Of 29,[
R12592 T18416 T18414 arg3Of ],[
R12593 T18418 T18417 arg2Of in,and
R12594 T18422 T18418 arg2Of sequence,in
R12595 T18422 T18419 arg1Of sequence,the
R12596 T18422 T18420 arg1Of sequence,κ
R12597 T18422 T18421 arg1Of sequence,consensus
R12598 T18422 T18423 arg1Of sequence,of
R12599 T18426 T18423 arg2Of promoter,of
R12600 T18426 T18424 arg1Of promoter,the
R12601 T18426 T18425 arg1Of promoter,TNFα
R12602 T18428 T18427 arg2Of 55,[
R12603 T18429 T18427 arg3Of ],[
R12604 T18432 T18430 arg2Of reported,have
R12605 T18432 T18431 arg2Of reported,been
R12606 T18434 T18432 arg3Of interfere,reported
R12607 T18434 T18433 arg1Of interfere,to
R12608 T18434 T18435 arg1Of interfere,with
R12609 T18436 T18435 arg2Of sequences,with
R12610 T18436 T18437 arg1Of sequences,","
R12611 T18436 T18438 arg1Of sequences,which
R12612 T18436 T18439 arg1Of sequences,seem
R12613 T18436 T18441 arg1Of sequences,be
R12614 T18436 T18442 arg1Of sequences,crucial
R12615 T18441 T18439 arg2Of be,seem
R12616 T18441 T18440 arg1Of be,to
R12617 T18441 T18451 arg1Of be,","
R12618 T18441 T18452 arg1Of be,respectively
R12619 T18442 T18441 arg2Of crucial,be
R12620 T18442 T18443 arg1Of crucial,for
R12621 T18445 T18443 arg2Of binding,for
R12622 T18445 T18444 arg1Of binding,the
R12623 T18445 T18446 arg1Of binding,of
R12624 T18447 T18448 arg1Of NFAT,and
R12625 T18449 T18448 arg2Of NFκB,and
R12626 T18450 T18446 arg2Of proteins,of
R12627 T18450 T18447 arg1Of proteins,NFAT
R12628 T18450 T18449 arg1Of proteins,NFκB
R12629 T18457 T18455 arg1Of oligos,the
R12630 T18457 T18456 arg1Of oligos,ds
R12631 T18457 T18458 arg1Of oligos,were
R12632 T18457 T18459 arg2Of oligos,purified
R12633 T18457 T18463 arg1Of oligos,using
R12634 T18459 T18453 arg1Of purified,Afterwards
R12635 T18459 T18454 arg1Of purified,","
R12636 T18459 T18458 arg2Of purified,were
R12637 T18459 T18460 arg1Of purified,via
R12638 T18459 T18463 modOf purified,using
R12639 T18462 T18460 arg2Of filtration,via
R12640 T18462 T18461 arg1Of filtration,gel
R12641 T18468 T18464 arg1Of Columns,Probe
R12642 T18468 T18465 arg1Of Columns,Quant
R12643 T18468 T18466 arg1Of Columns,G-50
R12644 T18468 T18467 arg1Of Columns,Micro
R12645 T18468 T18469 arg1Of Columns,(
R12646 T18468 T18472 arg1Of Columns,according
R12647 T18470 T18469 arg2Of Pharmacia,(
R12648 T18471 T18469 arg3Of ),(
R12649 T18473 T18472 arg2Of to,according
R12650 T18475 T18474 arg1Of manufacturer,the
R12651 T18475 T18476 arg2Of manufacturer,'s
R12652 T18476 T18473 arg2Of 's,to
R12653 T18477 T18463 arg2Of instructions,using
R12654 T18477 T18468 arg1Of instructions,Columns
R12866 T18814 T18815 arg1Of Preparation,of
R12867 T18817 T18816 arg1Of extracts,nuclear
R12868 T18817 T18818 arg1Of extracts,and
R12869 T18818 T18815 arg2Of and,of
R12870 T18822 T18818 arg2Of assays,and
R12871 T18822 T18819 arg1Of assays,electrophoretic
R12872 T18822 T18820 arg1Of assays,mobility
R12873 T18822 T18821 arg1Of assays,shift
R12874 T18822 T18823 arg1Of assays,(
R12875 T18824 T18823 arg2Of EMSA,(
R12876 T18825 T18823 arg3Of ),(
R12877 T18827 T18826 arg1Of extracts,Nuclear
R12878 T18827 T18828 arg1Of extracts,of
R12879 T18827 T18831 arg1Of extracts,were
R12880 T18827 T18832 arg2Of extracts,prepared
R12881 T18830 T18828 arg2Of PBMCs,of
R12882 T18830 T18829 arg2Of PBMCs,purified
R12883 T18832 T18831 arg2Of prepared,were
R12884 T18832 T18833 arg1Of prepared,according
R12885 T18834 T18833 arg2Of to,according
R12886 T18836 T18834 arg2Of technique,to
R12887 T18836 T18835 arg1Of technique,a
R12888 T18836 T18837 arg2Of technique,described
R12889 T18836 T18846 arg2Of technique,modified
R12890 T18837 T18842 arg1Of described,[
R12891 T18837 T18845 arg1Of described,and
R12892 T18839 T18837 arg1Of Trede,described
R12893 T18839 T18838 arg2Of Trede,by
R12894 T18839 T18841 arg1Of Trede,al.
R12895 T18841 T18840 arg1Of al.,et
R12896 T18843 T18842 arg2Of 27,[
R12897 T18844 T18842 arg3Of ],[
R12898 T18846 T18845 arg2Of modified,and
R12899 T18846 T18847 arg1Of modified,for
R12900 T18850 T18847 arg2Of setup,for
R12901 T18850 T18848 arg1Of setup,our
R12902 T18850 T18849 arg1Of setup,experimental
R12903 T18850 T18851 arg1Of setup,[
R12904 T18852 T18851 arg2Of 56,[
R12905 T18853 T18851 arg3Of ],[
R12906 T18855 T18854 arg1Of intensity,The
R12907 T18855 T18856 arg1Of intensity,of
R12908 T18855 T18859 arg1Of intensity,was
R12909 T18855 T18860 arg2Of intensity,normalized
R12910 T18858 T18856 arg2Of bands,of
R12911 T18858 T18857 arg2Of bands,shifted
R12912 T18860 T18859 arg2Of normalized,was
R12913 T18860 T18861 arg1Of normalized,to
R12914 T18862 T18861 arg2Of bands,to
R12915 T18862 T18863 arg1Of bands,of
R12916 T18865 T18863 arg2Of controls,of
R12917 T18865 T18864 arg1Of controls,unstimulated
R12918 T18867 T18866 arg1Of experiments,Competition
R12919 T18867 T18868 arg1Of experiments,with
R12920 T18867 T18869 arg2Of experiments,labeled
R12921 T18867 T18884 arg1Of experiments,were
R12922 T18867 T18885 arg2Of experiments,carried
R12923 T18867 T18890 arg1Of experiments,prevent
R12924 T18869 T18880 arg1Of labeled,(
R12925 T18873 T18869 arg3Of oligos,labeled
R12926 T18873 T18870 arg1Of oligos,and
R12927 T18873 T18871 arg1Of oligos,unlabeled
R12928 T18873 T18872 arg2Of oligos,mutated
R12929 T18873 T18874 arg1Of oligos,of
R12930 T18879 T18874 arg2Of sites,of
R12931 T18879 T18875 arg1Of sites,the
R12932 T18879 T18876 arg1Of sites,cytokine
R12933 T18879 T18877 arg1Of sites,promoter
R12934 T18879 T18878 arg1Of sites,binding
R12935 T18881 T18880 arg2Of see,(
R12936 T18881 T18882 arg1Of see,above
R12937 T18883 T18880 arg3Of ),(
R12938 T18885 T18884 arg2Of carried,were
R12939 T18885 T18886 arg1Of carried,out
R12940 T18885 T18887 arg1Of carried,in
R12941 T18888 T18887 arg2Of order,in
R12942 T18890 T18887 arg3Of prevent,in
R12943 T18890 T18889 arg1Of prevent,to
R12944 T18892 T18890 arg2Of binding,prevent
R12945 T18892 T18891 arg1Of binding,non-specific
R12946 T18892 T18893 arg1Of binding,to
R12947 T18895 T18893 arg2Of proteins,to
R12948 T18895 T18894 arg1Of proteins,nuclear
R12949 T18898 T18896 arg2Of experiments,For
R12950 T18898 T18897 arg1Of experiments,such
R12951 T18903 T18900 arg1Of 5–50×,an
R12952 T18903 T18901 arg1Of 5–50×,excess
R12953 T18903 T18902 arg2Of 5–50×,(
R12954 T18903 T18905 arg1Of 5–50×,of
R12955 T18903 T18908 arg1Of 5–50×,was
R12956 T18903 T18909 arg2Of 5–50×,added
R12957 T18904 T18902 arg3Of ),(
R12958 T18907 T18905 arg2Of oligos,of
R12959 T18907 T18906 arg1Of oligos,unlabeled
R12960 T18909 T18896 arg1Of added,For
R12961 T18909 T18899 arg1Of added,","
R12962 T18909 T18908 arg2Of added,was
R12963 T18909 T18910 arg1Of added,to
R12964 T18913 T18910 arg2Of extracts,to
R12965 T18913 T18911 arg1Of extracts,the
R12966 T18913 T18912 arg1Of extracts,nuclear
R12967 T18915 T18914 arg2Of specificity,For
R12968 T18915 T18916 arg1Of specificity,of
R12969 T18917 T18916 arg2Of binding,of
R12970 T18920 T18919 arg1Of assays,supershift
R12971 T18920 T18921 arg1Of assays,for
R12972 T18920 T18928 arg1Of assays,were
R12973 T18920 T18929 arg2Of assays,performed
R12974 T18922 T18921 arg2Of NFκB,for
R12975 T18922 T18923 arg1Of NFκB,with
R12976 T18927 T18923 arg2Of antibody,with
R12977 T18927 T18924 arg1Of antibody,a
R12978 T18927 T18925 arg1Of antibody,combined
R12979 T18927 T18926 arg1Of antibody,p65/50
R12980 T18929 T18914 arg1Of performed,For
R12981 T18929 T18918 arg1Of performed,","
R12982 T18929 T18928 arg2Of performed,were
R12983 T18929 T18930 arg1Of performed,(
R12984 T18931 T18930 arg2Of data,(
R12985 T18931 T18933 arg2Of data,shown
R12986 T18933 T18932 arg1Of shown,not
R12987 T18934 T18930 arg3Of ),(
R12988 T18936 T18935 arg1Of exclude,To
R12989 T18938 T18936 arg2Of reactions,exclude
R12990 T18938 T18937 arg1Of reactions,non-specific
R12991 T18943 T18936 arg1Of excess,exclude
R12992 T18943 T18940 arg1Of excess,a
R12993 T18943 T18941 arg1Of excess,30-fold
R12994 T18943 T18942 arg1Of excess,molar
R12995 T18943 T18944 arg1Of excess,of
R12996 T18943 T18947 arg1Of excess,(
R12997 T18943 T18954 arg1Of excess,was
R12998 T18943 T18955 arg2Of excess,used
R12999 T18946 T18944 arg2Of DNA,of
R13000 T18946 T18945 arg1Of DNA,Oct-1
R13001 T18949 T18947 arg2Of DNA,(
R13002 T18949 T18948 arg1Of DNA,unrelated
R13003 T18949 T18950 arg1Of DNA,","
R13004 T18949 T18951 arg1Of DNA,Table
R13005 T18951 T18952 arg1Of Table,1
R13006 T18953 T18947 arg3Of ),(
R13007 T18955 T18935 modOf used,To
R13008 T18955 T18939 arg1Of used,","
R13009 T18955 T18954 arg2Of used,was
R13010 T18955 T18956 arg1Of used,","
R13011 T18955 T18957 arg1Of used,which
R13012 T18955 T18958 arg1Of used,did
R13013 T18955 T18960 arg1Of used,compete
R13014 T18960 T18958 arg2Of compete,did
R13015 T18960 T18959 arg1Of compete,not
R13016 T18960 T18961 arg1Of compete,with
R13017 T18963 T18961 arg2Of binding,with
R13018 T18963 T18962 arg1Of binding,specific
R13198 T19288 T19285 arg2Of membrane,onto
R13199 T19288 T19286 arg1Of membrane,a
R13200 T19288 T19287 arg1Of membrane,nitrocellulose
R13201 T19288 T19289 arg1Of membrane,(
R13202 T19290 T19289 arg2Of Bio-Rad,(
R13203 T19291 T19289 arg3Of ),(
R13204 T19293 T19292 arg2Of blocking,After
R13205 T19293 T19294 arg1Of blocking,with
R13206 T19293 T19298 arg1Of blocking,(
R13207 T19297 T19294 arg2Of BSA,with
R13208 T19297 T19295 arg1Of BSA,PBS/3
R13209 T19297 T19296 arg1Of BSA,%
R13210 T19299 T19300 arg1Of Fluka,","
R13211 T19300 T19302 arg1Of ",",","
R13212 T19301 T19300 arg2Of Deisenhofen,","
R13213 T19302 T19298 arg2Of ",",(
R13214 T19303 T19302 arg2Of Germany,","
R13215 T19304 T19298 arg3Of ),(
R13216 T19307 T19293 arg1Of blot,blocking
R13217 T19307 T19306 arg1Of blot,the
R13218 T19307 T19308 arg1Of blot,was
R13219 T19307 T19309 arg2Of blot,incubated
R13220 T19309 T19292 arg1Of incubated,After
R13221 T19309 T19305 arg1Of incubated,","
R13222 T19309 T19308 arg2Of incubated,was
R13223 T19309 T19310 arg1Of incubated,overnight
R13224 T19309 T19311 arg1Of incubated,with
R13225 T19309 T19317 arg1Of incubated,:
R13226 T19314 T19311 arg2Of antibodies,with
R13227 T19314 T19312 arg1Of antibodies,the
R13228 T19314 T19313 arg1Of antibodies,primary
R13229 T19314 T19315 arg2Of antibodies,diluted
R13230 T19316 T19315 arg3Of 1,diluted
R13231 T19318 T19319 arg1Of 2000,in
R13232 T19318 T19324 arg1Of 2000,washed
R13233 T19318 T19327 arg2Of 2000,incubated
R13234 T19322 T19319 arg2Of BSA,in
R13235 T19322 T19320 arg1Of BSA,PBS/1
R13236 T19322 T19321 arg1Of BSA,%
R13237 T19324 T19325 arg1Of washed,again
R13238 T19324 T19326 arg1Of washed,and
R13239 T19326 T19317 arg2Of and,:
R13240 T19326 T19323 arg1Of and,","
R13241 T19327 T19326 arg2Of incubated,and
R13242 T19327 T19328 arg1Of incubated,with
R13243 T19333 T19328 arg2Of antibody,with
R13244 T19333 T19329 arg1Of antibody,the
R13245 T19333 T19330 arg1Of antibody,alkaline
R13246 T19333 T19331 arg1Of antibody,phosphatase-conjugated
R13247 T19333 T19332 arg1Of antibody,secondary
R13248 T19333 T19334 arg1Of antibody,(
R13249 T19335 T19336 arg1Of 1,:
R13250 T19336 T19334 arg2Of :,(
R13251 T19336 T19338 arg1Of :,in
R13252 T19337 T19336 arg2Of 500,:
R13253 T19341 T19338 arg2Of BSA,in
R13254 T19341 T19339 arg1Of BSA,PBS/1
R13255 T19341 T19340 arg1Of BSA,%
R13256 T19342 T19334 arg3Of ),(
R13257 T19344 T19343 arg1Of blot,The
R13258 T19344 T19345 arg1Of blot,was
R13259 T19344 T19346 arg2Of blot,developed
R13260 T19346 T19345 arg2Of developed,was
R13261 T19347 T19346 arg3Of using,developed
R13262 T19351 T19347 arg2Of kit,using
R13263 T19351 T19348 arg1Of kit,the
R13264 T19351 T19349 arg1Of kit,Vectastain®
R13265 T19351 T19350 arg1Of kit,staining
R13266 T19351 T19352 arg1Of kit,(
R13267 T19356 T19352 arg2Of Burlingame,(
R13268 T19356 T19353 arg1Of Burlingame,Vector
R13269 T19356 T19354 arg1Of Burlingame,Laboratories
R13270 T19356 T19355 arg1Of Burlingame,Inc.
R13271 T19356 T19357 arg1Of Burlingame,","
R13272 T19358 T19357 arg2Of CA,","
R13273 T19358 T19359 arg1Of CA,","
R13274 T19360 T19359 arg2Of USA,","
R13275 T19361 T19352 arg3Of ),(
R13522 T19802 T19801 arg1Of measurements,Cytokine
R13523 T19803 T19804 arg1Of Supernatants,of
R13524 T19803 T19807 arg1Of Supernatants,were
R13525 T19803 T19808 arg2Of Supernatants,harvested
R13526 T19803 T19830 arg1Of Supernatants,stored
R13527 T19806 T19804 arg2Of cultures,of
R13528 T19806 T19805 arg1Of cultures,cell
R13529 T19808 T19807 arg2Of harvested,were
R13530 T19808 T19829 arg1Of harvested,and
R13531 T19809 T19810 arg1Of 3,","
R13532 T19810 T19812 arg1Of ",",","
R13533 T19811 T19810 arg2Of 6,","
R13534 T19812 T19814 arg1Of ",",","
R13535 T19813 T19812 arg2Of 9,","
R13536 T19814 T19816 arg1Of ",",","
R13537 T19815 T19814 arg2Of 12,","
R13538 T19816 T19818 arg1Of ",",","
R13539 T19817 T19816 arg2Of 18,","
R13540 T19818 T19820 arg1Of ",",","
R13541 T19819 T19818 arg2Of 24,","
R13542 T19821 T19820 arg2Of 30,","
R13543 T19823 T19824 arg1Of 36,and
R13544 T19825 T19824 arg2Of 48,and
R13545 T19826 T19808 arg3Of hours,harvested
R13546 T19826 T19809 arg1Of hours,3
R13547 T19826 T19811 arg1Of hours,6
R13548 T19826 T19813 arg1Of hours,9
R13549 T19826 T19815 arg1Of hours,12
R13550 T19826 T19817 arg1Of hours,18
R13551 T19826 T19819 arg1Of hours,24
R13552 T19826 T19821 arg1Of hours,30
R13553 T19826 T19822 arg1Of hours,","
R13554 T19826 T19823 arg1Of hours,36
R13555 T19826 T19825 arg1Of hours,48
R13556 T19826 T19827 arg1Of hours,after
R13557 T19828 T19827 arg2Of stimulation,after
R13558 T19830 T19829 arg2Of stored,and
R13559 T19830 T19831 arg1Of stored,at
R13560 T19830 T19834 arg1Of stored,until
R13561 T19833 T19831 arg2Of °C,at
R13562 T19833 T19832 arg1Of °C,-80
R13563 T19835 T19836 arg1Of used,and
R13564 T19836 T19834 arg2Of and,until
R13565 T19837 T19836 arg2Of thawed,and
R13566 T19837 T19839 arg1Of thawed,once
R13567 T19839 T19838 arg1Of once,only
R13568 T19840 T19841 arg1Of IFNγ,","
R13569 T19841 T19843 arg1Of ",",","
R13570 T19842 T19841 arg2Of TNFα,","
R13571 T19843 T19845 arg1Of ",",and
R13572 T19844 T19843 arg2Of IL-1,","
R13573 T19845 T19847 arg1Of and,were
R13574 T19845 T19848 arg2Of and,determined
R13575 T19846 T19845 arg2Of IL-6,and
R13576 T19848 T19847 arg2Of determined,were
R13577 T19848 T19849 modOf determined,using
R13578 T19848 T19864 arg1Of determined,by
R13579 T19851 T19849 arg2Of ELISA,using
R13580 T19851 T19850 arg1Of ELISA,an
R13581 T19851 T19852 arg1Of ELISA,from
R13582 T19854 T19853 arg1Of Systems,Bender
R13583 T19854 T19855 arg1Of Systems,(
R13584 T19854 T19860 arg1Of Systems,","
R13585 T19856 T19855 arg2Of Vienna,(
R13586 T19856 T19857 arg1Of Vienna,","
R13587 T19856 T19858 arg1Of Vienna,Austria
R13588 T19859 T19855 arg3Of ),(
R13589 T19860 T19862 arg1Of ",",and
R13590 T19861 T19860 arg2Of IL-1RA,","
R13591 T19862 T19852 arg2Of and,from
R13592 T19863 T19862 arg2Of IL-8,and
R13593 T19866 T19867 arg1Of ELISA,from
R13594 T19866 T19878 arg1Of ELISA,and
R13595 T19871 T19867 arg2Of Systems,from
R13596 T19871 T19868 arg1Of Systems,R
R13597 T19871 T19869 arg1Of Systems,&
R13598 T19871 T19870 arg1Of Systems,D
R13599 T19871 T19872 arg1Of Systems,(
R13600 T19873 T19872 arg2Of Wiesbaden-Nordenstadt,(
R13601 T19873 T19874 arg1Of Wiesbaden-Nordenstadt,","
R13602 T19875 T19874 arg2Of Germany,","
R13603 T19876 T19872 arg3Of ),(
R13604 T19878 T19864 arg2Of and,by
R13605 T19878 T19865 arg1Of and,an
R13606 T19878 T19877 arg1Of and,","
R13607 T19879 T19878 arg2Of TGFβ,and
R13608 T19879 T19880 arg1Of TGFβ,1
R13609 T19881 T19848 arg3Of using,determined
R13610 T19881 T19884 arg1Of using,as
R13611 T19883 T19881 arg2Of ELISA,using
R13612 T19883 T19882 arg1Of ELISA,an
R13613 T19886 T19885 arg1Of described,previously
R13614 T19888 T19884 arg2Of 57,as
R13615 T19888 T19886 arg1Of 57,described
R13616 T19888 T19887 arg2Of 57,[
R13617 T19889 T19887 arg3Of ],[
R13618 T19890 T19891 arg1Of Quantification,of
R13619 T19890 T19893 arg1Of Quantification,as
R13620 T19890 T19901 arg1Of Quantification,was
R13621 T19890 T19902 arg2Of Quantification,done
R13622 T19892 T19891 arg2Of IL-2,of
R13623 T19895 T19893 arg2Of indicator,as
R13624 T19895 T19894 arg1Of indicator,an
R13625 T19895 T19896 arg1Of indicator,for
R13626 T19898 T19896 arg2Of bioactivity,for
R13627 T19898 T19897 arg1Of bioactivity,the
R13628 T19898 T19899 arg1Of bioactivity,of
R13629 T19900 T19899 arg2Of IL-1,of
R13630 T19902 T19901 arg2Of done,was
R13631 T19902 T19903 arg1Of done,as
R13632 T19905 T19904 arg1Of described,previously
R13633 T19907 T19903 arg2Of 46,as
R13634 T19907 T19905 arg1Of 46,described
R13635 T19907 T19906 arg2Of 46,[
R13636 T19908 T19906 arg3Of ],[
R13637 T19909 T19910 arg1Of Samples,were
R13638 T19909 T19911 arg2Of Samples,diluted
R13639 T19911 T19910 arg2Of diluted,were
R13640 T19911 T19912 arg1Of diluted,in
R13641 T19911 T19916 arg1Of diluted,as
R13642 T19915 T19912 arg2Of buffer,in
R13643 T19915 T19913 arg1Of buffer,the
R13644 T19915 T19914 arg1Of buffer,same
R13645 T19917 T19916 arg2Of that,as
R13646 T19917 T19918 arg2Of that,used
R13647 T19918 T19919 arg1Of used,for
R13648 T19921 T19919 arg2Of standards,for
R13649 T19921 T19920 arg1Of standards,the
R13650 T19923 T19922 arg1Of cytokines,All
R13651 T19923 T19924 arg1Of cytokines,were
R13652 T19923 T19925 arg2Of cytokines,quantified
R13653 T19925 T19924 arg2Of quantified,were
R13654 T19926 T19925 arg3Of using,quantified
R13655 T19926 T19931 arg1Of using,(
R13656 T19930 T19926 arg2Of reader,using
R13657 T19930 T19927 arg1Of reader,an
R13658 T19930 T19928 arg1Of reader,ELISA
R13659 T19930 T19929 arg1Of reader,plate
R13660 T19933 T19934 arg1Of Labotec,","
R13661 T19934 T19936 arg1Of ",",","
R13662 T19935 T19934 arg2Of Salzburg,","
R13663 T19936 T19938 arg1Of ",",or
R13664 T19937 T19936 arg2Of Austria,","
R13665 T19939 T19938 arg2Of Microplate,or
R13666 T19940 T19931 arg2Of Reader,(
R13667 T19940 T19932 arg1Of Reader,Anthos
R13668 T19940 T19933 arg1Of Reader,Labotec
R13669 T19940 T19935 arg1Of Reader,Salzburg
R13670 T19940 T19937 arg1Of Reader,Austria
R13671 T19940 T19939 arg1Of Reader,Microplate
R13672 T19940 T19941 arg1Of Reader,","
R13673 T19942 T19941 arg2Of BioRad,","
R13674 T19943 T19931 arg3Of ),(
R13675 T19945 T19944 arg1Of amounts,Cytokine
R13676 T19945 T19946 arg1Of amounts,were
R13677 T19945 T19948 arg1Of amounts,within
R13678 T19946 T19947 arg1Of were,all
R13679 T19948 T19946 arg2Of within,were
R13680 T19950 T19948 arg2Of range,within
R13681 T19950 T19949 arg1Of range,the
R13682 T19950 T19951 arg1Of range,of
R13683 T19954 T19951 arg2Of curve,of
R13684 T19954 T19952 arg1Of curve,the
R13685 T19954 T19953 arg1Of curve,standard
R13686 T19956 T19955 arg1Of stimulation,Only
R13687 T19956 T19957 arg1Of stimulation,of
R13688 T19956 T19967 arg1Of stimulation,was
R13689 T19956 T19968 arg2Of stimulation,included
R13690 T19958 T19957 arg2Of PBMC,of
R13691 T19958 T19959 arg2Of PBMC,observed
R13692 T19959 T19960 arg1Of observed,in
R13693 T19961 T19960 arg2Of donors,in
R13694 T19961 T19962 arg1Of donors,showing
R13695 T19966 T19962 arg2Of release,showing
R13696 T19966 T19963 arg1Of release,no
R13697 T19966 T19964 arg1Of release,spontaneous
R13698 T19966 T19965 arg1Of release,cytokine
R13699 T19968 T19967 arg2Of included,was
R13700 T19968 T19969 arg1Of included,in
R13701 T19971 T19969 arg2Of statistics,in
R13702 T19971 T19970 arg1Of statistics,the
R13892 T20332 T20333 arg1Of Inhibition,of
R13893 T20335 T20333 arg2Of factors,of
R13894 T20335 T20334 arg1Of factors,transcription
R13895 T20337 T20336 arg1Of inhibit,To
R13896 T20338 T20339 arg1Of translocation,and
R13897 T20339 T20337 arg2Of and,inhibit
R13898 T20340 T20339 arg2Of binding,and
R13899 T20340 T20341 arg1Of binding,of
R13900 T20340 T20344 arg1Of binding,to
R13901 T20343 T20341 arg2Of factors,of
R13902 T20343 T20342 arg1Of factors,transcription
R13903 T20347 T20344 arg2Of promoter,to
R13904 T20347 T20345 arg1Of promoter,the
R13905 T20347 T20346 arg1Of promoter,IL-1RA
R13906 T20349 T20337 arg1Of PBMC,inhibit
R13907 T20349 T20350 arg1Of PBMC,were
R13908 T20349 T20351 arg2Of PBMC,incubated
R13909 T20351 T20336 modOf incubated,To
R13910 T20351 T20348 arg1Of incubated,","
R13911 T20351 T20350 arg2Of incubated,were
R13912 T20351 T20352 arg1Of incubated,for
R13913 T20351 T20355 arg1Of incubated,with
R13914 T20351 T20361 arg1Of incubated,(
R13915 T20351 T20370 arg1Of incubated,:
R13916 T20354 T20352 arg2Of h,for
R13917 T20354 T20353 arg1Of h,1
R13918 T20356 T20355 arg2Of each,with
R13919 T20356 T20357 arg1Of each,of
R13920 T20360 T20357 arg2Of substances,of
R13921 T20360 T20358 arg1Of substances,the
R13922 T20360 T20359 arg1Of substances,following
R13923 T20362 T20363 arg1Of concentrations,were
R13924 T20362 T20364 arg2Of concentrations,based
R13925 T20364 T20361 arg2Of based,(
R13926 T20364 T20363 arg2Of based,were
R13927 T20364 T20365 arg1Of based,upon
R13928 T20366 T20367 arg1Of 50,%
R13929 T20368 T20365 arg2Of inhibition,upon
R13930 T20368 T20366 arg1Of inhibition,50
R13931 T20369 T20361 arg3Of ),(
R13932 T20372 T20371 arg1Of μg/ml,50
R13933 T20372 T20373 arg1Of μg/ml,of
R13934 T20372 T20386 arg1Of μg/ml,;
R13935 T20374 T20373 arg2Of CAPE,of
R13936 T20374 T20375 arg1Of CAPE,(
R13937 T20374 T20378 arg1Of CAPE,","
R13938 T20374 T20379 arg1Of CAPE,(
R13939 T20376 T20375 arg2Of "caffeic-3,4-dihydroxycinnamic-acid-phenyl-ester",(
R13940 T20377 T20375 arg3Of ),(
R13941 T20380 T20381 arg1Of Biomol,","
R13942 T20381 T20379 arg2Of ",",(
R13943 T20381 T20383 arg1Of ",",","
R13944 T20382 T20381 arg2Of Hamburg,","
R13945 T20384 T20383 arg2Of Germany,","
R13946 T20385 T20379 arg3Of ),(
R13947 T20387 T20388 arg1Of 400,ng/ml
R13948 T20390 T20387 arg1Of A,400
R13949 T20390 T20389 arg1Of A,cyclosporin
R13950 T20390 T20391 arg1Of A,(
R13951 T20390 T20400 arg1Of A,;
R13952 T20393 T20391 arg2Of Biosciences,(
R13953 T20393 T20392 arg1Of Biosciences,Calbiochem-Merck
R13954 T20393 T20394 arg1Of Biosciences,","
R13955 T20396 T20394 arg2Of Soden,","
R13956 T20396 T20395 arg1Of Soden,Bad
R13957 T20396 T20397 arg1Of Soden,","
R13958 T20398 T20397 arg2Of Germany,","
R13959 T20399 T20391 arg3Of ),(
R13960 T20400 T20386 arg2Of ;,;
R13961 T20400 T20409 arg1Of ;,prior
R13962 T20403 T20400 arg2Of cycloheximide,;
R13963 T20403 T20401 arg1Of cycloheximide,10
R13964 T20403 T20402 arg1Of cycloheximide,μg/ml
R13965 T20403 T20404 arg1Of cycloheximide,(
R13966 T20407 T20404 arg2Of Biotechnology,(
R13967 T20407 T20405 arg1Of Biotechnology,Santa
R13968 T20407 T20406 arg1Of Biotechnology,Cruz
R13969 T20408 T20404 arg3Of ),(
R13970 T20409 T20410 arg1Of prior,to
R13971 T20411 T20410 arg2Of incubation,to
R13972 T20411 T20412 arg1Of incubation,with
R13973 T20413 T20412 arg2Of GP,with
R13974 T20415 T20414 arg1Of shifts,Band
R13975 T20415 T20416 arg1Of shifts,were
R13976 T20415 T20417 arg2Of shifts,determined
R13977 T20417 T20416 arg2Of determined,were
R13978 T20417 T20418 arg1Of determined,after
R13979 T20419 T20420 arg1Of 1,h
R13980 T20421 T20419 arg1Of incubation,1
R13981 T20421 T20422 arg1Of incubation,with
R13982 T20421 T20424 arg1Of incubation,as
R13983 T20421 T20427 arg1Of incubation,","
R13984 T20421 T20428 arg1Of incubation,including
R13985 T20421 T20445 arg1Of incubation,and
R13986 T20423 T20422 arg2Of GP,with
R13987 T20425 T20424 arg2Of described,as
R13988 T20425 T20426 arg1Of described,before
R13989 T20430 T20428 arg2Of oligos,including
R13990 T20430 T20429 arg2Of oligos,mutated
R13991 T20430 T20431 arg1Of oligos,for
R13992 T20432 T20431 arg2Of NFIL-6,for
R13993 T20432 T20433 arg1Of NFIL-6,(
R13994 T20442 T20434 arg1Of AGT,TTA
R13995 T20442 T20435 arg1Of AGT,CAA
R13996 T20442 T20436 arg1Of AGT,CAG
R13997 T20442 T20437 arg1Of AGT,TGG
R13998 T20442 T20438 arg1Of AGT,ATT
R13999 T20442 T20439 arg1Of AGT,GCG
R14000 T20442 T20440 arg1Of AGT,ACA
R14001 T20442 T20441 arg1Of AGT,CTT
R14002 T20443 T20433 arg2Of GGG,(
R14003 T20443 T20442 arg1Of GGG,AGT
R14004 T20444 T20433 arg3Of ),(
R14005 T20445 T20418 arg2Of and,after
R14006 T20446 T20447 arg1Of NFATP2/3,(
R14007 T20457 T20447 arg2Of TCT,(
R14008 T20457 T20448 arg1Of TCT,GGC
R14009 T20457 T20449 arg1Of TCT,GCA
R14010 T20457 T20450 arg1Of TCT,GAA
R14011 T20457 T20451 arg1Of TCT,AAG
R14012 T20457 T20452 arg1Of TCT,GTA
R14013 T20457 T20453 arg1Of TCT,AAA
R14014 T20457 T20454 arg1Of TCT,TAT
R14015 T20457 T20455 arg1Of TCT,TTA
R14016 T20457 T20456 arg1Of TCT,CTA
R14017 T20458 T20447 arg3Of ),(
R14018 T20460 T20445 arg2Of sites,and
R14019 T20460 T20446 arg1Of sites,NFATP2/3
R14020 T20460 T20459 arg1Of sites,binding
R14021 T20460 T20461 arg1Of sites,within
R14022 T20464 T20461 arg2Of promoter,within
R14023 T20464 T20462 arg1Of promoter,the
R14024 T20464 T20463 arg1Of promoter,IL-1RA
R14025 T20466 T20465 arg1Of RNA,PBMC
R14026 T20466 T20467 arg1Of RNA,was
R14027 T20466 T20468 arg2Of RNA,isolated
R14028 T20468 T20467 arg2Of isolated,was
R14029 T20468 T20469 arg1Of isolated,with
R14030 T20468 T20473 arg1Of isolated,(
R14031 T20468 T20478 arg1Of isolated,and
R14032 T20472 T20469 arg2Of kit,with
R14033 T20472 T20470 arg1Of kit,an
R14034 T20472 T20471 arg1Of kit,RNeasy
R14035 T20474 T20473 arg2Of Qiagen,(
R14036 T20474 T20475 arg1Of Qiagen,","
R14037 T20476 T20475 arg2Of Germany,","
R14038 T20477 T20473 arg3Of ),(
R14039 T20478 T20511 arg1Of and,(
R14040 T20478 T20514 arg1Of and,(
R14041 T20478 T20555 arg1Of and,following
R14042 T20480 T20479 arg1Of RNA,messenger
R14043 T20480 T20481 arg1Of RNA,was
R14044 T20480 T20482 arg2Of RNA,transcribed
R14045 T20480 T20495 arg2Of RNA,analysed
R14046 T20482 T20483 arg1Of transcribed,into
R14047 T20482 T20494 arg1Of transcribed,and
R14048 T20484 T20483 arg2Of cDNA,into
R14049 T20484 T20485 arg1Of cDNA,with
R14050 T20489 T20487 arg1Of Strand,Ready
R14051 T20489 T20488 arg1Of Strand,First
R14052 T20490 T20485 arg2Of kit,with
R14053 T20490 T20486 arg1Of kit,Reactin
R14054 T20490 T20489 arg1Of kit,Strand
R14055 T20490 T20491 arg1Of kit,(
R14056 T20492 T20491 arg2Of Biomol,(
R14057 T20493 T20491 arg3Of ),(
R14058 T20494 T20478 arg2Of and,and
R14059 T20494 T20481 arg2Of and,was
R14060 T20495 T20494 arg2Of analysed,and
R14061 T20495 T20496 arg1Of analysed,for
R14062 T20497 T20498 arg1Of IL-1RA,and
R14063 T20499 T20498 arg2Of GAPDH,and
R14064 T20500 T20496 arg2Of transcripts,for
R14065 T20500 T20497 arg1Of transcripts,IL-1RA
R14066 T20500 T20499 arg1Of transcripts,GAPDH
R14067 T20502 T20495 arg1Of PCR,analysed
R14068 T20502 T20501 arg2Of PCR,by
R14069 T20502 T20503 arg1Of PCR,with
R14070 T20510 T20503 arg2Of mastermix,with
R14071 T20510 T20504 arg1Of mastermix,a
R14072 T20510 T20505 arg1Of mastermix,HotStart
R14073 T20510 T20506 arg1Of mastermix,""""
R14074 T20510 T20507 arg1Of mastermix,sweet
R14075 T20510 T20508 arg1Of mastermix,""""
R14076 T20510 T20509 arg1Of mastermix,PCR
R14077 T20512 T20511 arg2Of Biomol,(
R14078 T20513 T20511 arg3Of ),(
R14079 T20515 T20516 arg1Of 95°C,","
R14080 T20516 T20519 arg1Of ",",","
R14081 T20518 T20516 arg2Of sec,","
R14082 T20518 T20517 arg1Of sec,30
R14083 T20519 T20521 arg1Of ",",","
R14084 T20520 T20519 arg2Of 55°C,","
R14085 T20521 T20524 arg1Of ",",","
R14086 T20523 T20521 arg2Of sec,","
R14087 T20523 T20522 arg1Of sec,30
R14088 T20524 T20526 arg1Of ",",","
R14089 T20525 T20524 arg2Of 72°C,","
R14090 T20526 T20529 arg1Of ",",","
R14091 T20528 T20526 arg2Of sec,","
R14092 T20528 T20527 arg1Of sec,30
R14093 T20529 T20539 arg1Of ",",","
R14094 T20531 T20529 arg2Of cycles,","
R14095 T20531 T20530 arg1Of cycles,25
R14096 T20531 T20532 arg1Of cycles,for
R14097 T20533 T20534 arg1Of IL-1RA,and
R14098 T20534 T20532 arg2Of and,for
R14099 T20534 T20536 arg1Of and,for
R14100 T20535 T20534 arg2Of 94°C,and
R14101 T20538 T20536 arg2Of sec,for
R14102 T20538 T20537 arg1Of sec,30
R14103 T20539 T20549 arg1Of ",",","
R14104 T20540 T20539 arg2Of 50°C,","
R14105 T20540 T20541 arg1Of 50°C,for
R14106 T20543 T20544 arg1Of sec,and
R14107 T20544 T20541 arg2Of and,for
R14108 T20544 T20542 arg1Of and,30
R14109 T20544 T20546 arg1Of and,for
R14110 T20545 T20544 arg2Of 72°C,and
R14111 T20548 T20546 arg2Of sec,for
R14112 T20548 T20547 arg1Of sec,45
R14113 T20549 T20514 arg2Of ",",(
R14114 T20551 T20549 arg2Of cycles,","
R14115 T20551 T20550 arg1Of cycles,25
R14116 T20551 T20552 arg1Of cycles,for
R14117 T20553 T20552 arg2Of GAPDH,for
R14118 T20554 T20514 arg3Of ),(
R14119 T20558 T20555 arg2Of incubation,following
R14120 T20558 T20556 arg1Of incubation,18
R14121 T20558 T20557 arg1Of incubation,h
R14122 T20558 T20559 arg1Of incubation,with
R14123 T20560 T20559 arg2Of GP,with
R14124 T20562 T20561 arg1Of protein,IL-1RA
R14125 T20562 T20563 arg1Of protein,was
R14126 T20562 T20564 arg2Of protein,measured
R14127 T20564 T20563 arg2Of measured,was
R14128 T20564 T20565 arg1Of measured,in
R14129 T20564 T20570 arg1Of measured,after
R14130 T20567 T20565 arg2Of supernatant,in
R14131 T20567 T20566 arg1Of supernatant,the
R14132 T20567 T20568 arg1Of supernatant,by
R14133 T20569 T20568 arg2Of ELISA,by
R14134 T20571 T20572 arg1Of 24,h
R14135 T20573 T20570 arg2Of incubation,after
R14136 T20573 T20571 arg1Of incubation,24
R14137 T20573 T20574 arg1Of incubation,with
R14138 T20575 T20574 arg2Of GP,with
R14430 T21016 T21015 arg1Of analysis,Statistical
R14431 T21019 T21017 arg1Of test,The
R14432 T21019 T21018 arg1Of test,Kolmogorow-Smirnov
R14433 T21019 T21020 arg1Of test,was
R14434 T21019 T21021 arg2Of test,used
R14435 T21021 T21020 arg2Of used,was
R14436 T21023 T21021 arg3Of evaluate,used
R14437 T21023 T21022 arg1Of evaluate,to
R14438 T21023 T21024 arg1Of evaluate,","
R14439 T21027 T21026 arg1Of amounts,cytokine
R14440 T21027 T21028 arg1Of amounts,and
R14441 T21028 T21031 arg1Of and,to
R14442 T21028 T21034 arg1Of and,were
R14443 T21028 T21036 arg2Of and,distributed
R14444 T21030 T21028 arg2Of activities,and
R14445 T21030 T21029 arg1Of activities,binding
R14446 T21033 T21031 arg2Of factors,to
R14447 T21033 T21032 arg1Of factors,transcription
R14448 T21036 T21023 arg2Of distributed,evaluate
R14449 T21036 T21025 arg1Of distributed,whether
R14450 T21036 T21034 arg2Of distributed,were
R14451 T21036 T21035 arg1Of distributed,normally
R14452 T21038 T21037 arg1Of coefficients,Correlation
R14453 T21038 T21039 arg1Of coefficients,and
R14454 T21039 T21042 arg1Of and,were
R14455 T21039 T21043 arg2Of and,analyzed
R14456 T21041 T21039 arg2Of significances,and
R14457 T21041 T21040 arg1Of significances,corresponding
R14458 T21043 T21042 arg2Of analyzed,were
R14459 T21047 T21045 arg1Of test,the
R14460 T21047 T21046 arg1Of test,Pearson
R14461 T21047 T21048 arg1Of test,(
R14462 T21047 T21052 arg1Of test,or
R14463 T21050 T21048 arg2Of distribution,(
R14464 T21050 T21049 arg1Of distribution,normal
R14465 T21051 T21048 arg3Of ),(
R14466 T21052 T21043 arg1Of or,analyzed
R14467 T21052 T21044 arg2Of or,by
R14468 T21055 T21052 arg2Of test,or
R14469 T21055 T21053 arg1Of test,the
R14470 T21055 T21054 arg1Of test,Spearman
R14471 T21055 T21056 arg1Of test,(
R14472 T21058 T21056 arg2Of distribution,(
R14473 T21058 T21057 arg1Of distribution,non-normal
R14474 T21059 T21056 arg3Of ),(
R14475 T21061 T21060 arg1Of compare,To
R14476 T21061 T21064 arg1Of compare,to
R14477 T21063 T21061 arg2Of data,compare
R14478 T21063 T21062 arg1Of data,experimental
R14479 T21067 T21064 arg2Of value,to
R14480 T21067 T21065 arg1Of value,a
R14481 T21067 T21066 arg1Of value,theoretical
R14482 T21067 T21068 arg1Of value,(
R14483 T21069 T21068 arg2Of for,(
R14484 T21071 T21070 arg1Of GP,example
R14485 T21071 T21072 arg1Of GP,+
R14486 T21073 T21069 arg2Of TSST-1,for
R14487 T21073 T21071 arg1Of TSST-1,GP
R14488 T21073 T21074 arg1Of TSST-1,vs
R14489 T21076 T21074 arg2Of calc.,vs
R14490 T21076 T21075 arg1Of calc.,GP/TSST-1
R14491 T21077 T21068 arg3Of ),(
R14492 T21078 T21061 arg1Of we,compare
R14493 T21078 T21079 arg1Of we,calculated
R14494 T21078 T21087 arg1Of we,added
R14495 T21079 T21086 arg1Of calculated,and
R14496 T21081 T21079 arg2Of sum,calculated
R14497 T21081 T21080 arg1Of sum,the
R14498 T21081 T21082 arg1Of sum,of
R14499 T21085 T21082 arg2Of effects,of
R14500 T21085 T21083 arg1Of effects,the
R14501 T21085 T21084 arg1Of effects,individual
R14502 T21086 T21060 modOf and,To
R14503 T21087 T21086 arg2Of added,and
R14504 T21087 T21090 arg1Of added,into
R14505 T21089 T21087 arg2Of values,added
R14506 T21089 T21088 arg1Of values,these
R14507 T21092 T21091 arg1Of 1B,Fig.
R14508 T21092 T21093 arg1Of 1B,","
R14509 T21093 T21095 arg1Of ",",","
R14510 T21094 T21093 arg2Of 3,","
R14511 T21095 T21097 arg1Of ",",","
R14512 T21096 T21095 arg2Of 4,","
R14513 T21097 T21100 arg1Of ",",and
R14514 T21098 T21097 arg2Of 5,","
R14515 T21100 T21090 arg2Of and,into
R14516 T21100 T21099 arg1Of and,","
R14517 T21101 T21100 arg2Of 6,and
R14518 T21102 T21103 arg1Of Significances,of
R14519 T21102 T21134 arg1Of Significances,were
R14520 T21102 T21135 arg2Of Significances,analysed
R14521 T21104 T21103 arg2Of differences,of
R14522 T21104 T21105 arg1Of differences,between
R14523 T21104 T21118 arg1Of differences,between
R14524 T21104 T21124 arg1Of differences,(
R14525 T21105 T21117 arg1Of between,as
R14526 T21107 T21105 arg2Of data,between
R14527 T21107 T21106 arg1Of data,experimental
R14528 T21107 T21108 arg1Of data,(
R14529 T21109 T21108 arg2Of for,(
R14530 T21111 T21109 arg2Of GP,for
R14531 T21111 T21110 arg1Of GP,example
R14532 T21111 T21112 arg1Of GP,vs
R14533 T21113 T21112 arg2Of LPS,vs
R14534 T21114 T21108 arg3Of ),(
R14535 T21117 T21115 arg1Of as,as
R14536 T21117 T21116 arg1Of as,well
R14537 T21118 T21117 arg2Of between,as
R14538 T21120 T21119 arg1Of data,experimental
R14539 T21120 T21121 arg1Of data,and
R14540 T21121 T21118 arg2Of and,between
R14541 T21123 T21121 arg2Of values,and
R14542 T21123 T21122 arg1Of values,theoretical
R14543 T21125 T21124 arg2Of for,(
R14544 T21127 T21126 arg1Of GP,example
R14545 T21127 T21128 arg1Of GP,+
R14546 T21129 T21125 arg2Of TSST-1,for
R14547 T21129 T21127 arg1Of TSST-1,GP
R14548 T21129 T21130 arg1Of TSST-1,vs
R14549 T21132 T21130 arg2Of calc.,vs
R14550 T21132 T21131 arg1Of calc.,GP/TSST-1
R14551 T21133 T21124 arg3Of ),(
R14552 T21135 T21134 arg2Of analysed,were
R14553 T21135 T21136 modOf analysed,using
R14554 T21135 T21154 arg1Of analysed,","
R14555 T21135 T21155 arg1Of analysed,(
R14556 T21138 T21137 arg1Of Student,the
R14557 T21138 T21139 arg2Of Student,'s
R14558 T21140 T21139 arg1Of t-test,'s
R14559 T21140 T21141 arg1Of t-test,(
R14560 T21140 T21145 arg1Of t-test,or
R14561 T21143 T21141 arg2Of distribution,(
R14562 T21143 T21142 arg1Of distribution,normal
R14563 T21144 T21141 arg3Of ),(
R14564 T21145 T21136 arg2Of or,using
R14565 T21148 T21147 arg1Of Signed-Rank,Wilcoxon
R14566 T21149 T21145 arg2Of test,or
R14567 T21149 T21146 arg1Of test,the
R14568 T21149 T21148 arg1Of test,Signed-Rank
R14569 T21149 T21150 arg1Of test,(
R14570 T21152 T21150 arg2Of distribution,(
R14571 T21152 T21151 arg1Of distribution,non-normal
R14572 T21153 T21150 arg3Of ),(
R14573 T21156 T21157 arg1Of SPSS,for
R14574 T21156 T21159 arg1Of SPSS,;
R14575 T21158 T21157 arg2Of Windows,for
R14576 T21159 T21155 arg2Of ;,(
R14577 T21162 T21159 arg2Of Software,;
R14578 T21162 T21160 arg1Of Software,SPSS
R14579 T21162 T21161 arg1Of Software,Science
R14580 T21162 T21163 arg1Of Software,","
R14581 T21164 T21163 arg2Of Erkrath,","
R14582 T21164 T21165 arg1Of Erkrath,","
R14583 T21166 T21165 arg2Of Germany,","
R14584 T21167 T21155 arg3Of ),(
R14768 T21597 T21595 arg1Of GP,A
R14769 T21597 T21596 arg1Of GP,","
R14770 T21597 T21598 arg1Of GP,led
R14771 T21598 T21599 arg1Of led,to
R14772 T21601 T21599 arg2Of binding,to
R14773 T21601 T21600 arg1Of binding,DNA
R14774 T21601 T21602 arg1Of binding,of
R14775 T21603 T21604 arg1Of NFAT,","
R14776 T21604 T21606 arg1Of ",",and
R14777 T21605 T21604 arg2Of NFκB,","
R14778 T21606 T21602 arg2Of and,of
R14779 T21607 T21606 arg2Of NFIL-6,and
R14780 T21609 T21608 arg1Of PBMC,Human
R14781 T21609 T21610 arg1Of PBMC,were
R14782 T21609 T21611 arg2Of PBMC,incubated
R14783 T21611 T21610 arg2Of incubated,were
R14784 T21611 T21612 arg1Of incubated,with
R14785 T21611 T21615 arg1Of incubated,or
R14786 T21614 T21612 arg2Of control,with
R14787 T21614 T21613 arg1Of control,medium
R14788 T21616 T21617 arg1Of GP,(
R14789 T21616 T21623 arg1Of GP,for
R14790 T21616 T21630 arg1Of GP,were
R14791 T21616 T21631 arg2Of GP,incubated
R14792 T21618 T21619 arg1Of 1,and
R14793 T21620 T21619 arg2Of 100,and
R14794 T21621 T21617 arg2Of μg,(
R14795 T21621 T21618 arg1Of μg,1
R14796 T21621 T21620 arg1Of μg,100
R14797 T21622 T21617 arg3Of ),(
R14798 T21625 T21623 arg2Of h,for
R14799 T21625 T21624 arg1Of h,1
R14800 T21625 T21626 arg1Of h,at
R14801 T21628 T21627 arg1Of Nuclear,37°C.
R14802 T21629 T21626 arg2Of extracts,at
R14803 T21629 T21628 arg1Of extracts,Nuclear
R14804 T21631 T21615 arg2Of incubated,or
R14805 T21631 T21630 arg2Of incubated,were
R14806 T21631 T21632 arg1Of incubated,with
R14807 T21635 T21636 arg1Of NFAT,","
R14808 T21636 T21638 arg1Of ",",","
R14809 T21637 T21636 arg2Of NFκB,","
R14810 T21638 T21640 arg1Of ",",or
R14811 T21639 T21638 arg2Of NFIL-6,","
R14812 T21641 T21640 arg2Of NFκB-IL-8,or
R14813 T21643 T21632 arg2Of probe,with
R14814 T21643 T21633 arg1Of probe,a
R14815 T21643 T21634 arg1Of probe,32P-labeled
R14816 T21643 T21635 arg1Of probe,NFAT
R14817 T21643 T21637 arg1Of probe,NFκB
R14818 T21643 T21639 arg1Of probe,NFIL-6
R14819 T21643 T21641 arg1Of probe,NFκB-IL-8
R14820 T21643 T21642 arg1Of probe,oligonucleotide
R14821 T21643 T21644 arg1Of probe,corresponding
R14822 T21644 T21645 arg1Of corresponding,to
R14823 T21647 T21648 arg1Of IFNγ,","
R14824 T21648 T21650 arg1Of ",",","
R14825 T21649 T21648 arg2Of TNFα,","
R14826 T21650 T21652 arg1Of ",",and
R14827 T21651 T21650 arg2Of IL-6,","
R14828 T21653 T21652 arg2Of IL-8,and
R14829 T21655 T21645 arg2Of promoters,to
R14830 T21655 T21646 arg1Of promoters,the
R14831 T21655 T21647 arg1Of promoters,IFNγ
R14832 T21655 T21649 arg1Of promoters,TNFα
R14833 T21655 T21651 arg1Of promoters,IL-6
R14834 T21655 T21653 arg1Of promoters,IL-8
R14835 T21655 T21654 arg1Of promoters,gene
R14836 T21655 T21656 arg1Of promoters,(
R14837 T21658 T21656 arg2Of 1,(
R14838 T21658 T21657 arg1Of 1,Table
R14839 T21659 T21656 arg3Of ),(
R14840 T21660 T21661 arg1Of Arrows,with
R14841 T21660 T21665 arg1Of Arrows,indicate
R14842 T21664 T21661 arg2Of head,with
R14843 T21664 T21662 arg1Of head,the
R14844 T21664 T21663 arg1Of head,black
R14845 T21665 T21678 arg1Of indicate,compared
R14846 T21667 T21665 arg2Of location,indicate
R14847 T21667 T21666 arg1Of location,migrational
R14848 T21667 T21668 arg1Of location,of
R14849 T21670 T21671 arg1Of NFAT-DNA,","
R14850 T21671 T21673 arg1Of ",",","
R14851 T21672 T21671 arg2Of NFκB-DNA,","
R14852 T21673 T21675 arg1Of ",",or
R14853 T21674 T21673 arg2Of NFIL-6-DNA,","
R14854 T21676 T21675 arg2Of NFκB-IL-8-DNA,or
R14855 T21677 T21668 arg2Of complex,of
R14856 T21677 T21669 arg1Of complex,the
R14857 T21677 T21670 arg1Of complex,NFAT-DNA
R14858 T21677 T21672 arg1Of complex,NFκB-DNA
R14859 T21677 T21674 arg1Of complex,NFIL-6-DNA
R14860 T21677 T21676 arg1Of complex,NFκB-IL-8-DNA
R14861 T21679 T21678 arg2Of to,compared
R14862 T21681 T21679 arg2Of probe,to
R14863 T21681 T21680 arg1Of probe,free
R14864 T21681 T21682 arg1Of probe,(
R14865 T21684 T21682 arg2Of shift,(
R14866 T21684 T21683 arg1Of shift,no
R14867 T21685 T21682 arg3Of ),(
R14868 T21686 T21687 arg1Of Arrow,with
R14869 T21686 T21691 arg1Of Arrow,indicates
R14870 T21690 T21687 arg2Of head,with
R14871 T21690 T21688 arg1Of head,the
R14872 T21690 T21689 arg1Of head,open
R14873 T21691 T21698 arg1Of indicates,","
R14874 T21691 T21699 arg1Of indicates,respectively
R14875 T21693 T21691 arg2Of supershift,indicates
R14876 T21693 T21692 arg1Of supershift,a
R14877 T21693 T21694 arg1Of supershift,of
R14878 T21695 T21696 arg1Of NFκB-IL-8-DNA-anti-p65,and
R14879 T21696 T21694 arg2Of and,of
R14880 T21697 T21696 arg2Of -p50,and
R14881 T21701 T21700 arg1Of autoradiogram,An
R14882 T21701 T21702 arg1Of autoradiogram,from
R14883 T21701 T21706 arg1Of autoradiogram,is
R14884 T21701 T21707 arg2Of autoradiogram,shown
R14885 T21705 T21702 arg2Of experiment,from
R14886 T21705 T21703 arg1Of experiment,a
R14887 T21705 T21704 arg1Of experiment,representative
R14888 T21707 T21706 arg2Of shown,is
R14889 T21707 T21708 arg1Of shown,(
R14890 T21709 T21708 arg2Of n,(
R14891 T21709 T21710 arg1Of n,=
R14892 T21709 T21711 arg1Of n,7
R14893 T21712 T21708 arg3Of ),(
R14894 T21713 T21715 arg1Of B,Decreased
R14895 T21715 T21714 arg1Of Decreased,","
R14896 T21717 T21715 arg2Of binding,Decreased
R14897 T21717 T21716 arg1Of binding,DNA
R14898 T21717 T21718 arg1Of binding,of
R14899 T21717 T21720 arg1Of binding,following
R14900 T21717 T21724 arg1Of binding,","
R14901 T21717 T21725 arg1Of binding,compared
R14902 T21719 T21718 arg2Of NFκB,of
R14903 T21723 T21720 arg2Of TSST-1,following
R14904 T21723 T21721 arg1Of TSST-1,GP
R14905 T21723 T21722 arg1Of TSST-1,+
R14906 T21726 T21725 arg2Of to,compared
R14907 T21727 T21728 arg1Of TSST-1,","
R14908 T21728 T21731 arg1Of ",",or
R14909 T21729 T21728 arg2Of GP,","
R14910 T21731 T21726 arg2Of or,to
R14911 T21731 T21730 arg1Of or,","
R14912 T21732 T21731 arg2Of TSST-1/GP,or
R14913 T21734 T21733 arg1Of PBMC,Human
R14914 T21734 T21735 arg1Of PBMC,were
R14915 T21734 T21736 arg2Of PBMC,incubated
R14916 T21734 T21751 arg1Of PBMC,GP
R14917 T21736 T21735 arg2Of incubated,were
R14918 T21736 T21737 arg1Of incubated,with
R14919 T21736 T21751 modOf incubated,GP
R14920 T21739 T21738 arg1Of control,medium
R14921 T21739 T21740 arg1Of control,","
R14922 T21740 T21742 arg1Of ",",","
R14923 T21741 T21740 arg2Of LPS,","
R14924 T21742 T21744 arg1Of ",",","
R14925 T21743 T21742 arg2Of TSST-1,","
R14926 T21744 T21737 arg2Of ",",with
R14927 T21745 T21744 arg2Of GP,","
R14928 T21745 T21746 arg1Of GP,(
R14929 T21748 T21746 arg2Of μg,(
R14930 T21748 T21747 arg1Of μg,100
R14931 T21749 T21746 arg3Of ),(
R14932 T21751 T21750 arg1Of GP,","
R14933 T21753 T21754 arg1Of TSST-1,and
R14934 T21754 T21758 arg1Of and,for
R14935 T21754 T21769 arg1Of and,is
R14936 T21754 T21770 arg2Of and,shown
R14937 T21757 T21754 arg2Of LPS,and
R14938 T21757 T21755 arg1Of LPS,GP
R14939 T21757 T21756 arg1Of LPS,+
R14940 T21760 T21758 arg2Of h,for
R14941 T21760 T21759 arg1Of h,1
R14942 T21760 T21761 arg1Of h,at
R14943 T21763 T21762 arg1Of An,37°C.
R14944 T21764 T21761 arg2Of autoradiogram,at
R14945 T21764 T21763 arg1Of autoradiogram,An
R14946 T21764 T21765 arg1Of autoradiogram,from
R14947 T21768 T21765 arg2Of experiment,from
R14948 T21768 T21766 arg1Of experiment,a
R14949 T21768 T21767 arg1Of experiment,representative
R14950 T21770 T21751 arg2Of shown,GP
R14951 T21770 T21752 arg1Of shown,+
R14952 T21770 T21769 arg2Of shown,is
R14953 T21772 T21771 arg1Of representation,Schematic
R14954 T21772 T21773 arg1Of representation,of
R14955 T21772 T21777 arg1Of representation,following
R14956 T21772 T21794 arg1Of representation,as
R14957 T21776 T21773 arg2Of activity,of
R14958 T21776 T21774 arg1Of activity,NFκB-DNA
R14959 T21776 T21775 arg1Of activity,binding
R14960 T21778 T21779 arg1Of GP,(
R14961 T21778 T21785 arg1Of GP,or
R14962 T21780 T21781 arg1Of 1,and
R14963 T21782 T21781 arg2Of 100,and
R14964 T21783 T21779 arg2Of μg,(
R14965 T21783 T21780 arg1Of μg,1
R14966 T21783 T21782 arg1Of μg,100
R14967 T21784 T21779 arg3Of ),(
R14968 T21785 T21777 arg2Of or,following
R14969 T21787 T21785 arg2Of treatment,or
R14970 T21787 T21786 arg1Of treatment,TSST-1
R14971 T21787 T21788 arg1Of treatment,(
R14972 T21790 T21788 arg2Of ng,(
R14973 T21790 T21789 arg1Of ng,250
R14974 T21791 T21788 arg3Of ),(
R14975 T21794 T21792 arg1Of as,as
R14976 T21794 T21793 arg1Of as,well
R14977 T21794 T21800 arg1Of as,and
R14978 T21796 T21794 arg2Of administration,as
R14979 T21796 T21795 arg1Of administration,simultaneous
R14980 T21796 T21797 arg1Of administration,of
R14981 T21799 T21797 arg2Of compounds,of
R14982 T21799 T21798 arg1Of compounds,both
R14983 T21803 T21800 arg2Of value,and
R14984 T21803 T21801 arg1Of value,the
R14985 T21803 T21802 arg1Of value,theoretical
R14986 T21803 T21804 arg1Of value,(
R14987 T21806 T21804 arg2Of calc.,(
R14988 T21806 T21805 arg1Of calc.,GP/TSST-1
R14989 T21807 T21804 arg3Of ),(
R14990 T21810 T21808 arg1Of levels,Medium
R14991 T21810 T21809 arg1Of levels,control
R14992 T21810 T21811 arg1Of levels,were
R14993 T21810 T21812 arg2Of levels,set
R14994 T21812 T21811 arg2Of set,were
R14995 T21813 T21812 arg3Of equal,set
R14996 T21813 T21826 modOf equal,are
R14997 T21815 T21814 arg1Of 1±,to
R14998 T21815 T21826 arg1Of 1±,are
R14999 T21815 T21827 arg2Of 1±,shown
R15000 T21816 T21817 arg1Of SEM,and
R15001 T21817 T21815 arg2Of and,1±
R15002 T21817 T21819 arg1Of and,(
R15003 T21818 T21817 arg2Of significances,and
R15004 T21822 T21819 arg2Of p,(
R15005 T21822 T21820 arg1Of p,*
R15006 T21822 T21821 arg1Of p,=
R15007 T21822 T21823 arg1Of p,<
R15008 T21822 T21824 arg1Of p,0.05
R15009 T21825 T21819 arg3Of ),(
R15010 T21827 T21826 arg2Of shown,are
R15011 T21827 T21828 arg1Of shown,with
R15012 T21829 T21828 arg2Of respect,with
R15013 T21829 T21830 arg1Of respect,to
R15014 T21832 T21830 arg2Of control,to
R15015 T21832 T21831 arg1Of control,medium
R15016 T21832 T21833 arg1Of control,(
R15017 T21834 T21833 arg2Of n,(
R15018 T21834 T21835 arg1Of n,=
R15019 T21834 T21836 arg1Of n,4
R15020 T21837 T21833 arg3Of ),(
R15340 T22471 T22470 arg1Of p65/p50,NFκB
R15341 T22471 T22472 arg1Of p65/p50,and
R15342 T22472 T22474 arg1Of and,were
R15343 T22472 T22475 arg2Of and,involved
R15344 T22473 T22472 arg2Of NFATc2/c1,and
R15345 T22475 T22474 arg2Of involved,were
R15346 T22475 T22476 arg1Of involved,in
R15347 T22479 T22476 arg2Of binding,in
R15348 T22479 T22477 arg1Of binding,GP-induced
R15349 T22479 T22478 arg1Of binding,DNA
R15350 T22481 T22480 arg2Of order,In
R15351 T22483 T22480 arg3Of determine,In
R15352 T22483 T22482 arg1Of determine,to
R15353 T22488 T22485 arg1Of proteins,the
R15354 T22488 T22486 arg1Of proteins,DNA
R15355 T22488 T22487 arg1Of proteins,binding
R15356 T22488 T22489 arg2Of proteins,activated
R15357 T22488 T22492 arg1Of proteins,were
R15358 T22488 T22493 arg2Of proteins,related
R15359 T22491 T22489 arg1Of GP,activated
R15360 T22491 T22490 arg2Of GP,by
R15361 T22493 T22483 arg2Of related,determine
R15362 T22493 T22484 arg1Of related,whether
R15363 T22493 T22492 arg2Of related,were
R15364 T22493 T22494 arg1Of related,to
R15365 T22495 T22496 arg1Of NFκB,and
R15366 T22496 T22494 arg2Of and,to
R15367 T22497 T22496 arg2Of NFAT,and
R15368 T22502 T22501 arg2Of dot,(
R15369 T22503 T22501 arg3Of ),(
R15370 T22504 T22483 arg1Of blot,determine
R15371 T22504 T22499 arg1Of blot,an
R15372 T22504 T22500 arg1Of blot,immuno
R15373 T22504 T22501 arg1Of blot,(
R15374 T22504 T22505 arg1Of blot,was
R15375 T22504 T22506 arg2Of blot,performed
R15376 T22506 T22480 arg1Of performed,In
R15377 T22506 T22498 arg1Of performed,","
R15378 T22506 T22505 arg2Of performed,was
R15379 T22512 T22507 arg1Of staining,A
R15380 T22512 T22508 arg1Of staining,representative
R15381 T22512 T22509 arg1Of staining,dot
R15382 T22512 T22510 arg1Of staining,blot
R15383 T22512 T22511 arg1Of staining,showing
R15384 T22512 T22513 arg1Of staining,of
R15385 T22512 T22573 arg1Of staining,is
R15386 T22512 T22574 arg2Of staining,shown
R15387 T22514 T22515 arg1Of negative,and
R15388 T22516 T22515 arg2Of positive,and
R15389 T22517 T22514 arg1Of controls,negative
R15390 T22517 T22516 arg1Of controls,positive
R15391 T22517 T22518 arg1Of controls,(
R15392 T22517 T22544 arg1Of controls,in
R15393 T22517 T22548 arg1Of controls,and
R15394 T22522 T22518 arg2Of p52,(
R15395 T22522 T22519 arg1Of p52,recombinant
R15396 T22522 T22520 arg1Of p52,proteins
R15397 T22522 T22521 arg1Of p52,NFκB
R15398 T22522 T22523 arg1Of p52,","
R15399 T22522 T22525 arg1Of p52,;
R15400 T22524 T22523 arg2Of c-rel,","
R15401 T22527 T22525 arg2Of extracts,;
R15402 T22527 T22526 arg1Of extracts,nuclear
R15403 T22527 T22528 arg1Of extracts,of
R15404 T22527 T22532 arg1Of extracts,positive
R15405 T22527 T22541 arg1Of extracts,","
R15406 T22531 T22528 arg2Of cells,of
R15407 T22531 T22529 arg1Of cells,PMA-treated
R15408 T22531 T22530 arg1Of cells,Jurkat
R15409 T22532 T22533 arg1Of positive,for
R15410 T22532 T22539 arg1Of positive,for
R15411 T22533 T22538 arg1Of for,and
R15412 T22535 T22534 arg1Of p50,NFκB
R15413 T22535 T22536 arg1Of p50,","
R15414 T22536 T22533 arg2Of ",",for
R15415 T22537 T22536 arg2Of p65,","
R15416 T22539 T22538 arg2Of for,and
R15417 T22540 T22539 arg2Of NFATc1,for
R15418 T22542 T22541 arg2Of c2,","
R15419 T22543 T22518 arg3Of ),(
R15420 T22547 T22544 arg2Of panel,in
R15421 T22547 T22545 arg1Of panel,the
R15422 T22547 T22546 arg1Of panel,upper
R15423 T22548 T22513 arg2Of and,of
R15424 T22549 T22548 arg2Of staining,and
R15425 T22549 T22550 arg1Of staining,of
R15426 T22552 T22550 arg2Of extracts,of
R15427 T22552 T22551 arg1Of extracts,nuclear
R15428 T22552 T22553 arg1Of extracts,of
R15429 T22552 T22556 arg1Of extracts,(
R15430 T22552 T22569 arg1Of extracts,in
R15431 T22555 T22553 arg2Of PBMC,of
R15432 T22555 T22554 arg1Of PBMC,GP-treated
R15433 T22557 T22556 arg2Of positive,(
R15434 T22557 T22558 arg1Of positive,for
R15435 T22560 T22559 arg1Of p65,NFκB
R15436 T22560 T22561 arg1Of p65,","
R15437 T22561 T22558 arg2Of ",",for
R15438 T22561 T22566 arg1Of ",",","
R15439 T22562 T22563 arg1Of p50,and
R15440 T22564 T22563 arg2Of NFAT,and
R15441 T22565 T22561 arg2Of c2,","
R15442 T22565 T22562 arg1Of c2,p50
R15443 T22565 T22564 arg1Of c2,NFAT
R15444 T22567 T22566 arg2Of c1,","
R15445 T22568 T22556 arg3Of ),(
R15446 T22572 T22569 arg2Of panel,in
R15447 T22572 T22570 arg1Of panel,the
R15448 T22572 T22571 arg1Of panel,lower
R15449 T22574 T22573 arg2Of shown,is
R15450 T22574 T22575 arg1Of shown,(
R15451 T22576 T22575 arg2Of n,(
R15452 T22576 T22577 arg1Of n,=
R15453 T22576 T22578 arg1Of n,3
R15454 T22579 T22575 arg3Of ),(
R15658 T23080 T23078 arg1Of IL-1β,A
R15659 T23080 T23079 arg1Of IL-1β,","
R15660 T23080 T23081 arg1Of IL-1β,was
R15661 T23080 T23082 arg2Of IL-1β,down-regulated
R15662 T23080 T23095 arg1Of IL-1β,compared
R15663 T23082 T23081 arg2Of down-regulated,was
R15664 T23082 T23083 arg1Of down-regulated,(
R15665 T23082 T23090 arg1Of down-regulated,following
R15666 T23082 T23094 arg1Of down-regulated,when
R15667 T23086 T23085 arg1Of –,h
R15668 T23088 T23083 arg2Of h,(
R15669 T23088 T23084 arg1Of h,12
R15670 T23088 T23086 arg1Of h,–
R15671 T23088 T23087 arg1Of h,24
R15672 T23089 T23083 arg3Of ),(
R15673 T23093 T23090 arg2Of TSST-1,following
R15674 T23093 T23091 arg1Of TSST-1,GP
R15675 T23093 T23092 arg1Of TSST-1,+
R15676 T23095 T23094 arg2Of compared,when
R15677 T23095 T23096 arg1Of compared,to
R15678 T23097 T23096 arg2Of TSST-1,to
R15679 T23099 T23098 arg1Of course,Time
R15680 T23099 T23100 arg1Of course,(
R15681 T23099 T23104 arg1Of course,of
R15682 T23102 T23100 arg2Of h,(
R15683 T23102 T23101 arg1Of h,48
R15684 T23103 T23100 arg3Of ),(
R15685 T23106 T23104 arg2Of production,of
R15686 T23106 T23105 arg1Of production,IL-1β
R15687 T23106 T23107 arg1Of production,(
R15688 T23106 T23110 arg1Of production,by
R15689 T23106 T23113 arg2Of production,incubated
R15690 T23108 T23107 arg2Of pg/ml,(
R15691 T23109 T23107 arg3Of ),(
R15692 T23112 T23110 arg2Of PBMC,by
R15693 T23112 T23111 arg1Of PBMC,human
R15694 T23113 T23114 arg1Of incubated,with
R15695 T23116 T23115 arg1Of control,medium
R15696 T23116 T23117 arg1Of control,","
R15697 T23117 T23121 arg1Of ",",","
R15698 T23120 T23117 arg2Of GP,","
R15699 T23120 T23118 arg1Of GP,100
R15700 T23120 T23119 arg1Of GP,μg
R15701 T23121 T23125 arg1Of ",",","
R15702 T23124 T23121 arg2Of TSST-1,","
R15703 T23124 T23122 arg1Of TSST-1,250
R15704 T23124 T23123 arg1Of TSST-1,ng
R15705 T23125 T23129 arg1Of ",",","
R15706 T23128 T23125 arg2Of TSST-1,","
R15707 T23128 T23126 arg1Of TSST-1,GP
R15708 T23128 T23127 arg1Of TSST-1,+
R15709 T23129 T23133 arg1Of ",",and
R15710 T23132 T23129 arg2Of LPS,","
R15711 T23132 T23130 arg1Of LPS,250
R15712 T23132 T23131 arg1Of LPS,ng
R15713 T23133 T23114 arg2Of and,with
R15714 T23136 T23133 arg2Of LPS,and
R15715 T23136 T23134 arg1Of LPS,GP
R15716 T23136 T23135 arg1Of LPS,+
R15717 T23139 T23138 arg1Of h,18
R15718 T23139 T23140 arg1Of h,and
R15719 T23140 T23137 arg2Of and,At
R15720 T23142 T23140 arg2Of h,and
R15721 T23142 T23141 arg1Of h,24
R15722 T23143 T23144 arg1Of there,was
R15723 T23143 T23156 arg1Of there,compared
R15724 T23144 T23137 arg1Of was,At
R15725 T23144 T23151 arg1Of was,following
R15726 T23144 T23155 arg1Of was,when
R15727 T23147 T23144 arg2Of reduction,was
R15728 T23147 T23145 arg1Of reduction,a
R15729 T23147 T23146 arg1Of reduction,marked
R15730 T23147 T23148 arg1Of reduction,in
R15731 T23150 T23148 arg2Of production,in
R15732 T23150 T23149 arg1Of production,IL-1β
R15733 T23154 T23151 arg2Of TSST-1,following
R15734 T23154 T23152 arg1Of TSST-1,GP
R15735 T23154 T23153 arg1Of TSST-1,+
R15736 T23156 T23155 arg2Of compared,when
R15737 T23156 T23157 arg1Of compared,to
R15738 T23158 T23157 arg2Of TSST-1,to
R15739 T23158 T23159 arg1Of TSST-1,(
R15740 T23162 T23159 arg2Of p,(
R15741 T23162 T23160 arg1Of p,*
R15742 T23162 T23161 arg1Of p,=
R15743 T23162 T23163 arg1Of p,<
R15744 T23162 T23164 arg1Of p,0.05
R15745 T23165 T23159 arg3Of ),(
R15746 T23166 T23167 arg1Of Graphs,depicting
R15747 T23166 T23177 arg1Of Graphs,are
R15748 T23166 T23179 arg2Of Graphs,shown
R15749 T23170 T23167 arg2Of values,depicting
R15750 T23170 T23168 arg1Of values,the
R15751 T23170 T23169 arg1Of values,theoretical
R15752 T23170 T23171 arg1Of values,for
R15753 T23173 T23172 arg1Of calc.,GP/LPS
R15754 T23173 T23174 arg1Of calc.,and
R15755 T23174 T23171 arg2Of and,for
R15756 T23176 T23174 arg2Of calc.,and
R15757 T23176 T23175 arg1Of calc.,GP/TSST-1
R15758 T23179 T23177 arg2Of shown,are
R15759 T23179 T23178 arg1Of shown,also
R15760 T23181 T23180 arg1Of levels,IL-1β
R15761 T23181 T23182 arg1Of levels,in
R15762 T23181 T23185 arg1Of levels,were
R15763 T23181 T23186 arg2Of levels,obtained
R15764 T23181 T23190 arg1Of levels,are
R15765 T23181 T23191 arg2Of levels,shown
R15766 T23184 T23182 arg2Of supernatnant,in
R15767 T23184 T23183 arg1Of supernatnant,the
R15768 T23186 T23185 arg2Of obtained,were
R15769 T23186 T23187 arg1Of obtained,by
R15770 T23186 T23189 arg1Of obtained,and
R15771 T23188 T23187 arg2Of Elisa,by
R15772 T23191 T23189 arg2Of shown,and
R15773 T23191 T23190 arg2Of shown,are
R15774 T23191 T23192 arg1Of shown,as
R15775 T23195 T23192 arg2Of SEM,as
R15776 T23195 T23193 arg1Of SEM,mean
R15777 T23195 T23194 arg1Of SEM,±
R15778 T23195 T23196 arg1Of SEM,(
R15779 T23197 T23196 arg2Of n,(
R15780 T23197 T23198 arg1Of n,=
R15781 T23197 T23199 arg1Of n,3
R15782 T23200 T23196 arg3Of ),(
R15783 T23201 T23202 arg1Of B,","
R15784 T23201 T23204 arg1Of B,was
R15785 T23201 T23205 arg2Of B,exaggerated
R15786 T23203 T23202 arg2Of IL-1RA,","
R15787 T23205 T23204 arg2Of exaggerated,was
R15788 T23205 T23206 arg1Of exaggerated,following
R15789 T23205 T23217 arg1Of exaggerated,when
R15790 T23209 T23206 arg2Of TSST-1,following
R15791 T23209 T23207 arg1Of TSST-1,GP
R15792 T23209 T23208 arg1Of TSST-1,+
R15793 T23209 T23210 arg1Of TSST-1,(
R15794 T23213 T23212 arg1Of –,h
R15795 T23215 T23210 arg2Of h,(
R15796 T23215 T23211 arg1Of h,12
R15797 T23215 T23213 arg1Of h,–
R15798 T23215 T23214 arg1Of h,48
R15799 T23216 T23210 arg3Of ),(
R15800 T23218 T23217 arg2Of compared,when
R15801 T23218 T23219 arg1Of compared,to
R15802 T23220 T23219 arg2Of TSST-1,to
R15803 T23222 T23221 arg1Of course,Time
R15804 T23222 T23223 arg1Of course,(
R15805 T23222 T23227 arg1Of course,of
R15806 T23225 T23223 arg2Of h,(
R15807 T23225 T23224 arg1Of h,48
R15808 T23226 T23223 arg3Of ),(
R15809 T23229 T23227 arg2Of production,of
R15810 T23229 T23228 arg1Of production,IL-1RA
R15811 T23229 T23230 arg1Of production,(
R15812 T23229 T23233 arg1Of production,by
R15813 T23229 T23236 arg2Of production,incubated
R15814 T23231 T23230 arg2Of pg/ml,(
R15815 T23232 T23230 arg3Of ),(
R15816 T23235 T23233 arg2Of PBMC,by
R15817 T23235 T23234 arg1Of PBMC,human
R15818 T23236 T23237 arg1Of incubated,with
R15819 T23239 T23238 arg1Of control,medium
R15820 T23239 T23240 arg1Of control,","
R15821 T23240 T23244 arg1Of ",",","
R15822 T23243 T23240 arg2Of GP,","
R15823 T23243 T23241 arg1Of GP,100
R15824 T23243 T23242 arg1Of GP,μg
R15825 T23244 T23248 arg1Of ",",","
R15826 T23247 T23244 arg2Of TSST-1,","
R15827 T23247 T23245 arg1Of TSST-1,250
R15828 T23247 T23246 arg1Of TSST-1,ng
R15829 T23248 T23252 arg1Of ",",","
R15830 T23251 T23248 arg2Of TSST-1,","
R15831 T23251 T23249 arg1Of TSST-1,GP
R15832 T23251 T23250 arg1Of TSST-1,+
R15833 T23252 T23256 arg1Of ",",and
R15834 T23255 T23252 arg2Of LPS,","
R15835 T23255 T23253 arg1Of LPS,250
R15836 T23255 T23254 arg1Of LPS,ng
R15837 T23256 T23237 arg2Of and,with
R15838 T23259 T23256 arg2Of LPS,and
R15839 T23259 T23257 arg1Of LPS,GP
R15840 T23259 T23258 arg1Of LPS,+
R15841 T23262 T23261 arg1Of h,18
R15842 T23262 T23263 arg1Of h,and
R15843 T23263 T23260 arg2Of and,Between
R15844 T23265 T23263 arg2Of h,and
R15845 T23265 T23264 arg1Of h,48
R15846 T23268 T23260 arg3Of treatment,Between
R15847 T23268 T23266 arg1Of treatment,a
R15848 T23268 T23267 arg1Of treatment,simultaneous
R15849 T23268 T23269 arg1Of treatment,of
R15850 T23268 T23271 arg1Of treatment,with
R15851 T23270 T23269 arg2Of PBMC,of
R15852 T23272 T23271 arg2Of GP,with
R15853 T23274 T23273 arg1Of TSST-1,+
R15854 T23274 T23275 arg1Of TSST-1,led
R15855 T23275 T23260 arg1Of led,Between
R15856 T23275 T23276 arg1Of led,to
R15857 T23275 T23286 arg1Of led,when
R15858 T23279 T23276 arg2Of effect,to
R15859 T23279 T23277 arg1Of effect,a
R15860 T23279 T23278 arg1Of effect,synergistic
R15861 T23279 T23280 arg1Of effect,","
R15862 T23285 T23280 arg2Of production,","
R15863 T23285 T23281 arg1Of production,i.e.
R15864 T23285 T23282 arg1Of production,a
R15865 T23285 T23283 arg1Of production,higher
R15866 T23285 T23284 arg1Of production,IL-1RA
R15867 T23287 T23286 arg2Of compared,when
R15868 T23287 T23288 arg1Of compared,to
R15869 T23290 T23288 arg2Of addition,to
R15870 T23290 T23289 arg1Of addition,an
R15871 T23290 T23291 arg1Of addition,of
R15872 T23290 T23295 arg1Of addition,for
R15873 T23294 T23291 arg2Of values,of
R15874 T23294 T23292 arg1Of values,the
R15875 T23294 T23293 arg1Of values,single
R15876 T23296 T23297 arg1Of TSST-1,and
R15877 T23297 T23295 arg2Of and,for
R15878 T23297 T23299 arg1Of and,(
R15879 T23298 T23297 arg2Of GP,and
R15880 T23302 T23299 arg2Of p,(
R15881 T23302 T23300 arg1Of p,*
R15882 T23302 T23301 arg1Of p,=
R15883 T23302 T23303 arg1Of p,<
R15884 T23302 T23304 arg1Of p,0.05
R15885 T23305 T23299 arg3Of ),(
R15886 T23306 T23307 arg1Of Graphs,depicting
R15887 T23306 T23317 arg1Of Graphs,are
R15888 T23306 T23318 arg2Of Graphs,included
R15889 T23310 T23307 arg2Of values,depicting
R15890 T23310 T23308 arg1Of values,the
R15891 T23310 T23309 arg1Of values,theoretical
R15892 T23310 T23311 arg1Of values,for
R15893 T23313 T23312 arg1Of calc.,GP/LPS
R15894 T23313 T23314 arg1Of calc.,and
R15895 T23314 T23311 arg2Of and,for
R15896 T23316 T23314 arg2Of calc.,and
R15897 T23316 T23315 arg1Of calc.,GP/TSST-1
R15898 T23318 T23317 arg2Of included,are
R15899 T23320 T23319 arg1Of levels,IL-1RA
R15900 T23320 T23321 arg1Of levels,in
R15901 T23320 T23324 arg1Of levels,were
R15902 T23320 T23325 arg2Of levels,obtained
R15903 T23320 T23329 arg1Of levels,are
R15904 T23320 T23330 arg2Of levels,shown
R15905 T23323 T23321 arg2Of supernatnant,in
R15906 T23323 T23322 arg1Of supernatnant,the
R15907 T23325 T23324 arg2Of obtained,were
R15908 T23325 T23326 arg1Of obtained,by
R15909 T23325 T23328 arg1Of obtained,and
R15910 T23327 T23326 arg2Of Elisa,by
R15911 T23330 T23328 arg2Of shown,and
R15912 T23330 T23329 arg2Of shown,are
R15913 T23330 T23331 arg1Of shown,as
R15914 T23334 T23331 arg2Of SEM,as
R15915 T23334 T23332 arg1Of SEM,mean
R15916 T23334 T23333 arg1Of SEM,±
R15917 T23334 T23335 arg1Of SEM,(
R15918 T23336 T23335 arg2Of n,(
R15919 T23336 T23337 arg1Of n,=
R15920 T23336 T23338 arg1Of n,3
R15921 T23339 T23335 arg3Of ),(
R16260 T23908 T23909 arg1Of GP,modulated
R16261 T23910 T23911 arg1Of LPS-,and
R16262 T23911 T23909 arg2Of and,modulated
R16263 T23913 T23911 arg2Of binding,and
R16264 T23913 T23912 arg1Of binding,TSST-1-induced
R16265 T23913 T23914 arg1Of binding,to
R16266 T23918 T23914 arg2Of site,to
R16267 T23918 T23915 arg1Of site,a
R16268 T23918 T23916 arg1Of site,new
R16269 T23918 T23917 arg1Of site,NFκB3
R16270 T23918 T23919 arg1Of site,in
R16271 T23922 T23919 arg2Of promoter,in
R16272 T23922 T23920 arg1Of promoter,the
R16273 T23922 T23921 arg1Of promoter,IL-1RA
R16274 T23923 T23924 arg1Of Binding,was
R16275 T23923 T23925 arg2Of Binding,enhanced
R16276 T23925 T23924 arg2Of enhanced,was
R16277 T23925 T23926 arg1Of enhanced,for
R16278 T23925 T23934 arg1Of enhanced,","
R16279 T23925 T23935 arg1Of enhanced,when
R16280 T23929 T23927 arg1Of LPS,GP
R16281 T23929 T23928 arg1Of LPS,+
R16282 T23929 T23930 arg1Of LPS,and
R16283 T23930 T23926 arg2Of and,for
R16284 T23933 T23930 arg2Of TSST-1,and
R16285 T23933 T23931 arg1Of TSST-1,GP
R16286 T23933 T23932 arg1Of TSST-1,+
R16287 T23936 T23935 arg2Of compared,when
R16288 T23936 T23937 arg1Of compared,to
R16289 T23938 T23939 arg1Of LPS,","
R16290 T23939 T23941 arg1Of ",",","
R16291 T23940 T23939 arg2Of TSST-1,","
R16292 T23941 T23943 arg1Of ",",","
R16293 T23942 T23941 arg2Of GP,","
R16294 T23943 T23937 arg2Of ",",to
R16295 T23943 T23949 arg1Of ",",","
R16296 T23943 T23950 arg1Of ",",respectively
R16297 T23945 T23944 arg1Of calc.,GP/LPS
R16298 T23945 T23946 arg1Of calc.,or
R16299 T23946 T23943 arg2Of or,","
R16300 T23948 T23946 arg2Of calc.,or
R16301 T23948 T23947 arg1Of calc.,GP/TSST-1
R16302 T23950 T23951 arg1Of respectively,(
R16303 T23956 T23951 arg2Of 0.05,(
R16304 T23956 T23952 arg1Of 0.05,*
R16305 T23956 T23953 arg1Of 0.05,=
R16306 T23956 T23954 arg1Of 0.05,p
R16307 T23956 T23955 arg1Of 0.05,<
R16308 T23956 T23957 arg1Of 0.05,;
R16309 T23956 T23962 arg1Of 0.05,0.01
R16310 T23960 T23957 arg2Of p,;
R16311 T23960 T23958 arg1Of p,**
R16312 T23960 T23959 arg1Of p,=
R16313 T23960 T23961 arg1Of p,<
R16314 T23963 T23951 arg3Of ),(
R16315 T23966 T23964 arg1Of levels,Medium
R16316 T23966 T23965 arg1Of levels,control
R16317 T23966 T23967 arg1Of levels,were
R16318 T23966 T23968 arg2Of levels,set
R16319 T23966 T23969 arg1Of levels,equal
R16320 T23968 T23967 arg2Of set,were
R16321 T23969 T23968 arg3Of equal,set
R16322 T23969 T23970 arg1Of equal,to
R16323 T23971 T23972 arg1Of 1,±
R16324 T23972 T23970 arg2Of ±,to
R16325 T23972 T23974 arg1Of ±,(
R16326 T23973 T23972 arg2Of SEM,±
R16327 T23975 T23976 arg1Of n,=
R16328 T23976 T23974 arg2Of =,(
R16329 T23977 T23976 arg2Of 6,=
R16330 T23978 T23974 arg3Of ),(
R16331 T23980 T23979 arg1Of binding,DNA
R16332 T23980 T23981 arg1Of binding,was
R16333 T23980 T23982 arg2Of binding,assessed
R16334 T23982 T23981 arg2Of assessed,was
R16335 T23982 T23985 arg1Of assessed,(
R16336 T23984 T23982 arg1Of EMSA,assessed
R16337 T23984 T23983 arg2Of EMSA,by
R16338 T23986 T23985 arg2Of see,(
R16339 T23987 T23986 arg2Of methods,see
R16340 T23988 T23985 arg3Of ),(
R16477 T24266 T24267 arg1Of GP,modulated
R16478 T24270 T24267 arg2Of binding,modulated
R16479 T24270 T24268 arg1Of binding,TSST-1-induced
R16480 T24270 T24269 arg1Of binding,DNA
R16481 T24270 T24271 arg1Of binding,to
R16482 T24275 T24271 arg2Of site,to
R16483 T24275 T24272 arg1Of site,a
R16484 T24275 T24273 arg1Of site,new
R16485 T24275 T24274 arg1Of site,NFATP2/3
R16486 T24275 T24276 arg1Of site,in
R16487 T24279 T24276 arg2Of promoter,in
R16488 T24279 T24277 arg1Of promoter,the
R16489 T24279 T24278 arg1Of promoter,IL-1RA
R16490 T24280 T24281 arg1Of Binding,was
R16491 T24280 T24282 arg2Of Binding,up-regulated
R16492 T24282 T24281 arg2Of up-regulated,was
R16493 T24282 T24283 arg1Of up-regulated,for
R16494 T24282 T24291 arg1Of up-regulated,","
R16495 T24282 T24292 arg1Of up-regulated,when
R16496 T24286 T24284 arg1Of LPS,GP
R16497 T24286 T24285 arg1Of LPS,+
R16498 T24286 T24287 arg1Of LPS,and
R16499 T24287 T24283 arg2Of and,for
R16500 T24290 T24287 arg2Of TSST-1,and
R16501 T24290 T24288 arg1Of TSST-1,GP
R16502 T24290 T24289 arg1Of TSST-1,+
R16503 T24293 T24292 arg2Of compared,when
R16504 T24293 T24294 arg1Of compared,to
R16505 T24293 T24298 arg1Of compared,in
R16506 T24293 T24302 arg1Of compared,","
R16507 T24293 T24303 arg1Of compared,to
R16508 T24294 T24296 arg1Of to,and
R16509 T24294 T24297 arg1Of to,","
R16510 T24295 T24294 arg2Of GP,to
R16511 T24298 T24297 arg2Of in,","
R16512 T24301 T24298 arg2Of case,in
R16513 T24301 T24299 arg1Of case,the
R16514 T24301 T24300 arg1Of case,latter
R16515 T24305 T24306 arg1Of GP,and
R16516 T24306 T24303 arg2Of and,to
R16517 T24306 T24304 arg1Of and,both
R16518 T24306 T24308 arg1Of and,(
R16519 T24307 T24306 arg2Of TSST-1,and
R16520 T24311 T24308 arg2Of p,(
R16521 T24311 T24309 arg1Of p,*
R16522 T24311 T24310 arg1Of p,=
R16523 T24311 T24312 arg1Of p,<
R16524 T24311 T24313 arg1Of p,0.05
R16525 T24314 T24308 arg3Of ),(
R16526 T24316 T24315 arg1Of PBMC,Human
R16527 T24316 T24317 arg1Of PBMC,were
R16528 T24316 T24318 arg2Of PBMC,incubated
R16529 T24318 T24317 arg2Of incubated,were
R16530 T24318 T24319 arg1Of incubated,with
R16531 T24321 T24320 arg1Of control,medium
R16532 T24321 T24322 arg1Of control,","
R16533 T24322 T24324 arg1Of ",",","
R16534 T24323 T24322 arg2Of LPS,","
R16535 T24324 T24326 arg1Of ",",","
R16536 T24325 T24324 arg2Of TSST-1,","
R16537 T24326 T24328 arg1Of ",",","
R16538 T24327 T24326 arg2Of GP,","
R16539 T24328 T24332 arg1Of ",",and
R16540 T24331 T24328 arg2Of TSST-1,","
R16541 T24331 T24329 arg1Of TSST-1,GP
R16542 T24331 T24330 arg1Of TSST-1,+
R16543 T24332 T24319 arg2Of and,with
R16544 T24335 T24332 arg2Of LPS,and
R16545 T24335 T24333 arg1Of LPS,GP
R16546 T24335 T24334 arg1Of LPS,+
R16547 T24335 T24336 arg1Of LPS,for
R16548 T24338 T24336 arg2Of h,for
R16549 T24338 T24337 arg1Of h,1
R16550 T24338 T24339 arg1Of h,at
R16551 T24338 T24349 arg1Of h,to
R16552 T24341 T24340 arg1Of Schematic,37°C.
R16553 T24342 T24339 arg2Of representation,at
R16554 T24342 T24341 arg1Of representation,Schematic
R16555 T24342 T24343 arg1Of representation,of
R16556 T24348 T24343 arg2Of activity,of
R16557 T24348 T24344 arg1Of activity,the
R16558 T24348 T24345 arg1Of activity,elevated
R16559 T24348 T24346 arg1Of activity,NFAT-DNA
R16560 T24348 T24347 arg1Of activity,binding
R16561 T24351 T24349 arg2Of site,to
R16562 T24351 T24350 arg1Of site,the
R16563 T24351 T24352 arg1Of site,in
R16564 T24355 T24352 arg2Of promoter,in
R16565 T24355 T24353 arg1Of promoter,the
R16566 T24355 T24354 arg1Of promoter,IL-1RA
R16567 T24356 T24357 arg1Of Bars,depicting
R16568 T24356 T24367 arg1Of Bars,are
R16569 T24356 T24368 arg2Of Bars,added
R16570 T24360 T24357 arg2Of values,depicting
R16571 T24360 T24358 arg1Of values,the
R16572 T24360 T24359 arg1Of values,theoretical
R16573 T24360 T24361 arg1Of values,for
R16574 T24363 T24362 arg1Of calc.,GP/LPS
R16575 T24363 T24364 arg1Of calc.,and
R16576 T24364 T24361 arg2Of and,for
R16577 T24366 T24364 arg2Of calc.,and
R16578 T24366 T24365 arg1Of calc.,GP/TSST-1
R16579 T24368 T24367 arg2Of added,are
R16580 T24371 T24369 arg1Of levels,Medium
R16581 T24371 T24370 arg1Of levels,control
R16582 T24371 T24372 arg1Of levels,were
R16583 T24371 T24373 arg2Of levels,set
R16584 T24371 T24374 arg1Of levels,equal
R16585 T24373 T24372 arg2Of set,were
R16586 T24374 T24373 arg3Of equal,set
R16587 T24374 T24375 arg1Of equal,to
R16588 T24376 T24377 arg1Of 1,±
R16589 T24377 T24375 arg2Of ±,to
R16590 T24377 T24379 arg1Of ±,(
R16591 T24378 T24377 arg2Of SEM,±
R16592 T24380 T24381 arg1Of n,=
R16593 T24381 T24379 arg2Of =,(
R16594 T24382 T24381 arg2Of 6,=
R16595 T24383 T24379 arg3Of ),(
R16596 T24385 T24384 arg1Of autoradiogram,An
R16597 T24385 T24386 arg1Of autoradiogram,of
R16598 T24385 T24390 arg1Of autoradiogram,is
R16599 T24385 T24391 arg2Of autoradiogram,shown
R16600 T24389 T24386 arg2Of experiment,of
R16601 T24389 T24387 arg1Of experiment,a
R16602 T24389 T24388 arg1Of experiment,representative
R16603 T24391 T24390 arg2Of shown,is
R16604 T24391 T24392 arg1Of shown,in
R16605 T24395 T24392 arg2Of panel,in
R16606 T24395 T24393 arg1Of panel,the
R16607 T24395 T24394 arg1Of panel,lower
R16608 T24395 T24396 arg1Of panel,(
R16609 T24397 T24396 arg2Of lane,(
R16610 T24397 T24398 arg1Of lane,1
R16611 T24397 T24399 arg1Of lane,:
R16612 T24400 T24399 arg2Of water,:
R16613 T24400 T24401 arg1Of water,;
R16614 T24400 T24432 arg1Of water,:
R16615 T24402 T24401 arg2Of lane,;
R16616 T24402 T24403 arg1Of lane,2
R16617 T24402 T24404 arg1Of lane,:
R16618 T24406 T24405 arg1Of control,medium
R16619 T24406 T24407 arg1Of control,;
R16620 T24407 T24404 arg2Of ;,:
R16621 T24407 T24410 arg1Of ;,:
R16622 T24408 T24407 arg2Of lane,;
R16623 T24408 T24409 arg1Of lane,3
R16624 T24411 T24410 arg2Of GP,:
R16625 T24411 T24412 arg1Of GP,;
R16626 T24413 T24412 arg2Of lane,;
R16627 T24413 T24414 arg1Of lane,4
R16628 T24413 T24415 arg1Of lane,:
R16629 T24416 T24415 arg2Of LPS,:
R16630 T24416 T24417 arg1Of LPS,;
R16631 T24416 T24429 arg1Of LPS,;
R16632 T24418 T24417 arg2Of lane,;
R16633 T24418 T24419 arg1Of lane,5
R16634 T24418 T24420 arg1Of lane,:
R16635 T24421 T24420 arg2Of TSST-1,:
R16636 T24421 T24422 arg1Of TSST-1,","
R16637 T24421 T24425 arg1Of TSST-1,:
R16638 T24423 T24422 arg2Of lane,","
R16639 T24423 T24424 arg1Of lane,6
R16640 T24426 T24427 arg1Of GP,+
R16641 T24427 T24425 arg2Of +,:
R16642 T24428 T24427 arg2Of LPS,+
R16643 T24430 T24429 arg2Of lane,;
R16644 T24430 T24431 arg1Of lane,7
R16645 T24433 T24432 arg2Of GP,:
R16646 T24433 T24434 arg1Of GP,+
R16647 T24433 T24435 arg1Of GP,TSST-1
R16648 T24436 T24396 arg3Of ),(
R16893 T24926 T24924 arg2Of ratio,Decreased
R16894 T24926 T24925 arg1Of ratio,IL-1β/IL-1RA
R16895 T24926 T24927 arg1Of ratio,following
R16896 T24926 T24932 arg1Of ratio,compared
R16897 T24927 T24931 arg1Of following,when
R16898 T24930 T24927 arg2Of TSST-1,following
R16899 T24930 T24928 arg1Of TSST-1,GP
R16900 T24930 T24929 arg1Of TSST-1,+
R16901 T24932 T24931 arg2Of compared,when
R16902 T24932 T24933 arg1Of compared,to
R16903 T24934 T24933 arg2Of TSST-1,to
R16904 T24936 T24935 arg1Of course,Time
R16905 T24936 T24937 arg1Of course,(
R16906 T24936 T24941 arg1Of course,of
R16907 T24939 T24937 arg2Of h,(
R16908 T24939 T24938 arg1Of h,48
R16909 T24940 T24937 arg3Of ),(
R16910 T24944 T24941 arg2Of ratio,of
R16911 T24944 T24942 arg1Of ratio,the
R16912 T24944 T24943 arg1Of ratio,IL-1β/IL-1RA
R16913 T24944 T24945 arg1Of ratio,following
R16914 T24946 T24945 arg2Of incubation,following
R16915 T24946 T24947 arg1Of incubation,of
R16916 T24946 T24950 arg1Of incubation,with
R16917 T24949 T24947 arg2Of PBMC,of
R16918 T24949 T24948 arg1Of PBMC,human
R16919 T24951 T24952 arg1Of LPS,","
R16920 T24952 T24954 arg1Of ",",","
R16921 T24953 T24952 arg2Of TSST-1,","
R16922 T24954 T24958 arg1Of ",",","
R16923 T24957 T24954 arg2Of LPS,","
R16924 T24957 T24955 arg1Of LPS,GP
R16925 T24957 T24956 arg1Of LPS,+
R16926 T24958 T24961 arg1Of ",",","
R16927 T24960 T24958 arg2Of calc.,","
R16928 T24960 T24959 arg1Of calc.,GP/LPS
R16929 T24961 T24965 arg1Of ",",or
R16930 T24964 T24961 arg2Of TSST-1,","
R16931 T24964 T24962 arg1Of TSST-1,GP
R16932 T24964 T24963 arg1Of TSST-1,+
R16933 T24965 T24950 arg2Of or,with
R16934 T24967 T24965 arg2Of calc,or
R16935 T24967 T24966 arg1Of calc,GP/TSST-1
R16936 T24968 T24969 arg1Of LPS,and
R16937 T24969 T24974 arg1Of and,resulted
R16938 T24969 T24976 arg1Of and,generating
R16939 T24973 T24969 arg2Of treatments,and
R16940 T24973 T24970 arg1Of treatments,GP
R16941 T24973 T24971 arg1Of treatments,+
R16942 T24973 T24972 arg1Of treatments,LPS
R16943 T24974 T24975 arg1Of resulted,in
R16944 T24976 T24975 arg2Of generating,in
R16945 T24978 T24976 arg2Of IL-1β,generating
R16946 T24978 T24977 arg1Of IL-1β,more
R16947 T24978 T24979 arg1Of IL-1β,than
R16948 T24983 T24980 arg1Of 24,IL-1RA
R16949 T24983 T24981 arg1Of 24,up
R16950 T24983 T24982 arg1Of 24,to
R16951 T24984 T24979 arg2Of h,than
R16952 T24984 T24983 arg1Of h,24
R16953 T24986 T24985 arg2Of comparing,When
R16954 T24987 T24988 arg1Of LPS,or
R16955 T24988 T24986 arg2Of or,comparing
R16956 T24988 T24991 arg1Of or,vs
R16957 T24990 T24988 arg2Of calc.,or
R16958 T24990 T24989 arg1Of calc.,GP/LPS
R16959 T24994 T24991 arg2Of LPS,vs
R16960 T24994 T24992 arg1Of LPS,GP
R16961 T24994 T24993 arg1Of LPS,+
R16962 T24995 T24986 arg1Of we,comparing
R16963 T24995 T24996 arg1Of we,did
R16964 T24995 T24998 arg1Of we,find
R16965 T24998 T24985 arg1Of find,When
R16966 T24998 T24996 arg2Of find,did
R16967 T24998 T24997 arg1Of find,not
R16968 T25000 T24998 arg2Of alterations,find
R16969 T25000 T24999 arg1Of alterations,significant
R16970 T25000 T25001 arg1Of alterations,in
R16971 T25004 T25001 arg2Of ratio,in
R16972 T25004 T25002 arg1Of ratio,the
R16973 T25004 T25003 arg1Of ratio,IL-1β/IL-1RA
R16974 T25004 T25005 arg1Of ratio,over
R16975 T25007 T25005 arg2Of h,over
R16976 T25007 T25006 arg1Of h,48
R16977 T25009 T25008 arg2Of respect,With
R16978 T25009 T25010 arg1Of respect,to
R16979 T25011 T25012 arg1Of TSST-1,or
R16980 T25012 T25010 arg2Of or,to
R16981 T25012 T25015 arg1Of or,vs
R16982 T25014 T25012 arg2Of calc.,or
R16983 T25014 T25013 arg1Of calc.,GP/TSST-1
R16984 T25016 T25015 arg2Of GP,vs
R16985 T25016 T25017 arg1Of GP,+
R16986 T25018 T25008 arg3Of TSST-1,With
R16987 T25019 T25020 arg1Of we,observed
R16988 T25020 T25008 arg1Of observed,With
R16989 T25020 T25027 arg1Of observed,","
R16990 T25020 T25028 arg1Of observed,as
R16992 T25024 T25020 arg2Of action,observed
R16993 T25024 T25021 arg1Of action,a
R16994 T25024 T25022 arg1Of action,pronounced
R16995 T25024 T25023 arg1Of action,anti-inflammatory
R16996 T25024 T25025 arg1Of action,of
R16997 T25026 T25025 arg2Of GP,of
R16998 T25029 T25028 arg2Of demonstrated,as
R17000 T25033 T25032 arg1Of 10–100,about
R17001 T25036 T25029 arg1Of ratio,demonstrated
R17002 T25036 T25030 arg2Of ratio,by
R17003 T25036 T25031 arg1Of ratio,an
R17004 T25036 T25033 arg1Of ratio,10–100
R17012 T25047 T25020 arg3Of production,observed
R17312 T25594 T25595 arg1Of Inhibition,of
R17313 T25597 T25598 arg1Of NFκB,","
R17314 T25598 T25600 arg1Of ",",and
R17315 T25599 T25598 arg2Of NFAT,","
R17316 T25601 T25600 arg2Of NFIL-6,and
R17317 T25603 T25595 arg2Of binding,of
R17318 T25603 T25596 arg1Of binding,GP-induced
R17319 T25603 T25597 arg1Of binding,NFκB
R17320 T25603 T25599 arg1Of binding,NFAT
R17321 T25603 T25601 arg1Of binding,NFIL-6
R17322 T25603 T25602 arg1Of binding,DNA
R17323 T25603 T25604 arg1Of binding,to
R17324 T25607 T25604 arg2Of promoter,to
R17325 T25607 T25605 arg1Of promoter,the
R17326 T25607 T25606 arg1Of promoter,IL-1RA
R17327 T25612 T25610 arg1Of autoradiogram,A
R17328 T25612 T25611 arg1Of autoradiogram,representative
R17329 T25612 T25613 arg1Of autoradiogram,(
R17330 T25612 T25671 arg1Of autoradiogram,as
R17331 T25614 T25615 arg1Of lane,1
R17332 T25614 T25616 arg1Of lane,:
R17333 T25614 T25657 arg1Of lane,:
R17334 T25617 T25616 arg2Of control,:
R17335 T25617 T25618 arg1Of control,","
R17336 T25617 T25621 arg1Of control,:
R17337 T25619 T25618 arg2Of lane,","
R17338 T25619 T25620 arg1Of lane,2
R17339 T25622 T25621 arg2Of GP,:
R17340 T25622 T25623 arg1Of GP,","
R17341 T25622 T25633 arg1Of GP,","
R17342 T25622 T25636 arg1Of GP,:
R17343 T25624 T25625 arg1Of lane,3
R17344 T25624 T25626 arg1Of lane,:
R17345 T25626 T25623 arg2Of :,","
R17346 T25627 T25628 arg1Of GP,+
R17347 T25629 T25628 arg2Of unlabeled,+
R17348 T25632 T25626 arg2Of oligo,:
R17349 T25632 T25627 arg1Of oligo,GP
R17350 T25632 T25629 arg1Of oligo,unlabeled
R17351 T25632 T25630 arg2Of oligo,mutated
R17352 T25632 T25631 arg1Of oligo,NFATP2/3
R17353 T25634 T25633 arg2Of lane,","
R17354 T25634 T25635 arg1Of lane,4
R17355 T25639 T25636 arg2Of CAPE,:
R17356 T25639 T25637 arg1Of CAPE,GP
R17357 T25639 T25638 arg1Of CAPE,+
R17358 T25639 T25640 arg1Of CAPE,","
R17359 T25639 T25647 arg1Of CAPE,","
R17360 T25639 T25650 arg1Of CAPE,:
R17361 T25641 T25640 arg2Of lane,","
R17362 T25641 T25642 arg1Of lane,5
R17363 T25641 T25643 arg1Of lane,:
R17364 T25641 T25644 arg1Of lane,GP
R17365 T25646 T25644 arg2Of CyA,GP
R17366 T25646 T25645 arg1Of CyA,+
R17367 T25648 T25647 arg2Of lane,","
R17368 T25648 T25649 arg1Of lane,6
R17369 T25653 T25650 arg2Of CHX,:
R17370 T25653 T25651 arg1Of CHX,GP
R17371 T25653 T25652 arg1Of CHX,+
R17372 T25653 T25654 arg1Of CHX,","
R17373 T25655 T25654 arg2Of lane,","
R17374 T25655 T25656 arg1Of lane,7
R17375 T25657 T25613 arg2Of :,(
R17376 T25657 T25666 arg1Of :,:
R17377 T25662 T25657 arg2Of oligo,:
R17378 T25662 T25658 arg1Of oligo,GP
R17379 T25662 T25659 arg1Of oligo,+
R17380 T25662 T25660 arg1Of oligo,unlabeled
R17381 T25662 T25661 arg1Of oligo,NFATP2/3
R17382 T25662 T25663 arg1Of oligo,","
R17383 T25664 T25663 arg2Of lane,","
R17384 T25664 T25665 arg1Of lane,8
R17385 T25667 T25666 arg2Of water,:
R17386 T25668 T25613 arg3Of ),(
R17387 T25671 T25669 arg1Of as,as
R17388 T25671 T25670 arg1Of as,well
R17389 T25671 T25691 arg1Of as,is
R17390 T25671 T25692 arg2Of as,displayed
R17391 T25674 T25671 arg2Of summary,as
R17392 T25674 T25672 arg1Of summary,a
R17393 T25674 T25673 arg1Of summary,graphical
R17394 T25674 T25675 arg1Of summary,for
R17395 T25678 T25675 arg2Of site,for
R17396 T25678 T25676 arg1Of site,the
R17397 T25678 T25677 arg1Of site,NFATP2/3
R17398 T25678 T25679 arg1Of site,","
R17399 T25680 T25679 arg2Of depicting,","
R17400 T25680 T25687 arg1Of depicting,when
R17401 T25682 T25680 arg2Of decrease,depicting
R17402 T25682 T25681 arg1Of decrease,a
R17403 T25682 T25683 arg1Of decrease,in
R17404 T25684 T25683 arg2Of binding,in
R17405 T25684 T25685 arg1Of binding,following
R17406 T25686 T25685 arg2Of inhibition,following
R17407 T25688 T25687 arg2Of compared,when
R17408 T25688 T25689 arg1Of compared,to
R17409 T25690 T25689 arg2Of GP,to
R17410 T25692 T25608 arg1Of displayed,A
R17411 T25692 T25609 arg1Of displayed,","
R17412 T25692 T25691 arg2Of displayed,is
R17413 T25692 T25693 arg1Of displayed,(
R17414 T25696 T25693 arg2Of p,(
R17415 T25696 T25694 arg1Of p,*
R17416 T25696 T25695 arg1Of p,=
R17417 T25696 T25697 arg1Of p,<
R17418 T25696 T25698 arg1Of p,0.05
R17419 T25699 T25693 arg3Of ),(
R17420 T25700 T25701 arg1Of Data,are
R17421 T25700 T25702 arg2Of Data,shown
R17422 T25702 T25701 arg2Of shown,are
R17423 T25702 T25703 arg1Of shown,as
R17424 T25706 T25703 arg2Of SEM,as
R17425 T25706 T25704 arg1Of SEM,mean
R17426 T25706 T25705 arg1Of SEM,±
R17427 T25706 T25707 arg1Of SEM,(
R17428 T25708 T25707 arg2Of n,(
R17429 T25708 T25709 arg1Of n,=
R17430 T25708 T25710 arg1Of n,4
R17431 T25711 T25707 arg3Of ),(
R17432 T25712 T25713 arg1Of B,","
R17433 T25713 T25717 arg1Of ",",","
R17434 T25714 T25713 arg2Of Inhibition,","
R17435 T25714 T25715 arg1Of Inhibition,of
R17436 T25716 T25715 arg2Of NFκB,of
R17437 T25717 T25719 arg1Of ",",and
R17438 T25718 T25717 arg2Of NFAT,","
R17439 T25719 T25721 arg1Of and,resulted
R17440 T25720 T25719 arg2Of NFIL-6,and
R17441 T25721 T25722 arg1Of resulted,in
R17442 T25721 T25726 arg1Of resulted,following
R17443 T25721 T25732 arg1Of resulted,compared
R17444 T25725 T25722 arg2Of mRNA,in
R17445 T25725 T25723 arg2Of mRNA,decreased
R17446 T25725 T25724 arg1Of mRNA,IL-1RA
R17447 T25727 T25728 arg1Of CHX,","
R17448 T25728 T25730 arg1Of ",",or
R17449 T25729 T25728 arg2Of CAPE,","
R17450 T25730 T25726 arg2Of or,following
R17451 T25731 T25730 arg2Of CyA,or
R17452 T25733 T25732 arg2Of to,compared
R17453 T25734 T25733 arg2Of GP,to
R17454 T25735 T25736 arg1Of GAPDH,is
R17455 T25735 T25737 arg2Of GAPDH,used
R17456 T25737 T25736 arg2Of used,is
R17457 T25737 T25738 arg1Of used,as
R17458 T25740 T25738 arg2Of control,as
R17459 T25740 T25739 arg1Of control,housekeeping
R17460 T25740 T25741 arg1Of control,(
R17461 T25743 T25741 arg2Of gel,(
R17462 T25743 T25742 arg1Of gel,representative
R17463 T25743 T25744 arg1Of gel,","
R17464 T25745 T25744 arg2Of n,","
R17465 T25745 T25746 arg1Of n,=
R17466 T25745 T25747 arg1Of n,4
R17467 T25748 T25741 arg3Of ),(
R17468 T25749 T25750 arg1Of C,","
R17469 T25750 T25754 arg1Of ",",","
R17470 T25751 T25750 arg2Of Inhibition,","
R17471 T25751 T25752 arg1Of Inhibition,of
R17472 T25753 T25752 arg2Of NFκB,of
R17473 T25754 T25756 arg1Of ",",and
R17474 T25755 T25754 arg2Of NFAT,","
R17475 T25756 T25759 arg1Of and,reduced
R17476 T25756 T25776 arg1Of and,compared
R17477 T25757 T25756 arg2Of NFIL-6,and
R17478 T25759 T25758 arg1Of reduced,significantly
R17479 T25759 T25767 arg1Of reduced,following
R17480 T25759 T25775 arg1Of reduced,when
R17481 T25761 T25759 arg2Of production,reduced
R17482 T25761 T25760 arg1Of production,the
R17483 T25761 T25762 arg1Of production,of
R17484 T25761 T25764 arg1Of production,by
R17485 T25763 T25762 arg2Of IL-1RA,of
R17486 T25766 T25764 arg2Of PBMC,by
R17487 T25766 T25765 arg1Of PBMC,human
R17488 T25768 T25767 arg2Of treatment,following
R17489 T25768 T25769 arg1Of treatment,with
R17490 T25770 T25771 arg1Of CHX,","
R17491 T25771 T25773 arg1Of ",",or
R17492 T25772 T25771 arg2Of CAPE,","
R17493 T25773 T25769 arg2Of or,with
R17494 T25774 T25773 arg2Of CyA,or
R17495 T25776 T25775 arg2Of compared,when
R17496 T25776 T25777 arg1Of compared,to
R17497 T25778 T25777 arg2Of GP,to
R17498 T25778 T25779 arg1Of GP,(
R17499 T25784 T25779 arg2Of 0.05,(
R17500 T25784 T25780 arg1Of 0.05,*
R17501 T25784 T25781 arg1Of 0.05,=
R17502 T25784 T25782 arg1Of 0.05,p
R17503 T25784 T25783 arg1Of 0.05,<
R17504 T25784 T25785 arg1Of 0.05,;
R17505 T25784 T25790 arg1Of 0.05,0.01
R17506 T25788 T25785 arg2Of p,;
R17507 T25788 T25786 arg1Of p,**
R17508 T25788 T25787 arg1Of p,=
R17509 T25788 T25789 arg1Of p,<
R17510 T25791 T25779 arg3Of ),(
R17511 T25792 T25793 arg1Of Data,are
R17512 T25792 T25794 arg2Of Data,shown
R17513 T25794 T25793 arg2Of shown,are
R17514 T25794 T25795 arg1Of shown,as
R17515 T25798 T25795 arg2Of SEM,as
R17516 T25798 T25796 arg1Of SEM,mean
R17517 T25798 T25797 arg1Of SEM,±
R17518 T25798 T25799 arg1Of SEM,(
R17519 T25800 T25799 arg2Of n,(
R17520 T25800 T25801 arg1Of n,=
R17521 T25800 T25802 arg1Of n,3
R17522 T25803 T25799 arg3Of ),(
R17823 T26165 T26164 arg1Of strand,Sense
R17824 T26165 T26166 arg1Of strand,of
R17825 T26167 T26166 arg2Of oligonucleotides,of
R17826 T26167 T26168 arg2Of oligonucleotides,used
R17827 T26168 T26169 arg1Of used,in
R17828 T26170 T26169 arg2Of EMSAs,in
R17837 T26192 T26193 arg1Of Cartoon,of
R17838 T26196 T26193 arg2Of strand,of
R17839 T26196 T26194 arg1Of strand,the
R17840 T26196 T26195 arg1Of strand,sense
R17841 T26196 T26197 arg1Of strand,of
R17842 T26200 T26197 arg2Of promoter,of
R17843 T26200 T26198 arg1Of promoter,the
R17844 T26200 T26199 arg1Of promoter,IL-1RA
R17845 T26202 T26201 arg1Of locations,Relative
R17846 T26202 T26203 arg1Of locations,of
R17847 T26202 T26213 arg2Of locations,described
R17848 T26206 T26203 arg2Of LRE-1,of
R17849 T26206 T26204 arg1Of LRE-1,previously
R17850 T26206 T26205 arg2Of LRE-1,(
R17851 T26206 T26208 arg1Of LRE-1,[
R17852 T26207 T26205 arg3Of ),(
R17853 T26209 T26208 arg2Of 30-33,[
R17854 T26210 T26208 arg3Of ],[
R17855 T26213 T26211 arg1Of described,and
R17856 T26213 T26212 arg1Of described,newly
R17857 T26213 T26214 arg1Of described,(
R17858 T26213 T26217 arg1Of described,","
R17859 T26215 T26214 arg2Of boxed,(
R17860 T26216 T26214 arg3Of ),(
R17861 T26220 T26219 arg2Of black,(
R17862 T26221 T26219 arg3Of ),(
R17863 T26223 T26224 arg1Of negatively,(
R17864 T26225 T26224 arg2Of gray,(
R17865 T26226 T26224 arg3Of ),(
R17866 T26227 T26222 arg1Of regulatory,and
R17867 T26227 T26223 arg1Of regulatory,negatively
R17868 T26231 T26219 arg1Of sites,(
R17869 T26231 T26227 arg1Of sites,regulatory
R17870 T26231 T26228 arg1Of sites,transcription
R17871 T26231 T26229 arg1Of sites,factor
R17872 T26231 T26230 arg1Of sites,binding
R17873 T26231 T26232 arg1Of sites,are
R17874 T26231 T26233 arg2Of sites,depicted
R17875 T26233 T26213 arg3Of depicted,described
R17876 T26233 T26218 arg1Of depicted,positively
R17877 T26233 T26232 arg2Of depicted,are
R587 T1450 T1448 arg3Of ],[
R588 T1453 T1454 arg1Of it,has
R589 T1453 T1455 arg1Of it,been
R590 T1453 T1456 arg2Of it,shown
R591 T1456 T1451 arg1Of shown,Similarly
R592 T1456 T1452 arg1Of shown,","
R593 T1456 T1454 arg2Of shown,has
R594 T1456 T1455 arg2Of shown,been
R595 T1458 T1459 arg1Of β-1→3-D-glucans,activate
R596 T1459 T1456 arg3Of activate,shown
R597 T1459 T1457 arg1Of activate,that
R598 T1459 T1461 arg1Of activate,in
R599 T1459 T1471 arg1Of activate,in
R600 T1459 T1479 arg1Of activate,in
R601 T1459 T1483 arg1Of activate,without
R602 T1460 T1459 arg2Of NFκB,activate
R603 T1461 T1470 arg1Of in,and
R604 T1466 T1461 arg2Of line,in
R605 T1466 T1462 arg1Of line,a
R606 T1466 T1463 arg1Of line,human
R607 T1466 T1464 arg1Of line,monocyte-like
R608 T1466 T1465 arg1Of line,cell
R609 T1466 T1467 arg1Of line,[
R610 T1468 T1467 arg2Of 15,[
R611 T1469 T1467 arg3Of ],[
R612 T1470 T1478 arg1Of and,","
R613 T1471 T1470 arg2Of in,and
R614 T1474 T1471 arg2Of neutrophils,in
R615 T1474 T1472 arg1Of neutrophils,human
R616 T1474 T1473 arg1Of neutrophils,polymorphonuclear
R617 T1474 T1475 arg1Of neutrophils,(
R618 T1476 T1475 arg2Of PMN,(
R619 T1477 T1475 arg3Of ),(
R620 T1479 T1478 arg2Of in,","
R621 T1482 T1479 arg2Of case,in
R622 T1482 T1480 arg1Of case,the
R623 T1482 T1481 arg1Of case,latter
R624 T1484 T1483 arg2Of secretion,without
R625 T1484 T1485 arg1Of secretion,of
R626 T1487 T1485 arg2Of cytokines,of
R627 T1487 T1486 arg1Of cytokines,pro-inflammatory
R628 T1487 T1488 arg1Of cytokines,(
R629 T1487 T1495 arg1Of cytokines,[
R630 T1489 T1488 arg2Of IL-1,(
R631 T1489 T1490 arg1Of IL-1,","
R632 T1489 T1492 arg1Of IL-1,","
R633 T1491 T1490 arg2Of IL-6,","
R634 T1493 T1492 arg2Of TNFα,","
R635 T1494 T1488 arg3Of ),(
R636 T1496 T1495 arg2Of 16,[
R637 T1497 T1495 arg3Of ],[
R638 T1499 T1498 arg1Of study,One
R639 T1499 T1500 arg1Of study,proposed
R640 T1503 T1504 arg1Of production,of
R641 T1503 T1509 arg1Of production,but
R642 T1507 T1504 arg2Of IL-1RA,of
R643 T1507 T1505 arg1Of IL-1RA,the
R644 T1507 T1506 arg1Of IL-1RA,anti-inflammatory
R645 T1509 T1502 arg1Of but,the
R646 T1509 T1508 arg1Of but,","
R647 T1509 T1510 arg1Of but,not
R648 T1509 T1512 arg1Of but,by
R649 T1509 T1515 arg1Of but,may
R650 T1509 T1516 arg1Of but,be
R651 T1511 T1509 arg2Of IL-1,but
R652 T1514 T1512 arg2Of monocytes,by
R653 T1514 T1513 arg1Of monocytes,human
R654 T1516 T1500 arg2Of be,proposed
R655 T1516 T1501 arg1Of be,that
R656 T1516 T1515 arg2Of be,may
R657 T1519 T1518 arg1Of protective,potentially
R658 T1520 T1516 arg2Of mechanism,be
R659 T1520 T1517 arg1Of mechanism,a
R660 T1520 T1519 arg1Of mechanism,protective
R661 T1520 T1521 arg2Of mechanism,induced
R662 T1521 T1524 arg1Of induced,[
R663 T1523 T1521 arg1Of β-1→3-D-glucan,induced
R664 T1523 T1522 arg2Of β-1→3-D-glucan,by
R665 T1525 T1524 arg2Of 17,[
R666 T1526 T1524 arg3Of ],[
R667 T1529 T1527 arg1Of investigations,Three
R668 T1529 T1528 arg1Of investigations,other
R669 T1529 T1530 arg1Of investigations,have
R670 T1529 T1531 arg1Of investigations,reported
R671 T1531 T1530 arg2Of reported,have
R672 T1534 T1533 arg1Of leukocytes,human
R673 T1534 T1535 arg1Of leukocytes,and
R674 T1535 T1540 arg1Of and,produce
R675 T1539 T1535 arg2Of cells,and
R676 T1539 T1536 arg1Of cells,human
R677 T1539 T1537 arg1Of cells,vascular
R678 T1539 T1538 arg1Of cells,endothelial
R679 T1540 T1531 arg2Of produce,reported
R680 T1540 T1532 arg1Of produce,that
R681 T1540 T1542 arg1Of produce,in
R682 T1541 T1540 arg2Of IL-8,produce
R683 T1543 T1544 modOf response,to
R684 T1543 T1549 arg1Of response,or
R685 T1545 T1544 arg1Of zymosan,to
R686 T1545 T1546 arg1Of zymosan,[
R687 T1547 T1546 arg2Of 18,[
R688 T1548 T1546 arg3Of ],[
R689 T1549 T1542 arg2Of or,in
R690 T1552 T1549 arg2Of β-1→3-D-glucan,or
R691 T1552 T1550 arg1Of β-1→3-D-glucan,a
R692 T1552 T1551 arg1Of β-1→3-D-glucan,water-soluble
R693 T1552 T1553 arg1Of β-1→3-D-glucan,[
R694 T1554 T1553 arg2Of "6,19",[
R695 T1555 T1553 arg3Of ],[
R696 T1557 T1556 arg2Of addition,In
R697 T1559 T1560 arg1Of β-1→3-D-glucans,seem
R698 T1559 T1562 arg1Of β-1→3-D-glucans,be
R699 T1559 T1563 arg1Of β-1→3-D-glucans,able
R700 T1559 T1565 arg1Of β-1→3-D-glucans,modify
R701 T1560 T1556 arg1Of seem,In
R702 T1560 T1558 arg1Of seem,","
R703 T1562 T1560 arg2Of be,seem
R704 T1562 T1561 arg1Of be,to
R705 T1563 T1562 arg2Of able,be
R706 T1565 T1563 arg2Of modify,able
R707 T1565 T1564 arg1Of modify,to
R708 T1567 T1565 arg2Of response,modify
R709 T1567 T1566 arg1Of response,the
R710 T1567 T1568 arg1Of response,to
R711 T1570 T1569 arg1Of stimuli,pro-inflammatory
R712 T1570 T1571 arg1Of stimuli,or
R713 T1571 T1568 arg2Of or,to
R714 T1573 T1571 arg2Of sepsis,or
R715 T1573 T1572 arg1Of sepsis,even
R716 T1579 T1574 arg2Of model,In
R717 T1579 T1575 arg1Of model,a
R718 T1579 T1576 arg1Of model,murine
R719 T1579 T1577 arg1Of model,polymicrobial
R720 T1579 T1578 arg1Of model,sepsis
R721 T1583 T1582 arg2Of 20,[
R722 T1584 T1582 arg3Of ],[
R723 T1585 T1581 arg1Of treatment,β-1→3-D-glucan
R724 T1585 T1582 arg1Of treatment,[
R725 T1585 T1586 arg1Of treatment,resulted
R726 T1586 T1574 arg1Of resulted,In
R727 T1586 T1580 arg1Of resulted,","
R728 T1586 T1587 arg1Of resulted,in
R729 T1590 T1588 arg2Of morbidity,decreased
R730 T1590 T1589 arg1Of morbidity,septic
R731 T1590 T1591 arg1Of morbidity,and
R732 T1591 T1587 arg2Of and,in
R733 T1591 T1593 arg2Of and,mediated
R734 T1592 T1591 arg2Of mortality,and
R735 T1593 T1594 arg1Of mediated,via
R736 T1595 T1594 arg2Of inhibition,via
R737 T1595 T1596 arg1Of inhibition,of
R738 T1597 T1598 arg1Of NFκB,and
R739 T1598 T1596 arg2Of and,of
R740 T1598 T1600 arg1Of and,of
R741 T1599 T1598 arg2Of stimulation,and
R742 T1604 T1603 arg2Of PI3K,(
R743 T1605 T1603 arg3Of ),(
R744 T1606 T1600 arg2Of pathway,of
R745 T1606 T1601 arg1Of pathway,the
R746 T1606 T1602 arg1Of pathway,phosphoinositide-3-kinase
R747 T1606 T1603 arg1Of pathway,(
R748 T1606 T1607 arg1Of pathway,[
R749 T1608 T1607 arg2Of "21,22",[
R750 T1609 T1607 arg3Of ],[
R751 T1614 T1610 arg1Of studies,These
R752 T1614 T1611 arg1Of studies,and
R753 T1614 T1612 arg1Of studies,other
R754 T1614 T1613 arg1Of studies,animal
R755 T1614 T1615 arg1Of studies,[
R756 T1614 T1620 arg1Of studies,as
R757 T1616 T1615 arg2Of "23,24",[
R758 T1617 T1615 arg3Of ],[
R759 T1620 T1618 arg1Of as,as
R760 T1620 T1619 arg1Of as,well
R761 T1620 T1627 arg1Of as,support
R762 T1623 T1620 arg2Of trial,as
R763 T1623 T1621 arg1Of trial,a
R764 T1623 T1622 arg1Of trial,clinical
R765 T1623 T1624 arg1Of trial,[
R766 T1625 T1624 arg2Of 25,[
R767 T1626 T1624 arg3Of ],[
R768 T1630 T1627 arg2Of role,support
R769 T1630 T1628 arg1Of role,a
R770 T1630 T1629 arg1Of role,protective
R771 T1630 T1631 arg1Of role,of
R772 T1630 T1633 arg1Of role,in
R773 T1632 T1631 arg2Of β-1→3-D-glucan,of
R774 T1636 T1633 arg2Of conditions,in
R775 T1636 T1634 arg1Of conditions,certain
R776 T1636 T1635 arg1Of conditions,pro-inflammatory
R777 T1638 T1637 arg1Of mechanisms,The
R778 T1638 T1639 arg1Of mechanisms,underlying
R779 T1638 T1645 arg1Of mechanisms,are
R780 T1638 T1648 arg2Of mechanisms,resolved
R781 T1642 T1639 arg2Of effects,underlying
R782 T1642 T1640 arg1Of effects,these
R783 T1642 T1641 arg1Of effects,beneficial
R784 T1642 T1643 arg1Of effects,of
R785 T1644 T1643 arg2Of β-1→3-D-glucan,of
R786 T1647 T1646 arg1Of partially,only
R787 T1648 T1645 arg2Of resolved,are
R788 T1648 T1647 arg1Of resolved,partially
R789 T1648 T1649 arg1Of resolved,","
R790 T1648 T1651 arg1Of resolved,in
R791 T1651 T1650 arg1Of in,especially
R792 T1652 T1651 arg2Of humans,in
R793 T1656 T1655 arg1Of aim,the
R794 T1656 T1657 arg1Of aim,of
R795 T1656 T1660 arg1Of aim,was
R796 T1659 T1657 arg2Of study,of
R797 T1659 T1658 arg1Of study,this
R798 T1660 T1653 arg1Of was,Thus
R799 T1660 T1654 arg1Of was,","
R800 T1662 T1660 arg2Of elucidate,was
R801 T1662 T1661 arg1Of elucidate,to
R802 T1662 T1675 arg1Of elucidate,with
R803 T1663 T1664 arg1Of molecular,and
R804 T1665 T1664 arg2Of cellular,and
R805 T1666 T1662 arg2Of mechanisms,elucidate
R806 T1666 T1663 arg1Of mechanisms,molecular
R807 T1666 T1665 arg1Of mechanisms,cellular
R808 T1666 T1667 arg1Of mechanisms,of
R809 T1666 T1669 arg1Of mechanisms,on
R810 T1668 T1667 arg2Of β-1→3-D-glucans,of
R811 T1671 T1669 arg2Of leukocytes,on
R812 T1671 T1670 arg1Of leukocytes,human
R813 T1671 T1672 arg1Of leukocytes,in
R814 T1674 T1672 arg2Of conditions,in
R815 T1674 T1673 arg1Of conditions,pro-inflammatory
R816 T1677 T1675 arg2Of emphasis,with
R817 T1677 T1676 arg1Of emphasis,special
R818 T1677 T1678 arg1Of emphasis,on
R819 T1681 T1679 arg1Of profile,the
R820 T1681 T1680 arg1Of profile,cytokine
R821 T1681 T1682 arg1Of profile,and
R822 T1682 T1678 arg2Of and,on
R823 T1685 T1682 arg2Of regulation,and
R824 T1685 T1683 arg1Of regulation,its
R825 T1685 T1684 arg1Of regulation,transcriptional
R826 T1688 T1686 arg2Of purpose,For
R827 T1688 T1687 arg1Of purpose,this
R828 T1693 T1690 arg1Of cells,peripheral
R829 T1693 T1691 arg1Of cells,blood
R830 T1693 T1692 arg1Of cells,mononuclear
R831 T1693 T1694 arg1Of cells,(
R832 T1693 T1697 arg1Of cells,were
R833 T1693 T1698 arg2Of cells,exposed
R834 T1695 T1694 arg2Of PBMC,(
R835 T1696 T1694 arg3Of ),(
R836 T1698 T1686 arg1Of exposed,For
R837 T1698 T1689 arg1Of exposed,","
R838 T1698 T1697 arg2Of exposed,were
R839 T1698 T1699 arg1Of exposed,to
R840 T1698 T1713 arg1Of exposed,","
R841 T1698 T1714 arg1Of exposed,alone
R842 T1698 T1716 arg1Of exposed,simultaneously
R843 T1698 T1717 arg1Of exposed,with
R844 T1702 T1699 arg2Of β-1→3-D-glucan,to
R845 T1702 T1700 arg1Of β-1→3-D-glucan,a
R846 T1702 T1701 arg1Of β-1→3-D-glucan,well-defined
R847 T1702 T1703 arg1Of β-1→3-D-glucan,","
R848 T1706 T1703 arg2Of phosphate,","
R849 T1706 T1704 arg1Of phosphate,i.e.
R850 T1706 T1705 arg1Of phosphate,glucan
R851 T1706 T1707 arg1Of phosphate,(
R852 T1706 T1710 arg1Of phosphate,[
R853 T1708 T1707 arg2Of GP,(
R854 T1709 T1707 arg3Of ),(
R855 T1711 T1710 arg2Of "20,26",[
R856 T1712 T1710 arg3Of ],[
R857 T1714 T1715 arg1Of alone,or
R858 T1716 T1715 arg2Of simultaneously,or
R859 T1718 T1719 arg1Of LPS,from
R860 T1718 T1722 arg1Of LPS,or
R861 T1721 T1719 arg2Of bacteria,from
R862 T1721 T1720 arg1Of bacteria,gram-negative
R863 T1722 T1717 arg2Of or,with
R864 T1725 T1722 arg2Of TSST-1,or
R865 T1725 T1723 arg1Of TSST-1,the
R866 T1725 T1724 arg1Of TSST-1,superantigen
R867 T1725 T1726 arg1Of TSST-1,from
R868 T1728 T1726 arg2Of bacteria,from
R869 T1728 T1727 arg1Of bacteria,gram-positive
R870 T1730 T1729 arg1Of 48,over
R871 T1731 T1717 arg3Of h,with
R872 T1731 T1730 arg1Of h,48
R873 T1732 T1733 arg1Of Because,of
R874 T1736 T1732 arg2Of effect,Because
R875 T1736 T1734 arg1Of effect,the
R876 T1736 T1735 arg1Of effect,potential
R877 T1736 T1737 arg1Of effect,of
R878 T1736 T1739 arg1Of effect,on
R879 T1738 T1737 arg2Of β-1→3-D-glucan,of
R880 T1741 T1739 arg2Of production,on
R881 T1741 T1740 arg1Of production,cytokine
R882 T1741 T1742 arg1Of production,[
R883 T1743 T1742 arg2Of "12,16-19",[
R884 T1744 T1742 arg3Of ],[
R885 T1746 T1747 arg1Of TNFα,","
R886 T1747 T1749 arg1Of ",",","
R887 T1748 T1747 arg2Of IL-1β,","
R888 T1749 T1751 arg1Of ",",","
R889 T1750 T1749 arg2Of IL-6,","
R890 T1751 T1753 arg1Of ",",and
R891 T1752 T1751 arg2Of IL-8,","
R892 T1753 T1755 arg1Of and,were
R893 T1753 T1756 arg2Of and,measured
R894 T1754 T1753 arg2Of IL-1RA,and
R895 T1756 T1732 arg1Of measured,Because
R896 T1756 T1745 arg1Of measured,","
R897 T1756 T1755 arg2Of measured,were
R898 T1756 T1758 arg1Of measured,well
R899 T1756 T1759 arg1Of measured,as
R900 T1758 T1757 arg1Of well,as
R901 T1760 T1761 arg1Of IFNγ,","
R902 T1761 T1763 arg1Of ",",","
R903 T1762 T1761 arg2Of IL-2,","
R904 T1763 T1765 arg1Of ",",","
R905 T1764 T1763 arg2Of IL-4,","
R906 T1765 T1767 arg1Of ",",","
R907 T1766 T1765 arg2Of IL-10,","
R908 T1767 T1769 arg1Of ",",and
R909 T1768 T1767 arg2Of IL-12,","
R910 T1769 T1759 arg2Of and,as
R911 T1770 T1769 arg2Of TGFβ1,and
R912 T1775 T1773 arg1Of sites,four
R913 T1775 T1774 arg1Of sites,NFκB
R914 T1775 T1776 arg1Of sites,from
R915 T1775 T1780 arg1Of sites,(
R916 T1775 T1790 arg1Of sites,[
R917 T1775 T1793 arg1Of sites,","
R918 T1775 T1805 arg1Of sites,","
R919 T1775 T1819 arg1Of sites,and
R920 T1779 T1776 arg2Of promoter,from
R921 T1779 T1777 arg1Of promoter,the
R922 T1779 T1778 arg1Of promoter,TNFα
R923 T1782 T1780 arg2Of consensus,(
R924 T1782 T1781 arg1Of consensus,κ
R925 T1782 T1783 arg1Of consensus,","
R926 T1782 T1785 arg1Of consensus,","
R927 T1782 T1787 arg1Of consensus,","
R928 T1784 T1783 arg2Of κ1,","
R929 T1786 T1785 arg2Of κ2,","
R930 T1788 T1787 arg2Of κ3,","
R931 T1789 T1780 arg3Of ),(
R932 T1791 T1790 arg2Of 27,[
R933 T1792 T1790 arg3Of ],[
R934 T1797 T1793 arg2Of site,","
R935 T1797 T1794 arg1Of site,a
R936 T1797 T1795 arg1Of site,κ
R937 T1797 T1796 arg1Of site,consensus
R938 T1797 T1798 arg1Of site,from
R939 T1801 T1798 arg2Of promoter,from
R940 T1801 T1799 arg1Of promoter,the
R941 T1801 T1800 arg1Of promoter,IL-8
R942 T1801 T1802 arg1Of promoter,[
R943 T1803 T1802 arg2Of 28,[
R944 T1804 T1802 arg3Of ],[
R945 T1808 T1805 arg2Of site,","
R946 T1808 T1806 arg1Of site,an
R947 T1808 T1807 arg1Of site,NFAT
R948 T1808 T1809 arg1Of site,from
R949 T1812 T1809 arg2Of promoter,from
R950 T1812 T1810 arg1Of promoter,the
R951 T1812 T1811 arg1Of promoter,IFNγ
R952 T1812 T1813 arg1Of promoter,(
R953 T1812 T1816 arg1Of promoter,[
R954 T1814 T1813 arg2Of ATP2,(
R955 T1815 T1813 arg3Of ),(
R956 T1817 T1816 arg2Of 29,[
R957 T1818 T1816 arg3Of ],[
R958 T1819 T1831 arg1Of and,were
R959 T1819 T1832 arg2Of and,examined
R960 T1823 T1819 arg2Of site,and
R961 T1823 T1820 arg1Of site,a
R962 T1823 T1821 arg1Of site,consensus
R963 T1823 T1822 arg1Of site,NFIL-6
R964 T1823 T1824 arg1Of site,from
R965 T1827 T1824 arg2Of promoter,from
R966 T1827 T1825 arg1Of promoter,the
R967 T1827 T1826 arg1Of promoter,IL-6
R968 T1827 T1828 arg1Of promoter,[
R969 T1829 T1828 arg2Of 13,[
R970 T1830 T1828 arg3Of ],[
R971 T1832 T1771 arg1Of examined,Correspondingly
R972 T1832 T1772 arg1Of examined,","
R973 T1832 T1831 arg2Of examined,were
R974 T1833 T1834 arg1Of Because,of
R975 T1837 T1833 arg2Of role,Because
R976 T1837 T1835 arg1Of role,the
R977 T1837 T1836 arg1Of role,anti-inflammatory
R978 T1837 T1838 arg1Of role,of
R979 T1839 T1838 arg2Of IL-1RA,of
R980 T1841 T1842 arg1Of we,focused
R981 T1842 T1833 arg1Of focused,Because
R982 T1842 T1840 arg1Of focused,","
R983 T1842 T1843 arg1Of focused,on
R984 T1844 T1843 arg2Of binding,on
R985 T1844 T1845 arg1Of binding,of
R986 T1844 T1848 arg1Of binding,to
R987 T1847 T1845 arg2Of factors,of
R988 T1847 T1846 arg1Of factors,transcription
R989 T1851 T1848 arg2Of promoter,to
R990 T1851 T1849 arg1Of promoter,the
R991 T1851 T1850 arg1Of promoter,IL-1RA
R992 T1854 T1853 arg1Of element,inhibitory
R993 T1854 T1855 arg1Of element,and
R994 T1855 T1852 arg1Of and,An
R995 T1855 T1871 arg1Of and,","
R996 T1855 T1872 arg1Of and,including
R997 T1855 T1880 arg1Of and,have
R998 T1855 T1881 arg1Of and,been
R999 T1855 T1882 arg2Of and,characterized
R1000 T1859 T1855 arg2Of elements,and
R1001 T1859 T1856 arg1Of elements,three
R1002 T1859 T1857 arg1Of elements,positive-acting
R1003 T1859 T1858 arg1Of elements,LPS-response
R1004 T1859 T1860 arg1Of elements,(
R1005 T1859 T1867 arg1Of elements,in
R1006 T1861 T1862 arg1Of LRE-1,","
R1007 T1862 T1864 arg1Of ",",and
R1008 T1863 T1862 arg2Of LRE-2,","
R1009 T1864 T1860 arg2Of and,(
R1010 T1865 T1864 arg2Of LRE-3,and
R1011 T1866 T1860 arg3Of ),(
R1012 T1870 T1867 arg2Of promoter,in
R1013 T1870 T1868 arg1Of promoter,the
R1014 T1870 T1869 arg1Of promoter,IL-1RA
R1015 T1873 T1874 arg1Of NFκB,","
R1016 T1874 T1876 arg1Of ",",and
R1017 T1875 T1874 arg2Of PU.1,","
R1018 T1877 T1876 arg2Of NFIL-6,and
R1019 T1878 T1872 arg2Of sites,including
R1020 T1878 T1873 arg1Of sites,NFκB
R1021 T1878 T1875 arg1Of sites,PU.1
R1022 T1878 T1877 arg1Of sites,NFIL-6
R1023 T1882 T1879 arg1Of characterized,","
R1024 T1882 T1880 arg2Of characterized,have
R1025 T1882 T1881 arg2Of characterized,been
R1026 T1882 T1883 arg1Of characterized,previously
R1027 T1882 T1884 arg1Of characterized,[
R1028 T1885 T1884 arg2Of 30-33,[
R1029 T1886 T1884 arg3Of ],[
R1030 T1889 T1887 arg2Of analysis,Using
R1031 T1889 T1888 arg1Of analysis,computational
R1032 T1889 T1890 arg1Of analysis,for
R1033 T1892 T1890 arg2Of search,for
R1034 T1892 T1891 arg1Of search,homology
R1035 T1892 T1893 arg1Of search,[
R1036 T1894 T1893 arg2Of 34,[
R1037 T1895 T1893 arg3Of ],[
R1038 T1897 T1887 arg1Of we,Using
R1039 T1897 T1898 arg1Of we,looked
R1040 T1898 T1887 modOf looked,Using
R1041 T1898 T1896 arg1Of looked,","
R1042 T1898 T1899 arg1Of looked,for
R1043 T1902 T1899 arg2Of motifs,for
R1044 T1902 T1900 arg1Of motifs,new
R1045 T1902 T1901 arg1Of motifs,binding
R1046 T1902 T1903 arg1Of motifs,in
R1047 T1906 T1903 arg2Of promoter,in
R1048 T1906 T1904 arg1Of promoter,the
R1049 T1906 T1905 arg1Of promoter,IL-1RA
R1952 T3337 T3336 arg1Of activities,Binding
R1953 T3337 T3338 arg1Of activities,of
R1954 T3337 T3344 arg1Of activities,from
R1955 T3337 T3347 arg1Of activities,to
R1956 T3339 T3340 arg1Of NFκB,","
R1957 T3340 T3342 arg1Of ",",and
R1958 T3341 T3340 arg2Of NFIL-6,","
R1959 T3342 T3338 arg2Of and,of
R1960 T3343 T3342 arg2Of NFAT,and
R1961 T3346 T3344 arg2Of PBMC,from
R1962 T3346 T3345 arg1Of PBMC,human
R1963 T3349 T3350 arg1Of TNFα,","
R1964 T3350 T3352 arg1Of ",",and
R1965 T3351 T3350 arg2Of IL-6,","
R1966 T3353 T3352 arg2Of IFNγ,and
R1967 T3354 T3347 arg2Of promoters,to
R1968 T3354 T3348 arg1Of promoters,the
R1969 T3354 T3349 arg1Of promoters,TNFα
R1970 T3354 T3351 arg1Of promoters,IL-6
R1971 T3354 T3353 arg1Of promoters,IFNγ
R1972 T3354 T3355 arg1Of promoters,following
R1973 T3358 T3357 arg1Of vitro,in
R1974 T3359 T3355 arg2Of stimulation,following
R1975 T3359 T3356 arg1Of stimulation,an
R1976 T3359 T3358 arg1Of stimulation,vitro
R1977 T3359 T3360 arg1Of stimulation,(
R1978 T3359 T3364 arg1Of stimulation,with
R1979 T3362 T3360 arg2Of h,(
R1980 T3362 T3361 arg1Of h,1
R1981 T3363 T3360 arg3Of ),(
R1982 T3365 T3366 arg1Of LPS,","
R1983 T3366 T3368 arg1Of ",",","
R1984 T3367 T3366 arg2Of TSST-1,","
R1985 T3368 T3370 arg1Of ",",","
R1986 T3369 T3368 arg2Of GP,","
R1987 T3370 T3374 arg1Of ",",and
R1988 T3373 T3370 arg2Of LPS,","
R1989 T3373 T3371 arg1Of LPS,GP
R1990 T3373 T3372 arg1Of LPS,+
R1991 T3374 T3364 arg2Of and,with
R1992 T3377 T3374 arg2Of TSST-1,and
R1993 T3377 T3375 arg1Of TSST-1,GP
R1994 T3377 T3376 arg1Of TSST-1,+
R1995 T3378 T3379 arg1Of GP,induced
R1996 T3379 T3382 arg1Of induced,","
R1997 T3379 T3383 modOf induced,indicating
R1998 T3381 T3379 arg2Of shifts,induced
R1999 T3381 T3380 arg1Of shifts,band
R2000 T3384 T3383 arg2Of binding,indicating
R2001 T3384 T3385 arg1Of binding,of
R2002 T3384 T3390 arg1Of binding,of
R2003 T3385 T3389 arg1Of of,as
R2004 T3386 T3385 arg2Of NFκB,of
R2005 T3389 T3387 arg1Of as,as
R2006 T3389 T3388 arg1Of as,well
R2007 T3390 T3389 arg2Of of,as
R2008 T3391 T3390 arg2Of NFIL-6,of
R2009 T3391 T3392 arg1Of NFIL-6,to
R2010 T3396 T3392 arg2Of oligonucleotides,to
R2011 T3396 T3393 arg1Of oligonucleotides,the
R2012 T3396 T3394 arg1Of oligonucleotides,corresponding
R2013 T3396 T3395 arg1Of oligonucleotides,DNA
R2014 T3396 T3397 arg1Of oligonucleotides,(
R2015 T3399 T3398 arg1Of consensus,κ
R2016 T3399 T3400 arg1Of consensus,","
R2017 T3399 T3402 arg1Of consensus,","
R2018 T3399 T3404 arg1Of consensus,","
R2019 T3401 T3400 arg2Of κ1,","
R2020 T3403 T3402 arg2Of κ2,","
R2021 T3404 T3397 arg2Of ",",(
R2022 T3406 T3404 arg2Of sites,","
R2023 T3406 T3405 arg1Of sites,κ3
R2024 T3406 T3407 arg1Of sites,from
R2025 T3406 T3411 arg1Of sites,;
R2026 T3406 T3418 arg1Of sites,;
R2027 T3406 T3424 arg1Of sites,;
R2028 T3410 T3407 arg2Of promoter,from
R2029 T3410 T3408 arg1Of promoter,the
R2030 T3410 T3409 arg1Of promoter,TNFα
R2031 T3413 T3411 arg2Of consensus,;
R2032 T3413 T3412 arg1Of consensus,κ
R2033 T3413 T3414 arg1Of consensus,from
R2034 T3417 T3414 arg2Of promoter,from
R2035 T3417 T3415 arg1Of promoter,the
R2036 T3417 T3416 arg1Of promoter,IL-8
R2037 T3419 T3418 arg2Of NFIL-6consensus,;
R2038 T3419 T3420 arg1Of NFIL-6consensus,from
R2039 T3423 T3420 arg2Of promoter,from
R2040 T3423 T3421 arg1Of promoter,the
R2041 T3423 T3422 arg1Of promoter,IL-6
R2042 T3425 T3426 arg1Of Table,1
R2043 T3425 T3427 arg1Of Table,;
R2044 T3427 T3424 arg2Of ;,;
R2045 T3429 T3427 arg2Of 1A,;
R2046 T3429 T3428 arg1Of 1A,Fig.
R2047 T3430 T3397 arg3Of ),(
R2048 T3432 T3431 arg1Of extent,The
R2049 T3432 T3433 arg1Of extent,of
R2050 T3432 T3440 arg1Of extent,was
R2051 T3432 T3443 arg1Of extent,different
R2052 T3432 T3445 arg1Of extent,compared
R2053 T3436 T3433 arg2Of shifts,of
R2054 T3436 T3434 arg1Of shifts,the
R2055 T3436 T3435 arg1Of shifts,band
R2056 T3436 T3437 arg2Of shifts,induced
R2057 T3439 T3437 arg1Of GP,induced
R2058 T3439 T3438 arg2Of GP,by
R2059 T3440 T3441 arg1Of was,not
R2060 T3440 T3444 arg1Of was,when
R2061 T3443 T3440 arg2Of different,was
R2062 T3443 T3442 arg1Of different,statistically
R2063 T3445 T3444 arg2Of compared,when
R2064 T3445 T3446 arg1Of compared,to
R2065 T3447 T3448 arg1Of LPS,or
R2066 T3448 T3446 arg2Of or,to
R2067 T3448 T3450 arg1Of or,(
R2068 T3449 T3448 arg2Of TSST-1,or
R2069 T3452 T3450 arg2Of 1B,(
R2070 T3452 T3451 arg1Of 1B,Fig.
R2071 T3453 T3450 arg3Of ),(
R2072 T3455 T3454 arg1Of supershift,A
R2073 T3455 T3456 arg1Of supershift,","
R2074 T3455 T3457 arg2Of supershift,conducted
R2075 T3455 T3468 arg1Of supershift,demonstrated
R2076 T3457 T3458 arg1Of conducted,for
R2077 T3462 T3458 arg2Of site,for
R2078 T3462 T3459 arg1Of site,an
R2079 T3462 T3460 arg1Of site,NFκB
R2080 T3462 T3461 arg1Of site,consensus
R2081 T3462 T3463 arg1Of site,from
R2082 T3466 T3463 arg2Of promoter,from
R2083 T3466 T3464 arg1Of promoter,the
R2084 T3466 T3465 arg1Of promoter,IL-8
R2085 T3468 T3467 arg1Of demonstrated,","
R2086 T3472 T3468 arg2Of binding,demonstrated
R2087 T3472 T3469 arg1Of binding,a
R2088 T3472 T3470 arg1Of binding,GP-induced
R2089 T3472 T3471 arg1Of binding,predominant
R2090 T3472 T3473 arg1Of binding,of
R2091 T3472 T3477 arg1Of binding,to
R2092 T3473 T3476 arg1Of of,and
R2093 T3475 T3473 arg2Of p65,of
R2094 T3475 T3474 arg1Of p65,NFκB
R2095 T3477 T3476 arg2Of to,and
R2096 T3480 T3477 arg2Of degree,to
R2097 T3480 T3478 arg1Of degree,a
R2098 T3480 T3479 arg1Of degree,lesser
R2099 T3480 T3481 arg1Of degree,of
R2100 T3482 T3481 arg2Of p50,of
R2101 T3482 T3483 arg1Of p50,(
R2102 T3485 T3483 arg2Of 1A,(
R2103 T3485 T3484 arg1Of 1A,Fig.
R2104 T3486 T3483 arg3Of ),(
R2105 T3490 T3489 arg1Of immunoblot,an
R2106 T3490 T3491 arg1Of immunoblot,of
R2107 T3490 T3497 arg1Of immunoblot,showed
R2108 T3493 T3491 arg2Of extracts,of
R2109 T3493 T3492 arg1Of extracts,nuclear
R2110 T3493 T3494 arg1Of extracts,from
R2111 T3496 T3494 arg2Of PBMC,from
R2112 T3496 T3495 arg1Of PBMC,GP-treated
R2113 T3497 T3511 arg1Of showed,whereas
R2114 T3500 T3498 arg1Of binding,a
R2115 T3500 T3499 arg1Of binding,strong
R2116 T3500 T3501 arg1Of binding,of
R2117 T3500 T3504 arg1Of binding,and
R2118 T3503 T3501 arg2Of p65,of
R2119 T3503 T3502 arg1Of p65,NFκB
R2120 T3504 T3497 arg2Of and,showed
R2121 T3507 T3504 arg2Of reaction,and
R2122 T3507 T3505 arg1Of reaction,a
R2123 T3507 T3506 arg1Of reaction,weaker
R2124 T3507 T3508 arg1Of reaction,of
R2125 T3509 T3508 arg2Of p50,of
R2126 T3511 T3487 arg1Of whereas,Accordingly
R2127 T3511 T3488 arg1Of whereas,","
R2128 T3511 T3510 arg1Of whereas,","
R2129 T3512 T3513 arg1Of p52,was
R2130 T3512 T3514 arg1Of p52,negative
R2131 T3513 T3511 arg2Of was,whereas
R2132 T3514 T3513 arg2Of negative,was
R2133 T3514 T3515 arg1Of negative,(
R2134 T3516 T3515 arg2Of Fig.,(
R2135 T3516 T3517 arg1Of Fig.,2
R2136 T3518 T3515 arg3Of ),(
R2137 T3520 T3519 arg1Of co-treatment,Simultaneous
R2138 T3520 T3521 arg1Of co-treatment,of
R2139 T3520 T3523 arg1Of co-treatment,with
R2140 T3520 T3525 arg1Of co-treatment,did
R2141 T3520 T3527 arg1Of co-treatment,change
R2142 T3520 T3546 arg1Of co-treatment,decreased
R2143 T3520 T3552 arg1Of co-treatment,compared
R2144 T3520 T3563 arg1Of co-treatment,differed
R2145 T3522 T3521 arg2Of PBMC,of
R2146 T3524 T3523 arg2Of GP,with
R2147 T3527 T3525 arg2Of change,did
R2148 T3527 T3526 arg1Of change,not
R2149 T3527 T3544 arg1Of change,but
R2150 T3530 T3527 arg2Of NFκB,change
R2151 T3530 T3528 arg1Of NFκB,the
R2152 T3530 T3529 arg1Of NFκB,LPS-induced
R2153 T3530 T3531 arg1Of NFκB,binding
R2154 T3531 T3532 arg1Of binding,to
R2155 T3531 T3538 arg1Of binding,significantly
R2156 T3531 T3539 arg1Of binding,(
R2157 T3533 T3532 arg2Of oligos,to
R2158 T3533 T3534 arg1Of oligos,from
R2159 T3537 T3534 arg2Of promoter,from
R2160 T3537 T3535 arg1Of promoter,the
R2161 T3537 T3536 arg1Of promoter,TNFα
R2162 T3541 T3539 arg2Of 1B,(
R2163 T3541 T3540 arg1Of 1B,Fig.
R2164 T3542 T3539 arg3Of ),(
R2165 T3544 T3543 arg1Of but,","
R2166 T3546 T3551 arg1Of decreased,when
R2167 T3546 T3561 arg1Of decreased,and
R2168 T3550 T3546 arg2Of binding,decreased
R2169 T3550 T3547 arg1Of binding,the
R2170 T3550 T3548 arg1Of binding,TSST-1-induced
R2171 T3550 T3549 arg1Of binding,NFκB
R2172 T3552 T3551 arg2Of compared,when
R2173 T3552 T3553 arg1Of compared,to
R2174 T3554 T3555 arg1Of TSST-1,or
R2175 T3555 T3553 arg2Of or,to
R2176 T3555 T3557 arg1Of or,(
R2177 T3556 T3555 arg2Of GP,or
R2178 T3559 T3557 arg2Of μg,(
R2179 T3559 T3558 arg1Of μg,100
R2180 T3560 T3557 arg3Of ),(
R2181 T3561 T3544 arg2Of and,but
R2182 T3561 T3545 arg1Of and,substantially
R2183 T3563 T3561 arg2Of differed,and
R2184 T3563 T3562 arg1Of differed,thus
R2185 T3563 T3564 arg1Of differed,completely
R2186 T3563 T3565 arg1Of differed,from
R2187 T3568 T3565 arg2Of value,from
R2188 T3568 T3566 arg1Of value,the
R2189 T3568 T3567 arg1Of value,theoretical
R2190 T3568 T3569 arg1Of value,of
R2191 T3568 T3572 arg1Of value,(
R2192 T3571 T3569 arg2Of calc.,of
R2193 T3571 T3570 arg1Of calc.,GP/TSST-1
R2194 T3573 T3572 arg2Of n,(
R2195 T3573 T3574 arg1Of n,=
R2196 T3573 T3576 arg1Of n,;
R2197 T3573 T3589 arg1Of n,;
R2198 T3574 T3575 arg1Of =,4
R2199 T3577 T3578 arg1Of p,<
R2200 T3579 T3580 arg1Of 0.05,vs.
R2201 T3582 T3581 arg1Of calc.,GP/TSST-1
R2202 T3582 T3583 arg1Of calc.,and
R2203 T3583 T3580 arg2Of and,vs.
R2204 T3584 T3583 arg2Of p,and
R2205 T3584 T3585 arg1Of p,=
R2206 T3586 T3576 arg2Of 0.07,;
R2207 T3586 T3577 arg1Of 0.07,p
R2208 T3586 T3579 arg1Of 0.07,0.05
R2209 T3586 T3587 arg1Of 0.07,vs.
R2210 T3588 T3587 arg2Of TSST-1,vs.
R2211 T3591 T3589 arg2Of 1B,;
R2212 T3591 T3590 arg1Of 1B,Fig.
R2213 T3592 T3572 arg3Of ),(
R2214 T3593 T3594 arg1Of GP,was
R2215 T3593 T3596 arg1Of GP,able
R2216 T3593 T3598 arg1Of GP,induce
R2217 T3594 T3595 arg1Of was,also
R2218 T3596 T3594 arg2Of able,was
R2219 T3598 T3596 arg2Of induce,able
R2220 T3598 T3597 arg1Of induce,to
R2221 T3600 T3598 arg2Of shifts,induce
R2222 T3600 T3599 arg1Of shifts,band
R2223 T3600 T3601 arg1Of shifts,indicative
R2224 T3601 T3602 arg1Of indicative,of
R2225 T3603 T3602 arg2Of binding,of
R2226 T3603 T3604 arg1Of binding,of
R2227 T3603 T3609 arg1Of binding,to
R2228 T3606 T3604 arg2Of variants,of
R2229 T3606 T3605 arg1Of variants,particular
R2230 T3606 T3607 arg1Of variants,of
R2231 T3608 T3607 arg2Of NFAT,of
R2232 T3611 T3609 arg2Of oligo,to
R2233 T3611 T3610 arg1Of oligo,an
R2234 T3611 T3612 arg1Of oligo,from
R2235 T3615 T3612 arg2Of promoter,from
R2236 T3615 T3613 arg1Of promoter,the
R2237 T3615 T3614 arg1Of promoter,IFNγ
R2238 T3615 T3616 arg1Of promoter,(
R2239 T3618 T3616 arg2Of 1A,(
R2240 T3618 T3617 arg1Of 1A,Fig.
R2241 T3619 T3616 arg3Of ),(
R2242 T3621 T3620 arg1Of immunoblot,An
R2243 T3621 T3622 arg1Of immunoblot,for
R2244 T3621 T3626 arg1Of immunoblot,demonstrated
R2245 T3625 T3622 arg2Of subunits,for
R2246 T3625 T3623 arg1Of subunits,two
R2247 T3625 T3624 arg1Of subunits,NFAT
R2248 T3626 T3632 arg1Of demonstrated,and
R2249 T3626 T3633 arg1Of demonstrated,to
R2250 T3629 T3626 arg2Of binding,demonstrated
R2251 T3629 T3627 arg1Of binding,a
R2252 T3629 T3628 arg1Of binding,GP-induced
R2253 T3629 T3630 arg1Of binding,of
R2254 T3631 T3630 arg2Of NFATc2,of
R2255 T3636 T3633 arg2Of degree,to
R2256 T3636 T3634 arg1Of degree,a
R2257 T3636 T3635 arg1Of degree,lesser
R2258 T3636 T3637 arg1Of degree,of
R2259 T3638 T3637 arg2Of NFATc1,of
R2260 T3638 T3639 arg1Of NFATc1,(
R2261 T3640 T3639 arg2Of Fig.,(
R2262 T3640 T3641 arg1Of Fig.,2
R2263 T3642 T3639 arg3Of ),(
R2955 T5174 T5173 arg1Of profile,Cytokine
R2956 T5174 T5175 arg1Of profile,of
R2957 T5174 T5178 arg1Of profile,following
R2958 T5177 T5175 arg2Of PBMC,of
R2959 T5177 T5176 arg1Of PBMC,human
R2960 T5183 T5182 arg1Of vitro,in
R2961 T5184 T5178 arg2Of stimulation,following
R2962 T5184 T5179 arg1Of stimulation,a
R2963 T5184 T5180 arg1Of stimulation,48
R2964 T5184 T5181 arg1Of stimulation,h
R2965 T5184 T5183 arg1Of stimulation,vitro
R2966 T5184 T5185 arg1Of stimulation,with
R2967 T5186 T5187 arg1Of LPS,","
R2968 T5187 T5189 arg1Of ",",","
R2969 T5188 T5187 arg2Of TSST-1,","
R2970 T5189 T5191 arg1Of ",",","
R2971 T5190 T5189 arg2Of GP,","
R2972 T5191 T5195 arg1Of ",",and
R2973 T5194 T5191 arg2Of LPS,","
R2974 T5194 T5192 arg1Of LPS,GP
R2975 T5194 T5193 arg1Of LPS,+
R2976 T5195 T5185 arg2Of and,with
R2977 T5198 T5195 arg2Of TSST-1,and
R2978 T5198 T5196 arg1Of TSST-1,GP
R2979 T5198 T5197 arg1Of TSST-1,+
R2980 T5199 T5200 arg1Of Because,of
R2981 T5204 T5199 arg2Of shifts,Because
R2982 T5204 T5201 arg1Of shifts,the
R2983 T5204 T5202 arg1Of shifts,GP-induced
R2984 T5204 T5203 arg1Of shifts,band
R2985 T5204 T5205 arg1Of shifts,to
R2986 T5207 T5205 arg2Of sites,to
R2987 T5207 T5206 arg1Of sites,seven
R2988 T5207 T5208 arg1Of sites,from
R2989 T5210 T5211 arg1Of TNFα,","
R2990 T5211 T5213 arg1Of ",",","
R2991 T5212 T5211 arg2Of IL-8,","
R2992 T5213 T5215 arg1Of ",",and
R2993 T5214 T5213 arg2Of IL-6,","
R2994 T5216 T5215 arg2Of IFNγ,and
R2995 T5217 T5208 arg2Of promoters,from
R2996 T5217 T5209 arg1Of promoters,the
R2997 T5217 T5210 arg1Of promoters,TNFα
R2998 T5217 T5212 arg1Of promoters,IL-8
R2999 T5217 T5214 arg1Of promoters,IL-6
R3000 T5217 T5216 arg1Of promoters,IFNγ
R3001 T5219 T5220 arg1Of it,could
R3002 T5219 T5221 arg1Of it,be
R3003 T5219 T5222 arg2Of it,assumed
R3004 T5222 T5199 arg1Of assumed,Because
R3005 T5222 T5218 arg1Of assumed,","
R3006 T5222 T5220 arg2Of assumed,could
R3007 T5222 T5221 arg2Of assumed,be
R3008 T5225 T5224 arg1Of treatment,GP
R3009 T5225 T5226 arg1Of treatment,of
R3010 T5225 T5229 arg1Of treatment,would
R3011 T5225 T5230 arg1Of treatment,lead
R3012 T5228 T5226 arg2Of PBMC,of
R3013 T5228 T5227 arg1Of PBMC,human
R3014 T5230 T5222 arg3Of lead,assumed
R3015 T5230 T5223 arg1Of lead,that
R3016 T5230 T5229 arg2Of lead,would
R3017 T5230 T5231 arg1Of lead,to
R3018 T5232 T5231 arg2Of production,to
R3019 T5232 T5233 arg1Of production,of
R3020 T5234 T5235 arg1Of TNFα,","
R3021 T5235 T5237 arg1Of ",",","
R3022 T5236 T5235 arg2Of IL-8,","
R3023 T5237 T5239 arg1Of ",",","
R3024 T5238 T5237 arg2Of IL-6,","
R3025 T5239 T5241 arg1Of ",",and
R3026 T5240 T5239 arg2Of IFNγ,","
R3027 T5241 T5233 arg2Of and,of
R3028 T5244 T5241 arg2Of mediators,and
R3029 T5244 T5242 arg1Of mediators,other
R3030 T5244 T5243 arg1Of mediators,pro-inflammatory
R3031 T5246 T5245 arg1Of studies,Previous
R3032 T5246 T5247 arg1Of studies,reported
R3033 T5249 T5250 arg1Of β-1→3-D-glucans,induced
R3034 T5250 T5247 arg2Of induced,reported
R3035 T5250 T5248 arg1Of induced,that
R3036 T5255 T5250 arg2Of secretion,induced
R3037 T5255 T5251 arg1Of secretion,only
R3038 T5255 T5252 arg1Of secretion,a
R3039 T5255 T5253 arg1Of secretion,limited
R3040 T5255 T5254 arg1Of secretion,cytokine
R3041 T5255 T5256 arg1Of secretion,of
R3042 T5255 T5260 arg1Of secretion,[
R3043 T5259 T5256 arg2Of cells,of
R3044 T5259 T5257 arg1Of cells,human
R3045 T5259 T5258 arg1Of cells,blood
R3046 T5261 T5260 arg2Of 15-18,[
R3047 T5262 T5260 arg3Of ],[
R3048 T5263 T5264 arg1Of Corroborating,and
R3049 T5265 T5264 arg2Of extending,and
R3050 T5268 T5263 arg2Of findings,Corroborating
R3051 T5268 T5265 arg2Of findings,extending
R3052 T5268 T5266 arg1Of findings,these
R3053 T5268 T5267 arg1Of findings,singular
R3054 T5268 T5269 arg1Of findings,in
R3055 T5270 T5269 arg2Of terms,in
R3056 T5270 T5271 arg1Of terms,of
R3057 T5272 T5271 arg2Of examining,of
R3058 T5272 T5286 arg1Of examining,over
R3059 T5273 T5274 arg1Of pro-,(
R3060 T5273 T5279 arg1Of pro-,as
R3061 T5275 T5274 arg2Of eight,(
R3062 T5276 T5274 arg3Of ),(
R3063 T5279 T5272 arg2Of as,examining
R3064 T5279 T5277 arg1Of as,as
R3065 T5279 T5278 arg1Of as,well
R3066 T5280 T5281 arg1Of anti-,(
R3067 T5282 T5281 arg2Of three,(
R3068 T5283 T5281 arg3Of ),(
R3069 T5285 T5279 arg2Of cytokines,as
R3070 T5285 T5280 arg1Of cytokines,anti-
R3071 T5285 T5284 arg1Of cytokines,inflammatory
R3072 T5287 T5288 arg1Of time,(
R3073 T5287 T5292 arg1Of time,and
R3074 T5290 T5288 arg2Of h,(
R3075 T5290 T5289 arg1Of h,48
R3076 T5291 T5288 arg3Of ),(
R3077 T5292 T5286 arg2Of and,over
R3078 T5298 T5292 arg2Of sites,and
R3079 T5298 T5293 arg1Of sites,six
R3080 T5298 T5294 arg1Of sites,additional
R3081 T5298 T5295 arg1Of sites,transcription
R3082 T5298 T5296 arg1Of sites,factor
R3083 T5298 T5297 arg1Of sites,binding
R3084 T5302 T5265 arg1Of analysis,extending
R3085 T5302 T5300 arg1Of analysis,our
R3086 T5302 T5301 arg1Of analysis,comprehensive
R3087 T5302 T5303 arg1Of analysis,revealed
R3088 T5303 T5263 modOf revealed,Corroborating
R3089 T5303 T5265 modOf revealed,extending
R3090 T5303 T5299 arg1Of revealed,","
R3091 T5303 T5311 arg1Of revealed,in
R3092 T5303 T5321 arg1Of revealed,in
R3093 T5307 T5303 arg2Of profile,revealed
R3094 T5307 T5304 arg1Of profile,the
R3095 T5307 T5305 arg1Of profile,following
R3096 T5307 T5306 arg1Of profile,cytokine
R3097 T5307 T5308 arg1Of profile,of
R3098 T5310 T5308 arg2Of leukocytes,of
R3099 T5310 T5309 arg1Of leukocytes,human
R3100 T5311 T5313 arg1Of in,to
R3101 T5311 T5320 arg1Of in,and
R3102 T5312 T5311 arg2Of response,in
R3103 T5316 T5315 arg1Of purified,highly
R3104 T5319 T5311 arg3Of β-1→3-D-glucan,in
R3105 T5319 T5314 arg1Of β-1→3-D-glucan,a
R3106 T5319 T5316 arg1Of β-1→3-D-glucan,purified
R3107 T5319 T5317 arg1Of β-1→3-D-glucan,water
R3108 T5319 T5318 arg1Of β-1→3-D-glucan,soluble
R3109 T5321 T5320 arg2Of in,and
R3110 T5322 T5321 arg2Of comparison,in
R3111 T5322 T5323 arg1Of comparison,to
R3112 T5326 T5323 arg2Of mediators,to
R3113 T5326 T5324 arg1Of mediators,two
R3114 T5326 T5325 arg1Of mediators,pro-inflammatory
R3115 T5326 T5327 arg1Of mediators,(
R3116 T5326 T5332 arg1Of mediators,:
R3117 T5328 T5327 arg2Of LPS,(
R3118 T5328 T5329 arg1Of LPS,","
R3119 T5330 T5329 arg2Of TSST-1,","
R3120 T5331 T5327 arg3Of ),(
R3121 T5334 T5335 arg1Of i,)
R3122 T5336 T5333 arg1Of IL-1β,(
R3123 T5336 T5334 arg1Of IL-1β,i
R3124 T5337 T5338 arg1Of There,was
R3125 T5341 T5338 arg2Of production,was
R3126 T5341 T5339 arg1Of production,no
R3127 T5341 T5340 arg1Of production,IL-1β
R3128 T5341 T5342 arg1Of production,detectable
R3129 T5342 T5343 arg1Of detectable,following
R3130 T5345 T5343 arg2Of treatment,following
R3131 T5345 T5344 arg1Of treatment,PBMC
R3132 T5345 T5346 arg1Of treatment,with
R3133 T5347 T5348 arg1Of 1,nor
R3134 T5349 T5348 arg2Of 100,nor
R3135 T5351 T5346 arg2Of GP,with
R3136 T5351 T5347 arg1Of GP,1
R3137 T5351 T5349 arg1Of GP,100
R3138 T5351 T5350 arg1Of GP,μg
R3139 T5354 T5352 arg1Of up-regulation,An
R3140 T5354 T5353 arg1Of up-regulation,insignificant
R3141 T5354 T5355 arg1Of up-regulation,of
R3142 T5354 T5362 arg1Of up-regulation,was
R3143 T5354 T5363 arg2Of up-regulation,observed
R3144 T5357 T5355 arg2Of production,of
R3145 T5357 T5356 arg1Of production,IL-1β
R3146 T5357 T5358 arg1Of production,for
R3147 T5361 T5358 arg2Of LPS,for
R3148 T5361 T5359 arg1Of LPS,GP
R3149 T5361 T5360 arg1Of LPS,+
R3150 T5363 T5362 arg2Of observed,was
R3151 T5363 T5364 arg1Of observed,in
R3152 T5365 T5364 arg2Of comparison,in
R3153 T5365 T5366 arg1Of comparison,with
R3154 T5367 T5366 arg2Of LPS,with
R3155 T5369 T5368 arg2Of GP,For
R3156 T5369 T5370 arg1Of GP,+
R3157 T5372 T5373 arg1Of we,found
R3158 T5372 T5394 arg1Of we,compared
R3159 T5373 T5368 arg1Of found,For
R3160 T5373 T5371 arg1Of found,TSST-1
R3161 T5373 T5382 arg1Of found,–
R3162 T5373 T5385 arg1Of found,","
R3163 T5373 T5386 arg1Of found,for
R3164 T5373 T5389 arg1Of found,by
R3165 T5373 T5393 arg1Of found,when
R3166 T5373 T5404 arg1Of found,(
R3167 T5376 T5373 arg2Of reduction,found
R3168 T5376 T5374 arg1Of reduction,a
R3169 T5376 T5375 arg1Of reduction,significant
R3170 T5376 T5377 arg1Of reduction,in
R3171 T5378 T5377 arg2Of IL-1β,in
R3172 T5378 T5379 arg1Of IL-1β,from
R3173 T5381 T5379 arg2Of h,from
R3174 T5381 T5380 arg1Of h,18
R3175 T5384 T5382 arg2Of h,–
R3176 T5384 T5383 arg1Of h,24
R3177 T5388 T5386 arg2Of latter,for
R3178 T5388 T5387 arg1Of latter,the
R3179 T5392 T5389 arg2Of %,by
R3180 T5392 T5390 arg1Of %,about
R3181 T5392 T5391 arg1Of %,40
R3182 T5394 T5393 arg2Of compared,when
R3183 T5394 T5395 arg1Of compared,to
R3184 T5396 T5397 arg1Of TSST-1,or
R3185 T5397 T5395 arg2Of or,to
R3186 T5400 T5397 arg2Of value,or
R3187 T5400 T5398 arg1Of value,the
R3188 T5400 T5399 arg1Of value,theoretical
R3189 T5400 T5401 arg1Of value,of
R3190 T5403 T5401 arg2Of calc.,of
R3191 T5403 T5402 arg1Of calc.,GP/TSST-1
R3192 T5405 T5404 arg2Of n,(
R3193 T5405 T5406 arg1Of n,=
R3194 T5405 T5408 arg1Of n,;
R3195 T5406 T5407 arg1Of =,6
R3196 T5410 T5408 arg2Of p,;
R3197 T5410 T5409 arg1Of p,both
R3198 T5410 T5411 arg1Of p,=
R3199 T5410 T5412 arg1Of p,0.01
R3200 T5413 T5404 arg3Of ),(
R3201 T5416 T5414 arg2Of whole,On
R3202 T5416 T5415 arg1Of whole,the
R3203 T5418 T5419 arg1Of GP,mediated
R3204 T5419 T5414 arg1Of mediated,On
R3205 T5419 T5417 arg1Of mediated,","
R3206 T5421 T5419 arg2Of reduction,mediated
R3207 T5421 T5420 arg1Of reduction,a
R3208 T5421 T5422 arg1Of reduction,of
R3209 T5421 T5428 arg1Of reduction,by
R3210 T5425 T5422 arg2Of amount,of
R3211 T5425 T5423 arg1Of amount,the
R3212 T5425 T5424 arg1Of amount,TSST-1-induced
R3213 T5425 T5426 arg1Of amount,of
R3214 T5427 T5426 arg2Of IL-1β,of
R3215 T5430 T5429 arg1Of 50,about
R3216 T5431 T5428 arg2Of %,by
R3217 T5431 T5430 arg1Of %,50
R3218 T5431 T5432 arg1Of %,(
R3219 T5434 T5432 arg2Of 3A,(
R3220 T5434 T5433 arg1Of 3A,Fig.
R3221 T5435 T5432 arg3Of ),(
R3222 T5437 T5438 arg1Of ii,)
R3223 T5439 T5436 arg1Of IL-6,(
R3224 T5439 T5437 arg1Of IL-6,ii
R3225 T5440 T5441 arg1Of GP,induced
R3226 T5441 T5448 arg1Of induced,and
R3227 T5445 T5441 arg2Of amount,induced
R3228 T5445 T5442 arg1Of amount,only
R3229 T5445 T5443 arg1Of amount,a
R3230 T5445 T5444 arg1Of amount,small
R3231 T5445 T5446 arg1Of amount,of
R3232 T5447 T5446 arg2Of IL-6,of
R3233 T5449 T5450 arg1Of there,was
R3234 T5450 T5448 arg2Of was,and
R3235 T5453 T5450 arg2Of alteration,was
R3236 T5453 T5451 arg1Of alteration,no
R3237 T5453 T5452 arg1Of alteration,significant
R3238 T5453 T5454 arg1Of alteration,of
R3239 T5453 T5459 arg1Of alteration,by
R3240 T5458 T5454 arg2Of production,of
R3241 T5458 T5455 arg1Of production,the
R3242 T5458 T5456 arg1Of production,LPS-induced
R3243 T5458 T5457 arg1Of production,IL-6
R3244 T5460 T5459 arg2Of GP,by
R3245 T5463 T5461 arg2Of contrary,On
R3246 T5463 T5462 arg1Of contrary,the
R3247 T5465 T5466 arg1Of we,observed
R3248 T5465 T5476 arg1Of we,compared
R3249 T5466 T5461 arg1Of observed,On
R3250 T5466 T5464 arg1Of observed,","
R3251 T5466 T5475 arg1Of observed,when
R3252 T5466 T5482 arg1Of observed,","
R3253 T5466 T5484 arg1Of observed,at
R3254 T5470 T5466 arg2Of production,observed
R3255 T5470 T5467 arg1Of production,a
R3256 T5470 T5468 arg2Of production,decreased
R3257 T5470 T5469 arg1Of production,IL-6
R3258 T5470 T5471 arg1Of production,for
R3259 T5474 T5471 arg2Of TSST-1,for
R3260 T5474 T5472 arg1Of TSST-1,GP
R3261 T5474 T5473 arg1Of TSST-1,+
R3262 T5476 T5475 arg2Of compared,when
R3263 T5476 T5477 arg1Of compared,to
R3264 T5478 T5479 arg1Of TSST-1,or
R3265 T5480 T5479 arg2Of GP/TSST-1,or
R3266 T5481 T5477 arg2Of calc.,to
R3267 T5481 T5478 arg1Of calc.,TSST-1
R3268 T5481 T5480 arg1Of calc.,GP/TSST-1
R3269 T5484 T5483 arg1Of at,especially
R3270 T5486 T5484 arg2Of h,at
R3271 T5486 T5485 arg1Of h,24
R3272 T5486 T5487 arg1Of h,by
R3273 T5486 T5501 arg1Of h,","
R3274 T5486 T5502 arg1Of h,(
R3275 T5489 T5488 arg1Of 40,about
R3276 T5490 T5487 arg2Of %,by
R3277 T5490 T5489 arg1Of %,40
R3278 T5490 T5491 arg1Of %,(
R3279 T5496 T5495 arg1Of both,;
R3280 T5497 T5491 arg2Of p,(
R3281 T5497 T5492 arg1Of p,n
R3282 T5497 T5493 arg1Of p,=
R3283 T5497 T5494 arg1Of p,5
R3284 T5497 T5496 arg1Of p,both
R3285 T5497 T5498 arg1Of p,=
R3286 T5497 T5499 arg1Of p,0.02
R3287 T5500 T5491 arg3Of ),(
R3288 T5503 T5502 arg2Of data,(
R3289 T5503 T5505 arg2Of data,shown
R3290 T5505 T5504 arg1Of shown,not
R3291 T5505 T5506 arg1Of shown,in
R3292 T5507 T5506 arg2Of detail,in
R3293 T5508 T5502 arg3Of ),(
R3294 T5510 T5511 arg1Of iii,)
R3295 T5512 T5509 arg1Of IL-8,(
R3296 T5512 T5510 arg1Of IL-8,iii
R3297 T5513 T5514 arg1Of We,found
R3298 T5516 T5517 arg1Of GP,induced
R3299 T5517 T5514 arg2Of induced,found
R3300 T5517 T5515 arg1Of induced,that
R3301 T5517 T5522 arg1Of induced,","
R3302 T5517 T5523 arg1Of induced,in
R3303 T5517 T5528 arg1Of induced,","
R3304 T5517 T5530 arg1Of induced,at
R3305 T5521 T5517 arg2Of production,induced
R3306 T5521 T5518 arg1Of production,a
R3307 T5521 T5519 arg1Of production,substantial
R3308 T5521 T5520 arg1Of production,IL-8
R3309 T5524 T5523 arg2Of comparison,in
R3310 T5524 T5525 arg1Of comparison,with
R3311 T5527 T5525 arg2Of control,with
R3312 T5527 T5526 arg1Of control,medium
R3313 T5530 T5529 arg1Of at,especially
R3314 T5532 T5530 arg2Of h,at
R3315 T5532 T5531 arg1Of h,24
R3316 T5532 T5533 arg1Of h,(
R3317 T5534 T5533 arg2Of n,(
R3318 T5534 T5535 arg1Of n,=
R3319 T5534 T5537 arg1Of n,;
R3320 T5535 T5536 arg1Of =,13
R3321 T5538 T5537 arg2Of p,;
R3322 T5538 T5539 arg1Of p,<
R3323 T5538 T5540 arg1Of p,0.01
R3324 T5541 T5533 arg3Of ),(
R3325 T5543 T5542 arg1Of combination,A
R3326 T5543 T5544 arg1Of combination,of
R3327 T5543 T5548 arg1Of combination,resulted
R3328 T5543 T5557 arg1Of combination,compared
R3329 T5545 T5546 arg1Of GP,and
R3330 T5546 T5544 arg2Of and,of
R3331 T5547 T5546 arg2Of LPS,and
R3332 T5548 T5549 arg1Of resulted,in
R3333 T5548 T5556 arg1Of resulted,when
R3334 T5552 T5549 arg2Of increase,in
R3335 T5552 T5550 arg1Of increase,a
R3336 T5552 T5551 arg1Of increase,non-significant
R3337 T5552 T5553 arg1Of increase,of
R3338 T5555 T5553 arg2Of production,of
R3339 T5555 T5554 arg1Of production,IL-8
R3340 T5557 T5556 arg2Of compared,when
R3341 T5557 T5558 arg1Of compared,to
R3342 T5559 T5560 arg1Of LPS,or
R3343 T5560 T5558 arg2Of or,to
R3344 T5562 T5560 arg2Of calc,or
R3345 T5562 T5561 arg1Of calc,GP/LPS
R3346 T5563 T5564 arg1Of There,was
R3347 T5563 T5576 arg1Of There,compared
R3348 T5564 T5568 arg1Of was,in
R3349 T5564 T5575 arg1Of was,when
R3350 T5567 T5564 arg2Of alteration,was
R3351 T5567 T5565 arg1Of alteration,no
R3352 T5567 T5566 arg1Of alteration,significant
R3353 T5570 T5568 arg2Of production,in
R3354 T5570 T5569 arg1Of production,IL-8
R3355 T5570 T5571 arg1Of production,following
R3356 T5574 T5571 arg2Of TSST-1,following
R3357 T5574 T5572 arg1Of TSST-1,GP
R3358 T5574 T5573 arg1Of TSST-1,+
R3359 T5576 T5575 arg2Of compared,when
R3360 T5576 T5577 arg1Of compared,to
R3361 T5578 T5579 arg1Of TSST-1,or
R3362 T5579 T5577 arg2Of or,to
R3363 T5581 T5579 arg2Of calc.,or
R3364 T5581 T5580 arg1Of calc.,GP/TSST-1
R3365 T5581 T5582 arg1Of calc.,(
R3366 T5583 T5582 arg2Of data,(
R3367 T5583 T5585 arg2Of data,shown
R3368 T5585 T5584 arg1Of shown,not
R3369 T5585 T5586 arg1Of shown,in
R3370 T5587 T5586 arg2Of detail,in
R3371 T5588 T5582 arg3Of ),(
R3372 T5590 T5591 arg1Of iv,)
R3373 T5592 T5589 arg1Of IL-1RA,(
R3374 T5592 T5590 arg1Of IL-1RA,iv
R3375 T5594 T5593 arg2Of IL-8,Besides
R3376 T5596 T5597 arg1Of IL-1RA,was
R3377 T5597 T5593 arg1Of was,Besides
R3378 T5597 T5595 arg1Of was,","
R3379 T5600 T5597 arg2Of mediator,was
R3380 T5600 T5598 arg1Of mediator,the
R3381 T5600 T5599 arg1Of mediator,only
R3382 T5600 T5601 arg1Of mediator,which
R3383 T5600 T5602 arg1Of mediator,was
R3384 T5600 T5603 arg2Of mediator,produced
R3385 T5603 T5602 arg2Of produced,was
R3386 T5603 T5604 arg1Of produced,in
R3387 T5603 T5607 arg1Of produced,following
R3388 T5603 T5610 arg1Of produced,","
R3389 T5603 T5612 arg1Of produced,at
R3390 T5606 T5604 arg2Of quantities,in
R3391 T5606 T5605 arg1Of quantities,significant
R3392 T5609 T5607 arg2Of treatment,following
R3393 T5609 T5608 arg1Of treatment,GP
R3394 T5612 T5611 arg1Of at,especially
R3395 T5614 T5612 arg2Of h,at
R3396 T5614 T5613 arg1Of h,24
R3397 T5614 T5615 arg1Of h,(
R3398 T5616 T5615 arg2Of n,(
R3399 T5616 T5617 arg1Of n,=
R3400 T5616 T5619 arg1Of n,","
R3401 T5617 T5618 arg1Of =,14
R3402 T5620 T5619 arg2Of p,","
R3403 T5620 T5621 arg1Of p,<
R3404 T5620 T5622 arg1Of p,0.01
R3405 T5623 T5615 arg3Of ),(
R3406 T5625 T5624 arg2Of compared,When
R3407 T5625 T5626 arg1Of compared,to
R3408 T5628 T5627 arg1Of stimulation,LPS
R3409 T5628 T5629 arg1Of stimulation,or
R3410 T5629 T5626 arg2Of or,to
R3411 T5631 T5629 arg2Of calc.,or
R3412 T5631 T5630 arg1Of calc.,GP/LPS
R3413 T5635 T5633 arg1Of LPS,GP
R3414 T5635 T5634 arg1Of LPS,+
R3415 T5635 T5636 arg1Of LPS,did
R3416 T5635 T5638 arg1Of LPS,alter
R3417 T5638 T5624 arg1Of alter,When
R3418 T5638 T5632 arg1Of alter,","
R3419 T5638 T5636 arg2Of alter,did
R3420 T5638 T5637 arg1Of alter,not
R3421 T5641 T5638 arg2Of course,alter
R3422 T5641 T5639 arg1Of course,the
R3423 T5641 T5640 arg1Of course,kinetic
R3424 T5641 T5642 arg1Of course,of
R3425 T5645 T5642 arg2Of production,of
R3426 T5645 T5643 arg1Of production,the
R3427 T5645 T5644 arg1Of production,IL-1RA
R3428 T5651 T5648 arg2Of TSST-1,following
R3429 T5651 T5649 arg1Of TSST-1,GP
R3430 T5651 T5650 arg1Of TSST-1,+
R3431 T5652 T5653 arg1Of we,found
R3432 T5652 T5668 arg1Of we,compared
R3433 T5653 T5646 arg1Of found,However
R3434 T5653 T5647 arg1Of found,","
R3435 T5653 T5648 arg1Of found,following
R3436 T5653 T5663 arg1Of found,to
R3437 T5653 T5666 arg1Of found,","
R3438 T5653 T5667 arg1Of found,when
R3439 T5653 T5694 arg1Of found,(
R3440 T5656 T5653 arg2Of increase,found
R3441 T5656 T5654 arg1Of increase,a
R3442 T5656 T5655 arg1Of increase,synergistic
R3443 T5656 T5657 arg1Of increase,in
R3444 T5659 T5657 arg2Of production,in
R3445 T5659 T5658 arg1Of production,IL-1RA
R3446 T5659 T5660 arg1Of production,from
R3447 T5662 T5660 arg2Of h,from
R3448 T5662 T5661 arg1Of h,18
R3449 T5665 T5663 arg2Of h,to
R3450 T5665 T5664 arg1Of h,48
R3451 T5668 T5667 arg2Of compared,when
R3452 T5668 T5669 arg1Of compared,to
R3453 T5668 T5687 arg1Of compared,to
R3454 T5669 T5686 arg1Of to,or
R3455 T5670 T5669 arg2Of TSST-1,to
R3456 T5670 T5671 arg1Of TSST-1,(
R3457 T5672 T5671 arg2Of for,(
R3458 T5673 T5672 arg2Of instance,for
R3459 T5673 T5674 arg1Of instance,at
R3460 T5673 T5677 arg1Of instance,:
R3461 T5673 T5681 arg1Of instance,;
R3462 T5676 T5674 arg2Of h,at
R3463 T5676 T5675 arg1Of h,24
R3464 T5678 T5677 arg2Of n,:
R3465 T5678 T5679 arg1Of n,=
R3466 T5679 T5680 arg1Of =,6
R3467 T5682 T5681 arg2Of p,;
R3468 T5682 T5683 arg1Of p,=
R3469 T5682 T5684 arg1Of p,0.01
R3470 T5685 T5671 arg3Of ),(
R3471 T5687 T5686 arg2Of to,or
R3472 T5690 T5687 arg2Of value,to
R3473 T5690 T5688 arg1Of value,the
R3474 T5690 T5689 arg1Of value,theoretical
R3475 T5690 T5691 arg1Of value,of
R3476 T5693 T5691 arg2Of calc.,of
R3477 T5693 T5692 arg1Of calc.,GP/TSST-1
R3478 T5695 T5694 arg2Of from,(
R3479 T5700 T5695 arg2Of h,from
R3480 T5700 T5696 arg1Of h,18
R3481 T5700 T5697 arg1Of h,h
R3482 T5700 T5698 arg1Of h,to
R3483 T5700 T5699 arg1Of h,36
R3484 T5701 T5694 arg3Of ),(
R3485 T5705 T5702 arg2Of course,Over
R3486 T5705 T5703 arg1Of course,the
R3487 T5705 T5704 arg1Of course,time
R3488 T5705 T5706 arg1Of course,of
R3489 T5708 T5706 arg2Of h,of
R3490 T5708 T5707 arg1Of h,48
R3491 T5710 T5711 arg1Of GP,elevated
R3492 T5711 T5702 arg1Of elevated,Over
R3493 T5711 T5709 arg1Of elevated,","
R3494 T5711 T5717 arg1Of elevated,by
R3495 T5714 T5711 arg2Of amount,elevated
R3496 T5714 T5712 arg1Of amount,the
R3497 T5714 T5713 arg1Of amount,TSST-1-induced
R3498 T5714 T5715 arg1Of amount,of
R3499 T5716 T5715 arg2Of IL-1RA,of
R3500 T5719 T5718 arg1Of 200,approximately
R3501 T5720 T5717 arg2Of %,by
R3502 T5720 T5719 arg1Of %,200
R3503 T5720 T5721 arg1Of %,(
R3504 T5723 T5721 arg2Of 3B,(
R3505 T5723 T5722 arg1Of 3B,Fig.
R3506 T5724 T5721 arg3Of ),(
R3507 T5726 T5725 arg1Of correlation,Positive
R3508 T5726 T5727 arg1Of correlation,between
R3509 T5729 T5730 arg1Of IL-8,and
R3510 T5731 T5730 arg2Of IL-1RA,and
R3511 T5732 T5727 arg2Of productions,between
R3512 T5732 T5728 arg1Of productions,GP-induced
R3513 T5732 T5729 arg1Of productions,IL-8
R3514 T5732 T5731 arg1Of productions,IL-1RA
R3515 T5734 T5733 arg2Of stimulation,Following
R3516 T5734 T5735 arg1Of stimulation,with
R3517 T5736 T5735 arg2Of GP,with
R3518 T5736 T5737 arg1Of GP,(
R3519 T5739 T5737 arg2Of h,(
R3520 T5739 T5738 arg1Of h,24
R3521 T5740 T5737 arg3Of ),(
R3522 T5742 T5743 arg1Of we,observed
R3523 T5841 T5842 arg1Of TSST-1,or
R3524 T5743 T5733 arg1Of observed,Following
R3525 T5743 T5741 arg1Of observed,","
R3526 T5842 T5840 arg2Of or,with
R3527 T5746 T5743 arg2Of correlation,observed
R3528 T5746 T5744 arg1Of correlation,a
R3529 T5746 T5745 arg1Of correlation,positive
R3530 T5746 T5747 arg1Of correlation,between
R3531 T5748 T5749 arg1Of IL-8,and
R3532 T5749 T5747 arg2Of and,between
R3533 T5750 T5749 arg2Of IL-1RA,and
R3534 T5844 T5842 arg2Of calc.,or
R3535 T5753 T5754 arg1Of we,found
R3536 T5754 T5751 arg1Of found,Moreover
R3537 T5754 T5752 arg1Of found,","
R3538 T5754 T5760 arg1Of found,","
R3539 T5754 T5761 arg1Of found,since
R3540 T5756 T5754 arg2Of correlation,found
R3541 T5756 T5755 arg1Of correlation,this
R3542 T5756 T5758 arg1Of correlation,be
R3543 T5756 T5759 arg1Of correlation,dose-dependent
R3544 T5758 T5754 arg3Of be,found
R3545 T5758 T5757 arg1Of be,to
R3546 T5759 T5758 arg2Of dose-dependent,be
R3547 T5844 T5843 arg1Of calc.,GP/TSST-1
R3548 T5846 T5847 arg1Of GP,seemed
R3549 T5763 T5762 arg1Of μg,100
R3550 T5763 T5764 arg1Of μg,of
R3551 T5763 T5766 arg1Of μg,induced
R3552 T5765 T5764 arg2Of GP,of
R3553 T5766 T5761 arg2Of induced,since
R3554 T5846 T5849 arg1Of GP,exert
R3555 T5847 T5869 arg1Of seemed,but
R3556 T5768 T5766 arg2Of amounts,induced
R3557 T5768 T5767 arg1Of amounts,larger
R3558 T5768 T5769 arg1Of amounts,of
R3559 T5768 T5773 arg1Of amounts,than
R3560 T5768 T5777 arg1Of amounts,(
R3561 T5770 T5771 arg1Of IL-8,and
R3562 T5771 T5769 arg2Of and,of
R3563 T5772 T5771 arg2Of IL-1RA,and
R3564 T5849 T5847 arg2Of exert,seemed
R3565 T5776 T5773 arg2Of GP,than
R3566 T5776 T5774 arg1Of GP,1
R3567 T5776 T5775 arg1Of GP,μg
R3568 T5849 T5848 arg1Of exert,to
R3569 T5778 T5777 arg2Of n,(
R3570 T5778 T5779 arg1Of n,=
R3571 T5778 T5781 arg1Of n,","
R3572 T5779 T5780 arg1Of =,5
R3573 T5849 T5853 arg1Of exert,on
R3574 T5849 T5856 arg1Of exert,after
R3575 T5852 T5849 arg2Of effect,exert
R3576 T5782 T5781 arg2Of p,","
R3577 T5782 T5784 arg1Of p,0.002
R3578 T5782 T5785 arg1Of p,","
R3579 T5782 T5791 arg1Of p,","
R3580 T5782 T5792 arg1Of p,respectively
R3581 T5784 T5783 arg1Of 0.002,≤
R3582 T5788 T5789 arg1Of 0.9,and
R3583 T5789 T5785 arg2Of and,","
R3584 T5789 T5786 arg1Of and,r
R3585 T5789 T5787 arg1Of and,=
R3586 T5790 T5789 arg2Of 0.98,and
R3587 T5852 T5850 arg1Of effect,a
R3588 T5793 T5777 arg3Of ),(
R3589 T5852 T5851 arg1Of effect,synergistic
R3590 T5855 T5853 arg2Of secretion,on
R3591 T5795 T5794 arg2Of v,(
R3592 T5796 T5794 arg3Of ),(
R3593 T5797 T5794 arg1Of TNFα,(
R3594 T5798 T5800 arg1Of With,to
R3595 T5799 T5798 arg2Of respect,With
R3596 T5855 T5854 arg1Of secretion,TNFα
R3597 T5858 T5856 arg2Of h,after
R3598 T5802 T5798 arg3Of production,With
R3599 T5802 T5801 arg1Of production,TNFα
R3600 T5805 T5804 arg1Of μg,100
R3601 T5858 T5857 arg1Of h,36
R3602 T5858 T5859 arg1Of h,(
R3603 T5860 T5859 arg2Of n,(
R3604 T5805 T5806 arg1Of μg,of
R3605 T5805 T5808 arg1Of μg,yielded
R3606 T5805 T5817 arg1Of μg,compared
R3607 T5860 T5861 arg1Of n,=
R3608 T5860 T5863 arg1Of n,;
R3609 T5807 T5806 arg2Of GP,of
R3610 T5808 T5798 arg1Of yielded,With
R3611 T5808 T5803 arg1Of yielded,","
R3612 T5808 T5815 arg1Of yielded,","
R3613 T5808 T5816 arg1Of yielded,when
R3614 T5809 T5810 arg1Of minor,","
R3615 T5861 T5862 arg1Of =,3
R3616 T5864 T5863 arg2Of p,;
R3617 T5813 T5810 arg2Of distinguishable,","
R3618 T5813 T5811 arg1Of distinguishable,statistically
R3619 T5813 T5812 arg1Of distinguishable,not
R3620 T5814 T5808 arg2Of amounts,yielded
R3621 T5814 T5809 arg1Of amounts,minor
R3622 T5814 T5813 arg1Of amounts,distinguishable
R3623 T5817 T5816 arg2Of compared,when
R3624 T5817 T5818 arg1Of compared,to
R3625 T5864 T5865 arg1Of p,<
R3626 T5820 T5818 arg2Of control,to
R3627 T5820 T5819 arg1Of control,medium
R3628 T5864 T5866 arg1Of p,0.05
R3629 T5823 T5821 arg1Of LPS,GP
R3630 T5823 T5822 arg1Of LPS,+
R3631 T5823 T5824 arg1Of LPS,did
R3632 T5823 T5826 arg1Of LPS,change
R3633 T5823 T5831 arg1Of LPS,compared
R3634 T5826 T5824 arg2Of change,did
R3635 T5826 T5825 arg1Of change,not
R3636 T5826 T5830 arg1Of change,when
R3637 T5867 T5859 arg3Of ),(
R3638 T5829 T5826 arg2Of production,change
R3639 T5829 T5827 arg1Of production,the
R3640 T5829 T5828 arg1Of production,TNFα
R3641 T5831 T5830 arg2Of compared,when
R3642 T5831 T5832 arg1Of compared,to
R3643 T5869 T5838 arg1Of but,When
R3644 T5834 T5833 arg1Of supplementation,LPS
R3645 T5834 T5835 arg1Of supplementation,or
R3646 T5835 T5832 arg2Of or,to
R3647 T5837 T5835 arg2Of calc,or
R3648 T5837 T5836 arg1Of calc,GP/LPS
R3649 T5869 T5845 arg1Of but,","
R3650 T5869 T5868 arg1Of but,","
R3651 T5839 T5838 arg2Of combined,When
R3652 T5839 T5840 arg1Of combined,with
R3653 T5872 T5870 arg1Of enhancement,overall
R3654 T5872 T5871 arg1Of enhancement,an
R3655 T5872 T5873 arg1Of enhancement,of
R3656 T5872 T5877 arg1Of enhancement,was
R3657 T5872 T5878 arg2Of enhancement,observed
R3658 T5875 T5874 arg1Of 10,only
R3659 T5876 T5873 arg2Of %,of
R3660 T5876 T5875 arg1Of %,10
R3661 T5878 T5869 arg2Of observed,but
R3662 T5938 T5935 arg2Of TSST-1,following
R3663 T5878 T5877 arg2Of observed,was
R3664 T5938 T5936 arg1Of TSST-1,GP
R3665 T5938 T5937 arg1Of TSST-1,+
R3666 T5938 T5939 arg1Of TSST-1,at
R3667 T5941 T5940 arg1Of h,24
R3668 T5941 T5942 arg1Of h,and
R3669 T5878 T5879 arg1Of observed,(
R3670 T5942 T5939 arg2Of and,at
R3671 T5880 T5879 arg2Of p,(
R3672 T5944 T5942 arg2Of h,and
R3673 T5944 T5943 arg1Of h,36
R3674 T5947 T5946 arg2Of compared,when
R3675 T5947 T5948 arg1Of compared,to
R3676 T5880 T5881 arg1Of p,>
R3677 T5949 T5950 arg1Of TSST-1,or
R3678 T5880 T5882 arg1Of p,0.05
R3679 T5950 T5948 arg2Of or,to
R3680 T5952 T5950 arg2Of calc.,or
R3681 T5952 T5951 arg1Of calc.,GP/TSST-1
R3682 T5952 T5953 arg1Of calc.,(
R3683 T5880 T5883 arg1Of p,;
R3684 T5884 T5883 arg2Of data,;
R3685 T5954 T5953 arg2Of data,(
R3686 T5954 T5956 arg2Of data,shown
R3687 T5956 T5955 arg1Of shown,not
R3688 T5957 T5953 arg3Of ),(
R3689 T5959 T5960 arg1Of vii,)
R3690 T5884 T5886 arg2Of data,shown
R3691 T5886 T5885 arg1Of shown,not
R3692 T5961 T5962 arg1Of IL-2,","
R3693 T5962 T5964 arg1Of ",",","
R3694 T5963 T5962 arg2Of IL-12,","
R3695 T5886 T5887 arg1Of shown,in
R3696 T5964 T5966 arg1Of ",",","
R3697 T5965 T5964 arg2Of IL-4,","
R3698 T5888 T5887 arg2Of detail,in
R3699 T5966 T5968 arg1Of ",",","
R3700 T5967 T5966 arg2Of IL-10,","
R3701 T5968 T5958 arg1Of ",",(
R3702 T5968 T5959 arg1Of ",",vii
R3703 T5969 T5968 arg2Of TGFβ1,","
R3704 T5889 T5879 arg3Of ),(
R3705 T5971 T5970 arg1Of production,The
R3706 T5971 T5972 arg1Of production,of
R3707 T5971 T5983 arg1Of production,was
R3708 T5971 T5985 arg2Of production,induced
R3709 T5891 T5890 arg2Of vi,(
R3710 T5973 T5974 arg1Of IL-2,","
R3711 T5974 T5976 arg1Of ",",","
R3712 T5975 T5974 arg2Of IL-12,","
R3713 T5976 T5978 arg1Of ",",","
R3714 T5977 T5976 arg2Of IL-4,","
R3715 T5892 T5890 arg3Of ),(
R3716 T5978 T5980 arg1Of ",",and
R3717 T5979 T5978 arg2Of IL-10,","
R3718 T5980 T5972 arg2Of and,of
R3719 T5893 T5890 arg1Of IFNγ,(
R3720 T5981 T5980 arg2Of TGFβ,and
R3721 T5981 T5982 arg1Of TGFβ,1
R3722 T5896 T5894 arg1Of production,No
R3723 T5985 T5983 arg2Of induced,was
R3724 T5985 T5984 arg1Of induced,not
R3725 T5987 T5985 arg1Of GP,induced
R3726 T5987 T5986 arg2Of GP,by
R3727 T5988 T5989 arg1Of There,were
R3728 T5989 T5990 arg1Of were,also
R3729 T5896 T5895 arg1Of production,IFNγ
R3730 T5993 T5989 arg2Of differences,were
R3731 T5993 T5991 arg1Of differences,no
R3732 T5993 T5992 arg1Of differences,significant
R3733 T5993 T5994 arg1Of differences,between
R3734 T5896 T5897 arg1Of production,was
R3735 T5996 T5995 arg1Of control,medium
R3736 T5996 T5997 arg1Of control,","
R3737 T5997 T5999 arg1Of ",",","
R3738 T5896 T5898 arg1Of production,detectable
R3739 T5998 T5997 arg2Of LPS,","
R3740 T5897 T5899 arg1Of was,following
R3741 T5999 T6001 arg1Of ",",","
R3742 T6000 T5999 arg2Of TSST-1,","
R3743 T6001 T6003 arg1Of ",",","
R3744 T6002 T6001 arg2Of GP,","
R3745 T5898 T5897 arg2Of detectable,was
R3746 T6003 T6007 arg1Of ",",","
R3747 T5900 T5899 arg2Of treatment,following
R3748 T6006 T6003 arg2Of LPS,","
R3749 T6006 T6004 arg1Of LPS,GP
R3750 T6006 T6005 arg1Of LPS,+
R3751 T6007 T6010 arg1Of ",",and
R3752 T6009 T6007 arg2Of calc.,","
R3753 T6009 T6008 arg1Of calc.,GP/LPS
R3754 T6010 T5994 arg2Of and,between
R3755 T5900 T5901 arg1Of treatment,of
R3756 T5902 T5901 arg2Of PBMC,of
R3757 T6013 T6011 arg1Of TSST-1,GP
R3758 T6013 T6012 arg1Of TSST-1,+
R3759 T6013 T6014 arg1Of TSST-1,or
R3760 T5902 T5903 arg1Of PBMC,with
R3761 T6015 T6014 arg2Of GP/TSST-1,or
R3762 T6015 T6016 arg1Of GP/TSST-1,calc.
R3763 T5906 T5903 arg2Of GP,with
R3764 T6018 T6017 arg1Of 48,over
R3765 T6019 T6010 arg2Of h,and
R3766 T6019 T6013 arg1Of h,TSST-1
R3767 T6019 T6015 arg1Of h,GP/TSST-1
R3768 T6019 T6018 arg1Of h,48
R3769 T6019 T6020 arg1Of h,(
R3770 T6021 T6020 arg2Of data,(
R3771 T6021 T6023 arg2Of data,shown
R3772 T6023 T6022 arg1Of shown,not
R3773 T6024 T6020 arg3Of ),(
R3774 T5906 T5904 arg1Of GP,100
R3775 T5906 T5905 arg1Of GP,μg
R3776 T5907 T5908 arg1Of There,was
R3777 T5908 T5922 arg1Of was,","
R3778 T5908 T5923 arg1Of was,when
R3779 T5911 T5908 arg2Of increase,was
R3780 T5911 T5909 arg1Of increase,a
R3781 T5911 T5910 arg1Of increase,minor
R3782 T5911 T5912 arg1Of increase,in
R3783 T5914 T5912 arg2Of production,in
R3784 T5914 T5913 arg1Of production,IFNγ
R3785 T5914 T5915 arg1Of production,following
R3786 T5918 T5915 arg2Of LPS,following
R3787 T5918 T5916 arg1Of LPS,GP
R3788 T5918 T5917 arg1Of LPS,+
R3789 T5918 T5919 arg1Of LPS,at
R3790 T5921 T5919 arg2Of h,at
R3791 T5921 T5920 arg1Of h,36
R3792 T5924 T5923 arg2Of compared,when
R3793 T5924 T5925 arg1Of compared,to
R3794 T5924 T5945 arg1Of compared,","
R3795 T5924 T5946 arg1Of compared,when
R3796 T5926 T5927 arg1Of LPS,or
R3797 T5927 T5931 arg1Of or,and
R3798 T5929 T5927 arg2Of calc.,or
R3799 T5929 T5928 arg1Of calc.,GP/LPS
R3800 T5931 T5925 arg2Of and,to
R3801 T5931 T5930 arg1Of and,","
R3802 T5934 T5931 arg2Of down-regulation,and
R3803 T5934 T5932 arg1Of down-regulation,a
R3804 T5934 T5933 arg1Of down-regulation,slight
R3805 T5934 T5935 arg1Of down-regulation,following
R5157 T8173 T8174 arg1Of Role,of
R5158 T8173 T8181 arg1Of Role,in
R5159 T8173 T8197 arg1Of Role,by
R5160 T8175 T8176 arg1Of NFκB,","
R5161 T8176 T8178 arg1Of ",",and
R5162 T8177 T8176 arg2Of NFIL-6,","
R5163 T8178 T8174 arg2Of and,of
R5164 T8180 T8178 arg2Of binding,and
R5165 T8180 T8179 arg1Of binding,NFAT
R5166 T8182 T8183 arg1Of LPS-,","
R5167 T8183 T8185 arg1Of ",",","
R5168 T8184 T8183 arg2Of TSST-1-,","
R5169 T8185 T8187 arg1Of ",",","
R5170 T8186 T8185 arg2Of GP-,","
R5171 T8187 T8191 arg1Of ",",and
R5172 T8190 T8187 arg2Of LPS-,","
R5173 T8190 T8188 arg1Of LPS-,GP
R5174 T8190 T8189 arg1Of LPS-,+
R5175 T8191 T8181 arg2Of and,in
R5176 T8196 T8191 arg2Of expression,and
R5177 T8196 T8192 arg1Of expression,GP
R5178 T8196 T8193 arg1Of expression,+
R5179 T8196 T8194 arg1Of expression,TSST-1-induced
R5180 T8196 T8195 arg1Of expression,IL-1RA
R5181 T8199 T8197 arg2Of PBMC,by
R5182 T8199 T8198 arg1Of PBMC,human
R5183 T8201 T8202 arg1Of GP,induced
R5184 T8202 T8200 arg2Of induced,Because
R5185 T8204 T8202 arg2Of shifts,induced
R5186 T8204 T8203 arg1Of shifts,band
R5187 T8204 T8205 arg1Of shifts,to
R5188 T8206 T8207 arg1Of NFκB,","
R5189 T8207 T8209 arg1Of ",",and
R5190 T8208 T8207 arg2Of NFIL-6,","
R5191 T8209 T8213 arg1Of and,but
R5192 T8211 T8209 arg2Of sites,and
R5193 T8211 T8210 arg1Of sites,NFAT
R5194 T8213 T8205 arg2Of but,to
R5195 T8213 T8212 arg1Of but,","
R5196 T8215 T8216 arg1Of TNFα,","
R5197 T8216 T8218 arg1Of ",",or
R5198 T8217 T8216 arg2Of IL-6,","
R5199 T8218 T8213 arg2Of or,but
R5200 T8218 T8214 arg1Of or,no
R5201 T8219 T8218 arg2Of IFNγ,or
R5202 T8221 T8222 arg1Of we,hypothesized
R5203 T8222 T8200 arg1Of hypothesized,Because
R5204 T8222 T8220 arg1Of hypothesized,","
R5205 T8227 T8224 arg1Of factors,the
R5206 T8227 T8225 arg2Of factors,activated
R5207 T8227 T8226 arg1Of factors,transcription
R5208 T8227 T8228 arg1Of factors,might
R5209 T8227 T8229 arg1Of factors,bind
R5210 T8229 T8222 arg2Of bind,hypothesized
R5211 T8229 T8223 arg1Of bind,that
R5212 T8229 T8228 arg2Of bind,might
R5213 T8229 T8230 arg1Of bind,to
R5214 T8231 T8230 arg2Of sites,to
R5215 T8231 T8232 arg1Of sites,in
R5216 T8235 T8232 arg2Of promoter,in
R5217 T8235 T8233 arg1Of promoter,the
R5218 T8235 T8234 arg1Of promoter,IL-1RA
R5219 T8236 T8237 arg1Of We,investigated
R5220 T8239 T8238 arg1Of described,previoulsy
R5221 T8239 T8240 arg1Of described,and
R5222 T8242 T8240 arg2Of discovered,and
R5223 T8242 T8241 arg1Of discovered,newly
R5224 T8246 T8237 arg2Of sites,investigated
R5225 T8246 T8239 arg1Of sites,described
R5226 T8246 T8242 arg1Of sites,discovered
R5227 T8246 T8243 arg1Of sites,transcription
R5228 T8246 T8244 arg1Of sites,factor
R5229 T8246 T8245 arg1Of sites,binding
R5230 T8246 T8247 arg1Of sites,of
R5231 T8246 T8255 arg1Of sites,using
R5232 T8250 T8247 arg2Of promoter,of
R5233 T8250 T8248 arg1Of promoter,the
R5234 T8250 T8249 arg1Of promoter,IL-1RA
R5235 T8250 T8251 arg1Of promoter,(
R5236 T8252 T8251 arg2Of Table,(
R5237 T8252 T8253 arg1Of Table,1
R5238 T8254 T8251 arg3Of ),(
R5239 T8258 T8255 arg2Of OMIGA,using
R5240 T8258 T8256 arg1Of OMIGA,the
R5241 T8258 T8257 arg1Of OMIGA,program
R5242 T8258 T8259 arg1Of OMIGA,(
R5243 T8260 T8259 arg2Of v.1.1.3,(
R5244 T8260 T8261 arg1Of v.1.1.3,","
R5245 T8260 T8266 arg1Of v.1.1.3,","
R5246 T8260 T8267 arg1Of v.1.1.3,UK
R5247 T8263 T8261 arg2Of Molecular,","
R5248 T8263 T8262 arg1Of Molecular,Oxford
R5249 T8263 T8264 arg1Of Molecular,","
R5250 T8265 T8264 arg2Of Oxford,","
R5251 T8268 T8259 arg3Of ),(
R5252 T8274 T8269 arg1Of site,The
R5253 T8274 T8270 arg1Of site,LPS
R5254 T8274 T8271 arg1Of site,responsive
R5255 T8274 T8272 arg1Of site,κB
R5256 T8274 T8273 arg1Of site,consensus
R5257 T8274 T8275 arg1Of site,of
R5258 T8274 T8286 arg1Of site,displayed
R5259 T8276 T8275 arg2Of LRE-1,of
R5260 T8276 T8277 arg1Of LRE-1,(
R5261 T8276 T8283 arg1Of LRE-1,[
R5262 T8278 T8277 arg2Of between,(
R5263 T8279 T8280 arg1Of -84,and
R5264 T8280 T8278 arg2Of and,between
R5265 T8281 T8280 arg2Of -93,and
R5266 T8282 T8277 arg3Of ),(
R5267 T8284 T8283 arg2Of 30,[
R5268 T8285 T8283 arg3Of ],[
R5269 T8286 T8298 arg1Of displayed,","
R5270 T8286 T8299 arg1Of displayed,irrespective
R5271 T8288 T8287 arg1Of shifts,band
R5272 T8288 T8290 arg1Of shifts,but
R5273 T8290 T8286 arg2Of but,displayed
R5274 T8290 T8289 arg1Of but,","
R5275 T8293 T8290 arg2Of alterations,but
R5276 T8293 T8291 arg1Of alterations,no
R5277 T8293 T8292 arg1Of alterations,significant
R5278 T8293 T8294 arg1Of alterations,of
R5279 T8297 T8294 arg2Of activity,of
R5280 T8297 T8295 arg1Of activity,its
R5281 T8297 T8296 arg1Of activity,binding
R5282 T8299 T8300 arg1Of irrespective,of
R5283 T8302 T8300 arg2Of treatment,of
R5284 T8302 T8301 arg1Of treatment,the
R5285 T8302 T8303 arg1Of treatment,(
R5286 T8304 T8303 arg2Of data,(
R5287 T8304 T8306 arg2Of data,shown
R5288 T8306 T8305 arg1Of shown,not
R5289 T8307 T8303 arg3Of ),(
R5290 T8311 T8308 arg1Of site,A
R5291 T8311 T8309 arg1Of site,new
R5292 T8311 T8310 arg1Of site,κB3
R5293 T8311 T8312 arg1Of site,(
R5294 T8311 T8317 arg1Of site,within
R5295 T8311 T8323 arg1Of site,showed
R5296 T8313 T8314 arg1Of -100,and
R5297 T8314 T8312 arg2Of and,(
R5298 T8315 T8314 arg2Of -130,and
R5299 T8316 T8312 arg3Of ),(
R5300 T8319 T8317 arg2Of LRE-1,within
R5301 T8319 T8318 arg1Of LRE-1,the
R5302 T8319 T8320 arg1Of LRE-1,[
R5303 T8321 T8320 arg2Of 30,[
R5304 T8322 T8320 arg3Of ],[
R5305 T8323 T8336 arg1Of showed,but
R5306 T8325 T8323 arg2Of binding,showed
R5307 T8325 T8324 arg2Of binding,increased
R5308 T8325 T8326 arg2Of binding,induced
R5309 T8328 T8326 arg1Of TSST-1,induced
R5310 T8328 T8327 arg2Of TSST-1,by
R5311 T8328 T8329 arg1Of TSST-1,(
R5312 T8331 T8329 arg2Of %,(
R5313 T8331 T8330 arg1Of %,+30
R5314 T8331 T8332 arg1Of %,vs.
R5315 T8333 T8332 arg2Of control,vs.
R5316 T8334 T8329 arg3Of ),(
R5317 T8336 T8335 arg1Of but,","
R5318 T8336 T8365 arg1Of but,","
R5319 T8336 T8366 arg1Of but,when
R5320 T8338 T8337 arg1Of co-treatment,GP
R5321 T8338 T8339 arg1Of co-treatment,up-regulated
R5322 T8339 T8336 arg2Of up-regulated,but
R5323 T8339 T8360 arg1Of up-regulated,in
R5324 T8341 T8340 arg1Of LPS,the
R5325 T8341 T8342 arg1Of LPS,(
R5326 T8341 T8349 arg1Of LPS,and
R5327 T8344 T8342 arg2Of %,(
R5328 T8344 T8343 arg1Of %,+65
R5329 T8344 T8345 arg1Of %,vs.
R5330 T8346 T8345 arg2Of control,vs.
R5331 T8347 T8342 arg3Of ),(
R5332 T8349 T8339 arg2Of and,up-regulated
R5333 T8349 T8348 arg1Of and,-
R5334 T8351 T8352 arg1Of TSST-1,(
R5335 T8354 T8352 arg2Of %,(
R5336 T8354 T8353 arg1Of %,+110
R5337 T8354 T8355 arg1Of %,vs.
R5338 T8356 T8355 arg2Of control,vs.
R5339 T8357 T8352 arg3Of ),(
R5340 T8359 T8349 arg2Of binding,and
R5341 T8359 T8350 arg1Of binding,the
R5342 T8359 T8351 arg1Of binding,TSST-1
R5343 T8359 T8358 arg1Of binding,-induced
R5344 T8364 T8360 arg2Of fashion,in
R5345 T8364 T8361 arg1Of fashion,a
R5346 T8364 T8362 arg1Of fashion,superadditive
R5347 T8364 T8363 arg1Of fashion,synergistic
R5348 T8367 T8366 arg2Of compared,when
R5349 T8367 T8368 arg1Of compared,to
R5350 T8367 T8374 arg1Of compared,to
R5351 T8368 T8373 arg1Of to,as
R5352 T8370 T8368 arg2Of control,to
R5353 T8370 T8369 arg1Of control,medium
R5354 T8373 T8371 arg1Of as,as
R5355 T8373 T8372 arg1Of as,well
R5356 T8374 T8373 arg2Of to,as
R5357 T8375 T8376 arg1Of LPS,","
R5358 T8376 T8378 arg1Of ",",or
R5359 T8377 T8376 arg2Of TSST-1,","
R5360 T8378 T8380 arg1Of or,or
R5361 T8379 T8378 arg2Of GP,or
R5362 T8380 T8374 arg2Of or,to
R5363 T8383 T8380 arg2Of values,or
R5364 T8383 T8381 arg1Of values,the
R5365 T8383 T8382 arg1Of values,theoretical
R5366 T8383 T8384 arg1Of values,of
R5367 T8386 T8385 arg1Of calc.,GP/LPS
R5368 T8386 T8387 arg1Of calc.,or
R5369 T8387 T8384 arg2Of or,of
R5370 T8389 T8387 arg2Of calc.,or
R5371 T8389 T8388 arg1Of calc.,GP/TSST-1
R5372 T8389 T8390 arg1Of calc.,(
R5373 T8394 T8390 arg2Of 0.05,(
R5374 T8394 T8391 arg1Of 0.05,all
R5375 T8394 T8392 arg1Of 0.05,p
R5376 T8394 T8393 arg1Of 0.05,<
R5377 T8394 T8395 arg1Of 0.05,;
R5378 T8396 T8395 arg2Of Fig.,;
R5379 T8396 T8397 arg1Of Fig.,4
R5380 T8398 T8390 arg3Of ),(
R5381 T8399 T8400 arg1Of Binding,to
R5382 T8399 T8412 arg1Of Binding,was
R5383 T8399 T8414 arg2Of Binding,elevated
R5384 T8405 T8400 arg2Of site,to
R5385 T8405 T8401 arg1Of site,a
R5386 T8405 T8402 arg1Of site,new
R5387 T8405 T8403 arg1Of site,κB
R5388 T8405 T8404 arg1Of site,consensus
R5389 T8405 T8406 arg1Of site,(
R5390 T8407 T8406 arg2Of between,(
R5391 T8408 T8409 arg1Of -266,and
R5392 T8409 T8407 arg2Of and,between
R5393 T8410 T8409 arg2Of -280,and
R5394 T8411 T8406 arg3Of ),(
R5395 T8414 T8412 arg2Of elevated,was
R5396 T8414 T8413 arg1Of elevated,significantly
R5397 T8414 T8415 arg1Of elevated,for
R5398 T8418 T8415 arg2Of TSST-1,for
R5399 T8418 T8416 arg1Of TSST-1,GP
R5400 T8418 T8417 arg1Of TSST-1,+
R5401 T8418 T8419 arg1Of TSST-1,(
R5402 T8420 T8419 arg2Of p,(
R5403 T8420 T8421 arg1Of p,<
R5404 T8420 T8422 arg1Of p,0.05
R5405 T8420 T8423 arg1Of p,;
R5406 T8424 T8423 arg2Of data,;
R5407 T8424 T8426 arg2Of data,shown
R5408 T8426 T8425 arg1Of shown,not
R5409 T8427 T8419 arg3Of ),(
R5410 T8429 T8430 arg1Of LPS-,","
R5411 T8430 T8432 arg1Of ",",and
R5412 T8431 T8430 arg2Of TSST-1-,","
R5413 T8432 T8434 arg1Of and,+
R5414 T8433 T8432 arg2Of GP,and
R5415 T8434 T8428 arg1Of +,The
R5416 T8434 T8447 arg1Of +,was
R5417 T8434 T8448 arg2Of +,down-regulated
R5418 T8436 T8434 arg2Of binding,+
R5419 T8436 T8435 arg1Of binding,LPS-induced
R5420 T8436 T8437 arg1Of binding,to
R5421 T8441 T8437 arg2Of site,to
R5422 T8441 T8438 arg1Of site,the
R5423 T8441 T8439 arg1Of site,new
R5424 T8441 T8440 arg1Of site,κB2/3
R5425 T8441 T8442 arg1Of site,(
R5426 T8443 T8444 arg1Of -288,and
R5427 T8444 T8442 arg2Of and,(
R5428 T8445 T8444 arg2Of -302,and
R5429 T8446 T8442 arg3Of ),(
R5430 T8448 T8447 arg2Of down-regulated,was
R5431 T8448 T8449 arg1Of down-regulated,by
R5432 T8448 T8453 arg1Of down-regulated,in
R5433 T8451 T8450 arg1Of 20–35,about
R5434 T8452 T8449 arg2Of %,by
R5435 T8452 T8451 arg1Of %,20–35
R5436 T8454 T8453 arg2Of comparison,in
R5437 T8454 T8455 arg1Of comparison,with
R5438 T8457 T8455 arg2Of control,with
R5439 T8457 T8456 arg1Of control,medium
R5440 T8457 T8458 arg1Of control,(
R5441 T8459 T8458 arg2Of p,(
R5442 T8459 T8460 arg1Of p,<
R5443 T8459 T8461 arg1Of p,0.05
R5444 T8459 T8462 arg1Of p,;
R5445 T8463 T8462 arg2Of data,;
R5446 T8463 T8465 arg2Of data,shown
R5447 T8465 T8464 arg1Of shown,not
R5448 T8466 T8458 arg3Of ),(
R5449 T8469 T8467 arg1Of site,The
R5450 T8469 T8468 arg1Of site,NFIL-6
R5451 T8469 T8470 arg1Of site,(
R5452 T8469 T8475 arg1Of site,close
R5453 T8469 T8481 arg1Of site,showed
R5454 T8471 T8472 arg1Of -147,and
R5455 T8472 T8470 arg2Of and,(
R5456 T8473 T8472 arg2Of -170,and
R5457 T8474 T8470 arg3Of ),(
R5458 T8475 T8476 arg1Of close,to
R5459 T8477 T8476 arg2Of LRE-2,to
R5460 T8477 T8478 arg1Of LRE-2,[
R5461 T8479 T8478 arg2Of "31,32",[
R5462 T8480 T8478 arg3Of ],[
R5463 T8481 T8499 arg1Of showed,(
R5464 T8483 T8481 arg2Of up-regulation,showed
R5465 T8483 T8482 arg1Of up-regulation,an
R5466 T8483 T8484 arg1Of up-regulation,of
R5467 T8483 T8494 arg1Of up-regulation,","
R5468 T8483 T8495 arg1Of up-regulation,ranging
R5469 T8485 T8486 arg1Of binding,for
R5470 T8485 T8491 arg1Of binding,vs.
R5471 T8488 T8489 arg1Of compounds,and
R5472 T8489 T8486 arg2Of and,for
R5473 T8489 T8487 arg1Of and,all
R5474 T8490 T8489 arg2Of combinations,and
R5475 T8491 T8484 arg2Of vs.,of
R5476 T8493 T8491 arg2Of control,vs.
R5477 T8493 T8492 arg1Of control,medium
R5478 T8495 T8496 arg1Of ranging,from
R5479 T8498 T8496 arg2Of %,from
R5480 T8498 T8497 arg1Of %,25–110
R5481 T8500 T8499 arg2Of p,(
R5482 T8500 T8501 arg1Of p,<
R5483 T8500 T8502 arg1Of p,0.05
R5484 T8503 T8499 arg3Of ),(
R5485 T8506 T8509 arg1Of GP,induced
R5486 T8509 T8504 arg1Of induced,Further
R5487 T8509 T8505 arg1Of induced,","
R5488 T8509 T8507 arg1Of induced,+
R5489 T8509 T8508 arg1Of induced,TSST-1
R5490 T8509 T8517 arg1Of induced,in
R5491 T8512 T8509 arg2Of binding,induced
R5492 T8512 T8510 arg1Of binding,an
R5493 T8512 T8511 arg2Of binding,increased
R5494 T8512 T8513 arg1Of binding,to
R5495 T8516 T8513 arg2Of site,to
R5496 T8516 T8514 arg1Of site,the
R5497 T8516 T8515 arg1Of site,NFIL-6
R5498 T8517 T8519 arg1Of in,with
R5499 T8518 T8517 arg2Of comparison,in
R5500 T8520 T8521 arg1Of TSST-1,(
R5501 T8520 T8524 arg1Of TSST-1,or
R5502 T8522 T8521 arg2Of 1.3fold,(
R5503 T8523 T8521 arg3Of ),(
R5504 T8524 T8517 arg3Of or,in
R5505 T8524 T8533 arg1Of or,","
R5506 T8524 T8534 arg1Of or,(
R5507 T8525 T8524 arg2Of GP,or
R5508 T8525 T8526 arg1Of GP,(
R5509 T8527 T8526 arg2Of 1.6fold,(
R5510 T8527 T8528 arg1Of 1.6fold,;
R5511 T8529 T8528 arg2Of p,;
R5512 T8529 T8530 arg1Of p,<
R5513 T8529 T8531 arg1Of p,0.05
R5514 T8532 T8526 arg3Of ),(
R5515 T8535 T8534 arg2Of data,(
R5516 T8535 T8537 arg2Of data,shown
R5517 T8537 T8536 arg1Of shown,not
R5518 T8538 T8534 arg3Of ),(
R5519 T8542 T8539 arg1Of site,A
R5520 T8542 T8540 arg1Of site,new
R5521 T8542 T8541 arg1Of site,binding
R5522 T8542 T8543 arg1Of site,for
R5523 T8542 T8545 arg1Of site,was
R5524 T8542 T8546 arg2Of site,found
R5525 T8542 T8548 arg1Of site,distal
R5526 T8542 T8560 arg1Of site,displaying
R5527 T8542 T8574 arg1Of site,compared
R5528 T8544 T8543 arg2Of NFATP2/3,for
R5529 T8546 T8545 arg2Of found,was
R5530 T8546 T8554 arg1Of found,","
R5531 T8546 T8555 arg1Of found,between
R5532 T8546 T8559 arg1Of found,","
R5533 T8546 T8560 modOf found,displaying
R5534 T8546 T8572 arg1Of found,","
R5535 T8546 T8573 arg1Of found,when
R5536 T8548 T8546 arg3Of distal,found
R5537 T8548 T8547 arg1Of distal,more
R5538 T8548 T8549 arg1Of distal,of
R5539 T8553 T8549 arg2Of site,of
R5540 T8553 T8550 arg1Of site,the
R5541 T8553 T8551 arg1Of site,transcription
R5542 T8553 T8552 arg1Of site,start
R5543 T8556 T8557 arg1Of -471,and
R5544 T8557 T8555 arg2Of and,between
R5545 T8558 T8557 arg2Of -490,and
R5546 T8560 T8561 arg1Of displaying,again
R5547 T8564 T8560 arg2Of increase,displaying
R5548 T8564 T8562 arg1Of increase,a
R5549 T8564 T8563 arg1Of increase,substantial
R5550 T8564 T8565 arg1Of increase,of
R5551 T8566 T8565 arg2Of binding,of
R5552 T8566 T8567 arg1Of binding,for
R5553 T8569 T8570 arg1Of compounds,and
R5554 T8570 T8567 arg2Of and,for
R5555 T8570 T8568 arg1Of and,all
R5556 T8571 T8570 arg2Of combinations,and
R5557 T8574 T8573 arg2Of compared,when
R5558 T8574 T8575 arg1Of compared,to
R5559 T8577 T8575 arg2Of control,to
R5560 T8577 T8576 arg1Of control,medium
R5561 T8577 T8578 arg1Of control,(
R5562 T8579 T8578 arg2Of p,(
R5563 T8579 T8580 arg1Of p,<
R5564 T8579 T8581 arg1Of p,0.05
R5565 T8582 T8578 arg3Of ),(
R5566 T8584 T8583 arg2Of addition,In
R5567 T8586 T8587 arg1Of binding,to
R5568 T8586 T8591 arg1Of binding,following
R5569 T8590 T8587 arg2Of site,to
R5570 T8590 T8588 arg1Of site,the
R5571 T8590 T8589 arg1Of site,NFATP2/3
R5572 T8591 T8592 arg1Of following,both
R5573 T8591 T8593 arg1Of following,","
R5574 T8594 T8591 arg2Of GP,following
R5575 T8594 T8595 arg1Of GP,+
R5576 T8596 T8597 arg1Of LPS,(
R5577 T8596 T8602 arg1Of LPS,and
R5578 T8599 T8597 arg2Of of,(
R5579 T8599 T8598 arg1Of of,1.4fold
R5580 T8600 T8599 arg2Of GP,of
R5581 T8601 T8597 arg3Of ),(
R5582 T8602 T8615 arg1Of and,was
R5583 T8602 T8616 arg2Of and,elevated
R5584 T8605 T8602 arg2Of TSST-1,and
R5585 T8605 T8603 arg1Of TSST-1,GP
R5586 T8605 T8604 arg1Of TSST-1,+
R5587 T8605 T8606 arg1Of TSST-1,(
R5588 T8607 T8606 arg2Of 1.5fold,(
R5589 T8607 T8608 arg1Of 1.5fold,of
R5590 T8607 T8610 arg1Of 1.5fold,","
R5591 T8607 T8611 arg1Of 1.5fold,1.25fold
R5592 T8609 T8608 arg2Of GP,of
R5593 T8611 T8612 arg1Of 1.25fold,of
R5594 T8613 T8612 arg2Of TSST-1,of
R5595 T8614 T8606 arg3Of ),(
R5596 T8616 T8586 arg2Of elevated,binding
R5597 T8616 T8615 arg2Of elevated,was
R5598 T8616 T8617 arg1Of elevated,(
R5599 T8616 T8626 arg1Of elevated,but
R5600 T8616 T8628 arg1Of elevated,in
R5601 T8616 T8633 arg1Of elevated,","
R5602 T8618 T8617 arg2Of p,(
R5603 T8618 T8619 arg1Of p,<
R5604 T8618 T8620 arg1Of p,0.05
R5605 T8618 T8621 arg1Of p,;
R5606 T8622 T8621 arg2Of Fig.,;
R5607 T8622 T8623 arg1Of Fig.,5
R5608 T8624 T8617 arg3Of ),(
R5609 T8626 T8625 arg1Of but,","
R5610 T8628 T8627 arg1Of in,only
R5611 T8632 T8628 arg2Of manner,in
R5612 T8632 T8629 arg1Of manner,an
R5613 T8632 T8630 arg1Of manner,additive
R5614 T8632 T8631 arg1Of manner,synergistic
R5615 T8637 T8586 arg1Of results,binding
R5616 T8637 T8634 arg1Of results,i.e.
R5617 T8637 T8635 arg1Of results,the
R5618 T8637 T8636 arg1Of results,experimental
R5619 T8637 T8638 arg1Of results,were
R5620 T8637 T8640 arg1Of results,different
R5621 T8638 T8583 arg1Of were,In
R5622 T8638 T8585 arg1Of were,","
R5623 T8638 T8586 modOf were,binding
R5624 T8638 T8639 arg1Of were,not
R5625 T8640 T8638 arg2Of different,were
R5626 T8640 T8641 arg1Of different,from
R5627 T8644 T8641 arg2Of values,from
R5628 T8644 T8642 arg1Of values,the
R5629 T8644 T8643 arg1Of values,theoretical
R5630 T8644 T8645 arg1Of values,(
R5631 T8646 T8645 arg2Of calc.,(
R5632 T8647 T8645 arg3Of ),(
R6304 T9645 T9646 arg1Of GP,modulated
R6305 T9646 T9651 arg1Of modulated,towards
R6306 T9650 T9646 arg2Of ratio,modulated
R6307 T9650 T9647 arg1Of ratio,the
R6308 T9650 T9648 arg1Of ratio,TSST-1-induced
R6309 T9650 T9649 arg1Of ratio,IL-1β/IL-1RA
R6310 T9654 T9651 arg2Of phenotype,towards
R6311 T9654 T9652 arg1Of phenotype,an
R6312 T9654 T9653 arg1Of phenotype,anti-inflammatory
R6313 T9658 T9655 arg2Of approach,In
R6314 T9658 T9656 arg1Of approach,a
R6315 T9658 T9657 arg1Of approach,simplified
R6316 T9660 T9661 arg1Of IL-1β,and
R6317 T9661 T9663 arg1Of and,might
R6318 T9661 T9664 arg1Of and,represent
R6319 T9662 T9661 arg2Of IL-1RA,and
R6320 T9664 T9655 arg1Of represent,In
R6321 T9664 T9659 arg1Of represent,","
R6322 T9664 T9663 arg2Of represent,might
R6323 T9666 T9664 arg2Of sides,represent
R6324 T9666 T9665 arg1Of sides,two
R6325 T9666 T9667 arg1Of sides,of
R6326 T9666 T9670 arg1Of sides,","
R6327 T9669 T9667 arg2Of coin,of
R6328 T9669 T9668 arg1Of coin,a
R6329 T9672 T9671 arg1Of pro-,i.e.
R6330 T9672 T9673 arg1Of pro-,or
R6331 T9673 T9670 arg2Of or,","
R6332 T9675 T9673 arg2Of action,or
R6333 T9675 T9674 arg1Of action,anti-inflammatory
R6334 T9678 T9679 arg1Of we,applied
R6335 T9679 T9676 arg1Of applied,Therefore
R6336 T9679 T9677 arg1Of applied,","
R6337 T9679 T9683 arg1Of applied,as
R6338 T9682 T9679 arg2Of ratio,applied
R6339 T9682 T9680 arg1Of ratio,the
R6340 T9682 T9681 arg1Of ratio,IL-1β/IL-1RA
R6341 T9685 T9683 arg2Of indicator,as
R6342 T9685 T9684 arg1Of indicator,an
R6343 T9685 T9686 arg1Of indicator,of
R6344 T9688 T9686 arg2Of degree,of
R6345 T9688 T9687 arg1Of degree,the
R6346 T9688 T9689 arg1Of degree,of
R6347 T9690 T9689 arg2Of inflammation,of
R6348 T9693 T9694 arg1Of LPS,and
R6349 T9694 T9699 arg1Of and,resulted
R6350 T9694 T9701 arg1Of and,generating
R6351 T9698 T9694 arg2Of treatments,and
R6352 T9698 T9695 arg1Of treatments,GP
R6353 T9698 T9696 arg1Of treatments,+
R6354 T9698 T9697 arg1Of treatments,LPS
R6355 T9699 T9691 arg1Of resulted,Both
R6356 T9699 T9692 arg1Of resulted,","
R6357 T9699 T9700 arg1Of resulted,in
R6358 T9701 T9700 arg2Of generating,in
R6359 T9701 T9706 arg1Of generating,at
R6360 T9703 T9701 arg2Of IL-1β,generating
R6361 T9703 T9702 arg1Of IL-1β,more
R6362 T9703 T9704 arg1Of IL-1β,than
R6363 T9705 T9704 arg2Of IL-1RA,than
R6364 T9709 T9706 arg2Of points,at
R6365 T9709 T9707 arg1Of points,early
R6366 T9709 T9708 arg1Of points,time
R6367 T9709 T9710 arg1Of points,","
R6368 T9714 T9712 arg1Of 24,up
R6369 T9714 T9713 arg1Of 24,to
R6370 T9715 T9710 arg2Of h,","
R6371 T9715 T9711 arg1Of h,i.e.
R6372 T9715 T9714 arg1Of h,24
R6373 T9717 T9718 arg1Of LPS,vs.
R6374 T9719 T9718 arg2Of GP,vs.
R6375 T9721 T9716 arg2Of LPS,Comparing
R6376 T9721 T9717 arg1Of LPS,LPS
R6377 T9721 T9720 arg1Of LPS,+
R6378 T9723 T9716 arg1Of we,Comparing
R6379 T9723 T9724 arg1Of we,did
R6380 T9723 T9726 arg1Of we,find
R6381 T9726 T9716 modOf find,Comparing
R6382 T9726 T9722 arg1Of find,","
R6383 T9726 T9724 arg2Of find,did
R6384 T9726 T9725 arg1Of find,not
R6385 T9726 T9729 arg1Of find,over
R6386 T9728 T9726 arg2Of alterations,find
R6387 T9728 T9727 arg1Of alterations,substantial
R6388 T9732 T9729 arg2Of course,over
R6389 T9732 T9730 arg1Of course,a
R6390 T9732 T9731 arg1Of course,time
R6391 T9732 T9733 arg1Of course,of
R6392 T9735 T9733 arg2Of h,of
R6393 T9735 T9734 arg1Of h,48
R6394 T9735 T9736 arg1Of h,in
R6395 T9739 T9736 arg2Of ratio,in
R6396 T9739 T9737 arg1Of ratio,the
R6397 T9739 T9738 arg1Of ratio,IL-1β/IL-1RA
R6398 T9739 T9740 arg1Of ratio,","
R6399 T9745 T9741 arg1Of –,only
R6400 T9745 T9742 arg1Of –,a
R6401 T9745 T9743 arg1Of –,–
R6402 T9745 T9744 arg1Of –,non-significant
R6403 T9747 T9746 arg1Of higher,2.5fold
R6404 T9748 T9740 arg2Of ratio,","
R6405 T9748 T9745 arg1Of ratio,–
R6406 T9748 T9747 arg1Of ratio,higher
R6407 T9748 T9749 arg1Of ratio,at
R6408 T9751 T9749 arg2Of h,at
R6409 T9751 T9750 arg1Of h,6
R6410 T9752 T9754 arg1Of With,to
R6411 T9753 T9752 arg2Of respect,With
R6412 T9755 T9756 arg1Of TSST-1,or
R6413 T9756 T9752 arg3Of or,With
R6414 T9759 T9756 arg2Of value,or
R6415 T9759 T9757 arg1Of value,the
R6416 T9759 T9758 arg1Of value,theoretical
R6417 T9759 T9760 arg1Of value,of
R6418 T9766 T9760 arg2Of TSST-1,of
R6419 T9766 T9761 arg1Of TSST-1,GP/TSST-1
R6420 T9766 T9762 arg1Of TSST-1,calc.
R6421 T9766 T9763 arg1Of TSST-1,vs.
R6422 T9766 T9764 arg1Of TSST-1,GP
R6423 T9766 T9765 arg1Of TSST-1,+
R6424 T9768 T9769 arg1Of we,observed
R6425 T9769 T9752 arg1Of observed,With
R6426 T9769 T9767 arg1Of observed,","
R6427 T9769 T9776 arg1Of observed,","
R6428 T9769 T9777 arg1Of observed,as
R6429 T9769 T9794 arg1Of observed,","
R6430 T9773 T9769 arg2Of action,observed
R6431 T9773 T9770 arg1Of action,a
R6432 T9773 T9771 arg1Of action,pronounced
R6433 T9773 T9772 arg1Of action,anti-inflammatory
R6434 T9773 T9774 arg1Of action,of
R6435 T9775 T9774 arg2Of GP,of
R6436 T9778 T9777 arg2Of demonstrated,as
R6437 T9778 T9786 arg1Of demonstrated,at
R6438 T9782 T9781 arg1Of 10–100,about
R6439 T9785 T9778 arg1Of ratio,demonstrated
R6440 T9785 T9779 arg2Of ratio,by
R6441 T9785 T9780 arg1Of ratio,an
R6442 T9785 T9782 arg1Of ratio,10–100
R6443 T9785 T9783 arg1Of ratio,fold
R6444 T9785 T9784 arg2Of ratio,reduced
R6445 T9788 T9787 arg1Of h,18
R6446 T9788 T9789 arg1Of h,and
R6447 T9789 T9786 arg2Of and,at
R6448 T9791 T9789 arg2Of h,and
R6449 T9791 T9790 arg1Of h,24
R6450 T9791 T9792 arg1Of h,of
R6451 T9793 T9792 arg2Of incubation,of
R6452 T9798 T9769 arg3Of production,observed
R6453 T9798 T9795 arg1Of production,i.e.
R6454 T9798 T9796 arg1Of production,a
R6455 T9798 T9797 arg1Of production,higher
R6456 T9798 T9799 arg1Of production,of
R6457 T9798 T9801 arg1Of production,than
R6458 T9798 T9804 arg1Of production,(
R6459 T9800 T9799 arg2Of IL-1RA,of
R6460 T9802 T9801 arg2Of of,than
R6461 T9803 T9802 arg2Of IL-1β,of
R6462 T9809 T9808 arg1Of both,;
R6463 T9812 T9804 arg2Of 0.05,(
R6464 T9812 T9805 arg1Of 0.05,n
R6465 T9812 T9806 arg1Of 0.05,=
R6466 T9812 T9807 arg1Of 0.05,3
R6467 T9812 T9809 arg1Of 0.05,both
R6468 T9812 T9810 arg1Of 0.05,p
R6469 T9812 T9811 arg1Of 0.05,<
R6470 T9812 T9813 arg1Of 0.05,;
R6471 T9814 T9813 arg2Of Fig.,;
R6472 T9814 T9815 arg1Of Fig.,6
R6473 T9816 T9804 arg3Of ),(
R6474 T9819 T9817 arg1Of relevance,A
R6475 T9819 T9818 arg1Of relevance,biological
R6476 T9819 T9820 arg1Of relevance,of
R6477 T9819 T9823 arg1Of relevance,was
R6478 T9819 T9824 arg2Of relevance,suggested
R6479 T9819 T9844 arg1Of relevance,compared
R6480 T9822 T9820 arg2Of result,of
R6481 T9822 T9821 arg1Of result,this
R6482 T9824 T9823 arg2Of suggested,was
R6483 T9824 T9839 arg1Of suggested,following
R6484 T9824 T9843 arg1Of suggested,when
R6485 T9827 T9824 arg1Of decrease,suggested
R6486 T9827 T9825 arg2Of decrease,by
R6487 T9827 T9826 arg1Of decrease,a
R6488 T9827 T9828 arg1Of decrease,of
R6489 T9827 T9835 arg1Of decrease,from
R6490 T9832 T9828 arg2Of release,of
R6491 T9832 T9829 arg1Of release,the
R6492 T9832 T9830 arg1Of release,IL-1
R6493 T9832 T9831 arg1Of release,dependent
R6494 T9832 T9833 arg1Of release,of
R6495 T9834 T9833 arg2Of IL-2,of
R6496 T9838 T9835 arg2Of cells,from
R6497 T9838 T9836 arg1Of cells,murine
R6498 T9838 T9837 arg1Of cells,EL-4
R6499 T9842 T9839 arg2Of TSST-1,following
R6500 T9842 T9840 arg1Of TSST-1,GP
R6501 T9842 T9841 arg1Of TSST-1,+
R6502 T9844 T9843 arg2Of compared,when
R6503 T9844 T9845 arg1Of compared,to
R6504 T9846 T9847 arg1Of TSST-1,or
R6505 T9847 T9845 arg2Of or,to
R6506 T9847 T9850 arg1Of or,(
R6507 T9849 T9847 arg2Of calc.,or
R6508 T9849 T9848 arg1Of calc.,GP/TSST-1
R6509 T9851 T9850 arg2Of data,(
R6510 T9851 T9853 arg2Of data,shown
R6511 T9853 T9852 arg1Of shown,not
R6512 T9853 T9854 arg1Of shown,in
R6513 T9855 T9854 arg2Of detail,in
R6514 T9855 T9856 arg1Of detail,","
R6515 T9857 T9856 arg2Of n,","
R6516 T9857 T9862 arg1Of n,<
R6517 T9859 T9858 arg1Of 4,=
R6518 T9859 T9860 arg1Of 4,;
R6519 T9861 T9860 arg2Of p,;
R6520 T9862 T9859 arg1Of <,4
R6521 T9862 T9863 arg1Of <,0.07
R6522 T9864 T9850 arg3Of ),(
R6858 T10536 T10537 arg1Of Inhibition,of
R6859 T10536 T10540 arg1Of Inhibition,led
R6860 T10539 T10537 arg2Of factors,of
R6861 T10539 T10538 arg1Of factors,transcription
R6862 T10540 T10541 arg1Of led,to
R6863 T10544 T10541 arg2Of levels,to
R6864 T10544 T10542 arg2Of levels,reduced
R6865 T10544 T10543 arg1Of levels,IL-1RA
R6866 T10546 T10545 arg1Of inhibitors,Pharmacological
R6867 T10546 T10547 arg1Of inhibitors,were
R6868 T10546 T10548 arg2Of inhibitors,used
R6869 T10546 T10550 arg1Of inhibitors,demonstrate
R6870 T10548 T10547 arg2Of used,were
R6871 T10550 T10548 arg3Of demonstrate,used
R6872 T10550 T10549 arg1Of demonstrate,to
R6873 T10555 T10552 arg1Of sites,the
R6874 T10555 T10553 arg1Of sites,transcription
R6875 T10555 T10554 arg1Of sites,factor
R6876 T10555 T10556 arg1Of sites,within
R6877 T10555 T10560 arg1Of sites,are
R6878 T10555 T10561 arg1Of sites,relevant
R6879 T10559 T10556 arg2Of promoter,within
R6880 T10559 T10557 arg1Of promoter,the
R6881 T10559 T10558 arg1Of promoter,IL-1RA
R6882 T10560 T10550 arg2Of are,demonstrate
R6883 T10560 T10551 arg1Of are,that
R6884 T10561 T10560 arg2Of relevant,are
R6885 T10561 T10562 arg1Of relevant,for
R6886 T10564 T10562 arg2Of induction,for
R6887 T10564 T10563 arg1Of induction,the
R6888 T10564 T10565 arg1Of induction,of
R6889 T10564 T10567 arg1Of induction,by
R6890 T10566 T10565 arg2Of IL-1RA,of
R6891 T10568 T10567 arg2Of GP,by
R6892 T10570 T10569 arg2Of expected,As
R6893 T10573 T10572 arg1Of inhibition,an
R6894 T10573 T10574 arg1Of inhibition,of
R6895 T10573 T10576 arg1Of inhibition,via
R6896 T10573 T10589 arg1Of inhibition,via
R6897 T10573 T10594 arg1Of inhibition,could
R6898 T10573 T10596 arg1Of inhibition,be
R6899 T10573 T10597 arg2Of inhibition,overruled
R6900 T10575 T10574 arg2Of NFκB,of
R6901 T10577 T10578 arg1Of CAPE,[
R6902 T10577 T10581 arg1Of CAPE,and
R6903 T10579 T10578 arg2Of 35,[
R6904 T10580 T10578 arg3Of ],[
R6905 T10581 T10576 arg2Of and,via
R6906 T10582 T10583 arg1Of CyA,","
R6907 T10583 T10581 arg2Of ",",and
R6908 T10583 T10585 arg1Of ",",via
R6909 T10584 T10583 arg2Of NFAT,","
R6910 T10586 T10587 arg1Of CyA,and
R6911 T10587 T10585 arg2Of and,via
R6912 T10588 T10587 arg2Of NFIL-6,and
R6913 T10590 T10589 arg2Of CHX,via
R6914 T10590 T10591 arg1Of CHX,[
R6915 T10592 T10591 arg2Of 36,[
R6916 T10593 T10591 arg3Of ],[
R6917 T10597 T10569 arg1Of overruled,As
R6918 T10597 T10571 arg1Of overruled,","
R6919 T10597 T10594 arg2Of overruled,could
R6920 T10597 T10595 arg1Of overruled,not
R6921 T10597 T10596 arg2Of overruled,be
R6922 T10597 T10600 arg1Of overruled,","
R6923 T10597 T10601 modOf overruled,leading
R6924 T10599 T10597 arg1Of GP,overruled
R6925 T10599 T10598 arg2Of GP,by
R6926 T10601 T10602 arg1Of leading,to
R6927 T10606 T10603 arg1Of activity,a
R6928 T10606 T10604 arg1Of activity,down-regulated
R6929 T10606 T10605 arg1Of activity,binding
R6930 T10606 T10607 arg1Of activity,of
R6931 T10606 T10611 arg1Of activity,to
R6932 T10606 T10616 arg1Of activity,and
R6933 T10610 T10607 arg2Of factors,of
R6934 T10610 T10608 arg1Of factors,the
R6935 T10610 T10609 arg1Of factors,transcription
R6936 T10614 T10611 arg2Of sites,to
R6937 T10614 T10612 arg1Of sites,the
R6938 T10614 T10613 arg1Of sites,IL-1RA
R6939 T10616 T10602 arg2Of and,to
R6940 T10616 T10615 arg1Of and,","
R6941 T10618 T10616 arg2Of reduction,and
R6942 T10618 T10617 arg1Of reduction,a
R6943 T10618 T10619 arg1Of reduction,of
R6944 T10621 T10620 arg1Of mRNA,IL-1RA
R6945 T10621 T10622 arg1Of mRNA,and
R6946 T10622 T10619 arg2Of and,of
R6947 T10625 T10622 arg2Of levels,and
R6948 T10625 T10623 arg1Of levels,IL-1RA
R6949 T10625 T10624 arg1Of levels,protein
R6950 T10625 T10626 arg1Of levels,(
R6951 T10627 T10626 arg2Of Fig.,(
R6952 T10627 T10628 arg1Of Fig.,7
R6953 T10629 T10626 arg3Of ),(
R6954 T10631 T10630 arg1Of extent,The
R6955 T10631 T10632 arg1Of extent,of
R6956 T10631 T10634 arg1Of extent,in
R6957 T10631 T10637 arg1Of extent,is
R6958 T10631 T10639 arg2Of extent,shown
R6959 T10631 T10652 arg2Of extent,summarized
R6960 T10633 T10632 arg2Of reduction,of
R6961 T10636 T10634 arg2Of binding,in
R6962 T10636 T10635 arg1Of binding,NFATP2/3
R6963 T10639 T10640 arg1Of shown,in
R6964 T10639 T10643 arg1Of shown,(
R6965 T10639 T10650 arg1Of shown,and
R6966 T10642 T10640 arg2Of autoradiogram,in
R6967 T10642 T10641 arg1Of autoradiogram,an
R6968 T10645 T10643 arg2Of 7A,(
R6969 T10645 T10644 arg1Of 7A,Fig.
R6970 T10645 T10646 arg1Of 7A,","
R6971 T10648 T10646 arg2Of side,","
R6972 T10648 T10647 arg1Of side,left
R6973 T10649 T10643 arg3Of ),(
R6974 T10650 T10637 arg2Of and,is
R6975 T10650 T10638 arg1Of and,exemplarily
R6976 T10652 T10650 arg2Of summarized,and
R6977 T10652 T10651 arg1Of summarized,graphically
R6978 T10652 T10653 arg1Of summarized,(
R6979 T10654 T10653 arg2Of n,(
R6980 T10654 T10655 arg1Of n,=
R6981 T10654 T10657 arg1Of n,","
R6982 T10654 T10660 arg1Of n,","
R6983 T10655 T10656 arg1Of =,4
R6984 T10659 T10657 arg2Of 7A,","
R6985 T10659 T10658 arg1Of 7A,Fig.
R6986 T10662 T10660 arg2Of side,","
R6987 T10662 T10661 arg1Of side,right
R6988 T10663 T10653 arg3Of ),(
R6989 T10665 T10664 arg1Of results,The
R6990 T10665 T10666 arg1Of results,for
R6991 T10665 T10673 arg1Of results,were
R6992 T10665 T10674 arg1Of results,similar
R6993 T10668 T10669 arg1Of NFκB,and
R6994 T10670 T10669 arg2Of NFIL-6,and
R6995 T10672 T10666 arg2Of sites,for
R6996 T10672 T10667 arg1Of sites,the
R6997 T10672 T10668 arg1Of sites,NFκB
R6998 T10672 T10670 arg1Of sites,NFIL-6
R6999 T10672 T10671 arg1Of sites,binding
R7000 T10674 T10673 arg2Of similar,were
R7001 T10674 T10675 arg1Of similar,(
R7002 T10676 T10675 arg2Of data,(
R7003 T10676 T10678 arg2Of data,shown
R7004 T10678 T10677 arg1Of shown,not
R7005 T10679 T10675 arg3Of ),(
R7006 T10684 T10681 arg1Of amount,the
R7007 T10684 T10682 arg1Of amount,highest
R7008 T10684 T10683 arg1Of amount,IL-1RA
R7009 T10684 T10685 arg1Of amount,was
R7010 T10684 T10686 arg2Of amount,found
R7011 T10686 T10680 arg2Of found,Because
R7012 T10686 T10685 arg2Of found,was
R7013 T10686 T10687 arg1Of found,at
R7014 T10689 T10687 arg2Of h,at
R7015 T10689 T10688 arg1Of h,24
R7016 T10691 T10692 arg1Of mRNA,was
R7017 T10691 T10693 arg2Of mRNA,examined
R7018 T10693 T10680 arg1Of examined,Because
R7019 T10693 T10690 arg1Of examined,","
R7020 T10693 T10692 arg2Of examined,was
R7021 T10693 T10694 arg1Of examined,following
R7022 T10697 T10695 arg1Of inhibition,1
R7023 T10697 T10696 arg1Of inhibition,h
R7024 T10697 T10698 arg1Of inhibition,and
R7025 T10698 T10694 arg2Of and,following
R7026 T10700 T10698 arg2Of h,and
R7027 T10700 T10699 arg1Of h,18
R7028 T10700 T10701 arg1Of h,of
R7029 T10702 T10701 arg2Of GP,of
R7030 T10705 T10703 arg1Of gel,A
R7031 T10705 T10704 arg1Of gel,representative
R7032 T10705 T10706 arg1Of gel,demonstrating
R7033 T10705 T10720 arg1Of gel,is
R7034 T10705 T10721 arg2Of gel,displayed
R7035 T10708 T10706 arg2Of decrease,demonstrating
R7036 T10708 T10707 arg1Of decrease,a
R7037 T10708 T10709 arg1Of decrease,in
R7038 T10708 T10712 arg1Of decrease,after
R7039 T10708 T10714 arg1Of decrease,with
R7040 T10711 T10709 arg2Of mRNA,in
R7041 T10711 T10710 arg1Of mRNA,IL-1RA
R7042 T10713 T10712 arg2Of inhibition,after
R7043 T10715 T10716 arg1Of CAPE,","
R7044 T10716 T10718 arg1Of ",",and
R7045 T10717 T10716 arg2Of CyA,","
R7046 T10718 T10714 arg2Of and,with
R7047 T10719 T10718 arg2Of CHX,and
R7048 T10721 T10720 arg2Of displayed,is
R7049 T10721 T10722 arg1Of displayed,in
R7050 T10724 T10722 arg2Of 7B,in
R7051 T10724 T10723 arg1Of 7B,Fig.
R7052 T10724 T10725 arg1Of 7B,(
R7053 T10726 T10725 arg2Of n,(
R7054 T10726 T10727 arg1Of n,=
R7055 T10726 T10728 arg1Of n,4
R7056 T10729 T10725 arg3Of ),(
R7057 T10731 T10730 arg2Of addition,In
R7058 T10736 T10733 arg1Of levels,corresponding
R7059 T10736 T10734 arg1Of levels,IL-1RA
R7060 T10736 T10735 arg1Of levels,protein
R7061 T10736 T10737 arg1Of levels,after
R7062 T10736 T10742 arg1Of levels,are
R7063 T10736 T10743 arg2Of levels,shown
R7064 T10739 T10737 arg2Of h,after
R7065 T10739 T10738 arg1Of h,24
R7066 T10739 T10740 arg1Of h,of
R7067 T10741 T10740 arg2Of GP,of
R7068 T10743 T10730 arg1Of shown,In
R7069 T10743 T10732 arg1Of shown,","
R7070 T10743 T10742 arg2Of shown,are
R7071 T10743 T10744 arg1Of shown,in
R7072 T10746 T10744 arg2Of 7C,in
R7073 T10746 T10745 arg1Of 7C,Fig.
R7074 T10746 T10747 arg1Of 7C,(
R7075 T10748 T10747 arg2Of n,(
R7076 T10748 T10749 arg1Of n,=
R7077 T10748 T10750 arg1Of n,3
R7078 T10751 T10747 arg3Of ),(
R7079 T10755 T10754 arg1Of inhibition,NFκB
R7080 T10755 T10756 arg1Of inhibition,by
R7081 T10755 T10758 arg1Of inhibition,was
R7082 T10755 T10760 arg1Of inhibition,pronounced
R7083 T10757 T10756 arg2Of CAPE,by
R7084 T10758 T10752 arg1Of was,Altogether
R7085 T10758 T10753 arg1Of was,","
R7086 T10758 T10761 arg1Of was,at
R7087 T10758 T10769 arg1Of was,whereas
R7088 T10760 T10758 arg2Of pronounced,was
R7089 T10760 T10759 arg1Of pronounced,more
R7090 T10764 T10762 arg1Of activity,the
R7091 T10764 T10763 arg1Of activity,binding
R7092 T10764 T10765 arg1Of activity,and
R7093 T10765 T10761 arg2Of and,at
R7094 T10767 T10765 arg2Of transcription,and
R7095 T10767 T10766 arg1Of transcription,the
R7096 T10769 T10768 arg1Of whereas,","
R7097 T10770 T10771 arg1Of CyA,and
R7098 T10771 T10774 arg1Of and,led
R7099 T10772 T10771 arg2Of CHX,and
R7100 T10774 T10769 arg2Of led,whereas
R7101 T10774 T10773 arg1Of led,mainly
R7102 T10774 T10775 arg1Of led,to
R7103 T10779 T10775 arg2Of release,to
R7104 T10779 T10776 arg1Of release,a
R7105 T10779 T10777 arg2Of release,decreased
R7106 T10779 T10778 arg1Of release,IL-1RA
R13188 T19275 T19276 arg1Of Immuno,(
R13189 T19277 T19276 arg2Of Dot,(
R13190 T19278 T19276 arg3Of ),(
R13191 T19279 T19275 arg1Of blot,Immuno
R13192 T19282 T19280 arg1Of proteins,The
R13193 T19282 T19281 arg1Of proteins,nuclear
R13194 T19282 T19283 arg1Of proteins,were
R13195 T19282 T19284 arg2Of proteins,blotted
R13196 T19284 T19283 arg2Of blotted,were
R13197 T19284 T19285 arg1Of blotted,onto
R16991 T25020 T25043 arg1Of observed,","
R16999 T25029 T25037 arg1Of demonstrated,at
R17005 T25036 T25034 arg1Of ratio,fold
R17006 T25036 T25035 arg2Of ratio,reduced
R17007 T25039 T25038 arg1Of h,18
R17008 T25039 T25040 arg1Of h,and
R17009 T25040 T25037 arg2Of and,at
R17010 T25042 T25040 arg2Of h,and
R17011 T25042 T25041 arg1Of h,24
R17013 T25047 T25044 arg1Of production,i.e.
R17014 T25047 T25045 arg1Of production,a
R17015 T25047 T25046 arg1Of production,higher
R17016 T25047 T25048 arg1Of production,of
R17017 T25047 T25050 arg1Of production,than
R17018 T25047 T25053 arg1Of production,(
R17019 T25049 T25048 arg2Of IL-1RA,of
R17020 T25051 T25050 arg2Of of,than
R17021 T25052 T25051 arg2Of IL-1β,of
R17022 T25056 T25053 arg2Of p,(
R17023 T25056 T25054 arg1Of p,*
R17024 T25056 T25055 arg1Of p,=
R17025 T25056 T25057 arg1Of p,<
R17026 T25056 T25058 arg1Of p,0.05
R17027 T25059 T25053 arg3Of ),(
R17028 T25060 T25061 arg1Of Data,are
R17029 T25060 T25062 arg2Of Data,shown
R17030 T25062 T25061 arg2Of shown,are
R17031 T25062 T25063 arg1Of shown,as
R17032 T25066 T25063 arg2Of SEM,as
R17033 T25066 T25064 arg1Of SEM,mean
R17034 T25066 T25065 arg1Of SEM,±
R17035 T25066 T25067 arg1Of SEM,(
R17036 T25068 T25067 arg2Of n,(
R17037 T25068 T25069 arg1Of n,=
R17038 T25068 T25070 arg1Of n,3
R17039 T25071 T25067 arg3Of ),(
R418 T1289 T1290 arg1Of β-1→3-D-glucans,occur
R419 T1289 T1300 arg1Of β-1→3-D-glucans,can
R420 T1289 T1301 arg1Of β-1→3-D-glucans,be
R421 T1289 T1302 arg2Of β-1→3-D-glucans,secreted
R422 T1290 T1291 arg1Of occur,as
R423 T1290 T1299 arg1Of occur,or
R424 T1294 T1291 arg2Of component,as
R425 T1294 T1292 arg1Of component,a
R426 T1294 T1293 arg1Of component,principal
R427 T1294 T1295 arg1Of component,of
R428 T1298 T1295 arg2Of walls,of
R429 T1298 T1296 arg1Of walls,microbial
R430 T1298 T1297 arg1Of walls,cell
R431 T1302 T1299 arg2Of secreted,or
R432 T1302 T1300 arg2Of secreted,can
R433 T1302 T1301 arg2Of secreted,be
R434 T1302 T1303 arg1Of secreted,from
R435 T1303 T1304 arg1Of from,both
R436 T1306 T1307 arg1Of non-pathogenic,and
R9309 T14184 T14185 arg1Of GP,(
R9310 T14184 T14188 arg1Of GP,and
R9312 T14186 T14185 arg2Of PI3K,(
R9314 T14187 T14185 arg3Of ),(
R9315 T14188 T14183 arg2Of and,between
R9316 T14189 T14188 arg2Of LPS,and
R9317 T14189 T14190 arg1Of LPS,(
R9320 T14193 T14190 arg2Of signaling,(
R9322 T14193 T14191 arg1Of signaling,mitogen-activated
R9323 T14193 T14192 arg1Of signaling,kinase
R9324 T14194 T14190 arg3Of ),(
R9325 T14196 T14195 arg1Of idea,This
R9326 T14196 T14197 arg1Of idea,may
R9327 T14196 T14198 arg1Of idea,be

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T8093 16730-16747 Antecedent denotes κB consensus site
T8092 16841-16844 Anaphor denotes its
R5152 T8092 T8093 boundBy its,κB consensus site

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T311 914-918 Protein denotes IL-8
T312 1004-1008 Protein denotes IL-8
T313 1034-1057 Protein denotes IL-1receptor antagonist
T314 1058-1060 Protein denotes RA
T315 1162-1166 Protein denotes IL-8
T316 1274-1280 Protein denotes IL-1RA
T25543 23575-23581 Protein denotes IL-1RA
T25542 23528-23534 Protein denotes NFIL-6
T25541 23519-23523 Protein denotes NFAT
T25540 23429-23434 Protein denotes GAPDH
T25539 23374-23380 Protein denotes IL-1RA
T25538 23345-23351 Protein denotes NFIL-6
T25537 23336-23340 Protein denotes NFAT
T25536 22882-22888 Protein denotes IL-1RA
T25535 22856-22862 Protein denotes NFIL-6
T25534 22847-22851 Protein denotes NFAT
T24868 21479-21484 Protein denotes IL-1β
T24867 21464-21470 Protein denotes IL-1RA
T24866 21300-21306 Protein denotes TSST-1
T24865 21279-21285 Protein denotes TSST-1
T24864 21266-21272 Protein denotes TSST-1
T24863 21226-21232 Protein denotes IL-1RA
T24862 21220-21225 Protein denotes IL-1β
T24861 21107-21113 Protein denotes IL-1RA
T24860 21096-21101 Protein denotes IL-1β
T24859 21027-21033 Protein denotes TSST-1
T24858 21014-21020 Protein denotes TSST-1
T24857 20977-20983 Protein denotes TSST-1
T24856 20919-20925 Protein denotes IL-1RA
T24855 20913-20918 Protein denotes IL-1β
T24854 20879-20885 Protein denotes TSST-1
T24853 20855-20861 Protein denotes TSST-1
T24852 20827-20833 Protein denotes IL-1RA
T24851 20821-20826 Protein denotes IL-1β
T24234 19648-19654 Protein denotes TSST-1
T24233 19609-19615 Protein denotes TSST-1
T24232 19379-19385 Protein denotes TSST-1
T24231 19300-19306 Protein denotes IL-1RA
T24230 19255-19259 Protein denotes NFAT
T24229 19177-19183 Protein denotes TSST-1
T24228 19160-19166 Protein denotes TSST-1
T24227 19085-19091 Protein denotes TSST-1
T24226 19017-19023 Protein denotes TSST-1
T24225 18953-18959 Protein denotes IL-1RA
T24224 18896-18902 Protein denotes TSST-1
T21515 9947-9953 Protein denotes TSST-1
T21514 9765-9771 Protein denotes TSST-1
T21513 9739-9745 Protein denotes TSST-1
T21512 9676-9682 Protein denotes TSST-1
T21511 9661-9667 Protein denotes TSST-1
T21510 9641-9647 Protein denotes TSST-1
T21509 9506-9509 Protein denotes p50
T21508 9497-9500 Protein denotes p65
T21507 9483-9487 Protein denotes IL-8
T21506 9375-9379 Protein denotes IL-8
T21505 9356-9362 Protein denotes NFIL-6
T21504 9336-9340 Protein denotes NFAT
T21503 9241-9245 Protein denotes IL-8
T21502 9232-9236 Protein denotes IL-6
T21501 9226-9230 Protein denotes TNFα
T21500 9220-9224 Protein denotes IFNγ
T21499 9172-9176 Protein denotes IL-8
T21498 9157-9163 Protein denotes NFIL-6
T21497 9145-9149 Protein denotes NFAT
T21496 9002-9008 Protein denotes NFIL-6
T21495 8987-8991 Protein denotes NFAT
T19768 38342-38346 Protein denotes IL-1
T19767 38298-38302 Protein denotes IL-2
T19766 38228-38234 Protein denotes TGFβ 1
T19765 38156-38160 Protein denotes IL-8
T19764 38145-38151 Protein denotes IL-1RA
T19763 38070-38074 Protein denotes IL-6
T19762 38061-38065 Protein denotes IL-1
T19761 38055-38059 Protein denotes TNFα
T19760 38049-38053 Protein denotes IFNγ
T18800 36506-36511 Protein denotes Oct-1
T18799 36400-36402 Protein denotes 50
T18798 36396-36399 Protein denotes p65
T18289 35528-35532 Protein denotes NFAT
T18288 35417-35421 Protein denotes TNFα
T18287 35359-35363 Protein denotes IFNγ
T18286 34889-34893 Protein denotes IL-6
T18285 34880-34884 Protein denotes IFNγ
T17124 32946-32952 Protein denotes IL-1RA
T17123 32940-32945 Protein denotes IL-1β
T17122 32654-32660 Protein denotes IL-1RA
T17121 32457-32463 Protein denotes IL-1RA
T17120 32427-32433 Protein denotes TSST-1
T17119 32377-32383 Protein denotes TSST-1
T12411 32024-32030 Protein denotes IL-1RA
T12410 31698-31702 Protein denotes NFAT
T12365 28476-28480 Protein denotes IL-6
T12364 28466-28471 Protein denotes IL-1β
T12363 28386-28392 Protein denotes IL-1RA
T12362 28380-28385 Protein denotes IL-1β
T12361 28365-28371 Protein denotes TSST-1
T12360 28201-28207 Protein denotes TSST-1
T12359 27682-27688 Protein denotes IL-1RA
T12358 27651-27655 Protein denotes IL-8
T12357 27548-27576 Protein denotes p38 mitogen-activated kinase
T12356 27512-27516 Protein denotes TNFα
T12355 27503-27507 Protein denotes IFNγ
T12354 27388-27394 Protein denotes TSST-1
T12353 27347-27351 Protein denotes TNFα
T12352 27222-27242 Protein denotes Toll-like receptor 4
T12351 27161-27167 Protein denotes TSST-1
T12350 27076-27082 Protein denotes TSST-1
T12349 26946-26952 Protein denotes IL-1RA
T12348 26933-26937 Protein denotes IL-8
T12347 26822-26828 Protein denotes IL-1RA
T12346 26708-26714 Protein denotes IL-1RA
T12345 26543-26549 Protein denotes IL-1RA
T12344 26513-26519 Protein denotes IL-1RA
T12343 26482-26488 Protein denotes NFIL-6
T12342 26473-26477 Protein denotes NFAT
T12341 26421-26427 Protein denotes IL-1RA
T12340 26412-26416 Protein denotes IL-6
T12339 26406-26410 Protein denotes IFNγ
T12338 26388-26392 Protein denotes NFAT
T12337 26254-26260 Protein denotes NFIL-6
T12336 26248-26249 Protein denotes 3
T12335 26241-26247 Protein denotes NFATP2
T12334 25923-25929 Protein denotes IL-1RA
T12333 25842-25848 Protein denotes IL-1RA
T12332 25811-25816 Protein denotes IL-1β
T12331 25771-25777 Protein denotes TSST-1
T12330 25583-25588 Protein denotes IL-1β
T12329 25574-25578 Protein denotes TNFα
T12328 25499-25502 Protein denotes p65
T12327 25451-25455 Protein denotes IL-8
T12326 25409-25413 Protein denotes IL-8
T12325 25381-25387 Protein denotes NFATc2
T12324 25363-25369 Protein denotes NFIL-6
T12323 25355-25358 Protein denotes p65
T12322 25283-25287 Protein denotes IL-8
T12321 25249-25253 Protein denotes IL-8
T12320 25188-25190 Protein denotes 50
T12319 25184-25187 Protein denotes p65
T12318 25154-25156 Protein denotes 65
T12317 25150-25153 Protein denotes p65
T12316 25095-25099 Protein denotes IL-8
T12315 25000-25004 Protein denotes IL-8
T12314 24966-24969 Protein denotes p50
T12313 24936-24939 Protein denotes p65
T12312 24797-24803 Protein denotes IL-1RA
T12311 24778-24782 Protein denotes IL-8
T12310 24668-24674 Protein denotes IL-1RA
T12309 24659-24663 Protein denotes IL-8
T12308 24473-24477 Protein denotes NFAT
T12307 24383-24387 Protein denotes NFAT
T12306 24301-24305 Protein denotes NFAT
T12305 24289-24295 Protein denotes NFIL-6
T8113 18336-18342 Protein denotes TSST-1
T8112 18301-18307 Protein denotes TSST-1
T4995 16160-16166 Protein denotes TSST-1
T4994 16147-16153 Protein denotes TSST-1
T4973 15291-15295 Protein denotes TNFα
T4972 15142-15146 Protein denotes TNFα
T4971 15121-15125 Protein denotes TNFα
T4970 15044-15050 Protein denotes IL-1RA
T4969 15035-15039 Protein denotes IL-8
T4968 14924-14930 Protein denotes IL-1RA
T4967 14915-14919 Protein denotes IL-8
T4966 14814-14820 Protein denotes IL-1RA
T4965 14805-14809 Protein denotes IL-8
T4964 14725-14731 Protein denotes IL-1RA
T4963 14700-14706 Protein denotes TSST-1
T4962 14620-14626 Protein denotes TSST-1
T4961 14539-14545 Protein denotes TSST-1
T4960 14485-14491 Protein denotes IL-1RA
T4959 14443-14449 Protein denotes TSST-1
T4958 14400-14406 Protein denotes IL-1RA
T4957 14164-14170 Protein denotes IL-1RA
T4956 14158-14162 Protein denotes IL-8
T4955 14143-14149 Protein denotes IL-1RA
T4954 14096-14102 Protein denotes TSST-1
T4953 14083-14089 Protein denotes TSST-1
T4952 14059-14065 Protein denotes TSST-1
T4951 14028-14032 Protein denotes IL-8
T4950 13936-13940 Protein denotes IL-8
T4949 13775-13779 Protein denotes IL-8
T4948 13731-13735 Protein denotes IL-8
T4947 13626-13632 Protein denotes TSST-1
T4946 13613-13619 Protein denotes TSST-1
T4945 13589-13595 Protein denotes TSST-1
T4944 13564-13568 Protein denotes IL-6
T4943 13500-13504 Protein denotes IL-6
T4942 13436-13440 Protein denotes IL-6
T4941 13397-13401 Protein denotes IL-6
T4940 12146-12151 Protein denotes IL-1β
T4939 12121-12127 Protein denotes TSST-1
T4938 12039-12045 Protein denotes TSST-1
T4937 12001-12007 Protein denotes TSST-1
T4936 11932-11937 Protein denotes IL-1β
T4935 11889-11895 Protein denotes TSST-1
T4934 11813-11818 Protein denotes IL-1β
T4933 11704-11709 Protein denotes IL-1β
T4932 11685-11690 Protein denotes IL-1β
T4931 11671-11677 Protein denotes TSST-1
T4930 11095-11099 Protein denotes IFNγ
T4929 11089-11093 Protein denotes IL-6
T4928 11083-11087 Protein denotes IL-8
T4927 11077-11081 Protein denotes TNFα
T4926 10981-10985 Protein denotes IFNγ
T4925 10972-10976 Protein denotes IL-6
T4924 10966-10970 Protein denotes IL-8
T4923 10960-10964 Protein denotes TNFα
T4922 10891-10897 Protein denotes TSST-1
T4921 10861-10867 Protein denotes TSST-1
T317 1385-1391 Protein denotes TSST-1
T318 1477-1483 Protein denotes TSST-1
T319 1513-1519 Protein denotes NFIL-6
T320 1524-1528 Protein denotes NFAT
T321 1567-1573 Protein denotes IL-1RA
T322 1615-1621 Protein denotes TSST-1
T323 1669-1674 Protein denotes IL-1β
T324 1679-1683 Protein denotes IL-6
T325 1732-1738 Protein denotes TSST-1
T326 1747-1752 Protein denotes IL-1β
T327 1753-1759 Protein denotes IL-1RA
T328 1851-1857 Protein denotes TSST-1
T329 1867-1871 Protein denotes IL-1
T330 1896-1900 Protein denotes IL-2
T331 2102-2108 Protein denotes IL-1RA
T332 2199-2205 Protein denotes IL-1RA
T1155 2732-2740 Protein denotes Dectin-1
T1156 3007-3015 Protein denotes Dectin-1
T1157 3042-3046 Protein denotes TNFα
T1158 3055-3075 Protein denotes Toll-like receptor 2
T1159 3100-3105 Protein denotes MyD88
T1160 3202-3208 Protein denotes NFIL-6
T1161 3461-3465 Protein denotes IL-1
T1162 3467-3471 Protein denotes IL-6
T1163 3473-3477 Protein denotes TNFα
T1164 3549-3555 Protein denotes IL-1RA
T1165 3565-3569 Protein denotes IL-1
T1166 3771-3775 Protein denotes IL-8
T1167 4917-4923 Protein denotes TSST-1
T1168 5048-5052 Protein denotes TNFα
T1169 5054-5059 Protein denotes IL-1β
T1170 5061-5065 Protein denotes IL-6
T1171 5067-5071 Protein denotes IL-8
T1172 5076-5082 Protein denotes IL-1RA
T1173 5108-5112 Protein denotes IFNγ
T1174 5114-5118 Protein denotes IL-2
T1175 5120-5124 Protein denotes IL-4
T1176 5126-5131 Protein denotes IL-10
T1177 5133-5138 Protein denotes IL-12
T1178 5143-5148 Protein denotes TGFβ1
T1179 5192-5196 Protein denotes TNFα
T1180 5266-5270 Protein denotes IL-8
T1181 5308-5312 Protein denotes IFNγ
T1182 5371-5375 Protein denotes IL-6
T1183 5446-5452 Protein denotes IL-1RA
T1184 5508-5514 Protein denotes IL-1RA
T1185 5627-5633 Protein denotes IL-1RA
T1186 5822-5828 Protein denotes IL-1RA
T3251 6689-6692 Protein denotes p65
T3252 6718-6721 Protein denotes p50
T3253 6731-6734 Protein denotes p52
T3254 6863-6867 Protein denotes TNFα
T3255 6934-6940 Protein denotes TSST-1
T3256 6979-6985 Protein denotes TSST-1
T3257 7063-7069 Protein denotes TSST-1
T3258 7100-7106 Protein denotes TSST-1
T3259 7130-7136 Protein denotes TSST-1
T3260 7235-7239 Protein denotes NFAT
T3261 7261-7265 Protein denotes IFNγ
T3262 7308-7312 Protein denotes NFAT
T3263 7359-7365 Protein denotes NFATc2
T3264 7392-7398 Protein denotes NFATc1
T3236 5877-5883 Protein denotes NFIL-6
T3237 5888-5892 Protein denotes NFAT
T3238 5916-5920 Protein denotes TNFα
T3239 5922-5926 Protein denotes IL-6
T3240 5931-5935 Protein denotes IFNγ
T3241 5996-6002 Protein denotes TSST-1
T3242 6026-6032 Protein denotes TSST-1
T3243 6098-6104 Protein denotes NFIL-6
T3244 6187-6191 Protein denotes TNFα
T3245 6223-6227 Protein denotes IL-8
T3246 6263-6267 Protein denotes IL-6
T3247 6397-6403 Protein denotes TSST-1
T3248 6475-6479 Protein denotes IL-8
T3249 6544-6547 Protein denotes p65
T3250 6574-6577 Protein denotes p50
T18284 34874-34878 Protein denotes IL-8
T18283 34868-34872 Protein denotes TNFα
T9620 20743-20749 Protein denotes TSST-1
T9619 20730-20736 Protein denotes TSST-1
T9618 20706-20712 Protein denotes TSST-1
T9617 20663-20667 Protein denotes IL-2
T9616 20637-20641 Protein denotes IL-1
T9615 20526-20531 Protein denotes IL-1β
T9614 20511-20517 Protein denotes IL-1RA
T9613 20332-20338 Protein denotes TSST-1
T9612 20310-20316 Protein denotes TSST-1
T9611 20272-20278 Protein denotes TSST-1
T9610 20186-20192 Protein denotes IL-1RA
T9609 20180-20185 Protein denotes IL-1β
T9608 20032-20038 Protein denotes IL-1RA
T9607 20021-20026 Protein denotes IL-1β
T9606 19899-19905 Protein denotes IL-1RA
T9605 19893-19898 Protein denotes IL-1β
T9604 19784-19790 Protein denotes IL-1RA
T9603 19774-19779 Protein denotes IL-1β
T9602 19696-19702 Protein denotes IL-1RA
T9601 19690-19695 Protein denotes IL-1β
T9600 19675-19681 Protein denotes TSST-1
T23011 12854-12860 Protein denotes IL-1RA
T23010 12824-12830 Protein denotes TSST-1
T23009 12786-12792 Protein denotes TSST-1
T23008 12748-12754 Protein denotes IL-1RA
T23007 12652-12657 Protein denotes IL-1β
T23006 12623-12629 Protein denotes TSST-1
T23005 12536-12542 Protein denotes TSST-1
T23004 12512-12518 Protein denotes TSST-1
T23003 12480-12485 Protein denotes IL-1β
T23002 12398-12404 Protein denotes TSST-1
T23001 12385-12391 Protein denotes TSST-1
T23000 12297-12302 Protein denotes IL-1β
T22999 12267-12273 Protein denotes TSST-1
T22998 12243-12249 Protein denotes TSST-1
T22997 12189-12194 Protein denotes IL-1β
T19219 37240-37246 Protein denotes NFATc1
T19218 37212-37218 Protein denotes NFATc2
T19217 37186-37191 Protein denotes c-rel
T19216 37127-37130 Protein denotes p52
T19215 37101-37104 Protein denotes p65
T19214 37073-37076 Protein denotes p50
T19213 36967-36972 Protein denotes c-Rel
T19212 36944-36947 Protein denotes p52
T19211 36686-36690 Protein denotes NFAT
T8111 17906-17912 Protein denotes TSST-1
T8110 17832-17838 Protein denotes TSST-1
T8109 17468-17474 Protein denotes TSST-1
T8108 17423-17429 Protein denotes TSST-1
T8107 17291-17297 Protein denotes TSST-1
T8106 17230-17236 Protein denotes TSST-1
T8105 17096-17102 Protein denotes TSST-1
T8104 17000-17006 Protein denotes TSST-1
T8103 16620-16626 Protein denotes IL-1RA
T8102 16503-16509 Protein denotes IL-1RA
T8101 16413-16417 Protein denotes IFNγ
T8100 16405-16409 Protein denotes IL-6
T8099 16399-16403 Protein denotes TNFα
T8098 16297-16303 Protein denotes IL-1RA
T8097 16282-16288 Protein denotes TSST-1
T8096 16249-16255 Protein denotes TSST-1
T8095 16227-16231 Protein denotes NFAT
T8094 16216-16222 Protein denotes NFIL-6
T22395 10604-10607 Protein denotes p65
T22394 10599-10602 Protein denotes p50
T22393 10529-10534 Protein denotes c-rel
T22392 10524-10527 Protein denotes p52
T22391 10379-10383 Protein denotes NFAT
T22390 10239-10241 Protein denotes c1
T22389 10232-10238 Protein denotes NFATc2
T22388 10224-10227 Protein denotes p50
T22387 10220-10223 Protein denotes p65
T20293 39932-39938 Protein denotes IL-1RA
T20292 39682-39687 Protein denotes GAPDH
T20291 39671-39677 Protein denotes IL-1RA
T20290 39489-39495 Protein denotes IL-1RA
T20289 39420-39421 Protein denotes 3
T20288 39413-39419 Protein denotes NFATP2
T20287 39360-39366 Protein denotes NFIL-6
T20286 38870-38876 Protein denotes IL-1RA
T23893 18710-18716 Protein denotes TSST-1
T23892 18679-18685 Protein denotes TSST-1
T23891 18649-18655 Protein denotes TSST-1
T23890 18589-18595 Protein denotes IL-1RA
T23889 18539-18545 Protein denotes TSST-1
T22401 10740-10742 Protein denotes c1
T22400 10731-10738 Protein denotes NFAT c2
T22399 10723-10726 Protein denotes p50
T22398 10718-10721 Protein denotes p65
T22397 10624-10626 Protein denotes c2
T22396 10616-10622 Protein denotes NFATc1
T21003 40720-40726 Protein denotes TSST-1
T21002 40707-40713 Protein denotes TSST-1
T21001 40435-40441 Protein denotes TSST-1
T21000 40422-40428 Protein denotes TSST-1
T17947 34702-34708 Protein denotes TSST-1
T17946 34454-34460 Protein denotes TSST-1
T10514 22790-22796 Protein denotes IL-1RA
T10513 22572-22578 Protein denotes IL-1RA
T10512 22460-22466 Protein denotes IL-1RA
T10511 22319-22325 Protein denotes IL-1RA
T10510 22023-22029 Protein denotes IL-1RA
T10509 22007-22013 Protein denotes IL-1RA
T10508 21974-21980 Protein denotes IL-1RA
T10507 21843-21849 Protein denotes NFIL-6
T10506 21826-21830 Protein denotes NFAT
T10505 21754-21760 Protein denotes IL-1RA
T10504 21704-21710 Protein denotes IL-1RA
T10503 21591-21597 Protein denotes IL-1RA
T299 69-73 Protein denotes IL-6
T300 119-124 Protein denotes IL-1β
T301 125-149 Protein denotes IL-1 receptor antagonist
T302 572-600 Protein denotes toxic shock syndrome toxin 1
T303 602-608 Protein denotes TSST-1
T304 668-687 Protein denotes NFinterleukin(IL)-6
T305 692-696 Protein denotes NFAT
T306 715-721 Protein denotes TSST-1
T307 764-769 Protein denotes IL-1β
T308 771-775 Protein denotes IL-6
T309 777-800 Protein denotes tumor necrosis factor α
T310 804-816 Protein denotes interferon γ
T4993 16103-16109 Protein denotes TSST-1
T4992 16001-16007 Protein denotes TGFβ 1
T4991 15991-15996 Protein denotes IL-10
T4990 15985-15989 Protein denotes IL-4
T4989 15978-15983 Protein denotes IL-12
T4988 15972-15976 Protein denotes IL-2
T4987 15948-15953 Protein denotes TGFβ1
T4986 15941-15946 Protein denotes IL-10
T4985 15935-15939 Protein denotes IL-4
T4984 15928-15933 Protein denotes IL-12
T4983 15922-15926 Protein denotes IL-2
T4982 15884-15890 Protein denotes TSST-1
T4981 15871-15877 Protein denotes TSST-1
T4980 15829-15835 Protein denotes TSST-1
T4979 15703-15707 Protein denotes IFNγ
T4978 15598-15602 Protein denotes IFNγ
T4977 15590-15594 Protein denotes IFNγ
T4976 15449-15453 Protein denotes TNFα
T4975 15392-15398 Protein denotes TSST-1
T4974 15379-15385 Protein denotes TSST-1
T12389 30158-30164 Protein denotes TSST-1
T12388 29948-29954 Protein denotes IL-1RA
T12387 29647-29653 Protein denotes IL-1RA
T12386 29634-29638 Protein denotes TNFα
T12385 29432-29438 Protein denotes IL-1RA
T12384 29349-29353 Protein denotes TNFα
T12383 29305-29311 Protein denotes TSST-1
T12382 29149-29155 Protein denotes TSST-1
T12381 29096-29102 Protein denotes TSST-1
T12380 29068-29074 Protein denotes IL-1RA
T12379 28960-28966 Protein denotes IL-1RA
T12378 28945-28951 Protein denotes TSST-1
T12377 28869-28873 Protein denotes TNFα
T12376 28820-28826 Protein denotes TSST-1
T12375 28774-28778 Protein denotes IFNγ
T12374 28766-28770 Protein denotes IL-6
T12373 28759-28764 Protein denotes IL-1β
T12372 28753-28757 Protein denotes TNFα
T12371 28722-28728 Protein denotes IL-1RA
T12370 28713-28717 Protein denotes IL-8
T12369 28660-28664 Protein denotes NFAT
T12368 28649-28655 Protein denotes NFIL-6
T12367 28617-28623 Protein denotes TSST-1
T12366 28540-28546 Protein denotes IL-1RA
T12409 31602-31607 Protein denotes IL-1β
T12408 31587-31593 Protein denotes IL-1RA
T12407 31362-31368 Protein denotes TSST-1
T12406 31346-31352 Protein denotes TSST-1
T12405 31095-31099 Protein denotes IL-2
T12404 31080-31084 Protein denotes IL-1
T12403 31064-31070 Protein denotes TSST-1
T12402 30993-30998 Protein denotes IL-1β
T12401 30919-30925 Protein denotes TSST-1
T12400 30891-30897 Protein denotes IL-1RA
T12399 30885-30890 Protein denotes IL-1β
T12398 30851-30855 Protein denotes IL-1
T12397 30805-30810 Protein denotes IL-1β
T12396 30793-30799 Protein denotes IL-1RA
T12395 30702-30708 Protein denotes TSST-1
T12394 30674-30680 Protein denotes IL-1RA
T12393 30668-30673 Protein denotes IL-1β
T12392 30552-30558 Protein denotes IL-1RA
T12391 30537-30543 Protein denotes TSST-1
T12390 30364-30370 Protein denotes TSST-1
T26188 27870-27876 Protein denotes IL-1RA
T23018 13297-13303 Protein denotes IL-1RA
T23017 13270-13276 Protein denotes TSST-1
T23016 13176-13182 Protein denotes TSST-1
T23015 13104-13110 Protein denotes IL-1RA
T23014 13054-13060 Protein denotes TSST-1
T23013 12956-12962 Protein denotes TSST-1
T23012 12943-12949 Protein denotes TSST-1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T24446 19300-19306 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T24445 18953-18959 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T24444 19648-19654 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T24443 19609-19615 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T24442 19379-19385 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T24441 19177-19183 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T24440 19160-19166 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T24439 19085-19091 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T24438 19017-19023 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T24437 18896-18902 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25078 20919-20925 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T25077 20827-20833 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T25076 21479-21484 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T25075 21220-21225 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T25074 21096-21101 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T25073 20913-20918 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T25072 20821-20826 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T23361 13297-13303 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T23360 13104-13110 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T23359 12854-12860 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T23358 12748-12754 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T23357 13270-13276 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23356 13176-13182 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23355 13054-13060 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23354 12956-12962 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23353 12943-12949 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23352 12824-12830 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23351 12786-12792 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23350 12623-12629 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23349 12536-12542 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23348 12512-12518 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23347 12398-12404 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23346 12385-12391 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23345 12267-12273 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23344 12243-12249 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23343 12652-12657 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T23342 12480-12485 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T23341 12297-12302 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T23340 12189-12194 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T22591 10524-10527 http://www.uniprot.org/uniprot/Q00653 denotes p52
T22590 10317-10337 http://www.uniprot.org/uniprot/P18848 denotes DNA binding proteins
T22589 10317-10337 http://www.uniprot.org/uniprot/P10226 denotes DNA binding proteins
T22588 10723-10726 http://www.uniprot.org/uniprot/P19838 denotes p50
T22587 10599-10602 http://www.uniprot.org/uniprot/P19838 denotes p50
T22586 10224-10227 http://www.uniprot.org/uniprot/P19838 denotes p50
T22585 10718-10721 http://www.uniprot.org/uniprot/P21579 denotes p65
T18480 34874-34878 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T18479 35417-35421 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T18478 34868-34872 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T17256 32940-32945 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T17255 32946-32952 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T17254 32654-32660 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T17253 32457-32463 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T17252 32427-32433 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T17251 32377-32383 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14314 28945-28951 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14313 28820-28826 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14312 28617-28623 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14311 28365-28371 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14310 28201-28207 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14309 27388-27394 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14308 27161-27167 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14307 27076-27082 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14306 25771-25777 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14305 31602-31607 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14304 30993-30998 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14303 30885-30890 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14302 30805-30810 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14301 30668-30673 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14300 28759-28764 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14299 28466-28471 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14298 28380-28385 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14297 25811-25816 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14296 25583-25588 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T14295 29753-29757 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14294 29634-29638 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14293 29349-29353 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14292 28869-28873 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14291 28753-28757 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14290 27512-27516 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14289 27347-27351 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14288 25574-25578 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14287 24966-24969 http://www.uniprot.org/uniprot/P19838 denotes p50
T14286 25499-25502 http://www.uniprot.org/uniprot/P21579 denotes p65
T14285 25355-25358 http://www.uniprot.org/uniprot/P21579 denotes p65
T14284 25184-25187 http://www.uniprot.org/uniprot/P21579 denotes p65
T14283 25150-25153 http://www.uniprot.org/uniprot/P21579 denotes p65
T14282 24936-24939 http://www.uniprot.org/uniprot/P21579 denotes p65
T14281 25499-25502 http://www.uniprot.org/uniprot/Q04206 denotes p65
T14280 25355-25358 http://www.uniprot.org/uniprot/Q04206 denotes p65
T14279 25184-25187 http://www.uniprot.org/uniprot/Q04206 denotes p65
T14278 25150-25153 http://www.uniprot.org/uniprot/Q04206 denotes p65
T14277 24936-24939 http://www.uniprot.org/uniprot/Q04206 denotes p65
T14276 32024-32030 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14275 30891-30897 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14274 30793-30799 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14273 30674-30680 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14272 30552-30558 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14271 29948-29954 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14270 29678-29684 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14269 29647-29653 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14268 29432-29438 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14267 29068-29074 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14266 28960-28966 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14265 28722-28728 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14244 25000-25004 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14243 24778-24782 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14242 24659-24663 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14321 30702-30708 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14320 30537-30543 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14319 30364-30370 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14318 30158-30164 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14317 29305-29311 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14316 29149-29155 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14315 29096-29102 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T10789 22790-22796 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10788 22572-22578 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10787 22460-22466 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10786 22319-22325 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10785 22023-22029 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10784 22007-22013 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10783 21974-21980 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10782 21754-21760 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10781 21704-21710 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T10780 21591-21597 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T9874 19893-19898 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T9873 19774-19779 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T9872 19690-19695 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T9871 20743-20749 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T9870 20730-20736 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T9869 20706-20712 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T9868 20332-20338 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T9867 20310-20316 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T9866 20272-20278 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T9865 19675-19681 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T9884 20663-20667 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T9883 20511-20517 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T9882 20186-20192 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T9881 20032-20038 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T9880 19899-19905 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T9879 19784-19790 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T9878 19696-19702 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T9877 20526-20531 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T9876 20180-20185 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T9875 20021-20026 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T8664 16405-16409 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T8663 16399-16403 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T8662 16620-16626 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T8661 16503-16509 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T8660 16297-16303 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T8659 18336-18342 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8658 18301-18307 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8657 17906-17912 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8656 17832-17838 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8655 17468-17474 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8654 17423-17429 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8653 17291-17297 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8652 17230-17236 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8651 17096-17102 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8650 17000-17006 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8649 16282-16288 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T8648 16249-16255 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6094 15991-15996 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T6093 15941-15946 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T6092 15985-15989 http://www.uniprot.org/uniprot/P05112 denotes IL-4
T6091 15935-15939 http://www.uniprot.org/uniprot/P05112 denotes IL-4
T6090 15978-15983 http://www.uniprot.org/uniprot/P29460 denotes IL-12
T6089 15928-15933 http://www.uniprot.org/uniprot/P29460 denotes IL-12
T6088 15978-15983 http://www.uniprot.org/uniprot/P29459 denotes IL-12
T6087 15928-15933 http://www.uniprot.org/uniprot/P29459 denotes IL-12
T6086 15972-15976 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T6085 15922-15926 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T6084 15044-15050 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6083 14924-14930 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6082 14814-14820 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6081 14725-14731 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6080 14485-14491 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6079 14400-14406 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6078 14164-14170 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6077 14143-14149 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T6076 12146-12151 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T6075 11932-11937 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T6074 11813-11818 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T6073 11704-11709 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T6072 11685-11690 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T6071 13564-13568 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T6070 13500-13504 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T6069 13436-13440 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T6068 13397-13401 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T6067 11089-11093 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T6066 10972-10976 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T6065 15035-15039 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6064 14915-14919 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6063 14805-14809 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6051 11077-11081 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T6050 10960-10964 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T6049 16160-16166 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6048 16147-16153 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6047 16103-16109 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6046 15884-15890 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6045 15871-15877 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6044 15829-15835 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6043 15392-15398 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6042 15379-15385 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6041 14700-14706 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6040 14620-14626 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6039 14539-14545 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6038 14443-14449 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6037 14096-14102 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6036 14083-14089 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6035 14059-14065 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6034 13626-13632 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6033 13613-13619 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6032 13589-13595 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6031 12121-12127 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6030 12039-12045 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6029 12001-12007 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6028 11889-11895 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6027 11671-11677 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6026 10891-10897 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6025 10861-10867 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T438 1732-1738 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T439 1851-1857 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T440 804-816 http://www.uniprot.org/uniprot/P01579 denotes interferon γ
T441 914-918 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T442 1004-1008 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T443 1162-1166 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T444 1274-1280 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T445 1567-1573 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T446 1753-1759 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T447 2102-2108 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T448 2199-2205 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T449 1896-1900 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T1917 5446-5452 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T1918 5508-5514 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T1919 5627-5633 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T1920 5822-5828 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T1921 3771-3775 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T1922 5067-5071 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T1923 5266-5270 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T1924 4917-4923 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T1925 5054-5059 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T1926 5114-5118 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T1927 5120-5124 http://www.uniprot.org/uniprot/P05112 denotes IL-4
T1928 5126-5131 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T1929 5133-5138 http://www.uniprot.org/uniprot/P29459 denotes IL-12
T1930 5133-5138 http://www.uniprot.org/uniprot/P29460 denotes IL-12
T1931 5660-5664 http://www.uniprot.org/uniprot/P17947 denotes PU.1
T3643 5916-5920 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T3644 6187-6191 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T3645 6863-6867 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T3646 5922-5926 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T3647 6263-6267 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T3648 5996-6002 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3649 6026-6032 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3650 6397-6403 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3651 6934-6940 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3652 6979-6985 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3653 7063-7069 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3654 7100-7106 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3655 7130-7136 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T3656 6223-6227 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T3657 6475-6479 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T3658 6544-6547 http://www.uniprot.org/uniprot/Q04206 denotes p65
T3659 6689-6692 http://www.uniprot.org/uniprot/Q04206 denotes p65
T3660 6544-6547 http://www.uniprot.org/uniprot/P21579 denotes p65
T3661 6689-6692 http://www.uniprot.org/uniprot/P21579 denotes p65
T3662 6574-6577 http://www.uniprot.org/uniprot/P19838 denotes p50
T3663 6718-6721 http://www.uniprot.org/uniprot/P19838 denotes p50
T3664 6731-6734 http://www.uniprot.org/uniprot/Q00653 denotes p52
T1907 3042-3046 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T1908 3473-3477 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T1909 5048-5052 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T1910 5192-5196 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T1911 3100-3105 http://www.uniprot.org/uniprot/Q99836 denotes MyD88
T1912 3467-3471 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T1913 5061-5065 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T1914 5371-5375 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T1915 3549-3555 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T1916 5076-5082 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T18481 34889-34893 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T426 69-73 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T427 771-775 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T428 1679-1683 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T429 119-124 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T430 764-769 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T431 1669-1674 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T432 1747-1752 http://www.uniprot.org/uniprot/P01584 denotes IL-1β
T433 599-606 http://www.uniprot.org/uniprot/P06886 denotes 1 (TSST
T434 715-721 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T435 1385-1391 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T436 1477-1483 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T437 1615-1621 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T6062 14158-14162 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6061 14028-14032 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6060 13936-13940 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6059 13775-13779 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6058 13731-13735 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6057 11083-11087 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6056 10966-10970 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T6055 15449-15453 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T6054 15291-15295 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T6053 15142-15146 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T6052 15121-15125 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T14256 26421-26427 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14255 26207-26213 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14254 25923-25929 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14253 25842-25848 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14252 24797-24803 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14251 24668-24674 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14250 28713-28717 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14249 27651-27655 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14248 26933-26937 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14247 25283-25287 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14246 25249-25253 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14245 25095-25099 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T14264 28540-28546 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14263 28386-28392 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14262 27682-27688 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14261 26946-26952 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14260 26822-26828 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14259 26708-26714 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14258 26543-26549 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T14257 26513-26519 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T21844 9497-9500 http://www.uniprot.org/uniprot/Q04206 denotes p65
T21843 9232-9236 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T21842 9226-9230 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T21841 9483-9487 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T21840 9375-9379 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T21839 9241-9245 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T21838 9172-9176 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T20582 39890-39895 http://www.uniprot.org/uniprot/P04406 denotes GAPDH
T20581 39682-39687 http://www.uniprot.org/uniprot/P04406 denotes GAPDH
T20580 39932-39938 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T20579 39811-39817 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T20578 39671-39677 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T20577 39489-39495 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T20576 38870-38876 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T19976 38298-38302 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T19975 38156-38160 http://www.uniprot.org/uniprot/P10145 denotes IL-8
T19974 38145-38151 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T19973 38070-38074 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T19972 38055-38059 http://www.uniprot.org/uniprot/P01375 denotes TNFα
T19367 37101-37104 http://www.uniprot.org/uniprot/P21579 denotes p65
T19366 37101-37104 http://www.uniprot.org/uniprot/Q04206 denotes p65
T19365 37073-37076 http://www.uniprot.org/uniprot/P19838 denotes p50
T19364 36967-36972 http://www.uniprot.org/uniprot/Q04864 denotes c-Rel
T19363 37127-37130 http://www.uniprot.org/uniprot/Q00653 denotes p52
T19362 36944-36947 http://www.uniprot.org/uniprot/Q00653 denotes p52
T14329 31095-31099 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T14328 28766-28770 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T14327 28476-28480 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T14326 26412-26416 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T14325 31362-31368 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14324 31346-31352 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14323 31064-31070 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T14322 30919-30925 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T22584 10604-10607 http://www.uniprot.org/uniprot/P21579 denotes p65
T22583 10220-10223 http://www.uniprot.org/uniprot/P21579 denotes p65
T22582 10718-10721 http://www.uniprot.org/uniprot/Q04206 denotes p65
T22581 10604-10607 http://www.uniprot.org/uniprot/Q04206 denotes p65
T22580 10220-10223 http://www.uniprot.org/uniprot/Q04206 denotes p65
T21853 10060-10066 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21852 9947-9953 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21851 9765-9771 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21850 9739-9745 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21849 9676-9682 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21848 9661-9667 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21847 9641-9647 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21846 9506-9509 http://www.uniprot.org/uniprot/P19838 denotes p50
T21845 9497-9500 http://www.uniprot.org/uniprot/P21579 denotes p65
T25804 22882-22888 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T25089 21300-21306 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25088 21279-21285 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25087 21266-21272 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25086 21027-21033 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25085 21014-21020 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25084 20977-20983 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25083 20879-20885 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25082 20855-20861 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T25081 21464-21470 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T25080 21226-21232 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T25079 21107-21113 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T25805 23374-23380 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T26234 27870-27876 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T25807 23429-23434 http://www.uniprot.org/uniprot/P04406 denotes GAPDH
T25806 23575-23581 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T23993 18589-18595 http://www.uniprot.org/uniprot/P18510 denotes IL-1RA
T23992 18710-18716 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23991 18679-18685 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23990 18649-18655 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T23989 18539-18545 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21171 40720-40726 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21170 40707-40713 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21169 40435-40441 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T21168 40422-40428 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T18965 36396-36399 http://www.uniprot.org/uniprot/P21579 denotes p65
T18964 36396-36399 http://www.uniprot.org/uniprot/Q04206 denotes p65
T18077 34702-34708 http://www.uniprot.org/uniprot/P06886 denotes TSST-1
T18076 34454-34460 http://www.uniprot.org/uniprot/P06886 denotes TSST-1

UBERON-AE

Id Subject Object Predicate Lexical cue
T187 446-451 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T21460 9447-9451 http://purl.obolibrary.org/obo/UBERON_0000033 denotes head
T21459 9294-9298 http://purl.obolibrary.org/obo/UBERON_0000033 denotes head
T17617 33977-33982 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17616 33453-33458 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T4718 11236-11241 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1071 4722-4727 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

GO-BP

Id Subject Object Predicate Lexical cue
T22371 10321-10347 http://purl.obolibrary.org/obo/GO_0032092 denotes binding proteins activated
T20272 39427-39430 http://purl.obolibrary.org/obo/GO_0033968 denotes GCA
T20271 38841-38854 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T20270 38779-38792 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T20269 38765-38800 http://purl.obolibrary.org/obo/GO_0032792 denotes Inhibition of transcription factors
T20268 38765-38800 http://purl.obolibrary.org/obo/GO_0043433 denotes Inhibition of transcription factors
T20267 38765-38800 http://purl.obolibrary.org/obo/GO_1901484 denotes Inhibition of transcription factors
T19201 37858-37860 http://purl.obolibrary.org/obo/GO_0033968 denotes CA
T19200 37697-37708 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T18272 35140-35143 http://purl.obolibrary.org/obo/GO_0051731 denotes PNK
T11938 31400-31421 http://purl.obolibrary.org/obo/GO_0007165 denotes pathway for signaling
T11937 31311-31329 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T11936 31215-31230 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T11935 31095-31110 http://purl.obolibrary.org/obo/GO_0032663 denotes IL-2 production
T11934 31095-31110 http://purl.obolibrary.org/obo/GO_0032623 denotes IL-2 production
T11933 30519-30529 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T11932 29380-29390 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T11931 29274-29284 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T11930 28526-28536 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T11929 28452-28462 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T11928 28320-28332 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T11927 31870-31886 http://purl.obolibrary.org/obo/GO_0033674 denotes activated kinase
T11926 27560-27576 http://purl.obolibrary.org/obo/GO_0033674 denotes activated kinase
T11925 31862-31886 http://purl.obolibrary.org/obo/GO_0004707 denotes mitogen-activated kinase
T11924 27552-27576 http://purl.obolibrary.org/obo/GO_0004707 denotes mitogen-activated kinase
T11923 27548-27551 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T11922 26735-26743 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T11921 26355-26386 http://purl.obolibrary.org/obo/GO_1901485 denotes activated transcription factors
T11920 26355-26386 http://purl.obolibrary.org/obo/GO_0032793 denotes activated transcription factors
T11919 26355-26386 http://purl.obolibrary.org/obo/GO_0051091 denotes activated transcription factors
T11918 24633-24650 http://purl.obolibrary.org/obo/GO_0034097 denotes cytokine response
T11917 24522-24530 http://purl.obolibrary.org/obo/GO_0045292 denotes splicing
T11916 30617-30630 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11915 26365-26378 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11914 25288-25301 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11913 25254-25267 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11912 25100-25113 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11911 24567-24580 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11910 24020-24033 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T11909 32142-32149 http://purl.obolibrary.org/obo/GO_0023052 denotes signals
T11908 31887-31896 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11907 31825-31834 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11906 31412-31421 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11905 31311-31320 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11904 27577-27586 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11903 27258-27267 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11902 27138-27147 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11901 23993-24002 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11900 23905-23914 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T11899 23900-23914 http://purl.obolibrary.org/obo/GO_0014065 denotes PI3K-signaling
T11898 31847-31851 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T11897 31763-31767 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T11896 31639-31643 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T10460 21929-21966 http://purl.obolibrary.org/obo/GO_0051090 denotes activity of the transcription factors
T10459 21929-21966 http://purl.obolibrary.org/obo/GO_0006352 denotes activity of the transcription factors
T10458 21929-21966 http://purl.obolibrary.org/obo/GO_0034246 denotes activity of the transcription factors
T10457 21929-21966 http://purl.obolibrary.org/obo/GO_0003700 denotes activity of the transcription factors
T10456 21929-21966 http://purl.obolibrary.org/obo/GO_0001071 denotes activity of the transcription factors
T10455 21929-21966 http://purl.obolibrary.org/obo/GO_0001070 denotes activity of the transcription factors
T10454 21929-21966 http://purl.obolibrary.org/obo/GO_0000988 denotes activity of the transcription factors
T10453 21929-21966 http://purl.obolibrary.org/obo/GO_0051091 denotes activity of the transcription factors
T10452 22729-22742 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T10451 21945-21958 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T10450 21666-21679 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T10449 21554-21567 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T10448 21540-21575 http://purl.obolibrary.org/obo/GO_0032792 denotes Inhibition of transcription factors
T10447 21929-21966 http://purl.obolibrary.org/obo/GO_0043433 denotes activity of the transcription factors
T10446 21540-21575 http://purl.obolibrary.org/obo/GO_0043433 denotes Inhibition of transcription factors
T10445 21540-21575 http://purl.obolibrary.org/obo/GO_1901484 denotes Inhibition of transcription factors
T8034 17708-17729 http://purl.obolibrary.org/obo/GO_0051098 denotes regulation of binding
T8033 17708-17718 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T8032 17705-17729 http://purl.obolibrary.org/obo/GO_1900132 denotes up-regulation of binding
T8031 17705-17729 http://purl.obolibrary.org/obo/GO_1904575 denotes up-regulation of binding
T8030 17705-17729 http://purl.obolibrary.org/obo/GO_1904528 denotes up-regulation of binding
T8029 17705-17729 http://purl.obolibrary.org/obo/GO_0043388 denotes up-regulation of binding
T8028 17705-17729 http://purl.obolibrary.org/obo/GO_0033343 denotes up-regulation of binding
T8027 17705-17729 http://purl.obolibrary.org/obo/GO_1900122 denotes up-regulation of binding
T8026 17705-17729 http://purl.obolibrary.org/obo/GO_0051099 denotes up-regulation of binding
T8025 17705-17729 http://purl.obolibrary.org/obo/GO_0032092 denotes up-regulation of binding
T8024 18029-18042 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T8023 16578-16591 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T8022 16454-16467 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T8021 16444-16475 http://purl.obolibrary.org/obo/GO_1901485 denotes activated transcription factors
T8020 16444-16475 http://purl.obolibrary.org/obo/GO_0032793 denotes activated transcription factors
T8019 16444-16475 http://purl.obolibrary.org/obo/GO_0051091 denotes activated transcription factors
T4761 13500-13515 http://purl.obolibrary.org/obo/GO_0032675 denotes IL-6 production
T4760 13564-13579 http://purl.obolibrary.org/obo/GO_0032635 denotes IL-6 production
T4759 13500-13515 http://purl.obolibrary.org/obo/GO_0032635 denotes IL-6 production
T4758 15803-15813 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T4757 11799-11809 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T4756 11428-11441 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T4755 15454-15463 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T4754 11217-11226 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T4753 11208-11226 http://purl.obolibrary.org/obo/GO_0050663 denotes cytokine secretion
T206 125-138 http://purl.obolibrary.org/obo/GO_0004908 denotes IL-1 receptor
T207 406-414 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T208 452-473 http://purl.obolibrary.org/obo/GO_0002449 denotes immune cells mediated
T209 452-473 http://purl.obolibrary.org/obo/GO_0002456 denotes immune cells mediated
T210 452-473 http://purl.obolibrary.org/obo/GO_0019724 denotes immune cells mediated
T211 452-473 http://purl.obolibrary.org/obo/GO_0002228 denotes immune cells mediated
T212 452-473 http://purl.obolibrary.org/obo/GO_0002443 denotes immune cells mediated
T213 452-473 http://purl.obolibrary.org/obo/GO_0001909 denotes immune cells mediated
T214 783-791 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T215 783-791 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T216 783-791 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T217 783-791 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T218 1630-1651 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T219 1989-2011 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T220 1882-1900 http://purl.obolibrary.org/obo/GO_0032623 denotes production of IL-2
T221 1882-1900 http://purl.obolibrary.org/obo/GO_0032663 denotes production of IL-2
T222 2048-2057 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T223 2181-2191 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T11895 31552-31556 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T11894 31395-31399 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T11893 27539-27543 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T11892 23900-23904 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T9561 19945-19957 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T26186 28017-28030 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T20995 40142-40155 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T20994 40128-40163 http://purl.obolibrary.org/obo/GO_0051090 denotes activities to transcription factors
T20993 40128-40163 http://purl.obolibrary.org/obo/GO_0006352 denotes activities to transcription factors
T20992 40128-40163 http://purl.obolibrary.org/obo/GO_0043433 denotes activities to transcription factors
T20991 40128-40163 http://purl.obolibrary.org/obo/GO_0034246 denotes activities to transcription factors
T20990 40128-40163 http://purl.obolibrary.org/obo/GO_0003700 denotes activities to transcription factors
T20989 40128-40163 http://purl.obolibrary.org/obo/GO_0001071 denotes activities to transcription factors
T20988 40128-40163 http://purl.obolibrary.org/obo/GO_0001070 denotes activities to transcription factors
T20987 40128-40163 http://purl.obolibrary.org/obo/GO_0000988 denotes activities to transcription factors
T20986 40128-40163 http://purl.obolibrary.org/obo/GO_0051091 denotes activities to transcription factors
T17943 34173-34186 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T17109 32574-32587 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T17108 32281-32294 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T4770 15958-15976 http://purl.obolibrary.org/obo/GO_0032663 denotes production of IL-2
T4769 15958-15976 http://purl.obolibrary.org/obo/GO_0032623 denotes production of IL-2
T4768 14028-14043 http://purl.obolibrary.org/obo/GO_0032637 denotes IL-8 production
T4767 13936-13951 http://purl.obolibrary.org/obo/GO_0032637 denotes IL-8 production
T4766 13775-13790 http://purl.obolibrary.org/obo/GO_0032637 denotes IL-8 production
T4765 14028-14043 http://purl.obolibrary.org/obo/GO_0032677 denotes IL-8 production
T4764 13936-13951 http://purl.obolibrary.org/obo/GO_0032677 denotes IL-8 production
T4763 13775-13790 http://purl.obolibrary.org/obo/GO_0032677 denotes IL-8 production
T4762 13564-13579 http://purl.obolibrary.org/obo/GO_0032675 denotes IL-6 production
T1092 2577-2585 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T1093 4521-4529 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T1094 3387-3390 http://purl.obolibrary.org/obo/GO_0034727 denotes PMN
T1095 3420-3429 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T1096 3771-3787 http://purl.obolibrary.org/obo/GO_0098758 denotes IL-8 in response
T1097 3771-3787 http://purl.obolibrary.org/obo/GO_0098759 denotes IL-8 in response
T1098 4163-4167 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T1099 4665-4680 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T1100 5479-5492 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T1101 4681-4691 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T1102 5016-5035 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T1103 5573-5585 http://purl.obolibrary.org/obo/GO_0032496 denotes LPS-response

GO-MF

Id Subject Object Predicate Lexical cue
T26189 28038-28045 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T25547 22867-22884 http://purl.obolibrary.org/obo/GO_0019955 denotes binding to the IL
T25546 23197-23204 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T25545 22867-22874 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T25544 22863-22874 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T22407 10321-10347 http://purl.obolibrary.org/obo/GO_0032794 denotes binding proteins activated
T22406 10321-10337 http://purl.obolibrary.org/obo/GO_0005515 denotes binding proteins
T22405 10321-10328 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T21527 9232-9236 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T21526 9483-9487 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T21525 9375-9379 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T21524 9241-9245 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T21523 9172-9176 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T21522 8976-8991 http://purl.obolibrary.org/obo/GO_0051525 denotes binding of NFAT
T21521 9899-9906 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T21520 9610-9617 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T21519 8976-8983 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T21518 9895-9906 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T21517 9606-9617 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T21516 8972-8983 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T20300 39427-39430 http://purl.obolibrary.org/obo/GO_0033968 denotes GCA
T20299 38830-38862 http://purl.obolibrary.org/obo/GO_0070491 denotes binding of transcription factors
T20298 38830-38862 http://purl.obolibrary.org/obo/GO_0043425 denotes binding of transcription factors
T20297 38830-38862 http://purl.obolibrary.org/obo/GO_0033613 denotes binding of transcription factors
T19773 38298-38302 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T19772 38156-38160 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T19771 38070-38074 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T19770 38342-38346 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T19769 38061-38065 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T19240 37858-37860 http://purl.obolibrary.org/obo/GO_0033968 denotes CA
T19239 37697-37708 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T19238 37730-37738 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T19237 37611-37621 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T19236 37308-37318 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T19235 37040-37050 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T19234 36839-36849 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T19233 36644-36660 http://purl.obolibrary.org/obo/GO_0005515 denotes binding proteins
T19232 36644-36651 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T19231 36640-36651 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T17126 32595-32602 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T17125 32302-32309 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12572 32069-32085 http://purl.obolibrary.org/obo/GO_0005515 denotes binding proteins
T12571 31095-31099 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T12570 31080-31084 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T12569 30851-30855 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T12568 27548-27551 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T12567 28766-28770 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T12566 28476-28480 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T12565 26412-26416 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T12564 26355-26386 http://purl.obolibrary.org/obo/GO_0033613 denotes activated transcription factors
T12563 32065-32076 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA-binding
T12562 26261-26272 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T12561 28713-28717 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12560 27651-27655 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12559 26933-26937 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12558 25283-25287 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12557 25249-25253 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12556 25095-25099 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12555 25000-25004 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12554 24778-24782 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12553 24659-24663 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T12552 24383-24395 http://purl.obolibrary.org/obo/GO_0051525 denotes NFAT binding
T12551 24247-24262 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucans
T12550 25394-25411 http://purl.obolibrary.org/obo/GO_0019955 denotes binding to the IL
T12549 24041-24061 http://purl.obolibrary.org/obo/GO_0019955 denotes binding and cytokine
T12548 32069-32076 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12547 30379-30386 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12546 30173-30180 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12545 29814-29821 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12544 29608-29615 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12543 29325-29332 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12542 29164-29171 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T9622 20663-20667 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T9621 20637-20641 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T5021 15991-15996 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T5020 15941-15946 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T5019 15985-15989 http://purl.obolibrary.org/obo/GO_0005136 denotes IL-4
T5018 15935-15939 http://purl.obolibrary.org/obo/GO_0005136 denotes IL-4
T5017 15978-15983 http://purl.obolibrary.org/obo/GO_0005143 denotes IL-12
T5016 15928-15933 http://purl.obolibrary.org/obo/GO_0005143 denotes IL-12
T5015 15972-15976 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T5014 15922-15926 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T5013 11598-11612 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T5012 11449-11456 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T5011 13564-13568 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T5010 13500-13504 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T5009 13436-13440 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T5008 13397-13401 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T5007 11089-11093 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T5006 10972-10976 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T5005 15035-15039 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T5004 14915-14919 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T5003 14805-14809 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T5002 14158-14162 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T5001 14028-14032 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T5000 13936-13940 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T4999 13775-13779 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T4998 13731-13735 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T335 27-38 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T336 1492-1503 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T337 31-38 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T338 961-968 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T339 1212-1219 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T340 1496-1503 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T341 2036-2043 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T342 69-73 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T343 771-775 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T344 1679-1683 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T345 125-129 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T346 1867-1871 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T347 125-138 http://purl.obolibrary.org/obo/GO_0004908 denotes IL-1 receptor
T348 486-500 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T349 2240-2254 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T350 804-816 http://purl.obolibrary.org/obo/GO_0005133 denotes interferon γ
T351 914-918 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T352 1004-1008 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T353 1162-1166 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T354 1896-1900 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T355 2027-2043 http://purl.obolibrary.org/obo/GO_0005102 denotes receptor binding
T3265 5849-5856 http://purl.obolibrary.org/obo/GO_0005488 denotes Binding
T3266 6068-6075 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T3267 6528-6535 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T3268 6673-6680 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T3269 6836-6843 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T21009 40128-40163 http://purl.obolibrary.org/obo/GO_0034246 denotes activities to transcription factors
T21008 40128-40163 http://purl.obolibrary.org/obo/GO_0003700 denotes activities to transcription factors
T21007 40128-40163 http://purl.obolibrary.org/obo/GO_0001071 denotes activities to transcription factors
T21006 40128-40163 http://purl.obolibrary.org/obo/GO_0001070 denotes activities to transcription factors
T21005 40128-40163 http://purl.obolibrary.org/obo/GO_0000988 denotes activities to transcription factors
T21004 40120-40127 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8120 17497-17504 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8119 17131-17138 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8118 16981-16988 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8117 16845-16852 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8116 16599-16606 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8115 16232-16239 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8114 16227-16239 http://purl.obolibrary.org/obo/GO_0051525 denotes NFAT binding
T20296 38830-38862 http://purl.obolibrary.org/obo/GO_0008134 denotes binding of transcription factors
T20295 39464-39471 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T20294 38830-38837 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T10523 21929-21966 http://purl.obolibrary.org/obo/GO_0034246 denotes activity of the transcription factors
T10522 21929-21966 http://purl.obolibrary.org/obo/GO_0003700 denotes activity of the transcription factors
T10521 21929-21966 http://purl.obolibrary.org/obo/GO_0001071 denotes activity of the transcription factors
T10520 21929-21966 http://purl.obolibrary.org/obo/GO_0001070 denotes activity of the transcription factors
T10519 21929-21966 http://purl.obolibrary.org/obo/GO_0000988 denotes activity of the transcription factors
T10518 22704-22711 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T10517 22254-22261 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T10516 22091-22098 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T10515 21921-21928 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8132 16578-16606 http://purl.obolibrary.org/obo/GO_0070491 denotes transcription factor binding
T8131 16578-16606 http://purl.obolibrary.org/obo/GO_0043425 denotes transcription factor binding
T8130 16578-16606 http://purl.obolibrary.org/obo/GO_0008134 denotes transcription factor binding
T8129 16578-16606 http://purl.obolibrary.org/obo/GO_0033613 denotes transcription factor binding
T8128 16444-16475 http://purl.obolibrary.org/obo/GO_0033613 denotes activated transcription factors
T8127 16405-16409 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T8126 16232-16246 http://purl.obolibrary.org/obo/GO_0001530 denotes binding in LPS
T8125 18222-18229 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8124 18121-18128 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8123 17974-17981 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8122 17860-17867 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8121 17722-17729 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12541 29120-29127 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12540 28835-28842 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12539 28632-28639 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12538 27408-27415 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12537 26489-26496 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12536 26315-26322 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12535 26265-26272 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12534 25968-25975 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12533 25637-25644 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12532 25503-25510 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12531 25394-25401 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12530 24920-24927 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12529 24588-24595 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12528 24388-24395 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12527 24271-24278 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12526 24041-24048 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12525 31847-31851 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T12524 31763-31767 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T12523 31639-31643 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T12522 31552-31556 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T12521 31395-31399 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T12520 27539-27543 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T12519 23900-23904 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T24238 19264-19271 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T24237 18915-18922 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T24236 19260-19271 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T24235 18911-18922 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T22404 10274-10281 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T22403 10317-10328 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T22402 10270-10281 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T18295 35517-35532 http://purl.obolibrary.org/obo/GO_0051525 denotes binding of NFAT
T18294 35517-35524 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T18293 35241-35248 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T18292 35140-35143 http://purl.obolibrary.org/obo/GO_0051731 denotes PNK
T18291 34889-34893 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18290 34874-34878 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T3270 6954-6961 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T3271 7201-7208 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T3272 7348-7355 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T3273 5922-5926 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T3274 6263-6267 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T3275 6223-6227 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T3276 6475-6479 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T3277 7348-7365 http://purl.obolibrary.org/obo/GO_0051525 denotes binding of NFATc2
T1187 2640-2654 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1188 2835-2849 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1189 3134-3148 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1190 3642-3656 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1191 3823-3837 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1192 3998-4012 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1193 4287-4301 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1194 4396-4410 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1195 4784-4798 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucan
T1196 2985-3003 http://purl.obolibrary.org/obo/GO_0001872 denotes binding of zymosan
T1197 2779-2807 http://purl.obolibrary.org/obo/GO_0038187 denotes pattern recognition receptor
T1198 2985-2992 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T1199 5468-5475 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T1200 5800-5807 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T1201 3461-3465 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T1202 3565-3569 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T1203 3467-3471 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T1204 5061-5065 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T4997 11083-11087 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T4996 10966-10970 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T23897 18825-18836 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T23896 18606-18626 http://purl.obolibrary.org/obo/GO_0035326 denotes Binding was enhanced
T23895 18829-18836 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T23894 18554-18561 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T17466 33372-33387 http://purl.obolibrary.org/obo/GO_0001872 denotes β-1→3-D-glucans
T1205 5371-5375 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T1206 3771-3775 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T1207 5067-5071 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T1208 5266-5270 http://purl.obolibrary.org/obo/GO_0005153 denotes IL-8
T1209 4163-4167 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T1210 5114-5118 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T1211 5120-5124 http://purl.obolibrary.org/obo/GO_0005136 denotes IL-4
T1212 5126-5131 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T1213 5133-5138 http://purl.obolibrary.org/obo/GO_0005143 denotes IL-12
T1214 5468-5500 http://purl.obolibrary.org/obo/GO_0008134 denotes binding of transcription factors
T1215 5468-5500 http://purl.obolibrary.org/obo/GO_0033613 denotes binding of transcription factors
T1216 5468-5500 http://purl.obolibrary.org/obo/GO_0043425 denotes binding of transcription factors
T1217 5468-5500 http://purl.obolibrary.org/obo/GO_0070491 denotes binding of transcription factors
T1218 5617-5629 http://purl.obolibrary.org/obo/GO_0005135 denotes 3) in the IL
T18805 36403-36411 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T18804 36587-36594 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T18803 36344-36351 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T18802 36201-36208 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T18801 36125-36132 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

GO-CC

Id Subject Object Predicate Lexical cue
T22408 10575-10580 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T19774 37907-37911 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T19253 37479-37487 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T19252 37283-37287 http://purl.obolibrary.org/obo/GO_0071735 denotes IgG1
T19251 37165-37169 http://purl.obolibrary.org/obo/GO_0071735 denotes IgG1
T19250 37730-37738 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T356 459-464 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12576 31996-32009 http://purl.obolibrary.org/obo/GO_0009274 denotes peptidoglycan
T12575 31708-31713 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12574 31126-31131 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12573 27459-27463 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T357 1129-1134 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1219 2328-2332 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1220 3219-3223 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1221 3328-3332 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1222 3757-3762 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1223 4740-4745 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1224 2328-2338 http://purl.obolibrary.org/obo/GO_0005618 denotes cell walls
T19249 37611-37621 http://purl.obolibrary.org/obo/GO_0042571 denotes antibodies
T19248 37308-37318 http://purl.obolibrary.org/obo/GO_0042571 denotes antibodies
T19247 37040-37050 http://purl.obolibrary.org/obo/GO_0042571 denotes antibodies
T19246 36839-36849 http://purl.obolibrary.org/obo/GO_0042571 denotes antibodies
T19245 37730-37738 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T19244 37611-37621 http://purl.obolibrary.org/obo/GO_0019815 denotes antibodies
T19243 37308-37318 http://purl.obolibrary.org/obo/GO_0019815 denotes antibodies
T19242 37040-37050 http://purl.obolibrary.org/obo/GO_0019815 denotes antibodies
T19241 36839-36849 http://purl.obolibrary.org/obo/GO_0019815 denotes antibodies
T18807 36403-36411 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T18806 36403-36411 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T17950 34520-34525 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T17949 34448-34453 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T17948 34419-34424 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T17623 33837-33842 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T17622 33761-33766 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9623 20685-20690 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5022 11242-11247 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T188 0-155 Sentence denotes β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio
T189 166-176 Sentence denotes Background
T190 177-287 Sentence denotes β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses.
T191 288-610 Sentence denotes Employing a comprehensive methodological approach, the aim of our in vitro study was to elucidate novel molecular and cellular mechanisms of human peripheral blood immune cells mediated by a fungal β-1→3-D-glucan, i.e. glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1).
T192 612-619 Sentence denotes Results
T193 620-845 Sentence denotes Despite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate.
T194 846-933 Sentence denotes Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h:
T195 934-1018 Sentence denotes 5000 pg/ml), likely due to binding of NFκB to a consensus site in the IL-8 promoter.
T196 1019-1087 Sentence denotes An increase in IL-1receptor antagonist(RA) production (peak at 24 h:
T197 1088-1174 Sentence denotes 12000 pg/ml) by glucan phosphate-treated cells positively correlated with IL-8 levels.
T198 1175-1337 Sentence denotes Glucan phosphate induced significant binding to a known NFIL-6 site and a new NFAT site within the IL-1RA promoter, which was confirmed by inhibition experiments.
T199 1338-1574 Sentence denotes When applied in combination with either LPS or TSST-1 at the same time points, we detected that glucan phosphate elevated the LPS- and the TSST-1-induced DNA binding of NFκB, NFIL-6 and NFAT, leading to a synergistic increase of IL-1RA.
T200 1575-1684 Sentence denotes Further, glucan phosphate modulated the TSST-1-induced inflammatory response via reduction of IL-1β and IL-6.
T201 1685-1805 Sentence denotes As a consequence, glucan phosphate shifted the TSST-1-induced IL-1β/IL-1RA ratio towards an anti-inflammatory phenotype.
T202 1806-1901 Sentence denotes Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2.
T203 1903-1913 Sentence denotes Conclusion
T204 1914-2127 Sentence denotes Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction.
T205 2128-2255 Sentence denotes Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan.
T26185 27887-28065 Sentence denotes Relative locations of previously (LRE-1) [30-33] and newly described (boxed), positively (black) and negatively (gray) regulatory transcription factor binding sites are depicted.
T26184 27835-27886 Sentence denotes Cartoon of the sense strand of the IL-1RA promoter.
T25506 23689-23726 Sentence denotes Data are shown as mean ± SEM (n = 3).
T25505 23496-23688 Sentence denotes C, Inhibition of NFκB, NFAT and NFIL-6 significantly reduced the production of IL-1RA by human PBMC following treatment with CHX, CAPE or CyA when compared to GP (* = p < 0.05; ** = p < 0.01).
T25504 23429-23495 Sentence denotes GAPDH is used as housekeeping control (representative gel, n = 4).
T25503 23313-23428 Sentence denotes B, Inhibition of NFκB, NFAT and NFIL-6 resulted in decreased IL-1RA mRNA following CHX, CAPE or CyA compared to GP.
T25502 23275-23312 Sentence denotes Data are shown as mean ± SEM (n = 4).
T25501 22899-23274 Sentence denotes A, A representative autoradiogram (lane 1: control, lane 2: GP, lane 3: GP + unlabeled mutated NFATP2/3 oligo, lane 4: GP + CAPE, lane 5: GP + CyA, lane 6: GP + CHX, lane 7: GP + unlabeled NFATP2/3 oligo, lane 8: water) as well as a graphical summary for the NFATP2/3 site, depicting a decrease in binding following inhibition when compared to GP is displayed (* = p < 0.05).
T25500 22816-22898 Sentence denotes Inhibition of GP-induced NFκB, NFAT and NFIL-6 DNA binding to the IL-1RA promoter.
T24824 21501-21538 Sentence denotes Data are shown as mean ± SEM (n = 3).
T24823 21250-21500 Sentence denotes With respect to TSST-1 or GP/TSST-1 calc. vs GP + TSST-1 we observed a pronounced anti-inflammatory action of GP, as demonstrated by an about 10–100 fold reduced ratio at 18 h and 24 h, i.e. a higher production of IL-1RA than of IL-1β (* = p < 0.05).
T24822 21126-21249 Sentence denotes When comparing LPS or GP/LPS calc. vs GP + LPS we did not find significant alterations in the IL-1β/IL-1RA ratio over 48 h.
T24821 21040-21125 Sentence denotes LPS and GP + LPS treatments resulted in generating more IL-1β than IL-1RA up to 24 h.
T24820 20887-21039 Sentence denotes Time course (48 h) of the IL-1β/IL-1RA ratio following incubation of human PBMC with LPS, TSST-1, GP + LPS, GP/LPS calc., GP + TSST-1 or GP/TSST-1 calc.
T24819 20811-20886 Sentence denotes Decreased IL-1β/IL-1RA ratio following GP + TSST-1 when compared to TSST-1.
T24201 19460-19656 Sentence denotes An autoradiogram of a representative experiment is shown in the lower panel (lane 1: water; lane 2: medium control; lane 3: GP; lane 4: LPS; lane 5: TSST-1, lane 6: GP + LPS; lane 7: GP + TSST-1).
T24200 19403-19459 Sentence denotes Medium control levels were set equal to 1 ± SEM (n = 6).
T24199 19317-19402 Sentence denotes Bars depicting the theoretical values for GP/LPS calc. and GP/TSST-1 calc. are added.
T24198 19108-19316 Sentence denotes Human PBMC were incubated with medium control, LPS, TSST-1, GP, GP + TSST-1 and GP + LPS for 1 h at 37°C. Schematic representation of the elevated NFAT-DNA binding activity to the site in the IL-1RA promoter.
T24197 18970-19107 Sentence denotes Binding was up-regulated for GP + LPS and GP + TSST-1, when compared to GP and, in the latter case, to both GP and TSST-1 (* = p < 0.05).
T24196 18883-18969 Sentence denotes GP modulated TSST-1-induced DNA binding to a new NFATP2/3 site in the IL-1RA promoter.
T23879 18825-18872 Sentence denotes DNA binding was assessed by EMSA (see methods).
T23878 18768-18824 Sentence denotes Medium control levels were set equal to 1 ± SEM (n = 6).
T23877 18606-18767 Sentence denotes Binding was enhanced for GP + LPS and GP + TSST-1, when compared to LPS, TSST-1, GP, GP/LPS calc. or GP/TSST-1 calc., respectively (* = p < 0.05; ** = p < 0.01).
T23876 18517-18605 Sentence denotes GP modulated LPS- and TSST-1-induced binding to a new NFκB3 site in the IL-1RA promoter.
T22966 13297-13390 Sentence denotes IL-1RA levels in the supernatnant were obtained by Elisa and are shown as mean ± SEM (n = 3).
T22965 13206-13296 Sentence denotes Graphs depicting the theoretical values for GP/LPS calc. and GP/TSST-1 calc. are included.
T22964 12989-13205 Sentence denotes Between 18 h and 48 h a simultaneous treatment of PBMC with GP + TSST-1 led to a synergistic effect, i.e. a higher IL-1RA production when compared to an addition of the single values for TSST-1 and GP (* = p < 0.05).
T22963 12832-12988 Sentence denotes Time course (48 h) of IL-1RA production (pg/ml) by human PBMC incubated with medium control, 100 μg GP, 250 ng TSST-1, GP + TSST-1, 250 ng LPS and GP + LPS.
T22962 12745-12831 Sentence denotes B, IL-1RA was exaggerated following GP + TSST-1 (12 h – 48 h) when compared to TSST-1.
T22961 12652-12744 Sentence denotes IL-1β levels in the supernatnant were obtained by Elisa and are shown as mean ± SEM (n = 3).
T22960 12559-12651 Sentence denotes Graphs depicting the theoretical values for GP/LPS calc. and GP/TSST-1 calc. are also shown.
T22959 12431-12558 Sentence denotes At 18 h and 24 h there was a marked reduction in IL-1β production following GP + TSST-1 when compared to TSST-1 (* = p < 0.05).
T22958 12275-12430 Sentence denotes Time course (48 h) of IL-1β production (pg/ml) by human PBMC incubated with medium control, 100 μg GP, 250 ng TSST-1, GP + TSST-1, 250 ng LPS and GP + LPS.
T22957 12186-12274 Sentence denotes A, IL-1β was down-regulated (12 h – 24 h) following GP + TSST-1 when compared to TSST-1.
T22370 10420-10780 Sentence denotes A representative dot blot showing staining of negative and positive controls (recombinant proteins NFκB p52, c-rel; nuclear extracts of PMA-treated Jurkat cells positive for NFκB p50, p65 and for NFATc1, c2) in the upper panel and staining of nuclear extracts of GP-treated PBMC (positive for NFκB p65, p50 and NFAT c2, c1) in the lower panel is shown (n = 3).
T22369 10283-10419 Sentence denotes In order to determine whether the DNA binding proteins activated by GP were related to NFκB and NFAT, an immuno(dot) blot was performed.
T22368 10215-10282 Sentence denotes NFκB p65/p50 and NFATc2/c1 were involved in GP-induced DNA binding.
T20985 40550-40917 Sentence denotes Significances of differences between experimental data (for example GP vs LPS) as well as between experimental data and theoretical values (for example GP + TSST-1 vs GP/TSST-1 calc.) were analysed using the Student's t-test (normal distribution) or the Wilcoxon Signed-Rank test (non-normal distribution), (SPSS for Windows; SPSS Science Software, Erkrath, Germany).
T20984 40352-40549 Sentence denotes To compare experimental data to a theoretical value (for example GP + TSST-1 vs GP/TSST-1 calc.) we calculated the sum of the individual effects and added these values into Fig. 1B, 3, 4, 5, and 6.
T20983 40191-40351 Sentence denotes Correlation coefficients and corresponding significances were analyzed by the Pearson test (normal distribution) or the Spearman test (non-normal distribution).
T20982 40041-40190 Sentence denotes The Kolmogorow-Smirnov test was used to evaluate, whether cytokine amounts and binding activities to transcription factors were normally distributed.
T20981 40020-40040 Sentence denotes Statistical analysis
T21469 10075-10204 Sentence denotes Medium control levels were set equal to 1± SEM and significances (* = p < 0.05) are shown with respect to medium control (n = 4).
T21468 9862-10074 Sentence denotes Schematic representation of NFκB-DNA binding activity following GP (1 and 100 μg) or TSST-1 treatment (250 ng) as well as simultaneous administration of both compounds and the theoretical value (GP/TSST-1 calc.).
T21467 9687-9861 Sentence denotes Human PBMC were incubated with medium control, LPS, TSST-1, GP (100 μg), GP + TSST-1 and GP + LPS for 1 h at 37°C. An autoradiogram from a representative experiment is shown.
T21466 9593-9686 Sentence denotes B, Decreased DNA binding of NFκB following GP + TSST-1, compared to TSST-1, GP, or TSST-1/GP.
T21465 9525-9592 Sentence denotes An autoradiogram from a representative experiment is shown (n = 7).
T21464 9427-9524 Sentence denotes Arrow with the open head indicates a supershift of NFκB-IL-8-DNA-anti-p65 and -p50, respectively.
T21463 9272-9426 Sentence denotes Arrows with the black head indicate migrational location of the NFAT-DNA, NFκB-DNA, NFIL-6-DNA or NFκB-IL-8-DNA complex compared to free probe (no shift).
T21462 9010-9271 Sentence denotes Human PBMC were incubated with medium control or GP (1 and 100 μg) for 1 h at 37°C. Nuclear extracts were incubated with a 32P-labeled NFAT, NFκB, NFIL-6 or NFκB-IL-8 oligonucleotide probe corresponding to the IFNγ, TNFα, IL-6 and IL-8 gene promoters (Table 1).
T21461 8959-9009 Sentence denotes A, GP led to DNA binding of NFAT, NFκB and NFIL-6.
T20266 39932-40018 Sentence denotes IL-1RA protein was measured in the supernatant by ELISA after 24 h incubation with GP.
T20265 39506-39931 Sentence denotes PBMC RNA was isolated with an RNeasy kit (Qiagen, Germany) and messenger RNA was transcribed into cDNA with Reactin Ready First Strand kit (Biomol) and analysed for IL-1RA and GAPDH transcripts by PCR with a HotStart "sweet" PCR mastermix (Biomol) (95°C, 30 sec, 55°C, 30 sec, 72°C, 30 sec, 25 cycles for IL-1RA and 94°C for 30 sec, 50°C for 30 sec and 72°C for 45 sec, 25 cycles for GAPDH) following 18 h incubation with GP.
T20264 39253-39505 Sentence denotes Band shifts were determined after 1 h incubation with GP as described before, including mutated oligos for NFIL-6 (TTA CAA CAG TGG ATT GCG ACA CTT AGT GGG) and NFATP2/3 (GGC GCA GAA AAG GTA AAA TAT TTA CTA TCT) binding sites within the IL-1RA promoter.
T20263 39002-39252 Sentence denotes 50 μg/ml of CAPE (caffeic-3,4-dihydroxycinnamic-acid-phenyl-ester), (Biomol, Hamburg, Germany); 400 ng/ml cyclosporin A (Calbiochem-Merck Biosciences, Bad Soden, Germany); 10 μg/ml cycloheximide (Santa Cruz Biotechnology) prior to incubation with GP.
T20262 38801-39001 Sentence denotes To inhibit translocation and binding of transcription factors to the IL-1RA promoter, PBMC were incubated for 1 h with each of the following substances (concentrations were based upon 50% inhibition):
T20261 38765-38800 Sentence denotes Inhibition of transcription factors
T19750 38648-38763 Sentence denotes Only stimulation of PBMC observed in donors showing no spontaneous cytokine release was included in the statistics.
T19749 38582-38647 Sentence denotes Cytokine amounts were all within the range of the standard curve.
T19748 38458-38581 Sentence denotes All cytokines were quantified using an ELISA plate reader (Anthos Labotec, Salzburg, Austria or Microplate Reader, BioRad).
T19747 38386-38457 Sentence denotes Samples were diluted in the same buffer as that used for the standards.
T19746 38280-38385 Sentence denotes Quantification of IL-2 as an indicator for the bioactivity of IL-1 was done as previously described [46].
T19745 38049-38279 Sentence denotes IFNγ, TNFα, IL-1 and IL-6 were determined using an ELISA from Bender Systems (Vienna, Austria), IL-1RA and IL-8 by an ELISA from R&D Systems (Wiesbaden-Nordenstadt, Germany), and TGFβ 1 using an ELISA as previously described [57].
T19744 37891-38048 Sentence denotes Supernatants of cell cultures were harvested 3, 6, 9, 12, 18, 24, 30, 36 and 48 hours after stimulation and stored at -80 °C until used and thawed only once.
T19743 37869-37890 Sentence denotes Cytokine measurements
T19199 37762-37867 Sentence denotes The blot was developed using the Vectastain® staining kit (Vector Laboratories Inc. Burlingame, CA, USA).
T19198 37499-37761 Sentence denotes After blocking with PBS/3% BSA (Fluka, Deisenhofen, Germany), the blot was incubated overnight with the primary antibodies diluted 1:2000 in PBS/1% BSA, washed again and incubated with the alkaline phosphatase-conjugated secondary antibody (1:500 in PBS/1% BSA).
T19197 37423-37498 Sentence denotes The nuclear proteins were blotted onto a nitrocellulose membrane (Bio-Rad).
T19196 36615-37422 Sentence denotes To determine whether the DNA binding proteins were related to NFκB and NFAT, dot blots using a SRC96D SNS minifold I dot blotter (Schleicher & Schüll, Dassel, Germany) were performed with the following positive controls and antibodies (all from Santa Cruz Biotechnology, Heidelberg, Germany): positive controls (10 ng/dot): NFκB p52 (80 kD) sc-4095WB, c-Rel (61 kD) sc-4030WB; Jurkat nuclear extract, PMA-stimulated; primary antibodies (1 μg/dot): anti-NFκB p50 (NLS) sc-114, anti-NFκB p65 (A) sc-109, anti-NFκB p52 (447) sc-848, a rabbit polyclonal IgG1 antiserum, anti-c-rel (N466) sc-272, anti-NFATc2 (M-20) sc-1151, anti-NFATc1 (K-18) sc-1149, two goat polyclonal IgG1 antisera; secondary antibodies (0.8 μg/dot): goat anti-rabbit IgG AP-conjugate sc-2007, and donkey anti-goat IgG AP-conjugate sc-2022.
T19195 36597-36614 Sentence denotes Immuno (Dot) blot
T18794 36445-36595 Sentence denotes To exclude non-specific reactions, a 30-fold molar excess of Oct-1 DNA (unrelated DNA, Table 1) was used, which did not compete with specific binding.
T18793 36325-36444 Sentence denotes For specificity of binding, supershift assays for NFκB with a combined p65/50 antibody were performed (data not shown).
T18792 36230-36324 Sentence denotes For such experiments, an excess (5–50×) of unlabeled oligos was added to the nuclear extracts.
T18791 36034-36229 Sentence denotes Competition experiments with labeled and unlabeled mutated oligos of the cytokine promoter binding sites (see above) were carried out in order to prevent non-specific binding to nuclear proteins.
T18790 35953-36033 Sentence denotes The intensity of shifted bands was normalized to bands of unstimulated controls.
T18789 35802-35952 Sentence denotes Nuclear extracts of purified PBMCs were prepared according to a technique described by Trede et al. [27] and modified for our experimental setup [56].
T18788 35721-35801 Sentence denotes Preparation of nuclear extracts and electrophoretic mobility shift assays (EMSA)
T17942 34605-34745 Sentence denotes In costimulatory experiments, PBMC were supplemented simultaneously with a combination of GP and TSST-1 or with a combination of GP and LPS.
T17941 34326-34604 Sentence denotes Cultures were stimulated for 1 h (EMSA) or from 0 h to 48 h (ELISA) with 1 or 100 μg per 106 cells of GP, with 250 ng/106 cells TSST-1 (Toxin Technologies, Sarasota, FL, USA) or with 250 ng/106 cells wild-type LPS from Escherichia coli serotype 0111:B4 (Sigma, Munich, Germany).
T18271 35566-35719 Sentence denotes Afterwards, the ds oligos were purified via gel filtration using Probe Quant G-50 Micro Columns (Pharmacia) according to the manufacturer's instructions.
T18270 35327-35565 Sentence denotes Mutations in the P2 site of the IFNγ promoter [29] and in the κ consensus sequence of the TNFα promoter [55] have been reported to interfere with sequences, which seem to be crucial for the binding of NFAT and NFκB proteins, respectively.
T18269 35229-35326 Sentence denotes To test the binding specificity of the oligos, mutated oligos were used as an additional control.
T18268 34794-35228 Sentence denotes The complementary double-stranded (ds) oligonucleotides (oligos) from the TNFα, IL-8, IFNγ and IL-6 promoters were synthesised from single stranded (ss) oligos (illustrated in Table 1), (TIB Molbiol, Berlin, Germany) and 32P-labeled with 5'γ-P-ATP (3,000 Ci/mmol, Amersham, Braunschweig, Germany) using the Ready-To-Go-Polynucleotide-Kinase Kit (PNK Kit, Pharmacia LKB, Freiburg, Germany) according to the manufacturer's instructions.
T18267 34747-34793 Sentence denotes Oligonucleotides (Oligos) and 5'-32-P-Labeling
T17620 33685-34131 Sentence denotes Following isolation, PBMC were cultured at a final concentration of 3 × 106 cells/ml (for ELISA measurements) or 5 × 106/ml (for gel shifts) or 1 × 106 cells/ml (for flow cytometry) in RPMI 1640 medium (BioWhittaker, Heidelberg, Germany, LPS-free), containing 10% heat-inactivated fetal calf serum (FCS, low-LPS, Invitrogen, Karlsruhe, Germany), 1% penicillin (10000 U/ml), 1% streptomycin (10000 μg/ml), and 1% 200 mM L-glutamine (BioWhittaker).
T17619 33414-33684 Sentence denotes Buffy coats were obtained from healthy blood donors in compliance with the Helsinki declaration and with the approval of the ethics committee of the University of Luebeck. The buffy coats were separated over a Ficoll-Hypaque (Biochrom, Berlin, Germany) gradient [54,55].
T17618 33390-33413 Sentence denotes Isolation of human PBMC
T11891 31899-32193 Sentence denotes This idea may be supported by another study showing that despite the use of similar PRR, LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins and acted synergistically in combination, suggestive of signals which are not equivalent in all parts [51].
T11890 31720-31898 Sentence denotes Activation of NFκB can also take place via PI3K [50], which may offer an explanation for a difference in signaling between GP (PI3K) and LPS (mitogen-activated kinase signaling).
T11889 31625-31719 Sentence denotes Signaling via PI3K has been reported to be involved in the activation of NFAT in T cells [49].
T11888 31485-31624 Sentence denotes It has been demonstrated that in septic/LPS-adapted leukocytes the PI3K pathway selectively controls sIL-1RA but not IL-1β production [48].
T11887 31362-31484 Sentence denotes TSST-1 has been shown to use the PI3K pathway for signaling [44] and this effect may be sustained by GP treatment [22,37].
T11886 31160-31361 Sentence denotes The weaker modulating effects of GP on the LPS-induced immune response observed in this study, may be attributed to delicately balanced differences in signaling pathways between LPS and TSST-1 [43-45].
T11885 31041-31159 Sentence denotes Indeed, GP reduced the TSST-1-induced, IL-1-dependent IL-2 production of murine EL-4 cells (data not shown in detail).
T11884 30865-31040 Sentence denotes Since, in fact, the IL-1β/IL-1RA ratio following GP + TSST-1 is partially less than 0.01, it is not unreasonable to assume that IL-1β bioactivity is inactivated in our system.
T11883 30719-30864 Sentence denotes In this context, it has been postulated that in vitro a 100fold excess of IL-1RA over IL-1β might control the biological effects of IL-1 [46,47].
T11882 30571-30718 Sentence denotes We think that this GP-modulated activation of transcription was reflected by the decrease of the IL-1β/IL-1RA ratio following GP + TSST-1 (Fig. 6).
T11881 30335-30570 Sentence denotes The GP-modulated increase in TSST-1-induced binding to the new NFκB3 and NFκB consensus site, the NFIL-6 site [32] as well as to the novel NFATP2/3 site may explain the synergistic up-regulation of the TSST-1-induced IL-1RA production.
T11880 30216-30334 Sentence denotes In our opinion, this site may therefore represent at least a part of the previoulsy described inhibitory element [30].
T11879 29997-30215 Sentence denotes On the other side, we found an inhibitory NFκB2/3 site (-288 and -302) towards the end of the inhibitory element, demonstrating down-regulations of the LPS- and TSST-1-induced binding, which could not be altered by GP.
T11878 29831-29996 Sentence denotes Despite the location of the new NFκB consensus site (-266 and -280) in the inhibitory element (-250 and -294) of the IL-1RA promoter [30], we observed no inhibition.
T11877 29449-29830 Sentence denotes These seemingly contradictory data could be explained by differences in either NFκB subunits or conserved nucleotides (#1, 2, 3, 10) within the decameric NFκB binding motif between the TNFα and the IL-1RA promoter (for NFκB3 the IL-1RA motif contains a T on position 10 instead of the conserved C in the TNFα motif, see Table 1), probably leading to differences in binding [41,42].
T11876 29233-29448 Sentence denotes So, while we observed a GP-mediated down-regulation of the LPS- and the TSST-1-induced NFκB binding to sites of the TNFα promoter, there was an up-regulation to NFκB3 and NFκB consensus sites of the IL-1RA promoter.
T11875 29027-29232 Sentence denotes Of the four examined NFκB sites from the IL-1RA promoter, mostly the TSST-1- and LPS-induced binding to the NFκB3 and the TSST-1-induced binding to the new NFκB consensus site seemed to be increased by GP.
T11874 28789-29026 Sentence denotes Accordingly, we found that the TSST-1-induced binding of NFκB to sites from the TNFα promoter negatively correlated with the GP-mediated enhancement of the TSST-1-induced IL-1RA production (r = -0.88; p < 0.01; data not shown in detail).
T11873 28548-28788 Sentence denotes In part, this change may be caused by GP-mediated modulations of the TSST-1 induced binding of NFκB, NFIL-6 and NFAT to known and up to now unknown sites within the IL-8 and IL-1RA promoter instead of the TNFα, IL-1β, IL-6 or IFNγ promoter.
T11872 28342-28547 Sentence denotes Mainly, GP altered the TSST-1-induced IL-1β/IL-1RA ratio from a pro- to an anti-inflammatory profile via down-regulation of IL-1β and IL-6, at the same time there was a synergistic up-regulation of IL-1RA.
T11871 28066-28341 Sentence denotes Potentially even more relevant than the specific cytokine panel induced by GP, we found that, in the presence of other stimuli (LPS or TSST-1), GP ameliorated their pro-inflammatory immune reactions, similar to the effects in murine models of sepsis and inflammation [21-24].
T11870 27596-27824 Sentence denotes Altogether, the induction of the neutrophil-attracting IL-8 and the anti-inflammatory IL-1RA by fungal carbohydrates (GP) may well fit to a benign PAMP response, mounting defensive mechanisms against a possible microbial attack.
T11869 27358-27595 Sentence denotes A bacterial superantigen like TSST-1 acts through binding to MHC-II molecules and subsequently the T cell receptor, leading to release of mainly IFNγ and TNFα, the latter via both, PI3K and p38 mitogen-activated kinase signaling [44,45].
T11868 27176-27357 Sentence denotes Recognition of LPS is mainly mediated through Toll-like receptor 4 and subsequent signaling via the NFκB pathway, leading to expression of pro-inflammatory mediators like TNFα [43].
T11867 26989-27175 Sentence denotes This GP-induced cytokine profile was substantially more restricted than that of LPS or TSST-1, which is likely due to differences in recognition and signaling between LPS, TSST-1 and GP.
T11866 26835-26988 Sentence denotes Flow cytometric experiments seemed to confirm that monocytes and neutrophils were able to produce IL-8 just as IL-1RA in response to GP (data not shown).
T11865 26725-26834 Sentence denotes Regarding cellular sources, both, monocytes as well as neutrophils have been reported to produce IL-1RA [32].
T11864 26438-26724 Sentence denotes The differential decrease of NFκB, NFAT and NFIL-6 binding to sites in the IL-1RA promoter as well as of IL-1RA mRNA and protein induced by selective inhibitors prior to GP treatment might suggest that these steps are linked to each other and necessary for induction of IL-1RA (Fig. 7).
T11863 26157-26437 Sentence denotes Our data indicated that GP leads to production of IL-1RA primarily via induction of NFATP2/3 and NFIL-6 DNA binding, which might be due to differences in the binding motif or the composition of the activated transcription factors (NFAT) between the IFNγ, IL-6 and IL-1RA promoter.
T11862 25909-26156 Sentence denotes Analysing the IL-1RA promoter [34], we discovered four new binding sites (Fig. 8): an NFκB3 site (between -100 and -130), an NFκB consensus site (-266 and -280), another NFκB2/3 site (-288 and -302) and a more distal NFATP2/3 site (-471 and -490).
T11861 25757-25908 Sentence denotes Unlike LPS or TSST-1, we found that GP did not induce IL-1β, but it strongly induced IL-1RA, suggesting an immediate anti-inflammatory potential of GP.
T11860 25447-25756 Sentence denotes The IL-8κB consensus site exhibits a preferentially p65 binding half site and thus differs from the κB half site described for TNFα and IL-1β [27,40], supporting the idea of regulating NFκB binding through combinatorial associations of the subunits and the specific sequence of the decameric κB motif [41,42].
T11859 25269-25446 Sentence denotes A GP-mediated IL-8 transcription based upon a cooperation between transactivated NFκB p65 and NFIL-6 [13,39] or NFATc2 dimer binding to the IL-8κB site [38] seems also possible.
T11858 25029-25268 Sentence denotes Results by Schulte and colleagues [28] pointed to an induction of IL-8 transcription depending on activation via an NFκB p65/65 homodimer, rather than via p65/50 heterodimers, which might be the case for the GP-mediated IL-8 transcription.
T11857 24821-25028 Sentence denotes In addition, our EMSA/supershift and immunoblotting results demonstrated a GP-mediated predominant binding of NFκB p65 and to a lesser extent of p50 to a κB consensus site of the IL-8 promoter (Figs. 1A, 2).
T11856 24686-24820 Sentence denotes Hence, our data are in aggreement with the few reports describing a β-1→3-D-glucan-mediated IL-8 [6,16,19] and IL-1RA production [17].
T11855 24537-24685 Sentence denotes Interestingly, the GP-induced transcription factor binding transformed only into a very limited cytokine response, namely IL-8 and IL-1RA (Fig. 3B).
T11854 24334-24536 Sentence denotes Because of the multiple band shifts observed for NFAT binding (Fig. 1A), one could speculate that there is activation of several different NFAT isoforms, probably derived from alternative splicing [38].
T11853 24146-24333 Sentence denotes We confirmed and extended previous results [13-16] indicating that, in the absence of other stimuli, β-1→3-D-glucans induced binding of NFκB-, NFIL-6- and NFAT-mers to cytokine promoters.
T11852 23924-24145 Sentence denotes Our study provides novel evidence that downstream of recognition and signaling pro-inflammatory transcription factor binding and cytokine expression of human leukocytes is switched to an anti-inflammatory phenotype by GP.
T11851 23739-23923 Sentence denotes Animal models of sepsis and myocardial injury suggest that a β-1→3-D-glucan like GP mediates its protective mechanisms, in part, via a rapid shift from NFκB- to PI3K-signaling [22,37].
T10444 22641-22805 Sentence denotes Altogether, NFκB inhibition by CAPE was more pronounced at the binding activity and the transcription, whereas CyA and CHX mainly led to a decreased IL-1RA release.
T10443 22545-22640 Sentence denotes In addition, corresponding IL-1RA protein levels after 24 h of GP are shown in Fig. 7C (n = 3).
T10442 22411-22544 Sentence denotes A representative gel demonstrating a decrease in IL-1RA mRNA after inhibition with CAPE, CyA and CHX is displayed in Fig. 7B (n = 4).
T10441 22299-22410 Sentence denotes Because the highest IL-1RA amount was found at 24 h, mRNA was examined following 1 h inhibition and 18 h of GP.
T10440 22218-22298 Sentence denotes The results for the NFκB and NFIL-6 binding sites were similar (data not shown).
T10439 22055-22217 Sentence denotes The extent of reduction in NFATP2/3 binding is exemplarily shown in an autoradiogram (Fig. 7A, left side) and graphically summarized (n = 4, Fig. 7A, right side).
T9560 20564-20800 Sentence denotes A biological relevance of this result was suggested by a decrease of the IL-1 dependent release of IL-2 from murine EL-4 cells following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail, n = 4; p < 0.07).
T9559 20256-20563 Sentence denotes With respect to TSST-1 or the theoretical value of GP/TSST-1 calc. vs. GP + TSST-1, we observed a pronounced anti-inflammatory action of GP, as demonstrated by an about 10–100 fold reduced ratio at 18 h and 24 h of incubation, i.e. a higher production of IL-1RA than of IL-1β (n = 3; both p < 0.05; Fig. 6).
T9558 20078-20255 Sentence denotes Comparing LPS vs. GP + LPS, we did not find substantial alterations over a time course of 48 h in the IL-1β/IL-1RA ratio, only a – non-significant – 2.5fold higher ratio at 6 h.
T9557 19959-20077 Sentence denotes Both, LPS and GP + LPS treatments resulted in generating more IL-1β than IL-1RA at early time points, i.e. up to 24 h.
T9556 19867-19958 Sentence denotes Therefore, we applied the IL-1β/IL-1RA ratio as an indicator of the degree of inflammation.
T9555 19748-19866 Sentence denotes In a simplified approach, IL-1β and IL-1RA might represent two sides of a coin, i.e. pro- or anti-inflammatory action.
T9554 19658-19747 Sentence denotes GP modulated the TSST-1-induced IL-1β/IL-1RA ratio towards an anti-inflammatory phenotype
T4746 15360-15583 Sentence denotes When combined with TSST-1 or GP/TSST-1 calc., GP seemed to exert a synergistic effect on TNFα secretion after 36 h (n = 3; p < 0.05), but overall an enhancement of only 10% was observed (p > 0.05; data not shown in detail).
T4745 15263-15359 Sentence denotes GP + LPS did not change the TNFα production when compared to LPS supplementation or GP/LPS calc.
T4744 15126-15262 Sentence denotes With respect to TNFα production, 100 μg of GP yielded minor, statistically not distinguishable amounts, when compared to medium control.
T4743 15117-15125 Sentence denotes (v) TNFα
T4742 14932-15115 Sentence denotes Moreover, we found this correlation to be dose-dependent, since 100 μg of GP induced larger amounts of IL-8 and IL-1RA than 1 μg GP (n = 5, p ≤ 0.002, r = 0.9 and 0.98, respectively).
T4741 14834-14931 Sentence denotes Following stimulation with GP (24 h), we observed a positive correlation between IL-8 and IL-1RA.
T4740 14765-14833 Sentence denotes Positive correlation between GP-induced IL-8 and IL-1RA productions.
T4739 14654-14764 Sentence denotes Over the time course of 48 h, GP elevated the TSST-1-induced amount of IL-1RA by approximately 200% (Fig. 3B).
T4738 14419-14653 Sentence denotes However, following GP + TSST-1 we found a synergistic increase in IL-1RA production from 18 h to 48 h, when compared to TSST-1 (for instance at 24 h: n = 6; p = 0.01) or to the theoretical value of GP/TSST-1 calc. (from 18 h to 36 h).
T4737 14301-14418 Sentence denotes When compared to LPS stimulation or GP/LPS calc., GP + LPS did not alter the kinetic course of the IL-1RA production.
T4736 14150-14300 Sentence denotes Besides IL-8, IL-1RA was the only mediator which was produced in significant quantities following GP treatment, especially at 24 h (n = 14, p < 0.01).
T4735 14138-14149 Sentence denotes (iv) IL-1RA
T4734 13989-14136 Sentence denotes There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail).
T4733 13866-13988 Sentence denotes A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc.
T4732 13736-13865 Sentence denotes We found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p < 0.01).
T4731 13725-13735 Sentence denotes (iii) IL-8
T4730 13523-13723 Sentence denotes On the contrary, we observed a decreased IL-6 production for GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc., especially at 24 h by about 40% (n = 5; both p = 0.02), (data not shown in detail).
T4729 13402-13522 Sentence denotes GP induced only a small amount of IL-6 and there was no significant alteration of the LPS-induced IL-6 production by GP.
T4728 13392-13401 Sentence denotes (ii) IL-6
T4727 12076-12175 Sentence denotes On the whole, GP mediated a reduction of the TSST-1-induced amount of IL-1β by about 50% (Fig. 3A).
T4726 11880-12075 Sentence denotes For GP + TSST-1 we found a significant reduction in IL-1β from 18 h – 24 h, for the latter by about 40% when compared to TSST-1 or the theoretical value of GP/TSST-1 calc. (n = 6; both p = 0.01).
T4725 11779-11879 Sentence denotes An insignificant up-regulation of IL-1β production for GP + LPS was observed in comparison with LPS.
T4724 11691-11778 Sentence denotes There was no IL-1β production detectable following PBMC treatment with 1 nor 100 μg GP.
T4723 11681-11690 Sentence denotes (i) IL-1β
T4722 11257-11679 Sentence denotes Corroborating and extending these singular findings in terms of examining pro- (eight) as well as anti- (three) inflammatory cytokines over time (48 h) and six additional transcription factor binding sites, our comprehensive analysis revealed the following cytokine profile of human leukocytes in response to a highly purified water soluble β-1→3-D-glucan and in comparison to two pro-inflammatory mediators (LPS, TSST-1):
T4721 11138-11256 Sentence denotes Previous studies reported that β-1→3-D-glucans induced only a limited cytokine secretion of human blood cells [15-18].
T4720 10898-11137 Sentence denotes Because of the GP-induced band shifts to seven sites from the TNFα, IL-8, IL-6 and IFNγ promoters, it could be assumed that GP treatment of human PBMC would lead to production of TNFα, IL-8, IL-6, IFNγ and other pro-inflammatory mediators.
T4719 10782-10897 Sentence denotes Cytokine profile of human PBMC following a 48 h in vitro stimulation with LPS, TSST-1, GP, GP + LPS and GP + TSST-1
T3157 5849-6032 Sentence denotes Binding activities of NFκB, NFIL-6 and NFAT from human PBMC to the TNFα, IL-6 and IFNγ promoters following an in vitro stimulation (1 h) with LPS, TSST-1, GP, GP + LPS and GP + TSST-1
T3158 6033-6296 Sentence denotes GP induced band shifts, indicating binding of NFκB as well as of NFIL-6 to the corresponding DNA oligonucleotides (κ consensus, κ1, κ2, κ3 sites from the TNFα promoter; κ consensus from the IL-8 promoter; NFIL-6consensus from the IL-6 promoter; Table 1; Fig. 1A).
T3159 6297-6414 Sentence denotes The extent of the band shifts induced by GP was not statistically different when compared to LPS or TSST-1 (Fig. 1B).
T3160 6415-6588 Sentence denotes A supershift, conducted for an NFκB consensus site from the IL-8 promoter, demonstrated a GP-induced predominant binding of NFκB p65 and to a lesser degree of p50 (Fig. 1A).
T3161 6589-6757 Sentence denotes Accordingly, an immunoblot of nuclear extracts from GP-treated PBMC showed a strong binding of NFκB p65 and a weaker reaction of p50, whereas p52 was negative (Fig. 2).
T3162 6758-7147 Sentence denotes Simultaneous co-treatment of PBMC with GP did not change the LPS-induced NFκB binding to oligos from the TNFα promoter significantly (Fig. 1B), but substantially decreased the TSST-1-induced NFκB binding when compared to TSST-1 or GP (100 μg) and thus differed completely from the theoretical value of GP/TSST-1 calc. (n = 4; p < 0.05 vs. GP/TSST-1 calc. and p = 0.07 vs. TSST-1; Fig. 1B).
T3163 7148-7285 Sentence denotes GP was also able to induce band shifts indicative of binding of particular variants of NFAT to an oligo from the IFNγ promoter (Fig. 1A).
T3164 7286-7408 Sentence denotes An immunoblot for two NFAT subunits demonstrated a GP-induced binding of NFATc2 and to a lesser degree of NFATc1 (Fig. 2).
T26163 7418-7465 Sentence denotes Sense strand of oligonucleotides used in EMSAs.
T10438 21768-22054 Sentence denotes As expected, an inhibition of NFκB via CAPE [35] and CyA, NFAT via CyA and NFIL-6 via CHX [36] could not be overruled by GP, leading to a down-regulated binding activity of the transcription factors to the IL-1RA sites, and a reduction of IL-1RA mRNA and IL-1RA protein levels (Fig. 7).
T10437 21605-21767 Sentence denotes Pharmacological inhibitors were used to demonstrate that the transcription factor sites within the IL-1RA promoter are relevant for the induction of IL-1RA by GP.
T10436 21540-21604 Sentence denotes Inhibition of transcription factors led to reduced IL-1RA levels
T8018 18209-18506 Sentence denotes In addition, binding to the NFATP2/3 site following both, GP + LPS (1.4fold of GP) and GP + TSST-1 (1.5fold of GP, 1.25fold of TSST-1) was elevated (p < 0.05; Fig. 5), but only in an additive synergistic manner, i.e. the experimental results were not different from the theoretical values (calc.).
T8017 17968-18208 Sentence denotes A new binding site for NFATP2/3 was found more distal of the transcription start site, between -471 and -490, displaying again a substantial increase of binding for all compounds and combinations, when compared to medium control (p < 0.05).
T8016 17818-17967 Sentence denotes Further, GP + TSST-1 induced an increased binding to the NFIL-6 site in comparison with TSST-1 (1.3fold) or GP (1.6fold; p < 0.05), (data not shown).
T8015 17640-17817 Sentence denotes The NFIL-6 site (-147 and -170) close to LRE-2 [31,32] showed an up-regulation of binding for all compounds and combinations vs. medium control, ranging from 25–110% (p < 0.05).
T8014 17458-17639 Sentence denotes The LPS-, TSST-1- and GP + LPS-induced binding to the new κB2/3 site (-288 and -302) was down-regulated by about 20–35% in comparison with medium control (p < 0.05; data not shown).
T8013 17328-17457 Sentence denotes Binding to a new κB consensus site (between -266 and -280) was significantly elevated for GP + TSST-1 (p < 0.05; data not shown).
T8012 16911-17327 Sentence denotes A new κB3 site (-100 and -130) within the LRE-1 [30] showed increased binding induced by TSST-1 (+30% vs. control), but GP co-treatment up-regulated the LPS (+65% vs. control)- and the TSST-1 (+110% vs. control)-induced binding in a superadditive synergistic fashion, when compared to medium control as well as to LPS, TSST-1 or GP or the theoretical values of GP/LPS calc. or GP/TSST-1 calc. (all p < 0.05; Fig. 4).
T8011 16711-16910 Sentence denotes The LPS responsive κB consensus site of LRE-1 (between -84 and -93) [30] displayed band shifts, but no significant alterations of its binding activity, irrespective of the treatment (data not shown).
T8010 16520-16710 Sentence denotes We investigated previoulsy described and newly discovered transcription factor binding sites of the IL-1RA promoter (Table 1) using the program OMIGA (v.1.1.3, Oxford Molecular, Oxford, UK).
T8009 16329-16519 Sentence denotes Because GP induced band shifts to NFκB, NFIL-6 and NFAT sites, but no TNFα, IL-6 or IFNγ, we hypothesized that the activated transcription factors might bind to sites in the IL-1RA promoter.
T8008 16202-16328 Sentence denotes Role of NFκB, NFIL-6 and NFAT binding in LPS-, TSST-1-, GP-, GP + LPS- and GP + TSST-1-induced IL-1RA expression by human PBMC
T17940 34156-34325 Sentence denotes For induction of transcription factors and cytokines, PBMC were cultured in a volume of 4 ml in sterile pyrogen-free 6-well culture plates (Falcon, Heidelberg, Germany).
T17939 34133-34155 Sentence denotes Stimulation conditions
T17464 33161-33388 Sentence denotes GP was dissolved in aqueous media, filter-sterilized (0.2 μm) and screened for endotoxin contamination with the Endospecy assay (Seigakaku, Tokyo, Japan), which is specific for endotoxin but does not respond to β-1→3-D-glucans.
T17463 33071-33160 Sentence denotes The physicochemical characteristics of GP were determined as reported previously [20,26].
T17462 32988-33070 Sentence denotes Water soluble phosphorylated β-1→3-D-glucan (GP) was prepared as done before [20].
T17461 32978-32987 Sentence denotes Materials
T17107 32744-32967 Sentence denotes Together with the in vivo studies [22,37], our findings might support the concept of protective effects mediated by glucan phosphate in pro-inflammatory conditions, especially with a dysregulated IL-1β/IL-1RA ratio [52,53].
T17106 32501-32743 Sentence denotes Our results also generated new insights into a very complex interplay of transcription factor binding to various known and newly identified sites in the IL-1RA promoter (Fig. 8), which can be regulated differentially by a fungal carbohydrate.
T17105 32206-32500 Sentence denotes In summary, our data demonstrated that in vitro glucan phosphate induced a transcription factor binding and a subsequent cytokine profile different from LPS and also from TSST-1 and, moreover, switched a pro-inflammatory TSST-1-induced response to an IL-1RA-mediated anti-inflammatory reaction.
T4752 16031-16200 Sentence denotes There were also no significant differences between medium control, LPS, TSST-1, GP, GP + LPS, GP/LPS calc. and GP + TSST-1 or GP/TSST-1 calc. over 48 h (data not shown).
T4751 15954-16030 Sentence denotes The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1 was not induced by GP.
T4750 15916-15953 Sentence denotes (vii) IL-2, IL-12, IL-4, IL-10, TGFβ1
T4749 15673-15914 Sentence denotes There was a minor increase in IFNγ production following GP + LPS at 36 h, when compared to LPS or GP/LPS calc., and a slight down-regulation following GP + TSST-1 at 24 h and 36 h, when compared to TSST-1 or GP/TSST-1 calc. (data not shown).
T4748 15595-15672 Sentence denotes No IFNγ production was detectable following treatment of PBMC with 100 μg GP.
T4747 15585-15594 Sentence denotes (vi) IFNγ
T1072 2268-2446 Sentence denotes β-1→3-D-glucans occur as a principal component of microbial cell walls or can be secreted from both, non-pathogenic and pathogenic fungi such as S. cerevisae and C. albicans [1].
T1073 2447-2564 Sentence denotes These β-1→3-D-linked glucose polymers are characterized as a fungal pathogen-associated molecular pattern (PAMP) [2].
T1074 2565-2707 Sentence denotes The primary cellular recognition of β-1→3-D-glucans is mediated by several β-1→3-D-glucan receptors on phagocytes [3,4] and other cells [5,6].
T1075 2708-2962 Sentence denotes Human as well as murine Dectin-1 has been demonstrated to be the major pattern recognition receptor (PRR) for intact yeast and β-1→3-D-glucan-containing particles (i.e. zymosan) on monocytes/macrophages as well as neutrophils and on primary cells [7-11].
T1076 2963-3111 Sentence denotes In the murine system, binding of zymosan to Dectin-1 resulted in production of TNFα through Toll-like receptor 2 and the adaptor protein MyD88 [12].
T1077 3112-3238 Sentence denotes Another water-soluble β-1→3-D-glucan (PGG-glucan) has been described to activate NFκB and NFIL-6 in murine cell lines [13,14].
T1078 3239-3484 Sentence denotes Similarly, it has been shown that β-1→3-D-glucans activate NFκB in a human monocyte-like cell line [15] and in human polymorphonuclear neutrophils (PMN), in the latter case without secretion of pro-inflammatory cytokines (IL-1, IL-6, TNFα) [16].
T1079 3485-3662 Sentence denotes One study proposed that the production of the anti-inflammatory IL-1RA, but not IL-1 by human monocytes may be a potentially protective mechanism induced by β-1→3-D-glucan [17].
T1080 3663-3845 Sentence denotes Three other investigations have reported that human leukocytes and human vascular endothelial cells produce IL-8 in response to zymosan [18] or a water-soluble β-1→3-D-glucan [6,19].
T1081 3846-3957 Sentence denotes In addition, β-1→3-D-glucans seem to be able to modify the response to pro-inflammatory stimuli or even sepsis.
T1082 3958-4185 Sentence denotes In a murine polymicrobial sepsis model, β-1→3-D-glucan [20] treatment resulted in decreased septic morbidity and mortality mediated via inhibition of NFκB and stimulation of the phosphoinositide-3-kinase (PI3K) pathway [21,22].
T1083 4186-4341 Sentence denotes These and other animal studies [23,24] as well as a clinical trial [25] support a protective role of β-1→3-D-glucan in certain pro-inflammatory conditions.
T1084 4342-4461 Sentence denotes The mechanisms underlying these beneficial effects of β-1→3-D-glucan are only partially resolved, especially in humans.
T1085 4462-4692 Sentence denotes Thus, the aim of this study was to elucidate molecular and cellular mechanisms of β-1→3-D-glucans on human leukocytes in pro-inflammatory conditions with special emphasis on the cytokine profile and its transcriptional regulation.
T1086 4693-4962 Sentence denotes For this purpose, peripheral blood mononuclear cells (PBMC) were exposed to a well-defined β-1→3-D-glucan, i.e. glucan phosphate (GP) [20,26], alone or simultaneously with LPS from gram-negative bacteria or the superantigen TSST-1 from gram-positive bacteria over 48 h.
T1087 4963-5149 Sentence denotes Because of the potential effect of β-1→3-D-glucan on cytokine production [12,16-19], TNFα, IL-1β, IL-6, IL-8 and IL-1RA were measured as well as IFNγ, IL-2, IL-4, IL-10, IL-12 and TGFβ1.
T1088 5150-5404 Sentence denotes Correspondingly, four NFκB sites from the TNFα promoter (κ consensus, κ1, κ2, κ3) [27], a κ consensus site from the IL-8 promoter [28], an NFAT site from the IFNγ promoter (ATP2) [29] and a consensus NFIL-6 site from the IL-6 promoter [13] were examined.
T1089 5405-5524 Sentence denotes Because of the anti-inflammatory role of IL-1RA, we focused on binding of transcription factors to the IL-1RA promoter.
T1090 5525-5726 Sentence denotes An inhibitory element and three positive-acting LPS-response elements (LRE-1, LRE-2 and LRE-3) in the IL-1RA promoter, including NFκB, PU.1 and NFIL-6 sites, have been characterized previously [30-33].
T1091 5727-5838 Sentence denotes Using computational analysis for homology search [34], we looked for new binding motifs in the IL-1RA promoter.
T1 0-155 Sentence denotes β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio
T2 157-165 Sentence denotes Abstract
T3 166-176 Sentence denotes Background
T4 177-287 Sentence denotes β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses.
T5 288-610 Sentence denotes Employing a comprehensive methodological approach, the aim of our in vitro study was to elucidate novel molecular and cellular mechanisms of human peripheral blood immune cells mediated by a fungal β-1→3-D-glucan, i.e. glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1).
T6 612-619 Sentence denotes Results
T7 620-845 Sentence denotes Despite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate.
T8 846-933 Sentence denotes Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h:
T9 934-1018 Sentence denotes 5000 pg/ml), likely due to binding of NFκB to a consensus site in the IL-8 promoter.
T10 1019-1087 Sentence denotes An increase in IL-1receptor antagonist(RA) production (peak at 24 h:
T11 1088-1174 Sentence denotes 12000 pg/ml) by glucan phosphate-treated cells positively correlated with IL-8 levels.
T12 1175-1337 Sentence denotes Glucan phosphate induced significant binding to a known NFIL-6 site and a new NFAT site within the IL-1RA promoter, which was confirmed by inhibition experiments.
T13 1338-1574 Sentence denotes When applied in combination with either LPS or TSST-1 at the same time points, we detected that glucan phosphate elevated the LPS- and the TSST-1-induced DNA binding of NFκB, NFIL-6 and NFAT, leading to a synergistic increase of IL-1RA.
T14 1575-1684 Sentence denotes Further, glucan phosphate modulated the TSST-1-induced inflammatory response via reduction of IL-1β and IL-6.
T15 1685-1805 Sentence denotes As a consequence, glucan phosphate shifted the TSST-1-induced IL-1β/IL-1RA ratio towards an anti-inflammatory phenotype.
T16 1806-1901 Sentence denotes Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2.
T17 1903-1913 Sentence denotes Conclusion
T18 1914-2127 Sentence denotes Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction.
T19 2128-2255 Sentence denotes Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan.
T20 2257-2267 Sentence denotes Background
T21 2268-2446 Sentence denotes β-1→3-D-glucans occur as a principal component of microbial cell walls or can be secreted from both, non-pathogenic and pathogenic fungi such as S. cerevisae and C. albicans [1].
T22 2447-2564 Sentence denotes These β-1→3-D-linked glucose polymers are characterized as a fungal pathogen-associated molecular pattern (PAMP) [2].
T23 2565-2707 Sentence denotes The primary cellular recognition of β-1→3-D-glucans is mediated by several β-1→3-D-glucan receptors on phagocytes [3,4] and other cells [5,6].
T24 2708-2962 Sentence denotes Human as well as murine Dectin-1 has been demonstrated to be the major pattern recognition receptor (PRR) for intact yeast and β-1→3-D-glucan-containing particles (i.e. zymosan) on monocytes/macrophages as well as neutrophils and on primary cells [7-11].
T25 2963-3111 Sentence denotes In the murine system, binding of zymosan to Dectin-1 resulted in production of TNFα through Toll-like receptor 2 and the adaptor protein MyD88 [12].
T26 3112-3238 Sentence denotes Another water-soluble β-1→3-D-glucan (PGG-glucan) has been described to activate NFκB and NFIL-6 in murine cell lines [13,14].
T27 3239-3484 Sentence denotes Similarly, it has been shown that β-1→3-D-glucans activate NFκB in a human monocyte-like cell line [15] and in human polymorphonuclear neutrophils (PMN), in the latter case without secretion of pro-inflammatory cytokines (IL-1, IL-6, TNFα) [16].
T28 3485-3662 Sentence denotes One study proposed that the production of the anti-inflammatory IL-1RA, but not IL-1 by human monocytes may be a potentially protective mechanism induced by β-1→3-D-glucan [17].
T29 3663-3845 Sentence denotes Three other investigations have reported that human leukocytes and human vascular endothelial cells produce IL-8 in response to zymosan [18] or a water-soluble β-1→3-D-glucan [6,19].
T30 3846-3957 Sentence denotes In addition, β-1→3-D-glucans seem to be able to modify the response to pro-inflammatory stimuli or even sepsis.
T31 3958-4185 Sentence denotes In a murine polymicrobial sepsis model, β-1→3-D-glucan [20] treatment resulted in decreased septic morbidity and mortality mediated via inhibition of NFκB and stimulation of the phosphoinositide-3-kinase (PI3K) pathway [21,22].
T32 4186-4341 Sentence denotes These and other animal studies [23,24] as well as a clinical trial [25] support a protective role of β-1→3-D-glucan in certain pro-inflammatory conditions.
T33 4342-4461 Sentence denotes The mechanisms underlying these beneficial effects of β-1→3-D-glucan are only partially resolved, especially in humans.
T34 4462-4692 Sentence denotes Thus, the aim of this study was to elucidate molecular and cellular mechanisms of β-1→3-D-glucans on human leukocytes in pro-inflammatory conditions with special emphasis on the cytokine profile and its transcriptional regulation.
T35 4693-4962 Sentence denotes For this purpose, peripheral blood mononuclear cells (PBMC) were exposed to a well-defined β-1→3-D-glucan, i.e. glucan phosphate (GP) [20,26], alone or simultaneously with LPS from gram-negative bacteria or the superantigen TSST-1 from gram-positive bacteria over 48 h.
T36 4963-5149 Sentence denotes Because of the potential effect of β-1→3-D-glucan on cytokine production [12,16-19], TNFα, IL-1β, IL-6, IL-8 and IL-1RA were measured as well as IFNγ, IL-2, IL-4, IL-10, IL-12 and TGFβ1.
T37 5150-5404 Sentence denotes Correspondingly, four NFκB sites from the TNFα promoter (κ consensus, κ1, κ2, κ3) [27], a κ consensus site from the IL-8 promoter [28], an NFAT site from the IFNγ promoter (ATP2) [29] and a consensus NFIL-6 site from the IL-6 promoter [13] were examined.
T38 5405-5524 Sentence denotes Because of the anti-inflammatory role of IL-1RA, we focused on binding of transcription factors to the IL-1RA promoter.
T39 5525-5726 Sentence denotes An inhibitory element and three positive-acting LPS-response elements (LRE-1, LRE-2 and LRE-3) in the IL-1RA promoter, including NFκB, PU.1 and NFIL-6 sites, have been characterized previously [30-33].
T40 5727-5838 Sentence denotes Using computational analysis for homology search [34], we looked for new binding motifs in the IL-1RA promoter.
T41 5840-5847 Sentence denotes Results
T42 5849-6032 Sentence denotes Binding activities of NFκB, NFIL-6 and NFAT from human PBMC to the TNFα, IL-6 and IFNγ promoters following an in vitro stimulation (1 h) with LPS, TSST-1, GP, GP + LPS and GP + TSST-1
T43 6033-6296 Sentence denotes GP induced band shifts, indicating binding of NFκB as well as of NFIL-6 to the corresponding DNA oligonucleotides (κ consensus, κ1, κ2, κ3 sites from the TNFα promoter; κ consensus from the IL-8 promoter; NFIL-6consensus from the IL-6 promoter; Table 1; Fig. 1A).
T44 6297-6414 Sentence denotes The extent of the band shifts induced by GP was not statistically different when compared to LPS or TSST-1 (Fig. 1B).
T45 6415-6588 Sentence denotes A supershift, conducted for an NFκB consensus site from the IL-8 promoter, demonstrated a GP-induced predominant binding of NFκB p65 and to a lesser degree of p50 (Fig. 1A).
T46 6589-6757 Sentence denotes Accordingly, an immunoblot of nuclear extracts from GP-treated PBMC showed a strong binding of NFκB p65 and a weaker reaction of p50, whereas p52 was negative (Fig. 2).
T47 6758-7147 Sentence denotes Simultaneous co-treatment of PBMC with GP did not change the LPS-induced NFκB binding to oligos from the TNFα promoter significantly (Fig. 1B), but substantially decreased the TSST-1-induced NFκB binding when compared to TSST-1 or GP (100 μg) and thus differed completely from the theoretical value of GP/TSST-1 calc. (n = 4; p < 0.05 vs. GP/TSST-1 calc. and p = 0.07 vs. TSST-1; Fig. 1B).
T48 7148-7285 Sentence denotes GP was also able to induce band shifts indicative of binding of particular variants of NFAT to an oligo from the IFNγ promoter (Fig. 1A).
T49 7286-7408 Sentence denotes An immunoblot for two NFAT subunits demonstrated a GP-induced binding of NFATc2 and to a lesser degree of NFATc1 (Fig. 2).
T50 7409-7465 Sentence denotes Table 1 Sense strand of oligonucleotides used in EMSAs.
T51 7466-7596 Sentence denotes Oligonucleotidesa Base sequences (5'- XXX -3') binding site/cytokine gene promoter (position of the cytokine gene from the TSS)b
T52 7597-7683 Sentence denotes NFκBcS GAT CCT CAG AGG GGA CTT TCCc GAT G NFκB consensus sequence/TNFα promoter [27]
T53 7684-7750 Sentence denotes NFκB1S GAT CCT GGG ACA GCC CAG NFκB1 sequence/TNFα promoter [27]
T54 7751-7815 Sentence denotes NFκB2S GAT CCG GGG TAT CCT G NFκB2 sequence/TNFα promoter [27]
T55 7816-7881 Sentence denotes NFκB3S GAT CCT GGG TTT CTC CG NFκB3 sequence/TNFα promoter [27]
T56 7882-7961 Sentence denotes IL-8κBcS ATC GTG GAA TTT CCT CTG A NFκB consensus sequence/IL-8 promoter [28]
T57 7962-8037 Sentence denotes NFATP2S GAT CTA AAA TTT CCA GTC CTT GA NFATP2 sequence/IFNγ promoter [29]
T58 8038-8119 Sentence denotes NFIL-6S TGC AGA TTG CGC AAT CTG CA NFIL-6 consensus sequence/IL-6 promoter [13]
T59 8120-8213 Sentence denotes NFκBcS GCG AGG AGG GTA TTT CCG CTT between -80 and -100 NFκB consensus/IL-1RA promoter [30]
T60 8214-8306 Sentence denotes NFκB3S ACA ACA GCA AGG GTT TCT CTT TTT GGA AAT between -100 and -130 NFκB3/IL-1RA promoter
T61 8307-8397 Sentence denotes NFκBcS AGT AGG GAG TTT GGT between -266 and -280 NFκB consensus sequence/IL-1RA promoter
T62 8398-8483 Sentence denotes NFκB2/3S ACT CTG GGT ACC TGT between -288 and -302 NFκB2/3 sequence/IL-1RA promoter
T63 8484-8591 Sentence denotes NFATP2/3S GGC GCA CAA AAC CTA AAA TAT TTA CTA TCT between -471 and -500 NFATP2/3 sequence/IL-1RA promoter
T64 8592-8700 Sentence denotes NFIL-6S TTA CAA CAC TCC ATT GCG ACA CTT AGT GGG between -140 and -170 NFIL-6 sequence/IL-1RA promoter [31]
T65 8701-8869 Sentence denotes Oct-1 DNAS AAT TGC ATT GCC TGC AGG TCG ACT CTA GAG GAT CCA TGC AAA TGG ATC CCC GGG TAC CGA GCT C exclusion of unspecific bindings, unrelated DNA, (Amersham Pharmacia)
T66 8870-8873 Sentence denotes (a:
T67 8874-8948 Sentence denotes S = sense; b: TSS = transcription start site;c: ___ = main binding motif).
T68 8949-9009 Sentence denotes Figure 1 A, GP led to DNA binding of NFAT, NFκB and NFIL-6.
T69 9010-9093 Sentence denotes Human PBMC were incubated with medium control or GP (1 and 100 μg) for 1 h at 37°C.
T70 9094-9271 Sentence denotes Nuclear extracts were incubated with a 32P-labeled NFAT, NFκB, NFIL-6 or NFκB-IL-8 oligonucleotide probe corresponding to the IFNγ, TNFα, IL-6 and IL-8 gene promoters (Table 1).
T71 9272-9426 Sentence denotes Arrows with the black head indicate migrational location of the NFAT-DNA, NFκB-DNA, NFIL-6-DNA or NFκB-IL-8-DNA complex compared to free probe (no shift).
T72 9427-9524 Sentence denotes Arrow with the open head indicates a supershift of NFκB-IL-8-DNA-anti-p65 and -p50, respectively.
T73 9525-9592 Sentence denotes An autoradiogram from a representative experiment is shown (n = 7).
T74 9593-9686 Sentence denotes B, Decreased DNA binding of NFκB following GP + TSST-1, compared to TSST-1, GP, or TSST-1/GP.
T75 9687-9801 Sentence denotes Human PBMC were incubated with medium control, LPS, TSST-1, GP (100 μg), GP + TSST-1 and GP + LPS for 1 h at 37°C.
T76 9802-9861 Sentence denotes An autoradiogram from a representative experiment is shown.
T77 9862-10074 Sentence denotes Schematic representation of NFκB-DNA binding activity following GP (1 and 100 μg) or TSST-1 treatment (250 ng) as well as simultaneous administration of both compounds and the theoretical value (GP/TSST-1 calc.).
T78 10075-10204 Sentence denotes Medium control levels were set equal to 1± SEM and significances (* = p < 0.05) are shown with respect to medium control (n = 4).
T79 10205-10282 Sentence denotes Figure 2 NFκB p65/p50 and NFATc2/c1 were involved in GP-induced DNA binding.
T80 10283-10419 Sentence denotes In order to determine whether the DNA binding proteins activated by GP were related to NFκB and NFAT, an immuno(dot) blot was performed.
T81 10420-10780 Sentence denotes A representative dot blot showing staining of negative and positive controls (recombinant proteins NFκB p52, c-rel; nuclear extracts of PMA-treated Jurkat cells positive for NFκB p50, p65 and for NFATc1, c2) in the upper panel and staining of nuclear extracts of GP-treated PBMC (positive for NFκB p65, p50 and NFAT c2, c1) in the lower panel is shown (n = 3).
T82 10782-10897 Sentence denotes Cytokine profile of human PBMC following a 48 h in vitro stimulation with LPS, TSST-1, GP, GP + LPS and GP + TSST-1
T83 10898-11137 Sentence denotes Because of the GP-induced band shifts to seven sites from the TNFα, IL-8, IL-6 and IFNγ promoters, it could be assumed that GP treatment of human PBMC would lead to production of TNFα, IL-8, IL-6, IFNγ and other pro-inflammatory mediators.
T84 11138-11256 Sentence denotes Previous studies reported that β-1→3-D-glucans induced only a limited cytokine secretion of human blood cells [15-18].
T85 11257-11679 Sentence denotes Corroborating and extending these singular findings in terms of examining pro- (eight) as well as anti- (three) inflammatory cytokines over time (48 h) and six additional transcription factor binding sites, our comprehensive analysis revealed the following cytokine profile of human leukocytes in response to a highly purified water soluble β-1→3-D-glucan and in comparison to two pro-inflammatory mediators (LPS, TSST-1):
T86 11681-11690 Sentence denotes (i) IL-1β
T87 11691-11778 Sentence denotes There was no IL-1β production detectable following PBMC treatment with 1 nor 100 μg GP.
T88 11779-11879 Sentence denotes An insignificant up-regulation of IL-1β production for GP + LPS was observed in comparison with LPS.
T89 11880-12075 Sentence denotes For GP + TSST-1 we found a significant reduction in IL-1β from 18 h – 24 h, for the latter by about 40% when compared to TSST-1 or the theoretical value of GP/TSST-1 calc. (n = 6; both p = 0.01).
T90 12076-12175 Sentence denotes On the whole, GP mediated a reduction of the TSST-1-induced amount of IL-1β by about 50% (Fig. 3A).
T91 12176-12274 Sentence denotes Figure 3 A, IL-1β was down-regulated (12 h – 24 h) following GP + TSST-1 when compared to TSST-1.
T92 12275-12430 Sentence denotes Time course (48 h) of IL-1β production (pg/ml) by human PBMC incubated with medium control, 100 μg GP, 250 ng TSST-1, GP + TSST-1, 250 ng LPS and GP + LPS.
T93 12431-12558 Sentence denotes At 18 h and 24 h there was a marked reduction in IL-1β production following GP + TSST-1 when compared to TSST-1 (* = p < 0.05).
T94 12559-12651 Sentence denotes Graphs depicting the theoretical values for GP/LPS calc. and GP/TSST-1 calc. are also shown.
T95 12652-12744 Sentence denotes IL-1β levels in the supernatnant were obtained by Elisa and are shown as mean ± SEM (n = 3).
T96 12745-12831 Sentence denotes B, IL-1RA was exaggerated following GP + TSST-1 (12 h – 48 h) when compared to TSST-1.
T97 12832-12988 Sentence denotes Time course (48 h) of IL-1RA production (pg/ml) by human PBMC incubated with medium control, 100 μg GP, 250 ng TSST-1, GP + TSST-1, 250 ng LPS and GP + LPS.
T98 12989-13205 Sentence denotes Between 18 h and 48 h a simultaneous treatment of PBMC with GP + TSST-1 led to a synergistic effect, i.e. a higher IL-1RA production when compared to an addition of the single values for TSST-1 and GP (* = p < 0.05).
T99 13206-13296 Sentence denotes Graphs depicting the theoretical values for GP/LPS calc. and GP/TSST-1 calc. are included.
T100 13297-13390 Sentence denotes IL-1RA levels in the supernatnant were obtained by Elisa and are shown as mean ± SEM (n = 3).
T101 13392-13401 Sentence denotes (ii) IL-6
T102 13402-13522 Sentence denotes GP induced only a small amount of IL-6 and there was no significant alteration of the LPS-induced IL-6 production by GP.
T103 13523-13723 Sentence denotes On the contrary, we observed a decreased IL-6 production for GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc., especially at 24 h by about 40% (n = 5; both p = 0.02), (data not shown in detail).
T104 13725-13735 Sentence denotes (iii) IL-8
T105 13736-13865 Sentence denotes We found that GP induced a substantial IL-8 production, in comparison with medium control, especially at 24 h (n = 13; p < 0.01).
T106 13866-13988 Sentence denotes A combination of GP and LPS resulted in a non-significant increase of IL-8 production when compared to LPS or GP/LPS calc.
T107 13989-14136 Sentence denotes There was no significant alteration in IL-8 production following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail).
T108 14138-14149 Sentence denotes (iv) IL-1RA
T109 14150-14300 Sentence denotes Besides IL-8, IL-1RA was the only mediator which was produced in significant quantities following GP treatment, especially at 24 h (n = 14, p < 0.01).
T110 14301-14418 Sentence denotes When compared to LPS stimulation or GP/LPS calc., GP + LPS did not alter the kinetic course of the IL-1RA production.
T111 14419-14653 Sentence denotes However, following GP + TSST-1 we found a synergistic increase in IL-1RA production from 18 h to 48 h, when compared to TSST-1 (for instance at 24 h: n = 6; p = 0.01) or to the theoretical value of GP/TSST-1 calc. (from 18 h to 36 h).
T112 14654-14764 Sentence denotes Over the time course of 48 h, GP elevated the TSST-1-induced amount of IL-1RA by approximately 200% (Fig. 3B).
T113 14765-14833 Sentence denotes Positive correlation between GP-induced IL-8 and IL-1RA productions.
T114 14834-14931 Sentence denotes Following stimulation with GP (24 h), we observed a positive correlation between IL-8 and IL-1RA.
T115 14932-15115 Sentence denotes Moreover, we found this correlation to be dose-dependent, since 100 μg of GP induced larger amounts of IL-8 and IL-1RA than 1 μg GP (n = 5, p ≤ 0.002, r = 0.9 and 0.98, respectively).
T116 15117-15125 Sentence denotes (v) TNFα
T117 15126-15262 Sentence denotes With respect to TNFα production, 100 μg of GP yielded minor, statistically not distinguishable amounts, when compared to medium control.
T118 15263-15359 Sentence denotes GP + LPS did not change the TNFα production when compared to LPS supplementation or GP/LPS calc.
T119 15360-15583 Sentence denotes When combined with TSST-1 or GP/TSST-1 calc., GP seemed to exert a synergistic effect on TNFα secretion after 36 h (n = 3; p < 0.05), but overall an enhancement of only 10% was observed (p > 0.05; data not shown in detail).
T120 15585-15594 Sentence denotes (vi) IFNγ
T121 15595-15672 Sentence denotes No IFNγ production was detectable following treatment of PBMC with 100 μg GP.
T122 15673-15914 Sentence denotes There was a minor increase in IFNγ production following GP + LPS at 36 h, when compared to LPS or GP/LPS calc., and a slight down-regulation following GP + TSST-1 at 24 h and 36 h, when compared to TSST-1 or GP/TSST-1 calc. (data not shown).
T123 15916-15953 Sentence denotes (vii) IL-2, IL-12, IL-4, IL-10, TGFβ1
T124 15954-16030 Sentence denotes The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1 was not induced by GP.
T125 16031-16200 Sentence denotes There were also no significant differences between medium control, LPS, TSST-1, GP, GP + LPS, GP/LPS calc. and GP + TSST-1 or GP/TSST-1 calc. over 48 h (data not shown).
T126 16202-16328 Sentence denotes Role of NFκB, NFIL-6 and NFAT binding in LPS-, TSST-1-, GP-, GP + LPS- and GP + TSST-1-induced IL-1RA expression by human PBMC
T127 16329-16519 Sentence denotes Because GP induced band shifts to NFκB, NFIL-6 and NFAT sites, but no TNFα, IL-6 or IFNγ, we hypothesized that the activated transcription factors might bind to sites in the IL-1RA promoter.
T128 16520-16710 Sentence denotes We investigated previoulsy described and newly discovered transcription factor binding sites of the IL-1RA promoter (Table 1) using the program OMIGA (v.1.1.3, Oxford Molecular, Oxford, UK).
T129 16711-16910 Sentence denotes The LPS responsive κB consensus site of LRE-1 (between -84 and -93) [30] displayed band shifts, but no significant alterations of its binding activity, irrespective of the treatment (data not shown).
T130 16911-17327 Sentence denotes A new κB3 site (-100 and -130) within the LRE-1 [30] showed increased binding induced by TSST-1 (+30% vs. control), but GP co-treatment up-regulated the LPS (+65% vs. control)- and the TSST-1 (+110% vs. control)-induced binding in a superadditive synergistic fashion, when compared to medium control as well as to LPS, TSST-1 or GP or the theoretical values of GP/LPS calc. or GP/TSST-1 calc. (all p < 0.05; Fig. 4).
T131 17328-17457 Sentence denotes Binding to a new κB consensus site (between -266 and -280) was significantly elevated for GP + TSST-1 (p < 0.05; data not shown).
T132 17458-17639 Sentence denotes The LPS-, TSST-1- and GP + LPS-induced binding to the new κB2/3 site (-288 and -302) was down-regulated by about 20–35% in comparison with medium control (p < 0.05; data not shown).
T133 17640-17817 Sentence denotes The NFIL-6 site (-147 and -170) close to LRE-2 [31,32] showed an up-regulation of binding for all compounds and combinations vs. medium control, ranging from 25–110% (p < 0.05).
T134 17818-17967 Sentence denotes Further, GP + TSST-1 induced an increased binding to the NFIL-6 site in comparison with TSST-1 (1.3fold) or GP (1.6fold; p < 0.05), (data not shown).
T135 17968-18208 Sentence denotes A new binding site for NFATP2/3 was found more distal of the transcription start site, between -471 and -490, displaying again a substantial increase of binding for all compounds and combinations, when compared to medium control (p < 0.05).
T136 18209-18506 Sentence denotes In addition, binding to the NFATP2/3 site following both, GP + LPS (1.4fold of GP) and GP + TSST-1 (1.5fold of GP, 1.25fold of TSST-1) was elevated (p < 0.05; Fig. 5), but only in an additive synergistic manner, i.e. the experimental results were not different from the theoretical values (calc.).
T137 18507-18605 Sentence denotes Figure 4 GP modulated LPS- and TSST-1-induced binding to a new NFκB3 site in the IL-1RA promoter.
T138 18606-18767 Sentence denotes Binding was enhanced for GP + LPS and GP + TSST-1, when compared to LPS, TSST-1, GP, GP/LPS calc. or GP/TSST-1 calc., respectively (* = p < 0.05; ** = p < 0.01).
T139 18768-18824 Sentence denotes Medium control levels were set equal to 1 ± SEM (n = 6).
T140 18825-18872 Sentence denotes DNA binding was assessed by EMSA (see methods).
T141 18873-18969 Sentence denotes Figure 5 GP modulated TSST-1-induced DNA binding to a new NFATP2/3 site in the IL-1RA promoter.
T142 18970-19107 Sentence denotes Binding was up-regulated for GP + LPS and GP + TSST-1, when compared to GP and, in the latter case, to both GP and TSST-1 (* = p < 0.05).
T143 19108-19213 Sentence denotes Human PBMC were incubated with medium control, LPS, TSST-1, GP, GP + TSST-1 and GP + LPS for 1 h at 37°C.
T144 19214-19316 Sentence denotes Schematic representation of the elevated NFAT-DNA binding activity to the site in the IL-1RA promoter.
T145 19317-19402 Sentence denotes Bars depicting the theoretical values for GP/LPS calc. and GP/TSST-1 calc. are added.
T146 19403-19459 Sentence denotes Medium control levels were set equal to 1 ± SEM (n = 6).
T147 19460-19656 Sentence denotes An autoradiogram of a representative experiment is shown in the lower panel (lane 1: water; lane 2: medium control; lane 3: GP; lane 4: LPS; lane 5: TSST-1, lane 6: GP + LPS; lane 7: GP + TSST-1).
T148 19658-19747 Sentence denotes GP modulated the TSST-1-induced IL-1β/IL-1RA ratio towards an anti-inflammatory phenotype
T149 19748-19866 Sentence denotes In a simplified approach, IL-1β and IL-1RA might represent two sides of a coin, i.e. pro- or anti-inflammatory action.
T150 19867-19958 Sentence denotes Therefore, we applied the IL-1β/IL-1RA ratio as an indicator of the degree of inflammation.
T151 19959-20077 Sentence denotes Both, LPS and GP + LPS treatments resulted in generating more IL-1β than IL-1RA at early time points, i.e. up to 24 h.
T152 20078-20255 Sentence denotes Comparing LPS vs. GP + LPS, we did not find substantial alterations over a time course of 48 h in the IL-1β/IL-1RA ratio, only a – non-significant – 2.5fold higher ratio at 6 h.
T153 20256-20563 Sentence denotes With respect to TSST-1 or the theoretical value of GP/TSST-1 calc. vs. GP + TSST-1, we observed a pronounced anti-inflammatory action of GP, as demonstrated by an about 10–100 fold reduced ratio at 18 h and 24 h of incubation, i.e. a higher production of IL-1RA than of IL-1β (n = 3; both p < 0.05; Fig. 6).
T154 20564-20800 Sentence denotes A biological relevance of this result was suggested by a decrease of the IL-1 dependent release of IL-2 from murine EL-4 cells following GP + TSST-1 when compared to TSST-1 or GP/TSST-1 calc. (data not shown in detail, n = 4; p < 0.07).
T155 20801-20886 Sentence denotes Figure 6 Decreased IL-1β/IL-1RA ratio following GP + TSST-1 when compared to TSST-1.
T156 20887-21039 Sentence denotes Time course (48 h) of the IL-1β/IL-1RA ratio following incubation of human PBMC with LPS, TSST-1, GP + LPS, GP/LPS calc., GP + TSST-1 or GP/TSST-1 calc.
T157 21040-21125 Sentence denotes LPS and GP + LPS treatments resulted in generating more IL-1β than IL-1RA up to 24 h.
T158 21126-21249 Sentence denotes When comparing LPS or GP/LPS calc. vs GP + LPS we did not find significant alterations in the IL-1β/IL-1RA ratio over 48 h.
T159 21250-21500 Sentence denotes With respect to TSST-1 or GP/TSST-1 calc. vs GP + TSST-1 we observed a pronounced anti-inflammatory action of GP, as demonstrated by an about 10–100 fold reduced ratio at 18 h and 24 h, i.e. a higher production of IL-1RA than of IL-1β (* = p < 0.05).
T160 21501-21538 Sentence denotes Data are shown as mean ± SEM (n = 3).
T161 21540-21604 Sentence denotes Inhibition of transcription factors led to reduced IL-1RA levels
T162 21605-21767 Sentence denotes Pharmacological inhibitors were used to demonstrate that the transcription factor sites within the IL-1RA promoter are relevant for the induction of IL-1RA by GP.
T163 21768-22054 Sentence denotes As expected, an inhibition of NFκB via CAPE [35] and CyA, NFAT via CyA and NFIL-6 via CHX [36] could not be overruled by GP, leading to a down-regulated binding activity of the transcription factors to the IL-1RA sites, and a reduction of IL-1RA mRNA and IL-1RA protein levels (Fig. 7).
T164 22055-22217 Sentence denotes The extent of reduction in NFATP2/3 binding is exemplarily shown in an autoradiogram (Fig. 7A, left side) and graphically summarized (n = 4, Fig. 7A, right side).
T165 22218-22298 Sentence denotes The results for the NFκB and NFIL-6 binding sites were similar (data not shown).
T166 22299-22410 Sentence denotes Because the highest IL-1RA amount was found at 24 h, mRNA was examined following 1 h inhibition and 18 h of GP.
T167 22411-22544 Sentence denotes A representative gel demonstrating a decrease in IL-1RA mRNA after inhibition with CAPE, CyA and CHX is displayed in Fig. 7B (n = 4).
T168 22545-22640 Sentence denotes In addition, corresponding IL-1RA protein levels after 24 h of GP are shown in Fig. 7C (n = 3).
T169 22641-22805 Sentence denotes Altogether, NFκB inhibition by CAPE was more pronounced at the binding activity and the transcription, whereas CyA and CHX mainly led to a decreased IL-1RA release.
T170 22806-22898 Sentence denotes Figure 7 Inhibition of GP-induced NFκB, NFAT and NFIL-6 DNA binding to the IL-1RA promoter.
T171 22899-23274 Sentence denotes A, A representative autoradiogram (lane 1: control, lane 2: GP, lane 3: GP + unlabeled mutated NFATP2/3 oligo, lane 4: GP + CAPE, lane 5: GP + CyA, lane 6: GP + CHX, lane 7: GP + unlabeled NFATP2/3 oligo, lane 8: water) as well as a graphical summary for the NFATP2/3 site, depicting a decrease in binding following inhibition when compared to GP is displayed (* = p < 0.05).
T172 23275-23312 Sentence denotes Data are shown as mean ± SEM (n = 4).
T173 23313-23428 Sentence denotes B, Inhibition of NFκB, NFAT and NFIL-6 resulted in decreased IL-1RA mRNA following CHX, CAPE or CyA compared to GP.
T174 23429-23495 Sentence denotes GAPDH is used as housekeeping control (representative gel, n = 4).
T175 23496-23688 Sentence denotes C, Inhibition of NFκB, NFAT and NFIL-6 significantly reduced the production of IL-1RA by human PBMC following treatment with CHX, CAPE or CyA when compared to GP (* = p < 0.05; ** = p < 0.01).
T176 23689-23726 Sentence denotes Data are shown as mean ± SEM (n = 3).
T177 23728-23738 Sentence denotes Discussion
T178 23739-23923 Sentence denotes Animal models of sepsis and myocardial injury suggest that a β-1→3-D-glucan like GP mediates its protective mechanisms, in part, via a rapid shift from NFκB- to PI3K-signaling [22,37].
T179 23924-24145 Sentence denotes Our study provides novel evidence that downstream of recognition and signaling pro-inflammatory transcription factor binding and cytokine expression of human leukocytes is switched to an anti-inflammatory phenotype by GP.
T180 24146-24333 Sentence denotes We confirmed and extended previous results [13-16] indicating that, in the absence of other stimuli, β-1→3-D-glucans induced binding of NFκB-, NFIL-6- and NFAT-mers to cytokine promoters.
T181 24334-24536 Sentence denotes Because of the multiple band shifts observed for NFAT binding (Fig. 1A), one could speculate that there is activation of several different NFAT isoforms, probably derived from alternative splicing [38].
T182 24537-24685 Sentence denotes Interestingly, the GP-induced transcription factor binding transformed only into a very limited cytokine response, namely IL-8 and IL-1RA (Fig. 3B).
T183 24686-24820 Sentence denotes Hence, our data are in aggreement with the few reports describing a β-1→3-D-glucan-mediated IL-8 [6,16,19] and IL-1RA production [17].
T184 24821-25020 Sentence denotes In addition, our EMSA/supershift and immunoblotting results demonstrated a GP-mediated predominant binding of NFκB p65 and to a lesser extent of p50 to a κB consensus site of the IL-8 promoter (Figs.
T185 25021-25028 Sentence denotes 1A, 2).
T186 25029-25268 Sentence denotes Results by Schulte and colleagues [28] pointed to an induction of IL-8 transcription depending on activation via an NFκB p65/65 homodimer, rather than via p65/50 heterodimers, which might be the case for the GP-mediated IL-8 transcription.
T187 25269-25446 Sentence denotes A GP-mediated IL-8 transcription based upon a cooperation between transactivated NFκB p65 and NFIL-6 [13,39] or NFATc2 dimer binding to the IL-8κB site [38] seems also possible.
T188 25447-25756 Sentence denotes The IL-8κB consensus site exhibits a preferentially p65 binding half site and thus differs from the κB half site described for TNFα and IL-1β [27,40], supporting the idea of regulating NFκB binding through combinatorial associations of the subunits and the specific sequence of the decameric κB motif [41,42].
T189 25757-25908 Sentence denotes Unlike LPS or TSST-1, we found that GP did not induce IL-1β, but it strongly induced IL-1RA, suggesting an immediate anti-inflammatory potential of GP.
T190 25909-26156 Sentence denotes Analysing the IL-1RA promoter [34], we discovered four new binding sites (Fig. 8): an NFκB3 site (between -100 and -130), an NFκB consensus site (-266 and -280), another NFκB2/3 site (-288 and -302) and a more distal NFATP2/3 site (-471 and -490).
T191 26157-26437 Sentence denotes Our data indicated that GP leads to production of IL-1RA primarily via induction of NFATP2/3 and NFIL-6 DNA binding, which might be due to differences in the binding motif or the composition of the activated transcription factors (NFAT) between the IFNγ, IL-6 and IL-1RA promoter.
T192 26438-26724 Sentence denotes The differential decrease of NFκB, NFAT and NFIL-6 binding to sites in the IL-1RA promoter as well as of IL-1RA mRNA and protein induced by selective inhibitors prior to GP treatment might suggest that these steps are linked to each other and necessary for induction of IL-1RA (Fig. 7).
T193 26725-26834 Sentence denotes Regarding cellular sources, both, monocytes as well as neutrophils have been reported to produce IL-1RA [32].
T194 26835-26988 Sentence denotes Flow cytometric experiments seemed to confirm that monocytes and neutrophils were able to produce IL-8 just as IL-1RA in response to GP (data not shown).
T195 26989-27175 Sentence denotes This GP-induced cytokine profile was substantially more restricted than that of LPS or TSST-1, which is likely due to differences in recognition and signaling between LPS, TSST-1 and GP.
T196 27176-27357 Sentence denotes Recognition of LPS is mainly mediated through Toll-like receptor 4 and subsequent signaling via the NFκB pathway, leading to expression of pro-inflammatory mediators like TNFα [43].
T197 27358-27595 Sentence denotes A bacterial superantigen like TSST-1 acts through binding to MHC-II molecules and subsequently the T cell receptor, leading to release of mainly IFNγ and TNFα, the latter via both, PI3K and p38 mitogen-activated kinase signaling [44,45].
T198 27596-27824 Sentence denotes Altogether, the induction of the neutrophil-attracting IL-8 and the anti-inflammatory IL-1RA by fungal carbohydrates (GP) may well fit to a benign PAMP response, mounting defensive mechanisms against a possible microbial attack.
T199 27825-27886 Sentence denotes Figure 8 Cartoon of the sense strand of the IL-1RA promoter.
T200 27887-28065 Sentence denotes Relative locations of previously (LRE-1) [30-33] and newly described (boxed), positively (black) and negatively (gray) regulatory transcription factor binding sites are depicted.
T201 28066-28341 Sentence denotes Potentially even more relevant than the specific cytokine panel induced by GP, we found that, in the presence of other stimuli (LPS or TSST-1), GP ameliorated their pro-inflammatory immune reactions, similar to the effects in murine models of sepsis and inflammation [21-24].
T202 28342-28547 Sentence denotes Mainly, GP altered the TSST-1-induced IL-1β/IL-1RA ratio from a pro- to an anti-inflammatory profile via down-regulation of IL-1β and IL-6, at the same time there was a synergistic up-regulation of IL-1RA.
T203 28548-28788 Sentence denotes In part, this change may be caused by GP-mediated modulations of the TSST-1 induced binding of NFκB, NFIL-6 and NFAT to known and up to now unknown sites within the IL-8 and IL-1RA promoter instead of the TNFα, IL-1β, IL-6 or IFNγ promoter.
T204 28789-29026 Sentence denotes Accordingly, we found that the TSST-1-induced binding of NFκB to sites from the TNFα promoter negatively correlated with the GP-mediated enhancement of the TSST-1-induced IL-1RA production (r = -0.88; p < 0.01; data not shown in detail).
T205 29027-29232 Sentence denotes Of the four examined NFκB sites from the IL-1RA promoter, mostly the TSST-1- and LPS-induced binding to the NFκB3 and the TSST-1-induced binding to the new NFκB consensus site seemed to be increased by GP.
T206 29233-29448 Sentence denotes So, while we observed a GP-mediated down-regulation of the LPS- and the TSST-1-induced NFκB binding to sites of the TNFα promoter, there was an up-regulation to NFκB3 and NFκB consensus sites of the IL-1RA promoter.
T207 29449-29830 Sentence denotes These seemingly contradictory data could be explained by differences in either NFκB subunits or conserved nucleotides (#1, 2, 3, 10) within the decameric NFκB binding motif between the TNFα and the IL-1RA promoter (for NFκB3 the IL-1RA motif contains a T on position 10 instead of the conserved C in the TNFα motif, see Table 1), probably leading to differences in binding [41,42].
T208 29831-29996 Sentence denotes Despite the location of the new NFκB consensus site (-266 and -280) in the inhibitory element (-250 and -294) of the IL-1RA promoter [30], we observed no inhibition.
T209 29997-30215 Sentence denotes On the other side, we found an inhibitory NFκB2/3 site (-288 and -302) towards the end of the inhibitory element, demonstrating down-regulations of the LPS- and TSST-1-induced binding, which could not be altered by GP.
T210 30216-30334 Sentence denotes In our opinion, this site may therefore represent at least a part of the previoulsy described inhibitory element [30].
T211 30335-30570 Sentence denotes The GP-modulated increase in TSST-1-induced binding to the new NFκB3 and NFκB consensus site, the NFIL-6 site [32] as well as to the novel NFATP2/3 site may explain the synergistic up-regulation of the TSST-1-induced IL-1RA production.
T212 30571-30718 Sentence denotes We think that this GP-modulated activation of transcription was reflected by the decrease of the IL-1β/IL-1RA ratio following GP + TSST-1 (Fig. 6).
T213 30719-30864 Sentence denotes In this context, it has been postulated that in vitro a 100fold excess of IL-1RA over IL-1β might control the biological effects of IL-1 [46,47].
T214 30865-31040 Sentence denotes Since, in fact, the IL-1β/IL-1RA ratio following GP + TSST-1 is partially less than 0.01, it is not unreasonable to assume that IL-1β bioactivity is inactivated in our system.
T215 31041-31159 Sentence denotes Indeed, GP reduced the TSST-1-induced, IL-1-dependent IL-2 production of murine EL-4 cells (data not shown in detail).
T216 31160-31361 Sentence denotes The weaker modulating effects of GP on the LPS-induced immune response observed in this study, may be attributed to delicately balanced differences in signaling pathways between LPS and TSST-1 [43-45].
T217 31362-31484 Sentence denotes TSST-1 has been shown to use the PI3K pathway for signaling [44] and this effect may be sustained by GP treatment [22,37].
T218 31485-31624 Sentence denotes It has been demonstrated that in septic/LPS-adapted leukocytes the PI3K pathway selectively controls sIL-1RA but not IL-1β production [48].
T219 31625-31719 Sentence denotes Signaling via PI3K has been reported to be involved in the activation of NFAT in T cells [49].
T220 31720-31898 Sentence denotes Activation of NFκB can also take place via PI3K [50], which may offer an explanation for a difference in signaling between GP (PI3K) and LPS (mitogen-activated kinase signaling).
T221 31899-32193 Sentence denotes This idea may be supported by another study showing that despite the use of similar PRR, LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins and acted synergistically in combination, suggestive of signals which are not equivalent in all parts [51].
T222 32195-32205 Sentence denotes Conclusion
T223 32206-32500 Sentence denotes In summary, our data demonstrated that in vitro glucan phosphate induced a transcription factor binding and a subsequent cytokine profile different from LPS and also from TSST-1 and, moreover, switched a pro-inflammatory TSST-1-induced response to an IL-1RA-mediated anti-inflammatory reaction.
T224 32501-32743 Sentence denotes Our results also generated new insights into a very complex interplay of transcription factor binding to various known and newly identified sites in the IL-1RA promoter (Fig. 8), which can be regulated differentially by a fungal carbohydrate.
T225 32744-32967 Sentence denotes Together with the in vivo studies [22,37], our findings might support the concept of protective effects mediated by glucan phosphate in pro-inflammatory conditions, especially with a dysregulated IL-1β/IL-1RA ratio [52,53].
T226 32969-32976 Sentence denotes Methods
T227 32978-32987 Sentence denotes Materials
T228 32988-33070 Sentence denotes Water soluble phosphorylated β-1→3-D-glucan (GP) was prepared as done before [20].
T229 33071-33160 Sentence denotes The physicochemical characteristics of GP were determined as reported previously [20,26].
T230 33161-33388 Sentence denotes GP was dissolved in aqueous media, filter-sterilized (0.2 μm) and screened for endotoxin contamination with the Endospecy assay (Seigakaku, Tokyo, Japan), which is specific for endotoxin but does not respond to β-1→3-D-glucans.
T231 33390-33413 Sentence denotes Isolation of human PBMC
T232 33414-33585 Sentence denotes Buffy coats were obtained from healthy blood donors in compliance with the Helsinki declaration and with the approval of the ethics committee of the University of Luebeck.
T233 33586-33684 Sentence denotes The buffy coats were separated over a Ficoll-Hypaque (Biochrom, Berlin, Germany) gradient [54,55].
T234 33685-34131 Sentence denotes Following isolation, PBMC were cultured at a final concentration of 3 × 106 cells/ml (for ELISA measurements) or 5 × 106/ml (for gel shifts) or 1 × 106 cells/ml (for flow cytometry) in RPMI 1640 medium (BioWhittaker, Heidelberg, Germany, LPS-free), containing 10% heat-inactivated fetal calf serum (FCS, low-LPS, Invitrogen, Karlsruhe, Germany), 1% penicillin (10000 U/ml), 1% streptomycin (10000 μg/ml), and 1% 200 mM L-glutamine (BioWhittaker).
T235 34133-34155 Sentence denotes Stimulation conditions
T236 34156-34325 Sentence denotes For induction of transcription factors and cytokines, PBMC were cultured in a volume of 4 ml in sterile pyrogen-free 6-well culture plates (Falcon, Heidelberg, Germany).
T237 34326-34604 Sentence denotes Cultures were stimulated for 1 h (EMSA) or from 0 h to 48 h (ELISA) with 1 or 100 μg per 106 cells of GP, with 250 ng/106 cells TSST-1 (Toxin Technologies, Sarasota, FL, USA) or with 250 ng/106 cells wild-type LPS from Escherichia coli serotype 0111:B4 (Sigma, Munich, Germany).
T238 34605-34745 Sentence denotes In costimulatory experiments, PBMC were supplemented simultaneously with a combination of GP and TSST-1 or with a combination of GP and LPS.
T239 34747-34793 Sentence denotes Oligonucleotides (Oligos) and 5'-32-P-Labeling
T240 34794-35228 Sentence denotes The complementary double-stranded (ds) oligonucleotides (oligos) from the TNFα, IL-8, IFNγ and IL-6 promoters were synthesised from single stranded (ss) oligos (illustrated in Table 1), (TIB Molbiol, Berlin, Germany) and 32P-labeled with 5'γ-P-ATP (3,000 Ci/mmol, Amersham, Braunschweig, Germany) using the Ready-To-Go-Polynucleotide-Kinase Kit (PNK Kit, Pharmacia LKB, Freiburg, Germany) according to the manufacturer's instructions.
T241 35229-35326 Sentence denotes To test the binding specificity of the oligos, mutated oligos were used as an additional control.
T242 35327-35565 Sentence denotes Mutations in the P2 site of the IFNγ promoter [29] and in the κ consensus sequence of the TNFα promoter [55] have been reported to interfere with sequences, which seem to be crucial for the binding of NFAT and NFκB proteins, respectively.
T243 35566-35719 Sentence denotes Afterwards, the ds oligos were purified via gel filtration using Probe Quant G-50 Micro Columns (Pharmacia) according to the manufacturer's instructions.
T244 35721-35801 Sentence denotes Preparation of nuclear extracts and electrophoretic mobility shift assays (EMSA)
T245 35802-35952 Sentence denotes Nuclear extracts of purified PBMCs were prepared according to a technique described by Trede et al. [27] and modified for our experimental setup [56].
T246 35953-36033 Sentence denotes The intensity of shifted bands was normalized to bands of unstimulated controls.
T247 36034-36229 Sentence denotes Competition experiments with labeled and unlabeled mutated oligos of the cytokine promoter binding sites (see above) were carried out in order to prevent non-specific binding to nuclear proteins.
T248 36230-36324 Sentence denotes For such experiments, an excess (5–50×) of unlabeled oligos was added to the nuclear extracts.
T249 36325-36444 Sentence denotes For specificity of binding, supershift assays for NFκB with a combined p65/50 antibody were performed (data not shown).
T250 36445-36595 Sentence denotes To exclude non-specific reactions, a 30-fold molar excess of Oct-1 DNA (unrelated DNA, Table 1) was used, which did not compete with specific binding.
T251 36597-36614 Sentence denotes Immuno (Dot) blot
T252 36615-37422 Sentence denotes To determine whether the DNA binding proteins were related to NFκB and NFAT, dot blots using a SRC96D SNS minifold I dot blotter (Schleicher & Schüll, Dassel, Germany) were performed with the following positive controls and antibodies (all from Santa Cruz Biotechnology, Heidelberg, Germany): positive controls (10 ng/dot): NFκB p52 (80 kD) sc-4095WB, c-Rel (61 kD) sc-4030WB; Jurkat nuclear extract, PMA-stimulated; primary antibodies (1 μg/dot): anti-NFκB p50 (NLS) sc-114, anti-NFκB p65 (A) sc-109, anti-NFκB p52 (447) sc-848, a rabbit polyclonal IgG1 antiserum, anti-c-rel (N466) sc-272, anti-NFATc2 (M-20) sc-1151, anti-NFATc1 (K-18) sc-1149, two goat polyclonal IgG1 antisera; secondary antibodies (0.8 μg/dot): goat anti-rabbit IgG AP-conjugate sc-2007, and donkey anti-goat IgG AP-conjugate sc-2022.
T253 37423-37498 Sentence denotes The nuclear proteins were blotted onto a nitrocellulose membrane (Bio-Rad).
T254 37499-37761 Sentence denotes After blocking with PBS/3% BSA (Fluka, Deisenhofen, Germany), the blot was incubated overnight with the primary antibodies diluted 1:2000 in PBS/1% BSA, washed again and incubated with the alkaline phosphatase-conjugated secondary antibody (1:500 in PBS/1% BSA).
T255 37762-37845 Sentence denotes The blot was developed using the Vectastain® staining kit (Vector Laboratories Inc.
T256 37846-37867 Sentence denotes Burlingame, CA, USA).
T257 37869-37890 Sentence denotes Cytokine measurements
T258 37891-38048 Sentence denotes Supernatants of cell cultures were harvested 3, 6, 9, 12, 18, 24, 30, 36 and 48 hours after stimulation and stored at -80 °C until used and thawed only once.
T259 38049-38279 Sentence denotes IFNγ, TNFα, IL-1 and IL-6 were determined using an ELISA from Bender Systems (Vienna, Austria), IL-1RA and IL-8 by an ELISA from R&D Systems (Wiesbaden-Nordenstadt, Germany), and TGFβ 1 using an ELISA as previously described [57].
T260 38280-38385 Sentence denotes Quantification of IL-2 as an indicator for the bioactivity of IL-1 was done as previously described [46].
T261 38386-38457 Sentence denotes Samples were diluted in the same buffer as that used for the standards.
T262 38458-38581 Sentence denotes All cytokines were quantified using an ELISA plate reader (Anthos Labotec, Salzburg, Austria or Microplate Reader, BioRad).
T263 38582-38647 Sentence denotes Cytokine amounts were all within the range of the standard curve.
T264 38648-38763 Sentence denotes Only stimulation of PBMC observed in donors showing no spontaneous cytokine release was included in the statistics.
T265 38765-38800 Sentence denotes Inhibition of transcription factors
T266 38801-39001 Sentence denotes To inhibit translocation and binding of transcription factors to the IL-1RA promoter, PBMC were incubated for 1 h with each of the following substances (concentrations were based upon 50% inhibition):
T267 39002-39252 Sentence denotes 50 μg/ml of CAPE (caffeic-3,4-dihydroxycinnamic-acid-phenyl-ester), (Biomol, Hamburg, Germany); 400 ng/ml cyclosporin A (Calbiochem-Merck Biosciences, Bad Soden, Germany); 10 μg/ml cycloheximide (Santa Cruz Biotechnology) prior to incubation with GP.
T268 39253-39505 Sentence denotes Band shifts were determined after 1 h incubation with GP as described before, including mutated oligos for NFIL-6 (TTA CAA CAG TGG ATT GCG ACA CTT AGT GGG) and NFATP2/3 (GGC GCA GAA AAG GTA AAA TAT TTA CTA TCT) binding sites within the IL-1RA promoter.
T269 39506-39931 Sentence denotes PBMC RNA was isolated with an RNeasy kit (Qiagen, Germany) and messenger RNA was transcribed into cDNA with Reactin Ready First Strand kit (Biomol) and analysed for IL-1RA and GAPDH transcripts by PCR with a HotStart "sweet" PCR mastermix (Biomol) (95°C, 30 sec, 55°C, 30 sec, 72°C, 30 sec, 25 cycles for IL-1RA and 94°C for 30 sec, 50°C for 30 sec and 72°C for 45 sec, 25 cycles for GAPDH) following 18 h incubation with GP.
T270 39932-40018 Sentence denotes IL-1RA protein was measured in the supernatant by ELISA after 24 h incubation with GP.
T271 40020-40040 Sentence denotes Statistical analysis
T272 40041-40190 Sentence denotes The Kolmogorow-Smirnov test was used to evaluate, whether cytokine amounts and binding activities to transcription factors were normally distributed.
T273 40191-40351 Sentence denotes Correlation coefficients and corresponding significances were analyzed by the Pearson test (normal distribution) or the Spearman test (non-normal distribution).
T274 40352-40549 Sentence denotes To compare experimental data to a theoretical value (for example GP + TSST-1 vs GP/TSST-1 calc.) we calculated the sum of the individual effects and added these values into Fig. 1B, 3, 4, 5, and 6.
T275 40550-40917 Sentence denotes Significances of differences between experimental data (for example GP vs LPS) as well as between experimental data and theoretical values (for example GP + TSST-1 vs GP/TSST-1 calc.) were analysed using the Student's t-test (normal distribution) or the Wilcoxon Signed-Rank test (non-normal distribution), (SPSS for Windows; SPSS Science Software, Erkrath, Germany).
T276 40919-40932 Sentence denotes Abbreviations
T277 40933-41388 Sentence denotes LPS, lipopolysaccharide; TSST-1, toxic shock syndrome toxin 1; GP, glucan phosphate; PBMC, peripheral blood mononuclear cells; PMN, polymorphonuclear neutrophils; LRE, LPS-responsive element; NF, nuclear factor; IL, interleukin; BSA, bovine serum albumin; PBS, phosphate buffered saline; PMA, phorbol myristate acetate; ATP, adenosine triphosphate; SEM, standard error of the mean; n.s., non-significant (p > 0.05); CyA, cyclosporin A; CHX, cycloheximide.
T278 41390-41412 Sentence denotes Authors' contributions
T279 41413-41561 Sentence denotes JL participated in the study design and coordination, developed the band shifts assays, performed the statistics and helped to draft the manuscript.
T280 41562-41613 Sentence denotes UL carried out band shift assays and the dot blots.
T281 41614-41705 Sentence denotes JH, CF and JMB carried out band shift assays and participated in the ELISA and PCR studies.
T282 41706-41769 Sentence denotes HH designed the oligos for the analysis of the IL-1RA promoter.
T283 41770-41809 Sentence denotes LR participated in the PCR experiments.
T284 41810-41874 Sentence denotes PK performed the ELISA tests and the flow cytometry experiments.
T285 41875-41924 Sentence denotes NW carried out the IL-1RA inhibition experiments.
T286 41925-41986 Sentence denotes DLW conceived of the study and prepared the glucan phosphate.
T287 41987-42091 Sentence denotes AM conceived of the study, participated in the study design and coordination and drafted the manuscript.
T288 42092-42143 Sentence denotes All authors read and approved the final manuscript.

ICD10

Id Subject Object Predicate Lexical cue
T333 572-592 http://purl.bioontology.org/ontology/ICD10/A48.3 denotes toxic shock syndrome
T334 578-583 http://purl.bioontology.org/ontology/ICD10/R57.9 denotes shock
T17621 33453-33465 http://purl.bioontology.org/ontology/ICD10/Z52.0 denotes blood donors
T17465 33203-33213 http://purl.bioontology.org/ontology/ICD10/Z30.2 denotes sterilized
T12518 23778-23784 http://purl.bioontology.org/ontology/ICD10/T14.9 denotes injury

simple1

Id Subject Object Predicate Lexical cue
T26191 27870-27876 Protein denotes IL-1RA
T25593 23575-23581 Protein denotes IL-1RA
T25592 23528-23534 Protein denotes NFIL-6
T25591 23519-23523 Protein denotes NFAT
T25590 23429-23434 Protein denotes GAPDH
T25589 23374-23380 Protein denotes IL-1RA
T25588 23345-23351 Protein denotes NFIL-6
T25587 23336-23340 Protein denotes NFAT
T25586 22882-22888 Protein denotes IL-1RA
T25585 22856-22862 Protein denotes NFIL-6
T25584 22847-22851 Protein denotes NFAT
T24923 21479-21484 Protein denotes IL-1β
T24922 21464-21470 Protein denotes IL-1RA
T24921 21300-21306 Protein denotes TSST-1
T24920 21279-21285 Protein denotes TSST-1
T24919 21266-21272 Protein denotes TSST-1
T24918 21226-21232 Protein denotes IL-1RA
T24917 21220-21225 Protein denotes IL-1β
T24916 21107-21113 Protein denotes IL-1RA
T24915 21096-21101 Protein denotes IL-1β
T24914 21027-21033 Protein denotes TSST-1
T24913 21014-21020 Protein denotes TSST-1
T24912 20977-20983 Protein denotes TSST-1
T24911 20919-20925 Protein denotes IL-1RA
T24910 20913-20918 Protein denotes IL-1β
T24909 20879-20885 Protein denotes TSST-1
T24908 20855-20861 Protein denotes TSST-1
T24907 20827-20833 Protein denotes IL-1RA
T24906 20821-20826 Protein denotes IL-1β
T23907 18710-18716 Protein denotes TSST-1
T23906 18679-18685 Protein denotes TSST-1
T23905 18649-18655 Protein denotes TSST-1
T23904 18589-18595 Protein denotes IL-1RA
T23903 18539-18545 Protein denotes TSST-1
T24265 19648-19654 Protein denotes TSST-1
T24264 19609-19615 Protein denotes TSST-1
T24263 19379-19385 Protein denotes TSST-1
T24262 19300-19306 Protein denotes IL-1RA
T24261 19255-19259 Protein denotes NFAT
T24260 19177-19183 Protein denotes TSST-1
T24259 19160-19166 Protein denotes TSST-1
T24258 19085-19091 Protein denotes TSST-1
T24257 19017-19023 Protein denotes TSST-1
T24256 18953-18959 Protein denotes IL-1RA
T24255 18896-18902 Protein denotes TSST-1
T23077 13297-13303 Protein denotes IL-1RA
T23076 13270-13276 Protein denotes TSST-1
T23075 13176-13182 Protein denotes TSST-1
T23074 13104-13110 Protein denotes IL-1RA
T23073 13054-13060 Protein denotes TSST-1
T23072 12956-12962 Protein denotes TSST-1
T23071 12943-12949 Protein denotes TSST-1
T23070 12854-12860 Protein denotes IL-1RA
T23069 12824-12830 Protein denotes TSST-1
T23068 12786-12792 Protein denotes TSST-1
T23067 12748-12754 Protein denotes IL-1RA
T23066 12652-12657 Protein denotes IL-1β
T23065 12623-12629 Protein denotes TSST-1
T23064 12536-12542 Protein denotes TSST-1
T23063 12512-12518 Protein denotes TSST-1
T23062 12480-12485 Protein denotes IL-1β
T23061 12398-12404 Protein denotes TSST-1
T23060 12385-12391 Protein denotes TSST-1
T23059 12297-12302 Protein denotes IL-1β
T23058 12267-12273 Protein denotes TSST-1
T23057 12243-12249 Protein denotes TSST-1
T23056 12189-12194 Protein denotes IL-1β
T22469 10740-10742 Protein denotes c1
T22468 10731-10738 Protein denotes NFAT c2
T22467 10723-10726 Protein denotes p50
T22466 10718-10721 Protein denotes p65
T22465 10624-10626 Protein denotes c2
T22464 10616-10622 Protein denotes NFATc1
T22463 10604-10607 Protein denotes p65
T22462 10599-10602 Protein denotes p50
T22461 10529-10534 Protein denotes c-rel
T22460 10524-10527 Protein denotes p52
T22459 10379-10383 Protein denotes NFAT
T22458 10239-10241 Protein denotes c1
T22456 10224-10227 Protein denotes p50
T22455 10220-10223 Protein denotes p65
T21594 9947-9953 Protein denotes TSST-1
T21593 9765-9771 Protein denotes TSST-1
T21592 9739-9745 Protein denotes TSST-1
T21591 9676-9682 Protein denotes TSST-1
T21590 9661-9667 Protein denotes TSST-1
T21589 9641-9647 Protein denotes TSST-1
T21588 9506-9509 Protein denotes p50
T21587 9497-9500 Protein denotes p65
T21586 9483-9487 Protein denotes IL-8
T21585 9375-9379 Protein denotes IL-8
T21584 9356-9362 Protein denotes NFIL-6
T21583 9336-9340 Protein denotes NFAT
T21582 9241-9245 Protein denotes IL-8
T21581 9232-9236 Protein denotes IL-6
T21580 9226-9230 Protein denotes TNFα
T21579 9220-9224 Protein denotes IFNγ
T21578 9172-9176 Protein denotes IL-8
T21577 9157-9163 Protein denotes NFIL-6
T21576 9145-9149 Protein denotes NFAT
T21575 9002-9008 Protein denotes NFIL-6
T21574 8987-8991 Protein denotes NFAT
T20331 39932-39938 Protein denotes IL-1RA
T20330 39682-39687 Protein denotes GAPDH
T20329 39671-39677 Protein denotes IL-1RA
T20328 39489-39495 Protein denotes IL-1RA
T20327 39420-39421 Protein denotes 3
T20326 39413-39419 Protein denotes NFATP2
T20325 39360-39366 Protein denotes NFIL-6
T20324 38870-38876 Protein denotes IL-1RA
T19800 38342-38346 Protein denotes IL-1
T19799 38298-38302 Protein denotes IL-2
T19798 38228-38234 Protein denotes TGFβ 1
T19797 38156-38160 Protein denotes IL-8
T19796 38145-38151 Protein denotes IL-1RA
T19795 38070-38074 Protein denotes IL-6
T19794 38061-38065 Protein denotes IL-1
T19793 38055-38059 Protein denotes TNFα
T19792 38049-38053 Protein denotes IFNγ
T19274 37240-37246 Protein denotes NFATc1
T19273 37212-37218 Protein denotes NFATc2
T19272 37186-37191 Protein denotes c-rel
T19271 37127-37130 Protein denotes p52
T19270 37101-37104 Protein denotes p65
T19269 37073-37076 Protein denotes p50
T19268 36967-36972 Protein denotes c-Rel
T19267 36944-36947 Protein denotes p52
T19266 36686-36690 Protein denotes NFAT
T18302 35528-35532 Protein denotes NFAT
T18301 35417-35421 Protein denotes TNFα
T18300 35359-35363 Protein denotes IFNγ
T18299 34889-34893 Protein denotes IL-6
T18298 34880-34884 Protein denotes IFNγ
T18297 34874-34878 Protein denotes IL-8
T18296 34868-34872 Protein denotes TNFα
T17132 32946-32952 Protein denotes IL-1RA
T17131 32940-32945 Protein denotes IL-1β
T17130 32654-32660 Protein denotes IL-1RA
T17129 32457-32463 Protein denotes IL-1RA
T17128 32427-32433 Protein denotes TSST-1
T17127 32377-32383 Protein denotes TSST-1
T12721 26473-26477 Protein denotes NFAT
T12720 26421-26427 Protein denotes IL-1RA
T12719 26412-26416 Protein denotes IL-6
T12718 26406-26410 Protein denotes IFNγ
T12717 26388-26392 Protein denotes NFAT
T12716 26254-26260 Protein denotes NFIL-6
T12715 26248-26249 Protein denotes 3
T12714 26241-26247 Protein denotes NFATP2
T12713 25923-25929 Protein denotes IL-1RA
T12712 25842-25848 Protein denotes IL-1RA
T12711 25811-25816 Protein denotes IL-1β
T12710 25771-25777 Protein denotes TSST-1
T12709 25583-25588 Protein denotes IL-1β
T12708 25574-25578 Protein denotes TNFα
T12707 25499-25502 Protein denotes p65
T12706 25451-25455 Protein denotes IL-8
T12705 25409-25413 Protein denotes IL-8
T12704 25381-25387 Protein denotes NFATc2
T12703 25363-25369 Protein denotes NFIL-6
T12702 25355-25358 Protein denotes p65
T12701 25283-25287 Protein denotes IL-8
T12700 25249-25253 Protein denotes IL-8
T12699 25188-25190 Protein denotes 50
T12698 25184-25187 Protein denotes p65
T12697 25154-25156 Protein denotes 65
T12696 25150-25153 Protein denotes p65
T12695 25095-25099 Protein denotes IL-8
T12694 25000-25004 Protein denotes IL-8
T12693 24966-24969 Protein denotes p50
T12692 24936-24939 Protein denotes p65
T12691 24797-24803 Protein denotes IL-1RA
T12690 24778-24782 Protein denotes IL-8
T12689 24668-24674 Protein denotes IL-1RA
T12688 24659-24663 Protein denotes IL-8
T12687 24473-24477 Protein denotes NFAT
T12686 24383-24387 Protein denotes NFAT
T12685 24301-24305 Protein denotes NFAT
T12684 24289-24295 Protein denotes NFIL-6
T12790 32024-32030 Protein denotes IL-1RA
T12789 31698-31702 Protein denotes NFAT
T12788 31602-31607 Protein denotes IL-1β
T12787 31587-31593 Protein denotes IL-1RA
T12786 31362-31368 Protein denotes TSST-1
T12785 31346-31352 Protein denotes TSST-1
T12784 31095-31099 Protein denotes IL-2
T12783 31080-31084 Protein denotes IL-1
T12782 31064-31070 Protein denotes TSST-1
T12781 30993-30998 Protein denotes IL-1β
T12780 30919-30925 Protein denotes TSST-1
T12779 30891-30897 Protein denotes IL-1RA
T12778 30885-30890 Protein denotes IL-1β
T12777 30851-30855 Protein denotes IL-1
T12776 30805-30810 Protein denotes IL-1β
T12775 30793-30799 Protein denotes IL-1RA
T12774 30702-30708 Protein denotes TSST-1
T12773 30674-30680 Protein denotes IL-1RA
T12772 30668-30673 Protein denotes IL-1β
T12771 30552-30558 Protein denotes IL-1RA
T12770 30537-30543 Protein denotes TSST-1
T12769 30364-30370 Protein denotes TSST-1
T12768 30158-30164 Protein denotes TSST-1
T12767 29948-29954 Protein denotes IL-1RA
T12766 29647-29653 Protein denotes IL-1RA
T12765 29634-29638 Protein denotes TNFα
T12764 29432-29438 Protein denotes IL-1RA
T12763 29349-29353 Protein denotes TNFα
T12762 29305-29311 Protein denotes TSST-1
T12761 29149-29155 Protein denotes TSST-1
T12760 29096-29102 Protein denotes TSST-1
T12759 29068-29074 Protein denotes IL-1RA
T12758 28960-28966 Protein denotes IL-1RA
T12757 28945-28951 Protein denotes TSST-1
T12756 28869-28873 Protein denotes TNFα
T12755 28820-28826 Protein denotes TSST-1
T12754 28774-28778 Protein denotes IFNγ
T12753 28766-28770 Protein denotes IL-6
T12752 28759-28764 Protein denotes IL-1β
T12751 28753-28757 Protein denotes TNFα
T12750 28722-28728 Protein denotes IL-1RA
T12749 28713-28717 Protein denotes IL-8
T12748 28660-28664 Protein denotes NFAT
T12747 28649-28655 Protein denotes NFIL-6
T12746 28617-28623 Protein denotes TSST-1
T12745 28540-28546 Protein denotes IL-1RA
T12744 28476-28480 Protein denotes IL-6
T12743 28466-28471 Protein denotes IL-1β
T12742 28386-28392 Protein denotes IL-1RA
T12741 28380-28385 Protein denotes IL-1β
T12740 28365-28371 Protein denotes TSST-1
T12739 28201-28207 Protein denotes TSST-1
T12738 27682-27688 Protein denotes IL-1RA
T12737 27651-27655 Protein denotes IL-8
T12736 27548-27576 Protein denotes p38 mitogen-activated kinase
T12735 27512-27516 Protein denotes TNFα
T12734 27503-27507 Protein denotes IFNγ
T12733 27388-27394 Protein denotes TSST-1
T12732 27347-27351 Protein denotes TNFα
T12731 27222-27242 Protein denotes Toll-like receptor 4
T12730 27161-27167 Protein denotes TSST-1
T12729 27076-27082 Protein denotes TSST-1
T12728 26946-26952 Protein denotes IL-1RA
T12727 26933-26937 Protein denotes IL-8
T12726 26822-26828 Protein denotes IL-1RA
T12725 26708-26714 Protein denotes IL-1RA
T12724 26543-26549 Protein denotes IL-1RA
T12723 26513-26519 Protein denotes IL-1RA
T12722 26482-26488 Protein denotes NFIL-6
T10535 22790-22796 Protein denotes IL-1RA
T10534 22572-22578 Protein denotes IL-1RA
T10533 22460-22466 Protein denotes IL-1RA
T10532 22319-22325 Protein denotes IL-1RA
T10531 22023-22029 Protein denotes IL-1RA
T10530 22007-22013 Protein denotes IL-1RA
T10529 21974-21980 Protein denotes IL-1RA
T10528 21843-21849 Protein denotes NFIL-6
T10527 21826-21830 Protein denotes NFAT
T10526 21754-21760 Protein denotes IL-1RA
T10525 21704-21710 Protein denotes IL-1RA
T10524 21591-21597 Protein denotes IL-1RA
T9644 20743-20749 Protein denotes TSST-1
T9643 20730-20736 Protein denotes TSST-1
T9642 20706-20712 Protein denotes TSST-1
T9641 20663-20667 Protein denotes IL-2
T9640 20637-20641 Protein denotes IL-1
T9639 20526-20531 Protein denotes IL-1β
T9638 20511-20517 Protein denotes IL-1RA
T9637 20332-20338 Protein denotes TSST-1
T9636 20310-20316 Protein denotes TSST-1
T9635 20272-20278 Protein denotes TSST-1
T9634 20186-20192 Protein denotes IL-1RA
T9633 20180-20185 Protein denotes IL-1β
T9632 20032-20038 Protein denotes IL-1RA
T9631 20021-20026 Protein denotes IL-1β
T9630 19899-19905 Protein denotes IL-1RA
T9629 19893-19898 Protein denotes IL-1β
T8172 18336-18342 Protein denotes TSST-1
T8171 18301-18307 Protein denotes TSST-1
T8170 17906-17912 Protein denotes TSST-1
T8169 17832-17838 Protein denotes TSST-1
T8168 17468-17474 Protein denotes TSST-1
T8167 17423-17429 Protein denotes TSST-1
T8166 17291-17297 Protein denotes TSST-1
T8165 17230-17236 Protein denotes TSST-1
T8164 17096-17102 Protein denotes TSST-1
T8163 17000-17006 Protein denotes TSST-1
T8162 16620-16626 Protein denotes IL-1RA
T8161 16503-16509 Protein denotes IL-1RA
T8160 16413-16417 Protein denotes IFNγ
T8159 16405-16409 Protein denotes IL-6
T8158 16399-16403 Protein denotes TNFα
T8157 16297-16303 Protein denotes IL-1RA
T8156 16282-16288 Protein denotes TSST-1
T8155 16249-16255 Protein denotes TSST-1
T8154 16227-16231 Protein denotes NFAT
T8153 16216-16222 Protein denotes NFIL-6
T5172 16160-16166 Protein denotes TSST-1
T5171 16147-16153 Protein denotes TSST-1
T5170 16103-16109 Protein denotes TSST-1
T5169 16001-16007 Protein denotes TGFβ 1
T5168 15991-15996 Protein denotes IL-10
T5167 15985-15989 Protein denotes IL-4
T5166 15978-15983 Protein denotes IL-12
T5165 15972-15976 Protein denotes IL-2
T5164 15948-15953 Protein denotes TGFβ1
T5163 15941-15946 Protein denotes IL-10
T5162 15935-15939 Protein denotes IL-4
T5161 15928-15933 Protein denotes IL-12
T5160 15922-15926 Protein denotes IL-2
T5159 15884-15890 Protein denotes TSST-1
T5158 15871-15877 Protein denotes TSST-1
T5157 15829-15835 Protein denotes TSST-1
T5156 15703-15707 Protein denotes IFNγ
T5155 15598-15602 Protein denotes IFNγ
T5154 15590-15594 Protein denotes IFNγ
T5153 15449-15453 Protein denotes TNFα
T5152 15392-15398 Protein denotes TSST-1
T5151 15379-15385 Protein denotes TSST-1
T5150 15291-15295 Protein denotes TNFα
T5149 15142-15146 Protein denotes TNFα
T5148 15121-15125 Protein denotes TNFα
T5147 15044-15050 Protein denotes IL-1RA
T5146 15035-15039 Protein denotes IL-8
T5145 14924-14930 Protein denotes IL-1RA
T5144 14915-14919 Protein denotes IL-8
T5143 14814-14820 Protein denotes IL-1RA
T5142 14805-14809 Protein denotes IL-8
T5141 14725-14731 Protein denotes IL-1RA
T5140 14700-14706 Protein denotes TSST-1
T5139 14620-14626 Protein denotes TSST-1
T5138 14539-14545 Protein denotes TSST-1
T5137 14485-14491 Protein denotes IL-1RA
T5136 14443-14449 Protein denotes TSST-1
T5135 14400-14406 Protein denotes IL-1RA
T5134 14164-14170 Protein denotes IL-1RA
T5133 14158-14162 Protein denotes IL-8
T5132 14143-14149 Protein denotes IL-1RA
T5131 14096-14102 Protein denotes TSST-1
T5130 14083-14089 Protein denotes TSST-1
T5129 14059-14065 Protein denotes TSST-1
T5128 14028-14032 Protein denotes IL-8
T5127 13936-13940 Protein denotes IL-8
T5126 13775-13779 Protein denotes IL-8
T5125 13731-13735 Protein denotes IL-8
T5124 13626-13632 Protein denotes TSST-1
T5123 13613-13619 Protein denotes TSST-1
T5122 13589-13595 Protein denotes TSST-1
T5121 13564-13568 Protein denotes IL-6
T5120 13500-13504 Protein denotes IL-6
T5119 13436-13440 Protein denotes IL-6
T5118 13397-13401 Protein denotes IL-6
T5117 12146-12151 Protein denotes IL-1β
T5116 12121-12127 Protein denotes TSST-1
T5115 12039-12045 Protein denotes TSST-1
T5114 12001-12007 Protein denotes TSST-1
T5113 11932-11937 Protein denotes IL-1β
T5112 11889-11895 Protein denotes TSST-1
T5111 11813-11818 Protein denotes IL-1β
T5110 11704-11709 Protein denotes IL-1β
T5109 11685-11690 Protein denotes IL-1β
T5108 11671-11677 Protein denotes TSST-1
T5107 11095-11099 Protein denotes IFNγ
T5106 11089-11093 Protein denotes IL-6
T5105 11083-11087 Protein denotes IL-8
T5104 11077-11081 Protein denotes TNFα
T5103 10981-10985 Protein denotes IFNγ
T5102 10972-10976 Protein denotes IL-6
T5101 10966-10970 Protein denotes IL-8
T5100 10960-10964 Protein denotes TNFα
T5099 10891-10897 Protein denotes TSST-1
T5098 10861-10867 Protein denotes TSST-1
T392 69-73 Protein denotes IL-6
T393 119-124 Protein denotes IL-1β
T394 125-149 Protein denotes IL-1 receptor antagonist
T395 572-600 Protein denotes toxic shock syndrome toxin 1
T396 602-608 Protein denotes TSST-1
T397 668-687 Protein denotes NFinterleukin(IL)-6
T398 692-696 Protein denotes NFAT
T399 715-721 Protein denotes TSST-1
T400 764-769 Protein denotes IL-1β
T401 771-775 Protein denotes IL-6
T402 777-800 Protein denotes tumor necrosis factor α
T403 804-816 Protein denotes interferon γ
T404 914-918 Protein denotes IL-8
T405 1004-1008 Protein denotes IL-8
T406 1034-1057 Protein denotes IL-1receptor antagonist
T407 1058-1060 Protein denotes RA
T408 1162-1166 Protein denotes IL-8
T409 1274-1280 Protein denotes IL-1RA
T410 1385-1391 Protein denotes TSST-1
T411 1477-1483 Protein denotes TSST-1
T412 1513-1519 Protein denotes NFIL-6
T413 1524-1528 Protein denotes NFAT
T414 1567-1573 Protein denotes IL-1RA
T415 1615-1621 Protein denotes TSST-1
T416 1669-1674 Protein denotes IL-1β
T417 1679-1683 Protein denotes IL-6
T418 1732-1738 Protein denotes TSST-1
T419 1747-1752 Protein denotes IL-1β
T420 1753-1759 Protein denotes IL-1RA
T421 1851-1857 Protein denotes TSST-1
T422 1867-1871 Protein denotes IL-1
T423 1896-1900 Protein denotes IL-2
T424 2102-2108 Protein denotes IL-1RA
T425 2199-2205 Protein denotes IL-1RA
T3307 5877-5883 Protein denotes NFIL-6
T3308 5888-5892 Protein denotes NFAT
T3309 5916-5920 Protein denotes TNFα
T3310 5922-5926 Protein denotes IL-6
T3311 5931-5935 Protein denotes IFNγ
T3312 5996-6002 Protein denotes TSST-1
T3313 6026-6032 Protein denotes TSST-1
T3314 6098-6104 Protein denotes NFIL-6
T3315 6187-6191 Protein denotes TNFα
T3316 6223-6227 Protein denotes IL-8
T3317 6263-6267 Protein denotes IL-6
T3318 6397-6403 Protein denotes TSST-1
T3319 6475-6479 Protein denotes IL-8
T3320 6544-6547 Protein denotes p65
T3321 6574-6577 Protein denotes p50
T3322 6689-6692 Protein denotes p65
T3323 6718-6721 Protein denotes p50
T3324 6731-6734 Protein denotes p52
T3325 6863-6867 Protein denotes TNFα
T3326 6934-6940 Protein denotes TSST-1
T3327 6979-6985 Protein denotes TSST-1
T3328 7063-7069 Protein denotes TSST-1
T3329 7100-7106 Protein denotes TSST-1
T3330 7130-7136 Protein denotes TSST-1
T3331 7235-7239 Protein denotes NFAT
T3332 7261-7265 Protein denotes IFNγ
T3333 7308-7312 Protein denotes NFAT
T3334 7359-7365 Protein denotes NFATc2
T3335 7392-7398 Protein denotes NFATc1
T1258 3007-3015 Protein denotes Dectin-1
T9628 19784-19790 Protein denotes IL-1RA
T9627 19774-19779 Protein denotes IL-1β
T9626 19696-19702 Protein denotes IL-1RA
T9625 19690-19695 Protein denotes IL-1β
T9624 19675-19681 Protein denotes TSST-1
T1259 3042-3046 Protein denotes TNFα
T1260 3055-3075 Protein denotes Toll-like receptor 2
T22457 10232-10238 Protein denotes NFATc2
T21014 40720-40726 Protein denotes TSST-1
T21013 40707-40713 Protein denotes TSST-1
T21012 40435-40441 Protein denotes TSST-1
T21011 40422-40428 Protein denotes TSST-1
T18813 36506-36511 Protein denotes Oct-1
T18812 36400-36402 Protein denotes 50
T18811 36396-36399 Protein denotes p65
T17954 34702-34708 Protein denotes TSST-1
T17953 34454-34460 Protein denotes TSST-1
T1257 2732-2740 Protein denotes Dectin-1
T1261 3100-3105 Protein denotes MyD88
T1262 3202-3208 Protein denotes NFIL-6
T1263 3461-3465 Protein denotes IL-1
T1264 3467-3471 Protein denotes IL-6
T1265 3473-3477 Protein denotes TNFα
T1266 3549-3555 Protein denotes IL-1RA
T1267 3565-3569 Protein denotes IL-1
T1268 3771-3775 Protein denotes IL-8
T1269 4917-4923 Protein denotes TSST-1
T1270 5048-5052 Protein denotes TNFα
T1271 5054-5059 Protein denotes IL-1β
T1272 5061-5065 Protein denotes IL-6
T1273 5067-5071 Protein denotes IL-8
T1274 5076-5082 Protein denotes IL-1RA
T1275 5108-5112 Protein denotes IFNγ
T1276 5114-5118 Protein denotes IL-2
T1277 5120-5124 Protein denotes IL-4
T1278 5126-5131 Protein denotes IL-10
T1279 5133-5138 Protein denotes IL-12
T1280 5143-5148 Protein denotes TGFβ1
T1281 5192-5196 Protein denotes TNFα
T1282 5266-5270 Protein denotes IL-8
T1283 5308-5312 Protein denotes IFNγ
T1284 5371-5375 Protein denotes IL-6
T1285 5446-5452 Protein denotes IL-1RA
T1286 5508-5514 Protein denotes IL-1RA
T1287 5627-5633 Protein denotes IL-1RA
T1288 5822-5828 Protein denotes IL-1RA

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T26152 23549-23556 Negative_regulation denotes reduced
T26151 23561-23571 Gene_expression denotes production
T26150 23499-23509 Negative_regulation denotes Inhibition
T26149 23364-23373 Negative_regulation denotes decreased
T26148 23352-23360 Positive_regulation denotes resulted
T26147 22816-22826 Negative_regulation denotes Inhibition
T26146 22867-22874 Binding denotes binding
T26145 23528-23534 Protein denotes NFIL-6
T26144 23519-23523 Protein denotes NFAT
T26143 23575-23581 Protein denotes IL-1RA
T26142 23429-23434 Protein denotes GAPDH
T26141 23374-23380 Protein denotes IL-1RA
T26140 23345-23351 Protein denotes NFIL-6
T26139 23336-23340 Protein denotes NFAT
T26138 22882-22888 Protein denotes IL-1RA
T26137 22856-22862 Protein denotes NFIL-6
T26136 22847-22851 Protein denotes NFAT
T25414 21404-21411 Negative_regulation denotes reduced
T25413 21450-21460 Gene_expression denotes production
T25412 21068-21076 Positive_regulation denotes resulted
T25411 21080-21090 Positive_regulation denotes generating
T25410 20811-20820 Negative_regulation denotes Decreased
T25409 21479-21484 Protein denotes IL-1β
T25408 21464-21470 Protein denotes IL-1RA
T25407 21300-21306 Protein denotes TSST-1
T25406 21279-21285 Protein denotes TSST-1
T25405 21266-21272 Protein denotes TSST-1
T25404 21226-21232 Protein denotes IL-1RA
T25403 21220-21225 Protein denotes IL-1β
T25402 21107-21113 Protein denotes IL-1RA
T25401 21096-21101 Protein denotes IL-1β
T25400 21027-21033 Protein denotes TSST-1
T25399 21014-21020 Protein denotes TSST-1
T25398 20977-20983 Protein denotes TSST-1
T25397 20919-20925 Protein denotes IL-1RA
T25396 20913-20918 Protein denotes IL-1β
T25395 20879-20885 Protein denotes TSST-1
T25394 20855-20861 Protein denotes TSST-1
T25393 20827-20833 Protein denotes IL-1RA
T25392 20821-20826 Protein denotes IL-1β
T24724 19246-19254 Positive_regulation denotes elevated
T24723 18970-18977 Binding denotes Binding
T24722 18982-18994 Positive_regulation denotes up-regulated
T24721 19648-19654 Protein denotes TSST-1
T24720 19609-19615 Protein denotes TSST-1
T24719 19379-19385 Protein denotes TSST-1
T24718 19300-19306 Protein denotes IL-1RA
T24717 19255-19259 Protein denotes NFAT
T24716 19177-19183 Protein denotes TSST-1
T24715 19160-19166 Protein denotes TSST-1
T24714 19085-19091 Protein denotes TSST-1
T24713 19017-19023 Protein denotes TSST-1
T24712 18953-18959 Protein denotes IL-1RA
T24711 18896-18902 Protein denotes TSST-1
T23824 13111-13121 Gene_expression denotes production
T23823 12861-12871 Gene_expression denotes production
T23822 12467-12476 Negative_regulation denotes reduction
T23821 12486-12496 Gene_expression denotes production
T23820 12303-12313 Gene_expression denotes production
T23819 12199-12213 Negative_regulation denotes down-regulated
T23818 13297-13303 Protein denotes IL-1RA
T23817 13270-13276 Protein denotes TSST-1
T23816 13176-13182 Protein denotes TSST-1
T23815 13104-13110 Protein denotes IL-1RA
T23814 13054-13060 Protein denotes TSST-1
T23798 12243-12249 Protein denotes TSST-1
T23797 12189-12194 Protein denotes IL-1β
T24135 18618-18626 Positive_regulation denotes enhanced
T24134 18710-18716 Protein denotes TSST-1
T24133 18679-18685 Protein denotes TSST-1
T24132 18649-18655 Protein denotes TSST-1
T24131 18589-18595 Protein denotes IL-1RA
T24130 18539-18545 Protein denotes TSST-1
T22834 10479-10487 Gene_expression denotes positive
T22833 10581-10589 Gene_expression denotes positive
T22832 10700-10708 Gene_expression denotes positive
T22831 10604-10607 Protein denotes p65
T22830 10599-10602 Protein denotes p50
T22829 10529-10534 Protein denotes c-rel
T22828 10524-10527 Protein denotes p52
T22827 10740-10742 Protein denotes c1
T22826 10731-10738 Protein denotes NFAT c2
T22825 10723-10726 Protein denotes p50
T22824 10718-10721 Protein denotes p65
T22823 10624-10626 Protein denotes c2
T22822 10616-10622 Protein denotes NFATc1
T22821 10379-10383 Protein denotes NFAT
T22820 10239-10241 Protein denotes c1
T22819 10232-10238 Protein denotes NFATc2
T22818 10224-10227 Protein denotes p50
T22817 10220-10223 Protein denotes p65
T22281 8976-8983 Binding denotes binding
T22280 9947-9953 Protein denotes TSST-1
T22279 9765-9771 Protein denotes TSST-1
T22278 9739-9745 Protein denotes TSST-1
T22277 9676-9682 Protein denotes TSST-1
T22276 9661-9667 Protein denotes TSST-1
T22275 9641-9647 Protein denotes TSST-1
T22274 9506-9509 Protein denotes p50
T22273 9497-9500 Protein denotes p65
T22272 9483-9487 Protein denotes IL-8
T22271 9375-9379 Protein denotes IL-8
T22270 9356-9362 Protein denotes NFIL-6
T22269 9336-9340 Protein denotes NFAT
T22268 9241-9245 Protein denotes IL-8
T22267 9232-9236 Protein denotes IL-6
T22266 9226-9230 Protein denotes TNFα
T22265 9220-9224 Protein denotes IFNγ
T22264 9172-9176 Protein denotes IL-8
T22263 9157-9163 Protein denotes NFIL-6
T22262 9145-9149 Protein denotes NFAT
T22261 9002-9008 Protein denotes NFIL-6
T22260 8987-8991 Protein denotes NFAT
T20956 38830-38837 Binding denotes binding
T20955 38804-38811 Negative_regulation denotes inhibit
T20954 39932-39938 Protein denotes IL-1RA
T20953 39682-39687 Protein denotes GAPDH
T20952 39671-39677 Protein denotes IL-1RA
T20951 39489-39495 Protein denotes IL-1RA
T20950 39420-39421 Protein denotes 3
T20949 39413-39419 Protein denotes NFATP2
T20948 39360-39366 Protein denotes NFIL-6
T20947 38870-38876 Protein denotes IL-1RA
T21364 40720-40726 Protein denotes TSST-1
T21363 40707-40713 Protein denotes TSST-1
T21362 40435-40441 Protein denotes TSST-1
T21361 40422-40428 Protein denotes TSST-1
T20214 38342-38346 Protein denotes IL-1
T20213 38298-38302 Protein denotes IL-2
T20212 38228-38234 Protein denotes TGFβ 1
T20211 38156-38160 Protein denotes IL-8
T20210 38145-38151 Protein denotes IL-1RA
T20209 38070-38074 Protein denotes IL-6
T20208 38061-38065 Protein denotes IL-1
T20207 38055-38059 Protein denotes TNFα
T20206 38049-38053 Protein denotes IFNγ
T19697 37240-37246 Protein denotes NFATc1
T19696 37212-37218 Protein denotes NFATc2
T19695 37186-37191 Protein denotes c-rel
T19694 37127-37130 Protein denotes p52
T19693 37101-37104 Protein denotes p65
T19692 37073-37076 Protein denotes p50
T19691 36967-36972 Protein denotes c-Rel
T19690 36944-36947 Protein denotes p52
T19689 36686-36690 Protein denotes NFAT
T19164 36496-36502 Negative_regulation denotes excess
T19163 36506-36511 Protein denotes Oct-1
T19162 36400-36402 Protein denotes 50
T19161 36396-36399 Protein denotes p65
T18764 35501-35508 Positive_regulation denotes crucial
T18763 35517-35524 Binding denotes binding
T18762 35528-35532 Protein denotes NFAT
T18761 35417-35421 Protein denotes TNFα
T18760 35359-35363 Protein denotes IFNγ
T18759 34889-34893 Protein denotes IL-6
T18758 34880-34884 Protein denotes IFNγ
T18757 34874-34878 Protein denotes IL-8
T18756 34868-34872 Protein denotes TNFα
T18230 34702-34708 Protein denotes TSST-1
T18229 34454-34460 Protein denotes TSST-1
T17434 32595-32602 Binding denotes binding
T17433 32693-32702 Regulation denotes regulated
T17432 32946-32952 Protein denotes IL-1RA
T17431 32940-32945 Protein denotes IL-1β
T17430 32654-32660 Protein denotes IL-1RA
T17429 32457-32463 Protein denotes IL-1RA
T17428 32427-32433 Protein denotes TSST-1
T17427 32377-32383 Protein denotes TSST-1
T16580 28386-28392 Protein denotes IL-1RA
T16579 28380-28385 Protein denotes IL-1β
T16578 28365-28371 Protein denotes TSST-1
T16577 28201-28207 Protein denotes TSST-1
T16576 27682-27688 Protein denotes IL-1RA
T16575 27651-27655 Protein denotes IL-8
T16574 27548-27576 Protein denotes p38 mitogen-activated kinase
T16573 27512-27516 Protein denotes TNFα
T16572 27503-27507 Protein denotes IFNγ
T16571 27388-27394 Protein denotes TSST-1
T16570 27347-27351 Protein denotes TNFα
T16569 27222-27242 Protein denotes Toll-like receptor 4
T16568 27161-27167 Protein denotes TSST-1
T16567 27076-27082 Protein denotes TSST-1
T16566 26946-26952 Protein denotes IL-1RA
T16565 26933-26937 Protein denotes IL-8
T16564 26822-26828 Protein denotes IL-1RA
T16563 26708-26714 Protein denotes IL-1RA
T16562 26543-26549 Protein denotes IL-1RA
T16561 26513-26519 Protein denotes IL-1RA
T16560 26482-26488 Protein denotes NFIL-6
T16559 26473-26477 Protein denotes NFAT
T16558 26421-26427 Protein denotes IL-1RA
T16557 26412-26416 Protein denotes IL-6
T16556 26406-26410 Protein denotes IFNγ
T16555 26388-26392 Protein denotes NFAT
T16554 26254-26260 Protein denotes NFIL-6
T16553 26248-26249 Protein denotes 3
T16552 26241-26247 Protein denotes NFATP2
T16551 25923-25929 Protein denotes IL-1RA
T16550 25842-25848 Protein denotes IL-1RA
T16549 25811-25816 Protein denotes IL-1β
T16548 25771-25777 Protein denotes TSST-1
T16547 25583-25588 Protein denotes IL-1β
T16546 25574-25578 Protein denotes TNFα
T16545 25499-25502 Protein denotes p65
T16544 25451-25455 Protein denotes IL-8
T16543 25409-25413 Protein denotes IL-8
T16542 25381-25387 Protein denotes NFATc2
T16541 25363-25369 Protein denotes NFIL-6
T16540 25355-25358 Protein denotes p65
T16539 25283-25287 Protein denotes IL-8
T16538 25249-25253 Protein denotes IL-8
T16537 25188-25190 Protein denotes 50
T16536 25184-25187 Protein denotes p65
T16535 25154-25156 Protein denotes 65
T16534 25150-25153 Protein denotes p65
T16533 25095-25099 Protein denotes IL-8
T16532 24936-24939 Protein denotes p65
T16531 25000-25004 Protein denotes IL-8
T16530 24966-24969 Protein denotes p50
T16529 24797-24803 Protein denotes IL-1RA
T16528 24778-24782 Protein denotes IL-8
T16527 24668-24674 Protein denotes IL-1RA
T16526 24659-24663 Protein denotes IL-8
T16525 24473-24477 Protein denotes NFAT
T16524 24383-24387 Protein denotes NFAT
T16523 24301-24305 Protein denotes NFAT
T16522 24289-24295 Protein denotes NFIL-6
T16685 32010-32019 Positive_regulation denotes activated
T16684 31684-31694 Positive_regulation denotes activation
T16683 31608-31618 Gene_expression denotes production
T16682 31577-31585 Regulation denotes controls
T16681 31085-31094 Positive_regulation denotes dependent
T16680 31071-31078 Positive_regulation denotes induced
T16679 31052-31059 Negative_regulation denotes reduced
T16678 31100-31110 Gene_expression denotes production
T16677 30783-30789 Negative_regulation denotes excess
T16676 30652-30660 Negative_regulation denotes decrease
T16675 30544-30551 Positive_regulation denotes induced
T16674 30559-30569 Gene_expression denotes production
T16673 30516-30529 Positive_regulation denotes up-regulation
T16672 29377-29390 Positive_regulation denotes up-regulation
T16671 28926-28937 Positive_regulation denotes enhancement
T16670 28967-28977 Gene_expression denotes production
T16669 28952-28959 Positive_regulation denotes induced
T16668 28632-28639 Binding denotes binding
T16667 28624-28631 Positive_regulation denotes induced
T16666 28523-28536 Positive_regulation denotes up-regulation
T16665 28447-28462 Negative_regulation denotes down-regulation
T16664 28372-28379 Positive_regulation denotes induced
T16663 27629-27650 Positive_regulation denotes neutrophil-attracting
T16662 27612-27621 Positive_regulation denotes induction
T16661 27408-27415 Binding denotes binding
T16660 27485-27492 Localization denotes release
T16659 27474-27481 Positive_regulation denotes leading
T16658 27301-27311 Gene_expression denotes expression
T16657 26925-26932 Gene_expression denotes produce
T16620 31080-31084 Protein denotes IL-1
T16656 26814-26821 Gene_expression denotes produce
T16655 26695-26704 Positive_regulation denotes induction
T16654 26455-26463 Negative_regulation denotes decrease
T16653 26681-26690 Positive_regulation denotes necessary
T16652 26489-26496 Binding denotes binding
T16651 26567-26574 Positive_regulation denotes induced
T16650 26355-26364 Positive_regulation denotes activated
T16649 26289-26292 Positive_regulation denotes due
T16648 26265-26272 Binding denotes binding
T16647 26184-26189 Positive_regulation denotes leads
T16646 26228-26237 Positive_regulation denotes induction
T16645 25834-25841 Positive_regulation denotes induced
T16644 25804-25810 Positive_regulation denotes induce
T16643 25288-25301 Transcription denotes transcription
T16642 25271-25282 Positive_regulation denotes GP-mediated
T16641 25394-25401 Binding denotes binding
T16640 25335-25349 Positive_regulation denotes transactivated
T16639 25237-25248 Positive_regulation denotes GP-mediated
T16638 25082-25091 Positive_regulation denotes induction
T16637 25100-25113 Transcription denotes transcription
T16636 25254-25267 Transcription denotes transcription
T16635 25127-25137 Positive_regulation denotes activation
T16634 24920-24927 Binding denotes binding
T16633 24804-24814 Gene_expression denotes production
T16632 24388-24395 Binding denotes binding
T16631 24441-24451 Positive_regulation denotes activation
T16630 24263-24270 Positive_regulation denotes induced
T16629 24271-24278 Binding denotes binding
T16628 32024-32030 Protein denotes IL-1RA
T16627 31698-31702 Protein denotes NFAT
T16626 31602-31607 Protein denotes IL-1β
T16625 31587-31593 Protein denotes IL-1RA
T16624 31362-31368 Protein denotes TSST-1
T16623 31346-31352 Protein denotes TSST-1
T16622 31064-31070 Protein denotes TSST-1
T16621 31095-31099 Protein denotes IL-2
T16619 30993-30998 Protein denotes IL-1β
T16618 30919-30925 Protein denotes TSST-1
T16617 30891-30897 Protein denotes IL-1RA
T16616 30885-30890 Protein denotes IL-1β
T16615 30851-30855 Protein denotes IL-1
T16614 30805-30810 Protein denotes IL-1β
T16613 30793-30799 Protein denotes IL-1RA
T16612 30702-30708 Protein denotes TSST-1
T16611 30674-30680 Protein denotes IL-1RA
T16610 30668-30673 Protein denotes IL-1β
T16609 30552-30558 Protein denotes IL-1RA
T16608 30537-30543 Protein denotes TSST-1
T16607 30364-30370 Protein denotes TSST-1
T16606 30158-30164 Protein denotes TSST-1
T16605 29948-29954 Protein denotes IL-1RA
T16604 29647-29653 Protein denotes IL-1RA
T16603 29634-29638 Protein denotes TNFα
T16602 29432-29438 Protein denotes IL-1RA
T16601 29349-29353 Protein denotes TNFα
T16600 29305-29311 Protein denotes TSST-1
T16599 29149-29155 Protein denotes TSST-1
T16598 29096-29102 Protein denotes TSST-1
T16597 29068-29074 Protein denotes IL-1RA
T16596 28960-28966 Protein denotes IL-1RA
T16595 28945-28951 Protein denotes TSST-1
T16594 28869-28873 Protein denotes TNFα
T16593 28820-28826 Protein denotes TSST-1
T16592 28774-28778 Protein denotes IFNγ
T16591 28766-28770 Protein denotes IL-6
T16590 28759-28764 Protein denotes IL-1β
T16589 28753-28757 Protein denotes TNFα
T16588 28722-28728 Protein denotes IL-1RA
T16587 28713-28717 Protein denotes IL-8
T16586 28660-28664 Protein denotes NFAT
T16585 28649-28655 Protein denotes NFIL-6
T16584 28617-28623 Protein denotes TSST-1
T16583 28540-28546 Protein denotes IL-1RA
T16582 28476-28480 Protein denotes IL-6
T16581 28466-28471 Protein denotes IL-1β
T11196 22797-22804 Localization denotes release
T11195 22780-22789 Negative_regulation denotes decreased
T11194 22448-22456 Negative_regulation denotes decrease
T11193 21994-22003 Negative_regulation denotes reduction
T11192 21724-21732 Positive_regulation denotes relevant
T11191 21741-21750 Positive_regulation denotes induction
T11190 21583-21590 Negative_regulation denotes reduced
T11189 22790-22796 Protein denotes IL-1RA
T11188 22572-22578 Protein denotes IL-1RA
T11187 22460-22466 Protein denotes IL-1RA
T11186 22319-22325 Protein denotes IL-1RA
T11185 22023-22029 Protein denotes IL-1RA
T11184 22007-22013 Protein denotes IL-1RA
T11183 21974-21980 Protein denotes IL-1RA
T11182 21843-21849 Protein denotes NFIL-6
T11181 21826-21830 Protein denotes NFAT
T11180 21754-21760 Protein denotes IL-1RA
T11179 21704-21710 Protein denotes IL-1RA
T11178 21591-21597 Protein denotes IL-1RA
T10290 20621-20629 Negative_regulation denotes decrease
T10289 20652-20659 Localization denotes release
T10288 20497-20507 Gene_expression denotes production
T10287 20005-20015 Positive_regulation denotes generating
T10286 19993-20001 Positive_regulation denotes resulted
T10285 19682-19689 Positive_regulation denotes induced
T10284 19661-19670 Regulation denotes modulated
T10283 20743-20749 Protein denotes TSST-1
T10282 20730-20736 Protein denotes TSST-1
T10281 20706-20712 Protein denotes TSST-1
T10280 20663-20667 Protein denotes IL-2
T10279 20637-20641 Protein denotes IL-1
T10278 20526-20531 Protein denotes IL-1β
T10277 20511-20517 Protein denotes IL-1RA
T10276 20332-20338 Protein denotes TSST-1
T10275 20310-20316 Protein denotes TSST-1
T10274 20272-20278 Protein denotes TSST-1
T10273 20186-20192 Protein denotes IL-1RA
T10272 20180-20185 Protein denotes IL-1β
T10271 20032-20038 Protein denotes IL-1RA
T10270 20021-20026 Protein denotes IL-1β
T10269 19899-19905 Protein denotes IL-1RA
T10268 19893-19898 Protein denotes IL-1β
T10267 19784-19790 Protein denotes IL-1RA
T10266 19774-19779 Protein denotes IL-1β
T10265 19696-19702 Protein denotes IL-1RA
T10264 19690-19695 Protein denotes IL-1β
T10263 19675-19681 Protein denotes TSST-1
T7649 10966-10970 Protein denotes IL-8
T7648 10960-10964 Protein denotes TNFα
T7647 11095-11099 Protein denotes IFNγ
T9362 18222-18229 Binding denotes binding
T9361 18348-18356 Positive_regulation denotes elevated
T9360 17547-17561 Negative_regulation denotes down-regulated
T9359 17405-17413 Positive_regulation denotes elevated
T9358 16340-16347 Positive_regulation denotes induced
T9356 16304-16314 Gene_expression denotes expression
T9357 16482-16486 Binding denotes bind
T9355 16289-16296 Positive_regulation denotes induced
T9354 16232-16239 Binding denotes binding
T9353 16202-16206 Regulation denotes Role
T9352 18336-18342 Protein denotes TSST-1
T9351 18301-18307 Protein denotes TSST-1
T9350 17906-17912 Protein denotes TSST-1
T9349 17832-17838 Protein denotes TSST-1
T9348 17468-17474 Protein denotes TSST-1
T9347 17423-17429 Protein denotes TSST-1
T9346 17291-17297 Protein denotes TSST-1
T9345 17230-17236 Protein denotes TSST-1
T9344 17096-17102 Protein denotes TSST-1
T9343 17000-17006 Protein denotes TSST-1
T9342 16620-16626 Protein denotes IL-1RA
T9341 16503-16509 Protein denotes IL-1RA
T9340 16413-16417 Protein denotes IFNγ
T9339 16405-16409 Protein denotes IL-6
T9338 16399-16403 Protein denotes TNFα
T9337 16297-16303 Protein denotes IL-1RA
T9336 16282-16288 Protein denotes TSST-1
T9335 16249-16255 Protein denotes TSST-1
T9334 16227-16231 Protein denotes NFAT
T9333 16216-16222 Protein denotes NFIL-6
T7646 10891-10897 Protein denotes TSST-1
T7645 10861-10867 Protein denotes TSST-1
T7759 16016-16023 Positive_regulation denotes induced
T7758 15958-15968 Gene_expression denotes production
T7757 15708-15718 Gene_expression denotes production
T7756 15798-15813 Negative_regulation denotes down-regulation
T7755 15691-15699 Positive_regulation denotes increase
T7754 15603-15613 Gene_expression denotes production
T7753 15454-15463 Localization denotes secretion
T7752 15439-15445 Negative_regulation denotes effect
T7751 15280-15286 Regulation denotes change
T7750 15296-15306 Gene_expression denotes production
T7749 15147-15157 Gene_expression denotes production
T7748 15009-15016 Positive_regulation denotes induced
T7747 14821-14832 Gene_expression denotes productions
T7746 14687-14695 Positive_regulation denotes elevated
T7745 14707-14714 Positive_regulation denotes induced
T7744 14473-14481 Positive_regulation denotes increase
T7743 14492-14502 Gene_expression denotes production
T7742 14407-14417 Gene_expression denotes production
T7741 14368-14373 Regulation denotes alter
T7740 14203-14211 Gene_expression denotes produced
T7739 14033-14043 Gene_expression denotes production
T7738 13894-13902 Positive_regulation denotes resulted
T7737 13941-13951 Gene_expression denotes production
T7736 13924-13932 Positive_regulation denotes increase
T7735 13753-13760 Positive_regulation denotes induced
T7734 13780-13790 Gene_expression denotes production
T7733 13554-13563 Negative_regulation denotes decreased
T7732 13569-13579 Gene_expression denotes production
T7731 13505-13515 Gene_expression denotes production
T7730 13405-13412 Positive_regulation denotes induced
T7729 13470-13480 Regulation denotes alteration
T7728 13488-13499 Positive_regulation denotes LPS-induced
T7727 12104-12113 Negative_regulation denotes reduction
T7726 12128-12135 Positive_regulation denotes induced
T7725 11919-11928 Negative_regulation denotes reduction
T7724 11796-11809 Positive_regulation denotes up-regulation
T7723 11819-11829 Gene_expression denotes production
T7722 11710-11720 Gene_expression denotes production
T7721 11063-11073 Gene_expression denotes production
T7720 11055-11059 Positive_regulation denotes lead
T7719 16160-16166 Protein denotes TSST-1
T7718 16147-16153 Protein denotes TSST-1
T7717 16103-16109 Protein denotes TSST-1
T7716 16001-16007 Protein denotes TGFβ 1
T7715 15991-15996 Protein denotes IL-10
T7714 15985-15989 Protein denotes IL-4
T7713 15978-15983 Protein denotes IL-12
T7712 15972-15976 Protein denotes IL-2
T7711 15948-15953 Protein denotes TGFβ1
T7710 15941-15946 Protein denotes IL-10
T7709 15935-15939 Protein denotes IL-4
T7708 15928-15933 Protein denotes IL-12
T7707 15922-15926 Protein denotes IL-2
T7706 15884-15890 Protein denotes TSST-1
T7705 15871-15877 Protein denotes TSST-1
T7704 15829-15835 Protein denotes TSST-1
T7703 15703-15707 Protein denotes IFNγ
T7702 15598-15602 Protein denotes IFNγ
T7701 15590-15594 Protein denotes IFNγ
T7700 15449-15453 Protein denotes TNFα
T7699 15392-15398 Protein denotes TSST-1
T7698 15379-15385 Protein denotes TSST-1
T7697 15291-15295 Protein denotes TNFα
T7696 15142-15146 Protein denotes TNFα
T7695 15121-15125 Protein denotes TNFα
T7694 15044-15050 Protein denotes IL-1RA
T7693 15035-15039 Protein denotes IL-8
T7692 14924-14930 Protein denotes IL-1RA
T7691 14915-14919 Protein denotes IL-8
T7690 14814-14820 Protein denotes IL-1RA
T7689 14805-14809 Protein denotes IL-8
T7688 14725-14731 Protein denotes IL-1RA
T7687 14700-14706 Protein denotes TSST-1
T7686 14620-14626 Protein denotes TSST-1
T7685 14539-14545 Protein denotes TSST-1
T7684 14485-14491 Protein denotes IL-1RA
T7683 14443-14449 Protein denotes TSST-1
T7682 14400-14406 Protein denotes IL-1RA
T7681 14164-14170 Protein denotes IL-1RA
T7680 14158-14162 Protein denotes IL-8
T7679 14143-14149 Protein denotes IL-1RA
T7678 14096-14102 Protein denotes TSST-1
T7677 14083-14089 Protein denotes TSST-1
T7676 14059-14065 Protein denotes TSST-1
T7675 14028-14032 Protein denotes IL-8
T7674 13936-13940 Protein denotes IL-8
T7673 13775-13779 Protein denotes IL-8
T7672 13731-13735 Protein denotes IL-8
T7671 13626-13632 Protein denotes TSST-1
T7670 13613-13619 Protein denotes TSST-1
T7669 13589-13595 Protein denotes TSST-1
T7668 13564-13568 Protein denotes IL-6
T7667 13500-13504 Protein denotes IL-6
T7666 13436-13440 Protein denotes IL-6
T7665 13397-13401 Protein denotes IL-6
T7664 12146-12151 Protein denotes IL-1β
T7663 12121-12127 Protein denotes TSST-1
T7662 12039-12045 Protein denotes TSST-1
T7661 12001-12007 Protein denotes TSST-1
T7660 11932-11937 Protein denotes IL-1β
T7659 11889-11895 Protein denotes TSST-1
T7658 11813-11818 Protein denotes IL-1β
T7657 11704-11709 Protein denotes IL-1β
T7656 11685-11690 Protein denotes IL-1β
T7655 11671-11677 Protein denotes TSST-1
T7654 11089-11093 Protein denotes IL-6
T7653 11083-11087 Protein denotes IL-8
T7652 11077-11081 Protein denotes TNFα
T7651 10981-10985 Protein denotes IFNγ
T7650 10972-10976 Protein denotes IL-6
T849 1679-1683 Protein denotes IL-6
T850 1732-1738 Protein denotes TSST-1
T851 1747-1752 Protein denotes IL-1β
T852 1753-1759 Protein denotes IL-1RA
T853 1851-1857 Protein denotes TSST-1
T854 1867-1871 Protein denotes IL-1
T855 1896-1900 Protein denotes IL-2
T856 2102-2108 Protein denotes IL-1RA
T857 2199-2205 Protein denotes IL-1RA
T858 17-26 Regulation denotes modulates
T859 31-38 Binding denotes binding
T860 750-760 Gene_expression denotes production
T861 631-641 Positive_regulation denotes activation
T862 817-824 Positive_regulation denotes induced
T863 961-968 Binding denotes binding
T864 882-889 Positive_regulation denotes induced
T865 1062-1072 Gene_expression denotes production
T866 1022-1030 Positive_regulation denotes increase
T867 1212-1219 Binding denotes binding
T868 1192-1199 Positive_regulation denotes induced
T869 1451-1459 Positive_regulation denotes elevated
T870 1496-1503 Binding denotes binding
T871 1484-1491 Positive_regulation denotes induced
T872 1530-1537 Positive_regulation denotes leading
T873 1555-1563 Positive_regulation denotes increase
T874 1656-1665 Negative_regulation denotes reduction
T875 1622-1629 Positive_regulation denotes induced
T876 1739-1746 Positive_regulation denotes induced
T877 1882-1892 Gene_expression denotes production
T878 1858-1865 Positive_regulation denotes induced
T879 1837-1846 Negative_regulation denotes decreased
T880 2225-2234 Regulation denotes modulated
T881 2181-2191 Regulation denotes regulation
T2934 2732-2740 Protein denotes Dectin-1
T2935 3007-3015 Protein denotes Dectin-1
T2936 3042-3046 Protein denotes TNFα
T2937 3055-3075 Protein denotes Toll-like receptor 2
T2938 3100-3105 Protein denotes MyD88
T2939 3202-3208 Protein denotes NFIL-6
T2940 3461-3465 Protein denotes IL-1
T2941 3467-3471 Protein denotes IL-6
T2942 3473-3477 Protein denotes TNFα
T2943 3549-3555 Protein denotes IL-1RA
T2944 3565-3569 Protein denotes IL-1
T2945 3771-3775 Protein denotes IL-8
T2946 4917-4923 Protein denotes TSST-1
T2947 5048-5052 Protein denotes TNFα
T2948 5054-5059 Protein denotes IL-1β
T2949 5061-5065 Protein denotes IL-6
T2950 5067-5071 Protein denotes IL-8
T2951 5076-5082 Protein denotes IL-1RA
T2952 5108-5112 Protein denotes IFNγ
T2953 5114-5118 Protein denotes IL-2
T2954 5120-5124 Protein denotes IL-4
T2955 5126-5131 Protein denotes IL-10
T2956 5133-5138 Protein denotes IL-12
T2957 5143-5148 Protein denotes TGFβ1
T2958 5192-5196 Protein denotes TNFα
T2959 5266-5270 Protein denotes IL-8
T2960 5308-5312 Protein denotes IFNγ
T2961 5371-5375 Protein denotes IL-6
T2962 5446-5452 Protein denotes IL-1RA
T2963 5508-5514 Protein denotes IL-1RA
T2964 5627-5633 Protein denotes IL-1RA
T2965 5822-5828 Protein denotes IL-1RA
T2966 3016-3024 Positive_regulation denotes resulted
T2967 3028-3038 Gene_expression denotes production
T2968 2985-2992 Binding denotes binding
T2969 3184-3192 Positive_regulation denotes activate
T2970 3420-3429 Localization denotes secretion
T2971 3513-3523 Gene_expression denotes production
T2972 3631-3638 Positive_regulation denotes induced
T2973 3763-3770 Gene_expression denotes produce
T2974 5468-5475 Binding denotes binding
T4267 5877-5883 Protein denotes NFIL-6
T4268 5888-5892 Protein denotes NFAT
T4269 5916-5920 Protein denotes TNFα
T4270 5922-5926 Protein denotes IL-6
T4271 5931-5935 Protein denotes IFNγ
T4272 5996-6002 Protein denotes TSST-1
T4273 6026-6032 Protein denotes TSST-1
T4274 6223-6227 Protein denotes IL-8
T4275 6263-6267 Protein denotes IL-6
T4276 6098-6104 Protein denotes NFIL-6
T4277 6187-6191 Protein denotes TNFα
T4278 6397-6403 Protein denotes TSST-1
T4279 6475-6479 Protein denotes IL-8
T4280 6544-6547 Protein denotes p65
T4281 6574-6577 Protein denotes p50
T4282 6689-6692 Protein denotes p65
T4283 6718-6721 Protein denotes p50
T4284 6731-6734 Protein denotes p52
T4285 6863-6867 Protein denotes TNFα
T4286 6934-6940 Protein denotes TSST-1
T4287 6979-6985 Protein denotes TSST-1
T4288 7063-7069 Protein denotes TSST-1
T4289 7100-7106 Protein denotes TSST-1
T4290 7130-7136 Protein denotes TSST-1
T4291 7235-7239 Protein denotes NFAT
T4292 7261-7265 Protein denotes IFNγ
T4293 7308-7312 Protein denotes NFAT
T4294 7359-7365 Protein denotes NFATc2
T4295 7392-7398 Protein denotes NFATc1
T4296 5849-5856 Binding denotes Binding
T4297 5946-5955 Positive_regulation denotes following
T4298 6068-6075 Binding denotes binding
T4299 6528-6535 Binding denotes binding
T4300 6739-6747 Gene_expression denotes negative
T4301 6673-6680 Binding denotes binding
T4302 7201-7208 Binding denotes binding
T4303 7348-7355 Binding denotes binding
T26287 27870-27876 Protein denotes IL-1RA
T824 69-73 Protein denotes IL-6
T825 119-124 Protein denotes IL-1β
T826 125-149 Protein denotes IL-1 receptor antagonist
T827 572-600 Protein denotes toxic shock syndrome toxin 1
T828 602-608 Protein denotes TSST-1
T829 771-775 Protein denotes IL-6
T830 777-800 Protein denotes tumor necrosis factor α
T831 804-816 Protein denotes interferon γ
T832 668-687 Protein denotes NFinterleukin(IL)-6
T833 692-696 Protein denotes NFAT
T834 715-721 Protein denotes TSST-1
T835 764-769 Protein denotes IL-1β
T836 914-918 Protein denotes IL-8
T837 1004-1008 Protein denotes IL-8
T838 1034-1057 Protein denotes IL-1receptor antagonist
T839 1058-1060 Protein denotes RA
T840 1162-1166 Protein denotes IL-8
T841 1274-1280 Protein denotes IL-1RA
T842 1385-1391 Protein denotes TSST-1
T843 1477-1483 Protein denotes TSST-1
T844 1513-1519 Protein denotes NFIL-6
T845 1524-1528 Protein denotes NFAT
T846 1567-1573 Protein denotes IL-1RA
T847 1615-1621 Protein denotes TSST-1
T848 1669-1674 Protein denotes IL-1β
T23813 12956-12962 Protein denotes TSST-1
T23812 12943-12949 Protein denotes TSST-1
T23811 12854-12860 Protein denotes IL-1RA
T23810 12824-12830 Protein denotes TSST-1
T23809 12786-12792 Protein denotes TSST-1
T23808 12748-12754 Protein denotes IL-1RA
T23807 12652-12657 Protein denotes IL-1β
T23806 12623-12629 Protein denotes TSST-1
T23805 12536-12542 Protein denotes TSST-1
T23804 12512-12518 Protein denotes TSST-1
T23803 12480-12485 Protein denotes IL-1β
T23802 12398-12404 Protein denotes TSST-1
T23801 12385-12391 Protein denotes TSST-1
T23800 12297-12302 Protein denotes IL-1β
T23799 12267-12273 Protein denotes TSST-1
R219 T870 T869 themeOf binding,elevated
R220 T870 T871 themeOf binding,induced
R221 T870 T871 themeOf binding,induced
R222 T873 T872 themeOf increase,leading
R349 T843 T871 causeOf TSST-1,induced
R350 T843 T871 causeOf TSST-1,induced
R351 T844 T870 themeOf NFIL-6,binding
R352 T845 T870 themeOf NFAT,binding
R353 T846 T873 themeOf IL-1RA,increase
R7411 T11178 T11190 themeOf IL-1RA,reduced
R7412 T11180 T11191 themeOf IL-1RA,induction
R7413 T11184 T11193 themeOf IL-1RA,reduction
R7414 T11185 T11193 themeOf IL-1RA,reduction
R7415 T11187 T11194 themeOf IL-1RA,decrease
R7416 T11189 T11196 themeOf IL-1RA,release
R7417 T11191 T11192 themeOf induction,relevant
R7418 T11196 T11195 themeOf release,decreased
R11338 T16524 T16632 themeOf NFAT,binding
R11339 T16525 T16631 themeOf NFAT,activation
R11341 T16528 T16633 themeOf IL-8,production
R11342 T16529 T16633 themeOf IL-1RA,production
R11343 T16532 T16634 themeOf p65,binding
R11344 T16533 T16637 themeOf IL-8,transcription
R11345 T16534 T16635 themeOf p65,activation
R11347 T16536 T16635 themeOf p65,activation
R11348 T16538 T16636 themeOf IL-8,transcription
R11350 T16539 T16643 themeOf IL-8,transcription
R11351 T16540 T16640 themeOf p65,transactivated
R11352 T16541 T16640 themeOf NFIL-6,transactivated
R11353 T16541 T16641 themeOf NFIL-6,binding
R11354 T16542 T16641 themeOf NFATc2,binding
R11357 T16581 T16665 themeOf IL-1β,down-regulation
R11358 T16548 T16644 causeOf TSST-1,induce
R11359 T16548 T16645 causeOf TSST-1,induced
R11360 T16549 T16644 themeOf IL-1β,induce
R11361 T16550 T16645 themeOf IL-1RA,induced
R11362 T16552 T16646 themeOf NFATP2,induction
R11363 T16552 T16648 themeOf NFATP2,binding
R11364 T16553 T16646 themeOf 3,induction
R11365 T16553 T16648 themeOf 3,binding
R11366 T16554 T16646 themeOf NFIL-6,induction
R11367 T16554 T16648 themeOf NFIL-6,binding
R11368 T16554 T16648 themeOf NFIL-6,binding
R11369 T16555 T16650 themeOf NFAT,activated
R11370 T16559 T16652 themeOf NFAT,binding
R11371 T16559 T16652 themeOf NFAT,binding
R11372 T16559 T16651 themeOf NFAT,induced
R11373 T16559 T16654 themeOf NFAT,decrease
R11374 T16560 T16652 themeOf NFIL-6,binding
R11375 T16560 T16652 themeOf NFIL-6,binding
R11376 T16560 T16654 themeOf NFIL-6,decrease
R11377 T16561 T16652 themeOf IL-1RA,binding
R11378 T16561 T16652 themeOf IL-1RA,binding
R11379 T16562 T16652 themeOf IL-1RA,binding
R11380 T16562 T16652 themeOf IL-1RA,binding
R11381 T16563 T16655 themeOf IL-1RA,induction
R11382 T16564 T16656 themeOf IL-1RA,produce
R11383 T16565 T16657 themeOf IL-8,produce
R11384 T16570 T16658 themeOf TNFα,expression
R11385 T16571 T16661 themeOf TSST-1,binding
R11386 T16582 T16665 themeOf IL-6,down-regulation
R11387 T16572 T16660 themeOf IFNγ,release
R11388 T16573 T16660 themeOf TNFα,release
R11389 T16575 T16662 themeOf IL-8,induction
R11390 T16575 T16663 themeOf IL-8,neutrophil-attracting
R11391 T16583 T16666 themeOf IL-1RA,up-regulation
R11392 T16576 T16662 themeOf IL-1RA,induction
R11393 T16576 T16663 themeOf IL-1RA,neutrophil-attracting
R11394 T16578 T16664 causeOf TSST-1,induced
R11395 T16584 T16667 themeOf TSST-1,induced
R11396 T16579 T16664 themeOf IL-1β,induced
R11397 T16585 T16668 themeOf NFIL-6,binding
R11398 T16586 T16668 themeOf NFAT,binding
R11399 T16587 T16668 themeOf IL-8,binding
R11400 T16678 T16681 themeOf production,dependent
R11401 T16678 T16679 themeOf production,reduced
R11402 T16678 T16680 themeOf production,induced
R11403 T16587 T16668 themeOf IL-8,binding
R11404 T16595 T16669 causeOf TSST-1,induced
R11405 T16683 T16682 themeOf production,controls
R11406 T16596 T16670 themeOf IL-1RA,production
R11407 T16602 T16672 themeOf IL-1RA,up-regulation
R11409 T16608 T16675 causeOf TSST-1,induced
R11412 T16609 T16674 themeOf IL-1RA,production
R11413 T16610 T16676 themeOf IL-1β,decrease
R11418 T16613 T16677 themeOf IL-1RA,excess
R11419 T16614 T16677 themeOf IL-1β,excess
R11420 T16621 T16678 themeOf IL-2,production
R11423 T16622 T16680 causeOf TSST-1,induced
R11424 T16626 T16683 themeOf IL-1β,production
R11425 T16627 T16684 themeOf NFAT,activation
R11428 T16628 T16685 themeOf IL-1RA,activated
R11429 T16629 T16630 themeOf binding,induced
R11430 T16629 T16630 themeOf binding,induced
R11432 T16636 T16639 themeOf transcription,GP-mediated
R11435 T16637 T16638 themeOf transcription,induction
R11436 T16643 T16642 themeOf transcription,GP-mediated
R11440 T16646 T16647 themeOf induction,leads
R11441 T16646 T16647 themeOf induction,leads
R11442 T16646 T16647 themeOf induction,leads
R11444 T16646 T16647 themeOf induction,leads
R11445 T16646 T16647 themeOf induction,leads
R11446 T16646 T16649 themeOf induction,due
R11447 T16646 T16649 themeOf induction,due
R11448 T16646 T16649 themeOf induction,due
R11450 T16646 T16649 themeOf induction,due
R11451 T16646 T16649 themeOf induction,due
R11453 T16648 T16646 themeOf binding,induction
R11456 T16648 T16646 themeOf binding,induction
R11457 T16655 T16653 themeOf induction,necessary
R11459 T16660 T16659 themeOf release,leading
R11462 T16660 T16659 themeOf release,leading
R11463 T16670 T16671 themeOf production,enhancement
R11470 T16670 T16669 themeOf production,induced
R11472 T16674 T16673 themeOf production,up-regulation
R11477 T16674 T16675 themeOf production,induced
R11762 T17430 T17434 themeOf IL-1RA,binding
R11763 T17430 T17433 themeOf IL-1RA,regulated
R12861 T18762 T18763 themeOf NFAT,binding
R12862 T18763 T18764 themeOf binding,crucial
R13183 T19163 T19164 themeOf Oct-1,excess
R14428 T20947 T20956 themeOf IL-1RA,binding
R14429 T20956 T20955 themeOf binding,inhibit
R15305 T22260 T22281 themeOf NFAT,binding
R15306 T22261 T22281 themeOf NFIL-6,binding
R15597 T22822 T22834 themeOf NFATc1,positive
R15598 T22822 T22833 themeOf NFATc1,positive
R15599 T22824 T22832 themeOf p65,positive
R15600 T22825 T22832 themeOf p50,positive
R15601 T22826 T22832 themeOf NFAT c2,positive
R15602 T22830 T22833 themeOf p50,positive
R15603 T22831 T22833 themeOf p65,positive
R16234 T23797 T23819 themeOf IL-1β,down-regulated
R16235 T23800 T23820 themeOf IL-1β,production
R16236 T23803 T23821 themeOf IL-1β,production
R16237 T23804 T23821 themeOf TSST-1,production
R16238 T23811 T23823 themeOf IL-1RA,production
R16239 T23815 T23824 themeOf IL-1RA,production
R16240 T23821 T23822 themeOf production,reduction
R16241 T23821 T23822 themeOf production,reduction
R16445 T24133 T24135 themeOf TSST-1,enhanced
R16854 T24714 T24723 themeOf TSST-1,Binding
R16855 T24714 T24722 themeOf TSST-1,up-regulated
R16856 T24717 T24724 themeOf NFAT,elevated
R17228 T25392 T25410 themeOf IL-1β,Decreased
R17229 T25401 T25411 themeOf IL-1β,generating
R17230 T25401 T25412 themeOf IL-1β,resulted
R17231 T25407 T25413 themeOf TSST-1,production
R17232 T25408 T25413 themeOf IL-1RA,production
R17233 T25409 T25413 themeOf IL-1β,production
R17234 T25413 T25414 themeOf production,reduced
R17235 T25413 T25414 themeOf production,reduced
R17236 T25413 T25414 themeOf production,reduced
R17809 T26136 T26146 themeOf NFAT,binding
R17811 T26137 T26146 themeOf NFIL-6,binding
R17813 T26138 T26146 themeOf IL-1RA,binding
R1819 T2935 T2968 themeOf Dectin-1,binding
R1820 T2936 T2967 themeOf TNFα,production
R1821 T2937 T2967 themeOf Toll-like receptor 2,production
R1822 T2939 T2969 themeOf NFIL-6,activate
R1823 T2940 T2970 themeOf IL-1,secretion
R1824 T2941 T2970 themeOf IL-6,secretion
R1825 T2942 T2970 themeOf TNFα,secretion
R1826 T2943 T2971 themeOf IL-1RA,production
R1827 T2944 T2971 themeOf IL-1,production
R1828 T2945 T2973 themeOf IL-8,produce
R1833 T2963 T2974 themeOf IL-1RA,binding
R1835 T2967 T2966 themeOf production,resulted
R1836 T2967 T2966 themeOf production,resulted
R1837 T2971 T2972 themeOf production,induced
R1838 T2971 T2972 themeOf production,induced
R2699 T4267 T4297 themeOf NFIL-6,following
R2700 T4267 T4296 themeOf NFIL-6,Binding
R2701 T4268 T4296 themeOf NFAT,Binding
R2702 T4270 T4296 themeOf IL-6,Binding
R2703 T4271 T4296 themeOf IFNγ,Binding
R2704 T4276 T4298 themeOf NFIL-6,binding
R2705 T4280 T4299 themeOf p65,binding
R2706 T4281 T4299 themeOf p50,binding
R2707 T4282 T4301 themeOf p65,binding
R2708 T4284 T4300 themeOf p52,negative
R2709 T4291 T4302 themeOf NFAT,binding
R2710 T4294 T4303 themeOf NFATc2,binding
R2711 T4295 T4303 themeOf NFATc1,binding
R4985 T7647 T7721 themeOf IFNγ,production
R4987 T7652 T7721 themeOf TNFα,production
R4988 T7653 T7721 themeOf IL-8,production
R4989 T7654 T7721 themeOf IL-6,production
R4992 T7693 T7748 themeOf IL-8,induced
R4993 T7694 T7748 themeOf IL-1RA,induced
R4994 T7696 T7749 themeOf TNFα,production
R4995 T7697 T7750 themeOf TNFα,production
R4997 T7700 T7753 themeOf TNFα,secretion
R4999 T7702 T7754 themeOf IFNγ,production
R5000 T7703 T7757 themeOf IFNγ,production
R5004 T7666 T7730 themeOf IL-6,induced
R5005 T7667 T7731 themeOf IL-6,production
R5009 T7668 T7732 themeOf IL-6,production
R5012 T7669 T7732 themeOf TSST-1,production
R5013 T7673 T7734 themeOf IL-8,production
R5014 T7721 T7720 themeOf production,lead
R5015 T7721 T7720 themeOf production,lead
R5016 T7721 T7720 themeOf production,lead
R5017 T7721 T7720 themeOf production,lead
R5019 T7674 T7737 themeOf IL-8,production
R5020 T7675 T7739 themeOf IL-8,production
R5021 T7676 T7739 themeOf TSST-1,production
R5022 T7731 T7729 themeOf production,alteration
R5023 T7731 T7728 themeOf production,LPS-induced
R5024 T7732 T7733 themeOf production,decreased
R5025 T7732 T7733 themeOf production,decreased
R5026 T7680 T7740 themeOf IL-8,produced
R5027 T7734 T7735 themeOf production,induced
R5028 T7736 T7738 themeOf increase,resulted
R5029 T7737 T7736 themeOf production,increase
R5030 T7681 T7740 themeOf IL-1RA,produced
R5031 T7682 T7742 themeOf IL-1RA,production
R5032 T7742 T7741 themeOf production,alter
R5033 T7743 T7744 themeOf production,increase
R5034 T7683 T7744 causeOf TSST-1,increase
R5035 T7745 T7746 themeOf induced,elevated
R5036 T7684 T7743 themeOf IL-1RA,production
R5037 T7687 T7745 causeOf TSST-1,induced
R5038 T7750 T7751 themeOf production,change
R5039 T7753 T7752 themeOf secretion,effect
R5040 T7688 T7746 themeOf IL-1RA,elevated
R5041 T7688 T7745 themeOf IL-1RA,induced
R5048 T7689 T7747 themeOf IL-8,productions
R6800 T10289 T10290 themeOf release,decrease
R204 T849 T874 themeOf IL-6,reduction
R205 T850 T876 causeOf TSST-1,induced
R206 T851 T876 themeOf IL-1β,induced
R207 T853 T878 causeOf TSST-1,induced
R208 T855 T877 themeOf IL-2,production
R209 T857 T881 themeOf IL-1RA,regulation
R210 T859 T858 themeOf binding,modulates
R211 T860 T862 themeOf production,induced
R212 T860 T862 themeOf production,induced
R213 T860 T862 themeOf production,induced
R214 T860 T862 themeOf production,induced
R215 T865 T866 themeOf production,increase
R216 T865 T866 themeOf production,increase
R217 T867 T868 themeOf binding,induced
R218 T870 T869 themeOf binding,elevated
R223 T877 T878 themeOf production,induced
R224 T877 T879 themeOf production,decreased
R225 T881 T880 themeOf regulation,modulated
R337 T824 T859 themeOf IL-6,binding
R338 T829 T860 themeOf IL-6,production
R339 T830 T860 themeOf tumor necrosis factor α,production
R340 T831 T860 themeOf interferon γ,production
R341 T832 T861 themeOf NFinterleukin(IL)-6,activation
R342 T833 T861 themeOf NFAT,activation
R343 T835 T860 themeOf IL-1β,production
R344 T836 T864 themeOf IL-8,induced
R345 T837 T863 themeOf IL-8,binding
R346 T838 T865 themeOf IL-1receptor antagonist,production
R347 T839 T865 themeOf RA,production
R348 T841 T867 themeOf IL-1RA,binding
R354 T847 T875 themeOf TSST-1,induced
R355 T848 T874 themeOf IL-1β,reduction
R4990 T7657 T7722 themeOf IL-1β,production
R4991 T7658 T7723 themeOf IL-1β,production
R4996 T7660 T7725 themeOf IL-1β,reduction
R4998 T7663 T7726 causeOf TSST-1,induced
R5001 T7704 T7756 themeOf TSST-1,down-regulation
R5002 T7664 T7726 themeOf IL-1β,induced
R5003 T7664 T7727 themeOf IL-1β,reduction
R5006 T7712 T7758 themeOf IL-2,production
R5007 T7713 T7758 themeOf IL-12,production
R5008 T7714 T7758 themeOf IL-4,production
R5010 T7715 T7758 themeOf IL-10,production
R5011 T7716 T7758 themeOf TGFβ 1,production
R5018 T7723 T7724 themeOf production,up-regulation
R5042 T7757 T7755 themeOf production,increase
R5043 T7758 T7759 themeOf production,induced
R5044 T7758 T7759 themeOf production,induced
R5045 T7758 T7759 themeOf production,induced
R5046 T7758 T7759 themeOf production,induced
R5047 T7758 T7759 themeOf production,induced
R6234 T9334 T9354 themeOf NFAT,binding
R6233 T9333 T9353 themeOf NFIL-6,Role
R6235 T9335 T9353 causeOf TSST-1,Role
R6236 T9336 T9355 causeOf TSST-1,induced
R6237 T9337 T9356 themeOf IL-1RA,expression
R6238 T9339 T9358 themeOf IL-6,induced
R6239 T9340 T9358 causeOf IFNγ,induced
R6240 T9341 T9357 themeOf IL-1RA,bind
R6241 T9347 T9359 themeOf TSST-1,elevated
R6242 T9348 T9360 themeOf TSST-1,down-regulated
R6243 T9351 T9362 themeOf TSST-1,binding
R6244 T9356 T9355 themeOf expression,induced
R6245 T9362 T9361 themeOf binding,elevated
R6792 T10263 T10285 causeOf TSST-1,induced
R6793 T10264 T10284 themeOf IL-1β,modulated
R6794 T10264 T10285 themeOf IL-1β,induced
R6795 T10270 T10286 themeOf IL-1β,resulted
R6796 T10270 T10287 themeOf IL-1β,generating
R6797 T10277 T10288 themeOf IL-1RA,production
R6798 T10280 T10289 themeOf IL-2,release
R6799 T10285 T10284 themeOf induced,modulated
R11336 T16522 T16629 themeOf NFIL-6,binding
R11337 T16523 T16629 themeOf NFAT,binding
R17810 T26136 T26147 themeOf NFAT,Inhibition
R17812 T26137 T26147 themeOf NFIL-6,Inhibition
R17814 T26138 T26146 themeOf IL-1RA,binding
R17815 T26139 T26148 themeOf NFAT,resulted
R17816 T26140 T26148 themeOf NFIL-6,resulted
R17817 T26141 T26148 themeOf IL-1RA,resulted
R17818 T26141 T26149 themeOf IL-1RA,decreased
R17819 T26143 T26151 themeOf IL-1RA,production
R17820 T26144 T26150 themeOf NFAT,Inhibition
R17821 T26145 T26150 themeOf NFIL-6,Inhibition
R17822 T26151 T26152 themeOf production,reduced

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T24459 18903-18910 Positive_regulation denotes induced
T24458 18886-18895 Regulation denotes modulated
T24457 19648-19654 Protein denotes TSST-1
T24456 19609-19615 Protein denotes TSST-1
T24455 19379-19385 Protein denotes TSST-1
T24454 19300-19306 Protein denotes IL-1RA
T24453 19255-19259 Protein denotes NFAT
T24452 19177-19183 Protein denotes TSST-1
T24451 19160-19166 Protein denotes TSST-1
T24450 19085-19091 Protein denotes TSST-1
T24449 19017-19023 Protein denotes TSST-1
T24448 18953-18959 Protein denotes IL-1RA
T24447 18896-18902 Protein denotes TSST-1
T24003 18606-18613 Binding denotes Binding
T24002 18618-18626 Positive_regulation denotes enhanced
T24001 18546-18553 Positive_regulation denotes induced
T24000 18520-18529 Positive_regulation denotes modulated
T23999 18554-18561 Binding denotes binding
T23998 18710-18716 Protein denotes TSST-1
T23997 18679-18685 Protein denotes TSST-1
T23996 18649-18655 Protein denotes TSST-1
T23995 18589-18595 Protein denotes IL-1RA
T23994 18539-18545 Protein denotes TSST-1
T23390 13111-13121 Gene_expression denotes production
T23389 12861-12871 Gene_expression denotes production
T23388 12467-12476 Negative_regulation denotes reduction
T23387 12486-12496 Gene_expression denotes production
T23386 12497-12506 Positive_regulation denotes following
T23385 12303-12313 Gene_expression denotes production
T23384 12199-12213 Negative_regulation denotes down-regulated
T23383 13297-13303 Protein denotes IL-1RA
T23382 13270-13276 Protein denotes TSST-1
T23381 13176-13182 Protein denotes TSST-1
T23380 13104-13110 Protein denotes IL-1RA
T23379 13054-13060 Protein denotes TSST-1
T23378 12956-12962 Protein denotes TSST-1
T23377 12943-12949 Protein denotes TSST-1
T23376 12854-12860 Protein denotes IL-1RA
T23375 12824-12830 Protein denotes TSST-1
T23374 12786-12792 Protein denotes TSST-1
T23373 12748-12754 Protein denotes IL-1RA
T23372 12652-12657 Protein denotes IL-1β
T23371 12623-12629 Protein denotes TSST-1
T23370 12536-12542 Protein denotes TSST-1
T23369 12512-12518 Protein denotes TSST-1
T23368 12480-12485 Protein denotes IL-1β
T23367 12398-12404 Protein denotes TSST-1
T23366 12385-12391 Protein denotes TSST-1
T23365 12297-12302 Protein denotes IL-1β
T23364 12267-12273 Protein denotes TSST-1
T23363 12243-12249 Protein denotes TSST-1
T23362 12189-12194 Protein denotes IL-1β
T22607 10581-10589 Gene_expression denotes positive
T22606 10604-10607 Protein denotes p65
T22605 10599-10602 Protein denotes p50
T22604 10529-10534 Protein denotes c-rel
T22603 10524-10527 Protein denotes p52
T22602 10740-10742 Protein denotes c1
T22601 10731-10738 Protein denotes NFAT c2
T22600 10723-10726 Protein denotes p50
T22599 10718-10721 Protein denotes p65
T22598 10624-10626 Protein denotes c2
T22597 10616-10622 Protein denotes NFATc1
T22596 10379-10383 Protein denotes NFAT
T22595 10239-10241 Protein denotes c1
T22594 10232-10238 Protein denotes NFATc2
T22593 10224-10227 Protein denotes p50
T22592 10220-10223 Protein denotes p65
T21854 8987-8991 Protein denotes NFAT
T21878 9610-9617 Binding denotes binding
T21877 9596-9605 Negative_regulation denotes Decreased
T21876 8976-8983 Binding denotes binding
T21875 8965-8968 Positive_regulation denotes led
T21874 9947-9953 Protein denotes TSST-1
T21873 9765-9771 Protein denotes TSST-1
T21872 9739-9745 Protein denotes TSST-1
T21871 9676-9682 Protein denotes TSST-1
T21870 9661-9667 Protein denotes TSST-1
T21869 9641-9647 Protein denotes TSST-1
T21868 9506-9509 Protein denotes p50
T21867 9497-9500 Protein denotes p65
T21866 9483-9487 Protein denotes IL-8
T21865 9375-9379 Protein denotes IL-8
T21864 9356-9362 Protein denotes NFIL-6
T21863 9336-9340 Protein denotes NFAT
T21862 9241-9245 Protein denotes IL-8
T21861 9232-9236 Protein denotes IL-6
T21860 9226-9230 Protein denotes TNFα
T21859 9220-9224 Protein denotes IFNγ
T21858 9172-9176 Protein denotes IL-8
T21857 9157-9163 Protein denotes NFIL-6
T21856 9145-9149 Protein denotes NFAT
T21855 9002-9008 Protein denotes NFIL-6
T20591 38830-38837 Binding denotes binding
T20590 39932-39938 Protein denotes IL-1RA
T20589 39682-39687 Protein denotes GAPDH
T20588 39671-39677 Protein denotes IL-1RA
T20587 39489-39495 Protein denotes IL-1RA
T20586 39420-39421 Protein denotes 3
T20585 39413-39419 Protein denotes NFATP2
T20584 39360-39366 Protein denotes NFIL-6
T20583 38870-38876 Protein denotes IL-1RA
T21175 40720-40726 Protein denotes TSST-1
T21174 40707-40713 Protein denotes TSST-1
T21173 40435-40441 Protein denotes TSST-1
T21172 40422-40428 Protein denotes TSST-1
T19985 38342-38346 Protein denotes IL-1
T19984 38298-38302 Protein denotes IL-2
T19983 38228-38234 Protein denotes TGFβ 1
T19982 38156-38160 Protein denotes IL-8
T19981 38145-38151 Protein denotes IL-1RA
T19980 38070-38074 Protein denotes IL-6
T19979 38061-38065 Protein denotes IL-1
T19978 38055-38059 Protein denotes TNFα
T19977 38049-38053 Protein denotes IFNγ
T19376 37240-37246 Protein denotes NFATc1
T19375 37212-37218 Protein denotes NFATc2
T19374 37186-37191 Protein denotes c-rel
T19373 37127-37130 Protein denotes p52
T19372 37101-37104 Protein denotes p65
T19371 37073-37076 Protein denotes p50
T19370 36967-36972 Protein denotes c-Rel
T19369 36944-36947 Protein denotes p52
T19368 36686-36690 Protein denotes NFAT
T18968 36506-36511 Protein denotes Oct-1
T18967 36400-36402 Protein denotes 50
T18966 36396-36399 Protein denotes p65
T18490 35517-35524 Binding denotes binding
T18489 35501-35508 Positive_regulation denotes crucial
T18488 35528-35532 Protein denotes NFAT
T18487 35417-35421 Protein denotes TNFα
T18486 35359-35363 Protein denotes IFNγ
T18485 34889-34893 Protein denotes IL-6
T18484 34880-34884 Protein denotes IFNγ
T18483 34874-34878 Protein denotes IL-8
T18482 34868-34872 Protein denotes TNFα
T18079 34702-34708 Protein denotes TSST-1
T18078 34454-34460 Protein denotes TSST-1
T17266 32693-32702 Regulation denotes regulated
T17265 32595-32602 Binding denotes binding
T17264 32434-32441 Positive_regulation denotes induced
T17263 32271-32278 Positive_regulation denotes induced
T17262 32946-32952 Protein denotes IL-1RA
T17261 32940-32945 Protein denotes IL-1β
T17260 32654-32660 Protein denotes IL-1RA
T17259 32457-32463 Protein denotes IL-1RA
T17258 32427-32433 Protein denotes TSST-1
T17257 32377-32383 Protein denotes TSST-1
T14504 32010-32019 Positive_regulation denotes activated
T14503 31684-31694 Positive_regulation denotes activation
T14502 31608-31618 Gene_expression denotes production
T14501 31071-31078 Positive_regulation denotes induced
T14500 31052-31059 Negative_regulation denotes reduced
T14499 31085-31094 Positive_regulation denotes dependent
T14498 31100-31110 Gene_expression denotes production
T14497 30783-30789 Negative_regulation denotes excess
T14496 30840-30847 Regulation denotes effects
T14495 30652-30660 Negative_regulation denotes decrease
T14494 30516-30529 Positive_regulation denotes up-regulation
T14493 30544-30551 Positive_regulation denotes induced
T14492 30559-30569 Gene_expression denotes production
T14491 29312-29319 Positive_regulation denotes induced
T14490 29377-29390 Positive_regulation denotes up-regulation
T14488 29216-29225 Positive_regulation denotes increased
T14450 25100-25113 Transcription denotes transcription
T14449 25237-25248 Positive_regulation denotes GP-mediated
T14448 25082-25091 Positive_regulation denotes induction
T14447 25068-25075 Positive_regulation denotes pointed
T14446 25254-25267 Transcription denotes transcription
T14445 25127-25137 Positive_regulation denotes activation
T14444 24920-24927 Binding denotes binding
T14443 24896-24907 Positive_regulation denotes GP-mediated
T14442 24804-24814 Gene_expression denotes production
T14441 24758-24777 Positive_regulation denotes 3-D-glucan-mediated
T14440 24388-24395 Binding denotes binding
T14439 24441-24451 Positive_regulation denotes activation
T14438 24271-24278 Binding denotes binding
T14437 24263-24270 Positive_regulation denotes induced
T14436 32024-32030 Protein denotes IL-1RA
T14435 31698-31702 Protein denotes NFAT
T14434 31602-31607 Protein denotes IL-1β
T14433 31587-31593 Protein denotes IL-1RA
T14432 31362-31368 Protein denotes TSST-1
T14431 31346-31352 Protein denotes TSST-1
T14430 31064-31070 Protein denotes TSST-1
T14429 31095-31099 Protein denotes IL-2
T14428 31080-31084 Protein denotes IL-1
T14427 30993-30998 Protein denotes IL-1β
T14426 30919-30925 Protein denotes TSST-1
T14425 30891-30897 Protein denotes IL-1RA
T14424 30885-30890 Protein denotes IL-1β
T14423 30851-30855 Protein denotes IL-1
T14422 30805-30810 Protein denotes IL-1β
T14421 30793-30799 Protein denotes IL-1RA
T14420 30702-30708 Protein denotes TSST-1
T14419 30674-30680 Protein denotes IL-1RA
T14418 30668-30673 Protein denotes IL-1β
T14417 30552-30558 Protein denotes IL-1RA
T14416 30537-30543 Protein denotes TSST-1
T14415 30364-30370 Protein denotes TSST-1
T14414 30158-30164 Protein denotes TSST-1
T14413 29948-29954 Protein denotes IL-1RA
T14412 29647-29653 Protein denotes IL-1RA
T14411 29634-29638 Protein denotes TNFα
T14410 29432-29438 Protein denotes IL-1RA
T14409 29349-29353 Protein denotes TNFα
T14408 29305-29311 Protein denotes TSST-1
T14407 29149-29155 Protein denotes TSST-1
T14406 29096-29102 Protein denotes TSST-1
T14405 29068-29074 Protein denotes IL-1RA
T14404 28960-28966 Protein denotes IL-1RA
T14403 28945-28951 Protein denotes TSST-1
T14402 28869-28873 Protein denotes TNFα
T14401 28820-28826 Protein denotes TSST-1
T14400 28774-28778 Protein denotes IFNγ
T14399 28766-28770 Protein denotes IL-6
T14398 28759-28764 Protein denotes IL-1β
T14397 28753-28757 Protein denotes TNFα
T14396 28722-28728 Protein denotes IL-1RA
T14395 28713-28717 Protein denotes IL-8
T14394 28660-28664 Protein denotes NFAT
T14393 28649-28655 Protein denotes NFIL-6
T14392 28617-28623 Protein denotes TSST-1
T14391 28540-28546 Protein denotes IL-1RA
T14390 28476-28480 Protein denotes IL-6
T14389 28466-28471 Protein denotes IL-1β
T14388 28386-28392 Protein denotes IL-1RA
T14387 28380-28385 Protein denotes IL-1β
T14386 28365-28371 Protein denotes TSST-1
T14385 28201-28207 Protein denotes TSST-1
T14384 27682-27688 Protein denotes IL-1RA
T14383 27651-27655 Protein denotes IL-8
T14382 27548-27576 Protein denotes p38 mitogen-activated kinase
T14381 27512-27516 Protein denotes TNFα
T14380 27503-27507 Protein denotes IFNγ
T14379 27388-27394 Protein denotes TSST-1
T14378 27347-27351 Protein denotes TNFα
T14377 27222-27242 Protein denotes Toll-like receptor 4
T14376 27161-27167 Protein denotes TSST-1
T14375 27076-27082 Protein denotes TSST-1
T14374 26946-26952 Protein denotes IL-1RA
T14373 26933-26937 Protein denotes IL-8
T14372 26822-26828 Protein denotes IL-1RA
T14371 26708-26714 Protein denotes IL-1RA
T14370 26543-26549 Protein denotes IL-1RA
T14369 26513-26519 Protein denotes IL-1RA
T14368 26482-26488 Protein denotes NFIL-6
T14367 26473-26477 Protein denotes NFAT
T14366 26421-26427 Protein denotes IL-1RA
T14365 26412-26416 Protein denotes IL-6
T14364 26406-26410 Protein denotes IFNγ
T14363 26388-26392 Protein denotes NFAT
T14362 26254-26260 Protein denotes NFIL-6
T14361 26248-26249 Protein denotes 3
T14360 26241-26247 Protein denotes NFATP2
T14359 25923-25929 Protein denotes IL-1RA
T14358 25842-25848 Protein denotes IL-1RA
T14357 25811-25816 Protein denotes IL-1β
T14356 25771-25777 Protein denotes TSST-1
T14355 25583-25588 Protein denotes IL-1β
T14354 25574-25578 Protein denotes TNFα
T14353 25499-25502 Protein denotes p65
T14352 25451-25455 Protein denotes IL-8
T14351 25409-25413 Protein denotes IL-8
T14350 25381-25387 Protein denotes NFATc2
T14349 25363-25369 Protein denotes NFIL-6
T14348 25355-25358 Protein denotes p65
T14347 25283-25287 Protein denotes IL-8
T14346 25249-25253 Protein denotes IL-8
T14345 25188-25190 Protein denotes 50
T14344 25184-25187 Protein denotes p65
T14343 25154-25156 Protein denotes 65
T14342 25150-25153 Protein denotes p65
T14341 25095-25099 Protein denotes IL-8
T14340 24936-24939 Protein denotes p65
T14339 25000-25004 Protein denotes IL-8
T14338 24966-24969 Protein denotes p50
T14337 24797-24803 Protein denotes IL-1RA
T14336 24778-24782 Protein denotes IL-8
T14335 24668-24674 Protein denotes IL-1RA
T14334 24659-24663 Protein denotes IL-8
T14333 24473-24477 Protein denotes NFAT
T14332 24383-24387 Protein denotes NFAT
T14331 24301-24305 Protein denotes NFAT
T14330 24289-24295 Protein denotes NFIL-6
T10808 22780-22789 Negative_regulation denotes decreased
T10807 22797-22804 Localization denotes release
T10806 22448-22456 Negative_regulation denotes decrease
T10805 21994-22003 Negative_regulation denotes reduction
T10804 21741-21750 Positive_regulation denotes induction
T10803 21583-21590 Negative_regulation denotes reduced
T10802 21576-21579 Positive_regulation denotes led
T10801 22790-22796 Protein denotes IL-1RA
T10800 22572-22578 Protein denotes IL-1RA
T10799 22460-22466 Protein denotes IL-1RA
T10798 22319-22325 Protein denotes IL-1RA
T10797 22023-22029 Protein denotes IL-1RA
T10796 22007-22013 Protein denotes IL-1RA
T10795 21974-21980 Protein denotes IL-1RA
T10794 21843-21849 Protein denotes NFIL-6
T10793 21826-21830 Protein denotes NFAT
T10792 21754-21760 Protein denotes IL-1RA
T10791 21704-21710 Protein denotes IL-1RA
T10790 21591-21597 Protein denotes IL-1RA
T9914 20652-20659 Localization denotes release
T9913 20621-20629 Negative_regulation denotes decrease
T9912 20497-20507 Gene_expression denotes production
T9911 20490-20496 Positive_regulation denotes higher
T9910 20016-20020 Positive_regulation denotes more
T9909 20005-20015 Positive_regulation denotes generating
T9908 19993-20001 Positive_regulation denotes resulted
T9907 19682-19689 Positive_regulation denotes induced
T9906 19661-19670 Regulation denotes modulated
T9905 20743-20749 Protein denotes TSST-1
T9904 20730-20736 Protein denotes TSST-1
T9903 20706-20712 Protein denotes TSST-1
T9902 20663-20667 Protein denotes IL-2
T9901 20637-20641 Protein denotes IL-1
T9900 20526-20531 Protein denotes IL-1β
T9899 20511-20517 Protein denotes IL-1RA
T9898 20332-20338 Protein denotes TSST-1
T9897 20310-20316 Protein denotes TSST-1
T9896 20272-20278 Protein denotes TSST-1
T9895 20186-20192 Protein denotes IL-1RA
T9894 20180-20185 Protein denotes IL-1β
T9893 20032-20038 Protein denotes IL-1RA
T9892 20021-20026 Protein denotes IL-1β
T9891 19899-19905 Protein denotes IL-1RA
T9890 19893-19898 Protein denotes IL-1β
T9889 19784-19790 Protein denotes IL-1RA
T9888 19774-19779 Protein denotes IL-1β
T9887 19696-19702 Protein denotes IL-1RA
T9886 19690-19695 Protein denotes IL-1β
T9885 19675-19681 Protein denotes TSST-1
T8698 18348-18356 Positive_regulation denotes elevated
T8697 18222-18229 Binding denotes binding
T8696 17850-17859 Positive_regulation denotes increased
T8695 17839-17846 Positive_regulation denotes induced
T8694 17860-17867 Binding denotes binding
T8693 17547-17561 Negative_regulation denotes down-regulated
T8692 17405-17413 Positive_regulation denotes elevated
T8691 17328-17335 Binding denotes Binding
T8690 16340-16347 Positive_regulation denotes induced
T8689 16482-16486 Binding denotes bind
T8688 16202-16206 Positive_regulation denotes Role
T8687 16289-16296 Positive_regulation denotes induced
T8686 16304-16314 Gene_expression denotes expression
T8685 16232-16239 Binding denotes binding
T8684 18336-18342 Protein denotes TSST-1
T8683 18301-18307 Protein denotes TSST-1
T8682 17906-17912 Protein denotes TSST-1
T8681 17832-17838 Protein denotes TSST-1
T8680 17468-17474 Protein denotes TSST-1
T8679 17423-17429 Protein denotes TSST-1
T8678 17291-17297 Protein denotes TSST-1
T8677 17230-17236 Protein denotes TSST-1
T8676 17096-17102 Protein denotes TSST-1
T8675 17000-17006 Protein denotes TSST-1
T8674 16620-16626 Protein denotes IL-1RA
T8673 16503-16509 Protein denotes IL-1RA
T8672 16413-16417 Protein denotes IFNγ
T8671 16405-16409 Protein denotes IL-6
T8670 16399-16403 Protein denotes TNFα
T8669 16297-16303 Protein denotes IL-1RA
T8668 16282-16288 Protein denotes TSST-1
T8667 16249-16255 Protein denotes TSST-1
T8666 16227-16231 Protein denotes NFAT
T8665 16216-16222 Protein denotes NFIL-6
T6213 15958-15968 Gene_expression denotes production
T6212 16016-16023 Positive_regulation denotes induced
T6211 15708-15718 Gene_expression denotes production
T6210 15814-15823 Positive_regulation denotes following
T6209 15798-15813 Negative_regulation denotes down-regulation
T6208 15691-15699 Positive_regulation denotes increase
T6207 15603-15613 Gene_expression denotes production
T6206 15439-15445 Regulation denotes effect
T6205 15454-15463 Localization denotes secretion
T6204 15280-15286 Regulation denotes change
T6203 15296-15306 Gene_expression denotes production
T6202 15147-15157 Gene_expression denotes production
T6201 15009-15016 Positive_regulation denotes induced
T6200 14821-14832 Gene_expression denotes productions
T6199 14794-14804 Positive_regulation denotes GP-induced
T6198 14707-14714 Positive_regulation denotes induced
T6197 14687-14695 Positive_regulation denotes elevated
T6196 14492-14502 Gene_expression denotes production
T6195 14473-14481 Positive_regulation denotes increase
T6194 14407-14417 Gene_expression denotes production
T6193 14368-14373 Regulation denotes alter
T6192 14203-14211 Gene_expression denotes produced
T6191 14044-14053 Positive_regulation denotes following
T6190 14033-14043 Gene_expression denotes production
T6189 14014-14024 Regulation denotes alteration
T6188 13894-13902 Positive_regulation denotes resulted
T6187 13924-13932 Positive_regulation denotes increase
T6186 13941-13951 Gene_expression denotes production
T6185 13753-13760 Positive_regulation denotes induced
T6184 13780-13790 Gene_expression denotes production
T6183 13554-13563 Negative_regulation denotes decreased
T6182 13569-13579 Gene_expression denotes production
T6181 13405-13412 Positive_regulation denotes induced
T6180 13505-13515 Gene_expression denotes production
T6147 15291-15295 Protein denotes TNFα
T6146 15142-15146 Protein denotes TNFα
T6145 15121-15125 Protein denotes TNFα
T6144 15044-15050 Protein denotes IL-1RA
T6143 15035-15039 Protein denotes IL-8
T6142 14924-14930 Protein denotes IL-1RA
T6141 14915-14919 Protein denotes IL-8
T6140 14814-14820 Protein denotes IL-1RA
T6139 14805-14809 Protein denotes IL-8
T6138 14725-14731 Protein denotes IL-1RA
T6137 14700-14706 Protein denotes TSST-1
T6136 14620-14626 Protein denotes TSST-1
T6135 14539-14545 Protein denotes TSST-1
T6134 14485-14491 Protein denotes IL-1RA
T6133 14443-14449 Protein denotes TSST-1
T6132 14400-14406 Protein denotes IL-1RA
T6131 14164-14170 Protein denotes IL-1RA
T6130 14158-14162 Protein denotes IL-8
T6129 14143-14149 Protein denotes IL-1RA
T6128 14096-14102 Protein denotes TSST-1
T6127 14083-14089 Protein denotes TSST-1
T6126 14059-14065 Protein denotes TSST-1
T6125 14028-14032 Protein denotes IL-8
T6124 13936-13940 Protein denotes IL-8
T6123 13775-13779 Protein denotes IL-8
T6122 13731-13735 Protein denotes IL-8
T6121 13626-13632 Protein denotes TSST-1
T6120 13613-13619 Protein denotes TSST-1
T6119 13589-13595 Protein denotes TSST-1
T6118 13564-13568 Protein denotes IL-6
T6117 13500-13504 Protein denotes IL-6
T6116 13436-13440 Protein denotes IL-6
T6115 13397-13401 Protein denotes IL-6
T6114 12146-12151 Protein denotes IL-1β
T6113 12121-12127 Protein denotes TSST-1
T6112 12039-12045 Protein denotes TSST-1
T6111 12001-12007 Protein denotes TSST-1
T6110 11932-11937 Protein denotes IL-1β
T6109 11889-11895 Protein denotes TSST-1
T6108 11813-11818 Protein denotes IL-1β
T6107 11704-11709 Protein denotes IL-1β
T6106 11685-11690 Protein denotes IL-1β
T6105 11671-11677 Protein denotes TSST-1
T6104 11089-11093 Protein denotes IL-6
T6103 11083-11087 Protein denotes IL-8
T6102 11077-11081 Protein denotes TNFα
T6101 10981-10985 Protein denotes IFNγ
T6100 10972-10976 Protein denotes IL-6
T6099 10966-10970 Protein denotes IL-8
T6098 10960-10964 Protein denotes TNFα
T6097 11095-11099 Protein denotes IFNγ
T6096 10891-10897 Protein denotes TSST-1
T6095 10861-10867 Protein denotes TSST-1
T469 1477-1483 Protein denotes TSST-1
T470 1513-1519 Protein denotes NFIL-6
T471 1524-1528 Protein denotes NFAT
T472 1567-1573 Protein denotes IL-1RA
T473 1615-1621 Protein denotes TSST-1
T474 1669-1674 Protein denotes IL-1β
T475 1679-1683 Protein denotes IL-6
T476 1732-1738 Protein denotes TSST-1
T477 1747-1752 Protein denotes IL-1β
T478 1753-1759 Protein denotes IL-1RA
T479 1851-1857 Protein denotes TSST-1
T480 1867-1871 Protein denotes IL-1
T481 1896-1900 Protein denotes IL-2
T482 2102-2108 Protein denotes IL-1RA
T483 2199-2205 Protein denotes IL-1RA
T484 17-26 Regulation denotes modulates
T485 31-38 Binding denotes binding
T486 817-824 Positive_regulation denotes induced
T487 750-760 Gene_expression denotes production
T488 631-641 Positive_regulation denotes activation
T489 882-889 Positive_regulation denotes induced
T490 961-968 Binding denotes binding
T491 1062-1072 Gene_expression denotes production
T492 1022-1030 Positive_regulation denotes increase
T493 1212-1219 Binding denotes binding
T494 1192-1199 Positive_regulation denotes induced
T495 1496-1503 Binding denotes binding
T496 1484-1491 Positive_regulation denotes induced
T497 1451-1459 Positive_regulation denotes elevated
T498 1555-1563 Positive_regulation denotes increase
T499 1656-1665 Negative_regulation denotes reduction
T500 1622-1629 Positive_regulation denotes induced
T501 1739-1746 Positive_regulation denotes induced
T502 1858-1865 Positive_regulation denotes induced
T503 1882-1892 Gene_expression denotes production
T504 1837-1846 Negative_regulation denotes decreased
T505 1872-1881 Positive_regulation denotes dependent
T506 2181-2191 Regulation denotes regulation
T1932 2732-2740 Protein denotes Dectin-1
T1933 3007-3015 Protein denotes Dectin-1
T1934 3042-3046 Protein denotes TNFα
T1935 3055-3075 Protein denotes Toll-like receptor 2
T1936 3100-3105 Protein denotes MyD88
T1937 3202-3208 Protein denotes NFIL-6
T1938 3461-3465 Protein denotes IL-1
T1939 3467-3471 Protein denotes IL-6
T1940 3473-3477 Protein denotes TNFα
T1941 3549-3555 Protein denotes IL-1RA
T1942 3565-3569 Protein denotes IL-1
T1943 3771-3775 Protein denotes IL-8
T1944 4917-4923 Protein denotes TSST-1
T1945 5048-5052 Protein denotes TNFα
T1946 5054-5059 Protein denotes IL-1β
T1947 5061-5065 Protein denotes IL-6
T1948 5067-5071 Protein denotes IL-8
T1949 5076-5082 Protein denotes IL-1RA
T1950 5108-5112 Protein denotes IFNγ
T1951 5114-5118 Protein denotes IL-2
T1952 5120-5124 Protein denotes IL-4
T1953 5126-5131 Protein denotes IL-10
T1954 5133-5138 Protein denotes IL-12
T1955 5143-5148 Protein denotes TGFβ1
T1956 5192-5196 Protein denotes TNFα
T1957 5266-5270 Protein denotes IL-8
T1958 5308-5312 Protein denotes IFNγ
T1959 5371-5375 Protein denotes IL-6
T1960 5446-5452 Protein denotes IL-1RA
T1961 5508-5514 Protein denotes IL-1RA
T1962 5627-5633 Protein denotes IL-1RA
T1963 5822-5828 Protein denotes IL-1RA
T1964 2985-2992 Binding denotes binding
T1965 3016-3024 Positive_regulation denotes resulted
T1966 3028-3038 Gene_expression denotes production
T1967 3184-3192 Positive_regulation denotes activate
T1968 3420-3429 Gene_expression denotes secretion
T1969 3631-3638 Positive_regulation denotes induced
T1970 3513-3523 Gene_expression denotes production
T1971 3763-3770 Gene_expression denotes produce
T1972 5468-5475 Binding denotes binding
T3665 5877-5883 Protein denotes NFIL-6
T3666 5888-5892 Protein denotes NFAT
T3667 5916-5920 Protein denotes TNFα
T3668 5922-5926 Protein denotes IL-6
T3669 5931-5935 Protein denotes IFNγ
T3670 5996-6002 Protein denotes TSST-1
T3671 6026-6032 Protein denotes TSST-1
T3672 6223-6227 Protein denotes IL-8
T3673 6263-6267 Protein denotes IL-6
T3674 6098-6104 Protein denotes NFIL-6
T3675 6187-6191 Protein denotes TNFα
T3676 6397-6403 Protein denotes TSST-1
T3677 6475-6479 Protein denotes IL-8
T3678 6544-6547 Protein denotes p65
T3679 6574-6577 Protein denotes p50
T3680 6689-6692 Protein denotes p65
T3681 6718-6721 Protein denotes p50
T3682 6731-6734 Protein denotes p52
T3683 6863-6867 Protein denotes TNFα
T3684 6934-6940 Protein denotes TSST-1
T3685 6979-6985 Protein denotes TSST-1
T3686 7063-7069 Protein denotes TSST-1
T3687 7100-7106 Protein denotes TSST-1
T3688 7130-7136 Protein denotes TSST-1
T3689 7235-7239 Protein denotes NFAT
T3690 7261-7265 Protein denotes IFNγ
T3691 7308-7312 Protein denotes NFAT
T3692 7359-7365 Protein denotes NFATc2
T3693 7392-7398 Protein denotes NFATc1
T3694 5849-5856 Binding denotes Binding
T3695 5946-5955 Positive_regulation denotes following
T3696 6068-6075 Binding denotes binding
T3697 6505-6515 Positive_regulation denotes GP-induced
T3698 6528-6535 Binding denotes binding
T3699 6739-6747 Negative_regulation denotes negative
T3700 6673-6680 Binding denotes binding
T3701 7201-7208 Binding denotes binding
T3702 7337-7347 Positive_regulation denotes GP-induced
T3703 7348-7355 Binding denotes binding
T25824 23549-23556 Negative_regulation denotes reduced
T450 69-73 Protein denotes IL-6
T451 119-124 Protein denotes IL-1β
T452 125-149 Protein denotes IL-1 receptor antagonist
T453 572-600 Protein denotes toxic shock syndrome toxin 1
T454 602-608 Protein denotes TSST-1
T455 771-775 Protein denotes IL-6
T456 777-800 Protein denotes tumor necrosis factor α
T457 804-816 Protein denotes interferon γ
T458 668-687 Protein denotes NFinterleukin(IL)-6
T459 692-696 Protein denotes NFAT
T460 715-721 Protein denotes TSST-1
T461 764-769 Protein denotes IL-1β
T462 914-918 Protein denotes IL-8
T463 1004-1008 Protein denotes IL-8
T464 1034-1057 Protein denotes IL-1receptor antagonist
T465 1058-1060 Protein denotes RA
T466 1162-1166 Protein denotes IL-8
T467 1274-1280 Protein denotes IL-1RA
T468 1385-1391 Protein denotes TSST-1
T6179 13488-13499 Positive_regulation denotes LPS-induced
T6178 13470-13480 Regulation denotes alteration
T6177 12104-12113 Negative_regulation denotes reduction
T6176 12128-12135 Positive_regulation denotes induced
T6175 11919-11928 Negative_regulation denotes reduction
T6174 11819-11829 Gene_expression denotes production
T6173 11796-11809 Positive_regulation denotes up-regulation
T6172 11710-11720 Gene_expression denotes production
T6152 15598-15602 Protein denotes IFNγ
T6151 15590-15594 Protein denotes IFNγ
T6150 15449-15453 Protein denotes TNFα
T6149 15392-15398 Protein denotes TSST-1
T6148 15379-15385 Protein denotes TSST-1
T6171 11063-11073 Gene_expression denotes production
T6170 11055-11059 Positive_regulation denotes lead
T6169 16160-16166 Protein denotes TSST-1
T6168 16147-16153 Protein denotes TSST-1
T6167 16103-16109 Protein denotes TSST-1
T6166 16001-16007 Protein denotes TGFβ 1
T6165 15991-15996 Protein denotes IL-10
T6164 15985-15989 Protein denotes IL-4
T6163 15978-15983 Protein denotes IL-12
T6162 15972-15976 Protein denotes IL-2
T6161 15948-15953 Protein denotes TGFβ1
T6160 15941-15946 Protein denotes IL-10
T6159 15935-15939 Protein denotes IL-4
T6158 15928-15933 Protein denotes IL-12
T6157 15922-15926 Protein denotes IL-2
T6156 15884-15890 Protein denotes TSST-1
T6155 15871-15877 Protein denotes TSST-1
T6154 15829-15835 Protein denotes TSST-1
T6153 15703-15707 Protein denotes IFNγ
T25823 23499-23509 Negative_regulation denotes Inhibition
T25822 23364-23373 Negative_regulation denotes decreased
T14469 27301-27311 Gene_expression denotes expression
T14468 26925-26932 Gene_expression denotes produce
T14467 26814-26821 Gene_expression denotes produce
T14466 26489-26496 Binding denotes binding
T14465 26567-26574 Positive_regulation denotes induced
T14464 26455-26463 Negative_regulation denotes decrease
T14463 26695-26704 Positive_regulation denotes induction
T14462 26681-26690 Positive_regulation denotes necessary
T14461 26289-26292 Positive_regulation denotes due
T14460 26228-26237 Positive_regulation denotes induction
T14459 26265-26272 Binding denotes binding
T14458 26184-26189 Positive_regulation denotes leads
T14457 25804-25810 Positive_regulation denotes induce
T14456 25834-25841 Positive_regulation denotes induced
T14455 25288-25301 Transcription denotes transcription
T14454 25271-25282 Positive_regulation denotes GP-mediated
T14453 25394-25401 Binding denotes binding
T14452 25335-25349 Positive_regulation denotes transactivated
T14451 25371-25376 Positive_regulation denotes 13,39
T14489 29325-29332 Binding denotes binding
T14487 29120-29127 Binding denotes binding
T14486 29108-29119 Positive_regulation denotes LPS-induced
T14485 28952-28959 Positive_regulation denotes induced
T14484 28926-28937 Positive_regulation denotes enhancement
T14483 28835-28842 Binding denotes binding
T14482 28827-28834 Positive_regulation denotes induced
T14481 28967-28977 Gene_expression denotes production
T14480 28624-28631 Positive_regulation denotes induced
T14479 28598-28609 Regulation denotes modulations
T14478 28632-28639 Binding denotes binding
T14477 28523-28536 Positive_regulation denotes up-regulation
T14476 28353-28360 Regulation denotes altered
T14475 28447-28462 Negative_regulation denotes down-regulation
T14474 28372-28379 Positive_regulation denotes induced
T14473 27629-27650 Positive_regulation denotes neutrophil-attracting
T14472 27612-27621 Gene_expression denotes induction
T14471 27408-27415 Binding denotes binding
T14470 27485-27492 Localization denotes release
T24463 19264-19271 Binding denotes binding
T24462 19246-19254 Positive_regulation denotes elevated
T24461 18970-18977 Binding denotes Binding
T24460 18915-18922 Binding denotes binding
T25091 20827-20833 Protein denotes IL-1RA
T25090 20821-20826 Protein denotes IL-1β
T25107 21479-21484 Protein denotes IL-1β
T25106 21464-21470 Protein denotes IL-1RA
T25105 21300-21306 Protein denotes TSST-1
T25104 21279-21285 Protein denotes TSST-1
T25103 21266-21272 Protein denotes TSST-1
T25102 21226-21232 Protein denotes IL-1RA
T25101 21220-21225 Protein denotes IL-1β
T25100 21107-21113 Protein denotes IL-1RA
T25099 21096-21101 Protein denotes IL-1β
T25098 21027-21033 Protein denotes TSST-1
T25097 21014-21020 Protein denotes TSST-1
T25096 20977-20983 Protein denotes TSST-1
T25095 20919-20925 Protein denotes IL-1RA
T25094 20913-20918 Protein denotes IL-1β
T25093 20879-20885 Protein denotes TSST-1
T25092 20855-20861 Protein denotes TSST-1
T26235 27870-27876 Protein denotes IL-1RA
T25825 23561-23571 Gene_expression denotes production
T25821 23352-23360 Positive_regulation denotes resulted
T25820 22867-22874 Binding denotes binding
T25819 22816-22826 Negative_regulation denotes Inhibition
T25818 22830-22840 Positive_regulation denotes GP-induced
T25817 23528-23534 Protein denotes NFIL-6
T25816 23519-23523 Protein denotes NFAT
T25815 23575-23581 Protein denotes IL-1RA
T25814 23429-23434 Protein denotes GAPDH
T25813 23374-23380 Protein denotes IL-1RA
T25812 23345-23351 Protein denotes NFIL-6
T25811 23336-23340 Protein denotes NFAT
T25810 22882-22888 Protein denotes IL-1RA
T25809 22856-22862 Protein denotes NFIL-6
T25808 22847-22851 Protein denotes NFAT
T25114 21443-21449 Positive_regulation denotes higher
T25113 21450-21460 Gene_expression denotes production
T25112 21080-21090 Binding denotes generating
T25111 21091-21095 Positive_regulation denotes more
T25110 21068-21076 Positive_regulation denotes resulted
T25109 20811-20820 Negative_regulation denotes Decreased
T25108 20840-20849 Positive_regulation denotes following
R108 T469 T496 causeOf TSST-1,induced
R109 T469 T496 causeOf TSST-1,induced
R110 T470 T495 themeOf NFIL-6,binding
R111 T471 T495 themeOf NFAT,binding
R112 T472 T498 themeOf IL-1RA,increase
R120 T481 T503 themeOf IL-2,production
R121 T483 T506 themeOf IL-1RA,regulation
R122 T485 T484 themeOf binding,modulates
R123 T487 T486 themeOf production,induced
R124 T487 T486 themeOf production,induced
R125 T487 T486 themeOf production,induced
R126 T487 T486 themeOf production,induced
R127 T491 T492 themeOf production,increase
R128 T491 T492 themeOf production,increase
R129 T493 T494 themeOf binding,induced
R130 T495 T497 themeOf binding,elevated
R131 T495 T497 themeOf binding,elevated
R132 T495 T496 themeOf binding,induced
R133 T495 T496 themeOf binding,induced
R134 T503 T502 themeOf production,induced
R135 T503 T505 themeOf production,dependent
R136 T503 T504 themeOf production,decreased
R245 T450 T485 themeOf IL-6,binding
R246 T455 T487 themeOf IL-6,production
R247 T456 T487 themeOf tumor necrosis factor α,production
R248 T457 T487 themeOf interferon γ,production
R249 T457 T486 themeOf interferon γ,induced
R250 T458 T488 themeOf NFinterleukin(IL)-6,activation
R251 T459 T488 themeOf NFAT,activation
R252 T461 T487 themeOf IL-1β,production
R253 T461 T486 themeOf IL-1β,induced
R254 T462 T489 themeOf IL-8,induced
R255 T463 T490 themeOf IL-8,binding
R256 T464 T491 themeOf IL-1receptor antagonist,production
R257 T465 T491 themeOf RA,production
R258 T467 T493 themeOf IL-1RA,binding
R9442 T14347 T14455 themeOf IL-8,transcription
R9443 T14349 T14452 themeOf NFIL-6,transactivated
R9444 T14330 T14438 themeOf NFIL-6,binding
R9445 T14331 T14438 themeOf NFAT,binding
R9446 T14349 T14451 themeOf NFIL-6,"13,39"
R9447 T14349 T14453 themeOf NFIL-6,binding
R9448 T14350 T14453 themeOf NFATc2,binding
R9449 T14332 T14440 themeOf NFAT,binding
R9450 T14333 T14439 themeOf NFAT,activation
R9451 T14350 T14453 themeOf NFATc2,binding
R9452 T14336 T14442 themeOf IL-8,production
R9453 T14351 T14453 themeOf IL-8,binding
R9454 T14337 T14442 themeOf IL-1RA,production
R9455 T14357 T14457 themeOf IL-1β,induce
R9456 T14338 T14444 themeOf p50,binding
R9457 T14339 T14444 themeOf IL-8,binding
R9458 T14358 T14456 themeOf IL-1RA,induced
R9459 T14340 T14444 themeOf p65,binding
R9460 T14340 T14444 themeOf p65,binding
R9461 T14341 T14450 themeOf IL-8,transcription
R9462 T14360 T14460 themeOf NFATP2,induction
R9463 T14344 T14445 themeOf p65,activation
R9464 T14360 T14459 themeOf NFATP2,binding
R9465 T14346 T14446 themeOf IL-8,transcription
R9466 T14361 T14460 themeOf 3,induction
R9467 T14361 T14459 themeOf 3,binding
R9468 T14362 T14459 themeOf NFIL-6,binding
R9469 T14362 T14459 themeOf NFIL-6,binding
R9470 T14367 T14466 themeOf NFAT,binding
R9471 T14453 T14451 themeOf binding,"13,39"
R9472 T14453 T14451 themeOf binding,"13,39"
R9473 T14455 T14454 themeOf transcription,GP-mediated
R9474 T14367 T14466 themeOf NFAT,binding
R9475 T14459 T14460 themeOf binding,induction
R9476 T14459 T14460 themeOf binding,induction
R9477 T14460 T14458 themeOf induction,leads
R9478 T14460 T14458 themeOf induction,leads
R9479 T14460 T14458 themeOf induction,leads
R9480 T14460 T14458 themeOf induction,leads
R9481 T14460 T14461 themeOf induction,due
R9482 T14460 T14461 themeOf induction,due
R9483 T14460 T14461 themeOf induction,due
R9484 T14460 T14461 themeOf induction,due
R9485 T14367 T14465 themeOf NFAT,induced
R9486 T14463 T14462 themeOf induction,necessary
R9487 T14367 T14464 themeOf NFAT,decrease
R9488 T14368 T14466 themeOf NFIL-6,binding
R9489 T14368 T14466 themeOf NFIL-6,binding
R9490 T14368 T14465 themeOf NFIL-6,induced
R9491 T14368 T14464 themeOf NFIL-6,decrease
R9492 T14369 T14466 themeOf IL-1RA,binding
R9493 T14369 T14466 themeOf IL-1RA,binding
R9494 T14370 T14466 themeOf IL-1RA,binding
R9495 T14474 T14476 themeOf induced,altered
R9496 T14370 T14466 themeOf IL-1RA,binding
R9497 T14370 T14464 themeOf IL-1RA,decrease
R9498 T14371 T14463 themeOf IL-1RA,induction
R9499 T14372 T14467 themeOf IL-1RA,produce
R9500 T14478 T14479 themeOf binding,modulations
R9501 T14478 T14479 themeOf binding,modulations
R9502 T14478 T14479 themeOf binding,modulations
R9503 T14478 T14479 themeOf binding,modulations
R9504 T14478 T14479 themeOf binding,modulations
R9505 T14478 T14479 themeOf binding,modulations
R9506 T14373 T14468 themeOf IL-8,produce
R9507 T14478 T14479 themeOf binding,modulations
R9508 T14478 T14479 themeOf binding,modulations
R9509 T14478 T14479 themeOf binding,modulations
R9510 T14478 T14479 themeOf binding,modulations
R9511 T14478 T14479 themeOf binding,modulations
R9512 T14478 T14479 themeOf binding,modulations
R9513 T14478 T14480 themeOf binding,induced
R9514 T14478 T14480 themeOf binding,induced
R9515 T14478 T14480 themeOf binding,induced
R9516 T14478 T14480 themeOf binding,induced
R9517 T14478 T14480 themeOf binding,induced
R9518 T14478 T14480 themeOf binding,induced
R9519 T14478 T14480 themeOf binding,induced
R9520 T14478 T14480 themeOf binding,induced
R9521 T14478 T14480 themeOf binding,induced
R9522 T14478 T14480 themeOf binding,induced
R9523 T14478 T14480 themeOf binding,induced
R9524 T14478 T14480 themeOf binding,induced
R9525 T14481 T14484 themeOf production,enhancement
R9526 T14481 T14485 themeOf production,induced
R9527 T14483 T14482 themeOf binding,induced
R9528 T14378 T14469 themeOf TNFα,expression
R9529 T14487 T14486 themeOf binding,LPS-induced
R9530 T14379 T14471 themeOf TSST-1,binding
R9531 T14487 T14488 themeOf binding,increased
R9532 T14380 T14470 themeOf IFNγ,release
R9533 T14489 T14491 themeOf binding,induced
R9534 T14381 T14470 themeOf TNFα,release
R9535 T14492 T14494 themeOf production,up-regulation
R9536 T14492 T14493 themeOf production,induced
R9537 T14383 T14472 themeOf IL-8,induction
R9538 T14383 T14473 themeOf IL-8,neutrophil-attracting
R9539 T14498 T14499 themeOf production,dependent
R9540 T14498 T14500 themeOf production,reduced
R9541 T14498 T14501 themeOf production,induced
R9542 T14384 T14472 themeOf IL-1RA,induction
R9543 T14386 T14474 causeOf TSST-1,induced
R9544 T14387 T14474 themeOf IL-1β,induced
R9545 T14389 T14475 themeOf IL-1β,down-regulation
R9546 T14390 T14475 themeOf IL-6,down-regulation
R9548 T14391 T14477 themeOf IL-1RA,up-regulation
R9552 T14392 T14480 themeOf TSST-1,induced
R9554 T14393 T14478 themeOf NFIL-6,binding
R9556 T14393 T14478 themeOf NFIL-6,binding
R9557 T14393 T14478 themeOf NFIL-6,binding
R9559 T14393 T14478 themeOf NFIL-6,binding
R9561 T14393 T14478 themeOf NFIL-6,binding
R9564 T14393 T14478 themeOf NFIL-6,binding
R9565 T14394 T14478 themeOf NFAT,binding
R9567 T14394 T14478 themeOf NFAT,binding
R9570 T14394 T14478 themeOf NFAT,binding
R9574 T14394 T14478 themeOf NFAT,binding
R9576 T14394 T14478 themeOf NFAT,binding
R9577 T14394 T14478 themeOf NFAT,binding
R9579 T14395 T14478 themeOf IL-8,binding
R9580 T14395 T14478 themeOf IL-8,binding
R9581 T14396 T14478 themeOf IL-1RA,binding
R9584 T14396 T14478 themeOf IL-1RA,binding
R9587 T14397 T14478 themeOf TNFα,binding
R9590 T14397 T14478 themeOf TNFα,binding
R9591 T14398 T14478 themeOf IL-1β,binding
R9592 T14398 T14478 themeOf IL-1β,binding
R9593 T14399 T14478 themeOf IL-6,binding
R9594 T14399 T14478 themeOf IL-6,binding
R9595 T14400 T14478 themeOf IFNγ,binding
R9596 T14400 T14478 themeOf IFNγ,binding
R9599 T14401 T14482 causeOf TSST-1,induced
R9602 T14402 T14483 themeOf TNFα,binding
R9605 T14403 T14485 causeOf TSST-1,induced
R9607 T14404 T14481 themeOf IL-1RA,production
R9611 T14406 T14486 themeOf TSST-1,LPS-induced
R9616 T14406 T14487 themeOf TSST-1,binding
R9617 T14408 T14491 causeOf TSST-1,induced
R9621 T14409 T14489 themeOf TNFα,binding
R9625 T14410 T14490 themeOf IL-1RA,up-regulation
R9628 T14416 T14493 causeOf TSST-1,induced
R9632 T14417 T14492 themeOf IL-1RA,production
R9635 T14419 T14495 themeOf IL-1RA,decrease
R9636 T14421 T14497 themeOf IL-1RA,excess
R9641 T14422 T14497 themeOf IL-1β,excess
R9643 T14423 T14496 themeOf IL-1,effects
R9645 T14428 T14499 causeOf IL-1,dependent
R9652 T14429 T14498 themeOf IL-2,production
R9653 T14430 T14501 causeOf TSST-1,induced
R9656 T14434 T14502 themeOf IL-1β,production
R9661 T14435 T14503 themeOf NFAT,activation
R9662 T14436 T14504 themeOf IL-1RA,activated
R9666 T14438 T14437 themeOf binding,induced
R9671 T14438 T14437 themeOf binding,induced
R9674 T14442 T14441 themeOf production,3-D-glucan-mediated
R9676 T14442 T14441 themeOf production,3-D-glucan-mediated
R9678 T14444 T14443 themeOf binding,GP-mediated
R9679 T14444 T14443 themeOf binding,GP-mediated
R9682 T14446 T14449 themeOf transcription,GP-mediated
R9685 T14448 T14447 themeOf induction,pointed
R9689 T14450 T14448 themeOf transcription,induction
R11624 T17257 T17263 themeOf TSST-1,induced
R11625 T17258 T17264 themeOf TSST-1,induced
R11626 T17260 T17265 themeOf IL-1RA,binding
R11627 T17260 T17266 themeOf IL-1RA,regulated
R12655 T18488 T18490 themeOf NFAT,binding
R12656 T18490 T18489 themeOf binding,crucial
R14139 T20583 T20591 themeOf IL-1RA,binding
R15021 T21854 T21876 themeOf NFAT,binding
R15022 T21855 T21876 themeOf NFIL-6,binding
R15023 T21869 T21878 themeOf TSST-1,binding
R15024 T21876 T21875 themeOf binding,led
R15025 T21876 T21875 themeOf binding,led
R15026 T21878 T21877 themeOf binding,Decreased
R15455 T22597 T22607 themeOf NFATc1,positive
R15456 T22605 T22607 themeOf p50,positive
R15457 T22606 T22607 themeOf p65,positive
R15922 T23362 T23384 themeOf IL-1β,down-regulated
R15923 T23365 T23385 themeOf IL-1β,production
R15924 T23368 T23387 themeOf IL-1β,production
R15925 T23376 T23389 themeOf IL-1RA,production
R15926 T23380 T23390 themeOf IL-1RA,production
R15927 T23387 T23388 themeOf production,reduction
R15928 T23387 T23386 themeOf production,following
R16341 T23994 T24001 causeOf TSST-1,induced
R16342 T23995 T23999 themeOf IL-1RA,binding
R16343 T23997 T24003 themeOf TSST-1,Binding
R16344 T23999 T24000 themeOf binding,modulated
R16345 T23999 T24001 themeOf binding,induced
R16346 T24001 T24000 themeOf induced,modulated
R16347 T24003 T24002 themeOf Binding,enhanced
R16649 T24447 T24459 causeOf TSST-1,induced
R16650 T24448 T24460 themeOf IL-1RA,binding
R16651 T24450 T24461 themeOf TSST-1,Binding
R16652 T24453 T24462 themeOf NFAT,elevated
R16653 T24453 T24463 themeOf NFAT,binding
R16654 T24459 T24458 themeOf induced,modulated
R16655 T24460 T24458 themeOf binding,modulated
R16656 T24460 T24459 themeOf binding,induced
R17040 T25090 T25109 themeOf IL-1β,Decreased
R17041 T25092 T25108 themeOf TSST-1,following
R17042 T25099 T25112 themeOf IL-1β,generating
R17043 T25099 T25111 themeOf IL-1β,more
R17044 T25106 T25113 themeOf IL-1RA,production
R17045 T25112 T25110 themeOf generating,resulted
R17046 T25113 T25114 themeOf production,higher
R17523 T25808 T25820 themeOf NFAT,binding
R17524 T25808 T25819 themeOf NFAT,Inhibition
R17525 T25809 T25820 themeOf NFIL-6,binding
R17526 T25809 T25819 themeOf NFIL-6,Inhibition
R17527 T25809 T25818 themeOf NFIL-6,GP-induced
R17528 T25810 T25820 themeOf IL-1RA,binding
R17529 T25810 T25820 themeOf IL-1RA,binding
R17530 T25811 T25821 themeOf NFAT,resulted
R17531 T25811 T25822 causeOf NFAT,decreased
R17532 T25812 T25821 themeOf NFIL-6,resulted
R17533 T25812 T25822 causeOf NFIL-6,decreased
R17534 T25813 T25822 themeOf IL-1RA,decreased
R17535 T25813 T25822 themeOf IL-1RA,decreased
R17536 T25815 T25825 themeOf IL-1RA,production
R17537 T25816 T25824 causeOf NFAT,reduced
R17538 T25816 T25823 themeOf NFAT,Inhibition
R17539 T25817 T25823 themeOf NFIL-6,Inhibition
R17540 T25817 T25824 causeOf NFIL-6,reduced
R17541 T25823 T25824 causeOf Inhibition,reduced
R17542 T25823 T25824 causeOf Inhibition,reduced
R17543 T25825 T25824 themeOf production,reduced
R17544 T25825 T25824 themeOf production,reduced
R17545 T25825 T25824 themeOf production,reduced
R17546 T25825 T25824 themeOf production,reduced
R1050 T1933 T1964 themeOf Dectin-1,binding
R1051 T1934 T1966 themeOf TNFα,production
R1052 T1937 T1967 themeOf NFIL-6,activate
R1053 T1938 T1968 themeOf IL-1,secretion
R1054 T1939 T1968 themeOf IL-6,secretion
R1055 T1940 T1968 themeOf TNFα,secretion
R1056 T1941 T1970 themeOf IL-1RA,production
R1057 T1942 T1969 themeOf IL-1,induced
R1058 T1942 T1970 themeOf IL-1,production
R1059 T1943 T1971 themeOf IL-8,produce
R1060 T1961 T1972 themeOf IL-1RA,binding
R1061 T1964 T1965 causeOf binding,resulted
R1062 T1966 T1965 themeOf production,resulted
R1063 T1970 T1969 themeOf production,induced
R1064 T1970 T1969 themeOf production,induced
R2264 T3665 T3695 themeOf NFIL-6,following
R2265 T3665 T3694 themeOf NFIL-6,Binding
R2266 T3666 T3694 themeOf NFAT,Binding
R2267 T3668 T3694 themeOf IL-6,Binding
R2268 T3672 T3696 themeOf IL-8,binding
R2269 T3673 T3696 themeOf IL-6,binding
R2270 T3674 T3696 themeOf NFIL-6,binding
R2271 T3674 T3696 themeOf NFIL-6,binding
R2272 T3674 T3696 themeOf NFIL-6,binding
R2273 T3675 T3696 themeOf TNFα,binding
R2274 T3678 T3698 themeOf p65,binding
R2275 T3679 T3698 themeOf p50,binding
R2276 T3680 T3700 themeOf p65,binding
R2277 T3682 T3699 themeOf p52,negative
R2278 T3689 T3701 themeOf NFAT,binding
R2279 T3692 T3703 themeOf NFATc2,binding
R2280 T3693 T3703 themeOf NFATc1,binding
R2281 T3698 T3697 themeOf binding,GP-induced
R2282 T3703 T3702 themeOf binding,GP-induced
R3806 T6097 T6171 themeOf IFNγ,production
R3807 T6102 T6171 themeOf TNFα,production
R3808 T6103 T6171 themeOf IL-8,production
R3809 T6104 T6171 themeOf IL-6,production
R3810 T6107 T6172 themeOf IL-1β,production
R3811 T6108 T6174 themeOf IL-1β,production
R3812 T6110 T6175 themeOf IL-1β,reduction
R3813 T6113 T6176 causeOf TSST-1,induced
R3814 T6114 T6176 themeOf IL-1β,induced
R3815 T6114 T6177 themeOf IL-1β,reduction
R3816 T6150 T6205 themeOf TNFα,secretion
R3817 T6116 T6181 themeOf IL-6,induced
R3818 T6152 T6207 themeOf IFNγ,production
R3819 T6153 T6211 themeOf IFNγ,production
R3820 T6117 T6180 themeOf IL-6,production
R3821 T6154 T6209 themeOf TSST-1,down-regulation
R3822 T6118 T6182 themeOf IL-6,production
R3823 T6119 T6182 themeOf TSST-1,production
R3824 T6162 T6213 themeOf IL-2,production
R3825 T6163 T6213 themeOf IL-12,production
R3826 T6123 T6184 themeOf IL-8,production
R3827 T6164 T6213 themeOf IL-4,production
R3828 T6165 T6213 themeOf IL-10,production
R3829 T6166 T6213 themeOf TGFβ 1,production
R3830 T6124 T6186 themeOf IL-8,production
R3831 T6171 T6170 themeOf production,lead
R3832 T6125 T6190 themeOf IL-8,production
R3833 T6171 T6170 themeOf production,lead
R3834 T6126 T6190 themeOf TSST-1,production
R3835 T6171 T6170 themeOf production,lead
R3836 T6130 T6192 themeOf IL-8,produced
R3837 T6171 T6170 themeOf production,lead
R3838 T6174 T6173 themeOf production,up-regulation
R3839 T6132 T6194 themeOf IL-1RA,production
R3840 T6176 T6177 themeOf induced,reduction
R3841 T6134 T6196 themeOf IL-1RA,production
R3842 T6179 T6178 themeOf LPS-induced,alteration
R3843 T6180 T6178 themeOf production,alteration
R3844 T6180 T6179 themeOf production,LPS-induced
R3845 T6137 T6198 causeOf TSST-1,induced
R3846 T6182 T6183 themeOf production,decreased
R3847 T6182 T6183 themeOf production,decreased
R3848 T6184 T6185 themeOf production,induced
R3849 T6138 T6197 themeOf IL-1RA,elevated
R3850 T6186 T6187 themeOf production,increase
R3851 T6187 T6188 themeOf increase,resulted
R3852 T6138 T6198 themeOf IL-1RA,induced
R3853 T6139 T6199 themeOf IL-8,GP-induced
R3854 T6190 T6191 themeOf production,following
R3855 T6190 T6191 themeOf production,following
R3856 T6190 T6189 themeOf production,alteration
R3857 T6190 T6189 themeOf production,alteration
R3858 T6139 T6200 themeOf IL-8,productions
R3859 T6143 T6201 themeOf IL-8,induced
R3860 T6194 T6193 themeOf production,alter
R3861 T6196 T6195 themeOf production,increase
R3862 T6198 T6197 themeOf induced,elevated
R3863 T6144 T6201 themeOf IL-1RA,induced
R3864 T6146 T6202 themeOf TNFα,production
R3865 T6203 T6204 themeOf production,change
R3866 T6205 T6206 themeOf secretion,effect
R3867 T6147 T6203 themeOf TNFα,production
R3868 T6213 T6212 themeOf production,induced
R3869 T6213 T6212 themeOf production,induced
R3870 T6211 T6210 themeOf production,following
R3871 T6211 T6208 themeOf production,increase
R3872 T6213 T6212 themeOf production,induced
R3873 T6213 T6212 themeOf production,induced
R3874 T6213 T6212 themeOf production,induced
R5633 T8665 T8685 themeOf NFIL-6,binding
R5634 T8665 T8687 causeOf NFIL-6,induced
R5635 T8665 T8687 causeOf NFIL-6,induced
R5636 T8665 T8686 themeOf NFIL-6,expression
R5637 T8665 T8688 causeOf NFIL-6,Role
R5638 T8666 T8685 themeOf NFAT,binding
R5639 T8667 T8688 causeOf TSST-1,Role
R5640 T8668 T8687 causeOf TSST-1,induced
R5641 T8668 T8687 causeOf TSST-1,induced
R5642 T8669 T8686 themeOf IL-1RA,expression
R5643 T8670 T8690 themeOf TNFα,induced
R5644 T8671 T8690 themeOf IL-6,induced
R5645 T8672 T8690 themeOf IFNγ,induced
R5646 T8673 T8689 themeOf IL-1RA,bind
R5647 T8679 T8691 themeOf TSST-1,Binding
R5648 T8679 T8692 themeOf TSST-1,elevated
R5649 T8680 T8693 themeOf TSST-1,down-regulated
R5650 T8681 T8695 causeOf TSST-1,induced
R5651 T8682 T8694 themeOf TSST-1,binding
R5652 T8683 T8697 themeOf TSST-1,binding
R5653 T8685 T8688 themeOf binding,Role
R5654 T8685 T8688 themeOf binding,Role
R5655 T8686 T8687 themeOf expression,induced
R5656 T8686 T8687 themeOf expression,induced
R5657 T8686 T8687 themeOf expression,induced
R5658 T8686 T8687 themeOf expression,induced
R5659 T8694 T8695 themeOf binding,induced
R5660 T8694 T8696 themeOf binding,increased
R5661 T8697 T8698 themeOf binding,elevated
R6523 T9885 T9907 causeOf TSST-1,induced
R6524 T9886 T9907 themeOf IL-1β,induced
R6525 T9892 T9909 themeOf IL-1β,generating
R6526 T9892 T9910 themeOf IL-1β,more
R6527 T9899 T9912 themeOf IL-1RA,production
R6528 T9902 T9914 themeOf IL-2,release
R6529 T9907 T9906 themeOf induced,modulated
R6530 T9909 T9908 themeOf generating,resulted
R6531 T9912 T9911 themeOf production,higher
R6532 T9914 T9913 themeOf release,decrease
R7107 T10790 T10802 themeOf IL-1RA,led
R7108 T10790 T10803 themeOf IL-1RA,reduced
R7109 T10792 T10804 themeOf IL-1RA,induction
R7110 T10796 T10805 themeOf IL-1RA,reduction
R7111 T10797 T10805 themeOf IL-1RA,reduction
R7112 T10799 T10806 themeOf IL-1RA,decrease
R7113 T10801 T10807 themeOf IL-1RA,release
R7114 T10807 T10808 themeOf release,decreased
R113 T473 T500 themeOf TSST-1,induced
R114 T474 T499 themeOf IL-1β,reduction
R115 T475 T499 themeOf IL-6,reduction
R116 T476 T501 causeOf TSST-1,induced
R117 T477 T501 themeOf IL-1β,induced
R118 T479 T502 causeOf TSST-1,induced
R119 T480 T505 causeOf IL-1,dependent

DLUT931

Id Subject Object Predicate Lexical cue
T24480 19246-19254 Positive_regulation denotes elevated
T24479 19264-19271 Binding denotes binding
T24478 18982-18994 Positive_regulation denotes up-regulated
T24477 18970-18977 Binding denotes Binding
T24476 18903-18910 Positive_regulation denotes induced
T24475 18915-18922 Binding denotes binding
T24474 19648-19654 Protein denotes TSST-1
T24473 19609-19615 Protein denotes TSST-1
T24472 19379-19385 Protein denotes TSST-1
T24471 19300-19306 Protein denotes IL-1RA
T24470 19255-19259 Protein denotes NFAT
T24469 19177-19183 Protein denotes TSST-1
T24468 19160-19166 Protein denotes TSST-1
T24467 19085-19091 Protein denotes TSST-1
T24466 19017-19023 Protein denotes TSST-1
T24465 18953-18959 Protein denotes IL-1RA
T24464 18896-18902 Protein denotes TSST-1
T24015 18546-18553 Positive_regulation denotes induced
T24014 18554-18561 Binding denotes binding
T24013 18710-18716 Protein denotes TSST-1
T24012 18679-18685 Protein denotes TSST-1
T24011 18649-18655 Protein denotes TSST-1
T24010 18589-18595 Protein denotes IL-1RA
T24009 18539-18545 Protein denotes TSST-1
T25118 20879-20885 Protein denotes TSST-1
T25117 20855-20861 Protein denotes TSST-1
T25116 20827-20833 Protein denotes IL-1RA
T25115 20821-20826 Protein denotes IL-1β
T23418 13111-13121 Gene_expression denotes production
T23417 12861-12871 Gene_expression denotes production
T23416 12467-12476 Negative_regulation denotes reduction
T23415 12497-12506 Positive_regulation denotes following
T23414 12486-12496 Gene_expression denotes production
T23413 12303-12313 Gene_expression denotes production
T23412 13297-13303 Protein denotes IL-1RA
T23411 13270-13276 Protein denotes TSST-1
T23410 13176-13182 Protein denotes TSST-1
T23409 13104-13110 Protein denotes IL-1RA
T23408 13054-13060 Protein denotes TSST-1
T23407 12956-12962 Protein denotes TSST-1
T23406 12943-12949 Protein denotes TSST-1
T23405 12854-12860 Protein denotes IL-1RA
T23404 12824-12830 Protein denotes TSST-1
T23403 12786-12792 Protein denotes TSST-1
T23402 12748-12754 Protein denotes IL-1RA
T23401 12652-12657 Protein denotes IL-1β
T23400 12623-12629 Protein denotes TSST-1
T23399 12536-12542 Protein denotes TSST-1
T23398 12512-12518 Protein denotes TSST-1
T23397 12480-12485 Protein denotes IL-1β
T23396 12398-12404 Protein denotes TSST-1
T23395 12385-12391 Protein denotes TSST-1
T23394 12297-12302 Protein denotes IL-1β
T23393 12267-12273 Protein denotes TSST-1
T23392 12243-12249 Protein denotes TSST-1
T23391 12189-12194 Protein denotes IL-1β
T22625 10700-10708 Gene_expression denotes positive
T22624 10581-10589 Gene_expression denotes positive
T22623 10274-10281 Binding denotes binding
T22622 10604-10607 Protein denotes p65
T22621 10599-10602 Protein denotes p50
T22620 10529-10534 Protein denotes c-rel
T22619 10524-10527 Protein denotes p52
T22618 10740-10742 Protein denotes c1
T22617 10731-10738 Protein denotes NFAT c2
T22616 10723-10726 Protein denotes p50
T22615 10718-10721 Protein denotes p65
T22614 10624-10626 Protein denotes c2
T22613 10616-10622 Protein denotes NFATc1
T22612 10379-10383 Protein denotes NFAT
T22611 10239-10241 Protein denotes c1
T22610 10232-10238 Protein denotes NFATc2
T22609 10224-10227 Protein denotes p50
T22608 10220-10223 Protein denotes p65
T21904 9596-9605 Negative_regulation denotes Decreased
T21903 9610-9617 Binding denotes binding
T21902 9199-9212 Positive_regulation denotes corresponding
T21901 8965-8968 Positive_regulation denotes led
T21900 8976-8983 Binding denotes binding
T21899 9947-9953 Protein denotes TSST-1
T21898 9765-9771 Protein denotes TSST-1
T21897 9739-9745 Protein denotes TSST-1
T21896 9676-9682 Protein denotes TSST-1
T21895 9661-9667 Protein denotes TSST-1
T21894 9641-9647 Protein denotes TSST-1
T21893 9506-9509 Protein denotes p50
T21892 9497-9500 Protein denotes p65
T21891 9483-9487 Protein denotes IL-8
T21890 9375-9379 Protein denotes IL-8
T21889 9356-9362 Protein denotes NFIL-6
T21888 9336-9340 Protein denotes NFAT
T21887 9241-9245 Protein denotes IL-8
T21886 9232-9236 Protein denotes IL-6
T21885 9226-9230 Protein denotes TNFα
T21884 9220-9224 Protein denotes IFNγ
T21883 9172-9176 Protein denotes IL-8
T21882 9157-9163 Protein denotes NFIL-6
T21881 9145-9149 Protein denotes NFAT
T21880 9002-9008 Protein denotes NFIL-6
T21879 8987-8991 Protein denotes NFAT
T20601 39464-39471 Binding denotes binding
T20600 38830-38837 Binding denotes binding
T20599 39932-39938 Protein denotes IL-1RA
T20598 39682-39687 Protein denotes GAPDH
T20597 39671-39677 Protein denotes IL-1RA
T20596 39489-39495 Protein denotes IL-1RA
T20595 39420-39421 Protein denotes 3
T20594 39413-39419 Protein denotes NFATP2
T20593 39360-39366 Protein denotes NFIL-6
T20592 38870-38876 Protein denotes IL-1RA
T20003 38342-38346 Protein denotes IL-1
T20002 38298-38302 Protein denotes IL-2
T20001 38228-38234 Protein denotes TGFβ 1
T20000 38156-38160 Protein denotes IL-8
T19999 38145-38151 Protein denotes IL-1RA
T19998 38070-38074 Protein denotes IL-6
T19997 38061-38065 Protein denotes IL-1
T19996 38055-38059 Protein denotes TNFα
T19995 38049-38053 Protein denotes IFNγ
T19385 37240-37246 Protein denotes NFATc1
T19384 37212-37218 Protein denotes NFATc2
T19383 37186-37191 Protein denotes c-rel
T19382 37127-37130 Protein denotes p52
T19381 37101-37104 Protein denotes p65
T19380 37073-37076 Protein denotes p50
T19379 36967-36972 Protein denotes c-Rel
T19378 36944-36947 Protein denotes p52
T19377 36686-36690 Protein denotes NFAT
T18979 36587-36594 Binding denotes binding
T18978 36496-36502 Negative_regulation denotes excess
T18977 36506-36511 Protein denotes Oct-1
T18976 36400-36402 Protein denotes 50
T18975 36396-36399 Protein denotes p65
T18521 35501-35508 Positive_regulation denotes crucial
T18520 35517-35524 Binding denotes binding
T18519 35528-35532 Protein denotes NFAT
T18518 35417-35421 Protein denotes TNFα
T18517 35359-35363 Protein denotes IFNγ
T18516 34889-34893 Protein denotes IL-6
T18515 34880-34884 Protein denotes IFNγ
T18514 34874-34878 Protein denotes IL-8
T18513 34868-34872 Protein denotes TNFα
T18083 34702-34708 Protein denotes TSST-1
T18082 34454-34460 Protein denotes TSST-1
T17286 32946-32952 Protein denotes IL-1RA
T17285 32940-32945 Protein denotes IL-1β
T17284 32654-32660 Protein denotes IL-1RA
T17283 32457-32463 Protein denotes IL-1RA
T17282 32427-32433 Protein denotes TSST-1
T17281 32377-32383 Protein denotes TSST-1
T17289 32927-32939 Positive_regulation denotes dysregulated
T17288 32693-32702 Regulation denotes regulated
T17287 32595-32602 Binding denotes binding
T14559 27682-27688 Protein denotes IL-1RA
T14558 27651-27655 Protein denotes IL-8
T14557 27548-27576 Protein denotes p38 mitogen-activated kinase
T14556 27512-27516 Protein denotes TNFα
T14555 27503-27507 Protein denotes IFNγ
T14554 27388-27394 Protein denotes TSST-1
T14553 27347-27351 Protein denotes TNFα
T14552 27222-27242 Protein denotes Toll-like receptor 4
T14551 27161-27167 Protein denotes TSST-1
T14550 27076-27082 Protein denotes TSST-1
T14549 26946-26952 Protein denotes IL-1RA
T14548 26933-26937 Protein denotes IL-8
T14547 26822-26828 Protein denotes IL-1RA
T14546 26708-26714 Protein denotes IL-1RA
T14545 26543-26549 Protein denotes IL-1RA
T14544 26513-26519 Protein denotes IL-1RA
T14543 26482-26488 Protein denotes NFIL-6
T14540 26412-26416 Protein denotes IL-6
T14539 26406-26410 Protein denotes IFNγ
T14538 26388-26392 Protein denotes NFAT
T14537 26254-26260 Protein denotes NFIL-6
T14536 26248-26249 Protein denotes 3
T14535 26241-26247 Protein denotes NFATP2
T14534 25923-25929 Protein denotes IL-1RA
T14533 25842-25848 Protein denotes IL-1RA
T14532 25811-25816 Protein denotes IL-1β
T14531 25771-25777 Protein denotes TSST-1
T14530 25583-25588 Protein denotes IL-1β
T14529 25574-25578 Protein denotes TNFα
T14528 25499-25502 Protein denotes p65
T14527 25451-25455 Protein denotes IL-8
T14526 25409-25413 Protein denotes IL-8
T14525 25381-25387 Protein denotes NFATc2
T14524 25363-25369 Protein denotes NFIL-6
T14523 25355-25358 Protein denotes p65
T14522 25283-25287 Protein denotes IL-8
T14521 25249-25253 Protein denotes IL-8
T14520 25188-25190 Protein denotes 50
T14519 25184-25187 Protein denotes p65
T14518 25154-25156 Protein denotes 65
T14517 25150-25153 Protein denotes p65
T14516 25095-25099 Protein denotes IL-8
T14515 24936-24939 Protein denotes p65
T14514 25000-25004 Protein denotes IL-8
T14513 24966-24969 Protein denotes p50
T14512 24797-24803 Protein denotes IL-1RA
T14511 24778-24782 Protein denotes IL-8
T14510 24668-24674 Protein denotes IL-1RA
T14509 24659-24663 Protein denotes IL-8
T14508 24473-24477 Protein denotes NFAT
T14507 24383-24387 Protein denotes NFAT
T14506 24301-24305 Protein denotes NFAT
T14505 24289-24295 Protein denotes NFIL-6
T14686 32010-32019 Positive_regulation denotes activated
T14685 31668-31676 Regulation denotes involved
T14684 31684-31694 Positive_regulation denotes activation
T14683 31577-31585 Regulation denotes controls
T14682 31608-31618 Gene_expression denotes production
T14681 31052-31059 Negative_regulation denotes reduced
T14680 31071-31078 Positive_regulation denotes induced
T14679 31100-31110 Gene_expression denotes production
T14678 30840-30847 Regulation denotes effects
T14677 30783-30789 Negative_regulation denotes excess
T14676 30652-30660 Negative_regulation denotes decrease
T14675 30516-30529 Positive_regulation denotes up-regulation
T14674 30544-30551 Positive_regulation denotes induced
T14673 30559-30569 Gene_expression denotes production
T14672 29608-29615 Binding denotes binding
T14671 29312-29319 Positive_regulation denotes induced
T14670 29377-29390 Positive_regulation denotes up-regulation
T14669 29325-29332 Binding denotes binding
T14668 29108-29119 Positive_regulation denotes LPS-induced
T14667 29216-29225 Positive_regulation denotes increased
T14666 29120-29127 Binding denotes binding
T14665 28926-28937 Positive_regulation denotes enhancement
T14664 28914-28925 Positive_regulation denotes GP-mediated
T14663 28952-28959 Positive_regulation denotes induced
T14662 28827-28834 Positive_regulation denotes induced
T14661 28967-28977 Gene_expression denotes production
T14660 28835-28842 Binding denotes binding
T14659 28624-28631 Positive_regulation denotes induced
T14658 28598-28609 Regulation denotes modulations
T14657 28632-28639 Binding denotes binding
T14656 28353-28360 Regulation denotes altered
T14655 28523-28536 Positive_regulation denotes up-regulation
T14654 28447-28462 Negative_regulation denotes down-regulation
T14653 28372-28379 Positive_regulation denotes induced
T14652 27629-27650 Positive_regulation denotes neutrophil-attracting
T14651 27612-27621 Positive_regulation denotes induction
T14650 27474-27481 Positive_regulation denotes leading
T14649 27485-27492 Localization denotes release
T14648 27408-27415 Binding denotes binding
T14647 27205-27213 Positive_regulation denotes mediated
T14646 27301-27311 Gene_expression denotes expression
T14645 26925-26932 Gene_expression denotes produce
T14644 26814-26821 Gene_expression denotes produce
T14642 26695-26704 Positive_regulation denotes induction
T14641 26567-26574 Positive_regulation denotes induced
T14640 26455-26463 Negative_regulation denotes decrease
T14639 26355-26364 Positive_regulation denotes activated
T14638 26289-26292 Positive_regulation denotes due
T14637 26265-26272 Binding denotes binding
T14636 26228-26237 Positive_regulation denotes induction
T14635 25834-25841 Positive_regulation denotes induced
T14634 25804-25810 Positive_regulation denotes induce
T14633 25503-25510 Binding denotes binding
T14632 25271-25282 Positive_regulation denotes GP-mediated
T14631 25394-25401 Binding denotes binding
T14630 25335-25349 Positive_regulation denotes transactivated
T14629 25315-25326 Binding denotes cooperation
T14628 25288-25301 Transcription denotes transcription
T14627 25068-25075 Positive_regulation denotes pointed
T14626 25237-25248 Positive_regulation denotes GP-mediated
T14625 25224-25228 Positive_regulation denotes case
T14624 25127-25137 Positive_regulation denotes activation
T14623 25082-25091 Positive_regulation denotes induction
T14622 25254-25267 Transcription denotes transcription
T14621 25191-25203 Binding denotes heterodimers
T14620 25100-25113 Transcription denotes transcription
T14619 24896-24907 Positive_regulation denotes GP-mediated
T14618 24920-24927 Binding denotes binding
T14617 24758-24777 Positive_regulation denotes 3-D-glucan-mediated
T14616 24804-24814 Gene_expression denotes production
T14615 24441-24451 Positive_regulation denotes activation
T14614 24388-24395 Binding denotes binding
T14613 24263-24270 Positive_regulation denotes induced
T14612 24271-24278 Binding denotes binding
T14611 32024-32030 Protein denotes IL-1RA
T14610 31698-31702 Protein denotes NFAT
T14609 31602-31607 Protein denotes IL-1β
T14608 31587-31593 Protein denotes IL-1RA
T14607 31362-31368 Protein denotes TSST-1
T14606 31346-31352 Protein denotes TSST-1
T14605 31064-31070 Protein denotes TSST-1
T14604 31095-31099 Protein denotes IL-2
T14603 31080-31084 Protein denotes IL-1
T14602 30993-30998 Protein denotes IL-1β
T14601 30919-30925 Protein denotes TSST-1
T14600 30891-30897 Protein denotes IL-1RA
T14599 30885-30890 Protein denotes IL-1β
T14598 30851-30855 Protein denotes IL-1
T14597 30805-30810 Protein denotes IL-1β
T14596 30793-30799 Protein denotes IL-1RA
T14595 30702-30708 Protein denotes TSST-1
T14594 30674-30680 Protein denotes IL-1RA
T14593 30668-30673 Protein denotes IL-1β
T14592 30552-30558 Protein denotes IL-1RA
T14591 30537-30543 Protein denotes TSST-1
T14590 30364-30370 Protein denotes TSST-1
T14589 30158-30164 Protein denotes TSST-1
T14588 29948-29954 Protein denotes IL-1RA
T14587 29647-29653 Protein denotes IL-1RA
T14586 29634-29638 Protein denotes TNFα
T14585 29432-29438 Protein denotes IL-1RA
T14584 29349-29353 Protein denotes TNFα
T14583 29305-29311 Protein denotes TSST-1
T14582 29149-29155 Protein denotes TSST-1
T14581 29096-29102 Protein denotes TSST-1
T14580 29068-29074 Protein denotes IL-1RA
T14579 28960-28966 Protein denotes IL-1RA
T14578 28945-28951 Protein denotes TSST-1
T14577 28869-28873 Protein denotes TNFα
T14576 28820-28826 Protein denotes TSST-1
T14575 28774-28778 Protein denotes IFNγ
T14574 28766-28770 Protein denotes IL-6
T14573 28759-28764 Protein denotes IL-1β
T14572 28753-28757 Protein denotes TNFα
T14571 28722-28728 Protein denotes IL-1RA
T14570 28713-28717 Protein denotes IL-8
T14569 28660-28664 Protein denotes NFAT
T14568 28649-28655 Protein denotes NFIL-6
T14567 28617-28623 Protein denotes TSST-1
T14566 28540-28546 Protein denotes IL-1RA
T14565 28476-28480 Protein denotes IL-6
T14564 28466-28471 Protein denotes IL-1β
T14563 28386-28392 Protein denotes IL-1RA
T14562 28380-28385 Protein denotes IL-1β
T14561 28365-28371 Protein denotes TSST-1
T14560 28201-28207 Protein denotes TSST-1
T10876 22780-22789 Negative_regulation denotes decreased
T10875 22771-22774 Positive_regulation denotes led
T10874 22797-22804 Localization denotes release
T10873 21994-22003 Negative_regulation denotes reduction
T10872 21784-21794 Negative_regulation denotes inhibition
T10871 21724-21732 Positive_regulation denotes relevant
T10870 21741-21750 Positive_regulation denotes induction
T10869 21576-21579 Positive_regulation denotes led
T10868 21583-21590 Negative_regulation denotes reduced
T10867 22790-22796 Protein denotes IL-1RA
T10866 22572-22578 Protein denotes IL-1RA
T10865 22460-22466 Protein denotes IL-1RA
T10864 22319-22325 Protein denotes IL-1RA
T10863 22023-22029 Protein denotes IL-1RA
T10862 22007-22013 Protein denotes IL-1RA
T10861 21974-21980 Protein denotes IL-1RA
T10860 21843-21849 Protein denotes NFIL-6
T10859 21826-21830 Protein denotes NFAT
T10858 21754-21760 Protein denotes IL-1RA
T10857 21704-21710 Protein denotes IL-1RA
T10856 21591-21597 Protein denotes IL-1RA
T9986 20642-20651 Positive_regulation denotes dependent
T9985 20621-20629 Negative_regulation denotes decrease
T9984 20652-20659 Localization denotes release
T9983 20490-20496 Positive_regulation denotes higher
T9982 20497-20507 Gene_expression denotes production
T9981 19993-20001 Positive_regulation denotes resulted
T9980 20016-20020 Positive_regulation denotes more
T9979 20005-20015 Positive_regulation denotes generating
T9978 19661-19670 Regulation denotes modulated
T9977 19682-19689 Positive_regulation denotes induced
T9976 20743-20749 Protein denotes TSST-1
T9975 20730-20736 Protein denotes TSST-1
T9974 20706-20712 Protein denotes TSST-1
T9973 20663-20667 Protein denotes IL-2
T9972 20637-20641 Protein denotes IL-1
T9971 20526-20531 Protein denotes IL-1β
T9970 20511-20517 Protein denotes IL-1RA
T9969 20332-20338 Protein denotes TSST-1
T9968 20310-20316 Protein denotes TSST-1
T9967 20272-20278 Protein denotes TSST-1
T9966 20186-20192 Protein denotes IL-1RA
T9965 20180-20185 Protein denotes IL-1β
T9964 20032-20038 Protein denotes IL-1RA
T9963 20021-20026 Protein denotes IL-1β
T9962 19899-19905 Protein denotes IL-1RA
T9961 19893-19898 Protein denotes IL-1β
T9960 19784-19790 Protein denotes IL-1RA
T9959 19774-19779 Protein denotes IL-1β
T9958 19696-19702 Protein denotes IL-1RA
T9957 19690-19695 Protein denotes IL-1β
T9956 19675-19681 Protein denotes TSST-1
T8765 18348-18356 Positive_regulation denotes elevated
T8764 18222-18229 Binding denotes binding
T8763 17850-17859 Positive_regulation denotes increased
T8762 17839-17846 Positive_regulation denotes induced
T8761 17860-17867 Binding denotes binding
T8760 17547-17561 Negative_regulation denotes down-regulated
T8759 17497-17504 Binding denotes binding
T8758 17405-17413 Positive_regulation denotes elevated
T8757 17122-17130 Positive_regulation denotes -induced
T8756 16482-16486 Binding denotes bind
T8755 16289-16296 Positive_regulation denotes induced
T8754 16304-16314 Gene_expression denotes expression
T8753 16232-16239 Binding denotes binding
T8752 16202-16206 Positive_regulation denotes Role
T8751 18336-18342 Protein denotes TSST-1
T8750 18301-18307 Protein denotes TSST-1
T8749 17906-17912 Protein denotes TSST-1
T8748 17832-17838 Protein denotes TSST-1
T8747 17468-17474 Protein denotes TSST-1
T8746 17423-17429 Protein denotes TSST-1
T8745 17291-17297 Protein denotes TSST-1
T8744 17230-17236 Protein denotes TSST-1
T8743 17096-17102 Protein denotes TSST-1
T8742 17000-17006 Protein denotes TSST-1
T8741 16620-16626 Protein denotes IL-1RA
T8740 16503-16509 Protein denotes IL-1RA
T8739 16413-16417 Protein denotes IFNγ
T8738 16405-16409 Protein denotes IL-6
T8737 16399-16403 Protein denotes TNFα
T8736 16297-16303 Protein denotes IL-1RA
T8735 16282-16288 Protein denotes TSST-1
T8734 16249-16255 Protein denotes TSST-1
T8733 16227-16231 Protein denotes NFAT
T8732 16216-16222 Protein denotes NFIL-6
T6387 13488-13499 Positive_regulation denotes LPS-induced
T6386 13505-13515 Gene_expression denotes production
T6385 13405-13412 Positive_regulation denotes induced
T6384 11919-11928 Negative_regulation denotes reduction
T6383 11796-11809 Positive_regulation denotes up-regulation
T6382 11819-11829 Gene_expression denotes production
T6381 11710-11720 Gene_expression denotes production
T6380 11055-11059 Positive_regulation denotes lead
T6379 11063-11073 Gene_expression denotes production
T6378 16160-16166 Protein denotes TSST-1
T6377 16147-16153 Protein denotes TSST-1
T6376 16103-16109 Protein denotes TSST-1
T6375 16001-16007 Protein denotes TGFβ 1
T6374 15991-15996 Protein denotes IL-10
T6373 15985-15989 Protein denotes IL-4
T6372 15978-15983 Protein denotes IL-12
T6371 15972-15976 Protein denotes IL-2
T6370 15948-15953 Protein denotes TGFβ1
T6369 15941-15946 Protein denotes IL-10
T6368 15935-15939 Protein denotes IL-4
T6367 15928-15933 Protein denotes IL-12
T6366 15922-15926 Protein denotes IL-2
T6365 15884-15890 Protein denotes TSST-1
T6364 15871-15877 Protein denotes TSST-1
T6363 15829-15835 Protein denotes TSST-1
T6362 15703-15707 Protein denotes IFNγ
T6361 15598-15602 Protein denotes IFNγ
T6360 15590-15594 Protein denotes IFNγ
T6359 15449-15453 Protein denotes TNFα
T6358 15392-15398 Protein denotes TSST-1
T6357 15379-15385 Protein denotes TSST-1
T6356 15291-15295 Protein denotes TNFα
T6355 15142-15146 Protein denotes TNFα
T6354 15121-15125 Protein denotes TNFα
T6353 15044-15050 Protein denotes IL-1RA
T6352 15035-15039 Protein denotes IL-8
T6351 14924-14930 Protein denotes IL-1RA
T6350 14915-14919 Protein denotes IL-8
T6349 14814-14820 Protein denotes IL-1RA
T6348 14805-14809 Protein denotes IL-8
T6347 14725-14731 Protein denotes IL-1RA
T6346 14700-14706 Protein denotes TSST-1
T6345 14620-14626 Protein denotes TSST-1
T6344 14539-14545 Protein denotes TSST-1
T6341 14400-14406 Protein denotes IL-1RA
T6340 14164-14170 Protein denotes IL-1RA
T6339 14158-14162 Protein denotes IL-8
T6338 14143-14149 Protein denotes IL-1RA
T6337 14096-14102 Protein denotes TSST-1
T6336 14083-14089 Protein denotes TSST-1
T6335 14059-14065 Protein denotes TSST-1
T6334 14028-14032 Protein denotes IL-8
T6333 13936-13940 Protein denotes IL-8
T6332 13775-13779 Protein denotes IL-8
T6331 13731-13735 Protein denotes IL-8
T6330 13626-13632 Protein denotes TSST-1
T6329 13613-13619 Protein denotes TSST-1
T6328 13589-13595 Protein denotes TSST-1
T6327 13564-13568 Protein denotes IL-6
T6326 13500-13504 Protein denotes IL-6
T6325 13436-13440 Protein denotes IL-6
T6324 13397-13401 Protein denotes IL-6
T6323 12146-12151 Protein denotes IL-1β
T6322 12121-12127 Protein denotes TSST-1
T6321 12039-12045 Protein denotes TSST-1
T6320 12001-12007 Protein denotes TSST-1
T6319 11932-11937 Protein denotes IL-1β
T6318 11889-11895 Protein denotes TSST-1
T6317 11813-11818 Protein denotes IL-1β
T6316 11704-11709 Protein denotes IL-1β
T6315 11685-11690 Protein denotes IL-1β
T6314 11671-11677 Protein denotes TSST-1
T6313 11089-11093 Protein denotes IL-6
T6312 11083-11087 Protein denotes IL-8
T6311 11077-11081 Protein denotes TNFα
T6310 10981-10985 Protein denotes IFNγ
T6309 10972-10976 Protein denotes IL-6
T6308 10966-10970 Protein denotes IL-8
T6307 10960-10964 Protein denotes TNFα
T6306 11095-11099 Protein denotes IFNγ
T6305 10891-10897 Protein denotes TSST-1
T6304 10861-10867 Protein denotes TSST-1
T6421 16016-16023 Positive_regulation denotes induced
T6420 15958-15968 Gene_expression denotes production
T6419 15691-15699 Positive_regulation denotes increase
T6418 15814-15823 Positive_regulation denotes following
T6417 15798-15813 Negative_regulation denotes down-regulation
T6416 15708-15718 Gene_expression denotes production
T6415 15629-15638 Positive_regulation denotes following
T6414 15603-15613 Gene_expression denotes production
T6413 15439-15445 Regulation denotes effect
T6412 15454-15463 Localization denotes secretion
T6411 15280-15286 Regulation denotes change
T6410 15296-15306 Gene_expression denotes production
T6409 15147-15157 Gene_expression denotes production
T6408 15009-15016 Positive_regulation denotes induced
T6407 14794-14804 Positive_regulation denotes GP-induced
T6406 14821-14832 Gene_expression denotes productions
T6405 14473-14481 Positive_regulation denotes increase
T6404 14428-14437 Positive_regulation denotes following
T6403 14492-14502 Gene_expression denotes production
T6402 14368-14373 Regulation denotes alter
T6401 14407-14417 Gene_expression denotes production
T6400 14238-14247 Positive_regulation denotes following
T6399 14203-14211 Gene_expression denotes produced
T6398 14014-14024 Regulation denotes alteration
T6397 14044-14053 Positive_regulation denotes following
T6396 14033-14043 Gene_expression denotes production
T6395 13894-13902 Positive_regulation denotes resulted
T6394 13924-13932 Positive_regulation denotes increase
T6393 13941-13951 Gene_expression denotes production
T6392 13753-13760 Positive_regulation denotes induced
T6391 13780-13790 Gene_expression denotes production
T6390 13554-13563 Negative_regulation denotes decreased
T6389 13569-13579 Gene_expression denotes production
T6388 13470-13480 Regulation denotes alteration
T605 17-26 Positive_regulation denotes modulates
T597 1747-1752 Protein denotes IL-1β
T598 1753-1759 Protein denotes IL-1RA
T599 1851-1857 Protein denotes TSST-1
T600 1867-1871 Protein denotes IL-1
T601 1896-1900 Protein denotes IL-2
T602 2102-2108 Protein denotes IL-1RA
T603 2199-2205 Protein denotes IL-1RA
T604 31-38 Binding denotes binding
T606 631-641 Positive_regulation denotes activation
T607 750-760 Gene_expression denotes production
T608 817-824 Positive_regulation denotes induced
T609 882-889 Positive_regulation denotes induced
T610 961-968 Binding denotes binding
T611 1062-1072 Gene_expression denotes production
T612 1022-1030 Positive_regulation denotes increase
T613 1212-1219 Binding denotes binding
T614 1192-1199 Positive_regulation denotes induced
T615 1496-1503 Binding denotes binding
T616 1555-1563 Positive_regulation denotes increase
T617 1451-1459 Positive_regulation denotes elevated
T618 1484-1491 Positive_regulation denotes induced
T619 1656-1665 Negative_regulation denotes reduction
T620 1739-1746 Positive_regulation denotes induced
T621 1720-1727 Negative_regulation denotes shifted
T622 1882-1892 Gene_expression denotes production
T623 1858-1865 Positive_regulation denotes induced
T624 1837-1846 Negative_regulation denotes decreased
T625 2181-2191 Regulation denotes regulation
T626 2225-2234 Regulation denotes modulated
T2030 2732-2740 Protein denotes Dectin-1
T2031 3007-3015 Protein denotes Dectin-1
T2032 3042-3046 Protein denotes TNFα
T2033 3055-3075 Protein denotes Toll-like receptor 2
T2034 3100-3105 Protein denotes MyD88
T2035 3202-3208 Protein denotes NFIL-6
T2036 3461-3465 Protein denotes IL-1
T2037 3467-3471 Protein denotes IL-6
T2038 3473-3477 Protein denotes TNFα
T2039 3549-3555 Protein denotes IL-1RA
T2040 3565-3569 Protein denotes IL-1
T2041 3771-3775 Protein denotes IL-8
T2042 4917-4923 Protein denotes TSST-1
T2043 5048-5052 Protein denotes TNFα
T2044 5054-5059 Protein denotes IL-1β
T2045 5061-5065 Protein denotes IL-6
T2048 5108-5112 Protein denotes IFNγ
T2049 5114-5118 Protein denotes IL-2
T2050 5120-5124 Protein denotes IL-4
T2051 5126-5131 Protein denotes IL-10
T2052 5133-5138 Protein denotes IL-12
T2053 5143-5148 Protein denotes TGFβ1
T2054 5192-5196 Protein denotes TNFα
T2055 5266-5270 Protein denotes IL-8
T2056 5308-5312 Protein denotes IFNγ
T2057 5371-5375 Protein denotes IL-6
T2058 5446-5452 Protein denotes IL-1RA
T2059 5508-5514 Protein denotes IL-1RA
T2060 5627-5633 Protein denotes IL-1RA
T2061 5822-5828 Protein denotes IL-1RA
T2062 2985-2992 Binding denotes binding
T2063 3028-3038 Gene_expression denotes production
T2064 3016-3024 Positive_regulation denotes resulted
T2065 3184-3192 Positive_regulation denotes activate
T2066 3420-3429 Localization denotes secretion
T2067 3513-3523 Gene_expression denotes production
T2068 3631-3638 Positive_regulation denotes induced
T2069 3763-3770 Gene_expression denotes produce
T2070 5468-5475 Binding denotes binding
T3760 5877-5883 Protein denotes NFIL-6
T3761 5888-5892 Protein denotes NFAT
T3762 5916-5920 Protein denotes TNFα
T3763 5922-5926 Protein denotes IL-6
T3764 5931-5935 Protein denotes IFNγ
T3765 5996-6002 Protein denotes TSST-1
T3766 6026-6032 Protein denotes TSST-1
T3767 6223-6227 Protein denotes IL-8
T3768 6263-6267 Protein denotes IL-6
T3769 6098-6104 Protein denotes NFIL-6
T3770 6187-6191 Protein denotes TNFα
T3771 6397-6403 Protein denotes TSST-1
T3772 6475-6479 Protein denotes IL-8
T3773 6544-6547 Protein denotes p65
T3774 6574-6577 Protein denotes p50
T3775 6689-6692 Protein denotes p65
T3776 6718-6721 Protein denotes p50
T3777 6731-6734 Protein denotes p52
T3778 6863-6867 Protein denotes TNFα
T3779 6934-6940 Protein denotes TSST-1
T3780 6979-6985 Protein denotes TSST-1
T3781 7063-7069 Protein denotes TSST-1
T3782 7100-7106 Protein denotes TSST-1
T3783 7130-7136 Protein denotes TSST-1
T3784 7235-7239 Protein denotes NFAT
T3785 7261-7265 Protein denotes IFNγ
T3786 7308-7312 Protein denotes NFAT
T3787 7359-7365 Protein denotes NFATc2
T3788 7392-7398 Protein denotes NFATc1
T3789 5849-5856 Binding denotes Binding
T3790 5857-5867 Positive_regulation denotes activities
T3791 6068-6075 Binding denotes binding
T3792 6036-6043 Positive_regulation denotes induced
T3793 6528-6535 Binding denotes binding
T3794 6505-6515 Positive_regulation denotes GP-induced
T3795 6673-6680 Binding denotes binding
T3796 6739-6747 Negative_regulation denotes negative
T3797 6836-6843 Binding denotes binding
T3798 7201-7208 Binding denotes binding
T3799 7348-7355 Binding denotes binding
T3800 7322-7334 Positive_regulation denotes demonstrated
T3801 7337-7347 Positive_regulation denotes GP-induced
T570 69-73 Protein denotes IL-6
T571 119-124 Protein denotes IL-1β
T572 125-149 Protein denotes IL-1 receptor antagonist
T573 572-600 Protein denotes toxic shock syndrome toxin 1
T574 602-608 Protein denotes TSST-1
T575 771-775 Protein denotes IL-6
T576 777-800 Protein denotes tumor necrosis factor α
T577 804-816 Protein denotes interferon γ
T578 668-687 Protein denotes NFinterleukin(IL)-6
T579 692-696 Protein denotes NFAT
T580 715-721 Protein denotes TSST-1
T581 764-769 Protein denotes IL-1β
T582 914-918 Protein denotes IL-8
T583 1004-1008 Protein denotes IL-8
T584 1034-1057 Protein denotes IL-1receptor antagonist
T585 1058-1060 Protein denotes RA
T586 1162-1166 Protein denotes IL-8
T587 1274-1280 Protein denotes IL-1RA
T588 1385-1391 Protein denotes TSST-1
T589 1477-1483 Protein denotes TSST-1
T590 1513-1519 Protein denotes NFIL-6
T591 1524-1528 Protein denotes NFAT
T592 1567-1573 Protein denotes IL-1RA
T593 1615-1621 Protein denotes TSST-1
T594 1669-1674 Protein denotes IL-1β
T595 1679-1683 Protein denotes IL-6
T596 1732-1738 Protein denotes TSST-1
T2046 5067-5071 Protein denotes IL-8
T2047 5076-5082 Protein denotes IL-1RA
T6342 14443-14449 Protein denotes TSST-1
T6343 14485-14491 Protein denotes IL-1RA
T14542 26473-26477 Protein denotes NFAT
T14541 26421-26427 Protein denotes IL-1RA
T14643 26681-26690 Positive_regulation denotes necessary
T21181 40435-40441 Protein denotes TSST-1
T21180 40422-40428 Protein denotes TSST-1
T21183 40720-40726 Protein denotes TSST-1
T21182 40707-40713 Protein denotes TSST-1
T26237 27870-27876 Protein denotes IL-1RA
T25845 23549-23556 Negative_regulation denotes reduced
T25844 23596-23605 Positive_regulation denotes following
T25843 23561-23571 Gene_expression denotes production
T25842 23499-23509 Negative_regulation denotes Inhibition
T25841 23364-23373 Negative_regulation denotes decreased
T25840 23352-23360 Positive_regulation denotes resulted
T25839 23316-23326 Negative_regulation denotes Inhibition
T25838 22867-22874 Binding denotes binding
T25837 22830-22840 Positive_regulation denotes GP-induced
T25836 22816-22826 Negative_regulation denotes Inhibition
T25835 23528-23534 Protein denotes NFIL-6
T25834 23519-23523 Protein denotes NFAT
T25833 23575-23581 Protein denotes IL-1RA
T25832 23429-23434 Protein denotes GAPDH
T25831 23374-23380 Protein denotes IL-1RA
T25830 23345-23351 Protein denotes NFIL-6
T25829 23336-23340 Protein denotes NFAT
T25828 22882-22888 Protein denotes IL-1RA
T25827 22856-22862 Protein denotes NFIL-6
T25826 22847-22851 Protein denotes NFAT
T25138 21443-21449 Positive_regulation denotes higher
T25137 21450-21460 Gene_expression denotes production
T25136 21068-21076 Positive_regulation denotes resulted
T25135 21080-21090 Positive_regulation denotes generating
T25134 20840-20849 Positive_regulation denotes following
T25133 20811-20820 Negative_regulation denotes Decreased
T25132 21479-21484 Protein denotes IL-1β
T25131 21464-21470 Protein denotes IL-1RA
T25130 21300-21306 Protein denotes TSST-1
T25129 21279-21285 Protein denotes TSST-1
T25128 21266-21272 Protein denotes TSST-1
T25127 21226-21232 Protein denotes IL-1RA
T25126 21220-21225 Protein denotes IL-1β
T25125 21107-21113 Protein denotes IL-1RA
T25124 21096-21101 Protein denotes IL-1β
T25123 21027-21033 Protein denotes TSST-1
T25122 21014-21020 Protein denotes TSST-1
T25121 20977-20983 Protein denotes TSST-1
T25120 20919-20925 Protein denotes IL-1RA
T25119 20913-20918 Protein denotes IL-1β
R146 T610 T609 themeOf binding,induced
R148 T611 T612 themeOf production,increase
R307 T585 T611 themeOf RA,production
R314 T595 T619 themeOf IL-6,reduction
R9547 T14505 T14612 themeOf NFIL-6,binding
R9549 T14506 T14612 themeOf NFAT,binding
R9550 T14507 T14614 themeOf NFAT,binding
R9551 T14508 T14615 themeOf NFAT,activation
R9553 T14511 T14616 themeOf IL-8,production
R9558 T14514 T14618 themeOf IL-8,binding
R9560 T14515 T14618 themeOf p65,binding
R9562 T14516 T14620 themeOf IL-8,transcription
R9563 T14517 T14621 themeOf p65,heterodimers
R9566 T14519 T14621 themeOf p65,heterodimers
R9568 T14521 T14622 themeOf IL-8,transcription
R9569 T14522 T14628 themeOf IL-8,transcription
R9571 T14523 T14629 themeOf p65,cooperation
R9572 T14523 T14630 themeOf p65,transactivated
R9573 T14523 T14631 themeOf p65,binding
R9575 T14525 T14631 themeOf NFATc2,binding
R9578 T14528 T14633 themeOf p65,binding
R9582 T14532 T14634 themeOf IL-1β,induce
R9583 T14533 T14635 themeOf IL-1RA,induced
R9585 T14535 T14636 themeOf NFATP2,induction
R9586 T14535 T14637 themeOf NFATP2,binding
R9588 T14537 T14637 themeOf NFIL-6,binding
R9589 T14538 T14639 themeOf NFAT,activated
R9597 T14542 T14640 themeOf NFAT,decrease
R9600 T14546 T14642 themeOf IL-1RA,induction
R9601 T14547 T14644 themeOf IL-1RA,produce
R9603 T14548 T14645 themeOf IL-8,produce
R9606 T14552 T14647 causeOf Toll-like receptor 4,mediated
R9608 T14553 T14646 themeOf TNFα,expression
R9609 T14554 T14648 themeOf TSST-1,binding
R9610 T14555 T14649 themeOf IFNγ,release
R9613 T14558 T14651 themeOf IL-8,induction
R9614 T14558 T14652 themeOf IL-8,neutrophil-attracting
R9618 T14561 T14653 causeOf TSST-1,induced
R9619 T14562 T14653 themeOf IL-1β,induced
R9620 T14564 T14654 themeOf IL-1β,down-regulation
R9623 T14566 T14655 themeOf IL-1RA,up-regulation
R9624 T14567 T14659 causeOf TSST-1,induced
R9626 T14568 T14657 themeOf NFIL-6,binding
R9627 T14570 T14657 themeOf IL-8,binding
R9629 T14576 T14662 causeOf TSST-1,induced
R9630 T14577 T14660 themeOf TNFα,binding
R9631 T14578 T14663 causeOf TSST-1,induced
R9633 T14579 T14661 themeOf IL-1RA,production
R9634 T14581 T14666 themeOf TSST-1,binding
R9638 T14584 T14669 themeOf TNFα,binding
R9660 T14612 T14613 themeOf binding,induced
R9663 T14616 T14617 themeOf production,3-D-glucan-mediated
R9665 T14618 T14619 themeOf binding,GP-mediated
R9667 T14620 T14623 themeOf transcription,induction
R9668 T14621 T14624 themeOf heterodimers,activation
R9669 T14622 T14625 themeOf transcription,case
R9670 T14622 T14626 themeOf transcription,GP-mediated
R9672 T14623 T14627 themeOf induction,pointed
R9675 T14628 T14632 themeOf transcription,GP-mediated
R9680 T14636 T14638 themeOf induction,due
R9683 T14640 T14641 themeOf decrease,induced
R9687 T14641 T14640 themeOf induced,decrease
R9688 T14642 T14643 themeOf induction,necessary
R9691 T14646 T14647 themeOf expression,mediated
R9692 T14649 T14650 themeOf release,leading
R9693 T14649 T14650 themeOf release,leading
R9695 T14652 T14651 themeOf neutrophil-attracting,induction
R9696 T14653 T14656 themeOf induced,altered
R9697 T14653 T14656 themeOf induced,altered
R9698 T14654 T14656 causeOf down-regulation,altered
R9699 T14654 T14656 causeOf down-regulation,altered
R9700 T14657 T14658 themeOf binding,modulations
R9701 T14657 T14659 themeOf binding,induced
R9702 T14660 T14662 themeOf binding,induced
R9704 T14661 T14663 themeOf production,induced
R9705 T14663 T14664 themeOf induced,GP-mediated
R9706 T14663 T14665 themeOf induced,enhancement
R9708 T14665 T14664 themeOf enhancement,GP-mediated
R9709 T14666 T14667 themeOf binding,increased
R9710 T14666 T14668 themeOf binding,LPS-induced
R9718 T14682 T14683 themeOf production,controls
R9719 T14684 T14685 themeOf activation,involved
R11632 T17284 T17287 themeOf IL-1RA,binding
R11633 T17284 T17288 themeOf IL-1RA,regulated
R11634 T17285 T17289 themeOf IL-1β,dysregulated
R12663 T18519 T18520 themeOf NFAT,binding
R12664 T18520 T18521 themeOf binding,crucial
R13019 T18977 T18978 themeOf Oct-1,excess
R13020 T18977 T18979 themeOf Oct-1,binding
R14140 T20592 T20600 themeOf IL-1RA,binding
R14141 T20593 T20601 themeOf NFIL-6,binding
R14142 T20593 T20601 themeOf NFIL-6,binding
R14143 T20594 T20601 themeOf NFATP2,binding
R14144 T20594 T20601 themeOf NFATP2,binding
R14145 T20595 T20601 themeOf 3,binding
R14146 T20596 T20601 themeOf IL-1RA,binding
R14147 T20596 T20601 themeOf IL-1RA,binding
R14148 T20596 T20601 themeOf IL-1RA,binding
R15027 T21879 T21900 themeOf NFAT,binding
R15028 T21879 T21900 themeOf NFAT,binding
R15029 T21880 T21900 themeOf NFIL-6,binding
R15030 T21884 T21902 themeOf IFNγ,corresponding
R15031 T21885 T21902 themeOf TNFα,corresponding
R15032 T21886 T21902 themeOf IL-6,corresponding
R15033 T21894 T21903 themeOf TSST-1,binding
R15034 T21900 T21901 themeOf binding,led
R15035 T21900 T21901 themeOf binding,led
R15036 T21903 T21904 themeOf binding,Decreased
R15458 T22608 T22623 themeOf p65,binding
R15459 T22608 T22623 themeOf p65,binding
R15460 T22610 T22623 themeOf NFATc2,binding
R15461 T22611 T22623 themeOf c1,binding
R15462 T22613 T22624 themeOf NFATc1,positive
R15463 T22615 T22625 themeOf p65,positive
R15464 T22616 T22625 themeOf p50,positive
R15465 T22617 T22625 themeOf NFAT c2,positive
R15466 T22618 T22625 themeOf c1,positive
R15467 T22621 T22624 themeOf p50,positive
R15468 T22622 T22624 themeOf p65,positive
R15929 T23394 T23413 themeOf IL-1β,production
R15930 T23397 T23414 themeOf IL-1β,production
R1086 T2058 T2070 themeOf IL-1RA,binding
R1087 T2031 T2062 themeOf Dectin-1,binding
R1088 T2032 T2063 themeOf TNFα,production
R1089 T2033 T2063 themeOf Toll-like receptor 2,production
R1090 T2034 T2063 themeOf MyD88,production
R1091 T2035 T2065 themeOf NFIL-6,activate
R1092 T2036 T2066 themeOf IL-1,secretion
R1093 T2037 T2066 themeOf IL-6,secretion
R1094 T2038 T2066 themeOf TNFα,secretion
R1095 T2059 T2070 themeOf IL-1RA,binding
R1096 T2039 T2067 themeOf IL-1RA,production
R1097 T2040 T2067 themeOf IL-1,production
R1098 T2041 T2069 themeOf IL-8,produce
R1099 T2062 T2064 causeOf binding,resulted
R1100 T2062 T2064 causeOf binding,resulted
R1101 T2062 T2064 causeOf binding,resulted
R1102 T2063 T2064 themeOf production,resulted
R1103 T2063 T2064 themeOf production,resulted
R1104 T2063 T2064 themeOf production,resulted
R1105 T2067 T2068 themeOf production,induced
R1106 T2067 T2068 themeOf production,induced
R2317 T3760 T3789 themeOf NFIL-6,Binding
R2318 T3760 T3790 themeOf NFIL-6,activities
R2319 T3761 T3789 themeOf NFAT,Binding
R2320 T3761 T3790 themeOf NFAT,activities
R2321 T3762 T3789 themeOf TNFα,Binding
R2322 T3762 T3789 themeOf TNFα,Binding
R2323 T3763 T3790 themeOf IL-6,activities
R2324 T3767 T3791 themeOf IL-8,binding
R2325 T3768 T3791 themeOf IL-6,binding
R2326 T3769 T3791 themeOf NFIL-6,binding
R2327 T3769 T3791 themeOf NFIL-6,binding
R2328 T3773 T3793 themeOf p65,binding
R2329 T3774 T3793 themeOf p50,binding
R2330 T3775 T3795 themeOf p65,binding
R2331 T3776 T3795 themeOf p50,binding
R2332 T3777 T3796 themeOf p52,negative
R2333 T3778 T3797 themeOf TNFα,binding
R2334 T3784 T3798 themeOf NFAT,binding
R2335 T3785 T3798 themeOf IFNγ,binding
R2336 T3787 T3799 themeOf NFATc2,binding
R2337 T3788 T3799 themeOf NFATc1,binding
R2338 T3789 T3790 themeOf Binding,activities
R2339 T3789 T3790 themeOf Binding,activities
R2340 T3791 T3792 themeOf binding,induced
R2341 T3791 T3792 themeOf binding,induced
R2342 T3793 T3794 themeOf binding,GP-induced
R2343 T3799 T3800 themeOf binding,demonstrated
R2344 T3799 T3801 themeOf binding,GP-induced
R3920 T6343 T6403 themeOf IL-1RA,production
R3921 T6306 T6379 themeOf IFNγ,production
R3922 T6348 T6406 themeOf IL-8,productions
R3923 T6311 T6379 themeOf TNFα,production
R3924 T6349 T6406 themeOf IL-1RA,productions
R3925 T6312 T6379 themeOf IL-8,production
R3926 T6313 T6379 themeOf IL-6,production
R3927 T6352 T6408 themeOf IL-8,induced
R3928 T6316 T6381 themeOf IL-1β,production
R3929 T6317 T6382 themeOf IL-1β,production
R3930 T6319 T6384 themeOf IL-1β,reduction
R3931 T6353 T6408 themeOf IL-1RA,induced
R3932 T6325 T6385 themeOf IL-6,induced
R3933 T6326 T6386 themeOf IL-6,production
R3934 T6355 T6409 themeOf TNFα,production
R3935 T6327 T6389 themeOf IL-6,production
R3936 T6328 T6389 themeOf TSST-1,production
R3937 T6356 T6410 themeOf TNFα,production
R3938 T6332 T6391 themeOf IL-8,production
R3939 T6333 T6393 themeOf IL-8,production
R3940 T6359 T6412 themeOf TNFα,secretion
R3941 T6334 T6396 themeOf IL-8,production
R3942 T6335 T6396 themeOf TSST-1,production
R3943 T6361 T6414 themeOf IFNγ,production
R3944 T6339 T6399 themeOf IL-8,produced
R3945 T6340 T6399 themeOf IL-1RA,produced
R3946 T6341 T6401 themeOf IL-1RA,production
R3947 T6362 T6416 themeOf IFNγ,production
R3948 T6363 T6417 themeOf TSST-1,down-regulation
R3949 T6371 T6420 themeOf IL-2,production
R3950 T6372 T6420 themeOf IL-12,production
R3951 T6373 T6420 themeOf IL-4,production
R3952 T6374 T6420 themeOf IL-10,production
R3955 T6375 T6420 themeOf TGFβ 1,production
R3957 T6379 T6380 themeOf production,lead
R3959 T6379 T6380 themeOf production,lead
R3960 T6379 T6380 themeOf production,lead
R3961 T6379 T6380 themeOf production,lead
R3962 T6382 T6383 themeOf production,up-regulation
R3963 T6386 T6387 themeOf production,LPS-induced
R3966 T6387 T6388 themeOf LPS-induced,alteration
R3970 T6389 T6390 themeOf production,decreased
R3971 T6389 T6390 themeOf production,decreased
R3973 T6391 T6392 themeOf production,induced
R3976 T6393 T6394 themeOf production,increase
R3980 T6394 T6395 themeOf increase,resulted
R3982 T6396 T6397 themeOf production,following
R3987 T6396 T6398 themeOf production,alteration
R3988 T6396 T6397 themeOf production,following
R3990 T6396 T6398 themeOf production,alteration
R3991 T6399 T6400 themeOf produced,following
R3993 T6399 T6400 themeOf produced,following
R3995 T6401 T6402 themeOf production,alter
R3997 T6403 T6404 themeOf production,following
R4001 T6403 T6405 themeOf production,increase
R4002 T6406 T6407 themeOf productions,GP-induced
R4003 T6406 T6407 themeOf productions,GP-induced
R4004 T6410 T6411 themeOf production,change
R4007 T6412 T6413 themeOf secretion,effect
R4009 T6414 T6415 themeOf production,following
R4012 T6416 T6418 themeOf production,following
R4015 T6416 T6419 themeOf production,increase
R4016 T6420 T6421 themeOf production,induced
R4021 T6420 T6421 themeOf production,induced
R4023 T6420 T6421 themeOf production,induced
R4026 T6420 T6421 themeOf production,induced
R4028 T6420 T6421 themeOf production,induced
R5679 T8732 T8752 themeOf NFIL-6,Role
R5680 T8733 T8753 themeOf NFAT,binding
R5681 T8735 T8755 causeOf TSST-1,induced
R5682 T8736 T8754 themeOf IL-1RA,expression
R5683 T8740 T8756 themeOf IL-1RA,bind
R5684 T8743 T8757 themeOf TSST-1,-induced
R5685 T8746 T8758 themeOf TSST-1,elevated
R5686 T8747 T8759 themeOf TSST-1,binding
R5687 T8747 T8760 themeOf TSST-1,down-regulated
R5688 T8748 T8762 causeOf TSST-1,induced
R5689 T8749 T8761 themeOf TSST-1,binding
R5690 T8750 T8764 themeOf TSST-1,binding
R5691 T8751 T8764 themeOf TSST-1,binding
R5692 T8753 T8752 themeOf binding,Role
R5693 T8754 T8755 themeOf expression,induced
R5694 T8759 T8760 themeOf binding,down-regulated
R5695 T8761 T8762 themeOf binding,induced
R5696 T8761 T8763 themeOf binding,increased
R5697 T8764 T8765 themeOf binding,elevated
R6538 T9956 T9977 causeOf TSST-1,induced
R6539 T9957 T9977 themeOf IL-1β,induced
R6540 T9963 T9979 themeOf IL-1β,generating
R6541 T9963 T9980 themeOf IL-1β,more
R6542 T9970 T9982 themeOf IL-1RA,production
R6543 T9972 T9986 causeOf IL-1,dependent
R6544 T9973 T9984 themeOf IL-2,release
R6545 T9977 T9978 themeOf induced,modulated
R6546 T9979 T9981 themeOf generating,resulted
R6547 T9980 T9979 themeOf more,generating
R6548 T9982 T9983 themeOf production,higher
R6549 T9984 T9985 themeOf release,decrease
R6550 T9984 T9986 themeOf release,dependent
R7131 T10856 T10868 themeOf IL-1RA,reduced
R7132 T10858 T10870 themeOf IL-1RA,induction
R7133 T10859 T10872 themeOf NFAT,inhibition
R7134 T10862 T10873 themeOf IL-1RA,reduction
R7135 T10863 T10873 themeOf IL-1RA,reduction
R7136 T10867 T10874 themeOf IL-1RA,release
R7137 T10868 T10869 themeOf reduced,led
R7138 T10870 T10871 themeOf induction,relevant
R7139 T10874 T10875 themeOf release,led
R7140 T10874 T10876 themeOf release,decreased
R137 T597 T620 themeOf IL-1β,induced
R138 T599 T623 causeOf TSST-1,induced
R139 T601 T622 themeOf IL-2,production
R140 T603 T625 themeOf IL-1RA,regulation
R141 T604 T605 themeOf binding,modulates
R142 T607 T608 themeOf production,induced
R143 T607 T608 themeOf production,induced
R144 T607 T608 themeOf production,induced
R145 T607 T608 themeOf production,induced
R147 T611 T612 themeOf production,increase
R149 T613 T614 themeOf binding,induced
R150 T615 T617 themeOf binding,elevated
R151 T615 T618 themeOf binding,induced
R152 T620 T621 themeOf induced,shifted
R153 T622 T623 themeOf production,induced
R154 T623 T624 themeOf induced,decreased
R155 T625 T626 themeOf regulation,modulated
R297 T570 T604 themeOf IL-6,binding
R298 T575 T607 themeOf IL-6,production
R299 T576 T607 themeOf tumor necrosis factor α,production
R300 T577 T607 themeOf interferon γ,production
R301 T579 T606 themeOf NFAT,activation
R302 T581 T607 themeOf IL-1β,production
R303 T582 T609 themeOf IL-8,induced
R304 T582 T610 themeOf IL-8,binding
R305 T583 T610 themeOf IL-8,binding
R306 T584 T611 themeOf IL-1receptor antagonist,production
R308 T587 T613 themeOf IL-1RA,binding
R309 T589 T618 causeOf TSST-1,induced
R310 T590 T615 themeOf NFIL-6,binding
R311 T591 T615 themeOf NFAT,binding
R312 T592 T616 themeOf IL-1RA,increase
R313 T594 T619 themeOf IL-1β,reduction
R315 T596 T620 causeOf TSST-1,induced
R9637 T14583 T14671 causeOf TSST-1,induced
R9639 T14585 T14670 themeOf IL-1RA,up-regulation
R9640 T14586 T14672 themeOf TNFα,binding
R9642 T14587 T14672 themeOf IL-1RA,binding
R9644 T14591 T14674 causeOf TSST-1,induced
R9646 T14592 T14673 themeOf IL-1RA,production
R9647 T14593 T14676 themeOf IL-1β,decrease
R9649 T14596 T14677 themeOf IL-1RA,excess
R9651 T14598 T14678 themeOf IL-1,effects
R9654 T14604 T14679 themeOf IL-2,production
R9655 T14605 T14680 causeOf TSST-1,induced
R9711 T14669 T14671 themeOf binding,induced
R9712 T14673 T14674 themeOf production,induced
R9713 T14674 T14675 themeOf induced,up-regulation
R9715 T14679 T14680 themeOf production,induced
R9716 T14680 T14681 themeOf induced,reduced
R9555 T14512 T14616 themeOf IL-1RA,production
R9598 T14543 T14640 themeOf NFIL-6,decrease
R9604 T14549 T14645 themeOf IL-1RA,produce
R9612 T14556 T14649 themeOf TNFα,release
R9615 T14559 T14651 themeOf IL-1RA,induction
R9622 T14565 T14654 themeOf IL-6,down-regulation
R9648 T14595 T14676 themeOf TSST-1,decrease
R9650 T14597 T14677 themeOf IL-1β,excess
R9657 T14609 T14682 themeOf IL-1β,production
R9658 T14610 T14684 themeOf NFAT,activation
R9659 T14611 T14686 themeOf IL-1RA,activated
R9664 T14616 T14617 themeOf production,3-D-glucan-mediated
R9673 T14624 T14627 themeOf activation,pointed
R9677 T14631 T14630 themeOf binding,transactivated
R9681 T14637 T14636 themeOf binding,induction
R9684 T14640 T14641 themeOf decrease,induced
R9686 T14641 T14640 themeOf induced,decrease
R15931 T23398 T23414 themeOf TSST-1,production
R15932 T23405 T23417 themeOf IL-1RA,production
R15933 T23409 T23418 themeOf IL-1RA,production
R15934 T23414 T23415 themeOf production,following
R15935 T23414 T23416 themeOf production,reduction
R15936 T23414 T23415 themeOf production,following
R15937 T23414 T23416 themeOf production,reduction
R16348 T24009 T24014 themeOf TSST-1,binding
R16349 T24009 T24015 causeOf TSST-1,induced
R16350 T24010 T24014 themeOf IL-1RA,binding
R16351 T24014 T24015 themeOf binding,induced
R16657 T24464 T24476 causeOf TSST-1,induced
R16658 T24465 T24475 themeOf IL-1RA,binding
R16659 T24467 T24477 themeOf TSST-1,Binding
R16660 T24470 T24479 themeOf NFAT,binding
R16662 T24475 T24476 themeOf binding,induced
R16663 T24477 T24478 themeOf Binding,up-regulated
R16661 T24471 T24479 themeOf IL-1RA,binding
R16664 T24479 T24480 themeOf binding,elevated
R17047 T25115 T25133 themeOf IL-1β,Decreased
R17048 T25116 T25133 themeOf IL-1RA,Decreased
R17049 T25117 T25134 themeOf TSST-1,following
R17050 T25124 T25135 themeOf IL-1β,generating
R17051 T25131 T25137 themeOf IL-1RA,production
R17052 T25135 T25136 themeOf generating,resulted
R17053 T25137 T25138 themeOf production,higher
R17547 T25826 T25836 themeOf NFAT,Inhibition
R17548 T25826 T25837 themeOf NFAT,GP-induced
R17549 T25826 T25838 themeOf NFAT,binding
R17550 T25828 T25838 themeOf IL-1RA,binding
R17551 T25829 T25840 themeOf NFAT,resulted
R17552 T25830 T25839 themeOf NFIL-6,Inhibition
R17553 T25830 T25840 themeOf NFIL-6,resulted
R17554 T25831 T25841 themeOf IL-1RA,decreased
R17555 T25833 T25843 themeOf IL-1RA,production
R17556 T25834 T25842 themeOf NFAT,Inhibition
R17557 T25835 T25842 themeOf NFIL-6,Inhibition
R17558 T25836 T25837 themeOf Inhibition,GP-induced
R17559 T25837 T25836 themeOf GP-induced,Inhibition
R17560 T25837 T25836 themeOf GP-induced,Inhibition
R17561 T25839 T25840 themeOf Inhibition,resulted
R17562 T25841 T25840 themeOf decreased,resulted
R17563 T25842 T25845 causeOf Inhibition,reduced
R17564 T25842 T25845 causeOf Inhibition,reduced
R17565 T25843 T25844 themeOf production,following
R17566 T25843 T25845 themeOf production,reduced
R17567 T25843 T25845 themeOf production,reduced

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue Negation Speculation
T26135 23496-23581 Negative_regulation denotes C, Inhibition of NFκB, NFAT and NFIL-6 significantly reduced the production of IL-1RA
T26134 23183-23204 Negative_regulation denotes a decrease in binding
T26133 23557-23581 Gene_expression denotes the production of IL-1RA
T26132 23316-23334 Negative_regulation denotes Inhibition of NFκB
T26131 22841-22897 Binding denotes NFκB, NFAT and NFIL-6 DNA binding to the IL-1RA promoter
T26130 23446-23466 Regulation denotes housekeeping control
T26129 23336-23340 Protein denotes NFAT
T26128 22847-22851 Protein denotes NFAT
T26127 23305-23308 Entity denotes n =
T26126 22882-22888 Protein denotes IL-1RA
T26125 23591-23615 Entity denotes PBMC following treatment
T26124 22875-22897 Entity denotes to the IL-1RA promoter
T26123 23364-23385 Protein denotes decreased IL-1RA mRNA
T26122 22959-22961 Protein denotes GP
T26121 23678-23679 Entity denotes p
T26120 22841-22845 Protein denotes NFκB
T26119 23327-23334 Protein denotes of NFκB
T26118 23055-23057 Protein denotes GP
T26117 23663-23664 Entity denotes p
T26116 23528-23534 Protein denotes NFIL-6
T26115 23037-23039 Protein denotes GP
T26114 22841-22866 Entity denotes NFκB, NFAT and NFIL-6 DNA
T26113 23483-23494 Entity denotes gel, n = 4)
T26112 23262-23267 Entity denotes = p <
T26111 23572-23581 Protein denotes of IL-1RA
T26110 23374-23380 Protein denotes IL-1RA
T26109 23513-23517 Protein denotes NFκB
T26108 23719-23722 Entity denotes n =
T26107 23345-23351 Protein denotes NFIL-6
T26106 22856-22862 Protein denotes NFIL-6
T26105 23073-23075 Protein denotes GP
T26104 23429-23434 Protein denotes GAPDH
T26103 23023-23039 Protein denotes CAPE, lane 5: GP
T26102 23154-23172 Entity denotes the NFATP2/3 site,
T26101 23519-23523 Protein denotes NFAT
T25391 21077-21101 Gene_expression denotes in generating more IL-1β
T25390 21357-21362 Protein denotes of GP
T25389 20913-20923 Protein denotes IL-1β/IL-1
T25388 21300-21306 Protein denotes TSST-1
T25387 20831-20833 Protein denotes RA
T25386 20995-21001 Entity denotes GP/LPS
T25385 21040-21043 Entity denotes LPS
T25384 21531-21534 Entity denotes n =
T25383 21014-21020 Protein denotes TSST-1
T25382 21027-21033 Protein denotes TSST-1
T25381 20821-20831 Protein denotes IL-1β/IL-1
T25380 21024-21038 Protein denotes GP/TSST-1 calc
T25379 20972-20987 Protein denotes LPS, TSST-1, GP
T25378 20990-21008 Entity denotes LPS, GP/LPS calc.,
T25377 21216-21246 Protein denotes the IL-1β/IL-1RA ratio over 48
T25376 21102-21122 Protein denotes than IL-1RA up to 24
T25375 21151-21154 Entity denotes LPS
T25374 20923-20925 Protein denotes RA
T25373 21319-21362 Entity denotes a pronounced anti-inflammatory action of GP
T25372 21461-21470 Protein denotes of IL-1RA
T25371 21141-21159 Protein denotes LPS or GP/LPS calc
T25370 20827-20831 Protein denotes IL-1
T25369 21266-21272 Protein denotes TSST-1
T25368 21430-21434 Entity denotes 24 h
T25367 20876-20885 Protein denotes to TSST-1
T25366 20972-20984 Entity denotes LPS, TSST-1,
T25365 20913-20923 Protein denotes IL-1β/IL-1
T25364 20995-21006 Protein denotes GP/LPS calc
T25363 21161-21166 Protein denotes vs GP
T25362 20919-20923 Protein denotes IL-1
T25361 21226-21230 Protein denotes IL-1
T25360 20821-20831 Protein denotes IL-1β/IL-1
T25359 21141-21144 Entity denotes LPS
T25358 21169-21172 Entity denotes LPS
T25357 21148-21154 Protein denotes GP/LPS
T25356 21479-21484 Protein denotes IL-1β
T25355 21220-21230 Protein denotes IL-1β/IL-1
T25354 21279-21285 Protein denotes TSST-1
T25353 21421-21425 Entity denotes 18 h
T25352 20995-21001 Protein denotes GP/LPS
T25351 21148-21154 Entity denotes GP/LPS
T25350 21053-21056 Entity denotes LPS
T25349 20900-20904 Entity denotes 48 h
T25348 20956-20966 Entity denotes human PBMC
T25347 21292-21297 Protein denotes vs GP
T25346 21220-21230 Protein denotes IL-1β/IL-1
T25345 21091-21101 Protein denotes more IL-1β
T25344 20977-20983 Protein denotes TSST-1
T25343 21266-21290 Protein denotes TSST-1 or GP/TSST-1 calc
T25342 20998-21001 Entity denotes LPS
T25341 20855-20861 Protein denotes TSST-1
T24710 19359-19365 Entity denotes GP/LPS
T24709 19085-19091 Protein denotes TSST-1
T24708 19108-19118 Entity denotes Human PBMC
T24707 19362-19365 Entity denotes LPS
T24706 19609-19615 Protein denotes TSST-1
T24705 19630-19645 Entity denotes LPS; lane 7: GP
T24704 19317-19370 Protein denotes Bars depicting the theoretical values for GP/LPS calc
T24703 19376-19390 Protein denotes GP/TSST-1 calc
T24702 18896-18910 Protein denotes TSST-1-induced
T24701 19004-19007 Entity denotes LPS
T24700 19160-19174 Protein denotes TSST-1, GP, GP
T24699 18953-18959 Protein denotes IL-1RA
T24698 19155-19158 Entity denotes LPS
T24697 19012-19014 Protein denotes GP
T24696 19379-19385 Protein denotes TSST-1
T24695 19359-19370 Protein denotes GP/LPS calc
T24694 19193-19212 Entity denotes LPS for 1 h at 37°C
T24693 19359-19365 Protein denotes GP/LPS
T24692 19284-19315 Entity denotes the site in the IL-1RA promoter
T24691 19596-19599 Entity denotes LPS
T24690 19160-19171 Protein denotes TSST-1, GP,
T24689 19300-19306 Protein denotes IL-1RA
T24688 19177-19183 Protein denotes TSST-1
T24687 19648-19654 Protein denotes TSST-1
T24686 18949-18968 Entity denotes the IL-1RA promoter
T24685 19017-19023 Protein denotes TSST-1
T24684 19255-19271 Protein denotes NFAT-DNA binding
T24683 19296-19315 Entity denotes the IL-1RA promoter
T24682 18999-19001 Protein denotes GP
T24681 18926-18968 Entity denotes a new NFATP2/3 site in the IL-1RA promoter
T23796 13095-13121 Gene_expression denotes a higher IL-1RA production
T23795 12480-12509 Gene_expression denotes IL-1β production following GP
T23794 12297-12321 Gene_expression denotes IL-1β production (pg/ml)
T23793 12854-12879 Gene_expression denotes IL-1RA production (pg/ml)
T23792 13006-13010 Entity denotes 48 h
T23791 12426-12429 Entity denotes LPS
T23790 12603-12614 Protein denotes GP/LPS calc
T23789 12794-12803 Entity denotes 12 h – 48
T23788 12382-12391 Protein denotes ng TSST-1
T23787 12845-12849 Entity denotes 48 h
T23786 12288-12292 Entity denotes 48 h
T23785 12410-12416 Entity denotes ng LPS
T23784 12297-12302 Protein denotes IL-1β
T23783 13267-13281 Protein denotes GP/TSST-1 calc
T23782 13250-13261 Protein denotes GP/LPS calc
T23781 12437-12438 Entity denotes h
T23780 12956-12962 Protein denotes TSST-1
T23779 13270-13276 Protein denotes TSST-1
T23778 12925-12934 Protein denotes 100 μg GP
T23777 12984-12987 Entity denotes LPS
T23776 12243-12249 Protein denotes TSST-1
T23775 13104-13110 Protein denotes IL-1RA
T23774 12606-12609 Entity denotes LPS
T23773 12759-12783 Protein denotes exaggerated following GP
T23772 12533-12542 Protein denotes to TSST-1
T23771 12548-12549 Entity denotes p
T23770 12968-12974 Entity denotes ng LPS
T23769 12264-12273 Protein denotes to TSST-1
T23768 12603-12609 Protein denotes GP/LPS
T23767 12480-12485 Protein denotes IL-1β
T23766 13000-13001 Entity denotes h
T23765 12854-12860 Protein denotes IL-1RA
T23764 12186-12194 Protein denotes A, IL-1β
T23763 12786-12806 Protein denotes TSST-1 (12 h – 48 h)
T23762 12398-12404 Protein denotes TSST-1
T23761 12623-12629 Protein denotes TSST-1
T23760 13297-13303 Protein denotes IL-1RA
T23759 13250-13256 Entity denotes GP/LPS
T23758 12883-12893 Entity denotes human PBMC
T23757 12603-12609 Entity denotes GP/LPS
T23756 13054-13060 Protein denotes TSST-1
T23755 12512-12518 Protein denotes TSST-1
T23754 12652-12657 Protein denotes IL-1β
T23753 13253-13256 Entity denotes LPS
T23752 12215-12226 Entity denotes 12 h – 24 h
T23751 12940-12949 Protein denotes ng TSST-1
T23750 12325-12335 Entity denotes human PBMC
T23749 12446-12447 Entity denotes h
T23748 12367-12376 Protein denotes 100 μg GP
T23747 12737-12740 Entity denotes n =
T23746 12745-12754 Protein denotes B, IL-1RA
T23745 12215-12224 Entity denotes 12 h – 24
T23744 13036-13043 Entity denotes of PBMC
T23743 13250-13256 Protein denotes GP/LPS
T23742 13195-13196 Entity denotes p
T23741 12620-12634 Protein denotes GP/TSST-1 calc
T23740 13176-13182 Protein denotes TSST-1
T23739 12794-12805 Entity denotes 12 h – 48 h
T23738 12821-12830 Protein denotes to TSST-1
T24129 18671-18702 Protein denotes to LPS, TSST-1, GP, GP/LPS calc
T24128 18679-18689 Protein denotes TSST-1, GP
T24127 18671-18702 Entity denotes to LPS, TSST-1, GP, GP/LPS calc
T24126 18644-18646 Protein denotes GP
T24125 18710-18716 Protein denotes TSST-1
T24124 18636-18639 Entity denotes LPS
T24123 18539-18545 Protein denotes TSST-1
T24122 18517-18519 Protein denotes GP
T24121 18589-18595 Protein denotes IL-1RA
T24120 18530-18534 Entity denotes LPS-
T24119 18562-18604 Entity denotes to a new NFκB3 site in the IL-1RA promoter
T24118 18679-18686 Protein denotes TSST-1,
T24117 18674-18690 Entity denotes LPS, TSST-1, GP,
T24116 18585-18604 Entity denotes the IL-1RA promoter
T24115 18649-18655 Protein denotes TSST-1
T24114 18631-18633 Protein denotes GP
T22816 10313-10347 Positive_regulation denotes the DNA binding proteins activated
T22815 10694-10698 Entity denotes PBMC
T22814 10713-10717 Protein denotes NFκB
T22813 10740-10742 Protein denotes c1
T22812 10232-10241 Protein denotes NFATc2/c1
T22811 10594-10607 Protein denotes NFκB p50, p65
T22810 10220-10227 Protein denotes p65/p50
T22809 10556-10567 Entity denotes PMA-treated
T22808 10220-10227 Protein denotes p65/p50
T22807 10519-10523 Protein denotes NFκB
T22806 10594-10607 Protein denotes NFκB p50, p65
T22805 10731-10738 Protein denotes NFAT c2
T22804 10498-10527 Protein denotes recombinant proteins NFκB p52
T22803 10232-10241 Protein denotes NFATc2/c1
T22802 10239-10241 Protein denotes c1
T22801 10731-10735 Protein denotes NFAT
T22800 10536-10580 Entity denotes nuclear extracts of PMA-treated Jurkat cells
T22799 10313-10337 Protein denotes the DNA binding proteins
T22798 10529-10534 Protein denotes c-rel
T22797 10351-10353 Protein denotes GP
T22796 10624-10626 Protein denotes c2
T22795 10723-10726 Protein denotes p50
T22794 10370-10374 Protein denotes NFκB
T22793 10616-10627 Protein denotes NFATc1, c2)
T22792 10713-10721 Protein denotes NFκB p65
T22791 10556-10580 Entity denotes PMA-treated Jurkat cells
T22790 10663-10679 Entity denotes nuclear extracts
T22789 10599-10603 Protein denotes p50,
T22788 10498-10527 Protein denotes recombinant proteins NFκB p52
T22787 10379-10383 Protein denotes NFAT
T22786 10224-10227 Protein denotes p50
T22785 10773-10774 Entity denotes n
T22259 9747-9758 Protein denotes GP (100 μg)
T22258 9380-9383 Entity denotes DNA
T22257 9167-9176 Protein denotes NFκB-IL-8
T22256 9676-9682 Protein denotes TSST-1
T22255 8993-8997 Protein denotes NFκB
T22254 9220-9231 Protein denotes IFNγ, TNFα,
T22253 9213-9260 Protein denotes to the IFNγ, TNFα, IL-6 and IL-8 gene promoters
T22252 9734-9737 Entity denotes LPS
T22251 9016-9020 Entity denotes PBMC
T22250 9739-9762 Protein denotes TSST-1, GP (100 μg), GP
T22249 9157-9163 Protein denotes NFIL-6
T22248 9926-9943 Protein denotes GP (1 and 100 μg)
T22247 9226-9230 Protein denotes TNFα
T22246 9094-9101 Entity denotes Nuclear
T22245 9213-9260 Entity denotes to the IFNγ, TNFα, IL-6 and IL-8 gene promoters
T22244 10060-10066 Protein denotes TSST-1
T22243 9687-9697 Entity denotes Human PBMC
T22242 9506-9510 Protein denotes p50,
T22241 9356-9366 Entity denotes NFIL-6-DNA
T22240 9346-9354 Entity denotes NFκB-DNA
T22239 9002-9008 Protein denotes NFIL-6
T22238 9370-9374 Protein denotes NFκB
T22237 9636-9638 Protein denotes GP
T22236 9781-9800 Entity denotes LPS for 1 h at 37°C
T22235 9890-9906 Protein denotes NFκB-DNA binding
T22234 9167-9192 Entity denotes NFκB-IL-8 oligonucleotide
T22233 9621-9625 Protein denotes NFκB
T22232 8987-8991 Protein denotes NFAT
T22231 9332-9344 Entity denotes the NFAT-DNA
T22230 9661-9667 Protein denotes TSST-1
T22229 9081-9084 Entity denotes 1 h
T22228 10057-10071 Protein denotes GP/TSST-1 calc
T22227 9167-9176 Protein denotes NFκB-IL-8
T22226 9765-9771 Protein denotes TSST-1
T22225 9947-9953 Protein denotes TSST-1
T22224 9375-9379 Protein denotes IL-8
T22223 9172-9176 Protein denotes IL-8
T22222 9641-9648 Protein denotes TSST-1,
T22221 9346-9354 Protein denotes NFκB-DNA
T22220 9102-9110 Entity denotes extracts
T22219 9241-9245 Protein denotes IL-8
T22218 9370-9391 Entity denotes NFκB-IL-8-DNA complex
T22217 9739-9759 Protein denotes TSST-1, GP (100 μg),
T22216 9151-9155 Protein denotes NFκB
T22215 9145-9149 Protein denotes NFAT
T22214 9232-9236 Protein denotes IL-6
T20946 38830-38886 Binding denotes binding of transcription factors to the IL-1RA promoter,
T20945 39569-39598 Transcription denotes messenger RNA was transcribed
T20944 39569-39598 Transcription denotes messenger RNA was transcribed
T20943 39506-39515 Localization denotes PBMC RNA
T20942 38765-38800 Negative_regulation denotes Inhibition of transcription factors
T20941 39932-39946 Protein denotes IL-1RA protein
T20940 38925-38952 Entity denotes of the following substances
T20939 38887-38891 Entity denotes PBMC
T20938 39472-39477 Entity denotes sites
T20937 39423-39426 Protein denotes GGC
T20936 39907-39911 Entity denotes 18 h
T20935 39963-40017 Entity denotes the supernatant by ELISA after 24 h incubation with GP
T20934 38838-38862 Protein denotes of transcription factors
T20933 38776-38800 Protein denotes of transcription factors
T20932 39423-39450 Protein denotes GGC GCA GAA AAG GTA AAA TAT
T20931 39506-39514 Protein denotes PBMC RNA
T20930 39682-39687 Protein denotes GAPDH
T20929 39671-39722 Protein denotes IL-1RA and GAPDH transcripts by PCR with a HotStart
T20928 39384-39391 Protein denotes ATT GCG
T20927 39174-39223 Entity denotes 10 μg/ml cycloheximide (Santa Cruz Biotechnology)
T20926 39420-39421 Protein denotes 3
T20925 39506-39510 Entity denotes PBMC
T20924 39307-39309 Protein denotes GP
T20923 39360-39366 Protein denotes NFIL-6
T20922 39423-39450 Protein denotes GGC GCA GAA AAG GTA AAA TAT
T20921 38870-38876 Protein denotes IL-1RA
T20920 39423-39450 Entity denotes GGC GCA GAA AAG GTA AAA TAT
T20919 39413-39421 Protein denotes NFATP2/3
T20918 39994-39998 Entity denotes 24 h
T20917 38866-38886 Entity denotes the IL-1RA promoter,
T20916 39714-39717 Protein denotes Hot
T20915 39396-39407 Protein denotes CTT AGT GGG
T20914 38911-38952 Entity denotes 1 h with each of the following substances
T20913 39569-39582 Protein denotes messenger RNA
T20912 39890-39895 Protein denotes GAPDH
T20911 39102-39152 Entity denotes ng/ml cyclosporin A (Calbiochem-Merck Biosciences,
T20910 39396-39407 Entity denotes CTT AGT GGG
T20909 39485-39504 Entity denotes the IL-1RA promoter
T20908 39671-39677 Protein denotes IL-1RA
T20907 39928-39930 Protein denotes GP
T20906 39287-39309 Entity denotes 1 h incubation with GP
T20905 39413-39421 Protein denotes NFATP2/3
T20904 39427-39430 Protein denotes GCA
T20903 39249-39251 Protein denotes GP
T20902 39435-39438 Entity denotes AAG
T20901 38920-38952 Entity denotes each of the following substances
T20900 39703-39706 Protein denotes PCR
T20899 39253-39257 Entity denotes Band
T20898 39489-39495 Protein denotes IL-1RA
T20897 39932-39938 Protein denotes IL-1RA
T20896 39811-39817 Protein denotes IL-1RA
T20895 39455-39458 Entity denotes CTA
T20894 39731-39734 Protein denotes PCR
T21360 40422-40428 Protein denotes TSST-1
T21359 40707-40713 Protein denotes TSST-1
T21358 40099-40115 Protein denotes cytokine amounts
T21357 40720-40726 Protein denotes TSST-1
T21356 40435-40441 Protein denotes TSST-1
T21355 40142-40163 Protein denotes transcription factors
T21354 40610-40627 Entity denotes example GP vs LPS
T21353 40422-40446 Protein denotes TSST-1 vs GP/TSST-1 calc
T21352 40610-40627 Entity denotes example GP vs LPS
T21351 40754-40769 Entity denotes the Student's t
T21350 40707-40731 Protein denotes TSST-1 vs GP/TSST-1 calc
T20205 38685-38731 Regulation denotes donors showing no spontaneous cytokine release
T20204 38648-38762 Positive_regulation denotes Only stimulation of PBMC observed in donors showing no spontaneous cytokine release was included in the statistics
T20203 38339-38346 Protein denotes of IL-1
T20202 38665-38672 Entity denotes of PBMC
T20201 38295-38302 Protein denotes of IL-2
T20200 38055-38059 Protein denotes TNFα
T20199 37891-37920 Entity denotes Supernatants of cell cultures
T20198 38715-38723 Protein denotes cytokine
T20197 38070-38074 Protein denotes IL-6
T20196 38458-38471 Protein denotes All cytokines
T20195 38582-38598 Protein denotes Cytokine amounts
T20194 38061-38065 Protein denotes IL-1
T20193 38049-38053 Protein denotes IFNγ
T20192 37869-37890 Protein denotes Cytokine measurements
T20191 38145-38151 Protein denotes IL-1RA
T20190 38228-38234 Protein denotes TGFβ 1
T20189 38156-38160 Protein denotes IL-8
T19688 37109-37116 Entity denotes sc-109,
T19687 36967-36980 Protein denotes c-Rel (61 kD)
T19686 37354-37369 Entity denotes AP-conjugate sc
T19685 37016-37030 Entity denotes PMA-stimulated
T19684 36839-36849 Entity denotes antibodies
T19683 36636-36660 Protein denotes the DNA binding proteins
T19682 37212-37225 Protein denotes NFATc2 (M-20)
T19681 37091-37108 Protein denotes anti-NFκB p65 (A)
T19680 37186-37198 Protein denotes c-rel (N466)
T19679 37749-37759 Protein denotes PBS/1% BSA
T19678 37263-37296 Protein denotes two goat polyclonal IgG1 antisera
T19677 37063-37082 Protein denotes anti-NFκB p50 (NLS)
T19676 37193-37197 Entity denotes N466
T19675 37423-37443 Protein denotes The nuclear proteins
T19674 37640-37651 Protein denotes PBS/1% BSA,
T19673 36710-36713 Protein denotes SRC
T19672 36992-37014 Entity denotes Jurkat nuclear extract
T19671 37181-37201 Entity denotes anti-c-rel (N466) sc
T19670 36677-36681 Protein denotes NFκB
T19669 37298-37331 Entity denotes secondary antibodies (0.8 μg/dot)
T19668 37229-37246 Protein denotes 1151, anti-NFATc1
T19667 37248-37252 Protein denotes K-18
T19666 36708-36729 Protein denotes a SRC96D SNS minifold
T19665 36686-36691 Protein denotes NFAT,
T19664 37611-37621 Entity denotes antibodies
T19663 37032-37061 Entity denotes primary antibodies (1 μg/dot)
T19662 37202-37228 Entity denotes 272, anti-NFATc2 (M-20) sc
T19661 37145-37179 Protein denotes a rabbit polyclonal IgG1 antiserum
T19660 37519-37529 Protein denotes PBS/3% BSA
T19659 37354-37369 Entity denotes AP-conjugate sc
T19658 37109-37139 Entity denotes sc-109, anti-NFκB p52 (447) sc
T19657 36944-36955 Protein denotes p52 (80 kD)
T19656 37684-37738 Entity denotes the alkaline phosphatase-conjugated secondary antibody
T19655 37127-37136 Protein denotes p52 (447)
T19654 36939-36958 Protein denotes NFκB p52 (80 kD) sc
T19160 36188-36228 Binding denotes non-specific binding to nuclear proteins
T19159 36103-36132 Binding denotes the cytokine promoter binding
T19158 36396-36402 Protein denotes p65/50
T19157 36503-36515 Protein denotes of Oct-1 DNA
T19156 36375-36379 Protein denotes NFκB
T19155 36209-36228 Protein denotes to nuclear proteins
T19154 36300-36323 Entity denotes to the nuclear extracts
T19153 36396-36402 Protein denotes p65/50
T19152 36116-36124 Entity denotes promoter
T19151 36103-36132 Protein denotes the cytokine promoter binding
T19150 35736-35752 Entity denotes nuclear extracts
T19149 36517-36540 Entity denotes unrelated DNA, Table 1)
T19148 36353-36370 Entity denotes supershift assays
T19147 36188-36228 Entity denotes non-specific binding to nuclear proteins
T19146 36400-36402 Protein denotes 50
T19145 36403-36411 Entity denotes antibody
T19144 36503-36515 Entity denotes of Oct-1 DNA
T19143 35802-35836 Entity denotes Nuclear extracts of purified PBMCs
T19142 35822-35836 Entity denotes purified PBMCs
T19141 36133-36150 Entity denotes sites (see above)
T18755 35484-35564 Regulation denotes which seem to be crucial for the binding of NFAT and NFκB proteins, respectively
T18754 35509-35550 Binding denotes for the binding of NFAT and NFκB proteins
T18753 34868-34872 Protein denotes TNFα
T18752 35537-35541 Protein denotes NFκB
T18751 35631-35642 Entity denotes Probe Quant
T18750 35410-35435 Entity denotes of the TNFα promoter [55]
T18749 35355-35377 Entity denotes the IFNγ promoter [29]
T18748 34889-34893 Protein denotes IL-6
T18747 35113-35127 Entity denotes Polynucleotide
T18746 34747-34772 Entity denotes Oligonucleotides (Oligos)
T18745 35417-35421 Protein denotes TNFα
T18744 34880-34884 Protein denotes IFNγ
T18743 35525-35550 Protein denotes of NFAT and NFκB proteins
T18742 35140-35143 Protein denotes PNK
T18741 35578-35591 Entity denotes the ds oligos
T18740 35359-35363 Protein denotes IFNγ
T18739 35128-35134 Protein denotes Kinase
T18738 35340-35390 Entity denotes the P2 site of the IFNγ promoter [29] and in the κ
T18737 34864-34903 Entity denotes the TNFα, IL-8, IFNγ and IL-6 promoters
T18736 34874-34878 Protein denotes IL-8
T18735 35140-35147 Protein denotes PNK Kit
T18734 35610-35613 Entity denotes gel
T18733 34829-34831 Entity denotes ds
T18732 34833-34858 Entity denotes oligonucleotides (oligos)
T18731 35528-35532 Protein denotes NFAT
T18730 35097-35138 Protein denotes the Ready-To-Go-Polynucleotide-Kinase Kit
T18228 34526-34586 Entity denotes wild-type LPS from Escherichia coli serotype 0111:B4 (Sigma,
T18227 34734-34736 Protein denotes GP
T18226 34384-34393 Entity denotes h (ELISA)
T18225 34355-34365 Entity denotes 1 h (EMSA)
T18224 34199-34208 Protein denotes cytokines
T18223 34252-34272 Protein denotes sterile pyrogen-free
T18222 34454-34481 Protein denotes TSST-1 (Toxin Technologies,
T18221 34210-34214 Entity denotes PBMC
T18220 34702-34708 Protein denotes TSST-1
T18219 34635-34639 Entity denotes PBMC
T18218 34580-34585 Protein denotes Sigma
T18217 34462-34467 Entity denotes Toxin
T18216 34428-34430 Protein denotes GP
T18215 34741-34744 Entity denotes LPS
T18214 34520-34525 Entity denotes cells
T18213 34437-34490 Entity denotes 250 ng/106 cells TSST-1 (Toxin Technologies, Sarasota
T18212 34695-34697 Protein denotes GP
T17930 34031-34044 Entity denotes 1% penicillin
T17929 34094-34130 Entity denotes 1% 200 mM L-glutamine (BioWhittaker)
T17928 33400-33413 Entity denotes of human PBMC
T17927 33706-33710 Entity denotes PBMC
T17926 33814-33817 Entity denotes gel
T17925 34059-34089 Entity denotes 1% streptomycin (10000 μg/ml),
T17924 33989-33996 Entity denotes low-LPS
T17923 33923-33931 Entity denotes LPS-free
T17615 33033-33035 Protein denotes GP
T17614 32988-33052 Entity denotes Water soluble phosphorylated β-1→3-D-glucan (GP) was prepared as
T17613 33338-33347 Entity denotes endotoxin
T17612 33240-33249 Entity denotes endotoxin
T17452 32279-32309 Binding denotes a transcription factor binding
T17451 32946-32950 Protein denotes IL-1
T17450 32654-32660 Protein denotes IL-1RA
T17449 32377-32383 Protein denotes TSST-1
T17448 32454-32499 Entity denotes an IL-1RA-mediated anti-inflammatory reaction
T17447 32721-32742 Entity denotes a fungal carbohydrate
T16941 30530-30569 Gene_expression denotes of the TSST-1-induced IL-1RA production
T16940 25363-25425 Binding denotes NFIL-6 [13,39] or NFATc2 dimer binding to the IL-8κB site [38]
T16939 28789-28882 Binding denotes Accordingly, we found that the TSST-1-induced binding of NFκB to sites from the TNFα promoter
T16938 24271-24310 Binding denotes binding of NFκB-, NFIL-6- and NFAT-mers
T16937 27408-27435 Binding denotes binding to MHC-II molecules
T16936 30352-30386 Positive_regulation denotes increase in TSST-1-induced binding
T16935 25788-25816 Positive_regulation denotes that GP did not induce IL-1β true
T16934 25788-25816 Gene_expression denotes that GP did not induce IL-1β true
T16933 29545-29566 Binding denotes conserved nucleotides
T16932 25233-25267 Transcription denotes the GP-mediated IL-8 transcription
T16931 25154-25156 Protein denotes 65
T16930 25861-25907 Entity denotes an immediate anti-inflammatory potential of GP
T16929 24618-24650 Protein denotes a very limited cytokine response
T16928 26126-26134 Protein denotes NFATP2/3
T16927 27539-27559 Entity denotes PI3K and p38 mitogen
T16926 31338-31341 Entity denotes LPS
T16925 26497-26505 Entity denotes to sites
T16924 27457-27463 Entity denotes T cell
T16923 28537-28546 Protein denotes of IL-1RA
T16922 31843-31852 Protein denotes GP (PI3K)
T16921 29432-29438 Protein denotes IL-1RA
T16920 25350-25354 Protein denotes NFκB
T16919 29944-29968 Entity denotes the IL-1RA promoter [30]
T16918 28945-28959 Protein denotes TSST-1-induced
T16917 29349-29353 Protein denotes TNFα
T16916 28097-28143 Protein denotes than the specific cytokine panel induced by GP
T16915 31847-31851 Protein denotes PI3K
T16914 27360-27394 Protein denotes bacterial superantigen like TSST-1
T16913 31203-31214 Entity denotes LPS-induced
T16912 26543-26554 Protein denotes IL-1RA mRNA
T16911 23900-23922 Protein denotes PI3K-signaling [22,37]
T16910 26886-26895 Entity denotes monocytes
T16909 24473-24477 Protein denotes NFAT
T16908 28386-28390 Protein denotes IL-1
T16907 25184-25204 Entity denotes p65/50 heterodimers,
T16906 25764-25767 Entity denotes LPS
T16905 31857-31860 Entity denotes LPS
T16904 29545-29566 Entity denotes conserved nucleotides
T16903 28843-28850 Protein denotes of NFκB
T16902 30552-30558 Protein denotes IL-1RA
T16901 31391-31407 Protein denotes the PI3K pathway
T16900 25150-25156 Protein denotes p65/65
T16899 27416-27435 Entity denotes to MHC-II molecules
T16898 30474-30482 Protein denotes NFATP2/3
T16897 29948-29954 Protein denotes IL-1RA
T16896 30408-30412 Protein denotes NFκB
T16895 31972-31986 Protein denotes of similar PRR
T16894 30537-30551 Protein denotes TSST-1-induced
T16893 24142-24144 Protein denotes GP
T16892 32065-32085 Protein denotes DNA-binding proteins
T16891 28414-28434 Entity denotes an anti-inflammatory
T16890 31639-31643 Protein denotes PI3K
T16889 26034-26038 Protein denotes NFκB
T16888 31862-31879 Entity denotes mitogen-activated
T16887 28759-28764 Protein denotes IL-1β
T16886 27188-27194 Entity denotes of LPS
T16885 27660-27688 Entity denotes the anti-inflammatory IL-1RA
T16884 24963-24969 Protein denotes of p50
T16883 29226-29231 Protein denotes by GP
T16882 25283-25287 Protein denotes IL-8
T16881 26780-26791 Entity denotes neutrophils
T16880 30232-30241 Entity denotes this site
T16879 25842-25849 Protein denotes IL-1RA,
T16878 30423-30427 Entity denotes site
T16877 28466-28471 Protein denotes IL-1β
T16876 25249-25253 Protein denotes IL-8
T16875 30885-30895 Protein denotes IL-1β/IL-1
T16874 26421-26427 Protein denotes IL-1RA
T16873 30464-30487 Entity denotes the novel NFATP2/3 site
T16872 24073-24092 Entity denotes of human leukocytes
T16871 30891-30895 Protein denotes IL-1
T16870 30885-30895 Protein denotes IL-1β/IL-1
T16869 28774-28778 Protein denotes IFNγ
T16868 28643-28647 Protein denotes NFκB
T16867 26248-26249 Protein denotes 3
T16866 28138-28143 Protein denotes by GP
T16865 25788-25795 Protein denotes that GP
T16864 30474-30482 Protein denotes NFATP2/3
T16863 28380-28390 Protein denotes IL-1β/IL-1
T16862 28713-28717 Protein denotes IL-8
T16861 30045-30046 Protein denotes 3
T16860 28617-28631 Protein denotes TSST-1 induced
T16859 26989-27021 Protein denotes This GP-induced cytokine profile
T16858 30668-30678 Protein denotes IL-1β/IL-1
T16857 30805-30810 Protein denotes IL-1β
T16856 31586-31591 Protein denotes sIL-1
T16855 31763-31773 Protein denotes PI3K [50],
T16854 31346-31352 Protein denotes TSST-1
T16853 26933-26937 Protein denotes IL-8
T16852 26421-26436 Entity denotes IL-1RA promoter
T16851 28869-28873 Protein denotes TNFα
T16850 28960-28966 Protein denotes IL-1RA
T16849 25574-25578 Protein denotes TNFα
T16848 25771-25787 Protein denotes TSST-1, we found
T16847 27272-27289 Protein denotes the NFκB pathway,
T16846 30145-30153 Protein denotes the LPS-
T16845 28990-28991 Entity denotes p
T16844 25350-25358 Protein denotes NFκB p65
T16843 30364-30378 Protein denotes TSST-1-induced
T16842 27503-27507 Protein denotes IFNγ
T16841 29288-29296 Entity denotes the LPS-
T16840 30678-30680 Protein denotes RA
T16839 25919-25943 Entity denotes the IL-1RA promoter [34]
T16838 30025-30067 Entity denotes an inhibitory NFκB2/3 site (-288 and -302)
T16837 27548-27551 Protein denotes p38
T16836 29700-29718 Entity denotes a T on position 10
T16835 31362-31368 Protein denotes TSST-1
T16834 30481-30482 Protein denotes 3
T16833 31064-31078 Protein denotes TSST-1-induced
T16832 27161-27167 Protein denotes TSST-1
T16831 25184-25204 Protein denotes p65/50 heterodimers,
T16830 27388-27394 Protein denotes TSST-1
T16829 31095-31099 Protein denotes IL-2
T16828 26900-26911 Entity denotes neutrophils
T16827 28380-28390 Protein denotes IL-1β/IL-1
T16826 26031-26069 Entity denotes an NFκB consensus site (-266 and -280)
T16825 26513-26519 Protein denotes IL-1RA
T16824 26716-26719 Protein denotes Fig
T16823 28722-28728 Protein denotes IL-1RA
T16822 24668-24684 Protein denotes IL-1RA (Fig. 3B)
T16821 25150-25156 Protein denotes p65/65
T16820 26509-26528 Entity denotes the IL-1RA promoter
T16819 29753-29757 Protein denotes TNFα
T16818 25923-25929 Protein denotes IL-1RA
T16817 31463-31465 Protein denotes GP
T16816 24931-24939 Protein denotes NFκB p65
T16815 24659-24663 Protein denotes IL-8
T16814 24282-24287 Protein denotes NFκB-
T16813 24931-24935 Protein denotes NFκB
T16812 25363-25377 Protein denotes NFIL-6 [13,39]
T16811 28194-28197 Entity denotes LPS
T16810 30790-30799 Protein denotes of IL-1RA
T16809 31111-31131 Entity denotes of murine EL-4 cells
T16808 27539-27543 Protein denotes PI3K
T16807 28476-28480 Protein denotes IL-6
T16806 25363-25425 Entity denotes NFIL-6 [13,39] or NFATc2 dimer binding to the IL-8κB site [38]
T16805 28649-28655 Protein denotes NFIL-6
T16804 28749-28787 Entity denotes the TNFα, IL-1β, IL-6 or IFNγ promoter
T16803 28816-28826 Protein denotes the TSST-1
T16802 25095-25099 Protein denotes IL-8
T16801 29425-29447 Entity denotes of the IL-1RA promoter
T16800 26241-26249 Protein denotes NFATP2/3
T16799 31880-31886 Protein denotes kinase
T16798 26588-26598 Entity denotes inhibitors
T16797 24797-24803 Protein denotes IL-1RA
T16796 31548-31564 Protein denotes the PI3K pathway
T16795 27743-27747 Protein denotes PAMP
T16794 26402-26410 Protein denotes the IFNγ
T16793 27453-27472 Protein denotes the T cell receptor
T16792 25811-25816 Protein denotes IL-1β
T16791 29183-29187 Protein denotes NFκB
T16790 25188-25190 Protein denotes 50
T16789 31706-31718 Entity denotes T cells [49]
T16788 24289-24295 Protein denotes NFIL-6
T16787 28684-28737 Entity denotes now unknown sites within the IL-8 and IL-1RA promoter
T16786 25583-25588 Protein denotes IL-1β
T16785 28365-28379 Protein denotes TSST-1-induced
T16784 26412-26416 Protein denotes IL-6
T16783 29064-29084 Entity denotes the IL-1RA promoter,
T16782 25000-25004 Protein denotes IL-8
T16781 27222-27242 Protein denotes Toll-like receptor 4
T16780 30433-30439 Protein denotes NFIL-6
T16779 31602-31607 Protein denotes IL-1β
T16778 27689-27717 Entity denotes by fungal carbohydrates (GP)
T16777 29589-29607 Protein denotes the decameric NFκB
T16776 26085-26086 Protein denotes 3
T16775 25402-25425 Entity denotes to the IL-8κB site [38]
T16774 30851-30855 Protein denotes IL-1
T16773 31720-31738 Protein denotes Activation of NFκB
T16772 27069-27072 Entity denotes LPS
T16771 25015-25019 Protein denotes Figs
T16770 28865-28882 Entity denotes the TNFα promoter
T16769 25157-25166 Entity denotes homodimer
T16768 29305-29319 Protein denotes TSST-1-induced
T16767 28851-28882 Entity denotes to sites from the TNFα promoter
T16766 24053-24061 Protein denotes cytokine
T16765 23820-23822 Protein denotes GP
T16764 31988-31991 Entity denotes LPS
T16763 29852-29898 Entity denotes of the new NFκB consensus site (-266 and -280)
T16762 29643-29662 Entity denotes the IL-1RA promoter
T16761 31537-31547 Entity denotes leukocytes
T16760 26001-26029 Entity denotes site (between -100 and -130)
T16759 28753-28757 Protein denotes TNFα
T16758 25381-25387 Protein denotes NFATc2
T16757 29707-29718 Entity denotes position 10
T16756 25959-25990 Entity denotes four new binding sites (Fig. 8)
T16755 31193-31195 Protein denotes GP
T16754 26133-26134 Protein denotes 3
T16753 29068-29074 Protein denotes IL-1RA
T16752 30158-30172 Protein denotes TSST-1-induced
T16751 30668-30678 Protein denotes IL-1β/IL-1
T16750 26254-26273 Protein denotes NFIL-6 DNA binding,
T16749 26543-26549 Protein denotes IL-1RA
T16748 26559-26566 Protein denotes protein
T16747 26241-26249 Protein denotes NFATP2/3
T16746 31586-31593 Protein denotes sIL-1RA
T16745 26705-26714 Protein denotes of IL-1RA
T16744 28660-28664 Protein denotes NFAT
T16743 26759-26791 Entity denotes monocytes as well as neutrophils
T16742 28709-28737 Entity denotes the IL-8 and IL-1RA promoter
T16741 25499-25515 Protein denotes p65 binding half
T16740 26822-26833 Protein denotes IL-1RA [32]
T16739 29092-29103 Protein denotes the TSST-1-
T16738 24314-24332 Entity denotes cytokine promoters
T16737 29175-29202 Entity denotes the new NFκB consensus site
T16736 27570-27576 Protein denotes kinase
T16735 29630-29638 Protein denotes the TNFα
T16734 27347-27356 Protein denotes TNFα [43]
T16733 25555-25597 Entity denotes site described for TNFα and IL-1β [27,40],
T16732 29048-29058 Entity denotes NFκB sites
T16731 25516-25520 Entity denotes site
T16730 26204-26213 Protein denotes of IL-1RA
T16729 26126-26134 Protein denotes NFATP2/3
T16728 24993-25013 Entity denotes of the IL-8 promoter
T16727 27076-27083 Protein denotes TSST-1,
T16726 28201-28207 Protein denotes TSST-1
T16725 28390-28392 Protein denotes RA
T16724 29647-29653 Protein denotes IL-1RA
T16723 27512-27516 Protein denotes TNFα
T16722 26388-26392 Protein denotes NFAT
T16721 30674-30678 Protein denotes IL-1
T16720 25447-25472 Entity denotes The IL-8κB consensus site
T16719 26473-26477 Protein denotes NFAT
T16718 32024-32030 Protein denotes IL-1RA
T16717 26464-26471 Protein denotes of NFκB
T16716 27660-27688 Protein denotes the anti-inflammatory IL-1RA
T16715 30702-30708 Protein denotes TSST-1
T16714 24301-24310 Protein denotes NFAT-mers
T16713 31080-31094 Protein denotes IL-1-dependent
T16712 26181-26183 Protein denotes GP
T16711 29863-29867 Protein denotes NFκB
T16710 27156-27159 Entity denotes LPS
T16709 29528-29532 Protein denotes NFκB
T16708 29149-29163 Protein denotes TSST-1-induced
T16707 24301-24310 Protein denotes NFAT-mers
T16706 30919-30925 Protein denotes TSST-1
T16705 30881-30897 Protein denotes the IL-1β/IL-1RA
T16704 26071-26107 Entity denotes another NFκB2/3 site (-288 and -302)
T16703 31996-32009 Entity denotes peptidoglycan
T16702 26946-26952 Protein denotes IL-1RA
T16701 28766-28770 Protein denotes IL-6
T16700 32020-32035 Protein denotes the IL-1RA gene
T16699 29342-29362 Entity denotes of the TNFα promoter
T16698 27625-27655 Protein denotes the neutrophil-attracting IL-8
T16697 26112-26155 Entity denotes a more distal NFATP2/3 site (-471 and -490)
T16696 24314-24332 Protein denotes cytokine promoters
T16695 23891-23896 Protein denotes NFκB-
T16694 31695-31702 Protein denotes of NFAT
T16693 30429-30449 Entity denotes the NFIL-6 site [32]
T16692 24752-24782 Protein denotes a β-1→3-D-glucan-mediated IL-8
T16691 24383-24387 Protein denotes NFAT
T16690 29678-29684 Protein denotes IL-1RA
T16689 30993-30998 Protein denotes IL-1β
T16688 26482-26528 Protein denotes NFIL-6 binding to sites in the IL-1RA promoter
T16687 29048-29052 Protein denotes NFκB
T16686 29404-29408 Protein denotes NFκB
T11234 21781-21825 Negative_regulation denotes an inhibition of NFκB via CAPE [35] and CyA,
T11233 21540-21604 Negative_regulation denotes Inhibition of transcription factors led to reduced IL-1RA levels
T11232 22234-22267 Binding denotes the NFκB and NFIL-6 binding sites
T11231 22234-22267 Entity denotes the NFκB and NFIL-6 binding sites
T11230 22653-22657 Protein denotes NFκB
T11229 22460-22466 Protein denotes IL-1RA
T11228 21700-21719 Entity denotes the IL-1RA promoter
T11227 21974-21980 Protein denotes IL-1RA
T11226 22382-22383 Entity denotes h
T11225 22023-22044 Protein denotes IL-1RA protein levels
T11224 22528-22531 Protein denotes Fig
T11223 21970-21987 Entity denotes the IL-1RA sites,
T11222 22411-22511 Entity denotes A representative gel demonstrating a decrease in IL-1RA mRNA after inhibition with CAPE, CyA and CHX
T11221 22603-22610 Entity denotes h of GP
T11220 21621-21631 Entity denotes inhibitors
T11219 22007-22013 Protein denotes IL-1RA
T11218 22046-22049 Protein denotes Fig
T11217 21704-21710 Protein denotes IL-1RA
T11216 21795-21802 Protein denotes of NFκB
T11215 22247-22253 Protein denotes NFIL-6
T11214 22238-22242 Protein denotes NFκB
T11213 22352-22356 Protein denotes mRNA
T11212 22402-22409 Entity denotes h of GP
T11211 22537-22538 Entity denotes n
T11210 22572-22602 Protein denotes IL-1RA protein levels after 24
T11209 22457-22471 Protein denotes in IL-1RA mRNA
T11208 21751-21760 Protein denotes of IL-1RA
T11207 22189-22192 Entity denotes n =
T11206 21591-21597 Protein denotes IL-1RA
T11205 21826-21830 Protein denotes NFAT
T11204 21843-21849 Protein denotes NFIL-6
T11203 22790-22796 Protein denotes IL-1RA
T11202 22572-22578 Protein denotes IL-1RA
T11201 21662-21692 Entity denotes the transcription factor sites
T11200 22007-22018 Protein denotes IL-1RA mRNA
T11199 22633-22636 Entity denotes n =
T11198 22023-22029 Protein denotes IL-1RA
T11197 22307-22332 Protein denotes the highest IL-1RA amount
T10334 20630-20667 Regulation denotes of the IL-1 dependent release of IL-2
T10333 20002-20026 Gene_expression denotes in generating more IL-1β
T10332 20616-20703 Negative_regulation denotes by a decrease of the IL-1 dependent release of IL-2 from murine EL-4 cells following GP
T10331 19690-19700 Protein denotes IL-1β/IL-1
T10330 20673-20690 Entity denotes murine EL-4 cells
T10329 19978-19981 Entity denotes LPS
T10328 20027-20038 Protein denotes than IL-1RA
T10327 19841-19865 Entity denotes anti-inflammatory action
T10326 20457-20458 Entity denotes h
T10325 19675-19689 Protein denotes TSST-1-induced
T10324 19784-19790 Protein denotes IL-1RA
T10323 19893-19903 Protein denotes IL-1β/IL-1
T10322 20730-20736 Protein denotes TSST-1
T10321 20180-20190 Entity denotes IL-1β/IL-1
T10320 20304-20321 Protein denotes of GP/TSST-1 calc
T10319 20352-20395 Entity denotes a pronounced anti-inflammatory action of GP
T10318 19700-19702 Protein denotes RA
T10317 19690-19700 Protein denotes IL-1β/IL-1
T10316 20101-20104 Entity denotes LPS
T10315 20508-20517 Protein denotes of IL-1RA
T10314 20061-20094 Entity denotes i.e. up to 24 h. Comparing LPS vs
T10313 20016-20026 Protein denotes more IL-1β
T10312 19965-19968 Entity denotes LPS
T10311 20533-20536 Entity denotes n =
T10310 19893-19903 Protein denotes IL-1β/IL-1
T10309 20269-20278 Protein denotes to TSST-1
T10308 20637-20641 Protein denotes IL-1
T10307 20750-20754 Protein denotes calc
T10306 20466-20481 Entity denotes h of incubation
T10305 19774-19779 Protein denotes IL-1β
T10304 19899-19903 Protein denotes IL-1
T10303 20526-20531 Protein denotes IL-1β
T10302 20180-20190 Protein denotes IL-1β/IL-1
T10301 20176-20192 Protein denotes the IL-1β/IL-1RA
T10300 20332-20339 Protein denotes TSST-1,
T10299 20660-20667 Protein denotes of IL-2
T10298 20390-20395 Protein denotes of GP
T10297 20706-20712 Protein denotes TSST-1
T10296 20186-20190 Entity denotes IL-1
T10295 19903-19905 Protein denotes RA
T10294 20743-20749 Protein denotes TSST-1
T10293 19717-19737 Entity denotes an anti-inflammatory
T10292 20310-20316 Protein denotes TSST-1
T10291 19696-19700 Protein denotes IL-1
T9431 16440-16475 Positive_regulation denotes the activated transcription factors
T9430 16297-16328 Gene_expression denotes IL-1RA expression by human PBMC
T9429 16419-16518 Binding denotes we hypothesized that the activated transcription factors might bind to sites in the IL-1RA promoter true
T9428 17695-17764 Positive_regulation denotes showed an up-regulation of binding for all compounds and combinations
T9427 17968-17999 Binding denotes A new binding site for NFATP2/3
T9426 17850-17922 Positive_regulation denotes increased binding to the NFIL-6 site in comparison with TSST-1 (1.3fold)
T9425 16227-16262 Binding denotes NFAT binding in LPS-, TSST-1-, GP-,
T9424 17291-17297 Protein denotes TSST-1
T9423 17092-17102 Protein denotes the TSST-1
T9422 16503-16509 Protein denotes IL-1RA
T9421 16911-16941 Entity denotes A new κB3 site (-100 and -130)
T9420 17240-17242 Protein denotes GP
T9419 16997-17006 Protein denotes by TSST-1
T9418 16743-16783 Entity denotes site of LRE-1 (between -84 and -93) [30]
T9417 16620-16626 Protein denotes IL-1RA
T9416 16243-16262 Protein denotes LPS-, TSST-1-, GP-,
T9415 16282-16288 Protein denotes TSST-1
T9414 17060-17067 Entity denotes the LPS
T9413 18336-18342 Protein denotes TSST-1
T9412 17225-17228 Entity denotes LPS
T9411 17485-17496 Entity denotes LPS-induced
T9410 17939-17940 Entity denotes p
T9409 18301-18307 Protein denotes TSST-1
T9408 17272-17278 Entity denotes GP/LPS
T9407 16396-16403 Protein denotes no TNFα
T9406 18368-18371 Protein denotes Fig
T9405 16216-16222 Protein denotes NFIL-6
T9404 18358-18359 Entity denotes p
T9403 16413-16417 Protein denotes IFNγ
T9402 17423-17429 Protein denotes TSST-1
T9401 17230-17236 Protein denotes TSST-1
T9400 16487-16518 Entity denotes to sites in the IL-1RA promoter
T9399 17288-17302 Protein denotes GP/TSST-1 calc
T9398 16227-16231 Protein denotes NFAT
T9397 16363-16367 Protein denotes NFκB
T9396 18025-18077 Entity denotes the transcription start site, between -471 and -490,
T9395 16210-16214 Protein denotes NFκB
T9394 17269-17283 Protein denotes of GP/LPS calc
T9393 16277-16279 Protein denotes GP
T9392 16297-16303 Protein denotes IL-1RA
T9391 16369-16375 Protein denotes NFIL-6
T9390 18272-18291 Entity denotes LPS (1.4fold of GP)
T9389 17868-17886 Entity denotes to the NFIL-6 site
T9388 17832-17838 Protein denotes TSST-1
T9387 16698-16708 Protein denotes Oxford, UK
T9386 17431-17432 Entity denotes p
T9385 17275-17278 Entity denotes LPS
T9384 17968-17999 Entity denotes A new binding site for NFATP2/3
T9383 17272-17278 Protein denotes GP/LPS
T9382 16268-16272 Entity denotes LPS-
T9381 16499-16518 Entity denotes the IL-1RA promoter
T9380 16715-16718 Entity denotes LPS
T9379 17875-17881 Protein denotes NFIL-6
T9378 17644-17650 Protein denotes NFIL-6
T9377 17458-17466 Protein denotes The LPS-
T9376 18499-18503 Protein denotes calc
T9375 16249-16261 Protein denotes TSST-1-, GP-
T9374 16405-16409 Protein denotes IL-6
T9373 16249-16257 Protein denotes TSST-1-,
T9372 17906-17922 Protein denotes TSST-1 (1.3fold)
T9371 16616-16635 Entity denotes the IL-1RA promoter
T9370 16315-16328 Entity denotes by human PBMC
T9369 17358-17386 Entity denotes site (between -266 and -280)
T9368 16380-16384 Protein denotes NFAT
T9367 16440-16475 Protein denotes the activated transcription factors
T9366 17640-17671 Entity denotes The NFIL-6 site (-147 and -170)
T9365 18288-18290 Protein denotes GP
T9364 17505-17526 Entity denotes to the new κB2/3 site
T9363 17468-17475 Protein denotes TSST-1-
T7808 11701-11763 Gene_expression denotes no IL-1β production detectable following PBMC treatment with 1
T7807 14396-14417 Gene_expression denotes the IL-1RA production
T7806 11810-11829 Gene_expression denotes of IL-1β production
T7805 14450-14510 Positive_regulation denotes we found a synergistic increase in IL-1RA production from 18
T7804 13481-13521 Gene_expression denotes of the LPS-induced IL-6 production by GP
T7803 15142-15158 Gene_expression denotes TNFα production,
T7802 14482-14510 Gene_expression denotes in IL-1RA production from 18
T7801 15595-15613 Gene_expression denotes No IFNγ production
T7800 15287-15306 Gene_expression denotes the TNFα production
T7799 15954-16007 Gene_expression denotes The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1
T7798 15954-16007 Gene_expression denotes The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1
T7797 15954-16007 Gene_expression denotes The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1
T7796 15954-16007 Gene_expression denotes The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1
T7619 13844-13845 Entity denotes h
T7618 10782-10860 Protein denotes Cytokine profile of human PBMC following a 48 h in vitro stimulation with LPS,
T7617 14279-14280 Entity denotes h
T7616 15991-15996 Protein denotes IL-10
T7615 14337-14343 Entity denotes GP/LPS
T7614 11768-11777 Protein denotes 100 μg GP
T7613 13731-13735 Protein denotes IL-8
T7612 11413-11462 Entity denotes six additional transcription factor binding sites
T7611 15764-15767 Entity denotes LPS
T7610 14924-14930 Protein denotes IL-1RA
T7609 11083-11087 Protein denotes IL-8
T7608 15829-15841 Protein denotes TSST-1 at 24
T7607 15406-15408 Protein denotes GP
T7606 14519-14520 Entity denotes h
T7605 11095-11099 Protein denotes IFNγ
T7604 10956-10995 Entity denotes the TNFα, IL-8, IL-6 and IFNγ promoters
T7603 10878-10881 Entity denotes LPS
T7602 14650-14651 Entity denotes h
T7601 16181-16199 Entity denotes h (data not shown)
T7600 15449-15453 Protein denotes TNFα
T7599 15590-15594 Protein denotes IFNγ
T7598 11704-11709 Protein denotes IL-1β
T7597 15379-15385 Protein denotes TSST-1
T7596 11889-11895 Protein denotes TSST-1
T7595 14681-14682 Entity denotes h
T7594 14642-14649 Entity denotes h to 36
T7593 14340-14343 Entity denotes LPS
T7592 11946-11947 Entity denotes h
T7591 13613-13619 Protein denotes TSST-1
T7590 14865-14869 Entity denotes 24 h
T7589 15985-15989 Protein denotes IL-4
T7588 14915-14919 Protein denotes IL-8
T7587 11044-11048 Entity denotes PBMC
T7586 13589-13595 Protein denotes TSST-1
T7585 15072-15073 Entity denotes p
T7584 16160-16166 Protein denotes TSST-1
T7583 15649-15671 Entity denotes of PBMC with 100 μg GP
T7582 14614-14631 Protein denotes of GP/TSST-1 calc
T7581 11666-11670 Entity denotes LPS,
T7580 15044-15050 Protein denotes IL-1RA
T7579 13626-13632 Protein denotes TSST-1
T7578 14096-14102 Protein denotes TSST-1
T7577 15734-15743 Entity denotes LPS at 36
T7576 10802-10812 Entity denotes human PBMC
T7575 14143-14149 Protein denotes IL-1RA
T7574 14400-14406 Protein denotes IL-1RA
T7573 15065-15066 Entity denotes n
T7572 10886-10888 Protein denotes GP
T7571 13983-13987 Protein denotes calc
T7570 12033-12050 Protein denotes of GP/TSST-1 calc
T7569 13436-13440 Protein denotes IL-6
T7568 11089-11093 Protein denotes IL-6
T7567 10939-10995 Entity denotes seven sites from the TNFα, IL-8, IL-6 and IFNγ promoters
T7566 11500-11550 Protein denotes the following cytokine profile of human leukocytes
T7565 14814-14820 Protein denotes IL-1RA
T7564 15350-15353 Entity denotes LPS
T7563 13847-13848 Entity denotes n
T7562 11742-11756 Entity denotes PBMC treatment
T7561 15268-15271 Entity denotes LPS
T7560 15476-15479 Entity denotes n =
T7559 14485-14491 Protein denotes IL-1RA
T7558 16098-16113 Protein denotes LPS, TSST-1, GP
T7557 14511-14512 Entity denotes h
T7556 15851-15852 Entity denotes h
T7555 10960-10964 Protein denotes TNFα
T7554 11834-11836 Protein denotes GP
T7553 15061-15063 Protein denotes GP
T7552 10981-10985 Protein denotes IFNγ
T7551 16147-16153 Protein denotes TSST-1
T7550 13657-13722 Entity denotes h by about 40% (n = 5; both p = 0.02), (data not shown in detail)
T7549 15347-15358 Protein denotes GP/LPS calc
T7548 16098-16110 Entity denotes LPS, TSST-1,
T7547 13397-13401 Protein denotes IL-6
T7546 14164-14170 Protein denotes IL-1RA
T7545 15142-15146 Protein denotes TNFα
T7544 14794-14809 Protein denotes GP-induced IL-8
T7543 11369-11462 Protein denotes inflammatory cytokines over time (48 h) and six additional transcription factor binding sites
T7542 14443-14449 Protein denotes TSST-1
T7541 13883-13885 Protein denotes GP
T7540 15324-15327 Entity denotes LPS
T7539 13402-13412 Protein denotes GP induced
T7538 14700-14714 Protein denotes TSST-1-induced
T7537 14620-14626 Protein denotes TSST-1
T7536 15473-15474 Entity denotes h
T7535 16024-16029 Protein denotes by GP
T7534 15884-15890 Protein denotes TSST-1
T7533 14083-14089 Protein denotes TSST-1
T7532 13976-13982 Entity denotes GP/LPS
T7531 10966-10970 Protein denotes IL-8
T7530 11534-11550 Entity denotes human leukocytes
T7529 15662-15671 Protein denotes 100 μg GP
T7528 15291-15295 Protein denotes TNFα
T7527 15121-15125 Protein denotes TNFα
T7526 16157-16171 Protein denotes GP/TSST-1 calc
T7525 13500-13504 Protein denotes IL-6
T7524 15771-15777 Entity denotes GP/LPS
T7523 15392-15398 Protein denotes TSST-1
T7522 13564-13568 Protein denotes IL-6
T7521 14563-14567 Entity denotes 24 h
T7520 13855-13856 Entity denotes p
T7519 14722-14731 Protein denotes of IL-1RA
T7518 15703-15707 Protein denotes IFNγ
T7517 11685-11690 Protein denotes IL-1β
T7516 13516-13521 Protein denotes by GP
T7515 14536-14545 Protein denotes to TSST-1
T7514 15842-15843 Entity denotes h
T7513 13890-13893 Entity denotes LPS
T7512 13976-13982 Protein denotes GP/LPS
T7511 13775-13779 Protein denotes IL-8
T7510 11932-11945 Protein denotes IL-1β from 18
T7509 14563-14570 Entity denotes 24 h: n
T7508 13488-13499 Entity denotes LPS-induced
T7507 11403-11407 Entity denotes 48 h
T7506 14158-14162 Protein denotes IL-8
T7505 15744-15745 Entity denotes h
T761 507-513 Entity denotes glucan
T762 1584-1590 Entity denotes glucan
T763 1175-1181 Entity denotes Glucan
T764 977-1017 Entity denotes to a consensus site in the IL-8 promoter
T765 692-722 Protein denotes NFAT similar to LPS or TSST-1,
T766 1253-1257 Protein denotes NFAT
T767 715-721 Protein denotes TSST-1
T768 1584-1600 Entity denotes glucan phosphate
T769 1820-1826 Entity denotes glucan
T770 1757-1759 Protein denotes RA
T771 1893-1900 Protein denotes of IL-2
T772 911-918 Protein denotes of IL-8
T773 777-800 Protein denotes tumor necrosis factor α
T774 572-609 Protein denotes toxic shock syndrome toxin 1 (TSST-1)
T775 1703-1719 Entity denotes glucan phosphate
T776 69-155 Protein denotes IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio
T777 452-500 Entity denotes immune cells mediated by a fungal β-1→3-D-glucan
T778 602-608 Protein denotes TSST-1
T779 1104-1134 Entity denotes glucan phosphate-treated cells
T780 88-105 Entity denotes anti-inflammatory
T781 1460-1468 Protein denotes the LPS-
T782 1385-1391 Protein denotes TSST-1
T783 1247-1290 Entity denotes a new NFAT site within the IL-1RA promoter,
T784 1524-1528 Protein denotes NFAT
T785 1434-1440 Entity denotes glucan
T786 1000-1017 Entity denotes the IL-8 promoter
T787 1104-1110 Entity denotes glucan
T788 1669-1674 Protein denotes IL-1β
T789 804-844 Protein denotes interferon γ induced by glucan phosphate
T790 668-687 Protein denotes NFinterleukin(IL)-6
T791 2081-2117 Entity denotes an anti-inflammatory IL-1RA-mediated
T792 541-568 Entity denotes of lipopolysaccharide (LPS)
T793 1047-1061 Entity denotes antagonist(RA)
T794 1747-1757 Protein denotes IL-1β/IL-1
T795 1111-1128 Entity denotes phosphate-treated
T796 1867-1881 Protein denotes IL-1-dependent
T797 1774-1794 Entity denotes an anti-inflammatory
T798 846-852 Entity denotes Glucan
T799 1004-1008 Protein denotes IL-8
T800 708-711 Entity denotes LPS
T801 1378-1381 Entity denotes LPS
T802 1031-1072 Protein denotes in IL-1receptor antagonist(RA) production
T803 1732-1746 Protein denotes TSST-1-induced
T804 564-567 Entity denotes LPS
T805 1615-1629 Protein denotes TSST-1-induced
T806 1223-1242 Entity denotes a known NFIL-6 site
T807 2061-2117 Entity denotes switching a pro- to an anti-inflammatory IL-1RA-mediated
T808 2199-2205 Protein denotes IL-1RA
T809 1034-1038 Protein denotes IL-1
T810 1753-1757 Protein denotes IL-1
T811 1507-1511 Protein denotes NFκB
T812 804-844 Gene_expression denotes interferon γ induced by glucan phosphate
T813 804-844 Positive_regulation denotes interferon γ induced by glucan phosphate
T814 1806-1900 Negative_regulation denotes Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2
T2878 2922-2933 Entity denotes neutrophils
T2879 4136-4152 Entity denotes phosphoinositide
T2880 5654-5681 Entity denotes NFκB, PU.1 and NFIL-6 sites
T2881 5114-5118 Protein denotes IL-2
T2882 3524-3555 Protein denotes of the anti-inflammatory IL-1RA
T2883 4805-4811 Entity denotes glucan
T2884 5133-5138 Protein denotes IL-12
T2885 5143-5148 Protein denotes TGFβ1
T2886 3461-3472 Protein denotes IL-1, IL-6,
T2887 5508-5514 Protein denotes IL-1RA
T2888 5669-5675 Protein denotes NFIL-6
T2889 5308-5312 Protein denotes IFNγ
T2890 5172-5176 Protein denotes NFκB
T2891 5262-5284 Entity denotes the IL-8 promoter [28]
T2892 5627-5633 Protein denotes IL-1RA
T2893 5654-5658 Protein denotes NFκB
T2894 5061-5065 Protein denotes IL-6
T2895 4163-4167 Protein denotes PI3K
T2896 5501-5523 Entity denotes to the IL-1RA promoter
T2897 2818-2830 Entity denotes intact yeast
T2898 3150-3160 Entity denotes PGG-glucan
T2899 2689-2700 Entity denotes other cells
T2900 3350-3392 Entity denotes human polymorphonuclear neutrophils (PMN),
T2901 5120-5124 Protein denotes IL-4
T2902 3314-3392 Entity denotes monocyte-like cell line [15] and in human polymorphonuclear neutrophils (PMN),
T2903 4900-4923 Protein denotes the superantigen TSST-1
T2904 5350-5356 Protein denotes NFIL-6
T2905 2877-2884 Entity denotes zymosan
T2906 5238-5256 Entity denotes a κ consensus site
T2907 4865-4868 Entity denotes LPS
T2908 3387-3390 Entity denotes PMN
T2909 5167-5219 Entity denotes four NFκB sites from the TNFα promoter (κ consensus,
T2910 4805-4826 Entity denotes glucan phosphate (GP)
T2911 4747-4751 Entity denotes PBMC
T2912 2809-2812 Protein denotes PRR
T2913 3430-3478 Protein denotes of pro-inflammatory cytokines (IL-1, IL-6, TNFα)
T2914 4636-4656 Protein denotes the cytokine profile
T2915 3709-3725 Entity denotes human leukocytes
T2916 5286-5333 Entity denotes an NFAT site from the IFNγ promoter (ATP2) [29]
T2917 5476-5500 Protein denotes of transcription factors
T2918 2655-2706 Protein denotes receptors on phagocytes [3,4] and other cells [5,6]
T2919 5108-5112 Protein denotes IFNγ
T2920 3730-3762 Entity denotes human vascular endothelial cells
T2921 5367-5389 Entity denotes the IL-6 promoter [13]
T2922 5413-5453 Entity denotes of the anti-inflammatory role of IL-1RA,
T2923 5048-5052 Protein denotes TNFα
T2924 3100-3110 Protein denotes MyD88 [12]
T2925 3150-3160 Entity denotes PGG-glucan
T2926 3025-3046 Gene_expression denotes in production of TNFα
T2927 5454-5523 Binding denotes we focused on binding of transcription factors to the IL-1RA promoter
T2928 3509-3569 Gene_expression denotes the production of the anti-inflammatory IL-1RA, but not IL-1
T2929 3181-3208 Positive_regulation denotes to activate NFκB and NFIL-6
T2930 3181-3208 Positive_regulation denotes to activate NFκB and NFIL-6
T2931 2655-2706 Localization denotes receptors on phagocytes [3,4] and other cells [5,6]
T2932 3420-3478 Gene_expression denotes secretion of pro-inflammatory cytokines (IL-1, IL-6, TNFα)
T2933 3704-3803 Gene_expression denotes that human leukocytes and human vascular endothelial cells produce IL-8 in response to zymosan [18]
T4206 5922-5926 Protein denotes IL-6
T4207 6684-6692 Protein denotes NFκB p65
T4208 5922-5995 Entity denotes IL-6 and IFNγ promoters following an in vitro stimulation (1 h) with LPS,
T4209 5996-6010 Protein denotes TSST-1, GP, GP
T4210 6098-6160 Protein denotes NFIL-6 to the corresponding DNA oligonucleotides (κ consensus,
T4211 6934-6948 Protein denotes TSST-1-induced
T4212 6539-6547 Protein denotes NFκB p65
T4213 5898-5920 Entity denotes human PBMC to the TNFα
T4214 6223-6227 Protein denotes IL-8
T4215 6684-6688 Protein denotes NFκB
T4216 6108-6160 Entity denotes the corresponding DNA oligonucleotides (κ consensus,
T4217 6715-6721 Protein denotes of p50
T4218 5912-5920 Protein denotes the TNFα
T4219 6892-6895 Protein denotes Fig
T4220 6187-6191 Protein denotes TNFα
T4221 6979-6985 Protein denotes TSST-1
T4222 6471-6489 Entity denotes the IL-8 promoter,
T4223 7063-7069 Protein denotes TSST-1
T4224 5888-5892 Protein denotes NFAT
T4225 6797-6799 Protein denotes GP
T4226 7261-7265 Protein denotes IFNγ
T4227 7100-7106 Protein denotes TSST-1
T4228 6238-6242 Protein denotes NFIL
T4229 5981-5984 Entity denotes 1 h
T4230 5991-5995 Entity denotes LPS,
T4231 6219-6276 Entity denotes the IL-8 promoter; NFIL-6consensus from the IL-6 promoter
T4232 6859-6876 Entity denotes the TNFα promoter
T4233 6819-6830 Entity denotes LPS-induced
T4234 6475-6479 Protein denotes IL-8
T4235 6641-6656 Entity denotes GP-treated PBMC
T4236 7232-7239 Protein denotes of NFAT
T4237 6461-6465 Entity denotes site
T4238 6183-6200 Entity denotes the TNFα promoter
T4239 5996-6007 Protein denotes TSST-1, GP,
T4240 7057-7074 Protein denotes of GP/TSST-1 calc
T4241 6619-6656 Entity denotes nuclear extracts from GP-treated PBMC
T4242 7257-7284 Entity denotes the IFNγ promoter (Fig. 1A)
T4243 6446-6450 Protein denotes NFκB
T4244 6026-6032 Protein denotes TSST-1
T4245 7097-7111 Protein denotes GP/TSST-1 calc
T4246 6263-6267 Protein denotes IL-6
T4247 6390-6393 Entity denotes LPS
T4248 6076-6083 Protein denotes of NFκB
T4249 6574-6587 Protein denotes p50 (Fig. 1A)
T4250 7392-7398 Protein denotes NFATc1
T4251 6731-6734 Protein denotes p52
T4252 6784-6799 Entity denotes of PBMC with GP
T4253 5871-5875 Protein denotes NFκB
T4254 6126-6129 Entity denotes DNA
T4255 6169-6200 Entity denotes κ3 sites from the TNFα promoter
T4256 7308-7312 Protein denotes NFAT
T4257 5931-5935 Protein denotes IFNγ
T4258 5877-5883 Protein denotes NFIL-6
T4259 6539-6543 Protein denotes NFκB
T4260 6397-6403 Protein denotes TSST-1
T4261 7359-7365 Protein denotes NFATc2
T4262 6021-6023 Protein denotes GP
T4263 6013-6016 Entity denotes LPS
T4264 6863-6867 Protein denotes TNFα
T4265 6259-6276 Entity denotes the IL-6 promoter
T4266 7130-7145 Protein denotes TSST-1; Fig. 1B
T26179 7431-7450 Entity denotes of oligonucleotides
T26286 28006-28051 Entity denotes regulatory transcription factor binding sites
T26285 27863-27885 Entity denotes of the IL-1RA promoter
T26284 27870-27876 Protein denotes IL-1RA
T729 1513-1519 Protein denotes NFIL-6
T730 846-881 Entity denotes Glucan phosphate-treated leukocytes
T731 771-775 Protein denotes IL-6
T732 1567-1573 Protein denotes IL-1RA
T733 1851-1865 Protein denotes TSST-1-induced
T734 1703-1709 Entity denotes glucan
T735 1058-1060 Protein denotes RA
T736 1270-1290 Entity denotes the IL-1RA promoter,
T737 1747-1757 Protein denotes IL-1β/IL-1
T738 1231-1237 Protein denotes NFIL-6
T739 764-769 Protein denotes IL-1β
T740 507-609 Entity denotes glucan phosphate, in the presence of lipopolysaccharide (LPS) or toxic shock syndrome toxin 1 (TSST-1)
T741 119-129 Protein denotes IL-1β/IL-1
T742 139-149 Entity denotes antagonist
T743 853-870 Entity denotes phosphate-treated
T744 1085-1086 Entity denotes h
T745 130-138 Protein denotes receptor
T746 2192-2211 Protein denotes of the IL-1RA gene,
T747 1274-1280 Protein denotes IL-1RA
T748 1820-1836 Entity denotes glucan phosphate
T749 825-844 Entity denotes by glucan phosphate
T750 931-932 Entity denotes h
T751 1477-1491 Protein denotes TSST-1-induced
T752 1162-1166 Protein denotes IL-8
T753 828-834 Entity denotes glucan
T754 969-976 Protein denotes of NFκB
T755 1679-1683 Protein denotes IL-6
T756 125-129 Protein denotes IL-1
T757 2027-2035 Protein denotes receptor
T817 723-844 Gene_expression denotes we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate
T758 1429-1450 Entity denotes that glucan phosphate
T759 1175-1199 Entity denotes Glucan phosphate induced
T760 119-129 Protein denotes IL-1β/IL-1
T815 1847-1900 Regulation denotes the TSST-1-induced, IL-1-dependent production of IL-2
T816 723-844 Gene_expression denotes we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate
T818 723-844 Gene_expression denotes we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate
T819 723-844 Gene_expression denotes we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate
T820 2027-2043 Binding denotes receptor binding
T821 1019-1072 Positive_regulation denotes An increase in IL-1receptor antagonist(RA) production
T822 961-1017 Binding denotes binding of NFκB to a consensus site in the IL-8 promoter
T823 1847-1900 Gene_expression denotes the TSST-1-induced, IL-1-dependent production of IL-2
T2836 5054-5059 Protein denotes IL-1β
T2837 4563-4579 Entity denotes human leukocytes
T2838 4711-4752 Entity denotes peripheral blood mononuclear cells (PBMC)
T2839 4960-4961 Entity denotes h
T2840 5338-5361 Entity denotes a consensus NFIL-6 site
T2841 2668-2684 Entity denotes phagocytes [3,4]
T2842 5188-5219 Entity denotes the TNFα promoter (κ consensus,
T2843 3461-3477 Protein denotes IL-1, IL-6, TNFα
T2844 5266-5270 Protein denotes IL-8
T2845 5304-5328 Entity denotes the IFNγ promoter (ATP2)
T2846 3467-3471 Protein denotes IL-6
T2847 5573-5576 Entity denotes LPS
T2848 3007-3015 Protein denotes Dectin-1
T2849 5067-5071 Protein denotes IL-8
T2850 3524-3555 Entity denotes of the anti-inflammatory IL-1RA
T2851 3298-3302 Protein denotes NFκB
T2852 5623-5682 Entity denotes the IL-1RA promoter, including NFκB, PU.1 and NFIL-6 sites,
T2853 3791-3803 Entity denotes zymosan [18]
T2854 5192-5196 Protein denotes TNFα
T2855 3193-3197 Protein denotes NFκB
T2856 3565-3569 Protein denotes IL-1
T2857 2725-2740 Protein denotes murine Dectin-1
T2858 2835-2870 Entity denotes β-1→3-D-glucan-containing particles
T2859 4904-4916 Protein denotes superantigen
T2860 5126-5131 Protein denotes IL-10
T2861 2315-2338 Entity denotes of microbial cell walls
T2862 3039-3046 Protein denotes of TNFα
T2863 3573-3588 Entity denotes human monocytes
T2864 5818-5837 Entity denotes the IL-1RA promoter
T2865 5660-5664 Protein denotes PU.1
T2866 5076-5082 Protein denotes IL-1RA
T2867 5822-5828 Protein denotes IL-1RA
T2868 2769-2813 Protein denotes the major pattern recognition receptor (PRR)
T2869 4155-4161 Protein denotes kinase
T2870 3202-3208 Protein denotes NFIL-6
T2871 2886-2961 Entity denotes on monocytes/macrophages as well as neutrophils and on primary cells [7-11]
T2872 4108-4112 Protein denotes NFκB
T2873 2554-2558 Protein denotes PAMP
T2874 5371-5375 Protein denotes IL-6
T2875 5443-5452 Protein denotes of IL-1RA
T2876 3771-3775 Protein denotes IL-8
T2877 3055-3075 Protein denotes Toll-like receptor 2
T7644 11813-11818 Protein denotes IL-1β
T7643 15881-15895 Protein denotes GP/TSST-1 calc
T7642 12121-12135 Protein denotes TSST-1-induced
T7641 12166-12169 Protein denotes Fig
T7640 15922-15953 Protein denotes IL-2, IL-12, IL-4, IL-10, TGFβ1
T7639 13979-13982 Entity denotes LPS
T7638 14337-14343 Protein denotes GP/LPS
T7637 11227-11255 Entity denotes of human blood cells [15-18]
T7636 14861-14871 Protein denotes GP (24 h),
T7635 11077-11081 Protein denotes TNFα
T7634 15347-15353 Protein denotes GP/LPS
T7633 14282-14285 Entity denotes n =
T7632 16120-16136 Protein denotes LPS, GP/LPS calc
T7631 10861-10872 Protein denotes TSST-1, GP,
T7630 16001-16007 Protein denotes TGFβ 1
T7629 13969-13972 Entity denotes LPS
T7628 14755-14758 Protein denotes Fig
T7627 15928-15940 Protein denotes IL-12, IL-4,
T7626 11666-11677 Protein denotes LPS, TSST-1
T7625 15598-15602 Protein denotes IFNγ
T7624 10861-10875 Protein denotes TSST-1, GP, GP
T7623 11208-11216 Protein denotes cytokine
T7622 15774-15777 Entity denotes LPS
T7621 15922-15947 Protein denotes IL-2, IL-12, IL-4, IL-10,
T7620 15978-15983 Protein denotes IL-12
T16949 31060-31131 Regulation denotes the TSST-1-induced, IL-1-dependent IL-2 production of murine EL-4 cells
T16948 25092-25113 Transcription denotes of IL-8 transcription
T7795 15954-16007 Gene_expression denotes The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1
T7794 13761-13791 Gene_expression denotes a substantial IL-8 production,
T7793 13903-13951 Positive_regulation denotes in a non-significant increase of IL-8 production
T7792 11779-11836 Positive_regulation denotes An insignificant up-regulation of IL-1β production for GP
T7791 13933-13951 Gene_expression denotes of IL-8 production
T7790 15703-15731 Gene_expression denotes IFNγ production following GP
T7789 13455-13521 Regulation denotes no significant alteration of the LPS-induced IL-6 production by GP
T7788 13552-13586 Negative_regulation denotes a decreased IL-6 production for GP
T7787 13523-13586 Gene_expression denotes On the contrary, we observed a decreased IL-6 production for GP
T7786 11193-11255 Negative_regulation denotes only a limited cytokine secretion of human blood cells [15-18]
T7785 15446-15472 Gene_expression denotes on TNFα secretion after 36
T7784 14028-14056 Gene_expression denotes IL-8 production following GP
T7783 14318-14321 Entity denotes LPS
T7782 15347-15353 Entity denotes GP/LPS
T7781 15972-15976 Protein denotes IL-2
T7780 15928-15946 Protein denotes IL-12, IL-4, IL-10
T7779 12039-12045 Protein denotes TSST-1
T7778 10972-10976 Protein denotes IL-6
T7777 16120-16136 Entity denotes LPS, GP/LPS calc
T7776 10856-10859 Entity denotes LPS
T7775 13936-13940 Protein denotes IL-8
T7774 14080-14107 Protein denotes to TSST-1 or GP/TSST-1 calc
T7773 16103-16109 Protein denotes TSST-1
T7772 11839-11842 Entity denotes LPS
T7771 15935-15939 Protein denotes IL-4
T7770 10891-10897 Protein denotes TSST-1
T7769 16120-16124 Entity denotes LPS,
T7768 12143-12151 Protein denotes of IL-1β
T7767 14059-14065 Protein denotes TSST-1
T7766 12001-12007 Protein denotes TSST-1
T7765 14028-14032 Protein denotes IL-8
T7764 15871-15877 Protein denotes TSST-1
T7763 11875-11878 Entity denotes LPS
T7762 15035-15039 Protein denotes IL-8
T7761 15771-15777 Protein denotes GP/LPS
T7760 14356-14359 Entity denotes LPS
T16947 25959-25990 Binding denotes four new binding sites (Fig. 8)
T17446 32254-32260 Entity denotes glucan
T17445 32940-32950 Protein denotes IL-1β/IL-1
T17444 32857-32876 Entity denotes by glucan phosphate
T17443 32940-32950 Protein denotes IL-1β/IL-1
T17442 32254-32270 Entity denotes glucan phosphate
T17441 32950-32952 Protein denotes RA
T17440 32427-32441 Protein denotes TSST-1-induced
T17439 32457-32472 Protein denotes IL-1RA-mediated
T17438 32650-32678 Entity denotes the IL-1RA promoter (Fig. 8)
T17437 32314-32335 Protein denotes a subsequent cytokine
T17436 32860-32866 Entity denotes glucan
T17435 32359-32362 Entity denotes LPS
T16970 30500-30569 Positive_regulation denotes the synergistic up-regulation of the TSST-1-induced IL-1RA production
T16969 26190-26213 Gene_expression denotes to production of IL-1RA
T16968 27570-27594 Positive_regulation denotes kinase signaling [44,45]
T16967 26482-26528 Binding denotes NFIL-6 binding to sites in the IL-1RA promoter
T16966 26922-26987 Gene_expression denotes to produce IL-8 just as IL-1RA in response to GP (data not shown)
T16965 24618-24650 Negative_regulation denotes a very limited cytokine response
T16964 31677-31718 Positive_regulation denotes in the activation of NFAT in T cells [49]
T16963 31548-31623 Regulation denotes the PI3K pathway selectively controls sIL-1RA but not IL-1β production [48]
T16962 28523-28546 Positive_regulation denotes up-regulation of IL-1RA
T16961 31463-31483 Regulation denotes GP treatment [22,37]
T16960 31988-32085 Positive_regulation denotes LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins
T16959 31988-32085 Positive_regulation denotes LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins
T16958 25822-25849 Positive_regulation denotes it strongly induced IL-1RA,
T16957 25822-25849 Gene_expression denotes it strongly induced IL-1RA,
T16956 26759-26833 Gene_expression denotes monocytes as well as neutrophils have been reported to produce IL-1RA [32]
T16955 28447-28481 Negative_regulation denotes down-regulation of IL-1β and IL-6,
T16954 28447-28481 Negative_regulation denotes down-regulation of IL-1β and IL-6,
T16953 25269-25301 Transcription denotes A GP-mediated IL-8 transcription
T16952 26691-26714 Positive_regulation denotes for induction of IL-1RA
T16951 26691-26714 Gene_expression denotes for induction of IL-1RA
T16950 24797-24814 Gene_expression denotes IL-1RA production
T16946 27453-27472 Localization denotes the T cell receptor
T16945 24383-24406 Binding denotes NFAT binding (Fig. 1A),
T16944 31602-31623 Gene_expression denotes IL-1β production [48]
T16943 28941-28977 Gene_expression denotes the TSST-1-induced IL-1RA production
T16942 31862-31896 Positive_regulation denotes mitogen-activated kinase signaling
R7419 T11216 T11234 themeOf of NFκB,"an inhibition of NFκB via CAPE [35] and CyA,"
R7420 T11228 T11217 partOf the IL-1RA promoter,IL-1RA
R7421 T11231 T11232 themeOf the NFκB and NFIL-6 binding sites,the NFκB and NFIL-6 binding sites
R11414 T16699 T16917 partOf of the TNFα promoter,TNFα
R11422 T16714 T16938 themeOf NFAT-mers,"binding of NFκB-, NFIL-6- and NFAT-mers"
R11426 T16728 T16782 partOf of the IL-8 promoter,IL-8
R11433 T16738 T16696 partOf cytokine promoters,cytokine promoters
R11449 T16762 T16724 partOf the IL-1RA promoter,IL-1RA
R11454 T16767 T16903 partOf to sites from the TNFα promoter,of NFκB
R11458 T16770 T16851 partOf the TNFα promoter,TNFα
R11461 T16783 T16753 partOf "the IL-1RA promoter,",IL-1RA
R11464 T16788 T16938 themeOf NFIL-6,"binding of NFκB-, NFIL-6- and NFAT-mers"
R11465 T16792 T16934 themeOf IL-1β,that GP did not induce IL-1β
R11466 T16792 T16935 themeOf IL-1β,that GP did not induce IL-1β
R11471 T16801 T16921 partOf of the IL-1RA promoter,IL-1RA
R11474 T16803 T16939 themeOf the TSST-1,"Accordingly, we found that the TSST-1-induced binding of NFκB to sites from the TNFα promoter"
R11479 T16814 T16938 themeOf NFκB-,"binding of NFκB-, NFIL-6- and NFAT-mers"
R11481 T16820 T16825 partOf the IL-1RA promoter,IL-1RA
R11482 T16852 T16874 partOf IL-1RA promoter,IL-1RA
R11484 T16865 T16935 causeOf that GP,that GP did not induce IL-1β
R11485 T16839 T16818 partOf the IL-1RA promoter [34],IL-1RA
R11486 T16876 T16932 themeOf IL-8,the GP-mediated IL-8 transcription
R11491 T16899 T16937 themeOf to MHC-II molecules,binding to MHC-II molecules
R11493 T16903 T16939 themeOf of NFκB,"Accordingly, we found that the TSST-1-induced binding of NFκB to sites from the TNFα promoter"
R11494 T16904 T16933 themeOf conserved nucleotides,conserved nucleotides
R11495 T16919 T16897 partOf the IL-1RA promoter [30],IL-1RA
R12857 T18743 T18754 themeOf of NFAT and NFκB proteins,for the binding of NFAT and NFκB proteins
R12858 T18749 T18740 partOf the IFNγ promoter [29],IFNγ
R12859 T18750 T18745 partOf of the TNFα promoter [55],TNFα
R12860 T18754 T18755 themeOf for the binding of NFAT and NFκB proteins,"which seem to be crucial for the binding of NFAT and NFκB proteins, respectively"
R13180 T19147 T19160 themeOf non-specific binding to nuclear proteins,non-specific binding to nuclear proteins
R13181 T19152 T19159 themeOf promoter,the cytokine promoter binding
R13182 T19155 T19160 themeOf to nuclear proteins,non-specific binding to nuclear proteins
R13880 T20198 T20205 themeOf cytokine,donors showing no spontaneous cytokine release
R14420 T20909 T20898 partOf the IL-1RA promoter,IL-1RA
R14421 T20913 T20944 themeOf messenger RNA,messenger RNA was transcribed
R14422 T20913 T20945 themeOf messenger RNA,messenger RNA was transcribed
R14423 T20917 T20921 partOf "the IL-1RA promoter,",IL-1RA
R14424 T20925 T20943 locationOf PBMC,PBMC RNA
R14425 T20931 T20943 themeOf PBMC RNA,PBMC RNA
R14426 T20933 T20942 themeOf of transcription factors,Inhibition of transcription factors
R14427 T20934 T20946 themeOf of transcription factors,"binding of transcription factors to the IL-1RA promoter,"
R15304 T22245 T22254 partOf "to the IFNγ, TNFα, IL-6 and IL-8 gene promoters","IFNγ, TNFα,"
R15596 T22799 T22816 themeOf the DNA binding proteins,the DNA binding proteins activated
R16230 T23765 T23793 themeOf IL-1RA,IL-1RA production (pg/ml)
R16231 T23767 T23795 themeOf IL-1β,IL-1β production following GP
R16232 T23775 T23796 themeOf IL-1RA,a higher IL-1RA production
R16233 T23784 T23794 themeOf IL-1β,IL-1β production (pg/ml)
R16444 T24116 T24121 partOf the IL-1RA promoter,IL-1RA
R16852 T24683 T24689 partOf the IL-1RA promoter,IL-1RA
R16853 T24686 T24699 partOf the IL-1RA promoter,IL-1RA
R17227 T25345 T25391 themeOf more IL-1β,in generating more IL-1β
R17803 T26111 T26133 themeOf of IL-1RA,the production of IL-1RA
R17804 T26114 T26131 themeOf "NFκB, NFAT and NFIL-6 DNA","NFκB, NFAT and NFIL-6 DNA binding to the IL-1RA promoter"
R17805 T26119 T26132 themeOf of NFκB,Inhibition of NFκB
R17806 T26124 T26126 partOf to the IL-1RA promoter,IL-1RA
R17807 T26124 T26131 themeOf to the IL-1RA promoter,"NFκB, NFAT and NFIL-6 DNA binding to the IL-1RA promoter"
R17808 T26133 T26135 themeOf the production of IL-1RA,"C, Inhibition of NFκB, NFAT and NFIL-6 significantly reduced the production of IL-1RA"
R17922 T26285 T26284 partOf of the IL-1RA promoter,IL-1RA
R1834 T2913 T2932 themeOf "of pro-inflammatory cytokines (IL-1, IL-6, TNFα)","secretion of pro-inflammatory cytokines (IL-1, IL-6, TNFα)"
R1839 T2917 T2927 themeOf of transcription factors,we focused on binding of transcription factors to the IL-1RA promoter
R1840 T2918 T2931 themeOf "receptors on phagocytes [3,4] and other cells [5,6]","receptors on phagocytes [3,4] and other cells [5,6]"
R1841 T2921 T2874 partOf the IL-6 promoter [13],IL-6
R2698 T4265 T4246 partOf the IL-6 promoter,IL-6
R2712 T4222 T4234 partOf "the IL-8 promoter,",IL-8
R2713 T4232 T4264 partOf the TNFα promoter,TNFα
R2714 T4238 T4220 partOf the TNFα promoter,TNFα
R2715 T4242 T4226 partOf the IFNγ promoter (Fig. 1A),IFNγ
R4942 T7511 T7794 themeOf IL-8,"a substantial IL-8 production,"
R4948 T7518 T7790 themeOf IFNγ,IFNγ production following GP
R4950 T7522 T7787 themeOf IL-6,"On the contrary, we observed a decreased IL-6 production for GP"
R4952 T7525 T7804 themeOf IL-6,of the LPS-induced IL-6 production by GP
R4954 T7528 T7800 themeOf TNFα,the TNFα production
R4962 T7545 T7803 themeOf TNFα,"TNFα production,"
R4969 T7559 T7802 themeOf IL-1RA,in IL-1RA production from 18
R4976 T7574 T7807 themeOf IL-1RA,the IL-1RA production
R4978 T7620 T7798 themeOf IL-12,"The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1"
R4979 T7625 T7801 themeOf IFNγ,No IFNγ production
R4980 T7630 T7797 themeOf TGFβ 1,"The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1"
R4981 T7589 T7795 themeOf IL-4,"The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1"
R4982 T7644 T7806 themeOf IL-1β,of IL-1β production
R4983 T7598 T7808 themeOf IL-1β,no IL-1β production detectable following PBMC treatment with 1
R4984 T7600 T7785 themeOf TNFα,on TNFα secretion after 36
R4986 T7616 T7799 themeOf IL-10,"The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1"
R5049 T7806 T7792 themeOf of IL-1β production,An insignificant up-regulation of IL-1β production for GP
R5050 T7765 T7784 themeOf IL-8,IL-8 production following GP
R5051 T7775 T7791 themeOf IL-8,of IL-8 production
R5052 T7781 T7796 themeOf IL-2,"The production of IL-2, IL-12, IL-4, IL-10 and TGFβ 1"
R5053 T7787 T7788 themeOf "On the contrary, we observed a decreased IL-6 production for GP",a decreased IL-6 production for GP
R5054 T7791 T7793 themeOf of IL-8 production,in a non-significant increase of IL-8 production
R5055 T7802 T7805 themeOf in IL-1RA production from 18,we found a synergistic increase in IL-1RA production from 18
R5056 T7804 T7789 themeOf of the LPS-induced IL-6 production by GP,no significant alteration of the LPS-induced IL-6 production by GP
R6246 T9367 T9431 themeOf the activated transcription factors,the activated transcription factors
R6247 T9371 T9417 partOf the IL-1RA promoter,IL-1RA
R6248 T9381 T9422 partOf the IL-1RA promoter,IL-1RA
R6249 T9384 T9427 themeOf A new binding site for NFATP2/3,A new binding site for NFATP2/3
R6250 T9392 T9430 themeOf IL-1RA,IL-1RA expression by human PBMC
R6251 T9398 T9425 themeOf NFAT,"NFAT binding in LPS-, TSST-1-, GP-,"
R6801 T10299 T10334 themeOf of IL-2,of the IL-1 dependent release of IL-2
R6802 T10308 T10334 causeOf IL-1,of the IL-1 dependent release of IL-2
R6803 T10313 T10333 themeOf more IL-1β,in generating more IL-1β
R6804 T10334 T10332 themeOf of the IL-1 dependent release of IL-2,by a decrease of the IL-1 dependent release of IL-2 from murine EL-4 cells following GP
R197 T771 T823 themeOf of IL-2,"the TSST-1-induced, IL-1-dependent production of IL-2"
R198 T773 T819 themeOf tumor necrosis factor α,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate"
R199 T786 T799 partOf the IL-8 promoter,IL-8
R200 T789 T812 themeOf interferon γ induced by glucan phosphate,interferon γ induced by glucan phosphate
R201 T789 T813 themeOf interferon γ induced by glucan phosphate,interferon γ induced by glucan phosphate
R202 T789 T818 themeOf interferon γ induced by glucan phosphate,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate"
R203 T796 T815 causeOf IL-1-dependent,"the TSST-1-induced, IL-1-dependent production of IL-2"
R328 T731 T816 themeOf IL-6,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate"
R329 T736 T747 partOf "the IL-1RA promoter,",IL-1RA
R330 T739 T817 themeOf IL-1β,"we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate"
R331 T748 T814 causeOf glucan phosphate,"Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2"
R332 T749 T813 causeOf by glucan phosphate,interferon γ induced by glucan phosphate
R333 T754 T822 themeOf of NFκB,binding of NFκB to a consensus site in the IL-8 promoter
R334 T757 T820 themeOf receptor,receptor binding
R335 T823 T814 themeOf "the TSST-1-induced, IL-1-dependent production of IL-2","Subsequently, glucan phosphate decreased the TSST-1-induced, IL-1-dependent production of IL-2"
R336 T823 T815 themeOf "the TSST-1-induced, IL-1-dependent production of IL-2","the TSST-1-induced, IL-1-dependent production of IL-2"
R1788 T2841 T2931 locationOf "phagocytes [3,4]","receptors on phagocytes [3,4] and other cells [5,6]"
R1798 T2842 T2854 partOf "the TNFα promoter (κ consensus,",TNFα
R1802 T2845 T2889 partOf the IFNγ promoter (ATP2),IFNγ
R1805 T2852 T2892 partOf "the IL-1RA promoter, including NFκB, PU.1 and NFIL-6 sites,",IL-1RA
R1809 T2855 T2929 themeOf NFκB,to activate NFκB and NFIL-6
R1810 T2862 T2926 themeOf of TNFα,in production of TNFα
R1811 T2864 T2867 partOf the IL-1RA promoter,IL-1RA
R1816 T2870 T2930 themeOf NFIL-6,to activate NFκB and NFIL-6
R1817 T2876 T2933 themeOf IL-8,that human leukocytes and human vascular endothelial cells produce IL-8 in response to zymosan [18]
R1818 T2882 T2928 themeOf of the anti-inflammatory IL-1RA,"the production of the anti-inflammatory IL-1RA, but not IL-1"
R1829 T2891 T2844 partOf the IL-8 promoter [28],IL-8
R1830 T2896 T2887 partOf to the IL-1RA promoter,IL-1RA
R1831 T2896 T2927 themeOf to the IL-1RA promoter,we focused on binding of transcription factors to the IL-1RA promoter
R1832 T2899 T2931 locationOf other cells,"receptors on phagocytes [3,4] and other cells [5,6]"
R11408 T16688 T16967 themeOf NFIL-6 binding to sites in the IL-1RA promoter,NFIL-6 binding to sites in the IL-1RA promoter
R11410 T16691 T16945 themeOf NFAT,"NFAT binding (Fig. 1A),"
R11411 T16694 T16964 themeOf of NFAT,in the activation of NFAT in T cells [49]
R11415 T16700 T16959 themeOf the IL-1RA gene,LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins
R11416 T16700 T16960 themeOf the IL-1RA gene,LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins
R11417 T16703 T16959 causeOf peptidoglycan,LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins
R11421 T16713 T16949 causeOf IL-1-dependent,"the TSST-1-induced, IL-1-dependent IL-2 production of murine EL-4 cells"
R11427 T16730 T16969 themeOf of IL-1RA,to production of IL-1RA
R11431 T16736 T16968 causeOf kinase,"kinase signaling [44,45]"
R11434 T16740 T16956 themeOf IL-1RA [32],monocytes as well as neutrophils have been reported to produce IL-1RA [32]
R11437 T16745 T16951 themeOf of IL-1RA,for induction of IL-1RA
R11438 T16745 T16952 themeOf of IL-1RA,for induction of IL-1RA
R11439 T16746 T16963 themeOf sIL-1RA,the PI3K pathway selectively controls sIL-1RA but not IL-1β production [48]
R11443 T16756 T16947 themeOf four new binding sites (Fig. 8),four new binding sites (Fig. 8)
R11452 T16764 T16960 causeOf LPS,LPS and peptidoglycan activated the IL-1RA gene through different mechanisms/DNA-binding proteins
R11455 T16767 T16939 siteOf to sites from the TNFα promoter,"Accordingly, we found that the TSST-1-induced binding of NFκB to sites from the TNFα promoter"
R11460 T16779 T16944 themeOf IL-1β,IL-1β production [48]
R11467 T16793 T16946 themeOf the T cell receptor,the T cell receptor
R11468 T16797 T16950 themeOf IL-1RA,IL-1RA production
R11469 T16799 T16942 causeOf kinase,mitogen-activated kinase signaling
R11473 T16802 T16948 themeOf IL-8,of IL-8 transcription
R11475 T16806 T16940 themeOf "NFIL-6 [13,39] or NFATc2 dimer binding to the IL-8κB site [38]","NFIL-6 [13,39] or NFATc2 dimer binding to the IL-8κB site [38]"
R11476 T16807 T16955 themeOf IL-6,"down-regulation of IL-1β and IL-6,"
R11478 T16850 T16943 themeOf IL-1RA,the TSST-1-induced IL-1RA production
R11480 T16817 T16961 themeOf GP,"GP treatment [22,37]"
R11483 T16853 T16966 themeOf IL-8,to produce IL-8 just as IL-1RA in response to GP (data not shown)
R11487 T16877 T16954 themeOf IL-1β,"down-regulation of IL-1β and IL-6,"
R11488 T16879 T16957 themeOf "IL-1RA,","it strongly induced IL-1RA,"
R11489 T16879 T16958 themeOf "IL-1RA,","it strongly induced IL-1RA,"
R11490 T16882 T16953 themeOf IL-8,A GP-mediated IL-8 transcription
R11492 T16902 T16941 themeOf IL-1RA,of the TSST-1-induced IL-1RA production
R11496 T16923 T16962 themeOf of IL-1RA,up-regulation of IL-1RA
R11497 T16924 T16946 locationOf T cell,the T cell receptor
R11498 T16929 T16965 themeOf a very limited cytokine response,a very limited cytokine response
R11499 T16941 T16970 themeOf of the TSST-1-induced IL-1RA production,the synergistic up-regulation of the TSST-1-induced IL-1RA production
R11764 T17438 T17450 partOf the IL-1RA promoter (Fig. 8),IL-1RA

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T26248 27885-27886 . denotes .
T26247 27877-27885 NN denotes promoter
T26246 27870-27876 NN denotes IL-1RA
T26245 27866-27869 DT denotes the
T26244 27863-27865 IN denotes of
T26243 27856-27862 NN denotes strand
T26242 27850-27855 NN denotes sense
T26241 27846-27849 DT denotes the
T26240 27843-27845 IN denotes of
T26239 27835-27842 NNP denotes Cartoon
T26048 23658-23659 -LRB- denotes (
T26047 23655-23657 NNP denotes GP
T26046 23652-23654 TO denotes to
T26045 23643-23651 VBN denotes compared
T26044 23638-23642 WRB denotes when
T26043 23634-23637 NNP denotes CyA
T26042 23631-23633 CC denotes or
T26041 23626-23630 NNP denotes CAPE
T26040 23624-23625 , denotes ,
T26039 23621-23624 NNP denotes CHX
T26038 23616-23620 IN denotes with
T26037 23606-23615 NN denotes treatment
T26036 23596-23605 VBG denotes following
T26035 23591-23595 NNP denotes PBMC
T26034 23585-23590 JJ denotes human
T26033 23582-23584 IN denotes by
T26032 23575-23581 NN denotes IL-1RA
T26031 23572-23574 IN denotes of
T26030 23561-23571 NN denotes production
T26029 23557-23560 DT denotes the
T26028 23549-23556 VBD denotes reduced
T26027 23535-23548 RB denotes significantly
T26026 23528-23534 NNP denotes NFIL-6
T26025 23524-23527 CC denotes and
T26024 23519-23523 NNP denotes NFAT
T26023 23517-23518 , denotes ,
T26022 23513-23517 NNP denotes NFκB
T26021 23510-23512 IN denotes of
T26020 23499-23509 NNP denotes Inhibition
T26019 23497-23498 , denotes ,
T26018 23496-23497 NNP denotes C
T26017 23494-23495 . denotes .
T26016 23493-23494 -RRB- denotes )
T26015 23492-23493 LS denotes 4
T26014 23490-23491 SYM denotes =
T26013 23488-23489 NN denotes n
T26012 23486-23487 , denotes ,
T26011 23483-23486 NN denotes gel
T26010 23468-23482 JJ denotes representative
T26009 23467-23468 -LRB- denotes (
T26008 23459-23466 NN denotes control
T26007 23446-23458 NN denotes housekeeping
T26006 23443-23445 IN denotes as
T26005 23438-23442 VBN denotes used
T26004 23435-23437 VBZ denotes is
T26003 23429-23434 NNP denotes GAPDH
T26002 23427-23428 . denotes .
T26001 23425-23427 NNP denotes GP
T26000 23422-23424 TO denotes to
T25999 23413-23421 VBN denotes compared
T25998 23409-23412 NNP denotes CyA
T25997 23406-23408 CC denotes or
T25996 23401-23405 NNP denotes CAPE
T25995 23399-23400 , denotes ,
T25994 23396-23399 NNP denotes CHX
T25993 23386-23395 VBG denotes following
T25992 23381-23385 NNP denotes mRNA
T25991 23374-23380 NNP denotes IL-1RA
T25990 23364-23373 VBN denotes decreased
T25989 23361-23363 IN denotes in
T25988 23352-23360 VBD denotes resulted
T25987 23345-23351 NNP denotes NFIL-6
T25986 23341-23344 CC denotes and
T25985 23336-23340 NNP denotes NFAT
T25984 23334-23335 , denotes ,
T25983 23330-23334 NNP denotes NFκB
T25982 23327-23329 IN denotes of
T25981 23316-23326 NNP denotes Inhibition
T25980 23314-23315 , denotes ,
T25979 23313-23314 NNP denotes B
T25978 23311-23312 . denotes .
T25977 23310-23311 -RRB- denotes )
T25976 23309-23310 LS denotes 4
T25975 23307-23308 SYM denotes =
T25974 23305-23306 FW denotes n
T25973 23304-23305 -LRB- denotes (
T25972 23300-23303 NNP denotes SEM
T25971 23298-23299 NN denotes ±
T25970 23293-23297 JJ denotes mean
T25969 23290-23292 IN denotes as
T25968 23284-23289 VBN denotes shown
T25967 23280-23283 VBP denotes are
T25966 23275-23279 NNS denotes Data
T25965 23273-23274 . denotes .
T25964 23272-23273 -RRB- denotes )
T25963 23268-23272 CD denotes 0.05
T25962 23266-23267 FW denotes <
T25961 23264-23265 FW denotes p
T25960 23262-23263 SYM denotes =
T25959 23260-23261 SYM denotes *
T25958 23259-23260 -LRB- denotes (
T25957 23249-23258 VBN denotes displayed
T25956 23246-23248 VBZ denotes is
T25955 23243-23245 NNP denotes GP
T25954 23240-23242 TO denotes to
T25953 23231-23239 VBN denotes compared
T25952 23226-23230 WRB denotes when
T25951 23215-23225 NN denotes inhibition
T25950 23205-23214 JJ denotes following
T25949 23197-23204 JJ denotes binding
T25948 23194-23196 IN denotes in
T25947 23185-23193 NN denotes decrease
T25946 23183-23184 DT denotes a
T25945 23173-23182 VBG denotes depicting
T25944 23171-23172 , denotes ,
T25943 23167-23171 NN denotes site
T25942 23158-23166 NNP denotes NFATP2/3
T25941 23154-23157 DT denotes the
T25940 23150-23153 IN denotes for
T25939 23142-23149 NN denotes summary
T25938 23132-23141 JJ denotes graphical
T25937 23130-23131 DT denotes a
T25936 23127-23129 IN denotes as
T25935 23122-23126 RB denotes well
T25934 23119-23121 RB denotes as
T25933 23117-23118 -RRB- denotes )
T25932 23112-23117 NN denotes water
T25931 23110-23111 : denotes :
T25930 23109-23110 CD denotes 8
T25929 23104-23108 NN denotes lane
T25928 23102-23103 , denotes ,
T25927 23097-23102 NN denotes oligo
T25926 23088-23096 NNP denotes NFATP2/3
T25925 23078-23087 JJ denotes unlabeled
T25924 23076-23077 NNP denotes +
T25923 23073-23075 NNP denotes GP
T25922 23071-23072 : denotes :
T25921 23070-23071 CD denotes 7
T25920 23065-23069 NN denotes lane
T25919 23063-23064 , denotes ,
T25918 23060-23063 NNP denotes CHX
T25917 23058-23059 NNP denotes +
T25916 23055-23057 NNP denotes GP
T25915 23053-23054 : denotes :
T25914 23052-23053 CD denotes 6
T25913 23047-23051 NN denotes lane
T25912 23045-23046 , denotes ,
T25911 23042-23045 NNP denotes CyA
T25910 23040-23041 NNP denotes +
T25909 23037-23039 NNP denotes GP
T25908 23035-23036 : denotes :
T25907 23034-23035 CD denotes 5
T25906 23029-23033 NN denotes lane
T25905 23027-23028 , denotes ,
T25904 23023-23027 NNP denotes CAPE
T25903 23021-23022 NNP denotes +
T25902 23018-23020 NNP denotes GP
T25901 23016-23017 : denotes :
T25900 23015-23016 CD denotes 4
T25899 23010-23014 NN denotes lane
T25898 23008-23009 , denotes ,
T25897 23003-23008 NN denotes oligo
T25896 22994-23002 CD denotes NFATP2/3
T25895 22986-22993 VBD denotes mutated
T25894 22976-22985 JJ denotes unlabeled
T25893 22974-22975 NNP denotes +
T25892 22971-22973 NNP denotes GP
T25891 22969-22970 : denotes :
T25890 22968-22969 CD denotes 3
T25889 22963-22967 NN denotes lane
T25888 22961-22962 , denotes ,
T25887 22959-22961 NNP denotes GP
T25886 22957-22958 : denotes :
T25885 22956-22957 CD denotes 2
T25884 22951-22955 NN denotes lane
T25883 22949-22950 , denotes ,
T25882 22942-22949 NN denotes control
T25881 22940-22941 : denotes :
T25880 22939-22940 CD denotes 1
T25879 22934-22938 NN denotes lane
T25878 22933-22934 -LRB- denotes (
T25877 22919-22932 NN denotes autoradiogram
T25876 22904-22918 JJ denotes representative
T25875 22902-22903 DT denotes A
T25874 22900-22901 , denotes ,
T25873 22899-22900 DT denotes A
T25872 22897-22898 . denotes .
T25871 22889-22897 NN denotes promoter
T25870 22882-22888 NN denotes IL-1RA
T25869 22878-22881 DT denotes the
T25868 22875-22877 TO denotes to
T25867 22867-22874 JJ denotes binding
T25866 22863-22866 NNP denotes DNA
T25865 22856-22862 NNP denotes NFIL-6
T25864 22852-22855 CC denotes and
T25863 22847-22851 NNP denotes NFAT
T25862 22845-22846 , denotes ,
T25861 22841-22845 NNP denotes NFκB
T25860 22830-22840 NNP denotes GP-induced
T25859 22827-22829 IN denotes of
T25858 22816-22826 NNP denotes Inhibition
T26074 23725-23726 . denotes .
T26073 23724-23725 -RRB- denotes )
T26072 23723-23724 LS denotes 3
T26071 23721-23722 SYM denotes =
T26070 23719-23720 FW denotes n
T26069 23718-23719 -LRB- denotes (
T26068 23714-23717 NNP denotes SEM
T26067 23712-23713 NN denotes ±
T26066 23707-23711 JJ denotes mean
T26065 23704-23706 IN denotes as
T26064 23698-23703 VBN denotes shown
T26063 23694-23697 VBP denotes are
T26062 23689-23693 NNS denotes Data
T26061 23687-23688 . denotes .
T26060 23686-23687 -RRB- denotes )
T26059 23682-23686 CD denotes 0.01
T26058 23680-23681 FW denotes <
T26057 23678-23679 FW denotes p
T26056 23676-23677 SYM denotes =
T26055 23673-23675 SYM denotes **
T26054 23671-23672 : denotes ;
T26053 23667-23671 CD denotes 0.05
T26052 23665-23666 FW denotes <
T26051 23663-23664 FW denotes p
T26050 23661-23662 SYM denotes =
T26049 23659-23660 SYM denotes *
T25321 21537-21538 . denotes .
T25320 21536-21537 -RRB- denotes )
T25319 21535-21536 LS denotes 3
T25318 21533-21534 SYM denotes =
T25317 21531-21532 FW denotes n
T25316 21530-21531 -LRB- denotes (
T25315 21526-21529 NNP denotes SEM
T25314 21524-21525 NN denotes ±
T25313 21519-21523 JJ denotes mean
T25312 21516-21518 IN denotes as
T25311 21510-21515 VBN denotes shown
T25310 21506-21509 VBP denotes are
T25309 21501-21505 NNS denotes Data
T25308 21499-21500 . denotes .
T25307 21498-21499 -RRB- denotes )
T25306 21494-21498 CD denotes 0.05
T25305 21492-21493 FW denotes <
T25304 21490-21491 FW denotes p
T25303 21488-21489 SYM denotes =
T25302 21486-21487 SYM denotes *
T25301 21485-21486 -LRB- denotes (
T25300 21479-21484 NN denotes IL-1β
T25299 21476-21478 IN denotes of
T25298 21471-21475 IN denotes than
T25297 21464-21470 NN denotes IL-1RA
T25296 21461-21463 IN denotes of
T25295 21450-21460 NN denotes production
T25294 21443-21449 JJR denotes higher
T25293 21441-21442 FW denotes a
T25292 21436-21440 FW denotes i.e.
T25291 21434-21435 , denotes ,
T25290 21433-21434 NN denotes h
T25289 21430-21432 CD denotes 24
T25288 21426-21429 CC denotes and
T25287 21424-21425 NN denotes h
T25286 21421-21423 CD denotes 18
T25285 21418-21420 IN denotes at
T25284 21412-21417 NN denotes ratio
T25283 21404-21411 VBN denotes reduced
T25282 21399-21403 VBP denotes fold
T25281 21395-21398 CD denotes 100
T25280 21392-21394 CD denotes 10
T25279 21386-21391 IN denotes about
T25278 21383-21385 DT denotes an
T25277 21380-21382 IN denotes by
T25276 21367-21379 VBN denotes demonstrated
T25275 21364-21366 IN denotes as
T25274 21362-21363 , denotes ,
T25273 21360-21362 NNP denotes GP
T25272 21357-21359 IN denotes of
T25271 21350-21356 NN denotes action
T25270 21332-21349 JJ denotes anti-inflammatory
T25269 21321-21331 JJ denotes pronounced
T25268 21319-21320 DT denotes a
T25267 21310-21318 VBD denotes observed
T25266 21307-21309 PRP denotes we
T25265 21300-21306 NNP denotes TSST-1
T25264 21298-21299 FW denotes +
T25263 21295-21297 NNP denotes GP
T25262 21292-21294 FW denotes vs
T25261 21290-21291 . denotes .
T25260 21286-21290 NN denotes calc
T25259 21283-21285 CD denotes -1
T25258 21276-21283 NNP denotes GP/TSST
T25257 21273-21275 CC denotes or
T25256 21266-21272 CD denotes TSST-1
T25255 21263-21265 TO denotes to
T25254 21255-21262 NN denotes respect
T25253 21250-21254 IN denotes With
T25252 21247-21249 NN denotes h.
T25251 21244-21246 CD denotes 48
T25250 21239-21243 IN denotes over
T25249 21233-21238 NN denotes ratio
T25248 21226-21232 NN denotes IL-1RA
T25247 21225-21226 NN denotes /
T25246 21220-21225 JJ denotes IL-1β
T25245 21216-21219 DT denotes the
T25244 21213-21215 IN denotes in
T25243 21201-21212 NNS denotes alterations
T25242 21189-21200 JJ denotes significant
T25241 21184-21188 VB denotes find
T25240 21180-21183 RB denotes not
T25239 21176-21179 VBD denotes did
T25238 21173-21175 PRP denotes we
T25237 21169-21172 NNP denotes LPS
T25236 21167-21168 FW denotes +
T25235 21164-21166 NNP denotes GP
T25234 21161-21163 FW denotes vs
T25233 21159-21160 . denotes .
T25232 21155-21159 NN denotes calc
T25231 21148-21154 NNP denotes GP/LPS
T25230 21145-21147 CC denotes or
T25229 21141-21144 NNP denotes LPS
T25228 21131-21140 VBG denotes comparing
T24595 19359-19365 NNP denotes GP/LPS
T24594 19355-19358 IN denotes for
T24593 19348-19354 NNS denotes values
T24592 19336-19347 JJ denotes theoretical
T24591 19332-19335 DT denotes the
T24590 19322-19331 VBG denotes depicting
T24589 19317-19321 NNS denotes Bars
T24588 19315-19316 . denotes .
T24587 19307-19315 NN denotes promoter
T24586 19300-19306 NN denotes IL-1RA
T24585 19296-19299 DT denotes the
T24584 19293-19295 IN denotes in
T24583 19288-19292 NN denotes site
T24582 19284-19287 DT denotes the
T24581 19281-19283 TO denotes to
T24580 19272-19280 NN denotes activity
T24579 19264-19271 JJ denotes binding
T24578 19255-19263 NNP denotes NFAT-DNA
T24577 19246-19254 JJ denotes elevated
T24576 19242-19245 DT denotes the
T24575 19239-19241 IN denotes of
T24574 19224-19238 NN denotes representation
T24573 19214-19223 NNP denotes Schematic
T24572 19211-19213 NNP denotes C.
T24571 19210-19211 CD denotes °
T24570 19208-19210 CD denotes 37
T24569 19205-19207 IN denotes at
T24568 19203-19204 NN denotes h
T24567 19201-19202 CD denotes 1
T24566 19197-19200 IN denotes for
T24565 19193-19196 NNP denotes LPS
T24564 19191-19192 NNP denotes +
T24563 19188-19190 NNP denotes GP
T24562 19184-19187 CC denotes and
T24561 19177-19183 NNP denotes TSST-1
T24560 19175-19176 NNP denotes +
T24559 19172-19174 NNP denotes GP
T24558 19170-19171 , denotes ,
T24557 19168-19170 NNP denotes GP
T24556 19166-19167 , denotes ,
T24555 19160-19166 NNP denotes TSST-1
T24554 19158-19159 , denotes ,
T24553 19155-19158 NNP denotes LPS
T24552 19153-19154 , denotes ,
T24551 19146-19153 NN denotes control
T24550 19139-19145 NN denotes medium
T24549 19134-19138 IN denotes with
T24548 19124-19133 VBN denotes incubated
T24547 19119-19123 VBD denotes were
T24546 19114-19118 NNP denotes PBMC
T24545 19108-19113 NNP denotes Human
T24544 19106-19107 . denotes .
T24543 19105-19106 -RRB- denotes )
T24542 19101-19105 CD denotes 0.05
T24541 19099-19100 FW denotes <
T24540 19097-19098 FW denotes p
T24539 19095-19096 SYM denotes =
T24538 19093-19094 SYM denotes *
T24537 19092-19093 -LRB- denotes (
T24536 19085-19091 NNP denotes TSST-1
T24535 19081-19084 CC denotes and
T24534 19078-19080 NNP denotes GP
T24533 19073-19077 DT denotes both
T24532 19070-19072 TO denotes to
T24531 19068-19069 , denotes ,
T24530 19064-19068 NN denotes case
T24529 19057-19063 JJ denotes latter
T24528 19053-19056 DT denotes the
T24527 19050-19052 IN denotes in
T24526 19048-19049 , denotes ,
T24525 19045-19048 CC denotes and
T24524 19042-19044 NNP denotes GP
T24523 19039-19041 TO denotes to
T24522 19030-19038 VBN denotes compared
T24521 19025-19029 WRB denotes when
T24520 19023-19024 , denotes ,
T24519 19017-19023 NNP denotes TSST-1
T24518 19015-19016 NNP denotes +
T24517 19012-19014 NNP denotes GP
T24516 19008-19011 CC denotes and
T24515 19004-19007 NNP denotes LPS
T24514 19002-19003 NNP denotes +
T24513 18999-19001 NNP denotes GP
T24512 18995-18998 IN denotes for
T24511 18982-18994 JJ denotes up-regulated
T24510 18978-18981 VBD denotes was
T24509 18970-18977 VBG denotes Binding
T24508 18968-18969 . denotes .
T24507 18960-18968 NN denotes promoter
T24506 18953-18959 NN denotes IL-1RA
T24505 18949-18952 DT denotes the
T24504 18946-18948 IN denotes in
T24503 18941-18945 NN denotes site
T24502 18932-18940 NNP denotes NFATP2/3
T24501 18928-18931 JJ denotes new
T24500 18926-18927 DT denotes a
T24499 18923-18925 TO denotes to
T24498 18915-18922 JJ denotes binding
T24497 18911-18914 NNP denotes DNA
T24496 18896-18910 JJ denotes TSST-1-induced
T24495 18886-18895 VBD denotes modulated
T24494 18883-18885 NNP denotes GP
T24108 18871-18872 . denotes .
T24107 18870-18871 -RRB- denotes )
T24106 18863-18870 NNS denotes methods
T24105 18859-18862 VB denotes see
T24104 18858-18859 -LRB- denotes (
T24103 18853-18857 NNP denotes EMSA
T24102 18850-18852 IN denotes by
T24101 18841-18849 VBN denotes assessed
T24100 18837-18840 VBD denotes was
T24099 18829-18836 JJ denotes binding
T24098 18825-18828 NNP denotes DNA
T24097 18823-18824 . denotes .
T24096 18822-18823 -RRB- denotes )
T24095 18821-18822 CD denotes 6
T24094 18819-18820 SYM denotes =
T24093 18817-18818 FW denotes n
T24092 18816-18817 -LRB- denotes (
T24091 18812-18815 NNP denotes SEM
T24090 18810-18811 CD denotes ±
T24089 18808-18809 CD denotes 1
T24088 18805-18807 TO denotes to
T24087 18799-18804 JJ denotes equal
T24086 18795-18798 VBN denotes set
T24085 18790-18794 VBD denotes were
T24084 18783-18789 NNS denotes levels
T24083 18775-18782 NN denotes control
T24082 18768-18774 NN denotes Medium
T24081 18766-18767 . denotes .
T24080 18765-18766 -RRB- denotes )
T24079 18761-18765 CD denotes 0.01
T24078 18759-18760 FW denotes <
T24077 18757-18758 FW denotes p
T24076 18755-18756 SYM denotes =
T24075 18752-18754 SYM denotes **
T24074 18750-18751 : denotes ;
T24073 18746-18750 CD denotes 0.05
T24072 18744-18745 FW denotes <
T24071 18742-18743 FW denotes p
T24070 18740-18741 SYM denotes =
T24069 18738-18739 SYM denotes *
T24068 18737-18738 -LRB- denotes (
T24067 18724-18736 RB denotes respectively
T24066 18722-18723 , denotes ,
T24065 18717-18722 NN denotes calc.
T24064 18714-18716 CD denotes -1
T24063 18707-18714 NNP denotes GP/TSST
T24062 18704-18706 CC denotes or
T24061 18702-18703 . denotes .
T24060 18698-18702 NN denotes calc
T24059 18691-18697 NNP denotes GP/LPS
T24058 18689-18690 , denotes ,
T24057 18687-18689 NNP denotes GP
T24056 18685-18686 , denotes ,
T24055 18679-18685 NNP denotes TSST-1
T24054 18677-18678 , denotes ,
T24053 18674-18677 NNP denotes LPS
T24052 18671-18673 TO denotes to
T24051 18662-18670 VBN denotes compared
T24050 18657-18661 WRB denotes when
T24049 18655-18656 , denotes ,
T24048 18649-18655 NNP denotes TSST-1
T24047 18647-18648 NNP denotes +
T24046 18644-18646 NNP denotes GP
T24045 18640-18643 CC denotes and
T24044 18636-18639 NNP denotes LPS
T24043 18634-18635 NNP denotes +
T24042 18631-18633 NNP denotes GP
T24041 18627-18630 IN denotes for
T24040 18618-18626 VBN denotes enhanced
T24039 18614-18617 VBD denotes was
T24038 18606-18613 VBG denotes Binding
T24037 18604-18605 . denotes .
T24036 18596-18604 NN denotes promoter
T24035 18589-18595 NN denotes IL-1RA
T24034 18585-18588 DT denotes the
T24033 18582-18584 IN denotes in
T24032 18577-18581 NN denotes site
T24031 18571-18576 JJ denotes NFκB3
T24030 18567-18570 JJ denotes new
T24029 18565-18566 DT denotes a
T24028 18562-18564 TO denotes to
T24027 18554-18561 JJ denotes binding
T24026 18539-18553 JJ denotes TSST-1-induced
T24025 18535-18538 CC denotes and
T24024 18533-18534 : denotes -
T24023 18530-18533 NNP denotes LPS
T24022 18520-18529 VBD denotes modulated
T24021 18517-18519 NNP denotes GP
T25227 21126-21130 WRB denotes When
T25226 21124-21125 . denotes .
T25225 21123-21124 NN denotes h
T25224 21120-21122 CD denotes 24
T25223 21117-21119 TO denotes to
T25222 21114-21116 IN denotes up
T25221 21107-21113 NN denotes IL-1RA
T25220 21102-21106 IN denotes than
T25219 21096-21101 JJ denotes IL-1β
T25218 21091-21095 RBR denotes more
T25217 21080-21090 VBG denotes generating
T25216 21077-21079 IN denotes in
T25215 21068-21076 VBD denotes resulted
T25214 21057-21067 NNS denotes treatments
T25213 21053-21056 NNP denotes LPS
T25212 21051-21052 NNP denotes +
T25211 21048-21050 NNP denotes GP
T25210 21044-21047 CC denotes and
T25209 21040-21043 NNP denotes LPS
T25208 21038-21039 . denotes .
T25207 21034-21038 NN denotes calc
T25206 21031-21033 CD denotes -1
T25205 21024-21031 NNP denotes GP/TSST
T25204 21021-21023 CC denotes or
T25203 21014-21020 NNP denotes TSST-1
T25202 21012-21013 NNP denotes +
T25201 21009-21011 NNP denotes GP
T25200 21007-21008 , denotes ,
T25199 21002-21007 NNP denotes calc.
T25198 20995-21001 NNP denotes GP/LPS
T25197 20993-20994 , denotes ,
T25196 20990-20993 NNP denotes LPS
T25195 20988-20989 NNP denotes +
T25194 20985-20987 NNP denotes GP
T25193 20983-20984 , denotes ,
T25192 20977-20983 NNP denotes TSST-1
T25191 20975-20976 , denotes ,
T25190 20972-20975 NNP denotes LPS
T25189 20967-20971 IN denotes with
T25188 20962-20966 NNP denotes PBMC
T25187 20956-20961 JJ denotes human
T25186 20953-20955 IN denotes of
T25185 20942-20952 NN denotes incubation
T25184 20932-20941 VBG denotes following
T25183 20926-20931 NN denotes ratio
T25182 20919-20925 NN denotes IL-1RA
T25181 20918-20919 NN denotes /
T25180 20913-20918 JJ denotes IL-1β
T25179 20909-20912 DT denotes the
T25178 20906-20908 IN denotes of
T25177 20904-20905 -RRB- denotes )
T25176 20903-20904 NN denotes h
T25175 20900-20902 CD denotes 48
T25174 20899-20900 -LRB- denotes (
T25173 20892-20898 NN denotes course
T25172 20887-20891 NNP denotes Time
T25171 20885-20886 . denotes .
T25170 20879-20885 NNP denotes TSST-1
T25169 20876-20878 TO denotes to
T25168 20867-20875 VBN denotes compared
T25167 20862-20866 WRB denotes when
T25166 20855-20861 NNP denotes TSST-1
T25165 20853-20854 NNP denotes +
T25164 20850-20852 NNP denotes GP
T25163 20840-20849 VBG denotes following
T25162 20834-20839 NN denotes ratio
T25161 20827-20833 NN denotes IL-1RA
T25160 20826-20827 NN denotes /
T25159 20821-20826 JJ denotes IL-1β
T25158 20811-20820 VBN denotes Decreased
T24675 19655-19656 . denotes .
T24674 19654-19655 -RRB- denotes )
T24673 19648-19654 NNP denotes TSST-1
T24672 19646-19647 NNP denotes +
T24671 19643-19645 NNP denotes GP
T24670 19641-19642 : denotes :
T24669 19640-19641 CD denotes 7
T24668 19635-19639 NN denotes lane
T24667 19633-19634 : denotes ;
T24666 19630-19633 NNP denotes LPS
T24665 19628-19629 NNP denotes +
T24664 19625-19627 NNP denotes GP
T24663 19623-19624 : denotes :
T24662 19622-19623 CD denotes 6
T24661 19617-19621 NN denotes lane
T24660 19615-19616 , denotes ,
T24659 19609-19615 NN denotes TSST-1
T24658 19607-19608 : denotes :
T24657 19606-19607 CD denotes 5
T24656 19601-19605 NN denotes lane
T24655 19599-19600 : denotes ;
T24654 19596-19599 NNP denotes LPS
T24653 19594-19595 : denotes :
T24652 19593-19594 CD denotes 4
T24651 19588-19592 NN denotes lane
T24650 19586-19587 : denotes ;
T24649 19584-19586 NNP denotes GP
T24648 19582-19583 : denotes :
T24647 19581-19582 CD denotes 3
T24646 19576-19580 NN denotes lane
T24645 19574-19575 : denotes ;
T24644 19567-19574 NN denotes control
T24643 19560-19566 NN denotes medium
T24642 19558-19559 : denotes :
T24641 19557-19558 CD denotes 2
T24640 19552-19556 NN denotes lane
T24639 19550-19551 : denotes ;
T24638 19545-19550 NN denotes water
T24637 19543-19544 : denotes :
T24636 19542-19543 CD denotes 1
T24635 19537-19541 NN denotes lane
T24634 19536-19537 -LRB- denotes (
T24633 19530-19535 NN denotes panel
T24632 19524-19529 JJR denotes lower
T24631 19520-19523 DT denotes the
T24630 19517-19519 IN denotes in
T24629 19511-19516 VBN denotes shown
T24628 19508-19510 VBZ denotes is
T24627 19497-19507 NN denotes experiment
T24626 19482-19496 NN denotes representative
T24625 19480-19481 DT denotes a
T24624 19477-19479 IN denotes of
T24623 19463-19476 NN denotes autoradiogram
T24622 19460-19462 DT denotes An
T24621 19458-19459 . denotes .
T24620 19457-19458 -RRB- denotes )
T24619 19456-19457 CD denotes 6
T24618 19454-19455 SYM denotes =
T24617 19452-19453 FW denotes n
T24616 19451-19452 -LRB- denotes (
T24615 19447-19450 NNP denotes SEM
T24614 19445-19446 CD denotes ±
T24613 19443-19444 CD denotes 1
T24612 19440-19442 TO denotes to
T24611 19434-19439 JJ denotes equal
T24610 19430-19433 VBN denotes set
T24609 19425-19429 VBD denotes were
T24608 19418-19424 NNS denotes levels
T24607 19410-19417 NN denotes control
T24606 19403-19409 NN denotes Medium
T24605 19401-19402 . denotes .
T24604 19396-19401 VBN denotes added
T24603 19392-19395 VBP denotes are
T24602 19390-19391 . denotes .
T24601 19386-19390 NN denotes calc
T24600 19383-19385 CD denotes -1
T24599 19376-19383 NNP denotes GP/TSST
T24598 19372-19375 CC denotes and
T24597 19370-19371 . denotes .
T24596 19366-19370 NN denotes calc
T23722 13389-13390 . denotes .
T23721 13388-13389 -RRB- denotes )
T23720 13387-13388 LS denotes 3
T23719 13385-13386 SYM denotes =
T23718 13383-13384 FW denotes n
T23717 13382-13383 -LRB- denotes (
T23716 13378-13381 NNP denotes SEM
T23715 13376-13377 NN denotes ±
T23714 13371-13375 JJ denotes mean
T23713 13368-13370 IN denotes as
T23712 13362-13367 VBN denotes shown
T23711 13358-13361 VBP denotes are
T23710 13354-13357 CC denotes and
T23709 13348-13353 NNP denotes Elisa
T23708 13345-13347 IN denotes by
T23707 13336-13344 VBN denotes obtained
T23706 13331-13335 VBD denotes were
T23705 13318-13330 JJ denotes supernatnant
T23704 13314-13317 DT denotes the
T23703 13311-13313 IN denotes in
T23702 13304-13310 NNS denotes levels
T23701 13297-13303 NN denotes IL-1RA
T23700 13295-13296 . denotes .
T23699 13287-13295 VBN denotes included
T23698 13283-13286 VBP denotes are
T23697 13281-13282 . denotes .
T23696 13277-13281 NN denotes calc
T23695 13274-13276 CD denotes -1
T23694 13267-13274 NNP denotes GP/TSST
T23693 13263-13266 CC denotes and
T23692 13261-13262 . denotes .
T23691 13257-13261 NN denotes calc
T23690 13250-13256 NNP denotes GP/LPS
T23689 13246-13249 IN denotes for
T23688 13239-13245 NNS denotes values
T23687 13227-13238 JJ denotes theoretical
T23686 13223-13226 DT denotes the
T23685 13213-13222 VBG denotes depicting
T23684 13206-13212 NNS denotes Graphs
T23683 13204-13205 . denotes .
T23682 13203-13204 -RRB- denotes )
T23681 13199-13203 CD denotes 0.05
T23680 13197-13198 FW denotes <
T23679 13195-13196 FW denotes p
T23678 13193-13194 SYM denotes =
T23677 13191-13192 SYM denotes *
T23676 13190-13191 -LRB- denotes (
T23675 13187-13189 NNP denotes GP
T23674 13183-13186 CC denotes and
T23673 13176-13182 CD denotes TSST-1
T23672 13172-13175 IN denotes for
T23671 13165-13171 NNS denotes values
T23670 13158-13164 JJ denotes single
T23669 13154-13157 DT denotes the
T23668 13151-13153 IN denotes of
T23667 13142-13150 NN denotes addition
T23666 13139-13141 DT denotes an
T23665 13136-13138 TO denotes to
T23664 13127-13135 VBN denotes compared
T23663 13122-13126 WRB denotes when
T23662 13111-13121 NN denotes production
T23661 13104-13110 NN denotes IL-1RA
T23660 13097-13103 JJR denotes higher
T23659 13095-13096 FW denotes a
T23658 13090-13094 FW denotes i.e.
T23657 13088-13089 , denotes ,
T23656 13082-13088 NN denotes effect
T23655 13070-13081 JJ denotes synergistic
T23654 13068-13069 DT denotes a
T23653 13065-13067 TO denotes to
T23652 13061-13064 VBD denotes led
T23651 13054-13060 NNP denotes TSST-1
T23650 13052-13053 NNP denotes +
T23649 13049-13051 NNP denotes GP
T23648 13044-13048 IN denotes with
T23647 13039-13043 NNP denotes PBMC
T23646 13036-13038 IN denotes of
T23645 13026-13035 NN denotes treatment
T23644 13013-13025 JJ denotes simultaneous
T23643 13011-13012 DT denotes a
T23642 13009-13010 VBP denotes h
T23641 13006-13008 CD denotes 48
T23640 13002-13005 CC denotes and
T23639 13000-13001 NN denotes h
T23638 12997-12999 CD denotes 18
T23637 12989-12996 IN denotes Between
T23636 12987-12988 . denotes .
T23635 12984-12987 NNP denotes LPS
T23634 12982-12983 NNP denotes +
T23633 12979-12981 NNP denotes GP
T23632 12975-12978 CC denotes and
T23631 12971-12974 NNP denotes LPS
T23630 12968-12970 NN denotes ng
T23629 12964-12967 CD denotes 250
T23628 12962-12963 , denotes ,
T23627 12956-12962 NNP denotes TSST-1
T23626 12954-12955 NNP denotes +
T23625 12951-12953 NNP denotes GP
T23624 12949-12950 , denotes ,
T23623 12943-12949 NN denotes TSST-1
T23622 12940-12942 NN denotes ng
T23621 12936-12939 CD denotes 250
T23620 12934-12935 , denotes ,
T23619 12932-12934 NNP denotes GP
T23618 12929-12931 NN denotes μg
T23565 12712-12715 VBP denotes are
T23564 12708-12711 CC denotes and
T23563 12702-12707 NNP denotes Elisa
T23562 12699-12701 IN denotes by
T23561 12690-12698 VBN denotes obtained
T23560 12685-12689 VBD denotes were
T23559 12672-12684 JJ denotes supernatnant
T23558 12668-12671 DT denotes the
T23557 12665-12667 IN denotes in
T23556 12658-12664 NNS denotes levels
T23555 12652-12657 JJ denotes IL-1β
T23554 12650-12651 . denotes .
T23553 12645-12650 VBN denotes shown
T23552 12640-12644 RB denotes also
T23551 12636-12639 VBP denotes are
T23550 12634-12635 . denotes .
T23549 12630-12634 NN denotes calc
T23548 12627-12629 CD denotes -1
T23547 12620-12627 NNP denotes GP/TSST
T23546 12616-12619 CC denotes and
T23545 12614-12615 . denotes .
T23544 12610-12614 NN denotes calc
T23543 12603-12609 NNP denotes GP/LPS
T23542 12599-12602 IN denotes for
T23541 12592-12598 NNS denotes values
T23540 12580-12591 JJ denotes theoretical
T23539 12576-12579 DT denotes the
T23538 12566-12575 VBG denotes depicting
T23537 12559-12565 NNS denotes Graphs
T23536 12557-12558 . denotes .
T23535 12556-12557 -RRB- denotes )
T23534 12552-12556 CD denotes 0.05
T23533 12550-12551 FW denotes <
T23532 12548-12549 FW denotes p
T23531 12546-12547 SYM denotes =
T23530 12544-12545 SYM denotes *
T23529 12543-12544 -LRB- denotes (
T23528 12536-12542 NNP denotes TSST-1
T23527 12533-12535 TO denotes to
T23526 12524-12532 VBN denotes compared
T23525 12519-12523 WRB denotes when
T23524 12512-12518 NNP denotes TSST-1
T23523 12510-12511 NNP denotes +
T23522 12507-12509 NNP denotes GP
T23521 12497-12506 VBG denotes following
T23520 12486-12496 NN denotes production
T23519 12480-12485 JJ denotes IL-1β
T23518 12477-12479 IN denotes in
T23517 12467-12476 NN denotes reduction
T23516 12460-12466 JJ denotes marked
T23515 12458-12459 DT denotes a
T23514 12454-12457 VBD denotes was
T23513 12448-12453 EX denotes there
T23512 12446-12447 NN denotes h
T23511 12443-12445 CD denotes 24
T23510 12439-12442 CC denotes and
T23509 12437-12438 NN denotes h
T23508 12434-12436 CD denotes 18
T23507 12431-12433 IN denotes At
T23506 12429-12430 . denotes .
T23505 12426-12429 NNP denotes LPS
T23504 12424-12425 NNP denotes +
T23503 12421-12423 NNP denotes GP
T23502 12417-12420 CC denotes and
T23501 12413-12416 NNP denotes LPS
T23500 12410-12412 NN denotes ng
T23499 12406-12409 CD denotes 250
T23498 12404-12405 , denotes ,
T23497 12398-12404 NNP denotes TSST-1
T23496 12396-12397 NNP denotes +
T23495 12393-12395 NNP denotes GP
T23494 12391-12392 , denotes ,
T23493 12385-12391 NN denotes TSST-1
T23492 12382-12384 NN denotes ng
T23491 12378-12381 CD denotes 250
T23490 12376-12377 , denotes ,
T23489 12374-12376 NNP denotes GP
T23488 12371-12373 NN denotes μg
T23487 12367-12370 CD denotes 100
T23486 12365-12366 , denotes ,
T23485 12358-12365 NN denotes control
T23484 12351-12357 NN denotes medium
T23483 12346-12350 IN denotes with
T23482 12336-12345 VBD denotes incubated
T23481 12331-12335 NNP denotes PBMC
T23480 12325-12330 JJ denotes human
T23479 12322-12324 IN denotes by
T23478 12320-12321 -RRB- denotes )
T23477 12315-12320 NN denotes pg/ml
T23476 12314-12315 -LRB- denotes (
T23475 12303-12313 NN denotes production
T23474 12297-12302 NN denotes IL-1β
T23473 12294-12296 IN denotes of
T23472 12292-12293 -RRB- denotes )
T23471 12291-12292 NN denotes h
T23470 12288-12290 CD denotes 48
T23469 12287-12288 -LRB- denotes (
T23468 12280-12286 NN denotes course
T23467 12275-12279 NNP denotes Time
T23466 12273-12274 . denotes .
T23465 12267-12273 NNP denotes TSST-1
T23464 12264-12266 TO denotes to
T23463 12255-12263 VBN denotes compared
T23462 12250-12254 WRB denotes when
T23461 12243-12249 NNP denotes TSST-1
T23460 12241-12242 NNP denotes +
T23459 12238-12240 NNP denotes GP
T23458 12228-12237 VBG denotes following
T23457 12226-12227 -RRB- denotes )
T23456 12225-12226 NN denotes h
T23455 12222-12224 CD denotes 24
T23454 12218-12219 NN denotes h
T23453 12215-12217 CD denotes 12
T23452 12214-12215 -LRB- denotes (
T23451 12199-12213 VBN denotes down-regulated
T23450 12195-12198 VBD denotes was
T23449 12189-12194 NN denotes IL-1β
T23448 12187-12188 , denotes ,
T23447 12186-12187 DT denotes A
T23617 12925-12928 CD denotes 100
T23616 12923-12924 , denotes ,
T23615 12916-12923 NN denotes control
T23614 12909-12915 NN denotes medium
T23613 12904-12908 IN denotes with
T23612 12894-12903 VBD denotes incubated
T23611 12889-12893 NNP denotes PBMC
T23610 12883-12888 JJ denotes human
T23609 12880-12882 IN denotes by
T23608 12878-12879 -RRB- denotes )
T23607 12873-12878 NN denotes pg/ml
T23606 12872-12873 -LRB- denotes (
T23605 12861-12871 NN denotes production
T23604 12854-12860 NN denotes IL-1RA
T23603 12851-12853 IN denotes of
T23602 12849-12850 -RRB- denotes )
T23601 12848-12849 NN denotes h
T23600 12845-12847 CD denotes 48
T23599 12844-12845 -LRB- denotes (
T23598 12837-12843 NN denotes course
T23597 12832-12836 NNP denotes Time
T23596 12830-12831 . denotes .
T23595 12824-12830 NNP denotes TSST-1
T23594 12821-12823 TO denotes to
T23593 12812-12820 VBN denotes compared
T23592 12807-12811 WRB denotes when
T23591 12805-12806 -RRB- denotes )
T23590 12804-12805 NN denotes h
T23589 12801-12803 CD denotes 48
T23588 12797-12798 NN denotes h
T23587 12794-12796 CD denotes 12
T23586 12793-12794 -LRB- denotes (
T23585 12786-12792 NNP denotes TSST-1
T23584 12784-12785 NNP denotes +
T23583 12781-12783 NNP denotes GP
T23582 12771-12780 VBG denotes following
T23581 12759-12770 VBN denotes exaggerated
T23580 12755-12758 VBD denotes was
T23579 12748-12754 NNP denotes IL-1RA
T23578 12746-12747 , denotes ,
T23577 12745-12746 NNP denotes B
T23576 12743-12744 . denotes .
T23575 12742-12743 -RRB- denotes )
T23574 12741-12742 LS denotes 3
T23573 12739-12740 SYM denotes =
T23572 12737-12738 FW denotes n
T23571 12736-12737 -LRB- denotes (
T23570 12732-12735 NNP denotes SEM
T23569 12730-12731 NN denotes ±
T23568 12725-12729 JJ denotes mean
T23567 12722-12724 IN denotes as
T23566 12716-12721 VBN denotes shown
T22752 10778-10779 -RRB- denotes )
T22751 10777-10778 LS denotes 3
T22750 10775-10776 SYM denotes =
T22749 10773-10774 FW denotes n
T22748 10772-10773 -LRB- denotes (
T22747 10766-10771 VBN denotes shown
T22746 10763-10765 VBZ denotes is
T22745 10757-10762 NN denotes panel
T22744 10751-10756 JJR denotes lower
T22743 10747-10750 DT denotes the
T22742 10744-10746 IN denotes in
T22741 10742-10743 -RRB- denotes )
T22740 10740-10742 CD denotes c1
T22739 10738-10739 , denotes ,
T22738 10736-10738 CD denotes c2
T22737 10731-10735 NNP denotes NFAT
T22736 10727-10730 CC denotes and
T22735 10723-10726 CD denotes p50
T22734 10721-10722 , denotes ,
T22733 10718-10721 CD denotes p65
T22732 10713-10717 NNP denotes NFκB
T22731 10709-10712 IN denotes for
T22730 10700-10708 JJ denotes positive
T22729 10699-10700 -LRB- denotes (
T22728 10694-10698 NNP denotes PBMC
T22727 10683-10693 JJ denotes GP-treated
T22720 10641-10646 NN denotes panel
T22719 10635-10640 JJ denotes upper
T22718 10631-10634 DT denotes the
T22717 10628-10630 IN denotes in
T22716 10626-10627 -RRB- denotes )
T22715 10624-10626 NN denotes c2
T22714 10622-10623 , denotes ,
T22713 10616-10622 NNP denotes NFATc1
T22712 10612-10615 IN denotes for
T22711 10608-10611 CC denotes and
T22710 10604-10607 CD denotes p65
T22709 10602-10603 , denotes ,
T22708 10599-10602 CD denotes p50
T22707 10594-10598 NNP denotes NFκB
T22706 10590-10593 IN denotes for
T22705 10581-10589 JJ denotes positive
T22704 10575-10580 NNS denotes cells
T22703 10568-10574 NNP denotes Jurkat
T22702 10556-10567 JJ denotes PMA-treated
T22701 10553-10555 IN denotes of
T22700 10544-10552 NNS denotes extracts
T22699 10536-10543 JJ denotes nuclear
T22698 10534-10535 : denotes ;
T22697 10529-10534 NN denotes c-rel
T22696 10527-10528 , denotes ,
T22695 10524-10527 CD denotes p52
T22694 10519-10523 NNP denotes NFκB
T22693 10510-10518 NNS denotes proteins
T22692 10498-10509 JJ denotes recombinant
T22691 10497-10498 -LRB- denotes (
T22690 10488-10496 NNS denotes controls
T22689 10479-10487 JJ denotes positive
T22688 10475-10478 CC denotes and
T22687 10466-10474 JJ denotes negative
T22686 10463-10465 IN denotes of
T22685 10454-10462 NN denotes staining
T22684 10446-10453 VBG denotes showing
T22683 10441-10445 NN denotes blot
T22682 10437-10440 VBP denotes dot
T22681 10422-10436 NN denotes representative
T22680 10420-10421 DT denotes A
T22679 10418-10419 . denotes .
T22678 10409-10418 VBN denotes performed
T22677 10405-10408 VBD denotes was
T22676 10400-10404 NN denotes blot
T22675 10398-10399 -RRB- denotes )
T22674 10395-10398 VB denotes dot
T22673 10394-10395 -LRB- denotes (
T22672 10388-10394 NN denotes immuno
T22671 10385-10387 DT denotes an
T22670 10383-10384 , denotes ,
T22669 10379-10383 NNP denotes NFAT
T22668 10375-10378 CC denotes and
T22667 10370-10374 NNP denotes NFκB
T22666 10367-10369 TO denotes to
T22665 10359-10366 VBN denotes related
T22664 10354-10358 VBD denotes were
T22663 10351-10353 NNP denotes GP
T22662 10348-10350 IN denotes by
T22661 10338-10347 VBN denotes activated
T22660 10329-10337 NNS denotes proteins
T22659 10321-10328 JJ denotes binding
T22658 10317-10320 NNP denotes DNA
T22657 10313-10316 DT denotes the
T22656 10305-10312 IN denotes whether
T22655 10295-10304 VB denotes determine
T22654 10292-10294 TO denotes to
T22653 10286-10291 NN denotes order
T22652 10283-10285 IN denotes In
T22651 10281-10282 . denotes .
T22650 10274-10281 JJ denotes binding
T22649 10270-10273 NNP denotes DNA
T22648 10259-10269 JJ denotes GP-induced
T22647 10256-10258 IN denotes in
T22646 10247-10255 VBN denotes involved
T22645 10242-10246 VBD denotes were
T22644 10232-10241 NNP denotes NFATc2/c1
T22643 10228-10231 CC denotes and
T22642 10220-10227 CD denotes p65/p50
T22641 10215-10219 NNP denotes NFκB
T22185 10199-10200 SYM denotes =
T22184 10197-10198 FW denotes n
T22183 10196-10197 -LRB- denotes (
T22182 10188-10195 NN denotes control
T22181 10181-10187 JJ denotes medium
T22180 10178-10180 TO denotes to
T22179 10170-10177 NN denotes respect
T22178 10165-10169 IN denotes with
T22177 10159-10164 VBN denotes shown
T22176 10155-10158 VBP denotes are
T22175 10153-10154 -RRB- denotes )
T22174 10149-10153 CD denotes 0.05
T22173 10147-10148 FW denotes <
T22172 10145-10146 FW denotes p
T22171 10143-10144 SYM denotes =
T22170 10141-10142 SYM denotes *
T22169 10140-10141 -LRB- denotes (
T22168 10126-10139 NNS denotes significances
T22167 10122-10125 CC denotes and
T22166 10118-10121 NNP denotes SEM
T22165 10116-10117 CD denotes ±
T22164 10115-10116 CD denotes 1
T22163 10112-10114 TO denotes to
T22162 10106-10111 JJ denotes equal
T22161 10102-10105 VBN denotes set
T22160 10097-10101 VBD denotes were
T22159 10090-10096 NNS denotes levels
T22158 10082-10089 NN denotes control
T22157 10075-10081 NN denotes Medium
T22156 10073-10074 . denotes .
T22155 10072-10073 -RRB- denotes )
T22154 10071-10072 . denotes .
T22153 10067-10071 NN denotes calc
T22152 10064-10066 CD denotes -1
T22151 10057-10064 NNP denotes GP/TSST
T22150 10056-10057 -LRB- denotes (
T22149 10050-10055 NN denotes value
T22148 10038-10049 JJ denotes theoretical
T22147 10034-10037 DT denotes the
T22146 10030-10033 CC denotes and
T22145 10020-10029 NNS denotes compounds
T22144 10015-10019 DT denotes both
T22143 10012-10014 IN denotes of
T22142 9997-10011 NN denotes administration
T22141 9984-9996 JJ denotes simultaneous
T22140 9981-9983 IN denotes as
T22139 9976-9980 RB denotes well
T22138 9973-9975 RB denotes as
T22137 9971-9972 -RRB- denotes )
T22136 9969-9971 NN denotes ng
T22135 9965-9968 CD denotes 250
T22134 9964-9965 -LRB- denotes (
T22133 9954-9963 NN denotes treatment
T22132 9947-9953 CD denotes TSST-1
T22131 9944-9946 CC denotes or
T22130 9942-9943 -RRB- denotes )
T22129 9940-9942 NN denotes μg
T22128 9936-9939 CD denotes 100
T22127 9932-9935 CC denotes and
T22126 9930-9931 CD denotes 1
T22125 9929-9930 -LRB- denotes (
T22124 9926-9928 NNP denotes GP
T22123 9916-9925 VBG denotes following
T22122 9907-9915 NN denotes activity
T22121 9899-9906 JJ denotes binding
T22120 9890-9898 NNP denotes NFκB-DNA
T22119 9887-9889 IN denotes of
T22118 9872-9886 NN denotes representation
T22117 9862-9871 JJ denotes Schematic
T22116 9860-9861 . denotes .
T22115 9855-9860 VBN denotes shown
T22114 9852-9854 VBZ denotes is
T22113 9841-9851 NN denotes experiment
T22112 9826-9840 NN denotes representative
T22111 9824-9825 DT denotes a
T22110 9819-9823 IN denotes from
T22109 9805-9818 NN denotes autoradiogram
T22108 9802-9804 DT denotes An
T22107 9800-9801 . denotes .
T22106 9799-9800 NNP denotes C
T22105 9798-9799 CD denotes °
T22104 9796-9798 CD denotes 37
T22103 9793-9795 IN denotes at
T22102 9791-9792 NN denotes h
T22101 9789-9790 CD denotes 1
T22100 9785-9788 IN denotes for
T22099 9781-9784 NNP denotes LPS
T22098 9779-9780 NNP denotes +
T22097 9776-9778 NNP denotes GP
T22096 9772-9775 CC denotes and
T22095 9765-9771 NNP denotes TSST-1
T22094 9763-9764 NNP denotes +
T22093 9760-9762 NNP denotes GP
T22092 9758-9759 , denotes ,
T22091 9757-9758 -RRB- denotes )
T22090 9755-9757 NN denotes μg
T22089 9751-9754 CD denotes 100
T22088 9750-9751 -LRB- denotes (
T22087 9747-9749 NNP denotes GP
T22086 9745-9746 , denotes ,
T22085 9739-9745 NNP denotes TSST-1
T22084 9737-9738 , denotes ,
T22083 9734-9737 NNP denotes LPS
T22082 9732-9733 , denotes ,
T22081 9725-9732 NN denotes control
T22080 9718-9724 NN denotes medium
T22079 9713-9717 IN denotes with
T22078 9703-9712 VBN denotes incubated
T22077 9698-9702 VBD denotes were
T22076 9693-9697 NNP denotes PBMC
T22075 9687-9692 NNP denotes Human
T22074 9685-9686 . denotes .
T22073 9683-9685 NNP denotes GP
T22072 9682-9683 CD denotes /
T22071 9676-9682 CD denotes TSST-1
T22070 9673-9675 CC denotes or
T22069 9671-9672 , denotes ,
T22068 9669-9671 NNP denotes GP
T22067 9667-9668 , denotes ,
T22066 9661-9667 CD denotes TSST-1
T22065 9658-9660 TO denotes to
T22064 9649-9657 VBN denotes compared
T22063 9647-9648 , denotes ,
T22062 9641-9647 NNP denotes TSST-1
T22061 9639-9640 NNP denotes +
T22060 9636-9638 NNP denotes GP
T22059 9626-9635 VBG denotes following
T22058 9621-9625 NNP denotes NFκB
T22057 9618-9620 IN denotes of
T22056 9610-9617 JJ denotes binding
T22055 9606-9609 NNP denotes DNA
T22054 9596-9605 VBD denotes Decreased
T22053 9594-9595 , denotes ,
T22052 9593-9594 NNP denotes B
T22051 9591-9592 . denotes .
T22050 9590-9591 -RRB- denotes )
T22049 9589-9590 CD denotes 7
T22048 9587-9588 SYM denotes =
T22047 9585-9586 FW denotes n
T22046 9584-9585 -LRB- denotes (
T22045 9578-9583 VBN denotes shown
T22044 9575-9577 VBZ denotes is
T22043 9564-9574 NN denotes experiment
T22042 9549-9563 NN denotes representative
T22041 9547-9548 DT denotes a
T22040 9542-9546 IN denotes from
T22039 9528-9541 NN denotes autoradiogram
T22038 9525-9527 DT denotes An
T22037 9523-9524 . denotes .
T22036 9511-9523 RB denotes respectively
T22035 9509-9510 , denotes ,
T22034 9506-9509 NN denotes p50
T22033 9505-9506 : denotes -
T22032 9501-9504 CC denotes and
T22031 9478-9500 NN denotes NFκB-IL-8-DNA-anti-p65
T22030 9475-9477 IN denotes of
T22029 9464-9474 NN denotes supershift
T22028 9462-9463 DT denotes a
T22027 9452-9461 VBZ denotes indicates
T22026 9447-9451 NN denotes head
T22025 9442-9446 JJ denotes open
T22024 9438-9441 DT denotes the
T22023 9433-9437 IN denotes with
T22022 9427-9432 NNP denotes Arrow
T22021 9425-9426 . denotes .
T22020 9424-9425 -RRB- denotes )
T22019 9419-9424 NN denotes shift
T22018 9416-9418 DT denotes no
T22017 9415-9416 -LRB- denotes (
T22016 9409-9414 NN denotes probe
T22015 9404-9408 JJ denotes free
T22014 9401-9403 TO denotes to
T22013 9392-9400 VBN denotes compared
T22012 9384-9391 JJ denotes complex
T22011 9370-9383 NNP denotes NFκB-IL-8-DNA
T22010 9367-9369 CC denotes or
T22009 9356-9366 NNP denotes NFIL-6-DNA
T22008 9354-9355 , denotes ,
T22007 9346-9354 NNP denotes NFκB-DNA
T22006 9344-9345 , denotes ,
T22005 9336-9344 NNP denotes NFAT-DNA
T22004 9332-9335 DT denotes the
T22003 9329-9331 IN denotes of
T22002 9320-9328 NN denotes location
T22001 9308-9319 JJ denotes migrational
T22000 9299-9307 VBP denotes indicate
T21999 9294-9298 NN denotes head
T21998 9288-9293 JJ denotes black
T21997 9284-9287 DT denotes the
T21996 9279-9283 IN denotes with
T22726 10680-10682 IN denotes of
T22725 10671-10679 NNS denotes extracts
T22724 10663-10670 JJ denotes nuclear
T22723 10660-10662 IN denotes of
T22722 10651-10659 NN denotes staining
T22721 10647-10650 CC denotes and
T21995 9272-9278 NNS denotes Arrows
T21994 9270-9271 . denotes .
T21993 9269-9270 -RRB- denotes )
T21992 9268-9269 CD denotes 1
T21991 9262-9267 NNP denotes Table
T21990 9261-9262 -LRB- denotes (
T21989 9251-9260 NNS denotes promoters
T21988 9246-9250 NN denotes gene
T21987 9241-9245 NNP denotes IL-8
T21986 9237-9240 CC denotes and
T21985 9232-9236 NNP denotes IL-6
T21984 9230-9231 , denotes ,
T21983 9226-9230 NNP denotes TNFα
T21982 9224-9225 , denotes ,
T21981 9220-9224 NNP denotes IFNγ
T21980 9216-9219 DT denotes the
T21979 9213-9215 TO denotes to
T21978 9199-9212 JJ denotes corresponding
T21977 9193-9198 NN denotes probe
T21976 9177-9192 NN denotes oligonucleotide
T21975 9167-9176 JJ denotes NFκB-IL-8
T21974 9164-9166 CC denotes or
T21973 9157-9163 NNP denotes NFIL-6
T21972 9155-9156 , denotes ,
T21971 9151-9155 NNP denotes NFκB
T21970 9149-9150 , denotes ,
T22188 10203-10204 . denotes .
T22187 10202-10203 -RRB- denotes )
T22186 10201-10202 LS denotes 4
T20878 40017-40018 . denotes .
T20877 40015-40017 NNP denotes GP
T20876 40010-40014 IN denotes with
T20875 39999-40009 NN denotes incubation
T20874 39997-39998 NN denotes h
T20873 39994-39996 CD denotes 24
T20872 39988-39993 IN denotes after
T20871 39982-39987 NNP denotes ELISA
T20870 39979-39981 IN denotes by
T20869 39967-39978 JJ denotes supernatant
T20868 39963-39966 DT denotes the
T20867 39960-39962 IN denotes in
T20866 39951-39959 VBN denotes measured
T20865 39947-39950 VBD denotes was
T20864 39939-39946 NN denotes protein
T20863 39932-39938 NN denotes IL-1RA
T20862 39930-39931 . denotes .
T20861 39928-39930 NNP denotes GP
T20860 39923-39927 IN denotes with
T20859 39912-39922 NN denotes incubation
T20858 39910-39911 NN denotes h
T20857 39907-39909 CD denotes 18
T20856 39897-39906 VBG denotes following
T20855 39895-39896 -RRB- denotes )
T20854 39890-39895 NNP denotes GAPDH
T20853 39886-39889 IN denotes for
T20852 39879-39885 NNS denotes cycles
T20851 39876-39878 CD denotes 25
T20850 39874-39875 , denotes ,
T20849 39871-39874 NN denotes sec
T20848 39868-39870 CD denotes 45
T20847 39864-39867 IN denotes for
T20846 39862-39863 NNP denotes C
T20845 39861-39862 NN denotes °
T20844 39859-39861 CD denotes 72
T20843 39855-39858 CC denotes and
T20842 39851-39854 NN denotes sec
T20841 39848-39850 CD denotes 30
T20840 39844-39847 IN denotes for
T20839 39842-39843 NNP denotes C
T20838 39841-39842 NN denotes °
T20837 39839-39841 CD denotes 50
T20836 39837-39838 , denotes ,
T21969 9145-9149 NNP denotes NFAT
T21968 9133-9144 JJ denotes 32P-labeled
T21967 9131-9132 DT denotes a
T21966 9126-9130 IN denotes with
T21965 9116-9125 VBN denotes incubated
T21964 9111-9115 VBD denotes were
T21963 9102-9110 NNS denotes extracts
T21962 9094-9101 NNP denotes Nuclear
T21961 9091-9093 NNP denotes C.
T21960 9090-9091 CD denotes °
T21959 9088-9090 CD denotes 37
T21958 9085-9087 IN denotes at
T21957 9083-9084 NN denotes h
T21956 9081-9082 CD denotes 1
T21955 9077-9080 IN denotes for
T21954 9075-9076 -RRB- denotes )
T21953 9073-9075 NN denotes μg
T21952 9069-9072 CD denotes 100
T21951 9065-9068 CC denotes and
T21950 9063-9064 CD denotes 1
T21949 9062-9063 -LRB- denotes (
T21948 9059-9061 NNP denotes GP
T21947 9056-9058 CC denotes or
T21946 9048-9055 NN denotes control
T21945 9041-9047 NN denotes medium
T21944 9036-9040 IN denotes with
T21943 9026-9035 VBN denotes incubated
T21942 9021-9025 VBD denotes were
T21941 9016-9020 NNP denotes PBMC
T21940 9010-9015 NNP denotes Human
T21939 9008-9009 . denotes .
T21938 9002-9008 NNP denotes NFIL-6
T21937 8998-9001 CC denotes and
T21936 8993-8997 NNP denotes NFκB
T21935 8991-8992 , denotes ,
T21934 8987-8991 NNP denotes NFAT
T21933 8984-8986 IN denotes of
T21932 8976-8983 JJ denotes binding
T21931 8972-8975 NNP denotes DNA
T21930 8969-8971 TO denotes to
T21929 8965-8968 VBD denotes led
T21928 8962-8964 NNP denotes GP
T21927 8960-8961 , denotes ,
T21926 8959-8960 DT denotes A
T20835 39834-39837 NN denotes sec
T20834 39831-39833 CD denotes 30
T20833 39827-39830 IN denotes for
T20832 39825-39826 NNP denotes C
T20831 39824-39825 NN denotes °
T20830 39822-39824 CD denotes 94
T20829 39818-39821 CC denotes and
T20828 39811-39817 NN denotes IL-1RA
T20827 39807-39810 IN denotes for
T20826 39800-39806 NNS denotes cycles
T20825 39797-39799 CD denotes 25
T20824 39795-39796 , denotes ,
T20823 39792-39795 NN denotes sec
T20822 39789-39791 CD denotes 30
T20821 39787-39788 , denotes ,
T20820 39786-39787 NNP denotes C
T20819 39785-39786 NN denotes °
T20818 39783-39785 CD denotes 72
T20817 39781-39782 , denotes ,
T20816 39778-39781 NN denotes sec
T20815 39775-39777 CD denotes 30
T20814 39773-39774 , denotes ,
T20813 39772-39773 NNP denotes C
T20812 39771-39772 NN denotes °
T20811 39769-39771 CD denotes 55
T20810 39767-39768 , denotes ,
T20642 38954-38968 NNS denotes concentrations
T20641 38953-38954 -LRB- denotes (
T20640 38942-38952 NNS denotes substances
T20639 38932-38941 VBG denotes following
T20638 38928-38931 DT denotes the
T20637 38925-38927 IN denotes of
T20636 38920-38924 DT denotes each
T20635 38915-38919 IN denotes with
T20634 38913-38914 NN denotes h
T20633 38911-38912 CD denotes 1
T20632 38907-38910 IN denotes for
T20631 38897-38906 VBN denotes incubated
T20630 38892-38896 VBD denotes were
T20629 38887-38891 NNP denotes PBMC
T20628 38885-38886 , denotes ,
T20627 38877-38885 NN denotes promoter
T20626 38870-38876 NN denotes IL-1RA
T20625 38866-38869 DT denotes the
T20624 38863-38865 TO denotes to
T20623 38855-38862 NNS denotes factors
T20622 38841-38854 NN denotes transcription
T20621 38838-38840 IN denotes of
T20620 38830-38837 JJ denotes binding
T20619 38826-38829 CC denotes and
T20618 38812-38825 NN denotes translocation
T20617 38804-38811 VB denotes inhibit
T20616 38801-38803 TO denotes To
T20615 38793-38800 NNS denotes factors
T20614 38779-38792 NN denotes transcription
T20613 38776-38778 IN denotes of
T20612 38765-38775 NNP denotes Inhibition
T21348 40916-40917 . denotes .
T21347 40915-40916 -RRB- denotes )
T21346 40908-40915 NNP denotes Germany
T21345 40906-40907 , denotes ,
T21344 40899-40906 NNP denotes Erkrath
T21343 40897-40898 , denotes ,
T21342 40889-40897 NNP denotes Software
T21341 40881-40888 NNP denotes Science
T21340 40876-40880 NNP denotes SPSS
T21339 40874-40875 : denotes ;
T21338 40867-40874 NNS denotes Windows
T21337 40863-40866 IN denotes for
T21336 40858-40862 NNS denotes SPSS
T21335 40857-40858 -LRB- denotes (
T21334 40855-40856 , denotes ,
T21333 40854-40855 -RRB- denotes )
T21332 40842-40854 NN denotes distribution
T21331 40831-40841 JJ denotes non-normal
T21330 40830-40831 -LRB- denotes (
T21329 40825-40829 NN denotes test
T21328 40813-40824 NNP denotes Signed-Rank
T21327 40804-40812 NNP denotes Wilcoxon
T21326 40800-40803 DT denotes the
T21325 40797-40799 CC denotes or
T21324 40795-40796 -RRB- denotes )
T21323 40783-40795 NN denotes distribution
T21322 40776-40782 JJ denotes normal
T21321 40775-40776 -LRB- denotes (
T21320 40768-40774 JJS denotes t-test
T21319 40765-40767 POS denotes 's
T21318 40758-40765 NN denotes Student
T21317 40754-40757 DT denotes the
T21316 40748-40753 VBG denotes using
T21315 40739-40747 VBN denotes analysed
T21314 40734-40738 VBD denotes were
T21313 40732-40733 -RRB- denotes )
T21312 40731-40732 . denotes .
T21311 40727-40731 NN denotes calc
T21310 40724-40726 CD denotes -1
T21309 40717-40724 NNP denotes GP/TSST
T21308 40714-40716 VBZ denotes vs
T21307 40707-40713 NNP denotes TSST-1
T21306 40705-40706 NNP denotes +
T21305 40702-40704 NNP denotes GP
T21304 40694-40701 NN denotes example
T21303 40690-40693 IN denotes for
T21302 40689-40690 -LRB- denotes (
T21301 40682-40688 NNS denotes values
T21300 40670-40681 JJ denotes theoretical
T21299 40666-40669 CC denotes and
T21298 40661-40665 NNS denotes data
T21297 40648-40660 JJ denotes experimental
T21296 40640-40647 IN denotes between
T21295 40637-40639 IN denotes as
T21294 40632-40636 RB denotes well
T21293 40629-40631 RB denotes as
T21292 40627-40628 -RRB- denotes )
T21291 40624-40627 NNP denotes LPS
T21290 40621-40623 VBZ denotes vs
T21289 40618-40620 NNP denotes GP
T21288 40610-40617 NN denotes example
T21287 40606-40609 IN denotes for
T21286 40605-40606 -LRB- denotes (
T21285 40600-40604 NNS denotes data
T21284 40587-40599 JJ denotes experimental
T21283 40579-40586 IN denotes between
T21282 40567-40578 NNS denotes differences
T21281 40564-40566 IN denotes of
T21280 40550-40563 NNS denotes Significances
T21279 40548-40549 . denotes .
T21278 40547-40548 CD denotes 6
T21277 40543-40546 CC denotes and
T21276 40541-40542 , denotes ,
T21275 40540-40541 CD denotes 5
T21274 40538-40539 , denotes ,
T21273 40537-40538 CD denotes 4
T21272 40535-40536 , denotes ,
T21271 40534-40535 CD denotes 3
T21270 40532-40533 , denotes ,
T21269 40530-40532 NNP denotes 1B
T21268 40525-40529 NNP denotes Fig.
T21267 40520-40524 IN denotes into
T21266 40513-40519 NNS denotes values
T21265 40507-40512 DT denotes these
T21264 40501-40506 VBD denotes added
T21263 40497-40500 CC denotes and
T21262 40489-40496 NNS denotes effects
T21261 40478-40488 JJ denotes individual
T21260 40474-40477 DT denotes the
T21259 40471-40473 IN denotes of
T21258 40467-40470 NN denotes sum
T21257 40463-40466 DT denotes the
T21256 40452-40462 VBD denotes calculated
T21255 40449-40451 PRP denotes we
T21254 40447-40448 -RRB- denotes )
T21253 40446-40447 . denotes .
T21252 40442-40446 NN denotes calc
T21251 40439-40441 CD denotes -1
T21250 40432-40439 NNP denotes GP/TSST
T21249 40429-40431 VBZ denotes vs
T21248 40422-40428 NNP denotes TSST-1
T21247 40420-40421 NNP denotes +
T21246 40417-40419 NNP denotes GP
T21245 40409-40416 NN denotes example
T21244 40405-40408 IN denotes for
T21243 40404-40405 -LRB- denotes (
T21242 40398-40403 NN denotes value
T21241 40386-40397 JJ denotes theoretical
T21240 40384-40385 DT denotes a
T21239 40381-40383 TO denotes to
T21238 40376-40380 NNS denotes data
T21237 40363-40375 JJ denotes experimental
T21236 40355-40362 VB denotes compare
T21235 40352-40354 TO denotes To
T21234 40350-40351 . denotes .
T21233 40349-40350 -RRB- denotes )
T21232 40337-40349 NN denotes distribution
T21231 40326-40336 JJ denotes non-normal
T21230 40325-40326 -LRB- denotes (
T21229 40320-40324 NN denotes test
T21215 40234-40247 NNS denotes significances
T21214 40220-40233 JJ denotes corresponding
T21213 40216-40219 CC denotes and
T21212 40203-40215 NNS denotes coefficients
T21211 40191-40202 NN denotes Correlation
T21210 40189-40190 . denotes .
T21209 40178-40189 VBN denotes distributed
T21208 40169-40177 RB denotes normally
T21207 40164-40168 VBD denotes were
T21206 40156-40163 NNS denotes factors
T21205 40142-40155 NN denotes transcription
T21204 40139-40141 TO denotes to
T21203 40128-40138 NNS denotes activities
T21202 40120-40127 JJ denotes binding
T21201 40116-40119 CC denotes and
T21200 40108-40115 NNS denotes amounts
T21199 40099-40107 NN denotes cytokine
T21198 40091-40098 IN denotes whether
T21197 40089-40090 , denotes ,
T21196 40081-40089 VB denotes evaluate
T21195 40078-40080 TO denotes to
T21194 40073-40077 VBN denotes used
T21193 40069-40072 VBD denotes was
T21192 40064-40068 NN denotes test
T21191 40045-40063 NNP denotes Kolmogorow-Smirnov
T21190 40041-40044 DT denotes The
T21189 40032-40040 NN denotes analysis
T21188 40020-40031 NNP denotes Statistical
T21228 40311-40319 NNP denotes Spearman
T21227 40307-40310 DT denotes the
T21226 40304-40306 CC denotes or
T21225 40302-40303 -RRB- denotes )
T21224 40290-40302 NN denotes distribution
T21223 40283-40289 JJ denotes normal
T21222 40282-40283 -LRB- denotes (
T21221 40277-40281 NN denotes test
T21220 40269-40276 NNP denotes Pearson
T21219 40265-40268 DT denotes the
T21218 40262-40264 IN denotes by
T21217 40253-40261 VBN denotes analyzed
T21216 40248-40252 VBD denotes were
T20809 39764-39767 NN denotes sec
T20808 39761-39763 CD denotes 30
T20807 39759-39760 , denotes ,
T20806 39758-39759 NNP denotes C
T20805 39757-39758 NN denotes °
T20804 39755-39757 CD denotes 95
T20803 39754-39755 -LRB- denotes (
T20802 39752-39753 -RRB- denotes )
T20801 39746-39752 NNP denotes Biomol
T20800 39745-39746 -LRB- denotes (
T20799 39735-39744 NN denotes mastermix
T20798 39731-39734 NNP denotes PCR
T20797 39729-39730 '' denotes "
T20796 39724-39729 JJ denotes sweet
T20795 39723-39724 `` denotes "
T20794 39714-39722 NNP denotes HotStart
T20793 39712-39713 DT denotes a
T20792 39707-39711 IN denotes with
T20791 39703-39706 NNP denotes PCR
T20790 39700-39702 IN denotes by
T20789 39688-39699 NNS denotes transcripts
T20788 39682-39687 NNP denotes GAPDH
T20787 39678-39681 CC denotes and
T20786 39671-39677 NNP denotes IL-1RA
T20785 39667-39670 IN denotes for
T20784 39658-39666 VBD denotes analysed
T20783 39654-39657 CC denotes and
T20782 39652-39653 -RRB- denotes )
T20781 39646-39652 NNP denotes Biomol
T20780 39645-39646 -LRB- denotes (
T20779 39641-39644 NN denotes kit
T20778 39634-39640 NNP denotes Strand
T20777 39628-39633 NNP denotes First
T20776 39622-39627 NNP denotes Ready
T20775 39614-39621 NNP denotes Reactin
T20774 39609-39613 IN denotes with
T20773 39604-39608 NNP denotes cDNA
T20772 39599-39603 IN denotes into
T20771 39587-39598 VBN denotes transcribed
T20770 39583-39586 VBD denotes was
T20769 39579-39582 NNP denotes RNA
T20768 39569-39578 NN denotes messenger
T20767 39565-39568 CC denotes and
T20766 39563-39564 -RRB- denotes )
T20765 39556-39563 NNP denotes Germany
T20764 39554-39555 , denotes ,
T20763 39548-39554 NNP denotes Qiagen
T20762 39547-39548 -LRB- denotes (
T20761 39543-39546 NN denotes kit
T20760 39536-39542 NNP denotes RNeasy
T20759 39533-39535 DT denotes an
T20758 39528-39532 IN denotes with
T20757 39519-39527 VBN denotes isolated
T20756 39515-39518 VBD denotes was
T20755 39511-39514 NNP denotes RNA
T20754 39506-39510 NNP denotes PBMC
T20753 39504-39505 . denotes .
T20752 39496-39504 NN denotes promoter
T20751 39489-39495 NN denotes IL-1RA
T20750 39485-39488 DT denotes the
T20749 39478-39484 IN denotes within
T20748 39472-39477 NNS denotes sites
T20747 39464-39471 JJ denotes binding
T20746 39462-39463 -RRB- denotes )
T20745 39459-39462 NNP denotes TCT
T20744 39455-39458 NNP denotes CTA
T20701 39251-39252 . denotes .
T20700 39249-39251 NNP denotes GP
T20699 39244-39248 IN denotes with
T20698 39233-39243 NN denotes incubation
T20697 39230-39232 TO denotes to
T20696 39224-39229 RB denotes prior
T20695 39222-39223 -RRB- denotes )
T20694 39209-39222 NNP denotes Biotechnology
T20693 39204-39208 NNP denotes Cruz
T20692 39198-39203 NNP denotes Santa
T20691 39197-39198 -LRB- denotes (
T20690 39183-39196 NN denotes cycloheximide
T20689 39180-39182 NN denotes ml
T20688 39179-39180 NN denotes /
T20687 39177-39179 NN denotes μg
T20686 39174-39176 CD denotes 10
T20685 39172-39173 : denotes ;
T20684 39171-39172 -RRB- denotes )
T20683 39164-39171 NNP denotes Germany
T20682 39162-39163 , denotes ,
T20681 39157-39162 NNP denotes Soden
T20680 39153-39156 NNP denotes Bad
T20679 39151-39152 , denotes ,
T20678 39140-39151 NNP denotes Biosciences
T20677 39123-39139 NNP denotes Calbiochem-Merck
T20676 39122-39123 -LRB- denotes (
T20675 39120-39121 DT denotes A
T20674 39108-39119 NN denotes cyclosporin
T20673 39102-39107 JJ denotes ng/ml
T20672 39098-39101 CD denotes 400
T20671 39096-39097 : denotes ;
T20670 39095-39096 -RRB- denotes )
T20669 39088-39095 NNP denotes Germany
T20668 39086-39087 , denotes ,
T20667 39079-39086 NNP denotes Hamburg
T20666 39077-39078 , denotes ,
T20665 39071-39077 NNP denotes Biomol
T20664 39070-39071 -LRB- denotes (
T20663 39068-39069 , denotes ,
T20662 39067-39068 -RRB- denotes )
T20661 39032-39067 NN denotes dihydroxycinnamic-acid-phenyl-ester
T20660 39031-39032 : denotes -
T20659 39029-39031 SYM denotes ,4
T20658 39020-39029 JJ denotes caffeic-3
T20657 39019-39020 -LRB- denotes (
T20656 39014-39018 NNP denotes CAPE
T20655 39011-39013 IN denotes of
T20654 39008-39010 NN denotes ml
T20653 39007-39008 NN denotes /
T20652 39005-39007 NN denotes μg
T20651 39002-39004 CD denotes 50
T20650 39000-39001 : denotes :
T20649 38999-39000 -RRB- denotes )
T20648 38989-38999 NN denotes inhibition
T20647 38987-38988 NN denotes %
T20646 38985-38987 CD denotes 50
T20645 38980-38984 IN denotes upon
T20644 38974-38979 VBN denotes based
T20643 38969-38973 VBD denotes were
T20180 38762-38763 . denotes .
T20179 38752-38762 NNS denotes statistics
T20178 38748-38751 DT denotes the
T20177 38745-38747 IN denotes in
T20176 38736-38744 VBN denotes included
T20175 38732-38735 VBD denotes was
T20174 38724-38731 NN denotes release
T20173 38715-38723 NN denotes cytokine
T20172 38703-38714 JJ denotes spontaneous
T20171 38700-38702 DT denotes no
T20170 38692-38699 VBG denotes showing
T20169 38685-38691 NNS denotes donors
T20156 38615-38618 DT denotes the
T20155 38608-38614 IN denotes within
T20111 38381-38383 CD denotes 46
T20110 38380-38381 NNP denotes [
T20109 38370-38379 VBN denotes described
T20108 38359-38369 RB denotes previously
T20107 38356-38358 IN denotes as
T20106 38351-38355 VBN denotes done
T20105 38347-38350 VBD denotes was
T20104 38342-38346 NN denotes IL-1
T20103 38339-38341 IN denotes of
T20102 38327-38338 NN denotes bioactivity
T20101 38323-38326 DT denotes the
T20100 38319-38322 IN denotes for
T20099 38309-38318 NN denotes indicator
T20098 38306-38308 DT denotes an
T20097 38303-38305 IN denotes as
T20096 38298-38302 NN denotes IL-2
T20095 38295-38297 IN denotes of
T20094 38280-38294 NN denotes Quantification
T20093 38278-38279 . denotes .
T20092 38277-38278 NNP denotes ]
T20091 38275-38277 CD denotes 57
T20090 38274-38275 NNP denotes [
T20089 38264-38273 VBN denotes described
T20088 38253-38263 RB denotes previously
T20087 38250-38252 IN denotes as
T20086 38244-38249 NNP denotes ELISA
T20085 38241-38243 DT denotes an
T20058 38111-38117 NNP denotes Bender
T20057 38106-38110 IN denotes from
T20056 38100-38105 NNP denotes ELISA
T20055 38097-38099 DT denotes an
T20054 38091-38096 VBG denotes using
T20053 38080-38090 VBN denotes determined
T20052 38075-38079 VBD denotes were
T20051 38070-38074 NNP denotes IL-6
T20050 38066-38069 CC denotes and
T20049 38061-38065 NNP denotes IL-1
T20048 38059-38060 , denotes ,
T20047 38055-38059 NNP denotes TNFα
T20046 38053-38054 , denotes ,
T20045 38049-38053 NNP denotes IFNγ
T20044 38047-38048 . denotes .
T20043 38043-38047 RB denotes once
T20042 38038-38042 RB denotes only
T20041 38031-38037 VBN denotes thawed
T20040 38027-38030 CC denotes and
T20039 38022-38026 VBN denotes used
T20038 38016-38021 IN denotes until
T20037 38014-38015 NNP denotes C
T20036 38013-38014 CD denotes °
T20035 38009-38012 CD denotes -80
T20034 38006-38008 IN denotes at
T20033 37999-38005 VBD denotes stored
T20032 37995-37998 CC denotes and
T20031 37983-37994 NN denotes stimulation
T20030 37977-37982 IN denotes after
T20029 37971-37976 NNS denotes hours
T20028 37968-37970 CD denotes 48
T20027 37964-37967 CC denotes and
T20026 37961-37963 CD denotes 36
T20025 37959-37960 , denotes ,
T20024 37957-37959 CD denotes 30
T20023 37955-37956 , denotes ,
T20022 37953-37955 CD denotes 24
T20021 37951-37952 , denotes ,
T20020 37949-37951 CD denotes 18
T20019 37947-37948 , denotes ,
T20018 37945-37947 CD denotes 12
T20017 37943-37944 , denotes ,
T20016 37942-37943 CD denotes 9
T20015 37940-37941 , denotes ,
T20014 37939-37940 CD denotes 6
T20013 37937-37938 , denotes ,
T20012 37936-37937 CD denotes 3
T20011 37926-37935 VBN denotes harvested
T20010 37921-37925 VBD denotes were
T20009 37912-37920 NNS denotes cultures
T20008 37907-37911 NN denotes cell
T20007 37904-37906 IN denotes of
T20006 37891-37903 NNPS denotes Supernatants
T20005 37878-37890 NNS denotes measurements
T20004 37869-37877 NNP denotes Cytokine
T19639 37866-37867 . denotes .
T19638 37841-37845 NNP denotes Inc.
T19637 37828-37840 NNPS denotes Laboratories
T19636 37821-37827 NNP denotes Vector
T19635 37820-37821 -LRB- denotes (
T20154 38604-38607 DT denotes all
T20153 38599-38603 VBD denotes were
T20152 38591-38598 NNS denotes amounts
T20151 38582-38590 NNP denotes Cytokine
T20150 38580-38581 . denotes .
T20149 38579-38580 -RRB- denotes )
T20148 38573-38579 NNP denotes BioRad
T20147 38571-38572 , denotes ,
T20146 38565-38571 NNP denotes Reader
T20145 38554-38564 NNP denotes Microplate
T20144 38551-38553 CC denotes or
T20143 38543-38550 NNP denotes Austria
T20142 38541-38542 , denotes ,
T20141 38533-38541 NNP denotes Salzburg
T20140 38531-38532 , denotes ,
T20139 38524-38531 NNP denotes Labotec
T20138 38517-38523 NNP denotes Anthos
T20137 38516-38517 -LRB- denotes (
T20136 38509-38515 NN denotes reader
T20135 38503-38508 NN denotes plate
T20134 38497-38502 NNP denotes ELISA
T20133 38494-38496 DT denotes an
T20132 38488-38493 VBG denotes using
T20131 38477-38487 VBN denotes quantified
T20130 38472-38476 VBD denotes were
T20129 38462-38471 NNS denotes cytokines
T20128 38458-38461 DT denotes All
T20127 38456-38457 . denotes .
T20126 38447-38456 NNS denotes standards
T20125 38443-38446 DT denotes the
T20124 38439-38442 IN denotes for
T20123 38434-38438 VBN denotes used
T20122 38429-38433 DT denotes that
T20121 38426-38428 IN denotes as
T20120 38419-38425 NN denotes buffer
T20119 38414-38418 JJ denotes same
T20118 38410-38413 DT denotes the
T20117 38407-38409 IN denotes in
T20116 38399-38406 VBN denotes diluted
T20115 38394-38398 VBD denotes were
T20114 38386-38393 NNS denotes Samples
T20113 38384-38385 . denotes .
T20112 38383-38384 NNP denotes ]
T19634 37816-37819 NN denotes kit
T19633 37807-37815 VBG denotes staining
T19632 37805-37806 NN denotes ®
T19631 37795-37805 NNP denotes Vectastain
T19630 37791-37794 DT denotes the
T19629 37785-37790 VBG denotes using
T19628 37775-37784 VBN denotes developed
T19627 37771-37774 VBD denotes was
T19626 37766-37770 NN denotes blot
T19625 37762-37765 DT denotes The
T19624 37760-37761 . denotes .
T19623 37759-37760 -RRB- denotes )
T19622 37756-37759 NNP denotes BSA
T19621 37754-37755 NN denotes %
T19620 37749-37754 CD denotes PBS/1
T19619 37746-37748 IN denotes in
T19618 37740-37745 CD denotes 1:500
T19617 37739-37740 -LRB- denotes (
T19616 37730-37738 NN denotes antibody
T19615 37720-37729 JJ denotes secondary
T19614 37697-37719 JJ denotes phosphatase-conjugated
T19613 37688-37696 JJ denotes alkaline
T19612 37684-37687 DT denotes the
T19611 37679-37683 IN denotes with
T19610 37669-37678 VBN denotes incubated
T19609 37665-37668 CC denotes and
T19569 37457-37461 IN denotes onto
T19568 37449-37456 VBN denotes blotted
T19567 37444-37448 VBD denotes were
T19566 37435-37443 NNS denotes proteins
T19565 37427-37434 JJ denotes nuclear
T19564 37423-37426 DT denotes The
T19563 37421-37422 . denotes .
T19562 37414-37421 NN denotes sc-2022
T19561 37401-37413 NNP denotes AP-conjugate
T19560 37397-37400 NNP denotes IgG
T19559 37387-37396 JJ denotes anti-goat
T19558 37380-37386 JJ denotes donkey
T19557 37376-37379 CC denotes and
T19556 37374-37375 , denotes ,
T19555 37367-37374 JJ denotes sc-2007
T19554 37354-37366 NNP denotes AP-conjugate
T19553 37350-37353 NNP denotes IgG
T19552 37338-37349 JJ denotes anti-rabbit
T19551 37333-37337 VB denotes goat
T19550 37331-37332 : denotes :
T19549 37330-37331 -RRB- denotes )
T19548 37327-37330 VBP denotes dot
T19547 37326-37327 NN denotes /
T19546 37324-37326 NN denotes μg
T19545 37320-37323 CD denotes 0.8
T19544 37319-37320 -LRB- denotes (
T19543 37308-37318 NNS denotes antibodies
T19542 37298-37307 JJ denotes secondary
T19541 37296-37297 : denotes ;
T19540 37288-37296 NN denotes antisera
T19539 37283-37287 JJ denotes IgG1
T19538 37272-37282 JJ denotes polyclonal
T19537 37267-37271 NN denotes goat
T19536 37263-37266 CD denotes two
T19535 37261-37262 , denotes ,
T19534 37254-37261 JJ denotes sc-1149
T19533 37252-37253 -RRB- denotes )
T19532 37248-37252 NN denotes K-18
T19531 37247-37248 -LRB- denotes (
T19530 37235-37246 JJ denotes anti-NFATc1
T19529 37233-37234 , denotes ,
T19528 37226-37233 JJ denotes sc-1151
T19527 37224-37225 -RRB- denotes )
T19526 37220-37224 NN denotes M-20
T19525 37219-37220 -LRB- denotes (
T19524 37207-37218 JJ denotes anti-NFATc2
T19523 37205-37206 , denotes ,
T19522 37199-37205 JJ denotes sc-272
T19521 37197-37198 -RRB- denotes )
T19520 37193-37197 NNP denotes N466
T19519 37192-37193 -LRB- denotes (
T19518 37181-37191 JJ denotes anti-c-rel
T19517 37179-37180 , denotes ,
T19516 37170-37179 NN denotes antiserum
T19515 37165-37169 JJ denotes IgG1
T19514 37154-37164 NN denotes polyclonal
T19513 37147-37153 NN denotes rabbit
T19512 37145-37146 DT denotes a
T19511 37143-37144 , denotes ,
T19510 37137-37143 JJ denotes sc-848
T19509 37135-37136 -RRB- denotes )
T19508 37132-37135 CD denotes 447
T19507 37131-37132 -LRB- denotes (
T19506 37127-37130 NN denotes p52
T19505 37117-37126 JJ denotes anti-NFκB
T19504 37115-37116 , denotes ,
T19503 37109-37115 JJ denotes sc-109
T19502 37107-37108 -RRB- denotes )
T19501 37106-37107 NNP denotes A
T19500 37105-37106 -LRB- denotes (
T19499 37101-37104 NNS denotes p65
T19498 37091-37100 JJ denotes anti-NFκB
T19497 37089-37090 , denotes ,
T19496 37083-37089 JJ denotes sc-114
T19495 37081-37082 -RRB- denotes )
T19494 37078-37081 NNP denotes NLS
T19493 37077-37078 -LRB- denotes (
T19492 37073-37076 JJ denotes p50
T19491 37063-37072 JJ denotes anti-NFκB
T19490 37061-37062 : denotes :
T19489 37060-37061 -RRB- denotes )
T19488 37057-37060 VBP denotes dot
T19487 37056-37057 NN denotes /
T19486 37054-37056 NN denotes μg
T19485 37052-37053 CD denotes 1
T19484 37051-37052 -LRB- denotes (
T19483 37040-37050 NNS denotes antibodies
T19482 37032-37039 JJ denotes primary
T19481 37030-37031 : denotes ;
T19480 37016-37030 JJ denotes PMA-stimulated
T19479 37014-37015 , denotes ,
T19478 37007-37014 VB denotes extract
T19477 36999-37006 JJ denotes nuclear
T19476 36992-36998 NNP denotes Jurkat
T19475 36990-36991 : denotes ;
T19474 36981-36990 NN denotes sc-4030WB
T19473 36979-36980 -RRB- denotes )
T19472 36977-36979 NN denotes kD
T19471 36974-36976 CD denotes 61
T19470 36973-36974 -LRB- denotes (
T19469 36967-36972 NNP denotes c-Rel
T19468 36965-36966 , denotes ,
T19467 36956-36965 NN denotes sc-4095WB
T19466 36954-36955 -RRB- denotes )
T19465 36952-36954 NNP denotes kD
T19464 36949-36951 CD denotes 80
T19463 36948-36949 -LRB- denotes (
T19462 36944-36947 CD denotes p52
T19461 36939-36943 NNP denotes NFκB
T19460 36937-36938 : denotes :
T19459 36936-36937 -RRB- denotes )
T19458 36930-36936 NN denotes ng/dot
T19457 36927-36929 CD denotes 10
T19456 36926-36927 -LRB- denotes (
T19455 36917-36925 NNS denotes controls
T19454 36908-36916 JJ denotes positive
T19453 36906-36907 : denotes :
T19452 36905-36906 -RRB- denotes )
T19451 36898-36905 NNP denotes Germany
T19450 36896-36897 , denotes ,
T19449 36886-36896 NNP denotes Heidelberg
T19448 36884-36885 , denotes ,
T19447 36871-36884 NNP denotes Biotechnology
T19446 36866-36870 NNP denotes Cruz
T19445 36860-36865 NNP denotes Santa
T19444 36855-36859 IN denotes from
T19443 36851-36854 DT denotes all
T19442 36850-36851 -LRB- denotes (
T19441 36839-36849 NNS denotes antibodies
T19440 36835-36838 CC denotes and
T19439 36826-36834 NNS denotes controls
T19438 36817-36825 JJ denotes positive
T19437 36807-36816 VBG denotes following
T19436 36803-36806 DT denotes the
T19435 36798-36802 IN denotes with
T19434 36788-36797 VBN denotes performed
T19433 36783-36787 VBD denotes were
T19432 36781-36782 -RRB- denotes )
T19431 36774-36781 NNP denotes Germany
T19430 36772-36773 , denotes ,
T19429 36766-36772 NNP denotes Dassel
T19428 36764-36765 , denotes ,
T19427 36758-36764 NNP denotes Schüll
T19426 36756-36757 CC denotes &
T19425 36745-36755 NNP denotes Schleicher
T19424 36744-36745 -LRB- denotes (
T19423 36736-36743 NN denotes blotter
T19422 36732-36735 VBP denotes dot
T19421 36730-36731 PRP denotes I
T19420 36721-36729 NN denotes minifold
T19419 36717-36720 NNP denotes SNS
T19418 36710-36716 NNP denotes SRC96D
T19417 36708-36709 DT denotes a
T19416 36702-36707 VBG denotes using
T19415 36696-36701 NNS denotes blots
T19414 36692-36695 VBP denotes dot
T19413 36690-36691 , denotes ,
T19412 36686-36690 NNP denotes NFAT
T19411 36682-36685 CC denotes and
T19410 36677-36681 NNP denotes NFκB
T19409 36674-36676 TO denotes to
T19408 36666-36673 VBN denotes related
T19407 36661-36665 VBD denotes were
T19406 36652-36660 NNS denotes proteins
T19405 36644-36651 JJ denotes binding
T19404 36640-36643 NNP denotes DNA
T19403 36636-36639 DT denotes the
T19402 36628-36635 IN denotes whether
T19401 36618-36627 VB denotes determine
T19400 36615-36617 TO denotes To
T19399 36610-36614 NN denotes blot
T19398 36608-36609 -RRB- denotes )
T19397 36605-36608 NNP denotes Dot
T19396 36604-36605 -LRB- denotes (
T19395 36597-36603 NNP denotes Immuno
T19137 36594-36595 . denotes .
T19136 36587-36594 JJ denotes binding
T19135 36578-36586 JJ denotes specific
T19134 36573-36577 IN denotes with
T19133 36565-36572 VB denotes compete
T19132 36561-36564 RB denotes not
T19131 36557-36560 VBD denotes did
T19130 36551-36556 WDT denotes which
T19129 36549-36550 , denotes ,
T19128 36545-36549 VBN denotes used
T19127 36541-36544 VBD denotes was
T19126 36539-36540 -RRB- denotes )
T19125 36538-36539 CD denotes 1
T19124 36532-36537 NNP denotes Table
T19123 36530-36531 , denotes ,
T19122 36527-36530 NN denotes DNA
T19121 36517-36526 JJ denotes unrelated
T19120 36516-36517 -LRB- denotes (
T19119 36512-36515 NNP denotes DNA
T19118 36506-36511 NNP denotes Oct-1
T19117 36503-36505 IN denotes of
T19608 37659-37664 RB denotes again
T19607 37652-37658 VBD denotes washed
T19606 37650-37651 , denotes ,
T19605 37647-37650 NNP denotes BSA
T19604 37645-37646 NN denotes %
T19603 37640-37645 CD denotes PBS/1
T19602 37637-37639 IN denotes in
T19601 37630-37636 CD denotes 1:2000
T19600 37622-37629 VBN denotes diluted
T19599 37611-37621 NNS denotes antibodies
T19598 37603-37610 JJ denotes primary
T19597 37599-37602 DT denotes the
T19596 37594-37598 IN denotes with
T19595 37584-37593 JJ denotes overnight
T19594 37574-37583 VBN denotes incubated
T19593 37570-37573 VBD denotes was
T19592 37565-37569 NN denotes blot
T19591 37561-37564 DT denotes the
T19590 37559-37560 , denotes ,
T19589 37558-37559 -RRB- denotes )
T19588 37551-37558 NNP denotes Germany
T19587 37549-37550 , denotes ,
T19586 37538-37549 NNP denotes Deisenhofen
T19585 37536-37537 , denotes ,
T19584 37531-37536 NNP denotes Fluka
T19583 37530-37531 -LRB- denotes (
T19582 37526-37529 NNP denotes BSA
T19581 37524-37525 NN denotes %
T19580 37519-37524 CD denotes PBS/3
T19579 37514-37518 IN denotes with
T19578 37505-37513 VBG denotes blocking
T19577 37499-37504 IN denotes After
T19576 37497-37498 . denotes .
T19575 37496-37497 -RRB- denotes )
T19574 37489-37496 NNP denotes Bio-Rad
T19573 37488-37489 -LRB- denotes (
T19572 37479-37487 NN denotes membrane
T19571 37464-37478 JJ denotes nitrocellulose
T19570 37462-37463 DT denotes a
T19116 36496-36502 NN denotes excess
T19115 36490-36495 NN denotes molar
T19114 36482-36489 JJ denotes 30-fold
T19113 36480-36481 DT denotes a
T19112 36478-36479 , denotes ,
T19111 36469-36478 NNS denotes reactions
T19110 36456-36468 JJ denotes non-specific
T19109 36448-36455 VB denotes exclude
T19108 36445-36447 TO denotes To
T19107 36443-36444 . denotes .
T19106 36442-36443 -RRB- denotes )
T19105 36437-36442 VBN denotes shown
T19104 36433-36436 RB denotes not
T19103 36428-36432 NNS denotes data
T19102 36427-36428 -LRB- denotes (
T19101 36417-36426 VBN denotes performed
T19100 36412-36416 VBD denotes were
T19099 36403-36411 NN denotes antibody
T19098 36396-36402 CD denotes p65/50
T19097 36387-36395 VBN denotes combined
T19096 36385-36386 DT denotes a
T19095 36380-36384 IN denotes with
T19094 36375-36379 NNP denotes NFκB
T19093 36371-36374 IN denotes for
T19092 36364-36370 NNS denotes assays
T19091 36353-36363 JJ denotes supershift
T19067 36239-36250 NNS denotes experiments
T19066 36234-36238 JJ denotes such
T19065 36230-36233 IN denotes For
T19064 36228-36229 . denotes .
T19063 36220-36228 NNS denotes proteins
T19062 36212-36219 JJ denotes nuclear
T19061 36209-36211 TO denotes to
T19060 36201-36208 JJ denotes binding
T19059 36188-36200 JJ denotes non-specific
T19058 36180-36187 VB denotes prevent
T19057 36177-36179 TO denotes to
T19056 36171-36176 NN denotes order
T19055 36168-36170 IN denotes in
T19054 36164-36167 RP denotes out
T19053 36156-36163 VBN denotes carried
T19052 36151-36155 VBD denotes were
T19051 36149-36150 -RRB- denotes )
T19050 36144-36149 IN denotes above
T19049 36140-36143 VB denotes see
T19048 36139-36140 -LRB- denotes (
T19047 36133-36138 NNS denotes sites
T19046 36125-36132 JJ denotes binding
T19045 36116-36124 NN denotes promoter
T19044 36107-36115 NN denotes cytokine
T19043 36103-36106 DT denotes the
T19042 36100-36102 IN denotes of
T19041 36093-36099 NNS denotes oligos
T19040 36085-36092 VBN denotes mutated
T19039 36075-36084 JJ denotes unlabeled
T19038 36071-36074 CC denotes and
T19037 36063-36070 VBN denotes labeled
T19036 36058-36062 IN denotes with
T19035 36046-36057 NNS denotes experiments
T19034 36034-36045 NN denotes Competition
T19033 36032-36033 . denotes .
T19032 36024-36032 NNS denotes controls
T19031 36011-36023 JJ denotes unstimulated
T19030 36008-36010 IN denotes of
T19029 36002-36007 NNS denotes bands
T19028 35999-36001 TO denotes to
T19027 35988-35998 VBN denotes normalized
T19026 35984-35987 VBD denotes was
T19025 35978-35983 NNS denotes bands
T19024 35970-35977 VBN denotes shifted
T19023 35967-35969 IN denotes of
T19022 35957-35966 NN denotes intensity
T19021 35953-35956 DT denotes The
T19020 35951-35952 . denotes .
T19019 35950-35951 NNP denotes ]
T19018 35948-35950 CD denotes 56
T19017 35947-35948 NNP denotes [
T19016 35941-35946 NN denotes setup
T19015 35928-35940 JJ denotes experimental
T19014 35924-35927 PRP$ denotes our
T19013 35920-35923 IN denotes for
T19012 35911-35919 VBN denotes modified
T19011 35907-35910 CC denotes and
T19010 35905-35906 NNP denotes ]
T19009 35903-35905 CD denotes 27
T19008 35902-35903 NNP denotes [
T19007 35898-35901 FW denotes al.
T19006 35895-35897 FW denotes et
T19005 35889-35894 NNP denotes Trede
T19004 35886-35888 IN denotes by
T19003 35876-35885 VBN denotes described
T19002 35866-35875 NN denotes technique
T19001 35864-35865 DT denotes a
T19000 35861-35863 TO denotes to
T18999 35851-35860 VBG denotes according
T18998 35842-35850 JJ denotes prepared
T18997 35837-35841 VBD denotes were
T18996 35831-35836 NNS denotes PBMCs
T18995 35822-35830 JJ denotes purified
T18994 35819-35821 IN denotes of
T18993 35810-35818 NNS denotes extracts
T18992 35802-35809 NNP denotes Nuclear
T18991 35800-35801 -RRB- denotes )
T18990 35796-35800 NNP denotes EMSA
T18989 35795-35796 -LRB- denotes (
T18988 35788-35794 NNS denotes assays
T18987 35782-35787 NN denotes shift
T18986 35773-35781 NN denotes mobility
T18985 35757-35772 JJ denotes electrophoretic
T18984 35753-35756 CC denotes and
T18983 35744-35752 NNS denotes extracts
T18982 35736-35743 JJ denotes nuclear
T18981 35733-35735 IN denotes of
T18980 35721-35732 NNP denotes Preparation
T18714 35718-35719 . denotes .
T18713 35706-35718 NNS denotes instructions
T18712 35703-35705 POS denotes 's
T18711 35691-35703 NN denotes manufacturer
T18710 35687-35690 DT denotes the
T18709 35684-35686 TO denotes to
T18708 35674-35683 VBG denotes according
T18707 35672-35673 -RRB- denotes )
T18706 35663-35672 NNP denotes Pharmacia
T18705 35662-35663 -LRB- denotes (
T18704 35654-35661 NNP denotes Columns
T18703 35648-35653 NNP denotes Micro
T18702 35643-35647 NNP denotes G-50
T18701 35637-35642 NN denotes Quant
T18700 35631-35636 NNP denotes Probe
T18699 35625-35630 VBG denotes using
T18698 35614-35624 NN denotes filtration
T18697 35610-35613 NN denotes gel
T18696 35606-35609 IN denotes via
T18695 35597-35605 VBN denotes purified
T18694 35592-35596 VBD denotes were
T18693 35585-35591 NNS denotes oligos
T18692 35582-35584 NNS denotes ds
T18691 35578-35581 DT denotes the
T18690 35576-35577 , denotes ,
T18689 35566-35576 RB denotes Afterwards
T18688 35564-35565 . denotes .
T18687 35552-35564 RB denotes respectively
T18686 35550-35551 , denotes ,
T18685 35542-35550 NNS denotes proteins
T18684 35537-35541 NNP denotes NFκB
T18683 35533-35536 CC denotes and
T18682 35528-35532 NNP denotes NFAT
T18681 35525-35527 IN denotes of
T18680 35517-35524 JJ denotes binding
T18679 35513-35516 DT denotes the
T18678 35509-35512 IN denotes for
T18677 35501-35508 JJ denotes crucial
T18676 35498-35500 VB denotes be
T18675 35495-35497 TO denotes to
T18674 35490-35494 VBP denotes seem
T18673 35484-35489 WDT denotes which
T18672 35482-35483 , denotes ,
T18671 35473-35482 NNS denotes sequences
T18670 35468-35472 IN denotes with
T18669 35458-35467 VB denotes interfere
T18668 35455-35457 TO denotes to
T18667 35446-35454 VBN denotes reported
T18666 35441-35445 VBN denotes been
T18665 35436-35440 VBP denotes have
T18664 35434-35435 NNP denotes ]
T18663 35432-35434 CD denotes 55
T18662 35431-35432 NNP denotes [
T18661 35422-35430 NN denotes promoter
T18660 35417-35421 NNP denotes TNFα
T18659 35413-35416 DT denotes the
T18658 35410-35412 IN denotes of
T18657 35401-35409 NN denotes sequence
T18656 35391-35400 NN denotes consensus
T18655 35389-35390 NN denotes κ
T18654 35385-35388 DT denotes the
T18653 35382-35384 IN denotes in
T18652 35378-35381 CC denotes and
T18651 35376-35377 NNP denotes ]
T18650 35374-35376 CD denotes 29
T18649 35373-35374 NNP denotes [
T18648 35364-35372 NN denotes promoter
T18647 35359-35363 NNP denotes IFNγ
T18646 35355-35358 DT denotes the
T18645 35352-35354 IN denotes of
T18644 35347-35351 NN denotes site
T18643 35344-35346 NNP denotes P2
T18642 35340-35343 DT denotes the
T18641 35337-35339 IN denotes in
T18640 35327-35336 NNS denotes Mutations
T18639 35325-35326 . denotes .
T18638 35318-35325 NN denotes control
T18637 35307-35317 JJ denotes additional
T18636 35304-35306 DT denotes an
T18635 35301-35303 IN denotes as
T18634 35296-35300 VBN denotes used
T18633 35291-35295 VBD denotes were
T18632 35284-35290 NNS denotes oligos
T18631 35276-35283 VBN denotes mutated
T18630 35274-35275 , denotes ,
T18629 35268-35274 NNS denotes oligos
T18628 35264-35267 DT denotes the
T18627 35261-35263 IN denotes of
T18626 35249-35260 NN denotes specificity
T18625 35241-35248 JJ denotes binding
T19090 36351-36352 , denotes ,
T19089 36344-36351 JJ denotes binding
T19088 36341-36343 IN denotes of
T19087 36329-36340 NN denotes specificity
T19086 36325-36328 IN denotes For
T19085 36323-36324 . denotes .
T19084 36315-36323 NNS denotes extracts
T19083 36307-36314 JJ denotes nuclear
T19082 36303-36306 DT denotes the
T19081 36300-36302 TO denotes to
T19080 36294-36299 VBN denotes added
T19079 36290-36293 VBD denotes was
T19078 36283-36289 NNS denotes oligos
T19077 36273-36282 JJ denotes unlabeled
T19076 36270-36272 IN denotes of
T19075 36268-36269 -RRB- denotes )
T19074 36267-36268 NN denotes ×
T19073 36265-36267 CD denotes 50
T19072 36263-36264 CD denotes 5
T19071 36262-36263 -LRB- denotes (
T19070 36255-36261 JJ denotes excess
T19069 36252-36254 DT denotes an
T19068 36250-36251 , denotes ,
T18624 35237-35240 DT denotes the
T18623 35232-35236 VB denotes test
T18622 35229-35231 TO denotes To
T18621 35227-35228 . denotes .
T18620 35215-35227 NNS denotes instructions
T18619 35212-35214 POS denotes 's
T18618 35200-35212 NN denotes manufacturer
T18617 35196-35199 DT denotes the
T18616 35193-35195 TO denotes to
T18615 35183-35192 VBG denotes according
T18614 35181-35182 -RRB- denotes )
T18613 35174-35181 NNP denotes Germany
T18612 35172-35173 , denotes ,
T18611 35164-35172 NNP denotes Freiburg
T18610 35162-35163 , denotes ,
T18609 35159-35162 NNP denotes LKB
T18608 35149-35158 NNP denotes Pharmacia
T18607 35147-35148 , denotes ,
T18606 35144-35147 NNP denotes Kit
T18605 35140-35143 NNP denotes PNK
T18604 35139-35140 -LRB- denotes (
T18603 35135-35138 NNP denotes Kit
T18602 35101-35134 NNP denotes Ready-To-Go-Polynucleotide-Kinase
T18601 35097-35100 DT denotes the
T18600 35091-35096 VBG denotes using
T18599 35089-35090 -RRB- denotes )
T18595 35066-35067 , denotes ,
T18594 35058-35066 NNP denotes Amersham
T18593 35056-35057 , denotes ,
T18592 35049-35056 NNP denotes Ci/mmol
T18591 35043-35048 CD denotes 3,000
T18590 35042-35043 -LRB- denotes (
T18589 35034-35041 NNP denotes γ-P-ATP
T18588 35033-35034 '' denotes '
T18587 35032-35033 CD denotes 5
T18586 35027-35031 IN denotes with
T18585 35015-35026 JJ denotes 32P-labeled
T18584 35011-35014 CC denotes and
T18583 35009-35010 -RRB- denotes )
T18582 35002-35009 NNP denotes Germany
T18581 35000-35001 , denotes ,
T18580 34994-35000 NNP denotes Berlin
T18579 34992-34993 , denotes ,
T18578 34985-34992 NNP denotes Molbiol
T18577 34981-34984 NNP denotes TIB
T18576 34980-34981 -LRB- denotes (
T18575 34978-34979 , denotes ,
T18574 34977-34978 -RRB- denotes )
T18573 34976-34977 CD denotes 1
T18572 34970-34975 NNP denotes Table
T18571 34967-34969 IN denotes in
T18570 34955-34966 VBN denotes illustrated
T18569 34954-34955 -LRB- denotes (
T18568 34947-34953 NNS denotes oligos
T18567 34945-34946 -RRB- denotes )
T18566 34943-34945 NN denotes ss
T18565 34942-34943 -LRB- denotes (
T18564 34933-34941 VBN denotes stranded
T18563 34926-34932 JJ denotes single
T18562 34921-34925 IN denotes from
T18561 34909-34920 VBN denotes synthesised
T18560 34904-34908 VBD denotes were
T18559 34894-34903 NNS denotes promoters
T18558 34889-34893 NNP denotes IL-6
T18557 34885-34888 CC denotes and
T18556 34880-34884 NNP denotes IFNγ
T18555 34878-34879 , denotes ,
T18554 34874-34878 NNP denotes IL-8
T18553 34872-34873 , denotes ,
T18552 34868-34872 NNP denotes TNFα
T18551 34864-34867 DT denotes the
T18550 34859-34863 IN denotes from
T18549 34857-34858 -RRB- denotes )
T18548 34851-34857 NNS denotes oligos
T18547 34850-34851 -LRB- denotes (
T18546 34833-34849 NNS denotes oligonucleotides
T18545 34831-34832 -RRB- denotes )
T18544 34829-34831 NNS denotes ds
T18543 34828-34829 -LRB- denotes (
T18542 34812-34827 JJ denotes double-stranded
T18541 34798-34811 JJ denotes complementary
T18540 34794-34797 DT denotes The
T18539 34783-34793 NN denotes P-Labeling
T18538 34782-34783 : denotes -
T18537 34779-34782 SYM denotes -32
T18536 34778-34779 '' denotes '
T18535 34777-34778 CD denotes 5
T18534 34773-34776 CC denotes and
T18533 34771-34772 -RRB- denotes )
T18532 34765-34771 NNP denotes Oligos
T18531 34764-34765 -LRB- denotes (
T18530 34747-34763 NNS denotes Oligonucleotides
T18208 34741-34744 NNP denotes LPS
T18207 34737-34740 CC denotes and
T18206 34734-34736 NNP denotes GP
T18205 34731-34733 IN denotes of
T18204 34719-34730 NN denotes combination
T18203 34717-34718 DT denotes a
T18202 34712-34716 IN denotes with
T18201 34709-34711 CC denotes or
T18200 34702-34708 NNP denotes TSST-1
T18199 34698-34701 CC denotes and
T18198 34695-34697 NNP denotes GP
T18197 34692-34694 IN denotes of
T18196 34680-34691 NN denotes combination
T18195 34678-34679 DT denotes a
T18194 34673-34677 IN denotes with
T18193 34658-34672 RB denotes simultaneously
T18192 34645-34657 VBN denotes supplemented
T18191 34640-34644 VBD denotes were
T18190 34635-34639 NNP denotes PBMC
T18189 34633-34634 , denotes ,
T18188 34622-34633 NNS denotes experiments
T18187 34608-34621 JJ denotes costimulatory
T18186 34605-34607 IN denotes In
T18185 34603-34604 . denotes .
T18184 34602-34603 -RRB- denotes )
T18183 34595-34602 NNP denotes Germany
T18182 34593-34594 , denotes ,
T18181 34587-34593 NNP denotes Munich
T18180 34585-34586 , denotes ,
T18179 34580-34585 NNP denotes Sigma
T18178 34579-34580 -LRB- denotes (
T18177 34576-34578 NN denotes B4
T18176 34575-34576 : denotes :
T18175 34571-34575 CD denotes 0111
T18174 34562-34570 VBP denotes serotype
T18173 34557-34561 NNS denotes coli
T18172 34545-34556 NNP denotes Escherichia
T18171 34540-34544 IN denotes from
T18170 34536-34539 NNP denotes LPS
T18169 34526-34535 JJ denotes wild-type
T18168 34520-34525 NNS denotes cells
T18167 34513-34519 CD denotes ng/106
T18166 34509-34512 CD denotes 250
T18165 34504-34508 IN denotes with
T18164 34501-34503 CC denotes or
T18163 34499-34500 -RRB- denotes )
T18162 34496-34499 NNP denotes USA
T18161 34494-34495 , denotes ,
T18160 34492-34494 NNP denotes FL
T18159 34490-34491 , denotes ,
T18158 34482-34490 NNP denotes Sarasota
T18157 34480-34481 , denotes ,
T18156 34468-34480 NNPS denotes Technologies
T18155 34462-34467 NNP denotes Toxin
T18154 34461-34462 -LRB- denotes (
T18153 34454-34460 NNP denotes TSST-1
T18152 34448-34453 NNS denotes cells
T18151 34441-34447 CD denotes ng/106
T18150 34437-34440 CD denotes 250
T18149 34432-34436 IN denotes with
T18148 34430-34431 , denotes ,
T18147 34428-34430 NNP denotes GP
T18146 34425-34427 IN denotes of
T18145 34419-34424 NNS denotes cells
T18144 34415-34418 CD denotes 106
T18143 34411-34414 IN denotes per
T18142 34408-34410 NN denotes μg
T18141 34404-34407 CD denotes 100
T18140 34401-34403 CC denotes or
T18139 34399-34400 CD denotes 1
T18138 34394-34398 IN denotes with
T18137 34392-34393 -RRB- denotes )
T18136 34387-34392 NNP denotes ELISA
T18135 34386-34387 -LRB- denotes (
T18134 34384-34385 NN denotes h
T18133 34381-34383 CD denotes 48
T18132 34378-34380 TO denotes to
T18131 34376-34377 NN denotes h
T18130 34374-34375 CD denotes 0
T18129 34369-34373 IN denotes from
T18128 34366-34368 CC denotes or
T18127 34364-34365 -RRB- denotes )
T18126 34360-34364 NNP denotes EMSA
T18125 34359-34360 -LRB- denotes (
T18124 34357-34358 NN denotes h
T18123 34355-34356 CD denotes 1
T18122 34351-34354 IN denotes for
T18121 34340-34350 VBN denotes stimulated
T18120 34335-34339 VBD denotes were
T18119 34326-34334 NNS denotes Cultures
T18118 34324-34325 . denotes .
T18117 34323-34324 -RRB- denotes )
T18116 34316-34323 NNP denotes Germany
T18115 34314-34315 , denotes ,
T18114 34304-34314 NNP denotes Heidelberg
T18113 34302-34303 , denotes ,
T18112 34296-34302 NNP denotes Falcon
T18111 34295-34296 -LRB- denotes (
T18110 34288-34294 NNS denotes plates
T18109 34280-34287 NN denotes culture
T18108 34273-34279 JJ denotes 6-well
T18107 34260-34272 JJ denotes pyrogen-free
T18106 34252-34259 JJ denotes sterile
T18105 34249-34251 IN denotes in
T18104 34246-34248 NN denotes ml
T18103 34244-34245 CD denotes 4
T18102 34241-34243 IN denotes of
T18101 34234-34240 NN denotes volume
T18100 34232-34233 DT denotes a
T18099 34229-34231 IN denotes in
T18098 34220-34228 VBN denotes cultured
T18097 34215-34219 VBD denotes were
T18096 34210-34214 NNP denotes PBMC
T18095 34208-34209 , denotes ,
T18094 34199-34208 NNS denotes cytokines
T18093 34195-34198 CC denotes and
T18092 34187-34194 NNS denotes factors
T18091 34173-34186 NN denotes transcription
T18090 34170-34172 IN denotes of
T18089 34160-34169 NN denotes induction
T18088 34156-34159 IN denotes For
T18087 34145-34155 NNS denotes conditions
T18086 34133-34144 NN denotes Stimulation
T18598 35082-35089 NNP denotes Germany
T18597 35080-35081 , denotes ,
T18596 35068-35080 NNP denotes Braunschweig
T17922 34130-34131 . denotes .
T17921 34129-34130 -RRB- denotes )
T17920 34117-34129 NNP denotes BioWhittaker
T17919 34116-34117 -LRB- denotes (
T17918 34104-34115 NNP denotes L-glutamine
T17917 34101-34103 NNP denotes mM
T17916 34097-34100 CD denotes 200
T17915 34095-34096 NN denotes %
T17914 34094-34095 CD denotes 1
T17913 34090-34093 CC denotes and
T17912 34088-34089 , denotes ,
T17911 34087-34088 -RRB- denotes )
T17910 34085-34087 NN denotes ml
T17909 34084-34085 NN denotes /
T17908 34082-34084 NN denotes μg
T17907 34076-34081 CD denotes 10000
T17906 34075-34076 -LRB- denotes (
T17905 34062-34074 NN denotes streptomycin
T17904 34060-34061 NN denotes %
T17903 34059-34060 CD denotes 1
T17902 34057-34058 , denotes ,
T17901 34056-34057 -RRB- denotes )
T17900 34052-34056 NNP denotes U/ml
T17899 34046-34051 CD denotes 10000
T17898 34045-34046 -LRB- denotes (
T17897 34034-34044 NN denotes penicillin
T17896 34032-34033 NN denotes %
T17895 34031-34032 CD denotes 1
T17894 34029-34030 , denotes ,
T17893 34028-34029 -RRB- denotes )
T17892 34021-34028 NNP denotes Germany
T17891 34019-34020 , denotes ,
T17890 34010-34019 NNP denotes Karlsruhe
T17889 34008-34009 , denotes ,
T17888 33998-34008 NNP denotes Invitrogen
T17887 33996-33997 , denotes ,
T17886 33989-33996 NNP denotes low-LPS
T17885 33987-33988 , denotes ,
T17884 33984-33987 NNP denotes FCS
T17883 33983-33984 -LRB- denotes (
T17882 33977-33982 NN denotes serum
T17881 33972-33976 NN denotes calf
T17880 33966-33971 JJ denotes fetal
T17879 33949-33965 JJ denotes heat-inactivated
T17878 33947-33948 NN denotes %
T17877 33945-33947 CD denotes 10
T17876 33934-33944 VBG denotes containing
T17875 33932-33933 , denotes ,
T17874 33931-33932 -RRB- denotes )
T17873 33923-33931 JJ denotes LPS-free
T17872 33921-33922 , denotes ,
T17871 33914-33921 NNP denotes Germany
T17870 33912-33913 , denotes ,
T17869 33902-33912 NNP denotes Heidelberg
T17868 33900-33901 , denotes ,
T17867 33888-33900 NNP denotes BioWhittaker
T17866 33887-33888 -LRB- denotes (
T17865 33880-33886 NN denotes medium
T17864 33875-33879 CD denotes 1640
T17863 33870-33874 NNP denotes RPMI
T17862 33867-33869 IN denotes in
T17861 33865-33866 -RRB- denotes )
T17860 33856-33865 NN denotes cytometry
T17859 33851-33855 NN denotes flow
T17858 33847-33850 IN denotes for
T17857 33846-33847 -LRB- denotes (
T17856 33837-33845 NN denotes cells/ml
T17855 33833-33836 CD denotes 106
T17854 33831-33832 CD denotes ×
T17853 33829-33830 CD denotes 1
T17852 33826-33828 CC denotes or
T17851 33824-33825 -RRB- denotes )
T17850 33818-33824 NNS denotes shifts
T17849 33814-33817 NN denotes gel
T17848 33810-33813 IN denotes for
T17847 33809-33810 -LRB- denotes (
T17846 33802-33808 CD denotes 106/ml
T17845 33800-33801 NN denotes ×
T17844 33798-33799 CD denotes 5
T17843 33795-33797 CC denotes or
T17842 33793-33794 -RRB- denotes )
T17841 33781-33793 NNS denotes measurements
T17840 33775-33780 NNP denotes ELISA
T17839 33771-33774 IN denotes for
T17838 33770-33771 -LRB- denotes (
T17837 33761-33769 NN denotes cells/ml
T17836 33757-33760 CD denotes 106
T17835 33755-33756 CD denotes ×
T17834 33753-33754 CD denotes 3
T17833 33750-33752 IN denotes of
T17832 33736-33749 NN denotes concentration
T17831 33730-33735 JJ denotes final
T17830 33728-33729 DT denotes a
T17829 33725-33727 IN denotes at
T17828 33716-33724 VBN denotes cultured
T17827 33711-33715 VBD denotes were
T17826 33706-33710 NNP denotes PBMC
T17825 33704-33705 , denotes ,
T17824 33695-33704 NN denotes isolation
T17823 33685-33694 VBG denotes Following
T17822 33683-33684 . denotes .
T17821 33682-33683 NNP denotes ]
T17820 33677-33682 CD denotes 54,55
T17819 33676-33677 NNP denotes [
T17818 33667-33675 NN denotes gradient
T17817 33665-33666 -RRB- denotes )
T17816 33658-33665 NNP denotes Germany
T17815 33656-33657 , denotes ,
T17814 33650-33656 NNP denotes Berlin
T17813 33648-33649 , denotes ,
T17812 33640-33648 NNP denotes Biochrom
T17811 33639-33640 -LRB- denotes (
T17810 33624-33638 NNP denotes Ficoll-Hypaque
T17809 33622-33623 DT denotes a
T17808 33617-33621 IN denotes over
T17807 33607-33616 VBN denotes separated
T17806 33602-33606 VBD denotes were
T17805 33596-33601 NNS denotes coats
T17804 33590-33595 JJ denotes buffy
T17803 33586-33589 DT denotes The
T17802 33584-33585 . denotes .
T17801 33577-33584 NNP denotes Luebeck
T17800 33574-33576 IN denotes of
T17799 33563-33573 NNP denotes University
T17798 33559-33562 DT denotes the
T17797 33556-33558 IN denotes of
T17796 33546-33555 NN denotes committee
T17795 33539-33545 NNS denotes ethics
T17794 33535-33538 DT denotes the
T17793 33532-33534 IN denotes of
T17792 33523-33531 NN denotes approval
T17611 33387-33388 . denotes .
T17610 33376-33387 NNS denotes 3-D-glucans
T17609 33375-33376 NN denotes →
T17608 33372-33375 JJ denotes β-1
T17607 33369-33371 TO denotes to
T17606 33361-33368 VB denotes respond
T17605 33357-33360 RB denotes not
T17604 33352-33356 VBZ denotes does
T17603 33348-33351 CC denotes but
T17602 33338-33347 NN denotes endotoxin
T17601 33334-33337 IN denotes for
T17600 33325-33333 JJ denotes specific
T17599 33322-33324 VBZ denotes is
T17598 33316-33321 WDT denotes which
T17597 33314-33315 , denotes ,
T17596 33313-33314 -RRB- denotes )
T17595 33308-33313 NNP denotes Japan
T17594 33306-33307 , denotes ,
T17593 33301-33306 NNP denotes Tokyo
T17592 33299-33300 , denotes ,
T17591 33290-33299 NNP denotes Seigakaku
T17590 33289-33290 -LRB- denotes (
T17589 33283-33288 NN denotes assay
T17588 33273-33282 NNP denotes Endospecy
T17587 33269-33272 DT denotes the
T17586 33264-33268 IN denotes with
T17585 33250-33263 NN denotes contamination
T17584 33240-33249 NN denotes endotoxin
T17583 33236-33239 IN denotes for
T17582 33227-33235 VBD denotes screened
T17581 33223-33226 CC denotes and
T17580 33221-33222 -RRB- denotes )
T17579 33219-33221 NN denotes μm
T17578 33215-33218 CD denotes 0.2
T17577 33214-33215 -LRB- denotes (
T17576 33196-33213 VBN denotes filter-sterilized
T17418 32966-32967 . denotes .
T17417 32965-32966 NNP denotes ]
T17416 32960-32965 CD denotes 52,53
T17415 32959-32960 NNP denotes [
T17414 32953-32958 NN denotes ratio
T17413 32946-32952 NN denotes IL-1RA
T17412 32945-32946 NN denotes /
T17411 32940-32945 NN denotes IL-1β
T17410 32927-32939 VBN denotes dysregulated
T17409 32925-32926 DT denotes a
T17408 32920-32924 IN denotes with
T17407 32909-32919 RB denotes especially
T17406 32907-32908 , denotes ,
T17405 32897-32907 NNS denotes conditions
T17404 32880-32896 JJ denotes pro-inflammatory
T17403 32877-32879 IN denotes in
T17402 32867-32876 NN denotes phosphate
T17401 32860-32866 JJ denotes glucan
T17400 32857-32859 IN denotes by
T17399 32848-32856 VBN denotes mediated
T17398 32840-32847 NNS denotes effects
T17397 32829-32839 JJ denotes protective
T17359 32630-32640 VBN denotes identified
T17358 32624-32629 RB denotes newly
T17357 32620-32623 CC denotes and
T17356 32614-32619 VBN denotes known
T17355 32606-32613 JJ denotes various
T17354 32603-32605 TO denotes to
T17353 32595-32602 JJ denotes binding
T17352 32588-32594 NN denotes factor
T17351 32574-32587 NN denotes transcription
T17350 32571-32573 IN denotes of
T17349 32561-32570 NN denotes interplay
T17348 32553-32560 JJ denotes complex
T17347 32548-32552 RB denotes very
T17346 32546-32547 DT denotes a
T17345 32541-32545 IN denotes into
T17344 32532-32540 NNS denotes insights
T17343 32528-32531 JJ denotes new
T17342 32518-32527 VBD denotes generated
T17341 32513-32517 RB denotes also
T17340 32505-32512 NNS denotes results
T17339 32501-32504 PRP$ denotes Our
T17338 32499-32500 . denotes .
T17337 32491-32499 NN denotes reaction
T17336 32473-32490 JJ denotes anti-inflammatory
T17297 32209-32216 NN denotes summary
T17296 32206-32208 IN denotes In
T16328 32192-32193 . denotes .
T16327 32191-32192 NNP denotes ]
T16326 32189-32191 CD denotes 51
T16325 32188-32189 NNP denotes [
T16324 32182-32187 NNS denotes parts
T16323 32178-32181 DT denotes all
T16322 32175-32177 IN denotes in
T16321 32164-32174 JJ denotes equivalent
T16320 32160-32163 RB denotes not
T16319 32156-32159 VBP denotes are
T16318 32150-32155 WDT denotes which
T16317 32142-32149 NNS denotes signals
T16316 32139-32141 IN denotes of
T16315 32128-32138 NN denotes suggestive
T16314 32126-32127 , denotes ,
T16313 32115-32126 NN denotes combination
T16312 32112-32114 IN denotes in
T16311 32096-32111 RB denotes synergistically
T16310 32090-32095 VBD denotes acted
T16309 32086-32089 CC denotes and
T16308 32077-32085 NNS denotes proteins
T16307 32054-32076 JJ denotes mechanisms/DNA-binding
T16306 32044-32053 JJ denotes different
T16305 32036-32043 IN denotes through
T16304 32031-32035 NN denotes gene
T16303 32024-32030 NNP denotes IL-1RA
T16302 32020-32023 DT denotes the
T16301 32010-32019 VBN denotes activated
T16300 31996-32009 JJ denotes peptidoglycan
T16299 31992-31995 CC denotes and
T16298 31988-31991 NNP denotes LPS
T16297 31986-31987 , denotes ,
T16296 31983-31986 NNP denotes PRR
T16295 31975-31982 JJ denotes similar
T16294 31972-31974 IN denotes of
T16293 31968-31971 NN denotes use
T16292 31964-31967 DT denotes the
T16291 31956-31963 IN denotes despite
T16290 31951-31955 IN denotes that
T16289 31943-31950 VBG denotes showing
T16288 31937-31942 NN denotes study
T16287 31929-31936 DT denotes another
T16286 31926-31928 IN denotes by
T16285 31916-31925 VBN denotes supported
T16284 31913-31915 VB denotes be
T16283 31909-31912 MD denotes may
T16282 31904-31908 NN denotes idea
T16281 31899-31903 DT denotes This
T16280 31897-31898 . denotes .
T16279 31896-31897 -RRB- denotes )
T16278 31887-31896 VBG denotes signaling
T16277 31880-31886 NN denotes kinase
T16276 31862-31879 JJ denotes mitogen-activated
T16275 31861-31862 -LRB- denotes (
T16274 31857-31860 NNP denotes LPS
T16273 31853-31856 CC denotes and
T16272 31851-31852 -RRB- denotes )
T16271 31847-31851 NNP denotes PI3K
T16270 31846-31847 -LRB- denotes (
T16269 31843-31845 NNP denotes GP
T16268 31835-31842 IN denotes between
T16267 31825-31834 VBG denotes signaling
T16266 31822-31824 IN denotes in
T16265 31811-31821 NN denotes difference
T16264 31809-31810 DT denotes a
T16263 31805-31808 IN denotes for
T16262 31793-31804 NN denotes explanation
T16261 31790-31792 DT denotes an
T16260 31784-31789 VB denotes offer
T16259 31780-31783 MD denotes may
T16258 31774-31779 WDT denotes which
T16257 31772-31773 , denotes ,
T16256 31771-31772 NNP denotes ]
T16255 31769-31771 CD denotes 50
T16254 31768-31769 NNP denotes [
T16253 31763-31767 NNP denotes PI3K
T16252 31759-31762 IN denotes via
T16251 31753-31758 NN denotes place
T16250 31748-31752 VB denotes take
T16249 31743-31747 RB denotes also
T16248 31739-31742 MD denotes can
T16247 31734-31738 NNP denotes NFκB
T16246 31731-31733 IN denotes of
T16245 31720-31730 NNP denotes Activation
T16244 31718-31719 . denotes .
T16243 31717-31718 NNP denotes ]
T16242 31715-31717 CD denotes 49
T16241 31714-31715 NNP denotes [
T16240 31708-31713 NNS denotes cells
T16239 31706-31707 NNP denotes T
T16238 31703-31705 IN denotes in
T16237 31698-31702 NNP denotes NFAT
T16236 31695-31697 IN denotes of
T16235 31684-31694 NN denotes activation
T16234 31680-31683 DT denotes the
T16233 31677-31679 IN denotes in
T16232 31668-31676 VBN denotes involved
T16231 31665-31667 VB denotes be
T16230 31662-31664 TO denotes to
T16229 31653-31661 VBN denotes reported
T16228 31648-31652 VBN denotes been
T16227 31644-31647 VBZ denotes has
T16226 31639-31643 NNP denotes PI3K
T16225 31635-31638 IN denotes via
T16224 31625-31634 VBG denotes Signaling
T16223 31623-31624 . denotes .
T16222 31622-31623 NNP denotes ]
T16221 31620-31622 CD denotes 48
T16220 31619-31620 NNP denotes [
T16219 31608-31618 NN denotes production
T16218 31602-31607 JJ denotes IL-1β
T16217 31598-31601 RB denotes not
T16216 31594-31597 CC denotes but
T16215 31586-31593 NN denotes sIL-1RA
T16214 31577-31585 VBZ denotes controls
T16213 31565-31576 RB denotes selectively
T16212 31557-31564 NN denotes pathway
T16211 31552-31556 NNP denotes PI3K
T16210 31548-31551 DT denotes the
T16209 31537-31547 NNS denotes leukocytes
T16208 31518-31536 JJ denotes septic/LPS-adapted
T16207 31515-31517 IN denotes in
T16206 31510-31514 IN denotes that
T16205 31497-31509 VBN denotes demonstrated
T16204 31492-31496 VBN denotes been
T16203 31488-31491 VBZ denotes has
T16202 31485-31487 PRP denotes It
T16201 31483-31484 . denotes .
T16200 31482-31483 NNP denotes ]
T16199 31477-31482 CD denotes 22,37
T16198 31476-31477 NNP denotes [
T16197 31466-31475 NN denotes treatment
T16196 31463-31465 NNP denotes GP
T16195 31460-31462 IN denotes by
T16194 31450-31459 VBN denotes sustained
T16193 31447-31449 VB denotes be
T16192 31443-31446 MD denotes may
T16191 31436-31442 NN denotes effect
T16190 31431-31435 DT denotes this
T16189 31427-31430 CC denotes and
T16188 31425-31426 NNP denotes ]
T16187 31423-31425 CD denotes 44
T16186 31422-31423 NNP denotes [
T16185 31412-31421 VBG denotes signaling
T16184 31408-31411 IN denotes for
T16183 31400-31407 NN denotes pathway
T16182 31395-31399 NNP denotes PI3K
T16181 31391-31394 DT denotes the
T16180 31387-31390 VB denotes use
T16179 31384-31386 TO denotes to
T16178 31378-31383 VBN denotes shown
T16177 31373-31377 VBN denotes been
T16176 31369-31372 VBZ denotes has
T16175 31362-31368 CD denotes TSST-1
T15898 29899-29901 IN denotes in
T15897 29897-29898 -RRB- denotes )
T15896 29893-29897 CD denotes -280
T15895 29889-29892 CC denotes and
T15894 29884-29888 CD denotes -266
T15893 29883-29884 -LRB- denotes (
T15892 29878-29882 NN denotes site
T15891 29868-29877 NN denotes consensus
T15890 29863-29867 NNP denotes NFκB
T15889 29859-29862 JJ denotes new
T15888 29855-29858 DT denotes the
T15887 29852-29854 IN denotes of
T15886 29843-29851 NN denotes location
T15885 29839-29842 DT denotes the
T15884 29831-29838 IN denotes Despite
T15883 29829-29830 . denotes .
T15882 29828-29829 NNP denotes ]
T15881 29823-29828 CD denotes 41,42
T15880 29822-29823 NNP denotes [
T15879 29814-29821 JJ denotes binding
T15878 29811-29813 IN denotes in
T15877 29799-29810 NNS denotes differences
T15876 29796-29798 TO denotes to
T15875 29788-29795 VBG denotes leading
T15874 29779-29787 RB denotes probably
T15873 29777-29778 , denotes ,
T15872 29776-29777 -RRB- denotes )
T15871 29775-29776 CD denotes 1
T15870 29769-29774 NNP denotes Table
T15869 29765-29768 VBP denotes see
T15868 29763-29764 , denotes ,
T15867 29758-29763 NN denotes motif
T15866 29753-29757 NNP denotes TNFα
T15865 29749-29752 DT denotes the
T15864 29746-29748 IN denotes in
T15863 29744-29745 NNP denotes C
T15862 29734-29743 JJ denotes conserved
T15861 29730-29733 DT denotes the
T15860 29727-29729 IN denotes of
T15859 29719-29726 RB denotes instead
T15858 29716-29718 CD denotes 10
T15857 29707-29715 NN denotes position
T15856 29704-29706 IN denotes on
T15855 29702-29703 NN denotes T
T15854 29700-29701 DT denotes a
T15853 29691-29699 VBZ denotes contains
T15852 29685-29690 NN denotes motif
T15851 29678-29684 NNP denotes IL-1RA
T15850 29674-29677 DT denotes the
T15849 29668-29673 NNP denotes NFκB3
T15848 29664-29667 IN denotes for
T15847 29663-29664 -LRB- denotes (
T15846 29654-29662 NN denotes promoter
T15845 29647-29653 NN denotes IL-1RA
T15844 29643-29646 DT denotes the
T15843 29639-29642 CC denotes and
T15842 29634-29638 NNP denotes TNFα
T15841 29630-29633 DT denotes the
T15840 29622-29629 IN denotes between
T15839 29616-29621 NN denotes motif
T15838 29608-29615 JJ denotes binding
T15837 29603-29607 NNP denotes NFκB
T15836 29593-29602 JJ denotes decameric
T15835 29589-29592 DT denotes the
T15834 29582-29588 IN denotes within
T15833 29580-29581 -RRB- denotes )
T15832 29578-29580 CD denotes 10
T15831 29576-29577 , denotes ,
T15830 29575-29576 CD denotes 3
T15829 29573-29574 , denotes ,
T15828 29572-29573 CD denotes 2
T15827 29570-29571 , denotes ,
T15826 29569-29570 CD denotes 1
T15825 29568-29569 # denotes #
T15824 29567-29568 -LRB- denotes (
T15823 29555-29566 NNS denotes nucleotides
T15822 29545-29554 VBN denotes conserved
T15821 29542-29544 CC denotes or
T15820 29533-29541 NNS denotes subunits
T15819 29528-29532 NNP denotes NFκB
T15818 29521-29527 DT denotes either
T15817 29518-29520 IN denotes in
T15816 29506-29517 NNS denotes differences
T15815 29503-29505 IN denotes by
T15814 29493-29502 VBN denotes explained
T15813 29490-29492 VB denotes be
T15812 29484-29489 MD denotes could
T15811 29479-29483 NNS denotes data
T15810 29465-29478 JJ denotes contradictory
T15809 29455-29464 RB denotes seemingly
T15808 29449-29454 DT denotes These
T15807 29447-29448 . denotes .
T15806 29439-29447 NN denotes promoter
T15805 29432-29438 NN denotes IL-1RA
T15804 29428-29431 DT denotes the
T15803 29425-29427 IN denotes of
T15802 29419-29424 NNS denotes sites
T15801 29409-29418 NN denotes consensus
T15800 29404-29408 NNP denotes NFκB
T15799 29400-29403 CC denotes and
T15798 29394-29399 NNP denotes NFκB3
T15797 29391-29393 TO denotes to
T15796 29377-29390 NN denotes up-regulation
T15795 29374-29376 DT denotes an
T15794 29370-29373 VBD denotes was
T15793 29364-29369 EX denotes there
T15792 29362-29363 , denotes ,
T15791 29354-29362 NN denotes promoter
T15790 29349-29353 NNP denotes TNFα
T15004 24818-24819 NNP denotes ]
T15789 29345-29348 DT denotes the
T15788 29342-29344 IN denotes of
T15787 29336-29341 NNS denotes sites
T15786 29333-29335 TO denotes to
T15785 29325-29332 JJ denotes binding
T15784 29320-29324 NN denotes NFκB
T15783 29305-29319 JJ denotes TSST-1-induced
T15782 29301-29304 DT denotes the
T15781 29297-29300 CC denotes and
T15780 29295-29296 : denotes -
T15779 29292-29295 NNP denotes LPS
T15778 29288-29291 DT denotes the
T15777 29285-29287 IN denotes of
T15776 29269-29284 NN denotes down-regulation
T15775 29257-29268 JJ denotes GP-mediated
T15774 29255-29256 DT denotes a
T15773 29246-29254 VBD denotes observed
T15772 29243-29245 PRP denotes we
T15771 29237-29242 IN denotes while
T15770 29235-29236 , denotes ,
T15769 29233-29235 RB denotes So
T15768 29231-29232 . denotes .
T15767 29229-29231 NNP denotes GP
T15766 29226-29228 IN denotes by
T15765 29216-29225 VBN denotes increased
T15764 29213-29215 VB denotes be
T15763 29210-29212 TO denotes to
T15762 29203-29209 VBD denotes seemed
T15761 29198-29202 NN denotes site
T15760 29188-29197 NN denotes consensus
T15759 29183-29187 NNP denotes NFκB
T15758 29179-29182 JJ denotes new
T15757 29175-29178 DT denotes the
T15756 29172-29174 TO denotes to
T15755 29164-29171 JJ denotes binding
T15754 29149-29163 JJ denotes TSST-1-induced
T15753 29145-29148 DT denotes the
T15752 29141-29144 CC denotes and
T15751 29135-29140 NNP denotes NFκB3
T15750 29131-29134 DT denotes the
T15749 29128-29130 TO denotes to
T15748 29120-29127 JJ denotes binding
T15747 29108-29119 JJ denotes LPS-induced
T15746 29104-29107 CC denotes and
T15745 29102-29103 : denotes -
T15744 29096-29102 NN denotes TSST-1
T15743 29092-29095 DT denotes the
T15742 29085-29091 RB denotes mostly
T15741 29083-29084 , denotes ,
T15740 29075-29083 NN denotes promoter
T15739 29068-29074 NN denotes IL-1RA
T15738 29064-29067 DT denotes the
T15737 29059-29063 IN denotes from
T15736 29053-29058 NNS denotes sites
T15735 29048-29052 NNP denotes NFκB
T15734 29039-29047 VBD denotes examined
T15733 29034-29038 CD denotes four
T15732 29030-29033 DT denotes the
T15731 29027-29029 IN denotes Of
T15730 29025-29026 . denotes .
T15729 29024-29025 -RRB- denotes )
T15728 29018-29024 NN denotes detail
T15727 29015-29017 IN denotes in
T15726 29009-29014 VBN denotes shown
T15725 29005-29008 RB denotes not
T15724 29000-29004 NNS denotes data
T15723 28998-28999 : denotes ;
T15722 28994-28998 CD denotes 0.01
T15721 28992-28993 NN denotes <
T15720 28990-28991 VB denotes p
T15719 28988-28989 : denotes ;
T15718 28983-28988 CD denotes -0.88
T15717 28981-28982 SYM denotes =
T15716 28979-28980 NN denotes r
T15715 28978-28979 -LRB- denotes (
T15714 28967-28977 NN denotes production
T15713 28960-28966 NN denotes IL-1RA
T15712 28945-28959 JJ denotes TSST-1-induced
T15711 28941-28944 DT denotes the
T15710 28938-28940 IN denotes of
T15709 28926-28937 NN denotes enhancement
T15708 28914-28925 JJ denotes GP-mediated
T15707 28910-28913 DT denotes the
T15706 28905-28909 IN denotes with
T15705 28894-28904 VBN denotes correlated
T15704 28883-28893 RB denotes negatively
T15703 28874-28882 NN denotes promoter
T15702 28869-28873 NNP denotes TNFα
T15701 28865-28868 DT denotes the
T15700 28860-28864 IN denotes from
T15699 28854-28859 NNS denotes sites
T15698 28851-28853 TO denotes to
T15697 28846-28850 NNP denotes NFκB
T15696 28843-28845 IN denotes of
T15695 28835-28842 JJ denotes binding
T15694 28820-28834 JJ denotes TSST-1-induced
T15693 28816-28819 DT denotes the
T15692 28811-28815 IN denotes that
T15691 28805-28810 VBD denotes found
T15690 28802-28804 PRP denotes we
T15689 28800-28801 , denotes ,
T15688 28789-28800 RB denotes Accordingly
T15687 28787-28788 . denotes .
T15686 28779-28787 NN denotes promoter
T15685 28774-28778 NNP denotes IFNγ
T15684 28771-28773 CC denotes or
T15683 28766-28770 NNP denotes IL-6
T15003 24816-24818 CD denotes 17
T16174 31360-31361 . denotes .
T16173 31359-31360 NNP denotes ]
T16172 31354-31359 CD denotes 43-45
T16171 31353-31354 NNP denotes [
T16170 31346-31352 NNP denotes TSST-1
T16169 31342-31345 CC denotes and
T16168 31338-31341 NNP denotes LPS
T16167 31330-31337 IN denotes between
T16166 31321-31329 NNS denotes pathways
T16165 31311-31320 VBG denotes signaling
T16164 31308-31310 IN denotes in
T16163 31296-31307 NNS denotes differences
T16162 31287-31295 JJ denotes balanced
T16161 31276-31286 RB denotes delicately
T16160 31273-31275 TO denotes to
T16159 31262-31272 VBN denotes attributed
T16158 31259-31261 VB denotes be
T16157 31255-31258 MD denotes may
T16156 31253-31254 , denotes ,
T16155 31248-31253 NN denotes study
T16154 31243-31247 DT denotes this
T16153 31240-31242 IN denotes in
T16152 31231-31239 VBD denotes observed
T16151 31222-31230 NN denotes response
T16150 31215-31221 JJ denotes immune
T16149 31203-31214 JJ denotes LPS-induced
T16148 31199-31202 DT denotes the
T16147 31196-31198 IN denotes on
T16146 31193-31195 NNP denotes GP
T16145 31190-31192 IN denotes of
T16144 31182-31189 NNS denotes effects
T16143 31171-31181 JJ denotes modulating
T16142 31164-31170 JJR denotes weaker
T16141 31160-31163 DT denotes The
T16140 31158-31159 . denotes .
T16139 31157-31158 -RRB- denotes )
T16138 31151-31157 NN denotes detail
T16137 31148-31150 IN denotes in
T16136 31142-31147 VBN denotes shown
T16135 31138-31141 RB denotes not
T16134 31133-31137 NNS denotes data
T16133 31132-31133 -LRB- denotes (
T16132 31126-31131 NNS denotes cells
T16131 31121-31125 NN denotes EL-4
T16130 31114-31120 NN denotes murine
T16129 31111-31113 IN denotes of
T16128 31100-31110 NN denotes production
T16127 31095-31099 NN denotes IL-2
T16126 31080-31094 JJ denotes IL-1-dependent
T16125 31078-31079 , denotes ,
T16124 31064-31078 JJ denotes TSST-1-induced
T16123 31060-31063 DT denotes the
T16122 31052-31059 VBD denotes reduced
T16121 31049-31051 NNP denotes GP
T16120 31047-31048 , denotes ,
T16119 31041-31047 RB denotes Indeed
T16118 31039-31040 . denotes .
T16117 31033-31039 NN denotes system
T16116 31029-31032 PRP$ denotes our
T16115 31026-31028 IN denotes in
T16114 31014-31025 VBN denotes inactivated
T16113 31011-31013 VBZ denotes is
T16112 30999-31010 NN denotes bioactivity
T16111 30993-30998 JJ denotes IL-1β
T16110 30988-30992 DT denotes that
T16109 30981-30987 VB denotes assume
T16108 30978-30980 TO denotes to
T16107 30965-30977 JJ denotes unreasonable
T16106 30961-30964 RB denotes not
T16105 30958-30960 VBZ denotes is
T16104 30955-30957 PRP denotes it
T16103 30953-30954 , denotes ,
T16102 30949-30953 CD denotes 0.01
T16101 30944-30948 IN denotes than
T16100 30939-30943 JJR denotes less
T16099 30929-30938 RB denotes partially
T16098 30926-30928 VBZ denotes is
T16097 30919-30925 NNP denotes TSST-1
T16096 30917-30918 NNP denotes +
T16095 30914-30916 NNP denotes GP
T16088 30879-30880 , denotes ,
T16087 30875-30879 NN denotes fact
T16086 30872-30874 IN denotes in
T16085 30870-30871 , denotes ,
T16084 30865-30870 IN denotes Since
T16083 30863-30864 . denotes .
T16082 30862-30863 NNP denotes ]
T16081 30857-30862 CD denotes 46,47
T16080 30856-30857 NNP denotes [
T16079 30851-30855 NNP denotes IL-1
T16078 30848-30850 IN denotes of
T16077 30840-30847 NNS denotes effects
T16076 30829-30839 JJ denotes biological
T16075 30825-30828 DT denotes the
T16074 30817-30824 VB denotes control
T16073 30811-30816 MD denotes might
T16072 30805-30810 NN denotes IL-1β
T16071 30800-30804 IN denotes over
T16070 30793-30799 NN denotes IL-1RA
T16069 30790-30792 IN denotes of
T16068 30783-30789 NN denotes excess
T16067 30775-30782 JJ denotes 100fold
T16066 30773-30774 DT denotes a
T16065 30767-30772 NN denotes vitro
T16064 30764-30766 IN denotes in
T16063 30759-30763 IN denotes that
T16062 30748-30758 VBN denotes postulated
T16061 30743-30747 VBN denotes been
T16060 30739-30742 VBZ denotes has
T16059 30736-30738 PRP denotes it
T16058 30734-30735 , denotes ,
T16057 30727-30734 NN denotes context
T16056 30722-30726 DT denotes this
T16055 30719-30721 IN denotes In
T16054 30717-30718 . denotes .
T16053 30716-30717 -RRB- denotes )
T16052 30715-30716 CD denotes 6
T16051 30710-30714 NNP denotes Fig.
T16050 30709-30710 -LRB- denotes (
T16049 30702-30708 NNP denotes TSST-1
T16048 30700-30701 NNP denotes +
T16047 30697-30699 NNP denotes GP
T16046 30687-30696 VBG denotes following
T16045 30681-30686 NN denotes ratio
T16044 30674-30680 NN denotes IL-1RA
T16043 30673-30674 NN denotes /
T16042 30668-30673 JJ denotes IL-1β
T16041 30664-30667 DT denotes the
T16040 30661-30663 IN denotes of
T16039 30652-30660 NN denotes decrease
T16038 30648-30651 DT denotes the
T16037 30645-30647 IN denotes by
T16036 30635-30644 VBN denotes reflected
T16035 30631-30634 VBD denotes was
T16034 30617-30630 NN denotes transcription
T16033 30614-30616 IN denotes of
T16032 30603-30613 NN denotes activation
T16031 30590-30602 JJ denotes GP-modulated
T16030 30585-30589 DT denotes this
T16029 30580-30584 IN denotes that
T16028 30574-30579 VBP denotes think
T16027 30571-30573 PRP denotes We
T16026 30569-30570 . denotes .
T16025 30559-30569 NN denotes production
T16024 30552-30558 NN denotes IL-1RA
T16023 30537-30551 JJ denotes TSST-1-induced
T16022 30533-30536 DT denotes the
T16021 30530-30532 IN denotes of
T16020 30516-30529 NN denotes up-regulation
T16019 30504-30515 JJ denotes synergistic
T16018 30500-30503 DT denotes the
T16017 30492-30499 VB denotes explain
T16016 30488-30491 MD denotes may
T16015 30483-30487 NN denotes site
T16014 30474-30482 NNP denotes NFATP2/3
T16013 30468-30473 NN denotes novel
T16012 30464-30467 DT denotes the
T16011 30461-30463 TO denotes to
T16010 30458-30460 IN denotes as
T16009 30453-30457 RB denotes well
T16008 30450-30452 RB denotes as
T16007 30448-30449 NNP denotes ]
T16006 30446-30448 CD denotes 32
T16005 30445-30446 NNP denotes [
T16004 30440-30444 NN denotes site
T16003 30433-30439 NNP denotes NFIL-6
T16002 30429-30432 DT denotes the
T16001 30427-30428 , denotes ,
T16000 30423-30427 NN denotes site
T15999 30413-30422 NN denotes consensus
T15998 30408-30412 NNP denotes NFκB
T15997 30404-30407 CC denotes and
T15996 30398-30403 NNP denotes NFκB3
T15995 30394-30397 JJ denotes new
T15994 30390-30393 DT denotes the
T15993 30387-30389 TO denotes to
T15992 30379-30386 JJ denotes binding
T15991 30364-30378 JJ denotes TSST-1-induced
T15990 30361-30363 IN denotes in
T15989 30352-30360 NN denotes increase
T15988 30339-30351 JJ denotes GP-modulated
T15987 30335-30338 DT denotes The
T15986 30333-30334 . denotes .
T15985 30332-30333 NNP denotes ]
T15984 30330-30332 CD denotes 30
T15983 30329-30330 NNP denotes [
T15982 30321-30328 NN denotes element
T15981 30310-30320 NN denotes inhibitory
T15980 30300-30309 VBN denotes described
T15979 30289-30299 JJ denotes previoulsy
T15978 30285-30288 DT denotes the
T15977 30282-30284 IN denotes of
T15976 30277-30281 NN denotes part
T15975 30275-30276 DT denotes a
T15974 30269-30274 JJS denotes least
T15973 30266-30268 IN denotes at
T15972 30256-30265 VB denotes represent
T15971 30246-30255 RB denotes therefore
T15970 30242-30245 MD denotes may
T15969 30237-30241 NN denotes site
T15968 30232-30236 DT denotes this
T15967 30230-30231 , denotes ,
T15966 30223-30230 NN denotes opinion
T15965 30219-30222 PRP$ denotes our
T15964 30216-30218 IN denotes In
T15963 30214-30215 . denotes .
T15962 30212-30214 NNP denotes GP
T15961 30209-30211 IN denotes by
T15960 30201-30208 VBN denotes altered
T15959 30198-30200 VB denotes be
T15958 30194-30197 RB denotes not
T15957 30188-30193 MD denotes could
T15956 30182-30187 WDT denotes which
T15955 30180-30181 , denotes ,
T15954 30173-30180 JJ denotes binding
T15953 30158-30172 JJ denotes TSST-1-induced
T15952 30154-30157 CC denotes and
T15951 30152-30153 : denotes -
T15950 30149-30152 NNP denotes LPS
T15949 30145-30148 DT denotes the
T15948 30142-30144 IN denotes of
T15947 30125-30141 NNS denotes down-regulations
T15946 30111-30124 VBG denotes demonstrating
T15945 30109-30110 , denotes ,
T15944 30102-30109 NN denotes element
T15943 30091-30101 JJ denotes inhibitory
T15942 30087-30090 DT denotes the
T15941 30084-30086 IN denotes of
T15940 30080-30083 NN denotes end
T15939 30076-30079 DT denotes the
T15938 30068-30075 IN denotes towards
T15937 30066-30067 -RRB- denotes )
T15936 30062-30066 CD denotes -302
T15935 30058-30061 CC denotes and
T15934 30053-30057 CD denotes -288
T15933 30052-30053 -LRB- denotes (
T15932 30047-30051 NN denotes site
T15931 30045-30046 CD denotes 3
T15930 30044-30045 NN denotes /
T15929 30039-30044 NNP denotes NFκB2
T15928 30028-30038 JJ denotes inhibitory
T15927 30025-30027 DT denotes an
T15926 30019-30024 VBD denotes found
T15925 30016-30018 PRP denotes we
T15924 30014-30015 , denotes ,
T15923 30010-30014 NN denotes side
T15922 30004-30009 JJ denotes other
T15921 30000-30003 DT denotes the
T15920 29997-29999 IN denotes On
T15919 29995-29996 . denotes .
T15918 29985-29995 NN denotes inhibition
T15917 29982-29984 DT denotes no
T15916 29973-29981 VBD denotes observed
T15915 29970-29972 PRP denotes we
T15914 29968-29969 , denotes ,
T15913 29967-29968 NNP denotes ]
T15912 29965-29967 CD denotes 30
T15911 29964-29965 NNP denotes [
T15910 29955-29963 NN denotes promoter
T15909 29948-29954 NN denotes IL-1RA
T15908 29944-29947 DT denotes the
T15907 29941-29943 IN denotes of
T15906 29939-29940 -RRB- denotes )
T15905 29935-29939 CD denotes -294
T15904 29931-29934 CC denotes and
T15903 29926-29930 CD denotes -250
T15902 29925-29926 -LRB- denotes (
T15901 29917-29924 NN denotes element
T15900 29906-29916 JJ denotes inhibitory
T15899 29902-29905 DT denotes the
T16094 30904-30913 VBG denotes following
T16093 30898-30903 NN denotes ratio
T16092 30891-30897 NN denotes IL-1RA
T16091 30890-30891 NN denotes /
T16090 30885-30890 JJ denotes IL-1β
T16089 30881-30884 DT denotes the
T15682 28764-28765 , denotes ,
T15681 28759-28764 NNP denotes IL-1β
T15680 28757-28758 , denotes ,
T15679 28753-28757 NNP denotes TNFα
T15678 28749-28752 DT denotes the
T15677 28746-28748 IN denotes of
T15676 28738-28745 RB denotes instead
T15675 28729-28737 NN denotes promoter
T15674 28722-28728 NN denotes IL-1RA
T15673 28718-28721 CC denotes and
T15672 28713-28717 NN denotes IL-8
T15671 28709-28712 DT denotes the
T15670 28702-28708 IN denotes within
T15669 28696-28701 NNS denotes sites
T15668 28688-28695 JJ denotes unknown
T15667 28684-28687 RB denotes now
T15666 28681-28683 TO denotes to
T15665 28678-28680 RB denotes up
T15664 28674-28677 CC denotes and
T15663 28668-28673 VBN denotes known
T15662 28665-28667 TO denotes to
T15661 28660-28664 NNP denotes NFAT
T15660 28656-28659 CC denotes and
T15659 28649-28655 NNP denotes NFIL-6
T15658 28647-28648 , denotes ,
T15657 28643-28647 NNP denotes NFκB
T15656 28640-28642 IN denotes of
T15655 28632-28639 JJ denotes binding
T15654 28624-28631 JJ denotes induced
T15653 28617-28623 CD denotes TSST-1
T15652 28613-28616 DT denotes the
T15651 28610-28612 IN denotes of
T15650 28598-28609 NNS denotes modulations
T15649 28586-28597 JJ denotes GP-mediated
T15648 28583-28585 IN denotes by
T15647 28576-28582 VBN denotes caused
T15646 28573-28575 VB denotes be
T15645 28569-28572 MD denotes may
T15644 28562-28568 NN denotes change
T15643 28557-28561 DT denotes this
T15642 28555-28556 , denotes ,
T15641 28551-28555 NN denotes part
T15640 28548-28550 IN denotes In
T15639 28546-28547 . denotes .
T15638 28540-28546 NN denotes IL-1RA
T15637 28537-28539 IN denotes of
T15636 28523-28536 NN denotes up-regulation
T15635 28511-28522 JJ denotes synergistic
T15634 28509-28510 DT denotes a
T15633 28505-28508 VBD denotes was
T15632 28499-28504 EX denotes there
T15631 28494-28498 NN denotes time
T15630 28489-28493 JJ denotes same
T15629 28485-28488 DT denotes the
T15628 28482-28484 IN denotes at
T15627 28480-28481 , denotes ,
T15626 28476-28480 NN denotes IL-6
T15625 28472-28475 CC denotes and
T15624 28466-28471 NN denotes IL-1β
T15623 28463-28465 IN denotes of
T15622 28447-28462 NN denotes down-regulation
T15621 28443-28446 IN denotes via
T15620 28435-28442 NN denotes profile
T15619 28417-28434 JJ denotes anti-inflammatory
T15618 28414-28416 DT denotes an
T15617 28411-28413 TO denotes to
T15616 28406-28410 JJ denotes pro-
T15615 28404-28405 DT denotes a
T15614 28399-28403 IN denotes from
T15613 28393-28398 NN denotes ratio
T15612 28386-28392 NN denotes IL-1RA
T15611 28385-28386 NN denotes /
T15610 28380-28385 JJ denotes IL-1β
T15609 28365-28379 JJ denotes TSST-1-induced
T15608 28361-28364 DT denotes the
T15607 28353-28360 VBD denotes altered
T15606 28350-28352 NNP denotes GP
T15605 28348-28349 , denotes ,
T15604 28342-28348 RB denotes Mainly
T15603 28340-28341 . denotes .
T15602 28339-28340 NNP denotes ]
T15601 28334-28339 CD denotes 21-24
T15600 28333-28334 NNP denotes [
T15599 28320-28332 NN denotes inflammation
T15598 28316-28319 CC denotes and
T15597 28309-28315 NN denotes sepsis
T15596 28306-28308 IN denotes of
T15595 28299-28305 NNS denotes models
T15594 28292-28298 NN denotes murine
T15593 28289-28291 IN denotes in
T15592 28281-28288 NNS denotes effects
T15591 28277-28280 DT denotes the
T15590 28274-28276 TO denotes to
T15589 28266-28273 JJ denotes similar
T15588 28264-28265 , denotes ,
T15587 28255-28264 NNS denotes reactions
T15586 28248-28254 JJ denotes immune
T15585 28231-28247 JJ denotes pro-inflammatory
T15584 28225-28230 PRP$ denotes their
T15583 28213-28224 VBD denotes ameliorated
T15582 28210-28212 NNP denotes GP
T15581 28208-28209 , denotes ,
T15580 28207-28208 -RRB- denotes )
T15579 28201-28207 NNP denotes TSST-1
T15578 28198-28200 CC denotes or
T15577 28194-28197 NNP denotes LPS
T15576 28193-28194 -LRB- denotes (
T15575 28185-28192 NNS denotes stimuli
T15574 28179-28184 JJ denotes other
T15573 28176-28178 IN denotes of
T15572 28167-28175 NN denotes presence
T15571 28163-28166 DT denotes the
T15570 28160-28162 IN denotes in
T15569 28158-28159 , denotes ,
T15568 28154-28158 IN denotes that
T15567 28148-28153 VBD denotes found
T15566 28145-28147 PRP denotes we
T15565 28143-28144 , denotes ,
T15564 28141-28143 NNP denotes GP
T15563 28138-28140 IN denotes by
T15562 28130-28137 VBN denotes induced
T15561 28124-28129 NN denotes panel
T15560 28115-28123 NN denotes cytokine
T15559 28106-28114 JJ denotes specific
T15558 28102-28105 DT denotes the
T15557 28097-28101 IN denotes than
T15556 28088-28096 JJ denotes relevant
T15555 28083-28087 RBR denotes more
T15554 28078-28082 RB denotes even
T15553 28066-28077 RB denotes Potentially
T15552 27823-27824 . denotes .
T15551 27817-27823 NN denotes attack
T15550 27807-27816 JJ denotes microbial
T15549 27798-27806 JJ denotes possible
T15548 27796-27797 DT denotes a
T15547 27788-27795 IN denotes against
T15546 27777-27787 NNS denotes mechanisms
T15545 27767-27776 JJ denotes defensive
T15544 27758-27766 VBG denotes mounting
T15543 27756-27757 , denotes ,
T15542 27748-27756 NN denotes response
T15541 27743-27747 NNP denotes PAMP
T15540 27736-27742 JJ denotes benign
T15476 27360-27369 JJ denotes bacterial
T15475 27358-27359 DT denotes A
T15474 27356-27357 . denotes .
T15473 27355-27356 NNP denotes ]
T15472 27353-27355 CD denotes 43
T15471 27352-27353 NNP denotes [
T15470 27347-27351 NNP denotes TNFα
T15469 27342-27346 IN denotes like
T15468 27332-27341 NNS denotes mediators
T15467 27315-27331 JJ denotes pro-inflammatory
T15466 27312-27314 IN denotes of
T15465 27301-27311 NN denotes expression
T15464 27298-27300 TO denotes to
T15463 27290-27297 VBG denotes leading
T15462 27288-27289 , denotes ,
T15461 27281-27288 NN denotes pathway
T15460 27276-27280 NNP denotes NFκB
T15459 27272-27275 DT denotes the
T15458 27268-27271 IN denotes via
T15457 27258-27267 VBG denotes signaling
T15456 27247-27257 JJ denotes subsequent
T15455 27243-27246 CC denotes and
T15454 27241-27242 CD denotes 4
T15453 27232-27240 NN denotes receptor
T15452 27222-27231 JJ denotes Toll-like
T15451 27214-27221 IN denotes through
T15450 27205-27213 VBN denotes mediated
T15449 27198-27204 RB denotes mainly
T15389 26870-26872 TO denotes to
T15388 26863-26869 VBD denotes seemed
T15387 26851-26862 NNS denotes experiments
T15448 27195-27197 VBZ denotes is
T15447 27191-27194 NNP denotes LPS
T15446 27188-27190 IN denotes of
T15445 27176-27187 NN denotes Recognition
T15444 27174-27175 . denotes .
T15443 27172-27174 NNP denotes GP
T15442 27168-27171 CC denotes and
T15441 27161-27167 NNP denotes TSST-1
T15440 27159-27160 , denotes ,
T15439 27156-27159 NNP denotes LPS
T15438 27148-27155 IN denotes between
T15437 27138-27147 VBG denotes signaling
T15436 27134-27137 CC denotes and
T15435 27122-27133 NN denotes recognition
T15434 27119-27121 IN denotes in
T15433 27107-27118 NNS denotes differences
T15432 27104-27106 TO denotes to
T15431 27100-27103 JJ denotes due
T15430 27093-27099 JJ denotes likely
T15429 27090-27092 VBZ denotes is
T15428 27084-27089 WDT denotes which
T15427 27082-27083 , denotes ,
T15426 27076-27082 NNP denotes TSST-1
T15425 27073-27075 CC denotes or
T15424 27069-27072 NNP denotes LPS
T15423 27066-27068 IN denotes of
T15422 27061-27065 DT denotes that
T15421 27056-27060 IN denotes than
T15420 27045-27055 JJ denotes restricted
T15419 27040-27044 JJR denotes more
T15418 27026-27039 RB denotes substantially
T15417 27022-27025 VBD denotes was
T15416 27014-27021 NN denotes profile
T15415 27005-27013 NN denotes cytokine
T15414 26994-27004 JJ denotes GP-induced
T15413 26989-26993 DT denotes This
T15412 26987-26988 . denotes .
T15411 26986-26987 -RRB- denotes )
T15410 26981-26986 VBN denotes shown
T15409 26977-26980 RB denotes not
T15408 26972-26976 NNS denotes data
T15407 26971-26972 -LRB- denotes (
T15406 26968-26970 NNP denotes GP
T15405 26965-26967 TO denotes to
T15404 26956-26964 NN denotes response
T15403 26953-26955 IN denotes in
T15402 26946-26952 NN denotes IL-1RA
T15401 26943-26945 IN denotes as
T15400 26938-26942 RB denotes just
T15399 26933-26937 JJ denotes IL-8
T15398 26925-26932 VB denotes produce
T15397 26922-26924 TO denotes to
T15396 26917-26921 JJ denotes able
T15395 26912-26916 VBD denotes were
T15394 26900-26911 NNS denotes neutrophils
T15393 26896-26899 CC denotes and
T15392 26886-26895 NNS denotes monocytes
T15391 26881-26885 DT denotes that
T15390 26873-26880 VB denotes confirm
T15386 26840-26850 JJ denotes cytometric
T15385 26835-26839 NN denotes Flow
T15384 26833-26834 . denotes .
T15383 26832-26833 NNP denotes ]
T15382 26830-26832 CD denotes 32
T15381 26829-26830 NNP denotes [
T15380 26822-26828 NNP denotes IL-1RA
T15379 26814-26821 VB denotes produce
T15378 26811-26813 TO denotes to
T15377 26802-26810 VBN denotes reported
T15376 26797-26801 VBN denotes been
T15375 26792-26796 VBP denotes have
T15374 26780-26791 NNS denotes neutrophils
T15373 26777-26779 IN denotes as
T15372 26772-26776 RB denotes well
T15371 26769-26771 RB denotes as
T15370 26759-26768 NNS denotes monocytes
T15369 26757-26758 , denotes ,
T15368 26753-26757 DT denotes both
T15367 26751-26752 , denotes ,
T15366 26744-26751 NNS denotes sources
T15365 26735-26743 JJ denotes cellular
T15364 26725-26734 VBG denotes Regarding
T15363 26723-26724 . denotes .
T15362 26722-26723 -RRB- denotes )
T15361 26721-26722 CD denotes 7
T15360 26716-26720 NNP denotes Fig.
T15359 26715-26716 -LRB- denotes (
T15358 26708-26714 NNP denotes IL-1RA
T15357 26705-26707 IN denotes of
T15356 26695-26704 NN denotes induction
T15355 26691-26694 IN denotes for
T15354 26681-26690 JJ denotes necessary
T15353 26677-26680 CC denotes and
T15352 26671-26676 JJ denotes other
T15351 26666-26670 DT denotes each
T15350 26663-26665 TO denotes to
T15349 26656-26662 VBN denotes linked
T15348 26652-26655 VBP denotes are
T15347 26646-26651 NNS denotes steps
T15346 26640-26645 DT denotes these
T15345 26635-26639 IN denotes that
T15344 26627-26634 VB denotes suggest
T15343 26621-26626 MD denotes might
T15342 26611-26620 NN denotes treatment
T15341 26608-26610 NNP denotes GP
T15340 26605-26607 TO denotes to
T15339 26599-26604 RB denotes prior
T15338 26588-26598 NNS denotes inhibitors
T15337 26578-26587 JJ denotes selective
T15336 26575-26577 IN denotes by
T15335 26567-26574 VBN denotes induced
T15334 26559-26566 NN denotes protein
T15333 26555-26558 CC denotes and
T15332 26550-26554 NNP denotes mRNA
T15331 26543-26549 NNP denotes IL-1RA
T15330 26540-26542 IN denotes of
T15329 26537-26539 IN denotes as
T15328 26532-26536 RB denotes well
T15327 26529-26531 RB denotes as
T15326 26520-26528 NN denotes promoter
T15325 26513-26519 NN denotes IL-1RA
T15324 26509-26512 DT denotes the
T15323 26506-26508 IN denotes in
T15322 26500-26505 NNS denotes sites
T15321 26497-26499 TO denotes to
T15320 26489-26496 JJ denotes binding
T15319 26482-26488 NNP denotes NFIL-6
T15318 26478-26481 CC denotes and
T15317 26473-26477 NNP denotes NFAT
T15316 26471-26472 , denotes ,
T15315 26467-26471 NNP denotes NFκB
T15314 26464-26466 IN denotes of
T15313 26455-26463 NN denotes decrease
T15312 26442-26454 JJ denotes differential
T15311 26438-26441 DT denotes The
T15310 26436-26437 . denotes .
T15309 26428-26436 NN denotes promoter
T15308 26421-26427 NNP denotes IL-1RA
T15307 26417-26420 CC denotes and
T15306 26412-26416 NNP denotes IL-6
T15305 26410-26411 , denotes ,
T15304 26406-26410 NNP denotes IFNγ
T15303 26402-26405 DT denotes the
T15302 26394-26401 IN denotes between
T15301 26392-26393 -RRB- denotes )
T15300 26388-26392 NNP denotes NFAT
T15299 26387-26388 -LRB- denotes (
T15298 26379-26386 NNS denotes factors
T15297 26365-26378 NN denotes transcription
T15296 26355-26364 VBN denotes activated
T15295 26351-26354 DT denotes the
T15294 26348-26350 IN denotes of
T15293 26336-26347 NN denotes composition
T15292 26332-26335 DT denotes the
T15291 26329-26331 CC denotes or
T15290 26323-26328 NN denotes motif
T15289 26315-26322 JJ denotes binding
T15288 26311-26314 DT denotes the
T15287 26308-26310 IN denotes in
T15286 26296-26307 NNS denotes differences
T15285 26293-26295 TO denotes to
T15284 26289-26292 JJ denotes due
T15283 26286-26288 VB denotes be
T15282 26280-26285 MD denotes might
T15281 26274-26279 WDT denotes which
T15280 26272-26273 , denotes ,
T15279 26265-26272 JJ denotes binding
T15278 26261-26264 NNP denotes DNA
T15277 26254-26260 NNP denotes NFIL-6
T15276 26250-26253 CC denotes and
T15275 26241-26249 NNP denotes NFATP2/3
T15274 26238-26240 IN denotes of
T15273 26228-26237 NN denotes induction
T15272 26224-26227 IN denotes via
T15271 26214-26223 RB denotes primarily
T15270 26207-26213 NN denotes IL-1RA
T15269 26204-26206 IN denotes of
T15268 26193-26203 NN denotes production
T15267 26190-26192 TO denotes to
T15266 26184-26189 VBZ denotes leads
T15265 26181-26183 NNP denotes GP
T15264 26176-26180 IN denotes that
T15263 26166-26175 VBD denotes indicated
T15262 26161-26165 NNS denotes data
T15261 26157-26160 PRP$ denotes Our
T14990 24741-24751 VBG denotes describing
T14989 24733-24740 NNS denotes reports
T14988 24729-24732 JJ denotes few
T14987 24725-24728 DT denotes the
T14986 24720-24724 IN denotes with
T14985 24709-24719 NN denotes aggreement
T14984 24706-24708 IN denotes in
T14983 24702-24705 VBP denotes are
T14982 24697-24701 NNS denotes data
T14981 24693-24696 PRP$ denotes our
T14980 24691-24692 , denotes ,
T14979 24686-24691 RB denotes Hence
T14978 24684-24685 . denotes .
T14977 24683-24684 -RRB- denotes )
T14976 24681-24683 NNP denotes 3B
T14975 24676-24680 NNP denotes Fig.
T14974 24675-24676 -LRB- denotes (
T14973 24668-24674 NNP denotes IL-1RA
T14972 24664-24667 CC denotes and
T14971 24659-24663 CD denotes IL-8
T14970 24652-24658 RB denotes namely
T14969 24650-24651 , denotes ,
T14968 24642-24650 NN denotes response
T14967 24633-24641 NN denotes cytokine
T14966 24625-24632 JJ denotes limited
T14931 24405-24406 , denotes ,
T14965 24620-24624 RB denotes very
T14964 24618-24619 DT denotes a
T14963 24613-24617 IN denotes into
T14962 24608-24612 RB denotes only
T14961 24596-24607 VBN denotes transformed
T14960 24588-24595 JJ denotes binding
T14959 24581-24587 NN denotes factor
T14958 24567-24580 NN denotes transcription
T14957 24556-24566 JJ denotes GP-induced
T14956 24552-24555 DT denotes the
T14955 24550-24551 , denotes ,
T14954 24537-24550 RB denotes Interestingly
T14953 24535-24536 . denotes .
T14952 24534-24535 NNP denotes ]
T14951 24532-24534 CD denotes 38
T14950 24531-24532 NNP denotes [
T14949 24522-24530 NN denotes splicing
T14948 24510-24521 JJ denotes alternative
T14947 24505-24509 IN denotes from
T14946 24497-24504 VBN denotes derived
T14945 24488-24496 RB denotes probably
T14944 24486-24487 , denotes ,
T14943 24478-24486 NNS denotes isoforms
T14942 24473-24477 NNP denotes NFAT
T14941 24463-24472 JJ denotes different
T14940 24455-24462 JJ denotes several
T14939 24452-24454 IN denotes of
T14938 24441-24451 NN denotes activation
T14937 24438-24440 VBZ denotes is
T14936 24432-24437 EX denotes there
T14935 24427-24431 IN denotes that
T14934 24417-24426 VB denotes speculate
T14933 24411-24416 MD denotes could
T14932 24407-24410 CD denotes one
T14930 24404-24405 -RRB- denotes )
T14929 24402-24404 NNP denotes 1A
T14928 24397-24401 NNP denotes Fig.
T14927 24396-24397 -LRB- denotes (
T14926 24388-24395 JJ denotes binding
T14925 24383-24387 NNP denotes NFAT
T14924 24379-24382 IN denotes for
T14923 24370-24378 VBD denotes observed
T14922 24363-24369 NNS denotes shifts
T14921 24358-24362 NN denotes band
T14920 24349-24357 JJ denotes multiple
T14919 24345-24348 DT denotes the
T14918 24342-24344 IN denotes of
T14917 24334-24341 IN denotes Because
T14916 24332-24333 . denotes .
T14915 24323-24332 NNS denotes promoters
T14914 24314-24322 VB denotes cytokine
T14913 24311-24313 TO denotes to
T14912 24301-24310 NNS denotes NFAT-mers
T14911 24297-24300 CC denotes and
T14910 24295-24296 : denotes -
T14909 24289-24295 NNP denotes NFIL-6
T14908 24287-24288 , denotes ,
T14907 24286-24287 : denotes -
T14906 24282-24286 NNP denotes NFκB
T14905 24279-24281 IN denotes of
T14904 24271-24278 JJ denotes binding
T14903 24263-24270 VBD denotes induced
T14902 24251-24262 NNS denotes 3-D-glucans
T14901 24250-24251 NN denotes →
T14900 24247-24250 JJ denotes β-1
T14899 24245-24246 , denotes ,
T14898 24238-24245 NNS denotes stimuli
T14897 24232-24237 JJ denotes other
T14896 24229-24231 IN denotes of
T14895 24221-24228 NN denotes absence
T14894 24217-24220 DT denotes the
T14893 24214-24216 IN denotes in
T14892 24212-24213 , denotes ,
T14891 24208-24212 IN denotes that
T14890 24197-24207 VBG denotes indicating
T14889 24195-24196 NNP denotes ]
T14888 24190-24195 CD denotes 13-16
T14887 24189-24190 NNP denotes [
T14886 24181-24188 NNS denotes results
T14885 24172-24180 JJ denotes previous
T14884 24163-24171 VBD denotes extended
T14883 24159-24162 CC denotes and
T14882 24149-24158 VBD denotes confirmed
T14881 24146-24148 PRP denotes We
T14880 24144-24145 . denotes .
T14879 24142-24144 NNP denotes GP
T14878 24139-24141 IN denotes by
T14877 24129-24138 NN denotes phenotype
T14876 24111-24128 JJ denotes anti-inflammatory
T14875 24108-24110 DT denotes an
T14874 24105-24107 TO denotes to
T14873 24096-24104 VBN denotes switched
T14872 24093-24095 VBZ denotes is
T14871 24082-24092 NNS denotes leukocytes
T14870 24076-24081 JJ denotes human
T14869 24073-24075 IN denotes of
T14868 24062-24072 NN denotes expression
T14867 24053-24061 JJ denotes cytokine
T14866 24049-24052 CC denotes and
T14865 24041-24048 JJ denotes binding
T14864 24034-24040 NN denotes factor
T14863 24020-24033 NN denotes transcription
T14862 24003-24019 JJ denotes pro-inflammatory
T14861 23993-24002 VBG denotes signaling
T14860 23989-23992 CC denotes and
T14859 23977-23988 NN denotes recognition
T14858 23974-23976 IN denotes of
T14857 23963-23973 JJ denotes downstream
T14856 23958-23962 IN denotes that
T14855 23949-23957 NN denotes evidence
T14854 23943-23948 JJ denotes novel
T14853 23934-23942 VBZ denotes provides
T14852 23928-23933 NN denotes study
T14851 23924-23927 PRP$ denotes Our
T14850 23922-23923 . denotes .
T14849 23921-23922 NNP denotes ]
T14848 23916-23921 CD denotes 22,37
T14847 23915-23916 NNP denotes [
T14846 23900-23914 JJ denotes PI3K-signaling
T14845 23897-23899 TO denotes to
T14844 23895-23896 : denotes -
T14843 23891-23895 NNP denotes NFκB
T14842 23886-23890 IN denotes from
T14841 23880-23885 NN denotes shift
T14840 23874-23879 JJ denotes rapid
T14839 23872-23873 DT denotes a
T14838 23868-23871 IN denotes via
T14837 23866-23867 , denotes ,
T14836 23862-23866 NN denotes part
T14835 23859-23861 IN denotes in
T14834 23857-23858 , denotes ,
T14833 23847-23857 NNS denotes mechanisms
T14832 23836-23846 JJ denotes protective
T14831 23832-23835 PRP$ denotes its
T14830 23823-23831 VBZ denotes mediates
T14829 23820-23822 NNP denotes GP
T14828 23815-23819 IN denotes like
T14827 23804-23814 NN denotes 3-D-glucan
T14826 23803-23804 NN denotes →
T14825 23800-23803 JJ denotes β-1
T14824 23798-23799 DT denotes a
T14823 23793-23797 IN denotes that
T14822 23785-23792 VBP denotes suggest
T14821 23778-23784 NN denotes injury
T14820 23767-23777 JJ denotes myocardial
T14819 23763-23766 CC denotes and
T14818 23756-23762 NN denotes sepsis
T14817 23753-23755 IN denotes of
T14816 23746-23752 NNS denotes models
T14815 23739-23745 NNP denotes Animal
T15539 27734-27735 DT denotes a
T15538 27731-27733 TO denotes to
T15537 27727-27730 VB denotes fit
T15536 27722-27726 RB denotes well
T15535 27718-27721 MD denotes may
T15534 27716-27717 -RRB- denotes )
T15533 27714-27716 NNP denotes GP
T15532 27713-27714 -LRB- denotes (
T15531 27699-27712 NNS denotes carbohydrates
T15530 27692-27698 JJ denotes fungal
T15529 27689-27691 IN denotes by
T15528 27682-27688 NN denotes IL-1RA
T15527 27664-27681 JJ denotes anti-inflammatory
T15526 27660-27663 DT denotes the
T15525 27656-27659 CC denotes and
T15524 27651-27655 NN denotes IL-8
T15523 27629-27650 JJ denotes neutrophil-attracting
T15522 27625-27628 DT denotes the
T15521 27622-27624 IN denotes of
T15520 27612-27621 NN denotes induction
T15519 27608-27611 DT denotes the
T15518 27606-27607 , denotes ,
T15517 27596-27606 RB denotes Altogether
T15516 27594-27595 . denotes .
T15515 27593-27594 NNP denotes ]
T15514 27588-27593 CD denotes 44,45
T15513 27587-27588 NNP denotes [
T15512 27577-27586 VBG denotes signaling
T15511 27570-27576 NN denotes kinase
T15510 27552-27569 JJ denotes mitogen-activated
T15509 27548-27551 CD denotes p38
T15508 27544-27547 CC denotes and
T15507 27539-27543 NNP denotes PI3K
T15506 27537-27538 , denotes ,
T15505 27533-27537 DT denotes both
T15504 27529-27532 IN denotes via
T15503 27522-27528 JJ denotes latter
T15502 27518-27521 DT denotes the
T15501 27516-27517 , denotes ,
T15500 27512-27516 NNP denotes TNFα
T15499 27508-27511 CC denotes and
T15498 27503-27507 NNP denotes IFNγ
T15497 27496-27502 RB denotes mainly
T15496 27493-27495 IN denotes of
T15495 27485-27492 NN denotes release
T15494 27482-27484 TO denotes to
T15493 27474-27481 VBG denotes leading
T15492 27472-27473 , denotes ,
T15491 27464-27472 NN denotes receptor
T15490 27459-27463 NN denotes cell
T15489 27457-27458 NNP denotes T
T15488 27453-27456 DT denotes the
T15487 27440-27452 RB denotes subsequently
T15486 27436-27439 CC denotes and
T15485 27426-27435 NNS denotes molecules
T15484 27419-27425 NNP denotes MHC-II
T15483 27416-27418 TO denotes to
T15482 27408-27415 JJ denotes binding
T15481 27400-27407 IN denotes through
T15480 27395-27399 NNS denotes acts
T15479 27388-27394 CD denotes TSST-1
T15478 27383-27387 IN denotes like
T15477 27370-27382 NN denotes superantigen
T15260 26155-26156 . denotes .
T15259 26154-26155 -RRB- denotes )
T15258 26150-26154 CD denotes -490
T15257 26146-26149 CC denotes and
T15256 26141-26145 CD denotes -471
T15255 26140-26141 -LRB- denotes (
T15254 26135-26139 NN denotes site
T15253 26126-26134 CD denotes NFATP2/3
T15252 26119-26125 JJ denotes distal
T15251 26114-26118 RBR denotes more
T15250 26112-26113 DT denotes a
T15249 26108-26111 CC denotes and
T15248 26106-26107 -RRB- denotes )
T15247 26102-26106 CD denotes -302
T15246 26098-26101 CC denotes and
T15245 26093-26097 CD denotes -288
T15244 26092-26093 -LRB- denotes (
T15243 26087-26091 NN denotes site
T15242 26085-26086 CD denotes 3
T15241 26084-26085 NN denotes /
T15240 26079-26084 NNP denotes NFκB2
T15239 26071-26078 DT denotes another
T15238 26069-26070 , denotes ,
T15237 26068-26069 -RRB- denotes )
T15236 26064-26068 CD denotes -280
T15235 26060-26063 CC denotes and
T15234 26055-26059 CD denotes -266
T15233 26054-26055 -LRB- denotes (
T15232 26049-26053 NN denotes site
T15231 26039-26048 NN denotes consensus
T15230 26034-26038 NNP denotes NFκB
T15229 26031-26033 DT denotes an
T15228 26029-26030 , denotes ,
T15227 26028-26029 -RRB- denotes )
T15226 26024-26028 CD denotes -130
T15225 26020-26023 CC denotes and
T15224 26015-26019 CD denotes -100
T15223 26007-26014 IN denotes between
T15222 26006-26007 -LRB- denotes (
T15221 26001-26005 NN denotes site
T15220 25995-26000 JJ denotes NFκB3
T15219 25992-25994 DT denotes an
T15218 25990-25991 : denotes :
T15217 25989-25990 -RRB- denotes )
T15216 25988-25989 CD denotes 8
T15215 25983-25987 NN denotes Fig.
T15214 25982-25983 -LRB- denotes (
T15213 25976-25981 NNS denotes sites
T15212 25968-25975 JJ denotes binding
T15211 25964-25967 JJ denotes new
T15210 25959-25963 CD denotes four
T15209 25948-25958 VBD denotes discovered
T15208 25945-25947 PRP denotes we
T15207 25943-25944 , denotes ,
T15206 25942-25943 NNP denotes ]
T15205 25940-25942 CD denotes 34
T15204 25939-25940 NNP denotes [
T15203 25930-25938 NN denotes promoter
T15202 25923-25929 NN denotes IL-1RA
T15201 25919-25922 DT denotes the
T15200 25909-25918 VBG denotes Analysing
T15199 25907-25908 . denotes .
T15198 25905-25907 NNP denotes GP
T15197 25902-25904 IN denotes of
T15196 25892-25901 NN denotes potential
T15195 25874-25891 JJ denotes anti-inflammatory
T15194 25864-25873 JJ denotes immediate
T15193 25861-25863 DT denotes an
T15192 25850-25860 VBG denotes suggesting
T15191 25848-25849 , denotes ,
T15190 25842-25848 NNP denotes IL-1RA
T15189 25834-25841 VBD denotes induced
T15188 25825-25833 RB denotes strongly
T15187 25822-25824 PRP denotes it
T15186 25818-25821 CC denotes but
T15185 25816-25817 , denotes ,
T15184 25811-25816 NN denotes IL-1β
T15180 25793-25795 NNP denotes GP
T15179 25788-25792 IN denotes that
T15178 25782-25787 VBD denotes found
T15177 25779-25781 PRP denotes we
T15176 25777-25778 , denotes ,
T15175 25771-25777 NNP denotes TSST-1
T15174 25768-25770 CC denotes or
T15173 25764-25767 NNP denotes LPS
T15172 25757-25763 IN denotes Unlike
T15171 25755-25756 . denotes .
T15170 25754-25755 NNP denotes ]
T15169 25749-25754 CD denotes 41,42
T15168 25748-25749 NNP denotes [
T15167 25742-25747 NN denotes motif
T15166 25739-25741 NN denotes κB
T15165 25729-25738 JJ denotes decameric
T15164 25725-25728 DT denotes the
T15163 25722-25724 IN denotes of
T15162 25713-25721 NN denotes sequence
T15161 25704-25712 JJ denotes specific
T15160 25700-25703 DT denotes the
T15159 25696-25699 CC denotes and
T15158 25687-25695 NNS denotes subunits
T15157 25683-25686 DT denotes the
T15156 25680-25682 IN denotes of
T15155 25667-25679 NNS denotes associations
T15154 25653-25666 JJ denotes combinatorial
T15153 25645-25652 IN denotes through
T15152 25637-25644 JJ denotes binding
T15151 25632-25636 NNP denotes NFκB
T15150 25621-25631 VBG denotes regulating
T15149 25618-25620 IN denotes of
T15148 25613-25617 NN denotes idea
T15147 25609-25612 DT denotes the
T15146 25598-25608 VBG denotes supporting
T15145 25596-25597 , denotes ,
T15144 25595-25596 NNP denotes ]
T15143 25590-25595 CD denotes 27,40
T15142 25589-25590 NNP denotes [
T15141 25583-25588 NNP denotes IL-1β
T15140 25579-25582 CC denotes and
T15139 25574-25578 NNP denotes TNFα
T15138 25570-25573 IN denotes for
T15137 25560-25569 VBN denotes described
T15136 25555-25559 NN denotes site
T15135 25550-25554 NN denotes half
T15134 25547-25549 NNP denotes κB
T15133 25543-25546 DT denotes the
T15132 25538-25542 IN denotes from
T15131 25530-25537 VBZ denotes differs
T15130 25525-25529 RB denotes thus
T15129 25521-25524 CC denotes and
T15128 25516-25520 NN denotes site
T15127 25511-25515 NN denotes half
T15126 25503-25510 JJ denotes binding
T15125 25499-25502 JJ denotes p65
T15124 25484-25498 RB denotes preferentially
T15123 25482-25483 DT denotes a
T15122 25473-25481 VBZ denotes exhibits
T15121 25468-25472 NN denotes site
T15120 25458-25467 NN denotes consensus
T15119 25451-25457 NN denotes IL-8κB
T15118 25447-25450 DT denotes The
T15117 25445-25446 . denotes .
T15116 25437-25445 JJ denotes possible
T15115 25432-25436 RB denotes also
T15114 25426-25431 VBZ denotes seems
T15113 25424-25425 NNP denotes ]
T15112 25422-25424 CD denotes 38
T15111 25421-25422 NNP denotes [
T15110 25416-25420 NN denotes site
T15109 25409-25415 NN denotes IL-8κB
T15108 25405-25408 DT denotes the
T15107 25402-25404 TO denotes to
T15106 25394-25401 JJ denotes binding
T15105 25388-25393 NN denotes dimer
T15104 25381-25387 NNP denotes NFATc2
T15103 25378-25380 CC denotes or
T15102 25376-25377 NNP denotes ]
T15101 25371-25376 CD denotes 13,39
T15100 25370-25371 NNP denotes [
T15099 25363-25369 NNP denotes NFIL-6
T15098 25359-25362 CC denotes and
T15097 25355-25358 CD denotes p65
T15096 25350-25354 NNP denotes NFκB
T15095 25335-25349 VBN denotes transactivated
T15094 25327-25334 IN denotes between
T15093 25315-25326 NN denotes cooperation
T15092 25313-25314 DT denotes a
T15091 25308-25312 IN denotes upon
T15090 25302-25307 VBN denotes based
T15089 25288-25301 NN denotes transcription
T15088 25283-25287 NN denotes IL-8
T15087 25271-25282 JJ denotes GP-mediated
T15086 25269-25270 DT denotes A
T15085 25267-25268 . denotes .
T15084 25254-25267 NN denotes transcription
T15083 25249-25253 NN denotes IL-8
T15082 25237-25248 JJ denotes GP-mediated
T15081 25233-25236 DT denotes the
T15080 25229-25232 IN denotes for
T15079 25224-25228 NN denotes case
T15078 25220-25223 DT denotes the
T15077 25217-25219 VB denotes be
T15076 25211-25216 MD denotes might
T15075 25205-25210 WDT denotes which
T15074 25203-25204 , denotes ,
T15073 25191-25203 NNS denotes heterodimers
T15072 25184-25190 CD denotes p65/50
T15071 25180-25183 IN denotes via
T15070 25175-25179 IN denotes than
T15069 25168-25174 RB denotes rather
T15068 25166-25167 , denotes ,
T15067 25157-25166 NN denotes homodimer
T15066 25150-25156 CD denotes p65/65
T15065 25145-25149 NNP denotes NFκB
T15064 25142-25144 DT denotes an
T15063 25138-25141 IN denotes via
T15062 25127-25137 NN denotes activation
T15061 25124-25126 IN denotes on
T15060 25114-25123 VBG denotes depending
T15059 25100-25113 NN denotes transcription
T15058 25095-25099 NN denotes IL-8
T15057 25092-25094 IN denotes of
T15056 25082-25091 NN denotes induction
T15055 25079-25081 DT denotes an
T15054 25076-25078 TO denotes to
T15053 25068-25075 VBD denotes pointed
T15052 25066-25067 NNP denotes ]
T15051 25064-25066 CD denotes 28
T15050 25063-25064 NNP denotes [
T15049 25052-25062 NNS denotes colleagues
T15048 25048-25051 CC denotes and
T15047 25040-25047 NNP denotes Schulte
T15046 25037-25039 IN denotes by
T15045 25029-25036 NNS denotes Results
T15044 25027-25028 . denotes .
T15043 25026-25027 -RRB- denotes )
T15042 25025-25026 CD denotes 2
T15041 25023-25024 , denotes ,
T15040 25021-25023 NNP denotes 1A
T15039 25015-25020 NNP denotes Figs.
T15038 25014-25015 -LRB- denotes (
T15037 25005-25013 NN denotes promoter
T15036 25000-25004 NN denotes IL-8
T15035 24996-24999 DT denotes the
T15034 24993-24995 IN denotes of
T15033 24988-24992 NN denotes site
T15032 24978-24987 NN denotes consensus
T15031 24975-24977 NN denotes κB
T15030 24973-24974 DT denotes a
T15029 24970-24972 TO denotes to
T15028 24966-24969 CD denotes p50
T15027 24963-24965 IN denotes of
T15026 24956-24962 NN denotes extent
T15025 24949-24955 JJR denotes lesser
T15024 24947-24948 DT denotes a
T15023 24944-24946 TO denotes to
T15022 24940-24943 CC denotes and
T15021 24936-24939 CD denotes p65
T15020 24931-24935 NNP denotes NFκB
T15019 24928-24930 IN denotes of
T15018 24920-24927 JJ denotes binding
T15017 24908-24919 NN denotes predominant
T15016 24896-24907 JJ denotes GP-mediated
T15015 24894-24895 DT denotes a
T15014 24881-24893 VBD denotes demonstrated
T15013 24873-24880 NNS denotes results
T15012 24858-24872 VBG denotes immunoblotting
T15011 24854-24857 CC denotes and
T15010 24838-24853 NNP denotes EMSA/supershift
T15009 24834-24837 PRP$ denotes our
T15008 24832-24833 , denotes ,
T15007 24824-24832 NN denotes addition
T15006 24821-24823 IN denotes In
T15005 24819-24820 . denotes .
T15002 24815-24816 NNP denotes [
T15001 24804-24814 NN denotes production
T15000 24797-24803 NNP denotes IL-1RA
T14999 24793-24796 CC denotes and
T14998 24791-24792 NNP denotes ]
T14997 24784-24791 CD denotes 6,16,19
T14996 24783-24784 NNP denotes [
T14995 24778-24782 NN denotes IL-8
T14994 24758-24777 JJ denotes 3-D-glucan-mediated
T14993 24757-24758 NN denotes →
T14992 24754-24757 JJ denotes β-1
T14991 24752-24753 DT denotes a
T15183 25804-25810 VB denotes induce
T15182 25800-25803 RB denotes not
T15181 25796-25799 VBD denotes did
T11121 22681-22685 RBR denotes more
T11120 22677-22680 VBD denotes was
T11119 22672-22676 NNP denotes CAPE
T11118 22669-22671 IN denotes by
T11117 22658-22668 NN denotes inhibition
T11116 22653-22657 NNP denotes NFκB
T11115 22651-22652 , denotes ,
T11114 22641-22651 RB denotes Altogether
T11113 22639-22640 . denotes .
T11112 22638-22639 -RRB- denotes )
T11111 22637-22638 LS denotes 3
T11110 22635-22636 SYM denotes =
T11109 22633-22634 FW denotes n
T11108 22632-22633 -LRB- denotes (
T11107 22629-22631 NNP denotes 7C
T11106 22624-22628 NNP denotes Fig.
T11105 22621-22623 IN denotes in
T11104 22615-22620 VBN denotes shown
T11103 22611-22614 VBP denotes are
T11102 22608-22610 NNP denotes GP
T11101 22605-22607 IN denotes of
T11100 22603-22604 NN denotes h
T11099 22600-22602 CD denotes 24
T11098 22594-22599 IN denotes after
T11097 22587-22593 NNS denotes levels
T11096 22579-22586 NN denotes protein
T11095 22572-22578 NN denotes IL-1RA
T11094 22558-22571 JJ denotes corresponding
T11093 22556-22557 , denotes ,
T11092 22548-22556 NN denotes addition
T11091 22545-22547 IN denotes In
T11037 22296-22297 -RRB- denotes )
T11036 22291-22296 VBN denotes shown
T11035 22287-22290 RB denotes not
T11034 22282-22286 NNS denotes data
T11033 22281-22282 -LRB- denotes (
T11032 22273-22280 JJ denotes similar
T11031 22268-22272 VBD denotes were
T11030 22262-22267 NNS denotes sites
T11029 22254-22261 JJ denotes binding
T11028 22247-22253 NNP denotes NFIL-6
T11027 22243-22246 CC denotes and
T11026 22238-22242 NNP denotes NFκB
T11025 22234-22237 DT denotes the
T11024 22230-22233 IN denotes for
T11023 22222-22229 NNS denotes results
T11022 22218-22221 DT denotes The
T11021 22216-22217 . denotes .
T11020 22215-22216 -RRB- denotes )
T11019 22211-22215 NN denotes side
T11018 22205-22210 JJ denotes right
T11017 22203-22204 , denotes ,
T11016 22201-22203 NN denotes 7A
T11015 22196-22200 NNP denotes Fig.
T11014 22194-22195 , denotes ,
T11013 22193-22194 CD denotes 4
T11012 22191-22192 SYM denotes =
T11011 22189-22190 FW denotes n
T11010 22188-22189 -LRB- denotes (
T11009 22177-22187 VBN denotes summarized
T11008 22165-22176 RB denotes graphically
T11007 22161-22164 CC denotes and
T11006 22159-22160 -RRB- denotes )
T11005 22155-22159 NN denotes side
T11004 22150-22154 VBD denotes left
T11003 22148-22149 , denotes ,
T11002 22146-22148 NN denotes 7A
T11001 22141-22145 NNP denotes Fig.
T11000 22140-22141 -LRB- denotes (
T10999 22126-22139 NN denotes autoradiogram
T10998 22123-22125 DT denotes an
T10997 22120-22122 IN denotes in
T10939 21824-21825 , denotes ,
T10938 21821-21824 NNP denotes CyA
T10937 21817-21820 CC denotes and
T10936 21815-21816 NNP denotes ]
T10935 21813-21815 CD denotes 35
T10934 21812-21813 NNP denotes [
T10933 21807-21811 NNP denotes CAPE
T10932 21803-21806 IN denotes via
T10931 21798-21802 NNP denotes NFκB
T10930 21795-21797 IN denotes of
T10929 21784-21794 NN denotes inhibition
T10928 21781-21783 DT denotes an
T10927 21779-21780 , denotes ,
T10926 21771-21779 VBN denotes expected
T10925 21768-21770 IN denotes As
T10924 21766-21767 . denotes .
T10923 21764-21766 NNP denotes GP
T10922 21761-21763 IN denotes by
T10921 21754-21760 NN denotes IL-1RA
T10920 21751-21753 IN denotes of
T10919 21741-21750 NN denotes induction
T10918 21737-21740 DT denotes the
T10917 21733-21736 IN denotes for
T10916 21724-21732 JJ denotes relevant
T10915 21720-21723 VBP denotes are
T10914 21711-21719 NN denotes promoter
T10913 21704-21710 NN denotes IL-1RA
T10912 21700-21703 DT denotes the
T10911 21693-21699 IN denotes within
T10910 21687-21692 NNS denotes sites
T10909 21680-21686 NN denotes factor
T10908 21666-21679 NN denotes transcription
T10907 21662-21665 DT denotes the
T10906 21657-21661 IN denotes that
T11142 22804-22805 . denotes .
T11141 22797-22804 NN denotes release
T11140 22790-22796 NN denotes IL-1RA
T11139 22780-22789 VBN denotes decreased
T11138 22778-22779 DT denotes a
T11137 22775-22777 TO denotes to
T11136 22771-22774 VBD denotes led
T11135 22764-22770 RB denotes mainly
T11134 22760-22763 NNP denotes CHX
T11133 22756-22759 CC denotes and
T11132 22752-22755 NNP denotes CyA
T11131 22744-22751 IN denotes whereas
T11130 22742-22743 , denotes ,
T11129 22729-22742 NN denotes transcription
T11128 22725-22728 DT denotes the
T11127 22721-22724 CC denotes and
T11126 22712-22720 NN denotes activity
T11125 22704-22711 JJ denotes binding
T11124 22700-22703 DT denotes the
T11123 22697-22699 IN denotes at
T11122 22686-22696 JJ denotes pronounced
T10905 21645-21656 VB denotes demonstrate
T10904 21642-21644 TO denotes to
T10903 21637-21641 VBN denotes used
T10902 21632-21636 VBD denotes were
T10901 21621-21631 NNS denotes inhibitors
T10900 21605-21620 JJ denotes Pharmacological
T10899 21598-21604 NNS denotes levels
T10898 21591-21597 NN denotes IL-1RA
T10897 21583-21590 VBN denotes reduced
T10896 21580-21582 TO denotes to
T10895 21576-21579 VBD denotes led
T10894 21568-21575 NNS denotes factors
T10893 21554-21567 NN denotes transcription
T10892 21551-21553 IN denotes of
T10891 21540-21550 NNP denotes Inhibition
T10107 20176-20179 DT denotes the
T10106 20173-20175 IN denotes in
T10105 20171-20172 NN denotes h
T10104 20168-20170 CD denotes 48
T10103 20165-20167 IN denotes of
T10102 20158-20164 NN denotes course
T10101 20153-20157 NN denotes time
T10100 20151-20152 DT denotes a
T10099 20146-20150 IN denotes over
T10098 20134-20145 NNS denotes alterations
T10097 20122-20133 JJ denotes substantial
T10096 20117-20121 VB denotes find
T10095 20113-20116 RB denotes not
T10094 20109-20112 VBD denotes did
T10093 20106-20108 PRP denotes we
T10092 20104-20105 , denotes ,
T10091 20101-20104 NNP denotes LPS
T10090 20099-20100 FW denotes +
T10089 20096-20098 NNP denotes GP
T10088 20092-20095 FW denotes vs.
T10087 20088-20091 NNP denotes LPS
T10086 20078-20087 VBG denotes Comparing
T10085 20075-20077 NN denotes h.
T10084 20072-20074 CD denotes 24
T10083 20069-20071 TO denotes to
T10082 20066-20068 RP denotes up
T10081 20061-20065 FW denotes i.e.
T10080 20059-20060 , denotes ,
T10079 20053-20059 NNS denotes points
T10078 20048-20052 NN denotes time
T10077 20042-20047 JJ denotes early
T10076 20039-20041 IN denotes at
T10075 20032-20038 NN denotes IL-1RA
T10074 20027-20031 IN denotes than
T10073 20021-20026 JJ denotes IL-1β
T10072 20016-20020 RBR denotes more
T10071 20005-20015 VBG denotes generating
T10070 20002-20004 IN denotes in
T10069 19993-20001 VBD denotes resulted
T10068 19982-19992 NNS denotes treatments
T10067 19978-19981 NNP denotes LPS
T10066 19976-19977 NNP denotes +
T10065 19973-19975 NNP denotes GP
T10064 19969-19972 CC denotes and
T10063 19965-19968 NNP denotes LPS
T10062 19963-19964 , denotes ,
T10061 19959-19963 DT denotes Both
T10060 19957-19958 . denotes .
T10059 19945-19957 NN denotes inflammation
T10058 19942-19944 IN denotes of
T10057 19935-19941 NN denotes degree
T10056 19931-19934 DT denotes the
T10055 19928-19930 IN denotes of
T10054 19918-19927 NN denotes indicator
T10053 19915-19917 DT denotes an
T10052 19912-19914 IN denotes as
T10051 19906-19911 NN denotes ratio
T10050 19899-19905 NN denotes IL-1RA
T10049 19898-19899 NN denotes /
T10048 19893-19898 JJ denotes IL-1β
T10047 19889-19892 DT denotes the
T10046 19881-19888 VBD denotes applied
T10045 19878-19880 PRP denotes we
T10044 19876-19877 , denotes ,
T10043 19867-19876 RB denotes Therefore
T10042 19865-19866 . denotes .
T10041 19859-19865 NN denotes action
T10040 19841-19858 JJ denotes anti-inflammatory
T10039 19838-19840 CC denotes or
T10038 19833-19837 JJ denotes pro-
T10037 19828-19832 FW denotes i.e.
T10036 19826-19827 , denotes ,
T10035 19822-19826 NN denotes coin
T10034 19820-19821 DT denotes a
T10033 19817-19819 IN denotes of
T10032 19811-19816 NNS denotes sides
T10031 19807-19810 CD denotes two
T10030 19797-19806 VB denotes represent
T10029 19791-19796 MD denotes might
T10028 19784-19790 NN denotes IL-1RA
T10027 19780-19783 CC denotes and
T10026 19774-19779 NN denotes IL-1β
T10025 19772-19773 , denotes ,
T10024 19764-19772 NN denotes approach
T10023 19753-19763 VBN denotes simplified
T10022 19751-19752 DT denotes a
T10021 19748-19750 IN denotes In
T10242 20799-20800 . denotes .
T10241 20798-20799 -RRB- denotes )
T10240 20794-20798 CD denotes 0.07
T10239 20792-20793 NN denotes <
T10238 20790-20791 VB denotes p
T10237 20788-20789 : denotes ;
T10236 20787-20788 CD denotes 4
T10235 20785-20786 SYM denotes =
T10234 20783-20784 NN denotes n
T10233 20781-20782 , denotes ,
T10232 20775-20781 NN denotes detail
T10231 20772-20774 IN denotes in
T10230 20766-20771 VBN denotes shown
T10229 20762-20765 RB denotes not
T10228 20757-20761 NNS denotes data
T10227 20756-20757 -LRB- denotes (
T10226 20754-20755 . denotes .
T10225 20750-20754 NN denotes calc
T10224 20747-20749 CD denotes -1
T10223 20740-20747 NNP denotes GP/TSST
T10222 20737-20739 CC denotes or
T10221 20730-20736 CD denotes TSST-1
T10220 20727-20729 TO denotes to
T10219 20718-20726 VBN denotes compared
T10218 20713-20717 WRB denotes when
T10217 20706-20712 NNP denotes TSST-1
T10216 20704-20705 NNP denotes +
T10215 20701-20703 NNP denotes GP
T10214 20691-20700 VBG denotes following
T10213 20685-20690 NNS denotes cells
T10212 20680-20684 NN denotes EL-4
T10211 20673-20679 JJ denotes murine
T10210 20668-20672 IN denotes from
T10209 20663-20667 NN denotes IL-2
T10208 20660-20662 IN denotes of
T10207 20652-20659 NN denotes release
T10206 20642-20651 JJ denotes dependent
T10205 20637-20641 NN denotes IL-1
T10204 20633-20636 DT denotes the
T10203 20630-20632 IN denotes of
T10202 20621-20629 NN denotes decrease
T10201 20619-20620 DT denotes a
T10200 20616-20618 IN denotes by
T10199 20606-20615 VBN denotes suggested
T10198 20602-20605 VBD denotes was
T10197 20595-20601 NN denotes result
T10196 20590-20594 DT denotes this
T10195 20587-20589 IN denotes of
T10194 20577-20586 NN denotes relevance
T10193 20566-20576 JJ denotes biological
T10192 20564-20565 DT denotes A
T10191 20562-20563 . denotes .
T10190 20561-20562 -RRB- denotes )
T10189 20560-20561 CD denotes 6
T10188 20555-20559 NNP denotes Fig.
T10187 20553-20554 : denotes ;
T10186 20549-20553 CD denotes 0.05
T10185 20547-20548 CD denotes <
T10184 20545-20546 VBP denotes p
T10183 20540-20544 DT denotes both
T10182 20538-20539 : denotes ;
T10181 20537-20538 CD denotes 3
T10180 20535-20536 SYM denotes =
T10179 20533-20534 FW denotes n
T10178 20532-20533 -LRB- denotes (
T10177 20526-20531 NN denotes IL-1β
T10176 20523-20525 IN denotes of
T10175 20518-20522 IN denotes than
T10174 20511-20517 NN denotes IL-1RA
T10173 20508-20510 IN denotes of
T10172 20497-20507 NN denotes production
T10171 20490-20496 JJR denotes higher
T10170 20488-20489 FW denotes a
T10169 20483-20487 FW denotes i.e.
T10168 20481-20482 , denotes ,
T10167 20471-20481 NN denotes incubation
T10166 20468-20470 IN denotes of
T10165 20466-20467 NN denotes h
T10164 20463-20465 CD denotes 24
T10163 20459-20462 CC denotes and
T10162 20457-20458 NN denotes h
T10161 20454-20456 CD denotes 18
T10160 20451-20453 IN denotes at
T10159 20445-20450 NN denotes ratio
T10158 20437-20444 VBN denotes reduced
T10157 20432-20436 VBP denotes fold
T10156 20428-20431 CD denotes 100
T10155 20425-20427 CD denotes 10
T10154 20419-20424 IN denotes about
T10153 20416-20418 DT denotes an
T10152 20413-20415 IN denotes by
T10151 20400-20412 VBN denotes demonstrated
T10150 20397-20399 IN denotes as
T10149 20395-20396 , denotes ,
T10148 20393-20395 NNP denotes GP
T10147 20390-20392 IN denotes of
T10146 20383-20389 NN denotes action
T10145 20365-20382 JJ denotes anti-inflammatory
T10144 20354-20364 JJ denotes pronounced
T10143 20352-20353 DT denotes a
T10142 20343-20351 VBD denotes observed
T10141 20340-20342 PRP denotes we
T10140 20338-20339 , denotes ,
T10139 20332-20338 NNP denotes TSST-1
T10138 20330-20331 NNP denotes +
T10137 20327-20329 NNP denotes GP
T10136 20323-20326 IN denotes vs.
T10135 20321-20322 . denotes .
T10134 20317-20321 NN denotes calc
T10133 20314-20316 CD denotes -1
T10132 20307-20314 NNP denotes GP/TSST
T10131 20304-20306 IN denotes of
T10130 20298-20303 NN denotes value
T10129 20286-20297 JJ denotes theoretical
T10128 20282-20285 DT denotes the
T10127 20279-20281 CC denotes or
T10126 20272-20278 CD denotes TSST-1
T10125 20269-20271 TO denotes to
T10124 20261-20268 NN denotes respect
T10123 20256-20260 IN denotes With
T10122 20253-20255 NN denotes h.
T10121 20251-20252 CD denotes 6
T10120 20248-20250 IN denotes at
T10119 20242-20247 NN denotes ratio
T10118 20235-20241 JJR denotes higher
T10117 20230-20234 VBP denotes fold
T10116 20227-20230 CD denotes 2.5
T10115 20209-20224 JJ denotes non-significant
T10114 20205-20206 DT denotes a
T10113 20200-20204 RB denotes only
T10112 20198-20199 , denotes ,
T10111 20193-20198 NN denotes ratio
T10110 20186-20192 NN denotes IL-1RA
T10109 20185-20186 NN denotes /
T10108 20180-20185 JJ denotes IL-1β
T9265 18344-18347 VBD denotes was
T9264 18342-18343 -RRB- denotes )
T9263 18336-18342 CD denotes TSST-1
T9262 18333-18335 IN denotes of
T9261 18328-18332 VBP denotes fold
T9260 18324-18328 CD denotes 1.25
T9259 18322-18323 , denotes ,
T9258 18320-18322 NNP denotes GP
T9257 18317-18319 IN denotes of
T9256 18312-18316 VBP denotes fold
T9255 18309-18312 CD denotes 1.5
T9254 18308-18309 -LRB- denotes (
T9253 18301-18307 NNP denotes TSST-1
T9252 18299-18300 NNP denotes +
T9251 18296-18298 NNP denotes GP
T9250 18292-18295 CC denotes and
T9249 18290-18291 -RRB- denotes )
T9248 18288-18290 NNP denotes GP
T9247 18285-18287 IN denotes of
T9246 18280-18284 VBP denotes fold
T9245 18277-18280 CD denotes 1.4
T9244 18276-18277 -LRB- denotes (
T9243 18272-18275 NNP denotes LPS
T9242 18270-18271 NNP denotes +
T9241 18267-18269 NNP denotes GP
T9240 18265-18266 , denotes ,
T9239 18261-18265 DT denotes both
T9238 18251-18260 VBG denotes following
T9237 18246-18250 NN denotes site
T9236 18237-18245 NNP denotes NFATP2/3
T9235 18233-18236 DT denotes the
T9234 18230-18232 TO denotes to
T9233 18222-18229 JJ denotes binding
T9232 18220-18221 , denotes ,
T9231 18212-18220 NN denotes addition
T9230 18209-18211 IN denotes In
T9229 18207-18208 . denotes .
T9228 18206-18207 -RRB- denotes )
T9227 18202-18206 CD denotes 0.05
T9226 18200-18201 FW denotes <
T9225 18198-18199 FW denotes p
T9224 18197-18198 -LRB- denotes (
T9223 18189-18196 NN denotes control
T9222 18182-18188 JJ denotes medium
T9221 18179-18181 TO denotes to
T9220 18170-18178 VBN denotes compared
T9219 18165-18169 WRB denotes when
T9218 18163-18164 , denotes ,
T9217 18151-18163 NNS denotes combinations
T9216 18147-18150 CC denotes and
T9215 18137-18146 NNS denotes compounds
T9214 18133-18136 DT denotes all
T9213 18129-18132 IN denotes for
T9212 18121-18128 JJ denotes binding
T9211 18118-18120 IN denotes of
T9210 18109-18117 NN denotes increase
T9209 18097-18108 JJ denotes substantial
T9208 18095-18096 DT denotes a
T9207 18089-18094 RB denotes again
T9206 18078-18088 VBG denotes displaying
T9205 18076-18077 , denotes ,
T9204 18072-18076 CD denotes -490
T9203 18068-18071 CC denotes and
T9202 18063-18067 CD denotes -471
T9201 18055-18062 IN denotes between
T9200 18053-18054 , denotes ,
T9199 18049-18053 NN denotes site
T9198 18043-18048 VB denotes start
T9197 18029-18042 NN denotes transcription
T9196 18025-18028 DT denotes the
T9195 18022-18024 IN denotes of
T9194 18015-18021 JJ denotes distal
T9193 18010-18014 RBR denotes more
T9192 18004-18009 VBN denotes found
T9191 18000-18003 VBD denotes was
T9190 17991-17999 NNP denotes NFATP2/3
T9189 17987-17990 IN denotes for
T9188 17982-17986 NN denotes site
T9187 17974-17981 JJ denotes binding
T9186 17970-17973 JJ denotes new
T9185 17968-17969 DT denotes A
T9184 17966-17967 . denotes .
T9183 17965-17966 -RRB- denotes )
T9182 17960-17965 VBN denotes shown
T9181 17956-17959 RB denotes not
T9180 17951-17955 NNS denotes data
T9179 17950-17951 -LRB- denotes (
T9178 17948-17949 , denotes ,
T9177 17947-17948 -RRB- denotes )
T9176 17943-17947 CD denotes 0.05
T9175 17941-17942 RB denotes <
T9174 17939-17940 VB denotes p
T9173 17937-17938 : denotes ;
T9172 17933-17937 VBP denotes fold
T9171 17930-17933 CD denotes 1.6
T9170 17929-17930 -LRB- denotes (
T9169 17926-17928 NNP denotes GP
T9168 17923-17925 CC denotes or
T9167 17921-17922 -RRB- denotes )
T9166 17917-17921 VBP denotes fold
T9165 17914-17917 CD denotes 1.3
T9164 17913-17914 -LRB- denotes (
T9163 17906-17912 CD denotes TSST-1
T9162 17901-17905 IN denotes with
T9161 17890-17900 NN denotes comparison
T9160 17887-17889 IN denotes in
T9159 17882-17886 NN denotes site
T9158 17875-17881 NNP denotes NFIL-6
T9157 17871-17874 DT denotes the
T9156 17868-17870 TO denotes to
T9155 17860-17867 JJ denotes binding
T9154 17850-17859 VBN denotes increased
T9153 17847-17849 DT denotes an
T9152 17839-17846 VBD denotes induced
T9151 17832-17838 NNP denotes TSST-1
T9150 17830-17831 NNP denotes +
T9149 17827-17829 NNP denotes GP
T9148 17825-17826 , denotes ,
T9147 17818-17825 RB denotes Further
T9146 17816-17817 . denotes .
T9145 17815-17816 -RRB- denotes )
T9144 17811-17815 CD denotes 0.05
T9143 17809-17810 FW denotes <
T9142 17807-17808 FW denotes p
T9141 17806-17807 -LRB- denotes (
T9140 17804-17805 NN denotes %
T9139 17801-17804 CD denotes 110
T9138 17798-17800 CD denotes 25
T9137 17793-17797 IN denotes from
T9136 17785-17792 VBG denotes ranging
T9135 17783-17784 , denotes ,
T9134 17776-17783 NN denotes control
T9133 17769-17775 NN denotes medium
T9132 17765-17768 IN denotes vs.
T9131 17752-17764 NNS denotes combinations
T9130 17748-17751 CC denotes and
T9129 17738-17747 NNS denotes compounds
T9128 17734-17737 DT denotes all
T9127 17730-17733 IN denotes for
T9126 17722-17729 JJ denotes binding
T9125 17719-17721 IN denotes of
T9124 17705-17718 NN denotes up-regulation
T9123 17702-17704 DT denotes an
T9122 17695-17701 VBD denotes showed
T9121 17693-17694 NNP denotes ]
T9120 17688-17693 CD denotes 31,32
T9119 17687-17688 NNP denotes [
T9118 17681-17686 NNP denotes LRE-2
T9117 17678-17680 TO denotes to
T9116 17672-17677 RB denotes close
T9115 17670-17671 -RRB- denotes )
T9114 17666-17670 CD denotes -170
T9113 17662-17665 CC denotes and
T9112 17657-17661 CD denotes -147
T9111 17656-17657 -LRB- denotes (
T9110 17651-17655 NN denotes site
T9109 17644-17650 NNP denotes NFIL-6
T9108 17640-17643 DT denotes The
T9107 17638-17639 . denotes .
T9106 17637-17638 -RRB- denotes )
T9105 17632-17637 VBN denotes shown
T9104 17628-17631 RB denotes not
T9103 17623-17627 NNS denotes data
T9102 17621-17622 : denotes ;
T9101 17617-17621 CD denotes 0.05
T9100 17615-17616 FW denotes <
T9099 17613-17614 FW denotes p
T9098 17612-17613 -LRB- denotes (
T9097 17604-17611 NN denotes control
T9096 17597-17603 JJ denotes medium
T9095 17592-17596 IN denotes with
T9094 17581-17591 NN denotes comparison
T9093 17578-17580 IN denotes in
T9092 17576-17577 NN denotes %
T9091 17574-17576 CD denotes 35
T9090 17571-17573 CD denotes 20
T9089 17565-17570 RB denotes about
T9088 17562-17564 IN denotes by
T9087 17547-17561 VBN denotes down-regulated
T9086 17543-17546 VBD denotes was
T9085 17541-17542 -RRB- denotes )
T9084 17537-17541 CD denotes -302
T9083 17533-17536 CC denotes and
T9082 17528-17532 CD denotes -288
T9081 17527-17528 -LRB- denotes (
T9080 17522-17526 NN denotes site
T9079 17520-17521 CD denotes 3
T9078 17519-17520 NN denotes /
T9077 17516-17519 NNP denotes κB2
T9076 17512-17515 JJ denotes new
T9075 17508-17511 DT denotes the
T9074 17505-17507 TO denotes to
T9073 17497-17504 JJ denotes binding
T9072 17485-17496 JJ denotes LPS-induced
T9071 17483-17484 NNP denotes +
T9070 17480-17482 NNP denotes GP
T9069 17476-17479 CC denotes and
T9068 17474-17475 : denotes -
T9067 17468-17474 NNP denotes TSST-1
T9066 17466-17467 , denotes ,
T9065 17465-17466 : denotes -
T9064 17462-17465 NNP denotes LPS
T9063 17458-17461 DT denotes The
T9062 17456-17457 . denotes .
T9061 17455-17456 -RRB- denotes )
T9060 17450-17455 VBN denotes shown
T9059 17446-17449 RB denotes not
T9058 17441-17445 NNS denotes data
T9057 17439-17440 : denotes ;
T9056 17435-17439 CD denotes 0.05
T9055 17433-17434 NN denotes <
T9054 17431-17432 JJ denotes p
T9053 17430-17431 -LRB- denotes (
T9052 17423-17429 NNP denotes TSST-1
T9051 17421-17422 NNP denotes +
T9050 17418-17420 NNP denotes GP
T8913 16782-16783 NNP denotes ]
T8912 16780-16782 CD denotes 30
T8911 16779-16780 NNP denotes [
T8910 16777-16778 -RRB- denotes )
T8909 16774-16777 CD denotes -93
T8908 16770-16773 CC denotes and
T8907 16766-16769 CD denotes -84
T8906 16758-16765 IN denotes between
T8905 16757-16758 -LRB- denotes (
T8904 16751-16756 NNP denotes LRE-1
T8903 16748-16750 IN denotes of
T8902 16743-16747 NN denotes site
T8901 16733-16742 NN denotes consensus
T8900 16730-16732 NN denotes κB
T8899 16719-16729 JJ denotes responsive
T8898 16715-16718 NNP denotes LPS
T8897 16711-16714 DT denotes The
T8896 16709-16710 . denotes .
T8895 16708-16709 -RRB- denotes )
T8894 16706-16708 NNP denotes UK
T8893 16704-16705 , denotes ,
T8892 16698-16704 NNP denotes Oxford
T8891 16696-16697 , denotes ,
T8890 16687-16696 NNP denotes Molecular
T8889 16680-16686 NNP denotes Oxford
T8888 16678-16679 , denotes ,
T8887 16673-16678 CD denotes 1.1.3
T8886 16671-16673 CC denotes v.
T8885 16670-16671 -LRB- denotes (
T8884 16664-16669 NNP denotes OMIGA
T8883 16656-16663 NN denotes program
T8882 16652-16655 DT denotes the
T8881 16646-16651 VBG denotes using
T8880 16644-16645 -RRB- denotes )
T8879 16643-16644 CD denotes 1
T8878 16637-16642 NNP denotes Table
T8877 16636-16637 -LRB- denotes (
T8876 16627-16635 NN denotes promoter
T8875 16620-16626 NN denotes IL-1RA
T8874 16616-16619 DT denotes the
T8873 16613-16615 IN denotes of
T8872 16607-16612 NNS denotes sites
T8871 16599-16606 JJ denotes binding
T8870 16592-16598 NN denotes factor
T8869 16578-16591 NN denotes transcription
T8868 16567-16577 VBN denotes discovered
T8867 16561-16566 RB denotes newly
T8866 16557-16560 CC denotes and
T8865 16547-16556 VBN denotes described
T8864 16536-16546 JJ denotes previoulsy
T8863 16523-16535 VBD denotes investigated
T8862 16520-16522 PRP denotes We
T8861 16518-16519 . denotes .
T8860 16510-16518 NN denotes promoter
T8859 16503-16509 NN denotes IL-1RA
T8858 16499-16502 DT denotes the
T8857 16496-16498 IN denotes in
T8856 16490-16495 NNS denotes sites
T8855 16487-16489 TO denotes to
T8854 16482-16486 NN denotes bind
T8853 16476-16481 MD denotes might
T8852 16468-16475 NNS denotes factors
T8851 16454-16467 NN denotes transcription
T8850 16444-16453 VBN denotes activated
T8849 16440-16443 DT denotes the
T8848 16435-16439 IN denotes that
T8847 16422-16434 VBD denotes hypothesized
T8846 16419-16421 PRP denotes we
T8845 16417-16418 , denotes ,
T8844 16413-16417 NNP denotes IFNγ
T8843 16410-16412 CC denotes or
T8842 16405-16409 NNP denotes IL-6
T8841 16403-16404 , denotes ,
T8840 16399-16403 NNP denotes TNFα
T8839 16396-16398 DT denotes no
T8838 16392-16395 CC denotes but
T8837 16390-16391 , denotes ,
T8836 16385-16390 NNS denotes sites
T8835 16380-16384 NNP denotes NFAT
T8834 16376-16379 CC denotes and
T8833 16369-16375 NNP denotes NFIL-6
T8832 16367-16368 , denotes ,
T8831 16363-16367 NNP denotes NFκB
T8830 16360-16362 TO denotes to
T8829 16353-16359 NNS denotes shifts
T8828 16348-16352 NN denotes band
T8827 16340-16347 VBD denotes induced
T8826 16337-16339 NNP denotes GP
T8825 16329-16336 IN denotes Because
T8824 16324-16328 NNP denotes PBMC
T8823 16318-16323 JJ denotes human
T8822 16315-16317 IN denotes by
T8821 16304-16314 NN denotes expression
T8820 16297-16303 NNP denotes IL-1RA
T8819 16282-16296 NNP denotes TSST-1-induced
T8818 16280-16281 NNP denotes +
T8817 16277-16279 NNP denotes GP
T8816 16273-16276 CC denotes and
T8815 16271-16272 : denotes -
T8814 16268-16271 NNP denotes LPS
T8813 16266-16267 NNP denotes +
T8812 16263-16265 NNP denotes GP
T8811 16261-16262 , denotes ,
T8810 16260-16261 : denotes -
T8809 16258-16260 NNP denotes GP
T8808 16256-16257 , denotes ,
T8807 16255-16256 : denotes -
T8806 16249-16255 NNP denotes TSST-1
T8805 16247-16248 , denotes ,
T8804 16246-16247 : denotes -
T8803 16243-16246 NNP denotes LPS
T8802 16240-16242 IN denotes in
T8801 16232-16239 JJ denotes binding
T8800 16227-16231 NNP denotes NFAT
T8799 16223-16226 CC denotes and
T8798 16216-16222 NNP denotes NFIL-6
T8797 16214-16215 , denotes ,
T8796 16210-16214 NNP denotes NFκB
T8795 16207-16209 IN denotes of
T8794 16202-16206 NN denotes Role
T9299 18505-18506 . denotes .
T9298 18504-18505 -RRB- denotes )
T9297 18503-18504 . denotes .
T9296 18499-18503 NN denotes calc
T9295 18498-18499 -LRB- denotes (
T9294 18491-18497 NNS denotes values
T9293 18479-18490 JJ denotes theoretical
T9292 18475-18478 DT denotes the
T9291 18470-18474 IN denotes from
T9290 18460-18469 JJ denotes different
T9289 18456-18459 RB denotes not
T9288 18451-18455 VBD denotes were
T9287 18443-18450 NNS denotes results
T9286 18430-18442 JJ denotes experimental
T9285 18426-18429 DT denotes the
T9284 18421-18425 FW denotes i.e.
T9283 18419-18420 , denotes ,
T9282 18413-18419 NN denotes manner
T9281 18401-18412 JJ denotes synergistic
T9280 18392-18400 JJ denotes additive
T9279 18389-18391 DT denotes an
T9278 18386-18388 IN denotes in
T9277 18381-18385 RB denotes only
T9276 18377-18380 CC denotes but
T9275 18375-18376 , denotes ,
T9274 18374-18375 -RRB- denotes )
T9273 18373-18374 CD denotes 5
T9272 18368-18372 NNP denotes Fig.
T9271 18366-18367 : denotes ;
T9270 18362-18366 CD denotes 0.05
T9269 18360-18361 NN denotes <
T9268 18358-18359 JJ denotes p
T9267 18357-18358 -LRB- denotes (
T9266 18348-18356 VBN denotes elevated
T9049 17414-17417 IN denotes for
T9048 17405-17413 VBN denotes elevated
T9047 17391-17404 RB denotes significantly
T9046 17387-17390 VBD denotes was
T9045 17385-17386 -RRB- denotes )
T9044 17381-17385 CD denotes -280
T9043 17377-17380 CC denotes and
T9042 17372-17376 CD denotes -266
T9041 17364-17371 IN denotes between
T9040 17363-17364 -LRB- denotes (
T9039 17358-17362 NN denotes site
T9038 17348-17357 NN denotes consensus
T9037 17345-17347 NN denotes κB
T9036 17341-17344 JJ denotes new
T9035 17339-17340 DT denotes a
T9034 17336-17338 TO denotes to
T9033 17328-17335 VBG denotes Binding
T9032 17326-17327 . denotes .
T9031 17325-17326 -RRB- denotes )
T9030 17324-17325 CD denotes 4
T9029 17319-17323 NNP denotes Fig.
T9028 17317-17318 : denotes ;
T9027 17313-17317 CD denotes 0.05
T9026 17311-17312 CD denotes <
T9025 17309-17310 VBP denotes p
T9024 17305-17308 DT denotes all
T9023 17304-17305 -LRB- denotes (
T9022 17302-17303 . denotes .
T9021 17298-17302 NN denotes calc
T9020 17295-17297 CD denotes -1
T9019 17288-17295 NNP denotes GP/TSST
T9018 17285-17287 CC denotes or
T9017 17283-17284 . denotes .
T9016 17279-17283 NN denotes calc
T9015 17272-17278 NNP denotes GP/LPS
T9014 17269-17271 IN denotes of
T9013 17262-17268 NNS denotes values
T9012 17250-17261 JJ denotes theoretical
T9011 17246-17249 DT denotes the
T9010 17243-17245 CC denotes or
T9009 17240-17242 NNP denotes GP
T9008 17237-17239 CC denotes or
T9007 17230-17236 CD denotes TSST-1
T9006 17228-17229 , denotes ,
T9005 17225-17228 NNP denotes LPS
T9004 17222-17224 TO denotes to
T9003 17219-17221 IN denotes as
T9002 17214-17218 RB denotes well
T9001 17211-17213 RB denotes as
T9000 17203-17210 NN denotes control
T8999 17196-17202 JJ denotes medium
T8998 17193-17195 TO denotes to
T8997 17184-17192 VBN denotes compared
T8996 17179-17183 WRB denotes when
T8995 17177-17178 , denotes ,
T8994 17170-17177 NN denotes fashion
T8993 17158-17169 JJ denotes synergistic
T8992 17144-17157 JJ denotes superadditive
T8991 17142-17143 DT denotes a
T8990 17139-17141 IN denotes in
T8989 17131-17138 JJ denotes binding
T8988 17123-17130 VBD denotes induced
T8987 17122-17123 : denotes -
T8986 17121-17122 -RRB- denotes )
T8985 17114-17121 NN denotes control
T8984 17110-17113 IN denotes vs.
T8983 17108-17109 NN denotes %
T8982 17104-17108 CD denotes +110
T8981 17103-17104 -LRB- denotes (
T8980 17096-17102 NNP denotes TSST-1
T8979 17092-17095 DT denotes the
T8978 17088-17091 CC denotes and
T8977 17086-17087 : denotes -
T8976 17085-17086 -RRB- denotes )
T8975 17078-17085 NN denotes control
T8974 17074-17077 IN denotes vs.
T8973 17072-17073 NN denotes %
T8972 17069-17072 CD denotes +65
T8971 17068-17069 -LRB- denotes (
T8970 17064-17067 NNP denotes LPS
T8969 17060-17063 DT denotes the
T8968 17047-17059 JJ denotes up-regulated
T8967 17034-17046 JJ denotes co-treatment
T8966 17031-17033 NNP denotes GP
T8965 17027-17030 CC denotes but
T8964 17025-17026 , denotes ,
T8963 17024-17025 -RRB- denotes )
T8962 17017-17024 NN denotes control
T8961 17013-17016 IN denotes vs.
T8960 17011-17012 NN denotes %
T8959 17008-17011 CD denotes +30
T8958 17007-17008 -LRB- denotes (
T8957 17000-17006 NNP denotes TSST-1
T8956 16997-16999 IN denotes by
T8955 16989-16996 VBN denotes induced
T8954 16981-16988 JJ denotes binding
T8953 16971-16980 VBN denotes increased
T8952 16964-16970 VBD denotes showed
T8951 16962-16963 NNP denotes ]
T8950 16960-16962 CD denotes 30
T8949 16959-16960 NNP denotes [
T8948 16953-16958 NNP denotes LRE-1
T8947 16949-16952 DT denotes the
T8946 16942-16948 IN denotes within
T8945 16940-16941 -RRB- denotes )
T8944 16936-16940 CD denotes -130
T8943 16932-16935 CC denotes and
T8942 16927-16931 CD denotes -100
T8941 16926-16927 -LRB- denotes (
T8940 16921-16925 NN denotes site
T8939 16917-16920 JJ denotes κB3
T8938 16913-16916 JJ denotes new
T8937 16911-16912 DT denotes A
T8936 16909-16910 . denotes .
T8935 16908-16909 -RRB- denotes )
T8934 16903-16908 VBN denotes shown
T8933 16899-16902 RB denotes not
T8932 16894-16898 NNS denotes data
T8931 16893-16894 -LRB- denotes (
T8930 16883-16892 NN denotes treatment
T8929 16879-16882 DT denotes the
T8928 16876-16878 IN denotes of
T8927 16863-16875 RB denotes irrespective
T8926 16861-16862 , denotes ,
T8925 16853-16861 NN denotes activity
T8924 16845-16852 JJ denotes binding
T8923 16841-16844 PRP$ denotes its
T8922 16838-16840 IN denotes of
T8921 16826-16837 NNS denotes alterations
T8920 16814-16825 JJ denotes significant
T8919 16811-16813 DT denotes no
T8918 16807-16810 CC denotes but
T8917 16805-16806 , denotes ,
T8916 16799-16805 NNS denotes shifts
T8915 16794-16798 NN denotes band
T8914 16784-16793 VBD denotes displayed
T7083 14684-14686 NNP denotes GP
T7414 16199-16200 . denotes .
T7413 16198-16199 -RRB- denotes )
T7412 16193-16198 VBN denotes shown
T7411 16189-16192 RB denotes not
T7410 16184-16188 NNS denotes data
T7409 16183-16184 -LRB- denotes (
T7408 16181-16182 NN denotes h
T7407 16178-16180 CD denotes 48
T7406 16173-16177 IN denotes over
T7405 16171-16172 . denotes .
T7404 16167-16171 NN denotes calc
T7273 15588-15589 -RRB- denotes )
T7272 15586-15588 FW denotes vi
T7271 15585-15586 -LRB- denotes (
T7270 15582-15583 . denotes .
T7269 15581-15582 -RRB- denotes )
T7268 15575-15581 NN denotes detail
T7267 15572-15574 IN denotes in
T7266 15566-15571 VBN denotes shown
T7265 15562-15565 RB denotes not
T7264 15557-15561 NNS denotes data
T7263 15555-15556 : denotes ;
T7262 15551-15555 CD denotes 0.05
T7261 15549-15550 NN denotes >
T7260 15547-15548 JJ denotes p
T7259 15546-15547 -LRB- denotes (
T7258 15537-15545 JJ denotes observed
T7257 15533-15536 VBD denotes was
T7256 15531-15532 NN denotes %
T7255 15529-15531 CD denotes 10
T7254 15524-15528 RB denotes only
T7253 15521-15523 IN denotes of
T7252 15509-15520 NN denotes enhancement
T7251 15506-15508 DT denotes an
T7250 15498-15505 RB denotes overall
T7249 15494-15497 CC denotes but
T7248 15492-15493 , denotes ,
T7247 15491-15492 -RRB- denotes )
T7246 15487-15491 CD denotes 0.05
T7245 15485-15486 RB denotes <
T7244 15483-15484 VB denotes p
T7243 15481-15482 : denotes ;
T7242 15480-15481 CD denotes 3
T7241 15478-15479 SYM denotes =
T7240 15476-15477 FW denotes n
T7239 15475-15476 -LRB- denotes (
T7238 15473-15474 NN denotes h
T7237 15470-15472 CD denotes 36
T7236 15464-15469 IN denotes after
T7235 15454-15463 NN denotes secretion
T7234 15449-15453 NNP denotes TNFα
T7233 15446-15448 IN denotes on
T7232 15439-15445 NN denotes effect
T7231 15427-15438 JJ denotes synergistic
T7230 15425-15426 DT denotes a
T7229 15419-15424 VB denotes exert
T7228 15416-15418 TO denotes to
T7227 15409-15415 VBD denotes seemed
T7226 15406-15408 NNP denotes GP
T7225 15404-15405 , denotes ,
T7224 15399-15404 NN denotes calc.
T7223 15396-15398 CD denotes -1
T7222 15389-15396 NNP denotes GP/TSST
T7221 15386-15388 CC denotes or
T7220 15379-15385 CD denotes TSST-1
T7219 15374-15378 IN denotes with
T7218 15365-15373 VBN denotes combined
T7217 15360-15364 WRB denotes When
T7216 15358-15359 . denotes .
T7215 15354-15358 NN denotes calc
T7214 15347-15353 NNP denotes GP/LPS
T7213 15344-15346 CC denotes or
T7212 15328-15343 NN denotes supplementation
T7211 15324-15327 NNP denotes LPS
T7210 15321-15323 TO denotes to
T7209 15312-15320 VBN denotes compared
T7208 15307-15311 WRB denotes when
T7207 15296-15306 NN denotes production
T7206 15291-15295 JJ denotes TNFα
T7205 15287-15290 DT denotes the
T7204 15280-15286 VB denotes change
T7203 15276-15279 RB denotes not
T7202 15272-15275 VBD denotes did
T7201 15268-15271 NNP denotes LPS
T7200 15266-15267 NNP denotes +
T7199 15263-15265 NNP denotes GP
T7198 15261-15262 . denotes .
T7197 15254-15261 NN denotes control
T7196 15247-15253 JJ denotes medium
T7195 15244-15246 TO denotes to
T7194 15235-15243 VBN denotes compared
T7193 15230-15234 WRB denotes when
T7192 15228-15229 , denotes ,
T7191 15221-15228 NNS denotes amounts
T7190 15205-15220 JJ denotes distinguishable
T7189 15201-15204 RB denotes not
T7188 15187-15200 RB denotes statistically
T7187 15185-15186 , denotes ,
T7186 15180-15185 JJ denotes minor
T7185 15172-15179 VBD denotes yielded
T7184 15169-15171 NNP denotes GP
T7183 15166-15168 IN denotes of
T7182 15163-15165 NN denotes μg
T7181 15159-15162 CD denotes 100
T7180 15157-15158 , denotes ,
T7179 15147-15157 NN denotes production
T7178 15142-15146 VB denotes TNFα
T7177 15139-15141 TO denotes to
T7176 15131-15138 NN denotes respect
T7175 15126-15130 IN denotes With
T7174 15121-15125 NNP denotes TNFα
T7173 15119-15120 -RRB- denotes )
T7172 15118-15119 FW denotes v
T7171 15117-15118 -LRB- denotes (
T7170 15114-15115 . denotes .
T7169 15113-15114 -RRB- denotes )
T7168 15101-15113 RB denotes respectively
T7167 15099-15100 , denotes ,
T7166 15095-15099 CD denotes 0.98
T7165 15091-15094 CC denotes and
T7164 15087-15090 CD denotes 0.9
T7163 15085-15086 SYM denotes =
T7162 15083-15084 NN denotes r
T7161 15081-15082 , denotes ,
T7160 15076-15081 CD denotes 0.002
T7159 15074-15075 NN denotes ≤
T7158 15072-15073 NN denotes p
T7157 15070-15071 , denotes ,
T7156 15069-15070 CD denotes 5
T7155 15067-15068 SYM denotes =
T7154 15065-15066 FW denotes n
T7153 15064-15065 -LRB- denotes (
T7152 15061-15063 NNP denotes GP
T7151 15058-15060 NN denotes μg
T7150 15056-15057 CD denotes 1
T7149 15051-15055 IN denotes than
T7148 15044-15050 NN denotes IL-1RA
T7147 15040-15043 CC denotes and
T7146 15035-15039 NN denotes IL-8
T7145 15032-15034 IN denotes of
T7144 15024-15031 NNS denotes amounts
T7143 15017-15023 JJR denotes larger
T7142 15009-15016 VBD denotes induced
T7141 15006-15008 NNP denotes GP
T7140 15003-15005 IN denotes of
T7139 15000-15002 NN denotes μg
T7138 14996-14999 CD denotes 100
T7137 14990-14995 IN denotes since
T7136 14988-14989 , denotes ,
T7135 14974-14988 JJ denotes dose-dependent
T7134 14971-14973 VB denotes be
T7133 14968-14970 TO denotes to
T7132 14956-14967 NN denotes correlation
T7131 14951-14955 DT denotes this
T7130 14945-14950 VBD denotes found
T7129 14942-14944 PRP denotes we
T7121 14895-14906 NN denotes correlation
T7120 14886-14894 JJ denotes positive
T7119 14884-14885 DT denotes a
T7118 14875-14883 VBD denotes observed
T7117 14872-14874 PRP denotes we
T7116 14870-14871 , denotes ,
T7115 14869-14870 -RRB- denotes )
T7114 14868-14869 NN denotes h
T7113 14865-14867 CD denotes 24
T7112 14864-14865 -LRB- denotes (
T7111 14861-14863 NNP denotes GP
T7110 14856-14860 IN denotes with
T7109 14844-14855 NN denotes stimulation
T7108 14834-14843 VBG denotes Following
T7107 14832-14833 . denotes .
T7106 14821-14832 NNS denotes productions
T7105 14814-14820 NN denotes IL-1RA
T7104 14810-14813 CC denotes and
T7103 14805-14809 NN denotes IL-8
T7102 14794-14804 JJ denotes GP-induced
T7101 14786-14793 IN denotes between
T7100 14774-14785 NN denotes correlation
T7099 14765-14773 JJ denotes Positive
T7098 14763-14764 . denotes .
T7097 14762-14763 -RRB- denotes )
T7096 14760-14762 NNP denotes 3B
T7095 14755-14759 NNP denotes Fig.
T7094 14754-14755 -LRB- denotes (
T7093 14752-14753 NN denotes %
T7092 14749-14752 CD denotes 200
T7091 14735-14748 RB denotes approximately
T7090 14732-14734 IN denotes by
T7089 14725-14731 NN denotes IL-1RA
T7088 14722-14724 IN denotes of
T7087 14715-14721 NN denotes amount
T7086 14700-14714 JJ denotes TSST-1-induced
T7085 14696-14699 DT denotes the
T7084 14687-14695 VBD denotes elevated
T7082 14682-14683 , denotes ,
T7081 14681-14682 NN denotes h
T7080 14678-14680 CD denotes 48
T7079 14675-14677 IN denotes of
T7078 14668-14674 NN denotes course
T7077 14663-14667 NN denotes time
T7076 14659-14662 DT denotes the
T7075 14654-14658 IN denotes Over
T7074 14652-14653 . denotes .
T7073 14651-14652 -RRB- denotes )
T7072 14650-14651 NN denotes h
T7071 14647-14649 CD denotes 36
T7070 14644-14646 TO denotes to
T7069 14642-14643 NN denotes h
T7068 14639-14641 CD denotes 18
T7067 14634-14638 IN denotes from
T7066 14633-14634 -LRB- denotes (
T7065 14631-14632 . denotes .
T7064 14627-14631 NN denotes calc
T7063 14624-14626 CD denotes -1
T7062 14617-14624 NNP denotes GP/TSST
T7061 14614-14616 IN denotes of
T7060 14608-14613 NN denotes value
T7059 14596-14607 JJ denotes theoretical
T7058 14592-14595 DT denotes the
T7049 14571-14572 SYM denotes =
T7048 14569-14570 VB denotes n
T7047 14567-14568 : denotes :
T7046 14566-14567 NN denotes h
T7045 14563-14565 CD denotes 24
T7044 14560-14562 IN denotes at
T7043 14551-14559 NN denotes instance
T7042 14547-14550 IN denotes for
T7041 14546-14547 -LRB- denotes (
T7040 14539-14545 NNP denotes TSST-1
T7039 14536-14538 TO denotes to
T7038 14527-14535 VBN denotes compared
T7037 14522-14526 WRB denotes when
T7036 14520-14521 , denotes ,
T7035 14519-14520 NN denotes h
T7034 14516-14518 CD denotes 48
T7033 14513-14515 TO denotes to
T7032 14511-14512 NN denotes h
T7031 14508-14510 CD denotes 18
T7030 14503-14507 IN denotes from
T7029 14492-14502 NN denotes production
T7028 14485-14491 NN denotes IL-1RA
T7027 14482-14484 IN denotes in
T7026 14473-14481 NN denotes increase
T7025 14461-14472 JJ denotes synergistic
T7024 14459-14460 DT denotes a
T7023 14453-14458 VBD denotes found
T7022 14450-14452 PRP denotes we
T7021 14443-14449 NNP denotes TSST-1
T7020 14441-14442 NNP denotes +
T7019 14438-14440 NNP denotes GP
T7018 14428-14437 VBG denotes following
T7017 14426-14427 , denotes ,
T7016 14419-14426 RB denotes However
T7015 14417-14418 . denotes .
T7014 14407-14417 NN denotes production
T7013 14400-14406 NN denotes IL-1RA
T7012 14396-14399 DT denotes the
T7011 14393-14395 IN denotes of
T7010 14386-14392 NN denotes course
T7009 14378-14385 JJ denotes kinetic
T7008 14374-14377 DT denotes the
T7007 14368-14373 VB denotes alter
T7006 14364-14367 RB denotes not
T7005 14360-14363 VBD denotes did
T7004 14356-14359 NNP denotes LPS
T7003 14354-14355 NNP denotes +
T7002 14351-14353 NNP denotes GP
T7001 14349-14350 , denotes ,
T7000 14344-14349 NNP denotes calc.
T6999 14337-14343 NNP denotes GP/LPS
T6998 14334-14336 CC denotes or
T6997 14322-14333 NN denotes stimulation
T6996 14318-14321 NNP denotes LPS
T6995 14315-14317 TO denotes to
T6994 14306-14314 VBN denotes compared
T6993 14301-14305 WRB denotes When
T6992 14299-14300 . denotes .
T6991 14298-14299 -RRB- denotes )
T6990 14294-14298 CD denotes 0.01
T6989 14292-14293 NN denotes <
T6988 14290-14291 NN denotes p
T6987 14288-14289 , denotes ,
T6986 14286-14288 CD denotes 14
T6985 14284-14285 SYM denotes =
T6984 14282-14283 FW denotes n
T6983 14281-14282 -LRB- denotes (
T6982 14279-14280 NN denotes h
T6981 14276-14278 CD denotes 24
T6980 14273-14275 IN denotes at
T6979 14262-14272 RB denotes especially
T6978 14260-14261 , denotes ,
T6977 14251-14260 NN denotes treatment
T6976 14248-14250 NNP denotes GP
T6975 14238-14247 VBG denotes following
T6974 14227-14237 NNS denotes quantities
T6973 14215-14226 JJ denotes significant
T6972 14212-14214 IN denotes in
T6971 14203-14211 VBN denotes produced
T6970 14199-14202 VBD denotes was
T6969 14193-14198 WDT denotes which
T6968 14184-14192 NN denotes mediator
T6967 14179-14183 JJ denotes only
T6966 14175-14178 DT denotes the
T6965 14171-14174 VBD denotes was
T6964 14164-14170 NNP denotes IL-1RA
T6963 14162-14163 , denotes ,
T6962 14158-14162 NNP denotes IL-8
T6961 14150-14157 IN denotes Besides
T6960 14143-14149 NNP denotes IL-1RA
T6959 14141-14142 -RRB- denotes )
T6958 14139-14141 FW denotes iv
T6957 14138-14139 -LRB- denotes (
T6956 14135-14136 . denotes .
T6955 14134-14135 -RRB- denotes )
T6954 14128-14134 NN denotes detail
T6953 14125-14127 IN denotes in
T6952 14119-14124 VBN denotes shown
T6951 14115-14118 RB denotes not
T6950 14110-14114 NNS denotes data
T6949 14109-14110 -LRB- denotes (
T6948 14107-14108 . denotes .
T6947 14103-14107 NN denotes calc
T6946 14100-14102 CD denotes -1
T6945 14093-14100 NNP denotes GP/TSST
T6944 14090-14092 CC denotes or
T6943 14083-14089 CD denotes TSST-1
T6942 14080-14082 TO denotes to
T6941 14071-14079 VBN denotes compared
T6940 14066-14070 WRB denotes when
T6939 14059-14065 NNP denotes TSST-1
T6938 14057-14058 NNP denotes +
T6937 14054-14056 NNP denotes GP
T6936 14044-14053 VBG denotes following
T6935 14033-14043 NN denotes production
T6934 14028-14032 JJ denotes IL-8
T6933 14025-14027 IN denotes in
T6932 14014-14024 NN denotes alteration
T6931 14002-14013 JJ denotes significant
T6930 13999-14001 DT denotes no
T6929 13995-13998 VBD denotes was
T6928 13989-13994 EX denotes There
T6927 13987-13988 . denotes .
T6926 13983-13987 NN denotes calc
T6925 13976-13982 NNP denotes GP/LPS
T6924 13973-13975 CC denotes or
T6923 13969-13972 NNP denotes LPS
T6922 13966-13968 TO denotes to
T6921 13957-13965 VBN denotes compared
T6920 13952-13956 WRB denotes when
T6919 13941-13951 NN denotes production
T6918 13936-13940 JJ denotes IL-8
T6917 13933-13935 IN denotes of
T6916 13924-13932 NN denotes increase
T6915 13908-13923 JJ denotes non-significant
T6914 13906-13907 DT denotes a
T6913 13903-13905 IN denotes in
T6912 13894-13902 VBD denotes resulted
T6911 13890-13893 NNP denotes LPS
T6910 13886-13889 CC denotes and
T6909 13883-13885 NNP denotes GP
T6908 13880-13882 IN denotes of
T6907 13868-13879 NN denotes combination
T6906 13866-13867 DT denotes A
T6905 13864-13865 . denotes .
T6904 13863-13864 -RRB- denotes )
T6903 13859-13863 CD denotes 0.01
T6902 13857-13858 NN denotes <
T6901 13855-13856 VB denotes p
T6900 13853-13854 : denotes ;
T6899 13851-13853 CD denotes 13
T6898 13849-13850 SYM denotes =
T6897 13847-13848 FW denotes n
T6896 13846-13847 -LRB- denotes (
T6895 13844-13845 NN denotes h
T6894 13841-13843 CD denotes 24
T6893 13838-13840 IN denotes at
T6892 13827-13837 RB denotes especially
T6891 13825-13826 , denotes ,
T6890 13818-13825 NN denotes control
T6889 13811-13817 JJ denotes medium
T6888 13806-13810 IN denotes with
T6887 13795-13805 NN denotes comparison
T6886 13792-13794 IN denotes in
T6885 13790-13791 , denotes ,
T6884 13780-13790 NN denotes production
T6883 13775-13779 NN denotes IL-8
T6882 13763-13774 JJ denotes substantial
T6881 13761-13762 DT denotes a
T6880 13753-13760 VBD denotes induced
T6879 13750-13752 NNP denotes GP
T6878 13745-13749 IN denotes that
T6877 13739-13744 VBD denotes found
T6876 13736-13738 PRP denotes We
T6875 13731-13735 NN denotes IL-8
T6874 13729-13730 -RRB- denotes )
T6873 13726-13729 FW denotes iii
T6872 13725-13726 -LRB- denotes (
T6871 13722-13723 . denotes .
T6870 13721-13722 -RRB- denotes )
T6869 13715-13721 NN denotes detail
T6868 13712-13714 IN denotes in
T6867 13706-13711 VBN denotes shown
T6866 13702-13705 RB denotes not
T6865 13697-13701 NNS denotes data
T6864 13696-13697 -LRB- denotes (
T6863 13694-13695 , denotes ,
T6862 13693-13694 -RRB- denotes )
T6861 13689-13693 CD denotes 0.02
T6860 13687-13688 SYM denotes =
T7403 16164-16166 CD denotes -1
T7402 16157-16164 NNP denotes GP/TSST
T7401 16154-16156 CC denotes or
T7400 16147-16153 NNP denotes TSST-1
T7399 16145-16146 NNP denotes +
T7398 16142-16144 NNP denotes GP
T7397 16138-16141 CC denotes and
T7396 16136-16137 . denotes .
T7395 16132-16136 NN denotes calc
T7394 16125-16131 NNP denotes GP/LPS
T7393 16123-16124 , denotes ,
T7392 16120-16123 NNP denotes LPS
T7391 16118-16119 NNP denotes +
T7390 16115-16117 NNP denotes GP
T7389 16113-16114 , denotes ,
T7388 16111-16113 NNP denotes GP
T7387 16109-16110 , denotes ,
T7386 16103-16109 NNP denotes TSST-1
T7385 16101-16102 , denotes ,
T7384 16098-16101 NNP denotes LPS
T7383 16096-16097 , denotes ,
T7382 16089-16096 NN denotes control
T7381 16082-16088 JJ denotes medium
T7380 16074-16081 IN denotes between
T7379 16062-16073 NNS denotes differences
T7378 16050-16061 JJ denotes significant
T7377 16047-16049 DT denotes no
T7376 16042-16046 RB denotes also
T7375 16037-16041 VBD denotes were
T7374 16031-16036 EX denotes There
T7373 16029-16030 . denotes .
T7372 16027-16029 NNP denotes GP
T7371 16024-16026 IN denotes by
T7370 16016-16023 VBN denotes induced
T7369 16012-16015 RB denotes not
T7368 16008-16011 VBD denotes was
T7367 16006-16007 CD denotes 1
T7366 16001-16005 NNP denotes TGFβ
T7365 15997-16000 CC denotes and
T7364 15991-15996 NNP denotes IL-10
T7363 15989-15990 , denotes ,
T7362 15985-15989 NN denotes IL-4
T7361 15983-15984 , denotes ,
T7360 15978-15983 NN denotes IL-12
T7359 15976-15977 , denotes ,
T7358 15972-15976 NN denotes IL-2
T7357 15969-15971 IN denotes of
T7356 15958-15968 NN denotes production
T7355 15954-15957 DT denotes The
T7354 15948-15953 NNP denotes TGFβ1
T7353 15946-15947 , denotes ,
T7352 15941-15946 NNP denotes IL-10
T7351 15939-15940 , denotes ,
T7350 15935-15939 NN denotes IL-4
T7349 15933-15934 , denotes ,
T7348 15928-15933 NN denotes IL-12
T7347 15926-15927 , denotes ,
T7346 15922-15926 NN denotes IL-2
T7345 15920-15921 -RRB- denotes )
T7344 15917-15920 FW denotes vii
T7343 15916-15917 -LRB- denotes (
T7342 15913-15914 . denotes .
T7341 15912-15913 -RRB- denotes )
T7340 15907-15912 VBN denotes shown
T7339 15903-15906 RB denotes not
T7338 15898-15902 NNS denotes data
T7337 15897-15898 -LRB- denotes (
T7336 15895-15896 . denotes .
T7335 15891-15895 NN denotes calc
T7334 15888-15890 CD denotes -1
T7333 15881-15888 NNP denotes GP/TSST
T7332 15878-15880 CC denotes or
T7331 15871-15877 CD denotes TSST-1
T7330 15868-15870 TO denotes to
T7329 15859-15867 VBN denotes compared
T7328 15854-15858 WRB denotes when
T7322 15839-15841 CD denotes 24
T7321 15836-15838 IN denotes at
T7320 15829-15835 NNP denotes TSST-1
T7319 15827-15828 NNP denotes +
T7318 15824-15826 NNP denotes GP
T7317 15814-15823 VBG denotes following
T7316 15798-15813 NN denotes down-regulation
T7315 15791-15797 JJ denotes slight
T7314 15789-15790 DT denotes a
T7313 15785-15788 CC denotes and
T7312 15783-15784 , denotes ,
T7311 15778-15783 NNP denotes calc.
T7310 15771-15777 NNP denotes GP/LPS
T7309 15768-15770 CC denotes or
T7308 15764-15767 NNP denotes LPS
T7307 15761-15763 TO denotes to
T7306 15752-15760 VBN denotes compared
T7305 15747-15751 WRB denotes when
T7304 15745-15746 , denotes ,
T7303 15744-15745 NN denotes h
T7302 15741-15743 CD denotes 36
T7301 15738-15740 IN denotes at
T7300 15734-15737 NNP denotes LPS
T7299 15732-15733 NNP denotes +
T7298 15729-15731 NNP denotes GP
T7297 15719-15728 VBG denotes following
T7296 15708-15718 NN denotes production
T7295 15703-15707 JJ denotes IFNγ
T7294 15700-15702 IN denotes in
T7293 15691-15699 NN denotes increase
T7292 15685-15690 JJ denotes minor
T7291 15683-15684 DT denotes a
T7290 15679-15682 VBD denotes was
T7289 15673-15678 EX denotes There
T7288 15671-15672 . denotes .
T7287 15669-15671 NNP denotes GP
T7286 15666-15668 NN denotes μg
T7285 15662-15665 CD denotes 100
T7284 15657-15661 IN denotes with
T7283 15652-15656 NNP denotes PBMC
T7282 15649-15651 IN denotes of
T7281 15639-15648 NN denotes treatment
T7280 15629-15638 VBG denotes following
T7279 15618-15628 JJ denotes detectable
T7278 15614-15617 VBD denotes was
T7277 15603-15613 NN denotes production
T7276 15598-15602 NNP denotes IFNγ
T7275 15595-15597 NNP denotes No
T7274 15590-15594 NNP denotes IFNγ
T6859 13685-13686 VBP denotes p
T6858 13680-13684 DT denotes both
T6857 13678-13679 : denotes ;
T6856 13677-13678 CD denotes 5
T6855 13675-13676 SYM denotes =
T6854 13673-13674 FW denotes n
T6853 13672-13673 -LRB- denotes (
T6852 13670-13671 NN denotes %
T6851 13668-13670 CD denotes 40
T6850 13662-13667 RB denotes about
T6849 13659-13661 IN denotes by
T6848 13657-13658 NN denotes h
T6847 13654-13656 CD denotes 24
T6846 13651-13653 IN denotes at
T6845 13640-13650 RB denotes especially
T6844 13638-13639 , denotes ,
T6843 13633-13638 NN denotes calc.
T6842 13630-13632 CD denotes -1
T6841 13623-13630 NNP denotes GP/TSST
T6840 13620-13622 CC denotes or
T6839 13613-13619 CD denotes TSST-1
T6838 13610-13612 TO denotes to
T6837 13601-13609 VBN denotes compared
T6836 13596-13600 WRB denotes when
T6835 13589-13595 NNP denotes TSST-1
T6834 13587-13588 NNP denotes +
T6645 11409-11412 CC denotes and
T6644 11407-11408 -RRB- denotes )
T6643 11406-11407 NN denotes h
T6642 11403-11405 CD denotes 48
T6641 11402-11403 -LRB- denotes (
T6640 11397-11401 NN denotes time
T6639 11392-11396 IN denotes over
T6638 11382-11391 NNS denotes cytokines
T6637 11369-11381 JJ denotes inflammatory
T6636 11367-11368 -RRB- denotes )
T6635 11362-11367 CD denotes three
T6634 11361-11362 -LRB- denotes (
T6633 11355-11360 JJ denotes anti-
T6632 11352-11354 IN denotes as
T6631 11347-11351 RB denotes well
T6630 11344-11346 RB denotes as
T6629 11342-11343 -RRB- denotes )
T6628 11337-11342 CD denotes eight
T6627 11336-11337 -LRB- denotes (
T6626 11331-11335 JJ denotes pro-
T6625 11321-11330 VBG denotes examining
T6624 11318-11320 IN denotes of
T6623 11312-11317 NNS denotes terms
T6622 11309-11311 IN denotes in
T6621 11300-11308 NNS denotes findings
T6620 11291-11299 JJ denotes singular
T6619 11285-11290 DT denotes these
T6618 11275-11284 VBG denotes extending
T6617 11271-11274 CC denotes and
T6616 11257-11270 VBG denotes Corroborating
T6615 11255-11256 . denotes .
T6614 11254-11255 NNP denotes ]
T6613 11249-11254 CD denotes 15-18
T6612 11248-11249 NNP denotes [
T6611 11242-11247 NNS denotes cells
T6610 11236-11241 NN denotes blood
T6609 11230-11235 JJ denotes human
T6608 11227-11229 IN denotes of
T6607 11217-11226 NN denotes secretion
T6606 11208-11216 NN denotes cytokine
T6605 11200-11207 JJ denotes limited
T6604 11198-11199 DT denotes a
T6603 11193-11197 RB denotes only
T6602 11185-11192 VBD denotes induced
T6601 11173-11184 NNS denotes 3-D-glucans
T6600 11172-11173 NN denotes →
T6599 11169-11172 JJ denotes β-1
T6598 11164-11168 IN denotes that
T6597 11155-11163 VBD denotes reported
T6596 11147-11154 NNS denotes studies
T6595 11138-11146 JJ denotes Previous
T6594 11136-11137 . denotes .
T6593 11127-11136 NNS denotes mediators
T6592 11110-11126 JJ denotes pro-inflammatory
T6591 11104-11109 JJ denotes other
T6590 11100-11103 CC denotes and
T6589 11095-11099 NNP denotes IFNγ
T6588 11093-11094 , denotes ,
T6587 11089-11093 NNP denotes IL-6
T6586 11087-11088 , denotes ,
T6585 11083-11087 NNP denotes IL-8
T6584 11081-11082 , denotes ,
T6583 11077-11081 NNP denotes TNFα
T6582 11074-11076 IN denotes of
T6581 11063-11073 NN denotes production
T6580 11060-11062 TO denotes to
T6579 11055-11059 VB denotes lead
T6578 11049-11054 MD denotes would
T6577 11044-11048 NNP denotes PBMC
T6576 11038-11043 JJ denotes human
T6575 11035-11037 IN denotes of
T6574 11025-11034 NN denotes treatment
T6573 11022-11024 NNP denotes GP
T6572 11017-11021 IN denotes that
T6571 11009-11016 VBN denotes assumed
T6570 11006-11008 VB denotes be
T6569 11000-11005 MD denotes could
T6568 10997-10999 PRP denotes it
T6567 10995-10996 , denotes ,
T6566 10986-10995 NNS denotes promoters
T6565 10981-10985 NNP denotes IFNγ
T6564 10977-10980 CC denotes and
T6563 10972-10976 NNP denotes IL-6
T6562 10970-10971 , denotes ,
T6561 10966-10970 NNP denotes IL-8
T6560 10964-10965 , denotes ,
T6559 10960-10964 NNP denotes TNFα
T6558 10956-10959 DT denotes the
T6557 10951-10955 IN denotes from
T6556 10945-10950 NNS denotes sites
T6555 10939-10944 CD denotes seven
T6554 10936-10938 TO denotes to
T6553 10929-10935 NNS denotes shifts
T6552 10924-10928 NN denotes band
T6551 10913-10923 JJ denotes GP-induced
T6550 10909-10912 DT denotes the
T6549 10906-10908 IN denotes of
T6548 10898-10905 IN denotes Because
T6547 10891-10897 NNP denotes TSST-1
T6546 10889-10890 NNP denotes +
T6545 10886-10888 NNP denotes GP
T6544 10882-10885 CC denotes and
T6543 10878-10881 NNP denotes LPS
T6542 10876-10877 NNP denotes +
T6541 10873-10875 NNP denotes GP
T6540 10871-10872 , denotes ,
T6539 10869-10871 NNP denotes GP
T6538 10867-10868 , denotes ,
T6537 10861-10867 NNP denotes TSST-1
T6536 10859-10860 , denotes ,
T6535 10856-10859 NNP denotes LPS
T6534 10851-10855 IN denotes with
T6533 10839-10850 NN denotes stimulation
T6532 10833-10838 NN denotes vitro
T6531 10830-10832 IN denotes in
T6530 10828-10829 NN denotes h
T6529 10825-10827 CD denotes 48
T6528 10823-10824 DT denotes a
T6527 10813-10822 VBG denotes following
T6526 10808-10812 NNP denotes PBMC
T6525 10802-10807 JJ denotes human
T6524 10799-10801 IN denotes of
T6523 10791-10798 NN denotes profile
T6522 10782-10790 NNP denotes Cytokine
T7057 14589-14591 TO denotes to
T7056 14586-14588 CC denotes or
T7055 14584-14585 -RRB- denotes )
T7054 14580-14584 CD denotes 0.01
T7053 14578-14579 SYM denotes =
T7052 14576-14577 VB denotes p
T7051 14574-14575 : denotes ;
T7050 14573-14574 CD denotes 6
T6833 13584-13586 NNP denotes GP
T6832 13580-13583 IN denotes for
T6831 13569-13579 NN denotes production
T6830 13564-13568 NN denotes IL-6
T6829 13554-13563 VBN denotes decreased
T6828 13552-13553 DT denotes a
T6827 13543-13551 VBD denotes observed
T6826 13540-13542 PRP denotes we
T6825 13538-13539 , denotes ,
T6824 13530-13538 NN denotes contrary
T6823 13526-13529 DT denotes the
T6822 13523-13525 IN denotes On
T6821 13521-13522 . denotes .
T6820 13519-13521 NNP denotes GP
T6819 13516-13518 IN denotes by
T6818 13505-13515 NN denotes production
T6817 13500-13504 NN denotes IL-6
T6816 13488-13499 JJ denotes LPS-induced
T6815 13484-13487 DT denotes the
T6814 13481-13483 IN denotes of
T6813 13470-13480 NN denotes alteration
T6812 13458-13469 JJ denotes significant
T6811 13455-13457 DT denotes no
T6810 13451-13454 VBD denotes was
T6809 13445-13450 EX denotes there
T6808 13441-13444 CC denotes and
T6807 13436-13440 NN denotes IL-6
T6806 13433-13435 IN denotes of
T6805 13426-13432 NN denotes amount
T6804 13420-13425 JJ denotes small
T6803 13418-13419 DT denotes a
T6802 13413-13417 RB denotes only
T6801 13405-13412 VBD denotes induced
T6800 13402-13404 NNP denotes GP
T6799 13397-13401 NN denotes IL-6
T6798 13395-13396 -RRB- denotes )
T6797 13393-13395 FW denotes ii
T6796 13392-13393 -LRB- denotes (
T6795 12174-12175 . denotes .
T6794 12173-12174 -RRB- denotes )
T6793 12171-12173 NNP denotes 3A
T6792 12166-12170 NNP denotes Fig.
T6791 12165-12166 -LRB- denotes (
T6790 12163-12164 NN denotes %
T6789 12161-12163 CD denotes 50
T6788 12155-12160 IN denotes about
T6787 12152-12154 IN denotes by
T6786 12146-12151 NN denotes IL-1β
T6785 12143-12145 IN denotes of
T6784 12136-12142 NN denotes amount
T6783 12121-12135 JJ denotes TSST-1-induced
T6782 12117-12120 DT denotes the
T6781 12114-12116 IN denotes of
T6780 12104-12113 NN denotes reduction
T6779 12102-12103 DT denotes a
T6778 12093-12101 VBD denotes mediated
T6777 12090-12092 NNP denotes GP
T6776 12088-12089 , denotes ,
T6775 12083-12088 NN denotes whole
T6774 12079-12082 DT denotes the
T6773 12076-12078 IN denotes On
T6772 12074-12075 . denotes .
T6771 12073-12074 -RRB- denotes )
T6770 12069-12073 CD denotes 0.01
T6769 12067-12068 SYM denotes =
T6768 12065-12066 VBP denotes p
T6767 12060-12064 DT denotes both
T6766 12058-12059 : denotes ;
T6765 12057-12058 CD denotes 6
T6764 12055-12056 SYM denotes =
T6763 12053-12054 FW denotes n
T6762 12052-12053 -LRB- denotes (
T6761 12050-12051 . denotes .
T6760 12046-12050 NN denotes calc
T6759 12043-12045 CD denotes -1
T6758 12036-12043 NNP denotes GP/TSST
T6757 12033-12035 IN denotes of
T6756 12027-12032 NN denotes value
T6755 12015-12026 JJ denotes theoretical
T6754 12011-12014 DT denotes the
T6753 12008-12010 CC denotes or
T6752 12001-12007 CD denotes TSST-1
T6751 11998-12000 TO denotes to
T6750 11989-11997 VBN denotes compared
T6749 11984-11988 WRB denotes when
T6748 11982-11983 NN denotes %
T6747 11980-11982 CD denotes 40
T6746 11974-11979 IN denotes about
T6745 11971-11973 IN denotes by
T6744 11964-11970 JJ denotes latter
T6743 11960-11963 DT denotes the
T6742 11956-11959 IN denotes for
T6741 11954-11955 , denotes ,
T6740 11953-11954 NN denotes h
T6739 11950-11952 CD denotes 24
T6738 11946-11947 NN denotes h
T6737 11943-11945 CD denotes 18
T6736 11938-11942 IN denotes from
T6735 11932-11937 NN denotes IL-1β
T6734 11929-11931 IN denotes in
T6733 11919-11928 NN denotes reduction
T6732 11907-11918 JJ denotes significant
T6731 11905-11906 DT denotes a
T6730 11899-11904 VBD denotes found
T6729 11896-11898 PRP denotes we
T6728 11889-11895 NNP denotes TSST-1
T6727 11887-11888 NNP denotes +
T6726 11884-11886 NNP denotes GP
T6725 11880-11883 IN denotes For
T6724 11878-11879 . denotes .
T6723 11875-11878 NNP denotes LPS
T6722 11870-11874 IN denotes with
T6721 11859-11869 NN denotes comparison
T6720 11856-11858 IN denotes in
T6719 11847-11855 VBN denotes observed
T6718 11843-11846 VBD denotes was
T6717 11839-11842 NNP denotes LPS
T6716 11837-11838 NNP denotes +
T6715 11834-11836 NNP denotes GP
T6714 11830-11833 IN denotes for
T6713 11819-11829 NN denotes production
T6712 11813-11818 JJ denotes IL-1β
T6711 11810-11812 IN denotes of
T6710 11796-11809 NN denotes up-regulation
T6709 11782-11795 JJ denotes insignificant
T6708 11779-11781 DT denotes An
T6707 11777-11778 . denotes .
T6706 11775-11777 NNP denotes GP
T6705 11772-11774 NN denotes μg
T6704 11768-11771 CD denotes 100
T6703 11764-11767 CC denotes nor
T6702 11762-11763 CD denotes 1
T6701 11757-11761 IN denotes with
T6700 11747-11756 NN denotes treatment
T6699 11742-11746 NNP denotes PBMC
T6698 11732-11741 VBG denotes following
T6697 11721-11731 JJ denotes detectable
T6696 11710-11720 NN denotes production
T6695 11704-11709 JJ denotes IL-1β
T6694 11701-11703 DT denotes no
T6693 11697-11700 VBD denotes was
T6692 11691-11696 EX denotes There
T6691 11685-11690 JJ denotes IL-1β
T6690 11683-11684 -RRB- denotes )
T6689 11682-11683 FW denotes i
T6688 11681-11682 -LRB- denotes (
T6687 11678-11679 : denotes :
T6686 11677-11678 -RRB- denotes )
T6685 11671-11677 NNP denotes TSST-1
T6684 11669-11670 , denotes ,
T6683 11666-11669 NNP denotes LPS
T6682 11665-11666 -LRB- denotes (
T6681 11655-11664 NNS denotes mediators
T6680 11638-11654 JJ denotes pro-inflammatory
T6679 11634-11637 CD denotes two
T6678 11631-11633 TO denotes to
T6677 11620-11630 NN denotes comparison
T6676 11617-11619 IN denotes in
T6675 11613-11616 CC denotes and
T6674 11602-11612 NN denotes 3-D-glucan
T6673 11601-11602 NN denotes →
T6672 11598-11601 JJ denotes β-1
T6671 11590-11597 JJ denotes soluble
T6670 11584-11589 NN denotes water
T6669 11575-11583 VBN denotes purified
T6668 11568-11574 RB denotes highly
T6667 11566-11567 DT denotes a
T6666 11563-11565 TO denotes to
T6665 11554-11562 NN denotes response
T6664 11551-11553 IN denotes in
T6663 11540-11550 NNS denotes leukocytes
T6662 11534-11539 JJ denotes human
T6661 11531-11533 IN denotes of
T6660 11523-11530 NN denotes profile
T6659 11514-11522 NN denotes cytokine
T6658 11504-11513 JJ denotes following
T6657 11500-11503 DT denotes the
T6656 11491-11499 VBD denotes revealed
T6655 11482-11490 NN denotes analysis
T6654 11468-11481 JJ denotes comprehensive
T6653 11464-11467 PRP$ denotes our
T6652 11462-11463 , denotes ,
T6651 11457-11462 NNS denotes sites
T6650 11449-11456 JJ denotes binding
T6649 11442-11448 NN denotes factor
T6648 11428-11441 NN denotes transcription
T6647 11417-11427 JJ denotes additional
T6646 11413-11416 CD denotes six
T2109 2268-2271 JJ denotes β-1
T2110 2271-2272 NN denotes →
T2111 2272-2283 NNS denotes 3-D-glucans
T2112 2284-2289 VBP denotes occur
T2113 2290-2292 IN denotes as
T2114 2293-2294 DT denotes a
T2115 2295-2304 JJ denotes principal
T2116 2305-2314 NN denotes component
T2117 2315-2317 IN denotes of
T2118 2318-2327 JJ denotes microbial
T2119 2328-2332 NN denotes cell
T2120 2333-2338 NNS denotes walls
T2121 2339-2341 CC denotes or
T2122 2342-2345 MD denotes can
T2123 2346-2348 VB denotes be
T2124 2349-2357 VBN denotes secreted
T2125 2358-2362 IN denotes from
T2126 2363-2367 DT denotes both
T2127 2367-2368 , denotes ,
T2128 2369-2383 JJ denotes non-pathogenic
T2129 2384-2387 CC denotes and
T2130 2388-2398 JJ denotes pathogenic
T2131 2399-2404 NNS denotes fungi
T2132 2405-2409 JJ denotes such
T2133 2410-2412 IN denotes as
T2134 2413-2415 NNP denotes S.
T2135 2416-2425 NN denotes cerevisae
T2136 2426-2429 CC denotes and
T2137 2430-2432 NNP denotes C.
T2138 2433-2441 VBZ denotes albicans
T2139 2442-2443 NNP denotes [
T2140 2443-2444 CD denotes 1
T2141 2444-2445 NNP denotes ]
T2142 2445-2446 . denotes .
T2143 2447-2452 DT denotes These
T2144 2453-2456 JJ denotes β-1
T2145 2456-2457 NN denotes →
T2146 2457-2467 JJ denotes 3-D-linked
T2147 2468-2475 NN denotes glucose
T2148 2476-2484 NNS denotes polymers
T2149 2485-2488 VBP denotes are
T2150 2489-2502 VBN denotes characterized
T2151 2503-2505 IN denotes as
T2152 2506-2507 DT denotes a
T2153 2508-2514 JJ denotes fungal
T2154 2515-2534 JJ denotes pathogen-associated
T2155 2535-2544 JJ denotes molecular
T2156 2545-2552 NN denotes pattern
T2157 2553-2554 -LRB- denotes (
T2158 2554-2558 NNP denotes PAMP
T2159 2558-2559 -RRB- denotes )
T2160 2560-2561 NNP denotes [
T2161 2561-2562 CD denotes 2
T2162 2562-2563 NNP denotes ]
T2163 2563-2564 . denotes .
T2164 2565-2568 DT denotes The
T2165 2569-2576 JJ denotes primary
T2166 2577-2585 JJ denotes cellular
T2167 2586-2597 NN denotes recognition
T2168 2598-2600 IN denotes of
T2169 2601-2604 JJ denotes β-1
T2170 2604-2605 NN denotes →
T2171 2605-2616 NNS denotes 3-D-glucans
T2172 2617-2619 VBZ denotes is
T2173 2620-2628 VBN denotes mediated
T2174 2629-2631 IN denotes by
T2175 2632-2639 JJ denotes several
T2176 2640-2643 JJ denotes β-1
T2177 2643-2644 NN denotes →
T2178 2644-2654 JJ denotes 3-D-glucan
T2179 2655-2664 NNS denotes receptors
T2180 2665-2667 IN denotes on
T2181 2668-2678 NNS denotes phagocytes
T2182 2679-2680 NNP denotes [
T2183 2680-2683 CD denotes 3,4
T2184 2683-2684 NNP denotes ]
T2185 2685-2688 CC denotes and
T2186 2689-2694 JJ denotes other
T2187 2695-2700 NNS denotes cells
T2188 2701-2702 NNP denotes [
T2189 2702-2705 CD denotes 5,6
T2190 2705-2706 NNP denotes ]
T2191 2706-2707 . denotes .
T2192 2708-2713 NNP denotes Human
T2193 2714-2716 RB denotes as
T2194 2717-2721 RB denotes well
T2195 2722-2724 IN denotes as
T2196 2725-2731 JJ denotes murine
T2197 2732-2740 NN denotes Dectin-1
T2198 2741-2744 VBZ denotes has
T2199 2745-2749 VBN denotes been
T2200 2750-2762 VBN denotes demonstrated
T2201 2763-2765 TO denotes to
T2202 2766-2768 VB denotes be
T2203 2769-2772 DT denotes the
T2204 2773-2778 JJ denotes major
T2205 2779-2786 NN denotes pattern
T2206 2787-2798 NN denotes recognition
T2207 2799-2807 NN denotes receptor
T2208 2808-2809 -LRB- denotes (
T2209 2809-2812 NNP denotes PRR
T2210 2812-2813 -RRB- denotes )
T2211 2814-2817 IN denotes for
T2212 2818-2824 JJ denotes intact
T2213 2825-2830 NN denotes yeast
T2214 2831-2834 CC denotes and
T2215 2835-2838 JJ denotes β-1
T2216 2838-2839 NN denotes →
T2217 2839-2860 NN denotes 3-D-glucan-containing
T2218 2861-2870 NNS denotes particles
T2219 2871-2872 -LRB- denotes (
T2220 2872-2876 FW denotes i.e.
T2221 2877-2884 FW denotes zymosan
T2222 2884-2885 -RRB- denotes )
T2223 2886-2888 IN denotes on
T2224 2889-2910 NNS denotes monocytes/macrophages
T2225 2911-2913 RB denotes as
T2226 2914-2918 RB denotes well
T2227 2919-2921 IN denotes as
T2228 2922-2933 NNS denotes neutrophils
T2229 2934-2937 CC denotes and
T2230 2938-2940 IN denotes on
T2231 2941-2948 JJ denotes primary
T2232 2949-2954 NNS denotes cells
T2233 2955-2956 NNP denotes [
T2234 2956-2960 CD denotes 7-11
T2235 2960-2961 NNP denotes ]
T2236 2961-2962 . denotes .
T2237 2963-2965 IN denotes In
T2238 2966-2969 DT denotes the
T2239 2970-2976 NN denotes murine
T2240 2977-2983 NN denotes system
T2241 2983-2984 , denotes ,
T2242 2985-2992 JJ denotes binding
T2243 2993-2995 IN denotes of
T2244 2996-3003 NN denotes zymosan
T2245 3004-3006 TO denotes to
T2246 3007-3015 JJ denotes Dectin-1
T2247 3016-3024 VBD denotes resulted
T2248 3025-3027 IN denotes in
T2249 3028-3038 NN denotes production
T2250 3039-3041 IN denotes of
T2251 3042-3046 NNP denotes TNFα
T2252 3047-3054 IN denotes through
T2253 3055-3064 JJ denotes Toll-like
T2254 3065-3073 NN denotes receptor
T2255 3074-3075 CD denotes 2
T2256 3076-3079 CC denotes and
T2257 3080-3083 DT denotes the
T2258 3084-3091 NN denotes adaptor
T2259 3092-3099 NN denotes protein
T2260 3100-3105 NNP denotes MyD88
T2261 3106-3107 NNP denotes [
T2262 3107-3109 CD denotes 12
T2263 3109-3110 NNP denotes ]
T2264 3110-3111 . denotes .
T2265 3112-3119 DT denotes Another
T2266 3120-3133 JJ denotes water-soluble
T2267 3134-3137 JJ denotes β-1
T2268 3137-3138 NN denotes →
T2269 3138-3148 NN denotes 3-D-glucan
T2270 3149-3150 -LRB- denotes (
T2271 3150-3160 JJ denotes PGG-glucan
T2272 3160-3161 -RRB- denotes )
T2273 3162-3165 VBZ denotes has
T2274 3166-3170 VBN denotes been
T2275 3171-3180 VBN denotes described
T2276 3181-3183 TO denotes to
T2277 3184-3192 VB denotes activate
T2278 3193-3197 NNP denotes NFκB
T2279 3198-3201 CC denotes and
T2280 3202-3208 NNP denotes NFIL-6
T2281 3209-3211 IN denotes in
T2282 3212-3218 JJ denotes murine
T2283 3219-3223 NN denotes cell
T2284 3224-3229 NNS denotes lines
T2285 3230-3231 NNP denotes [
T2286 3231-3236 CD denotes 13,14
T2287 3236-3237 NNP denotes ]
T2288 3237-3238 . denotes .
T2289 3239-3248 RB denotes Similarly
T2290 3248-3249 , denotes ,
T2291 3250-3252 PRP denotes it
T2292 3253-3256 VBZ denotes has
T2293 3257-3261 VBN denotes been
T2294 3262-3267 VBN denotes shown
T2295 3268-3272 IN denotes that
T2296 3273-3276 JJ denotes β-1
T2297 3276-3277 NN denotes →
T2298 3277-3288 NNS denotes 3-D-glucans
T2299 3289-3297 VBP denotes activate
T2300 3298-3302 NNP denotes NFκB
T2301 3303-3305 IN denotes in
T2302 3306-3307 DT denotes a
T2303 3308-3313 JJ denotes human
T2304 3314-3327 JJ denotes monocyte-like
T2305 3328-3332 NN denotes cell
T2306 3333-3337 NN denotes line
T2307 3338-3339 NNP denotes [
T2308 3339-3341 CD denotes 15
T2309 3341-3342 NNP denotes ]
T2310 3343-3346 CC denotes and
T2311 3347-3349 IN denotes in
T2312 3350-3355 JJ denotes human
T2313 3356-3373 NN denotes polymorphonuclear
T2314 3374-3385 NNS denotes neutrophils
T2315 3386-3387 -LRB- denotes (
T2316 3387-3390 NNP denotes PMN
T2317 3390-3391 -RRB- denotes )
T2318 3391-3392 , denotes ,
T2319 3393-3395 IN denotes in
T2320 3396-3399 DT denotes the
T2321 3400-3406 JJ denotes latter
T2322 3407-3411 NN denotes case
T2323 3412-3419 IN denotes without
T2324 3420-3429 NN denotes secretion
T2325 3430-3432 IN denotes of
T2326 3433-3449 JJ denotes pro-inflammatory
T2327 3450-3459 NNS denotes cytokines
T2328 3460-3461 -LRB- denotes (
T2329 3461-3465 NN denotes IL-1
T2330 3465-3466 , denotes ,
T2331 3467-3471 NNP denotes IL-6
T2332 3471-3472 , denotes ,
T2333 3473-3477 NNP denotes TNFα
T2334 3477-3478 -RRB- denotes )
T2335 3479-3480 NNP denotes [
T2336 3480-3482 CD denotes 16
T2337 3482-3483 NNP denotes ]
T2338 3483-3484 . denotes .
T2339 3485-3488 CD denotes One
T2340 3489-3494 NN denotes study
T2341 3495-3503 VBD denotes proposed
T2342 3504-3508 IN denotes that
T2343 3509-3512 DT denotes the
T2344 3513-3523 NN denotes production
T2345 3524-3526 IN denotes of
T2346 3527-3530 DT denotes the
T2347 3531-3548 JJ denotes anti-inflammatory
T2348 3549-3555 NN denotes IL-1RA
T2349 3555-3556 , denotes ,
T2350 3557-3560 CC denotes but
T2351 3561-3564 RB denotes not
T2352 3565-3569 JJ denotes IL-1
T2353 3570-3572 IN denotes by
T2354 3573-3578 JJ denotes human
T2355 3579-3588 NNS denotes monocytes
T2356 3589-3592 MD denotes may
T2357 3593-3595 VB denotes be
T2358 3596-3597 DT denotes a
T2359 3598-3609 RB denotes potentially
T2360 3610-3620 JJ denotes protective
T2361 3621-3630 NN denotes mechanism
T2362 3631-3638 VBN denotes induced
T2363 3639-3641 IN denotes by
T2364 3642-3645 JJ denotes β-1
T2365 3645-3646 NN denotes →
T2366 3646-3656 JJ denotes 3-D-glucan
T2367 3657-3658 NNP denotes [
T2368 3658-3660 CD denotes 17
T2369 3660-3661 NNP denotes ]
T2370 3661-3662 . denotes .
T2371 3663-3668 CD denotes Three
T2372 3669-3674 JJ denotes other
T2373 3675-3689 NNS denotes investigations
T2374 3690-3694 VBP denotes have
T2375 3695-3703 VBN denotes reported
T2376 3704-3708 IN denotes that
T2377 3709-3714 JJ denotes human
T2378 3715-3725 NNS denotes leukocytes
T2379 3726-3729 CC denotes and
T2380 3730-3735 JJ denotes human
T2381 3736-3744 JJ denotes vascular
T2382 3745-3756 JJ denotes endothelial
T2383 3757-3762 NNS denotes cells
T2384 3763-3770 VBP denotes produce
T2385 3771-3775 NN denotes IL-8
T2386 3776-3778 IN denotes in
T2387 3779-3787 NN denotes response
T2388 3788-3790 TO denotes to
T2389 3791-3798 VB denotes zymosan
T2390 3799-3800 NNP denotes [
T2391 3800-3802 CD denotes 18
T2392 3802-3803 NNP denotes ]
T2393 3804-3806 CC denotes or
T2394 3807-3808 DT denotes a
T2395 3809-3822 JJ denotes water-soluble
T2396 3823-3826 JJ denotes β-1
T2397 3826-3827 NN denotes →
T2398 3827-3837 JJ denotes 3-D-glucan
T2399 3838-3839 NNP denotes [
T2400 3839-3843 CD denotes 6,19
T2401 3843-3844 NNP denotes ]
T2402 3844-3845 . denotes .
T2403 3846-3848 IN denotes In
T2404 3849-3857 NN denotes addition
T2405 3857-3858 , denotes ,
T2406 3859-3862 JJ denotes β-1
T2407 3862-3863 NN denotes →
T2408 3863-3874 NNS denotes 3-D-glucans
T2409 3875-3879 VBP denotes seem
T2410 3880-3882 TO denotes to
T2411 3883-3885 VB denotes be
T2412 3886-3890 JJ denotes able
T2413 3891-3893 TO denotes to
T2414 3894-3900 VB denotes modify
T2415 3901-3904 DT denotes the
T2416 3905-3913 NN denotes response
T2417 3914-3916 TO denotes to
T2418 3917-3933 JJ denotes pro-inflammatory
T2419 3934-3941 NNS denotes stimuli
T2420 3942-3944 CC denotes or
T2421 3945-3949 RB denotes even
T2422 3950-3956 NNS denotes sepsis
T2423 3956-3957 . denotes .
T2424 3958-3960 IN denotes In
T2425 3961-3962 DT denotes a
T2426 3963-3969 JJ denotes murine
T2427 3970-3983 JJ denotes polymicrobial
T2428 3984-3990 NN denotes sepsis
T2429 3991-3996 NN denotes model
T2430 3996-3997 , denotes ,
T2431 3998-4001 JJ denotes β-1
T2432 4001-4002 NN denotes →
T2433 4002-4012 JJ denotes 3-D-glucan
T2434 4013-4014 NNP denotes [
T2435 4014-4016 CD denotes 20
T2436 4016-4017 NNP denotes ]
T2437 4018-4027 NN denotes treatment
T2438 4028-4036 VBD denotes resulted
T2439 4037-4039 IN denotes in
T2440 4040-4049 VBN denotes decreased
T2441 4050-4056 JJ denotes septic
T2442 4057-4066 NN denotes morbidity
T2443 4067-4070 CC denotes and
T2444 4071-4080 NN denotes mortality
T2445 4081-4089 VBD denotes mediated
T2446 4090-4093 IN denotes via
T2447 4094-4104 NN denotes inhibition
T2448 4105-4107 IN denotes of
T2449 4108-4112 NNP denotes NFκB
T2450 4113-4116 CC denotes and
T2451 4117-4128 NN denotes stimulation
T2452 4129-4131 IN denotes of
T2453 4132-4135 DT denotes the
T2454 4136-4161 JJ denotes phosphoinositide-3-kinase
T2455 4162-4163 -LRB- denotes (
T2456 4163-4167 NNP denotes PI3K
T2457 4167-4168 -RRB- denotes )
T2458 4169-4176 NN denotes pathway
T2459 4177-4178 NNP denotes [
T2460 4178-4183 CD denotes 21,22
T2461 4183-4184 NNP denotes ]
T2462 4184-4185 . denotes .
T2463 4186-4191 DT denotes These
T2464 4192-4195 CC denotes and
T2465 4196-4201 JJ denotes other
T2466 4202-4208 NN denotes animal
T2467 4209-4216 NNS denotes studies
T2468 4217-4218 NNP denotes [
T2469 4218-4223 CD denotes 23,24
T2470 4223-4224 NNP denotes ]
T2471 4225-4227 RB denotes as
T2472 4228-4232 RB denotes well
T2473 4233-4235 IN denotes as
T2474 4236-4237 DT denotes a
T2475 4238-4246 JJ denotes clinical
T2476 4247-4252 NN denotes trial
T2477 4253-4254 NNP denotes [
T2478 4254-4256 CD denotes 25
T2479 4256-4257 JJ denotes ]
T2480 4258-4265 NN denotes support
T2481 4266-4267 DT denotes a
T2482 4268-4278 JJ denotes protective
T2483 4279-4283 NN denotes role
T2484 4284-4286 IN denotes of
T2485 4287-4290 JJ denotes β-1
T2486 4290-4291 NN denotes →
T2487 4291-4301 NN denotes 3-D-glucan
T2488 4302-4304 IN denotes in
T2489 4305-4312 JJ denotes certain
T2490 4313-4329 JJ denotes pro-inflammatory
T2491 4330-4340 NNS denotes conditions
T2492 4340-4341 . denotes .
T2493 4342-4345 DT denotes The
T2494 4346-4356 NNS denotes mechanisms
T2495 4357-4367 VBG denotes underlying
T2496 4368-4373 DT denotes these
T2497 4374-4384 JJ denotes beneficial
T2498 4385-4392 NNS denotes effects
T2499 4393-4395 IN denotes of
T2500 4396-4399 JJ denotes β-1
T2501 4399-4400 NN denotes →
T2502 4400-4410 NN denotes 3-D-glucan
T2503 4411-4414 VBP denotes are
T2504 4415-4419 RB denotes only
T2505 4420-4429 RB denotes partially
T2506 4430-4438 VBN denotes resolved
T2507 4438-4439 , denotes ,
T2508 4440-4450 RB denotes especially
T2509 4451-4453 IN denotes in
T2510 4454-4460 NNS denotes humans
T2511 4460-4461 . denotes .
T2512 4462-4466 RB denotes Thus
T2513 4466-4467 , denotes ,
T2514 4468-4471 DT denotes the
T2515 4472-4475 NN denotes aim
T2516 4476-4478 IN denotes of
T2517 4479-4483 DT denotes this
T2518 4484-4489 NN denotes study
T2519 4490-4493 VBD denotes was
T2520 4494-4496 TO denotes to
T2521 4497-4506 VB denotes elucidate
T2522 4507-4516 JJ denotes molecular
T2523 4517-4520 CC denotes and
T2524 4521-4529 JJ denotes cellular
T2525 4530-4540 NNS denotes mechanisms
T2526 4541-4543 IN denotes of
T2527 4544-4547 JJ denotes β-1
T2528 4547-4548 NN denotes →
T2529 4548-4559 NNS denotes 3-D-glucans
T2530 4560-4562 IN denotes on
T2531 4563-4568 JJ denotes human
T2532 4569-4579 NNS denotes leukocytes
T2533 4580-4582 IN denotes in
T2534 4583-4599 JJ denotes pro-inflammatory
T2535 4600-4610 NNS denotes conditions
T2536 4611-4615 IN denotes with
T2537 4616-4623 JJ denotes special
T2538 4624-4632 NN denotes emphasis
T2539 4633-4635 IN denotes on
T2540 4636-4639 DT denotes the
T2541 4640-4648 NN denotes cytokine
T2542 4649-4656 NN denotes profile
T2543 4657-4660 CC denotes and
T2544 4661-4664 PRP$ denotes its
T2545 4665-4680 JJ denotes transcriptional
T2546 4681-4691 NN denotes regulation
T2547 4691-4692 . denotes .
T2548 4693-4696 IN denotes For
T2549 4697-4701 DT denotes this
T2550 4702-4709 NN denotes purpose
T2551 4709-4710 , denotes ,
T2552 4711-4721 JJ denotes peripheral
T2553 4722-4727 NN denotes blood
T2554 4728-4739 NN denotes mononuclear
T2555 4740-4745 NNS denotes cells
T2556 4746-4747 -LRB- denotes (
T2557 4747-4751 NNP denotes PBMC
T2558 4751-4752 -RRB- denotes )
T2559 4753-4757 VBD denotes were
T2560 4758-4765 VBN denotes exposed
T2561 4766-4768 TO denotes to
T2562 4769-4770 DT denotes a
T2563 4771-4783 JJ denotes well-defined
T2564 4784-4787 JJ denotes β-1
T2565 4787-4788 NN denotes →
T2566 4788-4798 NN denotes 3-D-glucan
T2567 4798-4799 , denotes ,
T2568 4800-4804 FW denotes i.e.
T2569 4805-4811 FW denotes glucan
T2570 4812-4821 FW denotes phosphate
T2571 4822-4823 -LRB- denotes (
T2572 4823-4825 NNP denotes GP
T2573 4825-4826 -RRB- denotes )
T2574 4827-4828 NNP denotes [
T2575 4828-4833 CD denotes 20,26
T2576 4833-4834 NNP denotes ]
T2577 4834-4835 , denotes ,
T2578 4836-4841 RB denotes alone
T2579 4842-4844 CC denotes or
T2580 4845-4859 RB denotes simultaneously
T2581 4860-4864 IN denotes with
T2582 4865-4868 NNP denotes LPS
T2583 4869-4873 IN denotes from
T2584 4874-4887 JJ denotes gram-negative
T2585 4888-4896 NNS denotes bacteria
T2586 4897-4899 CC denotes or
T2587 4900-4903 DT denotes the
T2588 4904-4916 NN denotes superantigen
T2589 4917-4923 NN denotes TSST-1
T2590 4924-4928 IN denotes from
T2591 4929-4942 JJ denotes gram-positive
T2592 4943-4951 NNS denotes bacteria
T2593 4952-4956 IN denotes over
T2594 4957-4959 CD denotes 48
T2595 4960-4962 NN denotes h.
T2596 4963-4970 IN denotes Because
T2597 4971-4973 IN denotes of
T2598 4974-4977 DT denotes the
T2599 4978-4987 JJ denotes potential
T2600 4988-4994 NN denotes effect
T2601 4995-4997 IN denotes of
T2602 4998-5001 JJ denotes β-1
T2603 5001-5002 NN denotes →
T2604 5002-5012 NN denotes 3-D-glucan
T2605 5013-5015 IN denotes on
T2606 5016-5024 NN denotes cytokine
T2607 5025-5035 NN denotes production
T2608 5036-5037 NNP denotes [
T2609 5037-5045 CD denotes 12,16-19
T2610 5045-5046 NNP denotes ]
T2611 5046-5047 , denotes ,
T2612 5048-5052 NNP denotes TNFα
T2613 5052-5053 , denotes ,
T2614 5054-5059 NNP denotes IL-1β
T2615 5059-5060 , denotes ,
T2616 5061-5065 NNP denotes IL-6
T2617 5065-5066 , denotes ,
T2618 5067-5071 NNP denotes IL-8
T2619 5072-5075 CC denotes and
T2620 5076-5082 NNP denotes IL-1RA
T2621 5083-5087 VBD denotes were
T2622 5088-5096 VBN denotes measured
T2623 5097-5099 RB denotes as
T2624 5100-5104 RB denotes well
T2625 5105-5107 IN denotes as
T2626 5108-5112 NNP denotes IFNγ
T2627 5112-5113 , denotes ,
T2628 5114-5118 NNP denotes IL-2
T2629 5118-5119 , denotes ,
T2630 5120-5124 NN denotes IL-4
T2631 5124-5125 , denotes ,
T2632 5126-5131 NNP denotes IL-10
T2633 5131-5132 , denotes ,
T2634 5133-5138 NNP denotes IL-12
T2635 5139-5142 CC denotes and
T2636 5143-5148 NNP denotes TGFβ1
T2637 5148-5149 . denotes .
T2638 5150-5165 RB denotes Correspondingly
T2639 5165-5166 , denotes ,
T2640 5167-5171 CD denotes four
T2641 5172-5176 NNP denotes NFκB
T2642 5177-5182 NNS denotes sites
T2643 5183-5187 IN denotes from
T2644 5188-5191 DT denotes the
T2645 5192-5196 NNP denotes TNFα
T2646 5197-5205 NN denotes promoter
T2647 5206-5207 -LRB- denotes (
T2648 5207-5208 FW denotes κ
T2649 5209-5218 NN denotes consensus
T2650 5218-5219 , denotes ,
T2651 5220-5222 CD denotes κ1
T2652 5222-5223 , denotes ,
T2653 5224-5226 CD denotes κ2
T2654 5226-5227 , denotes ,
T2655 5228-5230 CD denotes κ3
T2656 5230-5231 -RRB- denotes )
T2657 5232-5233 NNP denotes [
T2658 5233-5235 CD denotes 27
T2659 5235-5236 NNP denotes ]
T2660 5236-5237 , denotes ,
T2661 5238-5239 DT denotes a
T2662 5240-5241 NN denotes κ
T2663 5242-5251 NN denotes consensus
T2664 5252-5256 NN denotes site
T2665 5257-5261 IN denotes from
T2666 5262-5265 DT denotes the
T2667 5266-5270 NN denotes IL-8
T2668 5271-5279 NN denotes promoter
T2669 5280-5281 NNP denotes [
T2670 5281-5283 CD denotes 28
T2671 5283-5284 NNP denotes ]
T2672 5284-5285 , denotes ,
T2673 5286-5288 DT denotes an
T2674 5289-5293 NNP denotes NFAT
T2675 5294-5298 NN denotes site
T2676 5299-5303 IN denotes from
T2677 5304-5307 DT denotes the
T2678 5308-5312 NNP denotes IFNγ
T2679 5313-5321 NN denotes promoter
T2680 5322-5323 -LRB- denotes (
T2681 5323-5327 NNP denotes ATP2
T2682 5327-5328 -RRB- denotes )
T2683 5329-5330 NNP denotes [
T2684 5330-5332 CD denotes 29
T2685 5332-5333 NNP denotes ]
T2686 5334-5337 CC denotes and
T2687 5338-5339 DT denotes a
T2688 5340-5349 NN denotes consensus
T2689 5350-5356 NNP denotes NFIL-6
T2690 5357-5361 NN denotes site
T2701 5405-5412 IN denotes Because
T2702 5413-5415 IN denotes of
T2703 5416-5419 DT denotes the
T2704 5420-5437 JJ denotes anti-inflammatory
T2705 5438-5442 NN denotes role
T2706 5443-5445 IN denotes of
T2707 5446-5452 NNP denotes IL-1RA
T2708 5452-5453 , denotes ,
T2709 5454-5456 PRP denotes we
T2710 5457-5464 VBD denotes focused
T2711 5465-5467 IN denotes on
T2712 5468-5475 JJ denotes binding
T2713 5476-5478 IN denotes of
T2714 5479-5492 NN denotes transcription
T2715 5493-5500 NNS denotes factors
T2716 5501-5503 TO denotes to
T2717 5504-5507 DT denotes the
T2718 5508-5514 NN denotes IL-1RA
T2719 5515-5523 NN denotes promoter
T2720 5523-5524 . denotes .
T2721 5525-5527 DT denotes An
T2722 5528-5538 JJ denotes inhibitory
T2723 5539-5546 NN denotes element
T2724 5547-5550 CC denotes and
T2725 5551-5556 CD denotes three
T2726 5557-5572 JJ denotes positive-acting
T2727 5573-5585 JJ denotes LPS-response
T2728 5586-5594 NNS denotes elements
T2729 5595-5596 -LRB- denotes (
T2730 5596-5601 NNP denotes LRE-1
T2731 5601-5602 , denotes ,
T2732 5603-5608 NNP denotes LRE-2
T2733 5609-5612 CC denotes and
T2734 5613-5618 NNP denotes LRE-3
T2735 5618-5619 -RRB- denotes )
T2736 5620-5622 IN denotes in
T2737 5623-5626 DT denotes the
T2738 5627-5633 NN denotes IL-1RA
T2739 5634-5642 NN denotes promoter
T2740 5642-5643 , denotes ,
T2741 5644-5653 VBG denotes including
T2742 5654-5658 NNP denotes NFκB
T2743 5658-5659 , denotes ,
T2744 5660-5662 NNP denotes PU
T2745 5662-5664 CD denotes .1
T2746 5665-5668 CC denotes and
T2747 5669-5675 NNP denotes NFIL-6
T2748 5676-5681 NNS denotes sites
T2749 5681-5682 , denotes ,
T2750 5683-5687 VBP denotes have
T2751 5688-5692 VBN denotes been
T2752 5693-5706 VBN denotes characterized
T2753 5707-5717 RB denotes previously
T2754 5718-5719 NNP denotes [
T2755 5719-5724 CD denotes 30-33
T2756 5724-5725 NNP denotes ]
T2757 5725-5726 . denotes .
T2758 5727-5732 VBG denotes Using
T2759 5733-5746 JJ denotes computational
T2760 5747-5755 NN denotes analysis
T2761 5756-5759 IN denotes for
T2762 5760-5768 NN denotes homology
T2763 5769-5775 NN denotes search
T2764 5776-5777 NNP denotes [
T2765 5777-5779 CD denotes 34
T2766 5779-5780 NNP denotes ]
T2767 5780-5781 , denotes ,
T2768 5782-5784 PRP denotes we
T2769 5785-5791 VBD denotes looked
T2770 5792-5795 IN denotes for
T2771 5796-5799 JJ denotes new
T2772 5800-5807 JJ denotes binding
T2773 5808-5814 NNS denotes motifs
T2774 5815-5817 IN denotes in
T2775 5818-5821 DT denotes the
T2776 5822-5828 NN denotes IL-1RA
T2777 5829-5837 NN denotes promoter
T2778 5837-5838 . denotes .
T3832 5849-5856 VBG denotes Binding
T3833 5857-5867 NNS denotes activities
T3834 5868-5870 IN denotes of
T3835 5871-5875 NNP denotes NFκB
T3836 5875-5876 , denotes ,
T3837 5877-5883 NNP denotes NFIL-6
T3838 5884-5887 CC denotes and
T3839 5888-5892 NNP denotes NFAT
T3840 5893-5897 IN denotes from
T3841 5898-5903 JJ denotes human
T3842 5904-5908 NNP denotes PBMC
T3843 5909-5911 TO denotes to
T3844 5912-5915 DT denotes the
T3845 5916-5920 NNP denotes TNFα
T3846 5920-5921 , denotes ,
T3847 5922-5926 NNP denotes IL-6
T3848 5927-5930 CC denotes and
T3849 5931-5935 NNP denotes IFNγ
T3850 5936-5945 NNS denotes promoters
T3851 5946-5955 VBG denotes following
T3852 5956-5958 DT denotes an
T3853 5959-5961 IN denotes in
T3854 5962-5967 NN denotes vitro
T3855 5968-5979 NN denotes stimulation
T3856 5980-5981 -LRB- denotes (
T3857 5981-5982 CD denotes 1
T3858 5983-5984 NN denotes h
T3859 5984-5985 -RRB- denotes )
T3860 5986-5990 IN denotes with
T3861 5991-5994 NNP denotes LPS
T3862 5994-5995 , denotes ,
T3863 5996-6002 NNP denotes TSST-1
T3864 6002-6003 , denotes ,
T3865 6004-6006 NNP denotes GP
T3866 6006-6007 , denotes ,
T3867 6008-6010 NNP denotes GP
T3868 6011-6012 NNP denotes +
T3869 6013-6016 NNP denotes LPS
T3870 6017-6020 CC denotes and
T3871 6021-6023 NNP denotes GP
T3872 6024-6025 NNP denotes +
T3873 6026-6032 NNP denotes TSST-1
T3874 6033-6035 NNP denotes GP
T3875 6036-6043 VBD denotes induced
T3876 6044-6048 NN denotes band
T3877 6049-6055 NNS denotes shifts
T3878 6055-6056 , denotes ,
T3879 6057-6067 VBG denotes indicating
T3880 6068-6075 JJ denotes binding
T3881 6076-6078 IN denotes of
T3882 6079-6083 NNP denotes NFκB
T3883 6084-6086 RB denotes as
T3884 6087-6091 RB denotes well
T3885 6092-6094 IN denotes as
T3886 6095-6097 IN denotes of
T3887 6098-6104 NN denotes NFIL-6
T3888 6105-6107 TO denotes to
T3889 6108-6111 DT denotes the
T3890 6112-6125 JJ denotes corresponding
T3891 6126-6129 NNP denotes DNA
T3892 6130-6146 NNS denotes oligonucleotides
T3893 6147-6148 -LRB- denotes (
T3894 6148-6149 FW denotes κ
T3895 6150-6159 NN denotes consensus
T3896 6159-6160 , denotes ,
T3897 6161-6163 CD denotes κ1
T3898 6163-6164 , denotes ,
T3899 6165-6167 CD denotes κ2
T3900 6167-6168 , denotes ,
T3901 6169-6171 CD denotes κ3
T3902 6172-6177 NNS denotes sites
T3903 6178-6182 IN denotes from
T3904 6183-6186 DT denotes the
T3905 6187-6191 NNP denotes TNFα
T3906 6192-6200 NN denotes promoter
T3907 6200-6201 : denotes ;
T3908 6202-6203 VB denotes κ
T3909 6204-6213 NN denotes consensus
T3910 6214-6218 IN denotes from
T3911 6219-6222 DT denotes the
T3912 6223-6227 NN denotes IL-8
T3913 6228-6236 NN denotes promoter
T3914 6236-6237 : denotes ;
T3915 6238-6253 NN denotes NFIL-6consensus
T3916 6254-6258 IN denotes from
T3917 6259-6262 DT denotes the
T3918 6263-6267 NNP denotes IL-6
T3919 6268-6276 NN denotes promoter
T3920 6276-6277 : denotes ;
T3921 6278-6283 NNP denotes Table
T3922 6284-6285 CD denotes 1
T3923 6285-6286 : denotes ;
T3924 6287-6291 NNP denotes Fig.
T3925 6292-6294 NNP denotes 1A
T3926 6294-6295 -RRB- denotes )
T3927 6295-6296 . denotes .
T3928 6297-6300 DT denotes The
T3929 6301-6307 NN denotes extent
T3930 6308-6310 IN denotes of
T3931 6311-6314 DT denotes the
T3932 6315-6319 NN denotes band
T3933 6320-6326 NNS denotes shifts
T3934 6327-6334 VBN denotes induced
T3935 6335-6337 IN denotes by
T3936 6338-6340 NNP denotes GP
T3937 6341-6344 VBD denotes was
T3938 6345-6348 RB denotes not
T3939 6349-6362 RB denotes statistically
T3940 6363-6372 JJ denotes different
T3941 6373-6377 WRB denotes when
T3942 6378-6386 VBN denotes compared
T3943 6387-6389 TO denotes to
T3944 6390-6393 NNP denotes LPS
T3945 6394-6396 CC denotes or
T3946 6397-6403 NNP denotes TSST-1
T3947 6404-6405 -LRB- denotes (
T3948 6405-6409 NNP denotes Fig.
T3949 6410-6412 NNP denotes 1B
T3950 6412-6413 -RRB- denotes )
T3951 6413-6414 . denotes .
T3952 6415-6416 DT denotes A
T3953 6417-6427 NN denotes supershift
T3954 6427-6428 , denotes ,
T3955 6429-6438 VBN denotes conducted
T3956 6439-6442 IN denotes for
T3957 6443-6445 DT denotes an
T3958 6446-6450 NNP denotes NFκB
T3959 6451-6460 NN denotes consensus
T3960 6461-6465 NN denotes site
T3961 6466-6470 IN denotes from
T3962 6471-6474 DT denotes the
T3963 6475-6479 NN denotes IL-8
T3964 6480-6488 NN denotes promoter
T3965 6488-6489 , denotes ,
T3966 6490-6502 VBD denotes demonstrated
T3967 6503-6504 DT denotes a
T3968 6505-6515 JJ denotes GP-induced
T3969 6516-6527 NN denotes predominant
T3970 6528-6535 JJ denotes binding
T3971 6536-6538 IN denotes of
T3972 6539-6543 NNP denotes NFκB
T3973 6544-6547 CD denotes p65
T3974 6548-6551 CC denotes and
T3975 6552-6554 TO denotes to
T3976 6555-6556 DT denotes a
T3977 6557-6563 JJR denotes lesser
T3978 6564-6570 NN denotes degree
T3979 6571-6573 IN denotes of
T3980 6574-6577 CD denotes p50
T3981 6578-6579 -LRB- denotes (
T3982 6579-6583 NNP denotes Fig.
T3983 6584-6586 NNP denotes 1A
T3984 6586-6587 -RRB- denotes )
T3985 6587-6588 . denotes .
T3986 6589-6600 RB denotes Accordingly
T3987 6600-6601 , denotes ,
T3988 6602-6604 DT denotes an
T3989 6605-6615 NN denotes immunoblot
T3990 6616-6618 IN denotes of
T3991 6619-6626 JJ denotes nuclear
T3992 6627-6635 NNS denotes extracts
T3993 6636-6640 IN denotes from
T3994 6641-6651 JJ denotes GP-treated
T3995 6652-6656 NNP denotes PBMC
T3996 6657-6663 VBD denotes showed
T3997 6664-6665 DT denotes a
T3998 6666-6672 JJ denotes strong
T3999 6673-6680 JJ denotes binding
T4000 6681-6683 IN denotes of
T4001 6684-6688 NNP denotes NFκB
T4002 6689-6692 CD denotes p65
T4003 6693-6696 CC denotes and
T4004 6697-6698 DT denotes a
T4005 6699-6705 JJR denotes weaker
T4006 6706-6714 NN denotes reaction
T4007 6715-6717 IN denotes of
T4008 6718-6721 CD denotes p50
T4009 6721-6722 , denotes ,
T4010 6723-6730 IN denotes whereas
T4011 6731-6734 CD denotes p52
T4012 6735-6738 VBD denotes was
T4013 6739-6747 JJ denotes negative
T4014 6748-6749 -LRB- denotes (
T4015 6749-6753 JJ denotes Fig.
T4016 6754-6755 CD denotes 2
T4017 6755-6756 -RRB- denotes )
T4018 6756-6757 . denotes .
T4019 6758-6770 JJ denotes Simultaneous
T4020 6771-6783 NN denotes co-treatment
T4021 6784-6786 IN denotes of
T4022 6787-6791 NNP denotes PBMC
T4023 6792-6796 IN denotes with
T4024 6797-6799 NNP denotes GP
T4025 6800-6803 VBD denotes did
T4026 6804-6807 RB denotes not
T4027 6808-6814 VB denotes change
T4028 6815-6818 DT denotes the
T4029 6819-6830 JJ denotes LPS-induced
T4030 6831-6835 NN denotes NFκB
T4031 6836-6843 JJ denotes binding
T4032 6844-6846 TO denotes to
T4033 6847-6853 NNS denotes oligos
T4034 6854-6858 IN denotes from
T4035 6859-6862 DT denotes the
T4036 6863-6867 NNP denotes TNFα
T4037 6868-6876 NN denotes promoter
T4038 6877-6890 RB denotes significantly
T4039 6891-6892 -LRB- denotes (
T4040 6892-6896 NNP denotes Fig.
T4041 6897-6899 NNP denotes 1B
T4042 6899-6900 -RRB- denotes )
T4043 6900-6901 , denotes ,
T4044 6902-6905 CC denotes but
T4045 6906-6919 RB denotes substantially
T4046 6920-6929 VBD denotes decreased
T4047 6930-6933 DT denotes the
T4048 6934-6948 JJ denotes TSST-1-induced
T4049 6949-6953 NN denotes NFκB
T4050 6954-6961 JJ denotes binding
T4051 6962-6966 WRB denotes when
T4052 6967-6975 VBN denotes compared
T4053 6976-6978 TO denotes to
T4054 6979-6985 CD denotes TSST-1
T4055 6986-6988 CC denotes or
T4056 6989-6991 NNP denotes GP
T4057 6992-6993 -LRB- denotes (
T4058 6993-6996 CD denotes 100
T4059 6997-6999 NN denotes μg
T4060 6999-7000 -RRB- denotes )
T4061 7001-7004 CC denotes and
T4062 7005-7009 RB denotes thus
T4063 7010-7018 VBD denotes differed
T4064 7019-7029 RB denotes completely
T4065 7030-7034 IN denotes from
T4066 7035-7038 DT denotes the
T4067 7039-7050 JJ denotes theoretical
T4068 7051-7056 NN denotes value
T4069 7057-7059 IN denotes of
T4070 7060-7067 NNP denotes GP/TSST
T4071 7067-7069 CD denotes -1
T4072 7070-7074 NN denotes calc
T4073 7074-7075 . denotes .
T4074 7076-7077 -LRB- denotes (
T4075 7077-7078 FW denotes n
T4076 7079-7080 SYM denotes =
T4077 7081-7082 CD denotes 4
T4078 7082-7083 : denotes ;
T4079 7084-7085 VB denotes p
T4080 7086-7087 RB denotes <
T4081 7088-7092 CD denotes 0.05
T4082 7093-7096 FW denotes vs.
T4083 7097-7104 NNP denotes GP/TSST
T4084 7104-7106 CD denotes -1
T4085 7107-7111 NN denotes calc
T4086 7111-7112 . denotes .
T4087 7113-7116 CC denotes and
T4088 7117-7118 VB denotes p
T4089 7119-7120 SYM denotes =
T4090 7121-7125 CD denotes 0.07
T4091 7126-7129 FW denotes vs.
T4092 7130-7136 CD denotes TSST-1
T4093 7136-7137 : denotes ;
T4094 7138-7142 NNP denotes Fig.
T4095 7143-7145 NNP denotes 1B
T4096 7145-7146 -RRB- denotes )
T4097 7146-7147 . denotes .
T4098 7148-7150 NNP denotes GP
T4099 7151-7154 VBD denotes was
T4100 7155-7159 RB denotes also
T4101 7160-7164 JJ denotes able
T4102 7165-7167 TO denotes to
T4103 7168-7174 VB denotes induce
T4104 7175-7179 NN denotes band
T4105 7180-7186 NNS denotes shifts
T4106 7187-7197 JJ denotes indicative
T4107 7198-7200 IN denotes of
T4108 7201-7208 JJ denotes binding
T4109 7209-7211 IN denotes of
T4110 7212-7222 JJ denotes particular
T4111 7223-7231 NNS denotes variants
T4112 7232-7234 IN denotes of
T4113 7235-7239 NNP denotes NFAT
T4114 7240-7242 TO denotes to
T4115 7243-7245 DT denotes an
T4116 7246-7251 NN denotes oligo
T4117 7252-7256 IN denotes from
T4118 7257-7260 DT denotes the
T4119 7261-7265 NNP denotes IFNγ
T4120 7266-7274 NN denotes promoter
T4121 7275-7276 -LRB- denotes (
T4122 7276-7280 NNP denotes Fig.
T4123 7281-7283 NNP denotes 1A
T4124 7283-7284 -RRB- denotes )
T4125 7284-7285 . denotes .
T4126 7286-7288 DT denotes An
T4127 7289-7299 NN denotes immunoblot
T4128 7300-7303 IN denotes for
T4129 7304-7307 CD denotes two
T4130 7308-7312 NNP denotes NFAT
T4131 7313-7321 NNS denotes subunits
T4132 7322-7334 VBD denotes demonstrated
T4133 7335-7336 DT denotes a
T4134 7337-7347 JJ denotes GP-induced
T4135 7348-7355 JJ denotes binding
T4136 7356-7358 IN denotes of
T4137 7359-7365 NNP denotes NFATc2
T4138 7366-7369 CC denotes and
T4139 7370-7372 TO denotes to
T4140 7373-7374 DT denotes a
T4141 7375-7381 JJR denotes lesser
T4142 7382-7388 NN denotes degree
T4143 7389-7391 IN denotes of
T4144 7392-7398 NNP denotes NFATc1
T4145 7399-7400 -LRB- denotes (
T4146 7400-7404 NNP denotes Fig.
T4147 7405-7406 CD denotes 2
T4148 7406-7407 -RRB- denotes )
T4149 7407-7408 . denotes .
T18209 34744-34745 . denotes .
T22753 10779-10780 . denotes .
T26282 28064-28065 . denotes .
T26281 28056-28064 VBN denotes depicted
T26280 28052-28055 VBP denotes are
T26279 28046-28051 NNS denotes sites
T26278 28038-28045 JJ denotes binding
T26277 28031-28037 NN denotes factor
T26276 28017-28030 NN denotes transcription
T26275 28006-28016 JJ denotes regulatory
T26274 28004-28005 -RRB- denotes )
T26273 28000-28004 JJ denotes gray
T26272 27999-28000 -LRB- denotes (
T26271 27988-27998 RB denotes negatively
T26270 27984-27987 CC denotes and
T26269 27982-27983 -RRB- denotes )
T26268 27977-27982 JJ denotes black
T26267 27976-27977 -LRB- denotes (
T26266 27965-27975 RB denotes positively
T26265 27963-27964 , denotes ,
T26264 27962-27963 -RRB- denotes )
T26263 27957-27962 VBN denotes boxed
T26262 27956-27957 -LRB- denotes (
T26261 27946-27955 VBN denotes described
T26260 27940-27945 RB denotes newly
T26259 27936-27939 CC denotes and
T26258 27934-27935 NNP denotes ]
T26257 27929-27934 CD denotes 30-33
T26256 27928-27929 NNP denotes [
T26255 27926-27927 -RRB- denotes )
T26254 27921-27926 NNP denotes LRE-1
T26253 27920-27921 -LRB- denotes (
T26252 27909-27919 RB denotes previously
T26251 27906-27908 IN denotes of
T26250 27896-27905 NNS denotes locations
T26249 27887-27895 JJ denotes Relative
T17543 33032-33033 -LRB- denotes (
T17542 33021-33031 NN denotes 3-D-glucan
T17541 33020-33021 NN denotes →
T17540 33017-33020 JJ denotes β-1
T17539 33002-33016 VBN denotes phosphorylated
T17538 32994-33001 JJ denotes soluble
T17537 32988-32993 NNP denotes Water
T17536 32978-32987 NNPS denotes Materials
T17575 33194-33195 , denotes ,
T17574 33189-33194 NNS denotes media
T17573 33181-33188 JJ denotes aqueous
T17572 33178-33180 IN denotes in
T17571 33168-33177 VBN denotes dissolved
T17570 33164-33167 VBD denotes was
T17569 33161-33163 NNP denotes GP
T17568 33159-33160 . denotes .
T17567 33158-33159 NNP denotes ]
T17566 33153-33158 CD denotes 20,26
T17565 33152-33153 NNP denotes [
T17564 33141-33151 RB denotes previously
T17563 33132-33140 VBN denotes reported
T17562 33129-33131 IN denotes as
T17561 33118-33128 VBN denotes determined
T17560 33113-33117 VBD denotes were
T17559 33110-33112 NNP denotes GP
T17558 33107-33109 IN denotes of
T17557 33091-33106 NNS denotes characteristics
T17556 33075-33090 JJ denotes physicochemical
T17555 33071-33074 DT denotes The
T17554 33069-33070 . denotes .
T17553 33068-33069 NNP denotes ]
T17552 33066-33068 CD denotes 20
T17551 33065-33066 NNP denotes [
T17550 33058-33064 IN denotes before
T17549 33053-33057 VBN denotes done
T17548 33050-33052 IN denotes as
T17547 33041-33049 VBN denotes prepared
T17546 33037-33040 VBD denotes was
T17545 33035-33036 -RRB- denotes )
T17544 33033-33035 NNP denotes GP
T17328 32399-32407 VBD denotes switched
T17327 32397-32398 , denotes ,
T17326 32389-32397 RB denotes moreover
T26171 7418-7423 NN denotes Sense
T26172 7424-7430 NN denotes strand
T26173 7431-7433 IN denotes of
T26174 7434-7450 NNS denotes oligonucleotides
T26175 7451-7455 VBN denotes used
T26176 7456-7458 IN denotes in
T26177 7459-7464 NNS denotes EMSAs
T26178 7464-7465 . denotes .
T17791 33519-33522 DT denotes the
T17790 33514-33518 IN denotes with
T17789 33510-33513 CC denotes and
T17788 33498-33509 NN denotes declaration
T17787 33489-33497 NNP denotes Helsinki
T17786 33485-33488 DT denotes the
T17785 33480-33484 IN denotes with
T17784 33469-33479 NN denotes compliance
T17783 33466-33468 IN denotes in
T17782 33459-33465 NNS denotes donors
T17781 33453-33458 NN denotes blood
T17780 33445-33452 JJ denotes healthy
T17779 33440-33444 IN denotes from
T17778 33431-33439 VBN denotes obtained
T17777 33426-33430 VBD denotes were
T17776 33420-33425 NNS denotes coats
T17775 33414-33419 NNP denotes Buffy
T17774 33409-33413 NNP denotes PBMC
T17773 33403-33408 JJ denotes human
T17772 33400-33402 IN denotes of
T17771 33390-33399 NN denotes Isolation
T17325 32387-32388 , denotes ,
T17335 32457-32472 JJ denotes IL-1RA-mediated
T17334 32454-32456 DT denotes an
T17333 32451-32453 TO denotes to
T17332 32442-32450 NN denotes response
T17331 32427-32441 JJ denotes TSST-1-induced
T17330 32410-32426 JJ denotes pro-inflammatory
T17329 32408-32409 DT denotes a
T17324 32384-32387 CC denotes and
T17323 32377-32383 CD denotes TSST-1
T17322 32372-32376 IN denotes from
T17321 32367-32371 RB denotes also
T17320 32363-32366 CC denotes and
T17319 32359-32362 NNP denotes LPS
T17318 32354-32358 IN denotes from
T17317 32344-32353 JJ denotes different
T17316 32336-32343 NN denotes profile
T17315 32327-32335 NN denotes cytokine
T17314 32316-32326 JJ denotes subsequent
T17313 32314-32315 DT denotes a
T17312 32310-32313 CC denotes and
T17311 32302-32309 JJ denotes binding
T17310 32295-32301 NN denotes factor
T17309 32281-32294 NN denotes transcription
T17308 32279-32280 DT denotes a
T17307 32271-32278 VBD denotes induced
T17306 32261-32270 NN denotes phosphate
T17305 32254-32260 NN denotes glucan
T17304 32248-32253 NN denotes vitro
T17303 32245-32247 IN denotes in
T17302 32240-32244 IN denotes that
T17301 32227-32239 VBD denotes demonstrated
T17300 32222-32226 NNS denotes data
T17299 32218-32221 PRP$ denotes our
T17298 32216-32217 , denotes ,
T17396 32826-32828 IN denotes of
T17395 32818-32825 NN denotes concept
T17394 32814-32817 DT denotes the
T17393 32806-32813 VB denotes support
T17392 32800-32805 MD denotes might
T17391 32791-32799 NNS denotes findings
T17390 32787-32790 PRP$ denotes our
T17389 32785-32786 , denotes ,
T17388 32784-32785 NNP denotes ]
T17387 32779-32784 CD denotes 22,37
T17386 32778-32779 NNP denotes [
T17385 32770-32777 NNS denotes studies
T17384 32765-32769 NN denotes vivo
T17383 32762-32764 IN denotes in
T17382 32758-32761 DT denotes the
T17381 32753-32757 IN denotes with
T17380 32744-32752 RB denotes Together
T17379 32742-32743 . denotes .
T17378 32730-32742 NN denotes carbohydrate
T17377 32723-32729 JJ denotes fungal
T17376 32721-32722 DT denotes a
T17375 32718-32720 IN denotes by
T17374 32703-32717 RB denotes differentially
T17373 32693-32702 VBN denotes regulated
T17372 32690-32692 VB denotes be
T17371 32686-32689 MD denotes can
T17370 32680-32685 WDT denotes which
T17369 32678-32679 , denotes ,
T17368 32677-32678 -RRB- denotes )
T17367 32676-32677 CD denotes 8
T17366 32671-32675 FW denotes Fig.
T17365 32670-32671 -LRB- denotes (
T17364 32661-32669 NN denotes promoter
T17363 32654-32660 NN denotes IL-1RA
T17362 32650-32653 DT denotes the
T17361 32647-32649 IN denotes in
T17360 32641-32646 NNS denotes sites
T10967 21967-21969 TO denotes to
T10966 21959-21966 NNS denotes factors
T10965 21945-21958 NN denotes transcription
T10964 21941-21944 DT denotes the
T10963 21938-21940 IN denotes of
T10962 21929-21937 NN denotes activity
T10961 21921-21928 JJ denotes binding
T10960 21906-21920 JJ denotes down-regulated
T10959 21904-21905 DT denotes a
T10958 21901-21903 TO denotes to
T10957 21893-21900 VBG denotes leading
T10956 21891-21892 , denotes ,
T10955 21889-21891 NNP denotes GP
T10954 21886-21888 IN denotes by
T10953 21876-21885 VBN denotes overruled
T10952 21873-21875 VB denotes be
T10951 21869-21872 RB denotes not
T10950 21863-21868 MD denotes could
T10949 21861-21862 NNP denotes ]
T10948 21859-21861 CD denotes 36
T10947 21858-21859 NNP denotes [
T10946 21854-21857 NNP denotes CHX
T10945 21850-21853 IN denotes via
T10944 21843-21849 NNP denotes NFIL-6
T10943 21839-21842 CC denotes and
T10942 21835-21838 NNP denotes CyA
T10941 21831-21834 IN denotes via
T10940 21826-21830 NNP denotes NFAT
T10996 22114-22119 VBN denotes shown
T10995 22102-22113 RB denotes exemplarily
T10994 22099-22101 VBZ denotes is
T10993 22091-22098 JJ denotes binding
T10992 22082-22090 CD denotes NFATP2/3
T10991 22079-22081 IN denotes in
T10990 22069-22078 NN denotes reduction
T10989 22066-22068 IN denotes of
T10988 22059-22065 NN denotes extent
T10987 22055-22058 DT denotes The
T10986 22053-22054 . denotes .
T10985 22052-22053 -RRB- denotes )
T10984 22051-22052 CD denotes 7
T10983 22046-22050 NN denotes Fig.
T10982 22045-22046 -LRB- denotes (
T10981 22038-22044 NNS denotes levels
T10980 22030-22037 NN denotes protein
T10979 22023-22029 NNP denotes IL-1RA
T10978 22019-22022 CC denotes and
T10977 22014-22018 NNP denotes mRNA
T10976 22007-22013 NNP denotes IL-1RA
T10975 22004-22006 IN denotes of
T10974 21994-22003 NN denotes reduction
T10973 21992-21993 DT denotes a
T10972 21988-21991 CC denotes and
T10971 21986-21987 , denotes ,
T10970 21981-21986 NNS denotes sites
T10969 21974-21980 NN denotes IL-1RA
T10968 21970-21973 DT denotes the
T11063 22411-22412 DT denotes A
T11062 22409-22410 . denotes .
T11061 22407-22409 NNP denotes GP
T11060 22404-22406 IN denotes of
T11059 22402-22403 NN denotes h
T11058 22399-22401 CD denotes 18
T11057 22395-22398 CC denotes and
T11056 22384-22394 NN denotes inhibition
T11055 22382-22383 NN denotes h
T11054 22380-22381 CD denotes 1
T11053 22370-22379 VBG denotes following
T11052 22361-22369 VBN denotes examined
T11051 22357-22360 VBD denotes was
T11050 22352-22356 NNP denotes mRNA
T11049 22350-22351 , denotes ,
T11048 22349-22350 NN denotes h
T11047 22346-22348 CD denotes 24
T11046 22343-22345 IN denotes at
T11045 22337-22342 VBN denotes found
T11044 22333-22336 VBD denotes was
T11043 22326-22332 NN denotes amount
T11042 22319-22325 NN denotes IL-1RA
T11041 22311-22318 JJS denotes highest
T11040 22307-22310 DT denotes the
T11039 22299-22306 IN denotes Because
T11038 22297-22298 . denotes .
T11076 22498-22499 , denotes ,
T11090 22543-22544 . denotes .
T11089 22542-22543 -RRB- denotes )
T11088 22541-22542 LS denotes 4
T11087 22539-22540 SYM denotes =
T11086 22537-22538 FW denotes n
T11085 22536-22537 -LRB- denotes (
T11084 22533-22535 NN denotes 7B
T11083 22528-22532 NNP denotes Fig.
T11082 22525-22527 IN denotes in
T11081 22515-22524 VBN denotes displayed
T11080 22512-22514 VBZ denotes is
T11079 22508-22511 NNP denotes CHX
T11078 22504-22507 CC denotes and
T11077 22500-22503 NNP denotes CyA
T11075 22494-22498 NNP denotes CAPE
T11074 22489-22493 IN denotes with
T11073 22478-22488 NN denotes inhibition
T11072 22472-22477 IN denotes after
T11071 22467-22471 NNP denotes mRNA
T11070 22460-22466 NNP denotes IL-1RA
T11069 22457-22459 IN denotes in
T11068 22448-22456 NN denotes decrease
T11067 22446-22447 DT denotes a
T11066 22432-22445 VBG denotes demonstrating
T11065 22428-22431 NN denotes gel
T11064 22413-22427 JJ denotes representative
T20724 39376-39379 NNP denotes CAG
T20723 39372-39375 NNP denotes CAA
T20722 39368-39371 NNP denotes TTA
T20721 39367-39368 -LRB- denotes (
T20720 39360-39366 NNP denotes NFIL-6
T20719 39356-39359 IN denotes for
T20718 39349-39355 NNS denotes oligos
T20717 39341-39348 VBN denotes mutated
T20716 39331-39340 VBG denotes including
T20715 39329-39330 , denotes ,
T20714 39323-39329 RB denotes before
T20713 39313-39322 VBN denotes described
T20712 39310-39312 IN denotes as
T20711 39307-39309 NNP denotes GP
T20710 39302-39306 IN denotes with
T20709 39291-39301 NN denotes incubation
T20708 39289-39290 NN denotes h
T20707 39287-39288 CD denotes 1
T20706 39281-39286 IN denotes after
T20705 39270-39280 VBN denotes determined
T20704 39265-39269 VBD denotes were
T20703 39258-39264 NNS denotes shifts
T20702 39253-39257 NNP denotes Band
T20743 39451-39454 NNP denotes TTA
T20742 39447-39450 NNP denotes TAT
T20741 39443-39446 NNP denotes AAA
T20740 39439-39442 NNP denotes GTA
T20739 39435-39438 NNP denotes AAG
T20738 39431-39434 NNP denotes GAA
T20737 39427-39430 NNP denotes GCA
T20736 39423-39426 NNP denotes GGC
T20735 39422-39423 -LRB- denotes (
T20734 39413-39421 NNP denotes NFATP2/3
T20733 39409-39412 CC denotes and
T20732 39407-39408 -RRB- denotes )
T20731 39404-39407 NNP denotes GGG
T20730 39400-39403 NNP denotes AGT
T20729 39396-39399 NNP denotes CTT
T20728 39392-39395 NNP denotes ACA
T20727 39388-39391 NNP denotes GCG
T20726 39384-39387 NNP denotes ATT
T20725 39380-39383 NNP denotes TGG
T20071 38167-38172 NNP denotes ELISA
T20070 38164-38166 DT denotes an
T20069 38161-38163 IN denotes by
T20068 38156-38160 NNP denotes IL-8
T20067 38152-38155 CC denotes and
T20066 38145-38151 NNP denotes IL-1RA
T20065 38143-38144 , denotes ,
T20064 38142-38143 -RRB- denotes )
T20063 38135-38142 NNP denotes Austria
T20062 38133-38134 , denotes ,
T20061 38127-38133 NNP denotes Vienna
T20060 38126-38127 -LRB- denotes (
T20059 38118-38125 NNP denotes Systems
T20084 38235-38240 VBG denotes using
T20083 38233-38234 CD denotes 1
T20082 38228-38232 NNP denotes TGFβ
T20081 38224-38227 CC denotes and
T20080 38222-38223 , denotes ,
T20079 38221-38222 -RRB- denotes )
T20078 38214-38221 NNP denotes Germany
T20077 38212-38213 , denotes ,
T20076 38191-38212 NNP denotes Wiesbaden-Nordenstadt
T20075 38190-38191 -LRB- denotes (
T20074 38182-38189 NNP denotes Systems
T20073 38178-38181 NNP denotes R&D
T20072 38173-38177 IN denotes from
T20168 38682-38684 IN denotes in
T20167 38673-38681 VBD denotes observed
T20166 38668-38672 NNP denotes PBMC
T20165 38665-38667 IN denotes of
T20164 38653-38664 NN denotes stimulation
T20163 38648-38652 RB denotes Only
T20162 38646-38647 . denotes .
T20161 38641-38646 NN denotes curve
T20160 38632-38640 JJ denotes standard
T20159 38628-38631 DT denotes the
T20158 38625-38627 IN denotes of
T20157 38619-38624 NN denotes range
T10020 19738-19747 NN denotes phenotype
T10019 19720-19737 JJ denotes anti-inflammatory
T10018 19717-19719 DT denotes an
T10017 19709-19716 IN denotes towards
T10016 19703-19708 NN denotes ratio
T10015 19696-19702 NN denotes IL-1RA
T10014 19695-19696 NN denotes /
T10013 19690-19695 JJ denotes IL-1β
T10012 19675-19689 JJ denotes TSST-1-induced
T10011 19671-19674 DT denotes the
T10010 19661-19670 VBD denotes modulated
T10009 19658-19660 NNP denotes GP
T7123 14915-14919 NNP denotes IL-8
T7122 14907-14914 IN denotes between
T7128 14940-14941 , denotes ,
T7127 14932-14940 RB denotes Moreover
T7126 14930-14931 . denotes .
T7125 14924-14930 NNP denotes IL-1RA
T7124 14920-14923 CC denotes and
T7327 15852-15853 , denotes ,
T7326 15851-15852 NN denotes h
T7325 15848-15850 CD denotes 36
T7324 15844-15847 CC denotes and
T7323 15842-15843 NN denotes h
T2691 5362-5366 IN denotes from
T2692 5367-5370 DT denotes the
T2693 5371-5375 NNP denotes IL-6
T2694 5376-5384 NN denotes promoter
T2695 5385-5386 NNP denotes [
T2696 5386-5388 CD denotes 13
T2697 5388-5389 NNP denotes ]
T2698 5390-5394 VBD denotes were
T2699 5395-5403 VBN denotes examined
T2700 5403-5404 . denotes .
R7278 T11026 T11030 nmod NFκB,sites
R7279 T11027 T11026 cc and,NFκB
R7280 T11028 T11026 conj NFIL-6,NFκB
R7281 T11029 T11030 amod binding,sites
R7282 T11030 T11024 pobj sites,for
R7283 T11031 T11031 ROOT were,were
R7284 T11032 T11031 acomp similar,were
R7285 T11033 T11036 punct (,shown
R7286 T11034 T11036 nsubjpass data,shown
R7287 T11035 T11036 neg not,shown
R7288 T11036 T11031 parataxis shown,were
R7289 T11037 T11036 punct ),shown
R7290 T11038 T11031 punct .,were
R7291 T11039 T11045 mark Because,found
R7292 T11040 T11043 det the,amount
R7293 T11041 T11043 amod highest,amount
R7294 T11042 T11043 compound IL-1RA,amount
R7295 T11043 T11045 nsubjpass amount,found
R7296 T11044 T11045 auxpass was,found
R7297 T11045 T11052 advcl found,examined
R7298 T11046 T11045 prep at,found
R7299 T11047 T11048 nummod 24,h
R7300 T11048 T11046 pobj h,at
R7301 T11049 T11052 punct ",",examined
R7302 T11050 T11052 nsubjpass mRNA,examined
R7303 T11051 T11052 auxpass was,examined
R7304 T11052 T11052 ROOT examined,examined
R7305 T11053 T11052 prep following,examined
R7306 T11054 T11056 nummod 1,inhibition
R7307 T11055 T11056 compound h,inhibition
R7308 T11056 T11053 pobj inhibition,following
R7309 T11057 T11056 cc and,inhibition
R7310 T11058 T11059 nummod 18,h
R7311 T11059 T11056 conj h,inhibition
R7312 T11060 T11059 prep of,h
R7313 T11061 T11060 pobj GP,of
R7314 T11062 T11052 punct .,examined
R7315 T11063 T11065 det A,gel
R7316 T11064 T11065 compound representative,gel
R7317 T11065 T11081 nsubjpass gel,displayed
R7318 T11066 T11065 acl demonstrating,gel
R7319 T11067 T11068 det a,decrease
R7320 T11068 T11066 dobj decrease,demonstrating
R7321 T11069 T11068 prep in,decrease
R7322 T11070 T11071 compound IL-1RA,mRNA
R7323 T11071 T11069 pobj mRNA,in
R7324 T11072 T11066 prep after,demonstrating
R7325 T11073 T11072 pobj inhibition,after
R7326 T11074 T11073 prep with,inhibition
R7327 T11075 T11074 pobj CAPE,with
R7328 T11076 T11075 punct ",",CAPE
R7329 T11077 T11075 conj CyA,CAPE
R7330 T11078 T11077 cc and,CyA
R7331 T11079 T11077 conj CHX,CyA
R7332 T11080 T11081 auxpass is,displayed
R7333 T11081 T11081 ROOT displayed,displayed
R7334 T11082 T11081 prep in,displayed
R7335 T11083 T11084 compound Fig.,7B
R7336 T11084 T11082 pobj 7B,in
R7337 T11085 T11088 punct (,4
R7338 T11086 T11087 advmod n,=
R7339 T11087 T11088 punct =,4
R7340 T11088 T11081 parataxis 4,displayed
R7341 T11089 T11088 punct ),4
R7342 T11090 T11081 punct .,displayed
R7343 T11091 T11104 prep In,shown
R7344 T11092 T11091 pobj addition,In
R7345 T11093 T11104 punct ",",shown
R7346 T11094 T11097 amod corresponding,levels
R7347 T11095 T11097 compound IL-1RA,levels
R7348 T11096 T11097 compound protein,levels
R7349 T11097 T11104 nsubjpass levels,shown
R7350 T11098 T11097 prep after,levels
R7351 T11099 T11100 nummod 24,h
R7352 T11100 T11098 pobj h,after
R7353 T11101 T11100 prep of,h
R7354 T11102 T11101 pobj GP,of
R7355 T11103 T11104 auxpass are,shown
R7356 T11104 T11104 ROOT shown,shown
R7357 T11105 T11104 prep in,shown
R7358 T11106 T11107 compound Fig.,7C
R7359 T11107 T11105 pobj 7C,in
R7360 T11108 T11111 punct (,3
R7361 T11109 T11111 advmod n,3
R7362 T11110 T11111 punct =,3
R7363 T11111 T11107 appos 3,7C
R7364 T11112 T11111 punct ),3
R7365 T11113 T11104 punct .,shown
R7366 T11114 T11120 advmod Altogether,was
R7367 T11115 T11120 punct ",",was
R7368 T11116 T11117 compound NFκB,inhibition
R7369 T11117 T11120 nsubj inhibition,was
R7370 T11118 T11117 prep by,inhibition
R7371 T11119 T11118 pobj CAPE,by
R7372 T11120 T11120 ROOT was,was
R7373 T11121 T11122 advmod more,pronounced
R7374 T11122 T11120 acomp pronounced,was
R7375 T11123 T11120 prep at,was
R7376 T11124 T11126 det the,activity
R7377 T11125 T11126 amod binding,activity
R7378 T11126 T11123 pobj activity,at
R7379 T11127 T11120 cc and,was
R7380 T11128 T11129 det the,transcription
R7381 T11129 T11120 conj transcription,was
R7382 T11130 T11120 punct ",",was
R7383 T11131 T11136 mark whereas,led
R7384 T11132 T11136 nsubj CyA,led
R7385 T11133 T11132 cc and,CyA
R7386 T11134 T11132 conj CHX,CyA
R7387 T11135 T11136 advmod mainly,led
R7388 T11136 T11120 advcl led,was
R7389 T11137 T11136 prep to,led
R7390 T11138 T11141 det a,release
R7391 T11139 T11141 amod decreased,release
R7392 T11140 T11141 compound IL-1RA,release
R7393 T11141 T11137 pobj release,to
R7394 T11142 T11120 punct .,was
R9732 T14815 T14816 compound Animal,models
R9733 T14816 T14822 nsubj models,suggest
R9735 T14817 T14816 prep of,models
R9736 T14818 T14817 pobj sepsis,of
R9737 T14819 T14818 cc and,sepsis
R9739 T14820 T14821 amod myocardial,injury
R9740 T14821 T14818 conj injury,sepsis
R9741 T14822 T14822 ROOT suggest,suggest
R9742 T14823 T14830 mark that,mediates
R9743 T14824 T14827 det a,3-D-glucan
R9744 T14825 T14827 amod β-1,3-D-glucan
R9745 T14826 T14827 compound →,3-D-glucan
R9746 T14827 T14830 nsubj 3-D-glucan,mediates
R9747 T14828 T14830 mark like,mediates
R9748 T14829 T14830 nsubj GP,mediates
R9749 T14830 T14822 ccomp mediates,suggest
R9750 T14831 T14833 poss its,mechanisms
R9751 T14832 T14833 amod protective,mechanisms
R9752 T14833 T14830 dobj mechanisms,mediates
R9753 T14834 T14833 punct ",",mechanisms
R9754 T14835 T14830 prep in,mediates
R9755 T14836 T14835 pobj part,in
R9756 T14837 T14822 punct ",",suggest
R9757 T14838 T14822 prep via,suggest
R9758 T14839 T14841 det a,shift
R9759 T14840 T14841 amod rapid,shift
R9760 T14841 T14838 pobj shift,via
R9761 T14842 T14841 prep from,shift
R9762 T14843 T14842 pobj NFκB,from
R9763 T14844 T14822 punct -,suggest
R9764 T14845 T14846 aux to,PI3K-signaling
R9765 T14846 T14822 xcomp PI3K-signaling,suggest
R9767 T14847 T14849 compound [,]
R9768 T14848 T14849 compound "22,37",]
R9769 T14849 T14846 appos ],PI3K-signaling
R9770 T14850 T14822 punct .,suggest
R9771 T14851 T14852 poss Our,study
R9773 T14852 T14853 nsubj study,provides
R9774 T14853 T14853 ROOT provides,provides
R9775 T14854 T14855 amod novel,evidence
R9776 T14855 T14853 dobj evidence,provides
R9777 T14856 T14873 mark that,switched
R9779 T14857 T14868 amod downstream,expression
R9780 T14858 T14857 prep of,downstream
R9781 T14859 T14858 pobj recognition,of
R9782 T14860 T14857 cc and,downstream
R9784 T14861 T14868 amod signaling,expression
R9786 T14862 T14864 amod pro-inflammatory,factor
R9787 T14863 T14864 compound transcription,factor
R9788 T14864 T14865 nsubj factor,binding
R9789 T14865 T14861 ccomp binding,signaling
R9790 T14866 T14865 cc and,binding
R9791 T14867 T14865 conj cytokine,binding
R9792 T14868 T14873 nsubjpass expression,switched
R9794 T14869 T14868 prep of,expression
R9795 T14870 T14871 amod human,leukocytes
R9796 T14871 T14869 pobj leukocytes,of
R9799 T14872 T14873 auxpass is,switched
R9800 T14873 T14855 acl switched,evidence
R9801 T14874 T14873 prep to,switched
R9802 T14875 T14877 det an,phenotype
R9803 T14876 T14877 amod anti-inflammatory,phenotype
R9804 T14877 T14874 pobj phenotype,to
R9806 T14878 T14877 prep by,phenotype
R9807 T14879 T14878 pobj GP,by
R9808 T14880 T14853 punct .,provides
R9809 T14881 T14882 nsubj We,confirmed
R9810 T14882 T14882 ROOT confirmed,confirmed
R9811 T14969 T14968 punct ",",response
R9812 T14883 T14882 cc and,confirmed
R9813 T14884 T14882 conj extended,confirmed
R9814 T14885 T14886 amod previous,results
R9815 T14886 T14884 dobj results,extended
R9816 T14887 T14889 compound [,]
R9817 T14888 T14889 compound 13-16,]
R9818 T14889 T14884 oprd ],extended
R9819 T14890 T14884 conj indicating,extended
R9820 T14891 T14903 mark that,induced
R9821 T14892 T14903 punct ",",induced
R9822 T14893 T14903 prep in,induced
R9823 T14894 T14895 det the,absence
R9824 T14895 T14893 pobj absence,in
R9825 T14896 T14895 prep of,absence
R9826 T14970 T14971 advmod namely,IL-8
R9827 T14897 T14898 amod other,stimuli
R9828 T14898 T14896 pobj stimuli,of
R9829 T14899 T14898 punct ",",stimuli
R9830 T14971 T14968 appos IL-8,response
R9831 T14900 T14902 amod β-1,3-D-glucans
R9832 T14901 T14902 compound →,3-D-glucans
R9833 T14902 T14903 nsubj 3-D-glucans,induced
R9834 T14972 T14968 cc and,response
R9835 T14903 T14890 ccomp induced,indicating
R9836 T14904 T14903 advmod binding,induced
R9837 T14905 T14904 prep of,binding
R9838 T14973 T14968 conj IL-1RA,response
R9839 T14906 T14905 pobj NFκB,of
R9840 T14907 T14903 punct -,induced
R9841 T14908 T14903 punct ",",induced
R9842 T14974 T14976 punct (,3B
R9843 T14909 T14914 nsubj NFIL-6,cytokine
R9844 T14910 T14909 punct -,NFIL-6
R9845 T14911 T14909 cc and,NFIL-6
R9846 T14975 T14976 compound Fig.,3B
R9847 T14912 T14909 conj NFAT-mers,NFIL-6
R9848 T14913 T14914 aux to,cytokine
R9849 T14914 T14903 advcl cytokine,induced
R9850 T14976 T14973 appos 3B,IL-1RA
R9851 T14915 T14914 dobj promoters,cytokine
R9852 T14916 T14882 punct .,confirmed
R9853 T14977 T14976 punct ),3B
R9854 T14917 T14934 prep Because,speculate
R9855 T14918 T14917 pcomp of,Because
R9856 T14919 T14922 det the,shifts
R9857 T14920 T14922 amod multiple,shifts
R9858 T14921 T14922 compound band,shifts
R9859 T14922 T14917 pobj shifts,Because
R9860 T14923 T14922 acl observed,shifts
R9861 T14978 T14961 punct .,transformed
R9862 T14924 T14923 prep for,observed
R9863 T14925 T14934 nsubj NFAT,speculate
R9864 T14926 T14934 amod binding,speculate
R9865 T14979 T14983 advmod Hence,are
R9866 T14927 T14929 punct (,1A
R9867 T14928 T14929 compound Fig.,1A
R9868 T14929 T14926 appos 1A,binding
R9869 T14980 T14983 punct ",",are
R9870 T14930 T14929 punct ),1A
R9871 T14931 T14934 punct ",",speculate
R9872 T14932 T14934 nsubj one,speculate
R9873 T14981 T14982 poss our,data
R9874 T14933 T14934 aux could,speculate
R9875 T14934 T14934 ROOT speculate,speculate
R9876 T14935 T14937 mark that,is
R9877 T14982 T14983 nsubj data,are
R9878 T14936 T14937 expl there,is
R9879 T14937 T14934 ccomp is,speculate
R9880 T14938 T14937 attr activation,is
R9881 T14983 T14983 ROOT are,are
R9882 T14939 T14938 prep of,activation
R9883 T14940 T14943 amod several,isoforms
R9884 T14941 T14943 amod different,isoforms
R9885 T14984 T14983 prep in,are
R9886 T14942 T14943 compound NFAT,isoforms
R9887 T14943 T14939 pobj isoforms,of
R9888 T14985 T14984 pobj aggreement,in
R9889 T14944 T14938 punct ",",activation
R9890 T14945 T14946 advmod probably,derived
R9891 T14946 T14938 acl derived,activation
R9892 T14986 T14983 prep with,are
R9893 T14947 T14946 prep from,derived
R9894 T14987 T14989 det the,reports
R9895 T14948 T14949 amod alternative,splicing
R9896 T14949 T14947 pobj splicing,from
R9897 T14988 T14989 amod few,reports
R9898 T14950 T14952 nmod [,]
R9899 T14951 T14952 nummod 38,]
R9900 T14952 T14949 nmod ],splicing
R9901 T14989 T14986 pobj reports,with
R9902 T14953 T14934 punct .,speculate
R9903 T14954 T14961 advmod Interestingly,transformed
R9904 T14955 T14961 punct ",",transformed
R9905 T14956 T14959 det the,factor
R9906 T14957 T14959 amod GP-induced,factor
R9907 T14990 T14989 acl describing,reports
R9908 T14958 T14959 compound transcription,factor
R9909 T14959 T14961 nsubj factor,transformed
R9910 T14960 T14961 advmod binding,transformed
R9911 T14961 T14961 ROOT transformed,transformed
R9912 T14991 T14995 det a,IL-8
R9913 T14962 T14963 advmod only,into
R9914 T14963 T14961 prep into,transformed
R9915 T14964 T14968 det a,response
R9916 T14992 T14995 amod β-1,IL-8
R9917 T14965 T14966 advmod very,limited
R9918 T14966 T14968 amod limited,response
R9919 T14967 T14968 compound cytokine,response
R9920 T14993 T14995 nmod →,IL-8
R9921 T14968 T14963 pobj response,into
R9922 T14994 T14995 amod 3-D-glucan-mediated,IL-8
R9923 T14995 T14990 dobj IL-8,describing
R9924 T15066 T15067 nummod p65/65,homodimer
R9925 T14996 T14998 compound [,]
R9926 T15067 T15063 pobj homodimer,via
R9927 T15068 T15067 punct ",",homodimer
R9928 T14997 T14998 compound "6,16,19",]
R9929 T15069 T15070 advmod rather,than
R9930 T14998 T14995 appos ],IL-8
R9931 T14999 T14998 cc and,]
R9932 T15070 T15060 cc than,depending
R9933 T15000 T15001 compound IL-1RA,production
R9934 T15071 T15053 prep via,pointed
R9935 T15072 T15073 nummod p65/50,heterodimers
R9936 T15073 T15071 pobj heterodimers,via
R9937 T15001 T15002 compound production,[
R9938 T15074 T15073 punct ",",heterodimers
R9939 T15075 T15077 nsubj which,be
R9940 T15076 T15077 aux might,be
R9941 T15002 T14998 conj [,]
R9942 T15077 T15073 relcl be,heterodimers
R9943 T15078 T15079 det the,case
R9944 T15079 T15077 attr case,be
R9945 T15003 T15004 nummod 17,]
R9946 T15080 T15079 prep for,case
R9947 T15081 T15084 det the,transcription
R9948 T15082 T15084 amod GP-mediated,transcription
R9949 T15004 T15002 appos ],[
R9950 T15083 T15084 compound IL-8,transcription
R9951 T15084 T15080 pobj transcription,for
R9952 T15085 T15053 punct .,pointed
R9953 T15086 T15089 det A,transcription
R9954 T15005 T14983 punct .,are
R9955 T15087 T15089 amod GP-mediated,transcription
R9956 T15088 T15089 compound IL-8,transcription
R9957 T15089 T15114 nsubj transcription,seems
R9958 T15090 T15089 acl based,transcription
R9959 T15091 T15090 prep upon,based
R9960 T15092 T15093 det a,cooperation
R9961 T15093 T15091 pobj cooperation,upon
R9962 T15006 T15014 prep In,demonstrated
R9963 T15094 T15093 prep between,cooperation
R9964 T15095 T15096 compound transactivated,NFκB
R9965 T15096 T15094 pobj NFκB,between
R9966 T15007 T15006 pobj addition,In
R9967 T15097 T15096 nummod p65,NFκB
R9968 T15098 T15096 cc and,NFκB
R9969 T15099 T15100 compound NFIL-6,[
R9970 T15008 T15014 punct ",",demonstrated
R9971 T15100 T15096 conj [,NFκB
R9972 T15101 T15102 compound "13,39",]
R9973 T15102 T15096 conj ],NFκB
R9974 T15009 T15010 poss our,EMSA/supershift
R9975 T15103 T15102 cc or,]
R9976 T15104 T15102 conj NFATc2,]
R9977 T15105 T15106 advmod dimer,binding
R9978 T15010 T15014 nsubj EMSA/supershift,demonstrated
R9979 T15011 T15010 cc and,EMSA/supershift
R9980 T15106 T15093 amod binding,cooperation
R9981 T15107 T15106 prep to,binding
R9982 T15012 T15013 compound immunoblotting,results
R9983 T15108 T15110 det the,site
R9984 T15109 T15110 compound IL-8κB,site
R9985 T15110 T15107 pobj site,to
R9986 T15111 T15113 compound [,]
R9987 T15013 T15010 conj results,EMSA/supershift
R9988 T15112 T15113 compound 38,]
R9989 T15113 T15114 nsubj ],seems
R9990 T15114 T15114 ROOT seems,seems
R9991 T15014 T15014 ROOT demonstrated,demonstrated
R9992 T15115 T15116 advmod also,possible
R9993 T15116 T15114 oprd possible,seems
R9994 T15015 T15017 det a,predominant
R9995 T15117 T15114 punct .,seems
R9996 T15118 T15121 det The,site
R9997 T15119 T15121 compound IL-8κB,site
R9998 T15120 T15121 compound consensus,site
R9999 T15016 T15017 amod GP-mediated,predominant
R10000 T15121 T15122 nsubj site,exhibits
R10001 T15122 T15122 ROOT exhibits,exhibits
R10002 T15123 T15128 det a,site
R10003 T15017 T15018 amod predominant,binding
R10004 T15124 T15125 advmod preferentially,p65
R10005 T15125 T15128 amod p65,site
R10006 T15126 T15128 amod binding,site
R10007 T15127 T15128 compound half,site
R10008 T15128 T15122 dobj site,exhibits
R10009 T15129 T15122 cc and,exhibits
R10010 T15018 T15014 dobj binding,demonstrated
R10011 T15130 T15131 advmod thus,differs
R10012 T15131 T15122 conj differs,exhibits
R10013 T15132 T15131 prep from,differs
R10014 T15019 T15018 prep of,binding
R10015 T15133 T15136 det the,site
R10016 T15134 T15136 compound κB,site
R10017 T15135 T15136 compound half,site
R10018 T15136 T15132 pobj site,from
R10019 T15020 T15019 pobj NFκB,of
R10020 T15137 T15136 acl described,site
R10021 T15138 T15137 prep for,described
R10022 T15139 T15138 pobj TNFα,for
R10023 T15021 T15020 nummod p65,NFκB
R10024 T15140 T15139 cc and,TNFα
R10025 T15141 T15142 compound IL-1β,[
R10026 T15142 T15139 conj [,TNFα
R10027 T15022 T15014 cc and,demonstrated
R10028 T15143 T15144 compound "27,40",]
R10029 T15144 T15139 conj ],TNFα
R10030 T15023 T15014 conj to,demonstrated
R10031 T15145 T15131 punct ",",differs
R10032 T15146 T15131 advcl supporting,differs
R10033 T15147 T15148 det the,idea
R10034 T15024 T15026 det a,extent
R10035 T15148 T15146 dobj idea,supporting
R10036 T15149 T15148 prep of,idea
R10037 T15150 T15149 pcomp regulating,of
R10038 T15025 T15026 amod lesser,extent
R10039 T15151 T15150 dobj NFκB,regulating
R10040 T15152 T15150 oprd binding,regulating
R10041 T15026 T15023 pobj extent,to
R10042 T15153 T15150 prep through,regulating
R10043 T15154 T15155 amod combinatorial,associations
R10044 T15155 T15153 pobj associations,through
R10045 T15027 T15026 prep of,extent
R10046 T15156 T15155 prep of,associations
R10047 T15157 T15158 det the,subunits
R10048 T15158 T15156 pobj subunits,of
R10049 T15028 T15027 pobj p50,of
R10050 T15159 T15158 cc and,subunits
R10051 T15160 T15162 det the,sequence
R10052 T15161 T15162 amod specific,sequence
R10053 T15162 T15150 dobj sequence,regulating
R10054 T15029 T15023 prep to,to
R10055 T15030 T15033 det a,site
R10056 T15031 T15033 amod κB,site
R10057 T15163 T15162 prep of,sequence
R10058 T15164 T15167 det the,motif
R10059 T15165 T15167 amod decameric,motif
R10060 T15032 T15033 compound consensus,site
R10061 T15166 T15167 compound κB,motif
R10062 T15167 T15163 pobj motif,of
R10063 T15168 T15170 compound [,]
R10064 T15033 T15029 pobj site,to
R10065 T15169 T15170 compound "41,42",]
R10066 T15170 T15167 appos ],motif
R10067 T15171 T15131 punct .,differs
R10068 T15034 T15033 prep of,site
R10069 T15172 T15178 prep Unlike,found
R10070 T15173 T15172 pobj LPS,Unlike
R10071 T15174 T15173 cc or,LPS
R10072 T15035 T15037 det the,promoter
R10073 T15175 T15173 conj TSST-1,LPS
R10074 T15176 T15178 punct ",",found
R10075 T15177 T15178 nsubj we,found
R10076 T15036 T15037 compound IL-8,promoter
R10077 T15178 T15178 ROOT found,found
R10078 T15179 T15183 mark that,induce
R10079 T15180 T15183 nsubj GP,induce
R10080 T15037 T15034 pobj promoter,of
R10081 T15181 T15183 aux did,induce
R10082 T15182 T15183 neg not,induce
R10083 T15183 T15178 ccomp induce,found
R10084 T15038 T15037 punct (,promoter
R10085 T15184 T15183 dobj IL-1β,induce
R10086 T15039 T15040 compound Figs.,1A
R10087 T15040 T15037 appos 1A,promoter
R10088 T15185 T15178 punct ",",found
R10089 T15186 T15178 cc but,found
R10090 T15041 T15040 punct ",",1A
R10091 T15187 T15189 nsubj it,induced
R10092 T15188 T15189 advmod strongly,induced
R10093 T15189 T15178 conj induced,found
R10094 T15042 T15040 nummod 2,1A
R10095 T15190 T15189 dobj IL-1RA,induced
R10096 T15191 T15189 punct ",",induced
R10097 T15192 T15189 advcl suggesting,induced
R10098 T15043 T15037 punct ),promoter
R10099 T15193 T15196 det an,potential
R10100 T15194 T15196 amod immediate,potential
R10101 T15044 T15014 punct .,demonstrated
R10102 T15195 T15196 amod anti-inflammatory,potential
R10103 T15196 T15192 dobj potential,suggesting
R10104 T15197 T15196 prep of,potential
R10105 T15045 T15053 nsubj Results,pointed
R10106 T15198 T15197 pobj GP,of
R10107 T15199 T15189 punct .,induced
R10108 T15200 T15209 advcl Analysing,discovered
R10109 T15201 T15203 det the,promoter
R10110 T15202 T15203 compound IL-1RA,promoter
R10111 T15203 T15200 dobj promoter,Analysing
R10112 T15046 T15045 prep by,Results
R10113 T15204 T15206 nmod [,]
R10114 T15205 T15206 nummod 34,]
R10115 T15206 T15203 appos ],promoter
R10116 T15047 T15046 pobj Schulte,by
R10117 T15207 T15209 punct ",",discovered
R10118 T15208 T15209 nsubj we,discovered
R10119 T15209 T15209 ROOT discovered,discovered
R10120 T15048 T15047 cc and,Schulte
R10121 T15210 T15213 nummod four,sites
R10122 T15211 T15213 amod new,sites
R10123 T15212 T15213 amod binding,sites
R10124 T15213 T15209 dobj sites,discovered
R10125 T15049 T15047 conj colleagues,Schulte
R10126 T15214 T15213 punct (,sites
R10127 T15215 T15217 nmod Fig.,)
R10128 T15216 T15215 nummod 8,Fig.
R10129 T15050 T15052 compound [,]
R10130 T15217 T15213 punct ),sites
R10131 T15218 T15213 punct :,sites
R10132 T15219 T15221 det an,site
R10133 T15051 T15052 compound 28,]
R10134 T15220 T15221 amod NFκB3,site
R10135 T15221 T15213 appos site,sites
R10136 T15222 T15221 punct (,site
R10137 T15052 T15049 appos ],colleagues
R10138 T15223 T15221 prep between,site
R10139 T15224 T15223 pobj -100,between
R10140 T15053 T15053 ROOT pointed,pointed
R10141 T15225 T15224 cc and,-100
R10142 T15226 T15224 conj -130,-100
R10143 T15227 T15221 punct ),site
R10144 T15054 T15053 prep to,pointed
R10145 T15228 T15221 punct ",",site
R10146 T15229 T15232 det an,site
R10147 T15230 T15232 compound NFκB,site
R10148 T15055 T15056 det an,induction
R10149 T15231 T15232 compound consensus,site
R10150 T15232 T15221 conj site,site
R10151 T15233 T15232 punct (,site
R10152 T15056 T15054 pobj induction,to
R10153 T15234 T15232 appos -266,site
R10154 T15235 T15232 cc and,site
R10155 T15057 T15056 prep of,induction
R10156 T15236 T15232 conj -280,site
R10157 T15237 T15213 punct ),sites
R10158 T15238 T15213 punct ",",sites
R10159 T15239 T15243 det another,site
R10160 T15240 T15241 compound NFκB2,/
R10161 T15241 T15243 nmod /,site
R10162 T15242 T15241 nummod 3,/
R10163 T15058 T15059 compound IL-8,transcription
R10164 T15243 T15213 appos site,sites
R10165 T15244 T15243 punct (,site
R10166 T15245 T15243 appos -288,site
R10167 T15059 T15057 pobj transcription,of
R10168 T15246 T15243 cc and,site
R10169 T15247 T15243 conj -302,site
R10170 T15248 T15243 punct ),site
R10171 T15060 T15053 prep depending,pointed
R10172 T15249 T15243 cc and,site
R10173 T15250 T15254 det a,site
R10174 T15251 T15252 advmod more,distal
R10175 T15061 T15060 prep on,depending
R10176 T15252 T15254 amod distal,site
R10177 T15253 T15254 nummod NFATP2/3,site
R10178 T15254 T15243 conj site,site
R10179 T15062 T15061 pobj activation,on
R10180 T15255 T15254 punct (,site
R10181 T15256 T15254 appos -471,site
R10182 T15257 T15256 cc and,-471
R10183 T15258 T15256 conj -490,-471
R10184 T15063 T15060 prep via,depending
R10185 T15259 T15254 punct ),site
R10186 T15064 T15067 det an,homodimer
R10187 T15065 T15067 nmod NFκB,homodimer
R10188 T15260 T15209 punct .,discovered
R10189 T15357 T15356 prep of,induction
R10190 T15261 T15262 poss Our,data
R10191 T15262 T15263 nsubj data,indicated
R10192 T15358 T15357 pobj IL-1RA,of
R10193 T15263 T15263 ROOT indicated,indicated
R10194 T15264 T15266 mark that,leads
R10195 T15265 T15266 nsubj GP,leads
R10196 T15359 T15358 punct (,IL-1RA
R10197 T15266 T15263 ccomp leads,indicated
R10198 T15267 T15266 prep to,leads
R10199 T15268 T15267 pobj production,to
R10200 T15360 T15358 appos Fig.,IL-1RA
R10201 T15269 T15268 prep of,production
R10202 T15270 T15269 pobj IL-1RA,of
R10203 T15271 T15272 advmod primarily,via
R10204 T15361 T15360 nummod 7,Fig.
R10205 T15272 T15266 prep via,leads
R10206 T15273 T15272 pobj induction,via
R10207 T15274 T15273 prep of,induction
R10208 T15275 T15274 pobj NFATP2/3,of
R10209 T15276 T15275 cc and,NFATP2/3
R10210 T15362 T15358 punct ),IL-1RA
R10211 T15277 T15278 compound NFIL-6,DNA
R10212 T15278 T15275 conj DNA,NFATP2/3
R10213 T15279 T15272 conj binding,via
R10214 T15363 T15344 punct .,suggest
R10215 T15280 T15266 punct ",",leads
R10216 T15281 T15283 nsubj which,be
R10217 T15282 T15283 aux might,be
R10218 T15364 T15377 prep Regarding,reported
R10219 T15283 T15266 advcl be,leads
R10220 T15284 T15283 acomp due,be
R10221 T15285 T15284 prep to,due
R10222 T15365 T15366 amod cellular,sources
R10223 T15286 T15285 pobj differences,to
R10224 T15287 T15286 prep in,differences
R10225 T15288 T15290 det the,motif
R10226 T15366 T15364 pobj sources,Regarding
R10227 T15289 T15290 amod binding,motif
R10228 T15290 T15287 pobj motif,in
R10229 T15291 T15290 cc or,motif
R10230 T15367 T15377 punct ",",reported
R10231 T15292 T15293 det the,composition
R10232 T15293 T15290 conj composition,motif
R10233 T15368 T15370 preconj both,monocytes
R10234 T15294 T15293 prep of,composition
R10235 T15295 T15298 det the,factors
R10236 T15296 T15298 amod activated,factors
R10237 T15369 T15370 punct ",",monocytes
R10238 T15297 T15298 compound transcription,factors
R10239 T15298 T15294 pobj factors,of
R10240 T15299 T15300 punct (,NFAT
R10241 T15370 T15377 nsubjpass monocytes,reported
R10242 T15300 T15298 appos NFAT,factors
R10243 T15301 T15298 punct ),factors
R10244 T15302 T15293 prep between,composition
R10245 T15303 T15304 det the,IFNγ
R10246 T15371 T15373 advmod as,as
R10247 T15304 T15302 pobj IFNγ,between
R10248 T15305 T15304 punct ",",IFNγ
R10249 T15306 T15304 conj IL-6,IFNγ
R10250 T15372 T15373 advmod well,as
R10251 T15307 T15306 cc and,IL-6
R10252 T15308 T15306 conj IL-1RA,IL-6
R10253 T15309 T15304 conj promoter,IFNγ
R10254 T15373 T15370 cc as,monocytes
R10255 T15310 T15263 punct .,indicated
R10256 T15311 T15313 det The,decrease
R10257 T15312 T15313 compound differential,decrease
R10258 T15313 T15320 nsubj decrease,binding
R10259 T15314 T15313 prep of,decrease
R10260 T15315 T15314 pobj NFκB,of
R10261 T15374 T15370 conj neutrophils,monocytes
R10262 T15316 T15315 punct ",",NFκB
R10263 T15317 T15315 conj NFAT,NFκB
R10264 T15318 T15317 cc and,NFAT
R10265 T15375 T15377 aux have,reported
R10266 T15319 T15317 conj NFIL-6,NFAT
R10267 T15320 T15320 ROOT binding,binding
R10268 T15321 T15320 prep to,binding
R10269 T15376 T15377 auxpass been,reported
R10270 T15322 T15321 pobj sites,to
R10271 T15323 T15322 prep in,sites
R10272 T15377 T15377 ROOT reported,reported
R10273 T15324 T15326 det the,promoter
R10274 T15325 T15326 compound IL-1RA,promoter
R10275 T15326 T15323 pobj promoter,in
R10276 T15378 T15379 aux to,produce
R10277 T15327 T15329 advmod as,as
R10278 T15328 T15329 advmod well,as
R10279 T15329 T15320 prep as,binding
R10280 T15379 T15377 xcomp produce,reported
R10281 T15330 T15320 prep of,binding
R10282 T15331 T15332 compound IL-1RA,mRNA
R10283 T15332 T15330 pobj mRNA,of
R10284 T15380 T15381 compound IL-1RA,[
R10285 T15333 T15332 cc and,mRNA
R10286 T15334 T15344 nsubj protein,suggest
R10287 T15335 T15334 acl induced,protein
R10288 T15336 T15335 agent by,induced
R10289 T15381 T15379 dobj [,produce
R10290 T15337 T15338 amod selective,inhibitors
R10291 T15338 T15336 pobj inhibitors,by
R10292 T15339 T15335 advmod prior,induced
R10293 T15382 T15383 nummod 32,]
R10294 T15340 T15335 prep to,induced
R10295 T15341 T15342 compound GP,treatment
R10296 T15383 T15381 appos ],[
R10297 T15384 T15377 punct .,reported
R10298 T15342 T15340 pobj treatment,to
R10299 T15343 T15344 aux might,suggest
R10300 T15344 T15320 conj suggest,binding
R10301 T15385 T15387 amod Flow,experiments
R10302 T15345 T15349 mark that,linked
R10303 T15346 T15347 det these,steps
R10304 T15347 T15349 nsubjpass steps,linked
R10305 T15386 T15387 compound cytometric,experiments
R10306 T15348 T15349 auxpass are,linked
R10307 T15349 T15344 ccomp linked,suggest
R10308 T15350 T15349 prep to,linked
R10309 T15351 T15352 det each,other
R10310 T15352 T15350 pobj other,to
R10311 T15387 T15388 nsubj experiments,seemed
R10312 T15353 T15349 cc and,linked
R10313 T15354 T15349 conj necessary,linked
R10314 T15355 T15354 prep for,necessary
R10315 T15356 T15355 pobj induction,for
R10316 T15388 T15388 ROOT seemed,seemed
R10317 T15389 T15390 aux to,confirm
R10318 T15390 T15388 xcomp confirm,seemed
R10319 T15391 T15395 mark that,were
R10320 T15392 T15395 nsubj monocytes,were
R10321 T15393 T15392 cc and,monocytes
R10322 T15454 T15453 nummod 4,receptor
R10323 T15455 T15453 cc and,receptor
R10324 T15394 T15392 conj neutrophils,monocytes
R10325 T15456 T15457 amod subsequent,signaling
R10326 T15457 T15453 conj signaling,receptor
R10327 T15395 T15390 ccomp were,confirm
R10328 T15458 T15457 prep via,signaling
R10329 T15459 T15461 det the,pathway
R10330 T15460 T15461 compound NFκB,pathway
R10331 T15396 T15395 acomp able,were
R10332 T15461 T15458 pobj pathway,via
R10333 T15462 T15457 punct ",",signaling
R10334 T15397 T15398 aux to,produce
R10335 T15463 T15450 advcl leading,mediated
R10336 T15464 T15463 prep to,leading
R10337 T15465 T15464 pobj expression,to
R10338 T15398 T15396 xcomp produce,able
R10339 T15466 T15465 prep of,expression
R10340 T15467 T15468 amod pro-inflammatory,mediators
R10341 T15399 T15398 dobj IL-8,produce
R10342 T15468 T15466 pobj mediators,of
R10343 T15469 T15468 prep like,mediators
R10344 T15470 T15471 compound TNFα,[
R10345 T15400 T15410 advmod just,shown
R10346 T15471 T15469 pobj [,like
R10347 T15472 T15473 nummod 43,]
R10348 T15473 T15471 appos ],[
R10349 T15401 T15410 mark as,shown
R10350 T15474 T15450 punct .,mediated
R10351 T15475 T15477 det A,superantigen
R10352 T15402 T15410 advcl IL-1RA,shown
R10353 T15476 T15477 amod bacterial,superantigen
R10354 T15477 T15477 ROOT superantigen,superantigen
R10355 T15478 T15477 prep like,superantigen
R10356 T15403 T15402 prep in,IL-1RA
R10357 T15479 T15480 nummod TSST-1,acts
R10358 T15480 T15478 pobj acts,like
R10359 T15481 T15477 prep through,superantigen
R10360 T15482 T15481 amod binding,through
R10361 T15483 T15477 prep to,superantigen
R10362 T15404 T15403 pobj response,in
R10363 T15484 T15485 compound MHC-II,molecules
R10364 T15485 T15483 pobj molecules,to
R10365 T15486 T15483 cc and,to
R10366 T15405 T15404 prep to,response
R10367 T15487 T15491 advmod subsequently,receptor
R10368 T15488 T15491 det the,receptor
R10369 T15489 T15491 compound T,receptor
R10370 T15490 T15491 compound cell,receptor
R10371 T15406 T15405 pobj GP,to
R10372 T15491 T15477 appos receptor,superantigen
R10373 T15492 T15477 punct ",",superantigen
R10374 T15407 T15410 punct (,shown
R10375 T15493 T15477 acl leading,superantigen
R10376 T15494 T15493 prep to,leading
R10377 T15495 T15494 pobj release,to
R10378 T15496 T15495 prep of,release
R10379 T15408 T15410 nsubjpass data,shown
R10380 T15497 T15498 advmod mainly,IFNγ
R10381 T15498 T15496 pobj IFNγ,of
R10382 T15409 T15410 neg not,shown
R10383 T15410 T15388 advcl shown,seemed
R10384 T15499 T15498 cc and,IFNγ
R10385 T15411 T15388 punct ),seemed
R10386 T15500 T15498 conj TNFα,IFNγ
R10387 T15501 T15500 punct ",",TNFα
R10388 T15502 T15503 det the,latter
R10389 T15412 T15388 punct .,seemed
R10390 T15503 T15495 dobj latter,release
R10391 T15504 T15495 prep via,release
R10392 T15505 T15507 preconj both,PI3K
R10393 T15413 T15416 det This,profile
R10394 T15506 T15505 punct ",",both
R10395 T15507 T15504 pobj PI3K,via
R10396 T15414 T15416 amod GP-induced,profile
R10397 T15508 T15507 cc and,PI3K
R10398 T15509 T15511 nummod p38,kinase
R10399 T15415 T15416 compound cytokine,profile
R10400 T15510 T15511 amod mitogen-activated,kinase
R10401 T15511 T15507 conj kinase,PI3K
R10402 T15512 T15511 acl signaling,kinase
R10403 T15416 T15417 nsubj profile,was
R10404 T15513 T15515 compound [,]
R10405 T15514 T15515 compound "44,45",]
R10406 T15515 T15512 dobj ],signaling
R10407 T15417 T15417 ROOT was,was
R10408 T15516 T15477 punct .,superantigen
R10409 T15517 T15537 advmod Altogether,fit
R10410 T15518 T15537 punct ",",fit
R10411 T15519 T15520 det the,induction
R10412 T15520 T15537 nsubj induction,fit
R10413 T15521 T15520 prep of,induction
R10414 T15418 T15420 advmod substantially,restricted
R10415 T15522 T15524 det the,IL-8
R10416 T15523 T15524 compound neutrophil-attracting,IL-8
R10417 T15524 T15521 pobj IL-8,of
R10418 T15419 T15420 advmod more,restricted
R10419 T15525 T15524 cc and,IL-8
R10420 T15526 T15528 det the,IL-1RA
R10421 T15527 T15528 amod anti-inflammatory,IL-1RA
R10422 T15420 T15417 acomp restricted,was
R10423 T15528 T15524 conj IL-1RA,IL-8
R10424 T15529 T15528 prep by,IL-1RA
R10425 T15530 T15531 amod fungal,carbohydrates
R10426 T15531 T15529 pobj carbohydrates,by
R10427 T15532 T15533 punct (,GP
R10428 T15533 T15531 appos GP,carbohydrates
R10429 T15421 T15420 prep than,restricted
R10430 T15534 T15531 punct ),carbohydrates
R10431 T15535 T15537 aux may,fit
R10432 T15536 T15537 advmod well,fit
R10433 T15422 T15421 pobj that,than
R10434 T15537 T15537 ROOT fit,fit
R10435 T15538 T15537 prep to,fit
R10436 T15423 T15422 prep of,that
R10437 T15539 T15542 det a,response
R10438 T15540 T15542 amod benign,response
R10439 T15541 T15542 compound PAMP,response
R10440 T15424 T15423 pobj LPS,of
R10441 T15542 T15538 pobj response,to
R10442 T15543 T15537 punct ",",fit
R10443 T15544 T15537 advcl mounting,fit
R10444 T15425 T15424 cc or,LPS
R10445 T15545 T15546 amod defensive,mechanisms
R10446 T15546 T15544 dobj mechanisms,mounting
R10447 T15426 T15424 conj TSST-1,LPS
R10448 T15547 T15544 prep against,mounting
R10449 T15548 T15551 det a,attack
R10450 T15549 T15551 amod possible,attack
R10451 T15427 T15424 punct ",",LPS
R10452 T15550 T15551 amod microbial,attack
R10453 T15428 T15429 nsubj which,is
R10454 T15429 T15424 relcl is,LPS
R10455 T15551 T15547 pobj attack,against
R10456 T15552 T15537 punct .,fit
R10457 T15430 T15429 acomp likely,is
R10458 T15553 T15555 advmod Potentially,more
R10459 T15554 T15555 advmod even,more
R10460 T15555 T15556 advmod more,relevant
R10461 T15556 T15567 advmod relevant,found
R10462 T15557 T15556 prep than,relevant
R10463 T15431 T15429 prep due,is
R10464 T15558 T15561 det the,panel
R10465 T15559 T15561 amod specific,panel
R10466 T15560 T15561 amod cytokine,panel
R10467 T15561 T15557 pobj panel,than
R10468 T15432 T15431 prep to,due
R10469 T15562 T15561 acl induced,panel
R10470 T15563 T15562 agent by,induced
R10471 T15433 T15432 pobj differences,to
R10472 T15564 T15563 pobj GP,by
R10473 T15565 T15567 punct ",",found
R10474 T15566 T15567 nsubj we,found
R10475 T15434 T15433 prep in,differences
R10476 T15567 T15567 ROOT found,found
R10477 T15568 T15583 mark that,ameliorated
R10478 T15569 T15583 punct ",",ameliorated
R10479 T15435 T15434 pobj recognition,in
R10480 T15570 T15583 prep in,ameliorated
R10481 T15571 T15572 det the,presence
R10482 T15572 T15570 pobj presence,in
R10483 T15436 T15429 cc and,is
R10484 T15573 T15572 prep of,presence
R10485 T15574 T15575 amod other,stimuli
R10486 T15575 T15573 pobj stimuli,of
R10487 T15576 T15575 punct (,stimuli
R10488 T15437 T15422 acl signaling,that
R10489 T15577 T15575 appos LPS,stimuli
R10490 T15438 T15437 prep between,signaling
R10491 T15578 T15577 cc or,LPS
R10492 T15579 T15577 conj TSST-1,LPS
R10493 T15439 T15438 pobj LPS,between
R10494 T15580 T15575 punct ),stimuli
R10495 T15581 T15583 punct ",",ameliorated
R10496 T15582 T15583 nsubj GP,ameliorated
R10497 T15440 T15439 punct ",",LPS
R10498 T15583 T15567 ccomp ameliorated,found
R10499 T15584 T15587 poss their,reactions
R10500 T15585 T15587 amod pro-inflammatory,reactions
R10501 T15441 T15439 conj TSST-1,LPS
R10502 T15586 T15587 amod immune,reactions
R10503 T15587 T15583 dobj reactions,ameliorated
R10504 T15442 T15441 cc and,TSST-1
R10505 T15588 T15587 punct ",",reactions
R10506 T15589 T15587 amod similar,reactions
R10507 T15590 T15589 prep to,similar
R10508 T15591 T15592 det the,effects
R10509 T15443 T15441 conj GP,TSST-1
R10510 T15592 T15590 pobj effects,to
R10511 T15593 T15592 prep in,effects
R10512 T15594 T15595 compound murine,models
R10513 T15595 T15593 pobj models,in
R10514 T15596 T15595 prep of,models
R10515 T15597 T15596 pobj sepsis,of
R10516 T15444 T15417 punct .,was
R10517 T15598 T15597 cc and,sepsis
R10518 T15599 T15597 conj inflammation,sepsis
R10519 T15600 T15602 compound [,]
R10520 T15445 T15450 nsubjpass Recognition,mediated
R10521 T15601 T15602 compound 21-24,]
R10522 T15602 T15595 appos ],models
R10523 T15603 T15567 punct .,found
R10524 T15446 T15445 prep of,Recognition
R10525 T15604 T15607 advmod Mainly,altered
R10526 T15605 T15607 punct ",",altered
R10527 T15606 T15607 nsubj GP,altered
R10528 T15447 T15446 pobj LPS,of
R10529 T15607 T15607 ROOT altered,altered
R10530 T15608 T15613 det the,ratio
R10531 T15609 T15613 amod TSST-1-induced,ratio
R10532 T15448 T15450 auxpass is,mediated
R10533 T15610 T15613 amod IL-1β,ratio
R10534 T15611 T15613 nmod /,ratio
R10535 T15449 T15450 advmod mainly,mediated
R10536 T15612 T15613 compound IL-1RA,ratio
R10537 T15613 T15607 dobj ratio,altered
R10538 T15614 T15613 prep from,ratio
R10539 T15450 T15450 ROOT mediated,mediated
R10540 T15615 T15616 det a,pro-
R10541 T15616 T15614 pobj pro-,from
R10542 T15617 T15607 prep to,altered
R10543 T15618 T15620 det an,profile
R10544 T15451 T15450 prep through,mediated
R10545 T15619 T15620 amod anti-inflammatory,profile
R10546 T15620 T15617 pobj profile,to
R10547 T15452 T15453 amod Toll-like,receptor
R10548 T15621 T15620 prep via,profile
R10549 T15622 T15621 pobj down-regulation,via
R10550 T15623 T15622 prep of,down-regulation
R10551 T15453 T15451 pobj receptor,through
R10552 T15624 T15623 pobj IL-1β,of
R10553 T15625 T15624 cc and,IL-1β
R10554 T15648 T15647 agent by,caused
R10555 T15626 T15624 conj IL-6,IL-1β
R10556 T15627 T15607 punct ",",altered
R10557 T15628 T15607 prep at,altered
R10558 T15629 T15631 det the,time
R10559 T15630 T15631 amod same,time
R10560 T15631 T15628 pobj time,at
R10561 T15632 T15633 expl there,was
R10562 T15633 T15607 conj was,altered
R10563 T15634 T15636 det a,up-regulation
R10564 T15635 T15636 amod synergistic,up-regulation
R10565 T15649 T15650 amod GP-mediated,modulations
R10566 T15636 T15633 attr up-regulation,was
R10567 T15637 T15636 prep of,up-regulation
R10568 T15638 T15637 pobj IL-1RA,of
R10569 T15650 T15648 pobj modulations,by
R10570 T15639 T15633 punct .,was
R10571 T15640 T15647 prep In,caused
R10572 T15641 T15640 pobj part,In
R10573 T15642 T15647 punct ",",caused
R10574 T15651 T15650 prep of,modulations
R10575 T15643 T15644 det this,change
R10576 T15644 T15647 nsubjpass change,caused
R10577 T15652 T15655 det the,binding
R10578 T15645 T15647 aux may,caused
R10579 T15646 T15647 auxpass be,caused
R10580 T15647 T15647 ROOT caused,caused
R10581 T15653 T15654 advmod TSST-1,induced
R10582 T15654 T15655 advmod induced,binding
R10583 T15655 T15651 pobj binding,of
R10584 T15745 T15744 punct -,TSST-1
R10585 T15656 T15655 prep of,binding
R10586 T15746 T15744 cc and,TSST-1
R10587 T15747 T15748 amod LPS-induced,binding
R10588 T15657 T15656 pobj NFκB,of
R10589 T15748 T15744 conj binding,TSST-1
R10590 T15749 T15748 prep to,binding
R10591 T15750 T15751 det the,NFκB3
R10592 T15658 T15657 punct ",",NFκB
R10593 T15751 T15749 pobj NFκB3,to
R10594 T15752 T15751 cc and,NFκB3
R10595 T15753 T15755 det the,binding
R10596 T15659 T15657 conj NFIL-6,NFκB
R10597 T15754 T15755 amod TSST-1-induced,binding
R10598 T15755 T15744 conj binding,TSST-1
R10599 T15756 T15755 prep to,binding
R10600 T15757 T15761 det the,site
R10601 T15660 T15659 cc and,NFIL-6
R10602 T15758 T15761 amod new,site
R10603 T15759 T15761 compound NFκB,site
R10604 T15760 T15761 compound consensus,site
R10605 T15661 T15659 conj NFAT,NFIL-6
R10606 T15761 T15756 pobj site,to
R10607 T15762 T15734 conj seemed,examined
R10608 T15763 T15765 aux to,increased
R10609 T15662 T15663 aux to,known
R10610 T15764 T15765 auxpass be,increased
R10611 T15765 T15762 xcomp increased,seemed
R10612 T15766 T15765 prep by,increased
R10613 T15767 T15766 pobj GP,by
R10614 T15768 T15762 punct .,seemed
R10615 T15663 T15647 xcomp known,caused
R10616 T15769 T15794 advmod So,was
R10617 T15770 T15794 punct ",",was
R10618 T15771 T15773 mark while,observed
R10619 T15772 T15773 nsubj we,observed
R10620 T15664 T15663 cc and,known
R10621 T15773 T15794 advcl observed,was
R10622 T15774 T15776 det a,down-regulation
R10623 T15775 T15776 amod GP-mediated,down-regulation
R10624 T15665 T15686 nmod up,promoter
R10625 T15776 T15773 dobj down-regulation,observed
R10626 T15777 T15776 prep of,down-regulation
R10627 T15778 T15779 det the,LPS
R10628 T15666 T15665 prep to,up
R10629 T15779 T15777 pobj LPS,of
R10630 T15780 T15776 punct -,down-regulation
R10631 T15781 T15776 cc and,down-regulation
R10632 T15667 T15666 pcomp now,to
R10633 T15782 T15784 det the,NFκB
R10634 T15783 T15784 amod TSST-1-induced,NFκB
R10635 T15784 T15785 nsubj NFκB,binding
R10636 T15668 T15669 amod unknown,sites
R10637 T15785 T15776 conj binding,down-regulation
R10638 T15786 T15785 prep to,binding
R10639 T15787 T15786 pobj sites,to
R10640 T15669 T15666 pobj sites,to
R10641 T15788 T15787 prep of,sites
R10642 T15789 T15791 det the,promoter
R10643 T15670 T15669 prep within,sites
R10644 T15790 T15791 compound TNFα,promoter
R10645 T15791 T15788 pobj promoter,of
R10646 T15792 T15794 punct ",",was
R10647 T15671 T15672 det the,IL-8
R10648 T15793 T15794 expl there,was
R10649 T15794 T15794 ROOT was,was
R10650 T15795 T15796 det an,up-regulation
R10651 T15672 T15670 pobj IL-8,within
R10652 T15796 T15794 attr up-regulation,was
R10653 T15797 T15796 prep to,up-regulation
R10654 T15798 T15802 nmod NFκB3,sites
R10655 T15673 T15672 cc and,IL-8
R10656 T15799 T15798 cc and,NFκB3
R10657 T15800 T15798 conj NFκB,NFκB3
R10658 T15801 T15802 compound consensus,sites
R10659 T15674 T15675 compound IL-1RA,promoter
R10660 T15675 T15672 conj promoter,IL-8
R10661 T15802 T15797 pobj sites,to
R10662 T15803 T15802 prep of,sites
R10663 T15804 T15806 det the,promoter
R10664 T15805 T15806 compound IL-1RA,promoter
R10665 T15676 T15677 advmod instead,of
R10666 T15806 T15803 pobj promoter,of
R10667 T15807 T15794 punct .,was
R10668 T15808 T15811 det These,data
R10669 T15809 T15810 advmod seemingly,contradictory
R10670 T15677 T15669 cc of,sites
R10671 T15810 T15811 amod contradictory,data
R10672 T15811 T15814 nsubjpass data,explained
R10673 T15678 T15679 det the,TNFα
R10674 T15812 T15814 aux could,explained
R10675 T15813 T15814 auxpass be,explained
R10676 T15814 T15814 ROOT explained,explained
R10677 T15679 T15669 conj TNFα,sites
R10678 T15680 T15679 punct ",",TNFα
R10679 T15815 T15814 agent by,explained
R10680 T15816 T15815 pobj differences,by
R10681 T15681 T15679 conj IL-1β,TNFα
R10682 T15817 T15816 prep in,differences
R10683 T15818 T15820 preconj either,subunits
R10684 T15682 T15681 punct ",",IL-1β
R10685 T15819 T15820 compound NFκB,subunits
R10686 T15820 T15817 pobj subunits,in
R10687 T15821 T15816 cc or,differences
R10688 T15683 T15681 conj IL-6,IL-1β
R10689 T15822 T15823 amod conserved,nucleotides
R10690 T15823 T15816 conj nucleotides,differences
R10691 T15824 T15853 punct (,contains
R10692 T15684 T15683 cc or,IL-6
R10693 T15825 T15853 nsubj #,contains
R10694 T15826 T15825 nummod 1,#
R10695 T15827 T15832 punct ",",10
R10696 T15685 T15683 conj IFNγ,IL-6
R10697 T15828 T15832 dep 2,10
R10698 T15829 T15830 punct ",",3
R10699 T15830 T15828 prep 3,2
R10700 T15686 T15663 conj promoter,known
R10701 T15831 T15832 punct ",",10
R10702 T15832 T15825 appos 10,#
R10703 T15833 T15825 punct ),#
R10704 T15687 T15647 punct .,caused
R10705 T15834 T15825 prep within,#
R10706 T15835 T15839 det the,motif
R10707 T15836 T15839 amod decameric,motif
R10708 T15688 T15691 advmod Accordingly,found
R10709 T15837 T15839 amod NFκB,motif
R10710 T15838 T15839 amod binding,motif
R10711 T15689 T15691 punct ",",found
R10712 T15839 T15834 pobj motif,within
R10713 T15840 T15839 prep between,motif
R10714 T15841 T15842 det the,TNFα
R10715 T15690 T15691 nsubj we,found
R10716 T15691 T15720 ccomp found,p
R10717 T15842 T15840 pobj TNFα,between
R10718 T15843 T15842 cc and,TNFα
R10719 T15844 T15846 det the,promoter
R10720 T15692 T15705 mark that,correlated
R10721 T15845 T15846 compound IL-1RA,promoter
R10722 T15846 T15842 conj promoter,TNFα
R10723 T15847 T15846 punct (,promoter
R10724 T15693 T15695 det the,binding
R10725 T15848 T15846 prep for,promoter
R10726 T15849 T15848 pobj NFκB3,for
R10727 T15694 T15695 advmod TSST-1-induced,binding
R10728 T15850 T15852 det the,motif
R10729 T15851 T15852 compound IL-1RA,motif
R10730 T15695 T15705 nsubj binding,correlated
R10731 T15852 T15846 conj motif,promoter
R10732 T15853 T15814 parataxis contains,explained
R10733 T15854 T15855 det a,T
R10734 T15696 T15695 prep of,binding
R10735 T15855 T15853 dobj T,contains
R10736 T15856 T15855 prep on,T
R10737 T15857 T15856 pobj position,on
R10738 T15697 T15696 pobj NFκB,of
R10739 T15858 T15857 nummod 10,position
R10740 T15859 T15860 advmod instead,of
R10741 T15860 T15857 cc of,position
R10742 T15698 T15695 prep to,binding
R10743 T15861 T15863 det the,C
R10744 T15862 T15863 amod conserved,C
R10745 T15699 T15698 pobj sites,to
R10746 T15863 T15855 conj C,T
R10747 T15864 T15863 prep in,C
R10748 T15700 T15699 prep from,sites
R10749 T15865 T15867 det the,motif
R10750 T15866 T15867 compound TNFα,motif
R10751 T15701 T15703 det the,promoter
R10752 T15867 T15864 pobj motif,in
R10753 T15868 T15853 punct ",",contains
R10754 T15869 T15814 conj see,explained
R10755 T15702 T15703 compound TNFα,promoter
R10756 T15870 T15869 dobj Table,see
R10757 T15871 T15870 nummod 1,Table
R10758 T15872 T15869 punct ),see
R10759 T15703 T15700 pobj promoter,from
R10760 T15873 T15814 punct ",",explained
R10761 T15874 T15875 advmod probably,leading
R10762 T15875 T15814 advcl leading,explained
R10763 T15876 T15875 prep to,leading
R10764 T15877 T15876 pobj differences,to
R10765 T15878 T15877 prep in,differences
R10766 T15704 T15705 advmod negatively,correlated
R10767 T15879 T15882 amod binding,]
R10768 T15880 T15882 compound [,]
R10769 T15705 T15691 ccomp correlated,found
R10770 T15881 T15882 compound "41,42",]
R10771 T15882 T15878 pobj ],in
R10772 T15883 T15814 punct .,explained
R10773 T15706 T15705 prep with,correlated
R10774 T15884 T15916 prep Despite,observed
R10775 T15885 T15886 det the,location
R10776 T15886 T15884 pobj location,Despite
R10777 T15707 T15709 det the,enhancement
R10778 T15887 T15886 prep of,location
R10779 T15888 T15892 det the,site
R10780 T15889 T15892 amod new,site
R10781 T15708 T15709 amod GP-mediated,enhancement
R10782 T15890 T15892 compound NFκB,site
R10783 T15891 T15892 compound consensus,site
R10784 T15892 T15887 pobj site,of
R10785 T15709 T15706 pobj enhancement,with
R10786 T15893 T15892 punct (,site
R10787 T15710 T15709 prep of,enhancement
R10788 T15894 T15892 appos -266,site
R10789 T15711 T15714 det the,production
R10790 T15895 T15886 cc and,location
R10791 T15896 T15886 conj -280,location
R10792 T15712 T15714 amod TSST-1-induced,production
R10793 T15897 T15884 punct ),Despite
R10794 T15898 T15884 prep in,Despite
R10795 T15713 T15714 compound IL-1RA,production
R10796 T15899 T15901 det the,element
R10797 T15900 T15901 amod inhibitory,element
R10798 T15901 T15898 pobj element,in
R10799 T15714 T15710 pobj production,of
R10800 T15902 T15901 punct (,element
R10801 T15903 T15901 appos -250,element
R10802 T15715 T15718 punct (,-0.88
R10803 T15904 T15903 cc and,-250
R10804 T15905 T15903 conj -294,-250
R10805 T15716 T15718 dep r,-0.88
R10806 T15906 T15901 punct ),element
R10807 T15907 T15901 prep of,element
R10808 T15908 T15910 det the,promoter
R10809 T15717 T15718 punct =,-0.88
R10810 T15909 T15910 compound IL-1RA,promoter
R10811 T15910 T15907 pobj promoter,of
R10812 T15911 T15913 nmod [,]
R10813 T15912 T15913 nummod 30,]
R10814 T15913 T15910 appos ],promoter
R10815 T15914 T15916 punct ",",observed
R10816 T15718 T15709 appos -0.88,enhancement
R10817 T15915 T15916 nsubj we,observed
R10818 T15916 T15916 ROOT observed,observed
R10819 T15917 T15918 det no,inhibition
R10820 T15918 T15916 dobj inhibition,observed
R10821 T15719 T15720 punct ;,p
R10822 T15919 T15916 punct .,observed
R10823 T15920 T15926 prep On,found
R10824 T15720 T15720 ROOT p,p
R10825 T15921 T15923 det the,side
R10826 T15922 T15923 amod other,side
R10827 T15923 T15920 pobj side,On
R10828 T15721 T15722 compound <,0.01
R10829 T15924 T15926 punct ",",found
R10830 T15925 T15926 nsubj we,found
R10831 T15926 T15926 ROOT found,found
R10832 T15927 T15932 det an,site
R10833 T15722 T15720 nummod 0.01,p
R10834 T15928 T15932 amod inhibitory,site
R10835 T15929 T15930 compound NFκB2,/
R10836 T15723 T15720 punct ;,p
R10837 T15930 T15932 nmod /,site
R10838 T15931 T15930 nummod 3,/
R10839 T15932 T15926 dobj site,found
R10840 T15724 T15720 conj data,p
R10841 T15933 T15932 punct (,site
R10842 T15934 T15932 appos -288,site
R10843 T15935 T15932 cc and,site
R10844 T15725 T15726 neg not,shown
R10845 T15936 T15932 conj -302,site
R10846 T15937 T15932 punct ),site
R10847 T15938 T15926 prep towards,found
R10848 T15726 T15724 acl shown,data
R10849 T15727 T15726 prep in,shown
R10850 T15728 T15727 pobj detail,in
R10851 T15939 T15940 det the,end
R10852 T15729 T15724 punct ),data
R10853 T15940 T15938 pobj end,towards
R10854 T15941 T15940 prep of,end
R10855 T15730 T15720 punct .,p
R10856 T15942 T15944 det the,element
R10857 T15943 T15944 amod inhibitory,element
R10858 T15731 T15734 prep Of,examined
R10859 T15944 T15941 pobj element,of
R10860 T15945 T15926 punct ",",found
R10861 T15946 T15926 advcl demonstrating,found
R10862 T15732 T15733 det the,four
R10863 T15947 T15946 dobj down-regulations,demonstrating
R10864 T15948 T15947 prep of,down-regulations
R10865 T15949 T15950 det the,LPS
R10866 T15950 T15948 pobj LPS,of
R10867 T15951 T15947 punct -,down-regulations
R10868 T15952 T15947 cc and,down-regulations
R10869 T15953 T15954 compound TSST-1-induced,binding
R10870 T15733 T15734 nsubj four,examined
R10871 T15954 T15947 conj binding,down-regulations
R10872 T15955 T15947 punct ",",down-regulations
R10873 T15956 T15960 nsubjpass which,altered
R10874 T15734 T15734 ROOT examined,examined
R10875 T15957 T15960 aux could,altered
R10876 T15958 T15960 neg not,altered
R10877 T15735 T15736 compound NFκB,sites
R10878 T15959 T15960 auxpass be,altered
R10879 T15960 T15947 relcl altered,down-regulations
R10880 T15961 T15960 agent by,altered
R10881 T15736 T15734 dobj sites,examined
R10882 T15962 T15961 pobj GP,by
R10883 T15963 T15926 punct .,found
R10884 T15964 T15972 prep In,represent
R10885 T15965 T15966 poss our,opinion
R10886 T15737 T15734 prep from,examined
R10887 T15966 T15964 pobj opinion,In
R10888 T15967 T15972 punct ",",represent
R10889 T15968 T15969 det this,site
R10890 T15738 T15740 det the,promoter
R10891 T15969 T15972 nsubj site,represent
R10892 T15970 T15972 aux may,represent
R10893 T15971 T15972 advmod therefore,represent
R10894 T15739 T15740 compound IL-1RA,promoter
R10895 T15972 T15972 ROOT represent,represent
R10896 T15740 T15737 pobj promoter,from
R10897 T15973 T15974 advmod at,least
R10898 T15741 T15734 punct ",",examined
R10899 T15974 T15976 advmod least,part
R10900 T15975 T15976 det a,part
R10901 T15976 T15972 dobj part,represent
R10902 T15742 T15744 advmod mostly,TSST-1
R10903 T15977 T15976 prep of,part
R10904 T15978 T15982 det the,element
R10905 T15743 T15744 det the,TSST-1
R10906 T15979 T15982 amod previoulsy,element
R10907 T15980 T15982 amod described,element
R10908 T15981 T15982 compound inhibitory,element
R10909 T15744 T15762 nsubj TSST-1,seemed
R10910 T15982 T15977 pobj element,of
R10911 T15983 T15985 nmod [,]
R10912 T16036 T16028 ccomp reflected,think
R10913 T15984 T15985 nummod 30,]
R10914 T15985 T15982 appos ],element
R10915 T15986 T15972 punct .,represent
R10916 T15987 T15989 det The,increase
R10917 T15988 T15989 amod GP-modulated,increase
R10918 T15989 T15992 nsubj increase,binding
R10919 T15990 T15989 prep in,increase
R10920 T15991 T15992 amod TSST-1-induced,binding
R10921 T15992 T16017 csubj binding,explain
R10922 T15993 T15992 prep to,binding
R10923 T15994 T15996 det the,NFκB3
R10924 T16037 T16036 agent by,reflected
R10925 T15995 T15996 amod new,NFκB3
R10926 T15996 T15993 pobj NFκB3,to
R10927 T15997 T15996 cc and,NFκB3
R10928 T16038 T16039 det the,decrease
R10929 T15998 T16000 compound NFκB,site
R10930 T15999 T16000 compound consensus,site
R10931 T16000 T15996 conj site,NFκB3
R10932 T16039 T16037 pobj decrease,by
R10933 T16001 T16000 punct ",",site
R10934 T16002 T16004 det the,site
R10935 T16003 T16004 compound NFIL-6,site
R10936 T16040 T16039 prep of,decrease
R10937 T16004 T15992 dobj site,binding
R10938 T16005 T16004 appos [,site
R10939 T16006 T16007 nummod 32,]
R10940 T16041 T16045 det the,ratio
R10941 T16007 T16004 npadvmod ],site
R10942 T16008 T16010 advmod as,as
R10943 T16009 T16010 advmod well,as
R10944 T16042 T16045 amod IL-1β,ratio
R10945 T16010 T16004 cc as,site
R10946 T16011 T15992 prep to,binding
R10947 T16012 T16015 det the,site
R10948 T16043 T16045 nmod /,ratio
R10949 T16013 T16015 compound novel,site
R10950 T16014 T16015 compound NFATP2/3,site
R10951 T16015 T16011 pobj site,to
R10952 T16044 T16045 compound IL-1RA,ratio
R10953 T16016 T16017 aux may,explain
R10954 T16017 T16017 ROOT explain,explain
R10955 T16018 T16020 det the,up-regulation
R10956 T16045 T16040 pobj ratio,of
R10957 T16019 T16020 amod synergistic,up-regulation
R10958 T16020 T16017 dobj up-regulation,explain
R10959 T16021 T16020 prep of,up-regulation
R10960 T16046 T16045 acl following,ratio
R10961 T16022 T16025 det the,production
R10962 T16023 T16025 amod TSST-1-induced,production
R10963 T16024 T16025 compound IL-1RA,production
R10964 T16025 T16021 pobj production,of
R10965 T16026 T16017 punct .,explain
R10966 T16027 T16028 nsubj We,think
R10967 T16047 T16049 compound GP,TSST-1
R10968 T16028 T16028 ROOT think,think
R10969 T16029 T16036 mark that,reflected
R10970 T16030 T16032 det this,activation
R10971 T16031 T16032 amod GP-modulated,activation
R10972 T16048 T16049 compound +,TSST-1
R10973 T16032 T16036 nsubjpass activation,reflected
R10974 T16033 T16032 prep of,activation
R10975 T16034 T16033 pobj transcription,of
R10976 T16049 T16046 dobj TSST-1,following
R10977 T16035 T16036 auxpass was,reflected
R10978 T16050 T16049 punct (,TSST-1
R10979 T16051 T16049 appos Fig.,TSST-1
R10980 T16052 T16051 nummod 6,Fig.
R10982 T16053 T16049 punct ),TSST-1
R10983 T16134 T16132 appos data,cells
R10984 T16135 T16136 neg not,shown
R10985 T16054 T16028 punct .,think
R10986 T16136 T16134 acl shown,data
R10987 T16137 T16136 prep in,shown
R10988 T16138 T16137 pobj detail,in
R10989 T16055 T16062 prep In,postulated
R10990 T16139 T16134 punct ),data
R10991 T16140 T16122 punct .,reduced
R10992 T16056 T16057 det this,context
R10993 T16141 T16144 det The,effects
R10994 T16142 T16144 amod weaker,effects
R10995 T16143 T16144 amod modulating,effects
R10996 T16144 T16152 nsubj effects,observed
R10997 T16057 T16055 pobj context,In
R10998 T16145 T16144 prep of,effects
R10999 T16146 T16145 pobj GP,of
R11000 T16058 T16062 punct ",",postulated
R11001 T16147 T16144 prep on,effects
R11002 T16148 T16151 det the,response
R11003 T16149 T16151 amod LPS-induced,response
R11004 T16150 T16151 amod immune,response
R11005 T16059 T16062 nsubjpass it,postulated
R11006 T16151 T16147 pobj response,on
R11007 T16152 T16152 ROOT observed,observed
R11008 T16060 T16062 aux has,postulated
R11009 T16153 T16152 prep in,observed
R11010 T16154 T16155 det this,study
R11011 T16155 T16153 pobj study,in
R11012 T16061 T16062 auxpass been,postulated
R11013 T16156 T16159 punct ",",attributed
R11014 T16157 T16159 aux may,attributed
R11015 T16158 T16159 auxpass be,attributed
R11016 T16159 T16152 ccomp attributed,observed
R11017 T16160 T16159 prep to,attributed
R11018 T16161 T16162 advmod delicately,balanced
R11019 T16062 T16062 ROOT postulated,postulated
R11020 T16162 T16163 amod balanced,differences
R11021 T16163 T16160 pobj differences,to
R11022 T16164 T16163 prep in,differences
R11023 T16165 T16164 pcomp signaling,in
R11024 T16063 T16074 mark that,control
R11025 T16166 T16165 dobj pathways,signaling
R11026 T16167 T16166 prep between,pathways
R11027 T16064 T16074 prep in,control
R11028 T16065 T16064 pobj vitro,in
R11029 T16168 T16167 pobj LPS,between
R11030 T16066 T16068 det a,excess
R11031 T16169 T16168 cc and,LPS
R11032 T16170 T16171 compound TSST-1,[
R11033 T16067 T16068 amod 100fold,excess
R11034 T16171 T16168 conj [,LPS
R11035 T16172 T16173 compound 43-45,]
R11036 T16173 T16168 conj ],LPS
R11037 T16068 T16074 nsubj excess,control
R11038 T16174 T16152 punct .,observed
R11039 T16175 T16178 nsubjpass TSST-1,shown
R11040 T16176 T16178 aux has,shown
R11041 T16069 T16068 prep of,excess
R11042 T16177 T16178 auxpass been,shown
R11043 T16178 T16178 ROOT shown,shown
R11044 T16179 T16180 aux to,use
R11045 T16180 T16178 xcomp use,shown
R11046 T16070 T16069 pobj IL-1RA,of
R11047 T16181 T16183 det the,pathway
R11048 T16182 T16183 compound PI3K,pathway
R11049 T16183 T16180 dobj pathway,use
R11050 T16071 T16068 prep over,excess
R11051 T16184 T16180 prep for,use
R11052 T16185 T16184 pcomp signaling,for
R11053 T16186 T16185 dobj [,signaling
R11054 T16072 T16071 pobj IL-1β,over
R11055 T16187 T16188 nummod 44,]
R11056 T16188 T16185 dobj ],signaling
R11057 T16189 T16188 cc and,]
R11058 T16073 T16074 aux might,control
R11059 T16190 T16191 det this,effect
R11060 T16191 T16188 conj effect,]
R11061 T16192 T16194 aux may,sustained
R11062 T16074 T16062 ccomp control,postulated
R11063 T16193 T16194 auxpass be,sustained
R11064 T16194 T16178 conj sustained,shown
R11065 T16195 T16194 agent by,sustained
R11066 T16196 T16197 compound GP,treatment
R11067 T16197 T16200 compound treatment,]
R11068 T16198 T16200 compound [,]
R11069 T16075 T16077 det the,effects
R11070 T16199 T16200 compound "22,37",]
R11071 T16200 T16195 pobj ],by
R11072 T16201 T16178 punct .,shown
R11073 T16076 T16077 amod biological,effects
R11074 T16202 T16205 nsubjpass It,demonstrated
R11075 T16203 T16205 aux has,demonstrated
R11076 T16204 T16205 auxpass been,demonstrated
R11077 T16077 T16074 dobj effects,control
R11078 T16205 T16205 ROOT demonstrated,demonstrated
R11079 T16206 T16214 mark that,controls
R11080 T16207 T16214 prep in,controls
R11081 T16078 T16077 prep of,effects
R11082 T16079 T16080 compound IL-1,[
R11083 T16208 T16209 amod septic/LPS-adapted,leukocytes
R11084 T16209 T16207 pobj leukocytes,in
R11085 T16080 T16082 compound [,]
R11086 T16210 T16212 det the,pathway
R11087 T16211 T16212 compound PI3K,pathway
R11088 T16212 T16214 nsubj pathway,controls
R11089 T16081 T16082 compound "46,47",]
R11090 T16213 T16214 advmod selectively,controls
R11091 T16214 T16205 ccomp controls,demonstrated
R11092 T16215 T16214 dobj sIL-1RA,controls
R11093 T16082 T16078 pobj ],of
R11094 T16216 T16215 cc but,sIL-1RA
R11095 T16217 T16218 neg not,IL-1β
R11096 T16083 T16062 punct .,postulated
R11097 T16218 T16219 amod IL-1β,production
R11098 T16219 T16220 compound production,[
R11099 T16220 T16215 conj [,sIL-1RA
R11100 T16084 T16098 mark Since,is
R11101 T16221 T16222 nummod 48,]
R11102 T16222 T16215 conj ],sIL-1RA
R11103 T16223 T16205 punct .,demonstrated
R11104 T16085 T16098 punct ",",is
R11105 T16224 T16229 nsubjpass Signaling,reported
R11106 T16225 T16224 prep via,Signaling
R11107 T16226 T16225 pobj PI3K,via
R11108 T16086 T16098 prep in,is
R11109 T16227 T16229 aux has,reported
R11110 T16228 T16229 auxpass been,reported
R11111 T16229 T16229 ROOT reported,reported
R11112 T16087 T16086 pobj fact,in
R11113 T16088 T16098 punct ",",is
R11114 T16230 T16232 aux to,involved
R11115 T16231 T16232 auxpass be,involved
R11116 T16232 T16229 xcomp involved,reported
R11117 T16089 T16093 det the,ratio
R11118 T16233 T16232 prep in,involved
R11119 T16234 T16235 det the,activation
R11120 T16235 T16233 pobj activation,in
R11121 T16090 T16093 amod IL-1β,ratio
R11122 T16236 T16235 prep of,activation
R11123 T16237 T16236 pobj NFAT,of
R11124 T16091 T16093 nmod /,ratio
R11125 T16238 T16235 prep in,activation
R11126 T16239 T16240 compound T,cells
R11127 T16240 T16238 pobj cells,in
R11128 T16092 T16093 compound IL-1RA,ratio
R11129 T16241 T16243 nmod [,]
R11130 T16242 T16243 nummod 49,]
R11131 T16243 T16235 appos ],activation
R11132 T16093 T16098 nsubj ratio,is
R11133 T16244 T16229 punct .,reported
R11134 T16245 T16250 nsubj Activation,take
R11135 T16246 T16245 prep of,Activation
R11136 T16094 T16093 acl following,ratio
R11137 T16247 T16246 pobj NFκB,of
R11138 T16248 T16250 aux can,take
R11139 T16249 T16250 advmod also,take
R11140 T16095 T16097 compound GP,TSST-1
R11141 T16250 T16250 ROOT take,take
R11142 T16251 T16250 dobj place,take
R11143 T16252 T16250 prep via,take
R11144 T16096 T16097 compound +,TSST-1
R11145 T16253 T16254 compound PI3K,[
R11146 T16254 T16256 nmod [,]
R11147 T16255 T16256 nummod 50,]
R11148 T16097 T16094 dobj TSST-1,following
R11149 T16256 T16252 pobj ],via
R11150 T16257 T16256 punct ",",]
R11151 T16258 T16260 nsubj which,offer
R11152 T16098 T16105 advcl is,is
R11153 T16259 T16260 aux may,offer
R11154 T16260 T16256 relcl offer,]
R11155 T16261 T16262 det an,explanation
R11156 T16099 T16102 advmod partially,0.01
R11157 T16262 T16260 dobj explanation,offer
R11158 T16263 T16262 prep for,explanation
R11159 T16264 T16265 det a,difference
R11160 T16100 T16102 amod less,0.01
R11161 T16265 T16263 pobj difference,for
R11162 T16266 T16265 prep in,difference
R11163 T16267 T16266 pcomp signaling,in
R11164 T16268 T16267 prep between,signaling
R11165 T16269 T16268 pobj GP,between
R11166 T16270 T16269 punct (,GP
R11167 T16101 T16102 quantmod than,0.01
R11168 T16271 T16269 appos PI3K,GP
R11169 T16272 T16269 punct ),GP
R11170 T16273 T16269 cc and,GP
R11171 T16102 T16098 attr 0.01,is
R11172 T16274 T16269 conj LPS,GP
R11173 T16275 T16277 punct (,kinase
R11174 T16276 T16277 amod mitogen-activated,kinase
R11175 T16103 T16105 punct ",",is
R11176 T16277 T16269 appos kinase,GP
R11177 T16278 T16277 acl signaling,kinase
R11178 T16279 T16277 punct ),kinase
R11179 T16104 T16105 nsubj it,is
R11180 T16280 T16250 punct .,take
R11181 T16281 T16282 det This,idea
R11182 T16282 T16285 nsubjpass idea,supported
R11183 T16283 T16285 aux may,supported
R11184 T16105 T16105 ROOT is,is
R11185 T16284 T16285 auxpass be,supported
R11186 T16285 T16285 ROOT supported,supported
R11187 T16106 T16105 neg not,is
R11188 T16286 T16285 agent by,supported
R11189 T16107 T16105 acomp unreasonable,is
R11190 T16287 T16288 det another,study
R11191 T16288 T16286 pobj study,by
R11192 T16108 T16109 aux to,assume
R11193 T16289 T16288 acl showing,study
R11194 T16290 T16289 dobj that,showing
R11195 T16291 T16289 prep despite,showing
R11196 T16109 T16105 xcomp assume,is
R11197 T16292 T16293 det the,use
R11198 T16293 T16291 pobj use,despite
R11199 T16294 T16293 prep of,use
R11200 T16110 T16114 mark that,inactivated
R11201 T16295 T16296 amod similar,PRR
R11202 T16296 T16294 pobj PRR,of
R11203 T16111 T16112 amod IL-1β,bioactivity
R11204 T16297 T16296 punct ",",PRR
R11205 T16298 T16296 conj LPS,PRR
R11206 T16299 T16298 cc and,LPS
R11207 T16112 T16114 nsubjpass bioactivity,inactivated
R11208 T16300 T16298 conj peptidoglycan,LPS
R11209 T16301 T16293 prep activated,use
R11210 T16302 T16304 det the,gene
R11211 T16113 T16114 auxpass is,inactivated
R11212 T16303 T16304 compound IL-1RA,gene
R11213 T16304 T16301 dobj gene,activated
R11214 T16305 T16301 prep through,activated
R11215 T16306 T16308 amod different,proteins
R11216 T16307 T16308 amod mechanisms/DNA-binding,proteins
R11217 T16308 T16305 pobj proteins,through
R11218 T16114 T16109 ccomp inactivated,assume
R11219 T16309 T16301 cc and,activated
R11220 T16310 T16301 conj acted,activated
R11221 T16311 T16310 advmod synergistically,acted
R11222 T16115 T16114 prep in,inactivated
R11223 T16312 T16310 prep in,acted
R11224 T16313 T16312 pobj combination,in
R11225 T16314 T16310 punct ",",acted
R11226 T16116 T16117 poss our,system
R11227 T16315 T16310 advcl suggestive,acted
R11228 T16316 T16315 prep of,suggestive
R11229 T16317 T16316 pobj signals,of
R11230 T16117 T16115 pobj system,in
R11231 T16318 T16319 nsubj which,are
R11232 T16319 T16317 relcl are,signals
R11233 T16320 T16319 neg not,are
R11234 T16118 T16105 punct .,is
R11235 T16321 T16319 acomp equivalent,are
R11236 T16322 T16321 prep in,equivalent
R11237 T16323 T16324 det all,parts
R11238 T16119 T16122 advmod Indeed,reduced
R11239 T16324 T16322 pobj parts,in
R11240 T16325 T16327 nmod [,]
R11241 T16326 T16327 nummod 51,]
R11242 T16120 T16122 punct ",",reduced
R11243 T16121 T16122 nsubj GP,reduced
R11244 T16327 T16315 dep ],suggestive
R11245 T16328 T16285 punct .,supported
R11246 T16122 T16122 ROOT reduced,reduced
R11247 T16123 T16128 det the,production
R11248 T16124 T16128 amod TSST-1-induced,production
R11249 T16125 T16128 punct ",",production
R11250 T16126 T16128 amod IL-1-dependent,production
R11251 T16127 T16128 compound IL-2,production
R11252 T16128 T16122 dobj production,reduced
R11256 T16129 T16128 prep of,production
R11260 T16130 T16132 nmod murine,cells
R11262 T16131 T16132 compound EL-4,cells
R11263 T16132 T16129 pobj cells,of
R11635 T17296 T17301 prep In,demonstrated
R11636 T17297 T17296 pobj summary,In
R11637 T17298 T17301 punct ",",demonstrated
R11638 T17299 T17300 poss our,data
R11639 T17300 T17301 nsubj data,demonstrated
R11640 T17301 T17301 ROOT demonstrated,demonstrated
R11641 T17302 T17307 mark that,induced
R11642 T17303 T17307 prep in,induced
R11643 T17304 T17306 amod vitro,phosphate
R11644 T17305 T17306 compound glucan,phosphate
R11645 T17306 T17303 pobj phosphate,in
R11646 T17307 T17301 ccomp induced,demonstrated
R11647 T17308 T17310 det a,factor
R11648 T17309 T17310 compound transcription,factor
R11649 T17310 T17307 dobj factor,induced
R11650 T17311 T17307 advmod binding,induced
R11651 T17312 T17307 cc and,induced
R11652 T17313 T17316 det a,profile
R11653 T17314 T17316 amod subsequent,profile
R11654 T17315 T17316 compound cytokine,profile
R11655 T17316 T17307 conj profile,induced
R11656 T17317 T17316 amod different,profile
R11657 T17318 T17317 prep from,different
R11658 T17319 T17318 pobj LPS,from
R11659 T17320 T17307 cc and,induced
R11660 T17321 T17322 advmod also,from
R11661 T17322 T17307 conj from,induced
R11662 T17323 T17322 pobj TSST-1,from
R11663 T17324 T17323 cc and,TSST-1
R11664 T17325 T17307 punct ",",induced
R11665 T17326 T17328 advmod moreover,switched
R11666 T17327 T17328 punct ",",switched
R11667 T17328 T17301 conj switched,demonstrated
R11668 T17329 T17332 det a,response
R11669 T17330 T17332 amod pro-inflammatory,response
R11670 T17331 T17332 amod TSST-1-induced,response
R11671 T17332 T17328 dobj response,switched
R11672 T17333 T17332 prep to,response
R11673 T17334 T17337 det an,reaction
R11674 T17335 T17337 amod IL-1RA-mediated,reaction
R11675 T17336 T17337 amod anti-inflammatory,reaction
R11676 T17337 T17333 pobj reaction,to
R11677 T17338 T17328 punct .,switched
R11678 T17339 T17340 poss Our,results
R11679 T17340 T17342 nsubj results,generated
R11680 T17341 T17342 advmod also,generated
R11681 T17342 T17342 ROOT generated,generated
R11682 T17343 T17344 amod new,insights
R11683 T17344 T17342 dobj insights,generated
R11684 T17345 T17344 prep into,insights
R11685 T17346 T17349 det a,interplay
R11686 T17347 T17348 advmod very,complex
R11687 T17348 T17349 amod complex,interplay
R11688 T17349 T17345 pobj interplay,into
R11689 T17350 T17349 prep of,interplay
R11690 T17351 T17352 compound transcription,factor
R11691 T17352 T17350 pobj factor,of
R11692 T17353 T17349 amod binding,interplay
R11693 T17354 T17353 prep to,binding
R11694 T17355 T17360 amod various,sites
R11695 T17356 T17360 amod known,sites
R11696 T17357 T17356 cc and,known
R11697 T17358 T17359 advmod newly,identified
R11698 T17359 T17356 conj identified,known
R11699 T17360 T17354 pobj sites,to
R11700 T17361 T17360 prep in,sites
R11701 T17362 T17364 det the,promoter
R11702 T17363 T17364 compound IL-1RA,promoter
R11703 T17364 T17361 pobj promoter,in
R11704 T17365 T17364 punct (,promoter
R11705 T17366 T17367 nmod Fig.,8
R11706 T17367 T17364 appos 8,promoter
R11707 T17368 T17364 punct ),promoter
R11708 T17369 T17360 punct ",",sites
R11709 T17370 T17373 nsubjpass which,regulated
R11710 T17371 T17373 aux can,regulated
R11711 T17372 T17373 auxpass be,regulated
R11712 T17373 T17360 relcl regulated,sites
R11713 T17374 T17373 advmod differentially,regulated
R11714 T17375 T17373 agent by,regulated
R11715 T17376 T17378 det a,carbohydrate
R11716 T17377 T17378 amod fungal,carbohydrate
R11717 T17378 T17375 pobj carbohydrate,by
R11718 T17379 T17342 punct .,generated
R11719 T17380 T17381 advmod Together,with
R11720 T17381 T17393 prep with,support
R11721 T17382 T17383 det the,in
R11722 T17383 T17381 pobj in,with
R11723 T17384 T17385 compound vivo,studies
R11724 T17385 T17383 pobj studies,in
R11725 T17386 T17388 compound [,]
R11726 T17387 T17388 compound "22,37",]
R11727 T17388 T17385 appos ],studies
R11728 T17389 T17393 punct ",",support
R11729 T17390 T17391 poss our,findings
R11730 T17391 T17393 nsubj findings,support
R11731 T17392 T17393 aux might,support
R11732 T17393 T17393 ROOT support,support
R11733 T17394 T17395 det the,concept
R11734 T17395 T17393 dobj concept,support
R11735 T17396 T17395 prep of,concept
R11736 T17397 T17398 amod protective,effects
R11737 T17398 T17396 pobj effects,of
R11738 T17399 T17395 acl mediated,concept
R11739 T17400 T17399 agent by,mediated
R11740 T17401 T17402 amod glucan,phosphate
R11741 T17402 T17400 pobj phosphate,by
R11742 T17403 T17402 prep in,phosphate
R11743 T17404 T17405 amod pro-inflammatory,conditions
R11744 T17405 T17403 pobj conditions,in
R11745 T17406 T17395 punct ",",concept
R11746 T17407 T17408 advmod especially,with
R11747 T17408 T17393 prep with,support
R11748 T17409 T17414 det a,ratio
R11749 T17410 T17414 amod dysregulated,ratio
R11750 T17411 T17414 nmod IL-1β,ratio
R11751 T17412 T17414 nmod /,ratio
R11752 T17413 T17414 compound IL-1RA,ratio
R11753 T17414 T17408 pobj ratio,with
R11754 T17415 T17417 nmod [,]
R11755 T17416 T17417 nummod "52,53",]
R11756 T17417 T17414 appos ],ratio
R11757 T17418 T17393 punct .,support
R11837 T17536 T17547 nsubjpass Materials,prepared
R11838 T17537 T17542 nmod Water,3-D-glucan
R11839 T17538 T17539 amod soluble,phosphorylated
R11840 T17539 T17542 amod phosphorylated,3-D-glucan
R11841 T17540 T17542 amod β-1,3-D-glucan
R11842 T17541 T17542 compound →,3-D-glucan
R11843 T17542 T17542 ROOT 3-D-glucan,3-D-glucan
R11844 T17543 T17544 punct (,GP
R11845 T17544 T17542 appos GP,3-D-glucan
R11846 T17545 T17542 punct ),3-D-glucan
R11847 T17546 T17547 auxpass was,prepared
R11848 T17547 T17547 ROOT prepared,prepared
R11849 T17548 T17549 mark as,done
R11850 T17549 T17547 advcl done,prepared
R11851 T17550 T17549 advmod before,done
R11852 T17551 T17553 nmod [,]
R11853 T17552 T17551 nummod 20,[
R11854 T17553 T17550 pobj ],before
R11876 T17575 T17574 punct ",",media
R11877 T17576 T17571 conj filter-sterilized,dissolved
R11878 T17577 T17579 punct (,μm
R11879 T17578 T17579 nummod 0.2,μm
R11880 T17579 T17576 appos μm,filter-sterilized
R11881 T17580 T17579 punct ),μm
R11882 T17581 T17576 cc and,filter-sterilized
R11883 T17582 T17576 conj screened,filter-sterilized
R11884 T17583 T17582 prep for,screened
R11885 T17584 T17585 compound endotoxin,contamination
R11886 T17585 T17583 pobj contamination,for
R11887 T17586 T17585 prep with,contamination
R11888 T17587 T17589 det the,assay
R11889 T17588 T17589 compound Endospecy,assay
R11890 T17589 T17586 pobj assay,with
R11891 T17590 T17589 punct (,assay
R11892 T17591 T17589 appos Seigakaku,assay
R11893 T17592 T17591 punct ",",Seigakaku
R11894 T17593 T17606 nsubj Tokyo,respond
R11895 T17594 T17593 punct ",",Tokyo
R11896 T17595 T17593 conj Japan,Tokyo
R11897 T17596 T17595 punct ),Japan
R11898 T17597 T17593 punct ",",Tokyo
R11899 T17598 T17599 nsubj which,is
R11900 T17599 T17593 relcl is,Tokyo
R11901 T17600 T17599 acomp specific,is
R11902 T17601 T17600 prep for,specific
R11903 T17602 T17601 pobj endotoxin,for
R11904 T17603 T17599 cc but,is
R11905 T17604 T17606 aux does,respond
R11906 T17605 T17606 neg not,respond
R11907 T17606 T17571 conj respond,dissolved
R11908 T17607 T17606 prep to,respond
R11909 T17608 T17610 amod β-1,3-D-glucans
R11910 T17609 T17610 compound →,3-D-glucans
R11911 T17610 T17607 pobj 3-D-glucans,to
R11912 T17611 T17606 punct .,respond
R12086 T17795 T17796 compound ethics,committee
R12087 T17796 T17793 pobj committee,of
R12088 T17797 T17796 prep of,committee
R12089 T17798 T17799 det the,University
R12090 T17799 T17797 pobj University,of
R12091 T17800 T17799 prep of,University
R12092 T17801 T17800 pobj Luebeck,of
R12093 T17802 T17778 punct .,obtained
R12094 T17803 T17805 det The,coats
R12095 T17804 T17805 amod buffy,coats
R12096 T17805 T17807 nsubjpass coats,separated
R12097 T17806 T17807 auxpass were,separated
R12098 T17807 T17807 ROOT separated,separated
R12099 T17808 T17807 prep over,separated
R12100 T17809 T17810 det a,Ficoll-Hypaque
R12101 T17810 T17808 pobj Ficoll-Hypaque,over
R12102 T17811 T17818 punct (,gradient
R12103 T17812 T17818 nmod Biochrom,gradient
R12104 T17813 T17812 punct ",",Biochrom
R12105 T17814 T17812 conj Berlin,Biochrom
R12106 T17815 T17814 punct ",",Berlin
R12107 T17816 T17814 conj Germany,Berlin
R12108 T17817 T17818 punct ),gradient
R12145 T17854 T17856 nummod ×,cells/ml
R12146 T17855 T17856 nummod 106,cells/ml
R12147 T17856 T17845 conj cells/ml,×
R12148 T17857 T17858 punct (,for
R12149 T17858 T17856 prep for,cells/ml
R12150 T17859 T17860 compound flow,cytometry
R12151 T17860 T17858 pobj cytometry,for
R12182 T17891 T17890 punct ",",Karlsruhe
R12183 T17892 T17890 conj Germany,Karlsruhe
R12184 T17893 T17890 punct ),Karlsruhe
R12185 T17894 T17888 punct ",",Invitrogen
R12186 T17895 T17896 nummod 1,%
R12187 T17896 T17897 compound %,penicillin
R12188 T17897 T17888 appos penicillin,Invitrogen
R12189 T17898 T17900 punct (,U/ml
R12190 T17899 T17900 nummod 10000,U/ml
R12191 T17900 T17897 appos U/ml,penicillin
R12192 T17901 T17900 punct ),U/ml
R12193 T17902 T17897 punct ",",penicillin
R12194 T17903 T17904 nummod 1,%
R12195 T17904 T17905 compound %,streptomycin
R12196 T17905 T17882 appos streptomycin,serum
R12197 T17906 T17905 punct (,streptomycin
R12198 T17907 T17910 nummod 10000,ml
R12199 T17908 T17910 compound μg,ml
R12200 T17909 T17910 compound /,ml
R12201 T17910 T17905 appos ml,streptomycin
R12202 T17911 T17905 punct ),streptomycin
R12203 T17912 T17905 punct ",",streptomycin
R12204 T17913 T17882 cc and,serum
R12205 T17914 T17915 nummod 1,%
R12206 T17915 T17876 npadvmod %,containing
R12207 T17916 T17918 nummod 200,L-glutamine
R12208 T17917 T17918 compound mM,L-glutamine
R12209 T17918 T17918 ROOT L-glutamine,L-glutamine
R12210 T17919 T17920 punct (,BioWhittaker
R12211 T17920 T17918 appos BioWhittaker,L-glutamine
R12212 T17921 T17918 punct ),L-glutamine
R12213 T17922 T17828 punct .,cultured
R12338 T18086 T18087 compound Stimulation,conditions
R12339 T18087 T18098 nsubjpass conditions,cultured
R12340 T18088 T18098 prep For,cultured
R12341 T18089 T18088 pobj induction,For
R12342 T18090 T18089 prep of,induction
R12343 T18091 T18092 compound transcription,factors
R12344 T18092 T18090 pobj factors,of
R12345 T18093 T18092 cc and,factors
R12346 T18094 T18092 conj cytokines,factors
R12347 T18095 T18098 punct ",",cultured
R12348 T18096 T18098 nsubjpass PBMC,cultured
R12349 T18097 T18098 auxpass were,cultured
R12350 T18098 T18098 ROOT cultured,cultured
R12351 T18099 T18098 prep in,cultured
R12352 T18100 T18101 det a,volume
R12353 T18101 T18099 pobj volume,in
R12354 T18102 T18101 prep of,volume
R12355 T18103 T18104 nummod 4,ml
R12356 T18104 T18102 pobj ml,of
R12357 T18105 T18101 prep in,volume
R12358 T18106 T18110 amod sterile,plates
R12359 T18107 T18110 amod pyrogen-free,plates
R12360 T18108 T18110 amod 6-well,plates
R12361 T18109 T18110 compound culture,plates
R12362 T18110 T18105 pobj plates,in
R12363 T18111 T18117 punct (,)
R12364 T18112 T18117 nmod Falcon,)
R12365 T18113 T18112 punct ",",Falcon
R12366 T18114 T18112 conj Heidelberg,Falcon
R12367 T18115 T18114 punct ",",Heidelberg
R12368 T18116 T18112 conj Germany,Falcon
R12369 T18117 T18098 punct ),cultured
R12370 T18118 T18098 punct .,cultured
R12371 T18119 T18121 nsubjpass Cultures,stimulated
R12372 T18120 T18121 auxpass were,stimulated
R12373 T18121 T18121 ROOT stimulated,stimulated
R12374 T18122 T18121 prep for,stimulated
R12375 T18123 T18124 nummod 1,h
R12376 T18124 T18122 pobj h,for
R12377 T18125 T18124 punct (,h
R12378 T18126 T18124 appos EMSA,h
R12379 T18127 T18126 punct ),EMSA
R12380 T18128 T18122 cc or,for
R12381 T18129 T18121 prep from,stimulated
R12382 T18130 T18133 quantmod 0,48
R12383 T18131 T18133 quantmod h,48
R12384 T18132 T18133 quantmod to,48
R12385 T18133 T18134 nummod 48,h
R12386 T18134 T18129 pobj h,from
R12387 T18135 T18134 punct (,h
R12388 T18136 T18134 appos ELISA,h
R12389 T18137 T18134 punct ),h
R12390 T18138 T18121 prep with,stimulated
R12391 T18139 T18142 nummod 1,μg
R12392 T18140 T18139 cc or,1
R12393 T18141 T18139 conj 100,1
R12394 T18142 T18138 pobj μg,with
R12395 T18143 T18142 prep per,μg
R12396 T18144 T18145 nummod 106,cells
R12397 T18145 T18143 pobj cells,per
R12398 T18146 T18145 prep of,cells
R12399 T18147 T18146 pobj GP,of
R12400 T18148 T18121 punct ",",stimulated
R12401 T18149 T18121 prep with,stimulated
R12402 T18150 T18152 nummod 250,cells
R12403 T18151 T18152 nummod ng/106,cells
R12404 T18152 T18149 pobj cells,with
R12405 T18153 T18173 nmod TSST-1,coli
R12406 T18154 T18156 punct (,Technologies
R12407 T18155 T18156 compound Toxin,Technologies
R12408 T18156 T18153 appos Technologies,TSST-1
R12409 T18157 T18156 punct ",",Technologies
R12410 T18158 T18156 conj Sarasota,Technologies
R12411 T18159 T18158 punct ",",Sarasota
R12412 T18160 T18158 conj FL,Sarasota
R12413 T18161 T18160 punct ",",FL
R12414 T18162 T18160 npadvmod USA,FL
R12415 T18163 T18160 punct ),FL
R12416 T18164 T18156 cc or,Technologies
R12417 T18165 T18153 prep with,TSST-1
R12418 T18166 T18168 nummod 250,cells
R12419 T18167 T18168 nummod ng/106,cells
R12420 T18168 T18165 pobj cells,with
R12421 T18169 T18170 compound wild-type,LPS
R12422 T18170 T18153 conj LPS,TSST-1
R12423 T18171 T18153 prep from,TSST-1
R12424 T18172 T18173 compound Escherichia,coli
R12425 T18173 T18174 nsubj coli,serotype
R12426 T18174 T18121 advcl serotype,stimulated
R12427 T18175 T18174 nummod 0111,serotype
R12428 T18176 T18174 punct :,serotype
R12429 T18177 T18179 nmod B4,Sigma
R12430 T18178 T18179 punct (,Sigma
R12431 T18179 T18174 appos Sigma,serotype
R12432 T18180 T18179 punct ",",Sigma
R12433 T18181 T18179 conj Munich,Sigma
R12434 T18182 T18181 punct ",",Munich
R12435 T18183 T18181 conj Germany,Munich
R12436 T18184 T18179 punct ),Sigma
R12437 T18185 T18121 punct .,stimulated
R12438 T18186 T18192 prep In,supplemented
R12439 T18187 T18188 amod costimulatory,experiments
R12440 T18188 T18186 pobj experiments,In
R12441 T18189 T18192 punct ",",supplemented
R12442 T18190 T18192 nsubjpass PBMC,supplemented
R12443 T18191 T18192 auxpass were,supplemented
R12444 T18192 T18192 ROOT supplemented,supplemented
R12445 T18193 T18192 advmod simultaneously,supplemented
R12446 T18194 T18192 prep with,supplemented
R12447 T18195 T18196 det a,combination
R12448 T18196 T18194 pobj combination,with
R12449 T18197 T18196 prep of,combination
R12450 T18198 T18197 pobj GP,of
R12451 T18199 T18198 cc and,GP
R12452 T18200 T18198 conj TSST-1,GP
R12453 T18201 T18194 cc or,with
R12454 T18202 T18194 conj with,with
R12455 T18203 T18204 det a,combination
R12456 T18204 T18202 pobj combination,with
R12457 T18205 T18204 prep of,combination
R12458 T18206 T18205 pobj GP,of
R12459 T18207 T18206 cc and,GP
R12460 T18208 T18206 conj LPS,GP
R12461 T18209 T18192 punct .,supplemented
R12666 T18530 T18530 ROOT Oligonucleotides,Oligonucleotides
R12667 T18531 T18532 punct (,Oligos
R12668 T18532 T18530 appos Oligos,Oligonucleotides
R12669 T18533 T18532 punct ),Oligos
R12670 T18534 T18530 cc and,Oligonucleotides
R12671 T18535 T18539 nummod 5,P-Labeling
R12672 T18536 T18537 punct ',-32
R12673 T18537 T18539 punct -32,P-Labeling
R12674 T18538 T18539 punct -,P-Labeling
R12675 T18539 T18530 conj P-Labeling,Oligonucleotides
R12676 T18540 T18542 det The,double-stranded
R12677 T18541 T18542 amod complementary,double-stranded
R12678 T18542 T18615 nsubj double-stranded,according
R12679 T18543 T18544 punct (,ds
R12680 T18544 T18561 nsubjpass ds,synthesised
R12681 T18545 T18544 punct ),ds
R12682 T18546 T18544 appos oligonucleotides,ds
R12683 T18547 T18548 punct (,oligos
R12684 T18548 T18546 appos oligos,oligonucleotides
R12685 T18549 T18546 punct ),oligonucleotides
R12686 T18550 T18544 prep from,ds
R12687 T18551 T18552 det the,TNFα
R12688 T18552 T18550 pobj TNFα,from
R12689 T18553 T18552 punct ",",TNFα
R12690 T18554 T18552 conj IL-8,TNFα
R12691 T18555 T18554 punct ",",IL-8
R12692 T18556 T18554 conj IFNγ,IL-8
R12693 T18557 T18556 cc and,IFNγ
R12694 T18558 T18556 conj IL-6,IFNγ
R12695 T18559 T18550 pobj promoters,from
R12696 T18560 T18561 auxpass were,synthesised
R12697 T18561 T18542 relcl synthesised,double-stranded
R12698 T18562 T18561 prep from,synthesised
R12699 T18563 T18564 amod single,stranded
R12700 T18564 T18561 conj stranded,synthesised
R12701 T18565 T18566 punct (,ss
R12702 T18566 T18564 appos ss,stranded
R12703 T18567 T18566 punct ),ss
R12704 T18568 T18566 appos oligos,ss
R12705 T18569 T18570 punct (,illustrated
R12706 T18570 T18568 acl illustrated,oligos
R12707 T18571 T18570 prep in,illustrated
R12708 T18572 T18571 pobj Table,in
R12709 T18573 T18572 nummod 1,Table
R12710 T18574 T18566 punct ),ss
R12711 T18575 T18564 punct ",",stranded
R12712 T18576 T18561 punct (,synthesised
R12713 T18577 T18578 compound TIB,Molbiol
R12714 T18578 T18600 nsubj Molbiol,using
R12715 T18579 T18578 punct ",",Molbiol
R12716 T18580 T18578 conj Berlin,Molbiol
R12717 T18581 T18580 punct ",",Berlin
R12718 T18582 T18580 conj Germany,Berlin
R12719 T18583 T18582 punct ),Germany
R12720 T18584 T18578 cc and,Molbiol
R12721 T18585 T18578 conj 32P-labeled,Molbiol
R12722 T18586 T18585 prep with,32P-labeled
R12723 T18587 T18589 nummod 5,γ-P-ATP
R12724 T18588 T18589 punct ',γ-P-ATP
R12725 T18589 T18586 pobj γ-P-ATP,with
R12726 T18590 T18592 punct (,Ci/mmol
R12727 T18591 T18592 nummod "3,000",Ci/mmol
R12728 T18592 T18589 appos Ci/mmol,γ-P-ATP
R12729 T18593 T18592 punct ",",Ci/mmol
R12730 T18594 T18592 conj Amersham,Ci/mmol
R12731 T18595 T18594 punct ",",Amersham
R12732 T18596 T18594 conj Braunschweig,Amersham
R12733 T18597 T18596 punct ",",Braunschweig
R12734 T18598 T18596 conj Germany,Braunschweig
R12735 T18599 T18589 punct ),γ-P-ATP
R12736 T18600 T18561 advcl using,synthesised
R12737 T18601 T18603 det the,Kit
R12738 T18602 T18603 compound Ready-To-Go-Polynucleotide-Kinase,Kit
R12739 T18603 T18600 dobj Kit,using
R12740 T18604 T18606 punct (,Kit
R12741 T18605 T18606 compound PNK,Kit
R12742 T18606 T18603 appos Kit,Kit
R12743 T18607 T18606 punct ",",Kit
R12744 T18608 T18609 compound Pharmacia,LKB
R12745 T18609 T18606 conj LKB,Kit
R12746 T18610 T18609 punct ",",LKB
R12747 T18611 T18609 conj Freiburg,LKB
R12748 T18612 T18611 punct ",",Freiburg
R12749 T18613 T18611 conj Germany,Freiburg
R12750 T18614 T18603 punct ),Kit
R12751 T18615 T18615 ROOT according,according
R12752 T18616 T18615 prep to,according
R12753 T18617 T18618 det the,manufacturer
R12754 T18618 T18620 poss manufacturer,instructions
R12755 T18619 T18618 case 's,manufacturer
R12756 T18620 T18616 pobj instructions,to
R12757 T18621 T18615 punct .,according
R12758 T18622 T18623 aux To,test
R12759 T18623 T18634 advcl test,used
R12760 T18624 T18626 det the,specificity
R12761 T18625 T18626 amod binding,specificity
R12762 T18626 T18623 dobj specificity,test
R12763 T18627 T18626 prep of,specificity
R12764 T18628 T18629 det the,oligos
R12765 T18629 T18627 pobj oligos,of
R12766 T18630 T18634 punct ",",used
R12767 T18631 T18632 amod mutated,oligos
R12768 T18632 T18634 nsubjpass oligos,used
R12769 T18633 T18634 auxpass were,used
R12770 T18634 T18634 ROOT used,used
R12771 T18635 T18634 prep as,used
R12772 T18636 T18638 det an,control
R12773 T18637 T18638 amod additional,control
R12774 T18638 T18635 pobj control,as
R12775 T18639 T18634 punct .,used
R12776 T18640 T18667 nsubjpass Mutations,reported
R12777 T18641 T18640 prep in,Mutations
R12778 T18642 T18644 det the,site
R12779 T18643 T18644 compound P2,site
R12780 T18644 T18641 pobj site,in
R12781 T18645 T18644 prep of,site
R12782 T18646 T18648 det the,promoter
R12783 T18647 T18648 compound IFNγ,promoter
R12784 T18648 T18645 pobj promoter,of
R12785 T18649 T18651 nmod [,]
R12786 T18650 T18651 nummod 29,]
R12787 T18651 T18648 appos ],promoter
R12788 T18652 T18641 cc and,in
R12789 T18653 T18641 conj in,in
R12790 T18654 T18657 det the,sequence
R12791 T18655 T18657 compound κ,sequence
R12792 T18656 T18657 compound consensus,sequence
R12793 T18657 T18653 pobj sequence,in
R12794 T18658 T18657 prep of,sequence
R12795 T18659 T18661 det the,promoter
R12796 T18660 T18661 compound TNFα,promoter
R12797 T18661 T18658 pobj promoter,of
R12798 T18662 T18664 nmod [,]
R12799 T18663 T18664 nummod 55,]
R12800 T18664 T18661 appos ],promoter
R12801 T18665 T18667 aux have,reported
R12802 T18666 T18667 auxpass been,reported
R12803 T18667 T18667 ROOT reported,reported
R12804 T18668 T18669 aux to,interfere
R12805 T18669 T18667 xcomp interfere,reported
R12806 T18670 T18669 prep with,interfere
R12807 T18671 T18670 pobj sequences,with
R12808 T18672 T18671 punct ",",sequences
R12809 T18673 T18674 nsubj which,seem
R12810 T18674 T18671 relcl seem,sequences
R12811 T18675 T18676 aux to,be
R12812 T18676 T18674 xcomp be,seem
R12813 T18677 T18676 acomp crucial,be
R12814 T18678 T18677 prep for,crucial
R12815 T18679 T18680 det the,binding
R12816 T18680 T18678 pobj binding,for
R12817 T18681 T18680 prep of,binding
R12818 T18682 T18685 nmod NFAT,proteins
R12819 T18683 T18682 cc and,NFAT
R12820 T18684 T18682 conj NFκB,NFAT
R12821 T18685 T18681 pobj proteins,of
R12822 T18686 T18676 punct ",",be
R12823 T18687 T18676 advmod respectively,be
R12824 T18688 T18667 punct .,reported
R12825 T18689 T18695 advmod Afterwards,purified
R12826 T18690 T18695 punct ",",purified
R12827 T18691 T18693 det the,oligos
R12828 T18692 T18693 compound ds,oligos
R12829 T18693 T18695 nsubjpass oligos,purified
R12830 T18694 T18695 auxpass were,purified
R12831 T18695 T18695 ROOT purified,purified
R12832 T18696 T18695 prep via,purified
R12833 T18697 T18698 compound gel,filtration
R12834 T18698 T18696 pobj filtration,via
R12835 T18699 T18695 advcl using,purified
R12836 T18700 T18701 compound Probe,Quant
R12837 T18701 T18704 compound Quant,Columns
R12838 T18702 T18704 compound G-50,Columns
R12839 T18703 T18704 compound Micro,Columns
R12840 T18704 T18699 dobj Columns,using
R12841 T18705 T18704 punct (,Columns
R12842 T18706 T18704 appos Pharmacia,Columns
R12843 T18707 T18704 punct ),Columns
R12844 T18708 T18695 prep according,purified
R12845 T18709 T18708 prep to,according
R12846 T18710 T18711 det the,manufacturer
R12847 T18711 T18713 poss manufacturer,instructions
R12848 T18712 T18711 case 's,manufacturer
R12849 T18713 T18709 pobj instructions,to
R12850 T18714 T18695 punct .,purified
R13021 T18980 T18980 ROOT Preparation,Preparation
R13022 T18981 T18980 prep of,Preparation
R13023 T18982 T18983 amod nuclear,extracts
R13024 T18983 T18981 pobj extracts,of
R13025 T18984 T18983 cc and,extracts
R13026 T18985 T18987 amod electrophoretic,shift
R13027 T18986 T18987 compound mobility,shift
R13028 T18987 T18988 compound shift,assays
R13029 T18988 T18983 conj assays,extracts
R13030 T18989 T18993 punct (,extracts
R13031 T18990 T18993 nmod EMSA,extracts
R13032 T18991 T18990 punct ),EMSA
R13033 T18992 T18993 compound Nuclear,extracts
R13034 T18993 T18980 appos extracts,Preparation
R13035 T18994 T18993 prep of,extracts
R13036 T18995 T18996 amod purified,PBMCs
R13037 T18996 T18994 pobj PBMCs,of
R13038 T18997 T18980 auxpass were,Preparation
R13039 T18998 T18997 acomp prepared,were
R13040 T18999 T18997 prep according,were
R13041 T19000 T18999 prep to,according
R13042 T19001 T19002 det a,technique
R13043 T19002 T19000 pobj technique,to
R13044 T19003 T19002 acl described,technique
R13045 T19004 T19003 agent by,described
R13046 T19005 T19004 pobj Trede,by
R13047 T19006 T19010 nmod et,]
R13048 T19007 T19008 nmod al.,[
R13049 T19008 T19010 nmod [,]
R13050 T19009 T19010 nummod 27,]
R13051 T19010 T19002 appos ],technique
R13052 T19011 T18999 cc and,according
R13053 T19012 T18999 conj modified,according
R13054 T19013 T19012 prep for,modified
R13055 T19014 T19016 poss our,setup
R13056 T19015 T19016 amod experimental,setup
R13057 T19016 T19013 pobj setup,for
R13058 T19017 T19019 nmod [,]
R13059 T19018 T19019 nummod 56,]
R13060 T19019 T19016 appos ],setup
R13061 T19020 T18997 punct .,were
R13062 T19021 T19022 det The,intensity
R13063 T19022 T19026 nsubj intensity,was
R13064 T19023 T19022 prep of,intensity
R13065 T19024 T19025 amod shifted,bands
R13066 T19025 T19023 pobj bands,of
R13067 T19026 T19026 ROOT was,was
R13068 T19027 T19026 acomp normalized,was
R13069 T19028 T19027 prep to,normalized
R13070 T19029 T19028 pobj bands,to
R13071 T19030 T19029 prep of,bands
R13072 T19031 T19032 amod unstimulated,controls
R13073 T19032 T19030 pobj controls,of
R13074 T19033 T19026 punct .,was
R13075 T19034 T19035 compound Competition,experiments
R13076 T19035 T19035 ROOT experiments,experiments
R13077 T19036 T19035 prep with,experiments
R13078 T19037 T19036 pobj labeled,with
R13079 T19038 T19037 cc and,labeled
R13080 T19039 T19040 amod unlabeled,mutated
R13081 T19040 T19037 conj mutated,labeled
R13082 T19041 T19040 dobj oligos,mutated
R13083 T19042 T19041 prep of,oligos
R13084 T19043 T19045 det the,promoter
R13085 T19044 T19045 compound cytokine,promoter
R13086 T19045 T19047 nmod promoter,sites
R13087 T19046 T19047 amod binding,sites
R13088 T19047 T19042 pobj sites,of
R13089 T19048 T19049 punct (,see
R13090 T19049 T19041 parataxis see,oligos
R13091 T19050 T19049 advmod above,see
R13092 T19051 T19049 punct ),see
R13093 T19052 T19053 auxpass were,carried
R13094 T19053 T19037 conj carried,labeled
R13095 T19054 T19053 prt out,carried
R13096 T19055 T19053 prep in,carried
R13097 T19056 T19055 pobj order,in
R13098 T19057 T19058 aux to,prevent
R13099 T19058 T19056 acl prevent,order
R13100 T19059 T19060 amod non-specific,binding
R13101 T19060 T19058 dobj binding,prevent
R13102 T19061 T19060 prep to,binding
R13103 T19062 T19063 amod nuclear,proteins
R13104 T19063 T19061 pobj proteins,to
R13105 T19064 T19035 punct .,experiments
R13106 T19065 T19080 prep For,added
R13107 T19066 T19067 amod such,experiments
R13108 T19067 T19065 pobj experiments,For
R13109 T19068 T19080 punct ",",added
R13110 T19069 T19080 det an,added
R13111 T19070 T19080 nsubjpass excess,added
R13112 T19071 T19074 punct (,×
R13113 T19072 T19074 nummod 5,×
R13114 T19073 T19072 prep 50,5
R13115 T19074 T19070 appos ×,excess
R13116 T19075 T19074 punct ),×
R13117 T19076 T19074 prep of,×
R13118 T19077 T19078 amod unlabeled,oligos
R13119 T19078 T19076 pobj oligos,of
R13120 T19079 T19080 auxpass was,added
R13121 T19080 T19080 ROOT added,added
R13122 T19081 T19080 prep to,added
R13123 T19082 T19084 det the,extracts
R13124 T19083 T19084 amod nuclear,extracts
R13125 T19084 T19081 pobj extracts,to
R13126 T19085 T19080 punct .,added
R13127 T19086 T19101 prep For,performed
R13128 T19087 T19086 pobj specificity,For
R13129 T19088 T19087 prep of,specificity
R13130 T19089 T19092 amod binding,assays
R13131 T19090 T19092 punct ",",assays
R13132 T19091 T19092 amod supershift,assays
R13133 T19092 T19088 pobj assays,of
R13134 T19093 T19087 prep for,specificity
R13135 T19094 T19093 pobj NFκB,for
R13136 T19095 T19087 prep with,specificity
R13137 T19096 T19099 det a,antibody
R13138 T19097 T19099 amod combined,antibody
R13139 T19098 T19099 nummod p65/50,antibody
R13140 T19099 T19095 pobj antibody,with
R13141 T19100 T19101 auxpass were,performed
R13142 T19101 T19101 ROOT performed,performed
R13143 T19102 T19105 punct (,shown
R13144 T19103 T19105 nsubjpass data,shown
R13145 T19104 T19105 neg not,shown
R13146 T19105 T19101 parataxis shown,performed
R13147 T19106 T19105 punct ),shown
R13148 T19107 T19101 punct .,performed
R13149 T19108 T19109 aux To,exclude
R13150 T19109 T19128 advcl exclude,used
R13151 T19110 T19111 amod non-specific,reactions
R13152 T19111 T19109 dobj reactions,exclude
R13153 T19112 T19111 punct ",",reactions
R13154 T19113 T19116 det a,excess
R13155 T19114 T19116 amod 30-fold,excess
R13156 T19115 T19116 compound molar,excess
R13157 T19116 T19128 nsubjpass excess,used
R13158 T19117 T19116 prep of,excess
R13159 T19118 T19119 compound Oct-1,DNA
R13160 T19119 T19117 pobj DNA,of
R13161 T19120 T19119 punct (,DNA
R13162 T19121 T19122 amod unrelated,DNA
R13163 T19122 T19119 appos DNA,DNA
R13164 T19123 T19119 punct ",",DNA
R13165 T19124 T19119 appos Table,DNA
R13166 T19125 T19124 nummod 1,Table
R13167 T19126 T19119 punct ),DNA
R13168 T19127 T19128 auxpass was,used
R13169 T19128 T19128 ROOT used,used
R13170 T19129 T19128 punct ",",used
R13171 T19130 T19133 nsubj which,compete
R13172 T19131 T19133 aux did,compete
R13173 T19132 T19133 neg not,compete
R13174 T19133 T19128 relcl compete,used
R13175 T19134 T19133 prep with,compete
R13176 T19135 T19136 amod specific,binding
R13177 T19136 T19134 pobj binding,with
R13178 T19137 T19128 punct .,used
R13277 T19396 T19399 punct (,blot
R13278 T19397 T19399 nmod Dot,blot
R13279 T19398 T19399 punct ),blot
R13280 T19399 T19395 appos blot,Immuno
R13281 T19400 T19401 aux To,determine
R13282 T19401 T19478 ccomp determine,extract
R13283 T19402 T19408 mark whether,related
R13284 T19403 T19406 det the,proteins
R13285 T19404 T19406 nmod DNA,proteins
R13286 T19405 T19406 amod binding,proteins
R13287 T19406 T19408 nsubjpass proteins,related
R13288 T19407 T19408 auxpass were,related
R13289 T19408 T19401 ccomp related,determine
R13290 T19409 T19408 prep to,related
R13291 T19410 T19409 pobj NFκB,to
R13292 T19411 T19410 cc and,NFκB
R13293 T19412 T19410 conj NFAT,NFκB
R13294 T19413 T19401 punct ",",determine
R13295 T19414 T19478 ccomp dot,extract
R13296 T19415 T19414 dobj blots,dot
R13297 T19416 T19414 advcl using,dot
R13298 T19417 T19420 det a,minifold
R13299 T19418 T19420 compound SRC96D,minifold
R13300 T19419 T19420 compound SNS,minifold
R13301 T19420 T19416 dobj minifold,using
R13302 T19421 T19422 nsubj I,dot
R13303 T19422 T19478 ccomp dot,extract
R13304 T19423 T19422 dobj blotter,dot
R13305 T19424 T19434 punct (,performed
R13306 T19425 T19434 nsubjpass Schleicher,performed
R13307 T19426 T19425 cc &,Schleicher
R13308 T19427 T19425 conj Schüll,Schleicher
R13309 T19428 T19427 punct ",",Schüll
R13310 T19429 T19427 conj Dassel,Schüll
R13311 T19430 T19429 punct ",",Dassel
R13312 T19431 T19429 conj Germany,Dassel
R13313 T19432 T19434 punct ),performed
R13314 T19433 T19434 auxpass were,performed
R13315 T19434 T19478 ccomp performed,extract
R13316 T19435 T19434 prep with,performed
R13317 T19436 T19439 det the,controls
R13318 T19437 T19439 amod following,controls
R13319 T19438 T19439 amod positive,controls
R13320 T19439 T19435 pobj controls,with
R13321 T19440 T19439 cc and,controls
R13322 T19441 T19439 conj antibodies,controls
R13323 T19442 T19439 punct (,controls
R13324 T19443 T19444 advmod all,from
R13325 T19444 T19439 prep from,controls
R13326 T19445 T19446 compound Santa,Cruz
R13327 T19446 T19447 compound Cruz,Biotechnology
R13328 T19447 T19444 pobj Biotechnology,from
R13329 T19448 T19447 punct ",",Biotechnology
R13330 T19449 T19447 conj Heidelberg,Biotechnology
R13331 T19450 T19449 punct ",",Heidelberg
R13332 T19451 T19447 appos Germany,Biotechnology
R13333 T19452 T19439 punct ),controls
R13334 T19453 T19439 punct :,controls
R13335 T19454 T19455 amod positive,controls
R13336 T19455 T19439 appos controls,controls
R13337 T19456 T19455 punct (,controls
R13338 T19457 T19458 nummod 10,ng/dot
R13339 T19458 T19455 appos ng/dot,controls
R13340 T19459 T19455 punct ),controls
R13341 T19460 T19439 punct :,controls
R13342 T19461 T19462 compound NFκB,p52
R13343 T19462 T19439 appos p52,controls
R13344 T19463 T19465 punct (,kD
R13345 T19464 T19465 nummod 80,kD
R13346 T19465 T19462 appos kD,p52
R13347 T19466 T19439 punct ),controls
R13348 T19467 T19434 dobj sc-4095WB,performed
R13349 T19468 T19467 punct ",",sc-4095WB
R13350 T19469 T19467 appos c-Rel,sc-4095WB
R13351 T19470 T19472 punct (,kD
R13352 T19471 T19472 nummod 61,kD
R13353 T19472 T19469 appos kD,c-Rel
R13354 T19473 T19472 punct ),kD
R13355 T19474 T19469 amod sc-4030WB,c-Rel
R13356 T19475 T19478 punct ;,extract
R13357 T19476 T19478 nsubj Jurkat,extract
R13358 T19477 T19478 amod nuclear,extract
R13359 T19478 T19478 ROOT extract,extract
R13360 T19479 T19478 punct ",",extract
R13361 T19480 T19478 dep PMA-stimulated,extract
R13362 T19481 T19478 punct ;,extract
R13363 T19482 T19483 amod primary,antibodies
R13364 T19483 T19478 dobj antibodies,extract
R13365 T19484 T19483 punct (,antibodies
R13366 T19485 T19486 nummod 1,μg
R13367 T19486 T19488 compound μg,dot
R13368 T19487 T19488 compound /,dot
R13369 T19488 T19483 appos dot,antibodies
R13370 T19489 T19483 punct ),antibodies
R13371 T19490 T19483 punct :,antibodies
R13372 T19491 T19492 compound anti-NFκB,p50
R13373 T19492 T19506 nmod p50,p52
R13374 T19493 T19494 punct (,NLS
R13375 T19494 T19492 appos NLS,p50
R13376 T19495 T19494 punct ),NLS
R13377 T19496 T19499 amod sc-114,p65
R13378 T19497 T19499 punct ",",p65
R13379 T19498 T19499 amod anti-NFκB,p65
R13380 T19499 T19492 appos p65,p50
R13381 T19500 T19499 punct (,p65
R13382 T19501 T19499 appos A,p65
R13383 T19502 T19499 punct ),p65
R13384 T19503 T19506 nmod sc-109,p52
R13385 T19504 T19503 punct ",",sc-109
R13386 T19505 T19506 amod anti-NFκB,p52
R13387 T19506 T19483 appos p52,antibodies
R13388 T19507 T19506 punct (,p52
R13389 T19508 T19506 appos 447,p52
R13390 T19509 T19506 punct ),p52
R13391 T19510 T19506 conj sc-848,p52
R13392 T19511 T19510 punct ",",sc-848
R13393 T19512 T19516 det a,antiserum
R13394 T19513 T19516 nmod rabbit,antiserum
R13395 T19514 T19516 nmod polyclonal,antiserum
R13396 T19515 T19516 amod IgG1,antiserum
R13397 T19516 T19510 conj antiserum,sc-848
R13398 T19517 T19516 punct ",",antiserum
R13399 T19518 T19516 conj anti-c-rel,antiserum
R13400 T19519 T19518 punct (,anti-c-rel
R13401 T19520 T19518 appos N466,anti-c-rel
R13402 T19521 T19518 punct ),anti-c-rel
R13403 T19522 T19516 conj sc-272,antiserum
R13404 T19523 T19522 punct ",",sc-272
R13405 T19524 T19522 conj anti-NFATc2,sc-272
R13406 T19525 T19524 punct (,anti-NFATc2
R13407 T19526 T19524 appos M-20,anti-NFATc2
R13408 T19527 T19524 punct ),anti-NFATc2
R13409 T19528 T19540 nmod sc-1151,antisera
R13410 T19529 T19528 punct ",",sc-1151
R13411 T19530 T19528 conj anti-NFATc1,sc-1151
R13412 T19531 T19530 punct (,anti-NFATc1
R13413 T19532 T19530 appos K-18,anti-NFATc1
R13414 T19533 T19530 punct ),anti-NFATc1
R13415 T19534 T19528 conj sc-1149,sc-1151
R13416 T19535 T19534 punct ",",sc-1149
R13417 T19536 T19540 nummod two,antisera
R13418 T19537 T19540 nmod goat,antisera
R13419 T19538 T19540 nmod polyclonal,antisera
R13420 T19539 T19540 amod IgG1,antisera
R13421 T19540 T19522 dep antisera,sc-272
R13422 T19541 T19483 punct ;,antibodies
R13423 T19542 T19543 amod secondary,antibodies
R13424 T19543 T19483 appos antibodies,antibodies
R13425 T19544 T19548 punct (,dot
R13426 T19545 T19546 nummod 0.8,μg
R13427 T19546 T19548 compound μg,dot
R13428 T19547 T19548 compound /,dot
R13429 T19548 T19543 appos dot,antibodies
R13430 T19549 T19548 punct ),dot
R13431 T19550 T19543 punct :,antibodies
R13432 T19551 T19552 compound goat,anti-rabbit
R13433 T19552 T19555 compound anti-rabbit,sc-2007
R13434 T19553 T19554 compound IgG,AP-conjugate
R13435 T19554 T19555 compound AP-conjugate,sc-2007
R13436 T19555 T19543 appos sc-2007,antibodies
R13437 T19556 T19555 punct ",",sc-2007
R13438 T19557 T19555 cc and,sc-2007
R13439 T19558 T19559 amod donkey,anti-goat
R13440 T19559 T19562 amod anti-goat,sc-2022
R13441 T19560 T19561 compound IgG,AP-conjugate
R13442 T19561 T19562 compound AP-conjugate,sc-2022
R13443 T19562 T19555 conj sc-2022,sc-2007
R13444 T19563 T19478 punct .,extract
R13445 T19564 T19566 det The,proteins
R13446 T19565 T19566 amod nuclear,proteins
R13447 T19566 T19568 nsubjpass proteins,blotted
R13448 T19567 T19568 auxpass were,blotted
R13449 T19568 T19568 ROOT blotted,blotted
R13450 T19569 T19568 prep onto,blotted
R13451 T19570 T19572 det a,membrane
R13452 T19571 T19572 amod nitrocellulose,membrane
R13453 T19572 T19569 pobj membrane,onto
R13454 T19573 T19574 punct (,Bio-Rad
R13455 T19574 T19572 appos Bio-Rad,membrane
R13456 T19575 T19568 punct ),blotted
R13457 T19576 T19568 punct .,blotted
R13458 T19577 T19594 prep After,incubated
R13459 T19578 T19577 pcomp blocking,After
R13460 T19579 T19578 prep with,blocking
R13461 T19580 T19581 nummod PBS/3,%
R13462 T19581 T19584 nmod %,Fluka
R13463 T19582 T19584 nmod BSA,Fluka
R13464 T19583 T19584 punct (,Fluka
R13465 T19584 T19579 pobj Fluka,with
R13466 T19585 T19584 punct ",",Fluka
R13467 T19586 T19584 conj Deisenhofen,Fluka
R13468 T19587 T19586 punct ",",Deisenhofen
R13469 T19588 T19586 conj Germany,Deisenhofen
R13470 T19589 T19584 punct ),Fluka
R13471 T19590 T19594 punct ",",incubated
R13472 T19591 T19592 det the,blot
R13473 T19592 T19594 nsubjpass blot,incubated
R13474 T19593 T19594 auxpass was,incubated
R13475 T19594 T19594 ROOT incubated,incubated
R13476 T19595 T19594 advmod overnight,incubated
R13477 T19596 T19594 prep with,incubated
R13478 T19597 T19599 det the,antibodies
R13479 T19598 T19599 amod primary,antibodies
R13480 T19599 T19596 pobj antibodies,with
R13481 T19600 T19599 acl diluted,antibodies
R13482 T19601 T19600 npadvmod 1:2000,diluted
R13483 T19602 T19601 prep in,1:2000
R13484 T19603 T19604 nummod PBS/1,%
R13485 T19604 T19602 pobj %,in
R13486 T19605 T19600 npadvmod BSA,diluted
R13487 T19606 T19607 punct ",",washed
R13488 T19607 T19594 dep washed,incubated
R13489 T19608 T19607 advmod again,washed
R13490 T19609 T19607 cc and,washed
R13491 T19610 T19607 conj incubated,washed
R13492 T19611 T19610 prep with,incubated
R13493 T19612 T19616 det the,antibody
R13494 T19613 T19616 amod alkaline,antibody
R13495 T19614 T19616 amod phosphatase-conjugated,antibody
R13496 T19615 T19616 amod secondary,antibody
R13497 T19616 T19611 pobj antibody,with
R13498 T19617 T19616 punct (,antibody
R13499 T19618 T19616 appos 1:500,antibody
R13500 T19619 T19618 prep in,1:500
R13501 T19620 T19621 nummod PBS/1,%
R13502 T19621 T19622 compound %,BSA
R13503 T19622 T19619 pobj BSA,in
R13504 T19623 T19616 punct ),antibody
R13505 T19624 T19594 punct .,incubated
R13506 T19625 T19626 det The,blot
R13507 T19626 T19628 nsubjpass blot,developed
R13508 T19627 T19628 auxpass was,developed
R13509 T19628 T19628 ROOT developed,developed
R13510 T19629 T19628 advcl using,developed
R13511 T19630 T19632 det the,®
R13512 T19631 T19632 compound Vectastain,®
R13513 T19632 T19629 dobj ®,using
R13514 T19633 T19629 conj staining,using
R13515 T19634 T19633 dobj kit,staining
R13516 T19635 T19634 punct (,kit
R13517 T19636 T19638 compound Vector,Inc.
R13518 T19637 T19638 compound Laboratories,Inc.
R13519 T19638 T19634 appos Inc.,kit
R13520 T19639 T19628 punct .,developed
R13704 T20005 T20011 nsubjpass measurements,harvested
R13705 T20006 T20011 nsubjpass Supernatants,harvested
R13706 T20007 T20006 prep of,Supernatants
R13707 T20008 T20009 compound cell,cultures
R13708 T20009 T20007 pobj cultures,of
R13709 T20010 T20011 auxpass were,harvested
R13710 T20011 T20011 ROOT harvested,harvested
R13711 T20012 T20033 npadvmod 3,stored
R13712 T20013 T20012 punct ",",3
R13713 T20014 T20012 conj 6,3
R13714 T20015 T20014 punct ",",6
R13715 T20016 T20012 appos 9,3
R13716 T20017 T20033 punct ",",stored
R13717 T20018 T20029 nummod 12,hours
R13718 T20019 T20020 punct ",",18
R13719 T20020 T20022 nummod 18,24
R13720 T20021 T20022 punct ",",24
R13721 T20022 T20018 appos 24,12
R13722 T20023 T20024 punct ",",30
R13723 T20024 T20022 prep 30,24
R13724 T20025 T20024 punct ",",30
R13725 T20026 T20024 conj 36,30
R13726 T20027 T20026 cc and,36
R13727 T20028 T20026 conj 48,36
R13728 T20029 T20030 npadvmod hours,after
R13729 T20030 T20033 prep after,stored
R13730 T20031 T20030 pobj stimulation,after
R13731 T20032 T20030 cc and,after
R13732 T20033 T20011 oprd stored,harvested
R13733 T20034 T20033 prep at,stored
R13734 T20035 T20037 nummod -80,C
R13735 T20036 T20037 nummod °,C
R13736 T20037 T20034 pobj C,at
R13737 T20038 T20039 mark until,used
R13738 T20039 T20033 advcl used,stored
R13739 T20040 T20039 cc and,used
R13740 T20041 T20039 conj thawed,used
R13741 T20042 T20043 advmod only,once
R13742 T20043 T20041 advmod once,thawed
R13743 T20044 T20033 punct .,stored
R13744 T20045 T20053 nsubjpass IFNγ,determined
R13745 T20046 T20045 punct ",",IFNγ
R13746 T20047 T20045 conj TNFα,IFNγ
R13747 T20048 T20047 punct ",",TNFα
R13748 T20049 T20047 conj IL-1,TNFα
R13749 T20050 T20049 cc and,IL-1
R13750 T20051 T20049 conj IL-6,IL-1
R13751 T20052 T20053 auxpass were,determined
R13752 T20053 T20053 ROOT determined,determined
R13753 T20054 T20053 advcl using,determined
R13754 T20055 T20056 det an,ELISA
R13755 T20056 T20054 dobj ELISA,using
R13756 T20057 T20056 prep from,ELISA
R13757 T20058 T20059 compound Bender,Systems
R13758 T20059 T20057 pobj Systems,from
R13759 T20060 T20059 punct (,Systems
R13760 T20061 T20059 npadvmod Vienna,Systems
R13761 T20062 T20061 punct ",",Vienna
R13762 T20063 T20061 appos Austria,Vienna
R13763 T20064 T20061 punct ),Vienna
R13764 T20065 T20061 punct ",",Vienna
R13765 T20066 T20061 conj IL-1RA,Vienna
R13766 T20067 T20066 cc and,IL-1RA
R13767 T20068 T20066 conj IL-8,IL-1RA
R13768 T20069 T20054 prep by,using
R13769 T20070 T20071 det an,ELISA
R13770 T20071 T20069 pobj ELISA,by
R13771 T20072 T20071 prep from,ELISA
R13772 T20073 T20074 compound R&D,Systems
R13773 T20074 T20072 pobj Systems,from
R13774 T20075 T20074 punct (,Systems
R13775 T20076 T20071 conj Wiesbaden-Nordenstadt,ELISA
R13776 T20077 T20076 punct ",",Wiesbaden-Nordenstadt
R13777 T20078 T20076 conj Germany,Wiesbaden-Nordenstadt
R13778 T20079 T20076 punct ),Wiesbaden-Nordenstadt
R13779 T20080 T20053 punct ",",determined
R13780 T20081 T20053 cc and,determined
R13781 T20082 T20084 nsubj TGFβ,using
R13782 T20083 T20082 nummod 1,TGFβ
R13783 T20084 T20053 conj using,determined
R13784 T20085 T20086 det an,ELISA
R13785 T20086 T20084 dobj ELISA,using
R13786 T20087 T20089 mark as,described
R13787 T20088 T20089 advmod previously,described
R13788 T20089 T20084 advcl described,using
R13789 T20090 T20092 nmod [,]
R13790 T20091 T20092 nummod 57,]
R13791 T20092 T20089 dobj ],described
R13792 T20093 T20084 punct .,using
R13793 T20094 T20106 nsubjpass Quantification,done
R13794 T20095 T20094 prep of,Quantification
R13795 T20096 T20095 pobj IL-2,of
R13796 T20097 T20094 prep as,Quantification
R13797 T20098 T20099 det an,indicator
R13798 T20099 T20097 pobj indicator,as
R13799 T20100 T20099 prep for,indicator
R13800 T20101 T20102 det the,bioactivity
R13801 T20102 T20100 pobj bioactivity,for
R13802 T20103 T20102 prep of,bioactivity
R13803 T20104 T20103 pobj IL-1,of
R13804 T20105 T20106 auxpass was,done
R13805 T20106 T20106 ROOT done,done
R13806 T20107 T20109 mark as,described
R13807 T20108 T20109 advmod previously,described
R13808 T20109 T20106 advcl described,done
R13809 T20110 T20112 nmod [,]
R13810 T20111 T20112 nummod 46,]
R13811 T20112 T20109 dobj ],described
R13812 T20113 T20106 punct .,done
R13813 T20114 T20116 nsubjpass Samples,diluted
R13814 T20115 T20116 auxpass were,diluted
R13815 T20116 T20116 ROOT diluted,diluted
R13816 T20117 T20116 prep in,diluted
R13817 T20118 T20120 det the,buffer
R13818 T20119 T20120 amod same,buffer
R13819 T20120 T20117 pobj buffer,in
R13820 T20121 T20120 prep as,buffer
R13821 T20122 T20121 pobj that,as
R13822 T20123 T20122 acl used,that
R13823 T20124 T20123 prep for,used
R13824 T20125 T20126 det the,standards
R13825 T20126 T20124 pobj standards,for
R13826 T20127 T20116 punct .,diluted
R13827 T20128 T20129 det All,cytokines
R13828 T20129 T20131 nsubjpass cytokines,quantified
R13829 T20130 T20131 auxpass were,quantified
R13830 T20131 T20131 ROOT quantified,quantified
R13831 T20132 T20131 advcl using,quantified
R13832 T20133 T20136 det an,reader
R13833 T20134 T20136 nmod ELISA,reader
R13834 T20135 T20136 compound plate,reader
R13835 T20136 T20132 dobj reader,using
R13836 T20137 T20136 punct (,reader
R13837 T20138 T20139 compound Anthos,Labotec
R13838 T20139 T20136 appos Labotec,reader
R13839 T20140 T20139 punct ",",Labotec
R13840 T20141 T20139 conj Salzburg,Labotec
R13841 T20142 T20141 punct ",",Salzburg
R13842 T20143 T20141 conj Austria,Salzburg
R13843 T20144 T20143 cc or,Austria
R13844 T20145 T20146 compound Microplate,Reader
R13845 T20146 T20143 conj Reader,Austria
R13846 T20147 T20146 punct ",",Reader
R13847 T20148 T20146 conj BioRad,Reader
R13848 T20149 T20136 punct ),reader
R13849 T20150 T20131 punct .,quantified
R13850 T20151 T20152 compound Cytokine,amounts
R13851 T20152 T20153 nsubj amounts,were
R13852 T20153 T20153 ROOT were,were
R13853 T20154 T20153 dep all,were
R13854 T20155 T20153 prep within,were
R13855 T20156 T20157 det the,range
R13856 T20157 T20155 pobj range,within
R13857 T20158 T20157 prep of,range
R13858 T20159 T20161 det the,curve
R13859 T20160 T20161 amod standard,curve
R13860 T20161 T20158 pobj curve,of
R13861 T20162 T20153 punct .,were
R13862 T20163 T20164 advmod Only,stimulation
R13863 T20164 T20167 nsubj stimulation,observed
R13864 T20165 T20164 prep of,stimulation
R13865 T20166 T20165 pobj PBMC,of
R13866 T20167 T20167 ROOT observed,observed
R13867 T20168 T20167 prep in,observed
R13868 T20169 T20168 pobj donors,in
R13869 T20170 T20169 acl showing,donors
R13870 T20171 T20174 det no,release
R13871 T20172 T20174 amod spontaneous,release
R13872 T20173 T20174 compound cytokine,release
R13873 T20174 T20170 dobj release,showing
R13874 T20175 T20176 auxpass was,included
R13875 T20176 T20167 ccomp included,observed
R13876 T20177 T20176 prep in,included
R13877 T20178 T20179 det the,statistics
R13878 T20179 T20177 pobj statistics,in
R13879 T20180 T20167 punct .,observed
R14153 T20612 T20631 nsubjpass Inhibition,incubated
R14154 T20613 T20612 prep of,Inhibition
R14155 T20614 T20615 compound transcription,factors
R14156 T20615 T20613 pobj factors,of
R14157 T20616 T20617 aux To,inhibit
R14158 T20617 T20631 advcl inhibit,incubated
R14159 T20618 T20617 dobj translocation,inhibit
R14160 T20619 T20618 cc and,translocation
R14161 T20620 T20618 conj binding,translocation
R14162 T20621 T20620 prep of,binding
R14163 T20622 T20623 compound transcription,factors
R14164 T20623 T20621 pobj factors,of
R14165 T20624 T20617 prep to,inhibit
R14166 T20625 T20627 det the,promoter
R14167 T20626 T20627 compound IL-1RA,promoter
R14168 T20627 T20624 pobj promoter,to
R14169 T20628 T20631 punct ",",incubated
R14170 T20629 T20631 nsubjpass PBMC,incubated
R14171 T20630 T20631 auxpass were,incubated
R14172 T20631 T20631 ROOT incubated,incubated
R14173 T20632 T20631 prep for,incubated
R14174 T20633 T20634 nummod 1,h
R14175 T20634 T20632 pobj h,for
R14176 T20635 T20634 prep with,h
R14177 T20636 T20635 pobj each,with
R14178 T20637 T20636 prep of,each
R14179 T20638 T20640 det the,substances
R14180 T20639 T20640 amod following,substances
R14181 T20640 T20637 pobj substances,of
R14182 T20641 T20644 punct (,based
R14183 T20642 T20644 nsubjpass concentrations,based
R14184 T20643 T20644 auxpass were,based
R14185 T20644 T20631 conj based,incubated
R14186 T20645 T20644 prep upon,based
R14187 T20646 T20647 nummod 50,%
R14188 T20647 T20648 compound %,inhibition
R14189 T20648 T20645 pobj inhibition,upon
R14190 T20649 T20644 punct ),based
R14191 T20650 T20654 punct :,ml
R14192 T20651 T20652 nummod 50,μg
R14193 T20652 T20654 compound μg,ml
R14194 T20653 T20654 compound /,ml
R14195 T20654 T20654 ROOT ml,ml
R14196 T20655 T20654 prep of,ml
R14197 T20656 T20655 pobj CAPE,of
R14198 T20657 T20658 punct (,caffeic-3
R14199 T20658 T20654 dep caffeic-3,ml
R14200 T20659 T20661 punct ",4",dihydroxycinnamic-acid-phenyl-ester
R14201 T20660 T20661 punct -,dihydroxycinnamic-acid-phenyl-ester
R14202 T20661 T20658 appos dihydroxycinnamic-acid-phenyl-ester,caffeic-3
R14203 T20662 T20661 punct ),dihydroxycinnamic-acid-phenyl-ester
R14204 T20663 T20658 punct ",",caffeic-3
R14205 T20664 T20665 punct (,Biomol
R14206 T20665 T20658 appos Biomol,caffeic-3
R14207 T20666 T20665 punct ",",Biomol
R14208 T20667 T20665 npadvmod Hamburg,Biomol
R14209 T20668 T20667 punct ",",Hamburg
R14210 T20669 T20667 appos Germany,Hamburg
R14211 T20670 T20667 punct ),Hamburg
R14212 T20671 T20665 punct ;,Biomol
R14213 T20672 T20674 nummod 400,cyclosporin
R14214 T20673 T20674 compound ng/ml,cyclosporin
R14215 T20674 T20675 compound cyclosporin,A
R14216 T20675 T20678 det A,Biosciences
R14217 T20676 T20678 punct (,Biosciences
R14218 T20677 T20678 compound Calbiochem-Merck,Biosciences
R14219 T20678 T20658 appos Biosciences,caffeic-3
R14220 T20679 T20678 punct ",",Biosciences
R14221 T20680 T20681 compound Bad,Soden
R14222 T20681 T20678 conj Soden,Biosciences
R14223 T20682 T20681 punct ",",Soden
R14224 T20683 T20681 conj Germany,Soden
R14225 T20684 T20681 punct ),Soden
R14226 T20685 T20678 punct ;,Biosciences
R14227 T20686 T20687 nummod 10,μg
R14228 T20687 T20690 nmod μg,cycloheximide
R14229 T20688 T20690 nmod /,cycloheximide
R14230 T20689 T20690 compound ml,cycloheximide
R14231 T20690 T20678 conj cycloheximide,Biosciences
R14232 T20691 T20694 punct (,Biotechnology
R14233 T20692 T20693 compound Santa,Cruz
R14234 T20693 T20694 compound Cruz,Biotechnology
R14235 T20694 T20690 appos Biotechnology,cycloheximide
R14236 T20695 T20690 punct ),cycloheximide
R14237 T20696 T20699 advmod prior,with
R14238 T20697 T20696 prep to,prior
R14239 T20698 T20697 pobj incubation,to
R14240 T20699 T20658 prep with,caffeic-3
R14241 T20700 T20699 pobj GP,with
R14242 T20701 T20658 punct .,caffeic-3
R14243 T20702 T20703 compound Band,shifts
R14244 T20703 T20705 nsubjpass shifts,determined
R14245 T20704 T20705 auxpass were,determined
R14246 T20705 T20705 ROOT determined,determined
R14247 T20706 T20705 prep after,determined
R14248 T20707 T20709 nummod 1,incubation
R14249 T20708 T20709 compound h,incubation
R14250 T20709 T20706 pobj incubation,after
R14251 T20710 T20709 prep with,incubation
R14252 T20711 T20710 pobj GP,with
R14253 T20712 T20713 mark as,described
R14254 T20713 T20709 advcl described,incubation
R14255 T20714 T20713 advmod before,described
R14256 T20715 T20709 punct ",",incubation
R14257 T20716 T20709 prep including,incubation
R14258 T20717 T20718 amod mutated,oligos
R14259 T20718 T20716 pobj oligos,including
R14260 T20719 T20718 prep for,oligos
R14261 T20720 T20719 pobj NFIL-6,for
R14262 T20721 T20731 punct (,GGG
R14263 T20722 T20727 compound TTA,GCG
R14264 T20723 T20727 compound CAA,GCG
R14265 T20724 T20727 compound CAG,GCG
R14266 T20725 T20727 compound TGG,GCG
R14267 T20726 T20727 compound ATT,GCG
R14268 T20727 T20731 compound GCG,GGG
R14269 T20728 T20729 compound ACA,CTT
R14270 T20729 T20731 compound CTT,GGG
R14271 T20730 T20731 compound AGT,GGG
R14272 T20731 T20720 appos GGG,NFIL-6
R14273 T20732 T20731 punct ),GGG
R14274 T20733 T20720 cc and,NFIL-6
R14275 T20734 T20745 compound NFATP2/3,TCT
R14276 T20735 T20740 punct (,GTA
R14277 T20736 T20740 compound GGC,GTA
R14278 T20737 T20740 compound GCA,GTA
R14279 T20738 T20740 compound GAA,GTA
R14280 T20739 T20740 compound AAG,GTA
R14281 T20740 T20745 compound GTA,TCT
R14282 T20741 T20745 compound AAA,TCT
R14283 T20742 T20745 compound TAT,TCT
R14284 T20743 T20745 compound TTA,TCT
R14285 T20744 T20745 compound CTA,TCT
R14286 T20745 T20720 conj TCT,NFIL-6
R14287 T20746 T20718 punct ),oligos
R14288 T20747 T20748 amod binding,sites
R14289 T20748 T20716 pobj sites,including
R14290 T20749 T20748 prep within,sites
R14291 T20750 T20752 det the,promoter
R14292 T20751 T20752 compound IL-1RA,promoter
R14293 T20752 T20749 pobj promoter,within
R14294 T20753 T20705 punct .,determined
R14295 T20754 T20755 compound PBMC,RNA
R14296 T20755 T20756 nsubj RNA,was
R14297 T20756 T20756 ROOT was,was
R14298 T20757 T20756 acomp isolated,was
R14299 T20758 T20757 prep with,isolated
R14300 T20759 T20761 det an,kit
R14301 T20760 T20761 compound RNeasy,kit
R14302 T20761 T20758 pobj kit,with
R14303 T20762 T20761 punct (,kit
R14304 T20763 T20761 appos Qiagen,kit
R14305 T20764 T20763 punct ",",Qiagen
R14306 T20765 T20763 appos Germany,Qiagen
R14307 T20766 T20765 punct ),Germany
R14308 T20767 T20761 cc and,kit
R14309 T20768 T20769 compound messenger,RNA
R14310 T20769 T20771 nsubjpass RNA,transcribed
R14311 T20770 T20771 auxpass was,transcribed
R14312 T20771 T20756 conj transcribed,was
R14313 T20772 T20771 prep into,transcribed
R14314 T20773 T20772 pobj cDNA,into
R14315 T20774 T20771 prep with,transcribed
R14316 T20775 T20778 compound Reactin,Strand
R14317 T20776 T20778 compound Ready,Strand
R14318 T20777 T20778 compound First,Strand
R14319 T20778 T20779 compound Strand,kit
R14320 T20779 T20774 pobj kit,with
R14321 T20780 T20779 punct (,kit
R14322 T20781 T20779 appos Biomol,kit
R14323 T20782 T20779 punct ),kit
R14324 T20783 T20771 cc and,transcribed
R14325 T20784 T20771 conj analysed,transcribed
R14326 T20785 T20784 prep for,analysed
R14327 T20786 T20785 pobj IL-1RA,for
R14328 T20787 T20786 cc and,IL-1RA
R14329 T20788 T20786 conj GAPDH,IL-1RA
R14330 T20789 T20785 pobj transcripts,for
R14331 T20790 T20789 prep by,transcripts
R14332 T20791 T20790 pobj PCR,by
R14333 T20792 T20784 prep with,analysed
R14334 T20793 T20794 det a,HotStart
R14335 T20794 T20799 nmod HotStart,mastermix
R14336 T20795 T20799 punct """",mastermix
R14337 T20796 T20799 amod sweet,mastermix
R14338 T20797 T20799 punct """",mastermix
R14339 T20798 T20799 compound PCR,mastermix
R14340 T20799 T20856 nsubj mastermix,following
R14341 T20800 T20799 punct (,mastermix
R14342 T20801 T20799 appos Biomol,mastermix
R14343 T20802 T20799 punct ),mastermix
R14344 T20803 T20806 punct (,C
R14345 T20804 T20805 nummod 95,°
R14346 T20805 T20806 compound °,C
R14347 T20806 T20799 appos C,mastermix
R14348 T20807 T20813 punct ",",C
R14349 T20808 T20809 nummod 30,sec
R14350 T20809 T20813 npadvmod sec,C
R14351 T20810 T20813 punct ",",C
R14352 T20811 T20813 nummod 55,C
R14353 T20812 T20813 compound °,C
R14354 T20813 T20799 conj C,mastermix
R14355 T20814 T20813 punct ",",C
R14356 T20815 T20816 nummod 30,sec
R14357 T20816 T20813 appos sec,C
R14358 T20817 T20816 punct ",",sec
R14359 T20818 T20820 nummod 72,C
R14360 T20819 T20820 compound °,C
R14361 T20820 T20813 conj C,C
R14362 T20821 T20820 punct ",",C
R14363 T20822 T20823 nummod 30,sec
R14364 T20823 T20856 nsubj sec,following
R14365 T20824 T20823 punct ",",sec
R14366 T20825 T20826 nummod 25,cycles
R14367 T20826 T20823 conj cycles,sec
R14368 T20827 T20826 prep for,cycles
R14369 T20828 T20827 pobj IL-1RA,for
R14370 T20829 T20828 cc and,IL-1RA
R14371 T20830 T20831 nummod 94,°
R14372 T20831 T20832 compound °,C
R14373 T20832 T20828 conj C,IL-1RA
R14374 T20833 T20832 prep for,C
R14375 T20834 T20835 nummod 30,sec
R14376 T20835 T20833 pobj sec,for
R14377 T20836 T20835 punct ",",sec
R14378 T20837 T20838 nummod 50,°
R14379 T20838 T20839 compound °,C
R14380 T20839 T20832 conj C,C
R14381 T20840 T20823 prep for,sec
R14382 T20841 T20856 nummod 30,following
R14383 T20842 T20856 nsubj sec,following
R14384 T20843 T20842 cc and,sec
R14385 T20844 T20845 nummod 72,°
R14386 T20845 T20846 compound °,C
R14387 T20846 T20842 conj C,sec
R14388 T20847 T20846 prep for,C
R14389 T20848 T20849 nummod 45,sec
R14390 T20849 T20847 pobj sec,for
R14391 T20850 T20849 punct ",",sec
R14392 T20851 T20852 nummod 25,cycles
R14393 T20852 T20849 appos cycles,sec
R14394 T20853 T20852 prep for,cycles
R14395 T20854 T20853 pobj GAPDH,for
R14396 T20855 T20852 punct ),cycles
R14397 T20856 T20771 conj following,transcribed
R14398 T20857 T20858 nummod 18,h
R14399 T20858 T20859 compound h,incubation
R14400 T20859 T20856 pobj incubation,following
R14401 T20860 T20859 prep with,incubation
R14402 T20861 T20860 pobj GP,with
R14403 T20862 T20771 punct .,transcribed
R14404 T20863 T20864 compound IL-1RA,protein
R14405 T20864 T20866 nsubjpass protein,measured
R14406 T20865 T20866 auxpass was,measured
R14407 T20866 T20866 ROOT measured,measured
R14408 T20867 T20866 prep in,measured
R14409 T20868 T20869 det the,supernatant
R14410 T20869 T20867 pobj supernatant,in
R14411 T20870 T20866 agent by,measured
R14412 T20871 T20870 pobj ELISA,by
R14413 T20872 T20866 prep after,measured
R14414 T20873 T20875 nummod 24,incubation
R14415 T20874 T20875 compound h,incubation
R14416 T20875 T20872 pobj incubation,after
R14417 T20876 T20875 prep with,incubation
R14418 T20877 T20876 pobj GP,with
R14419 T20878 T20866 punct .,measured
R14585 T21188 T21189 compound Statistical,analysis
R14586 T21189 T21194 nsubjpass analysis,used
R14587 T21190 T21192 det The,test
R14588 T21191 T21192 compound Kolmogorow-Smirnov,test
R14589 T21192 T21194 nsubjpass test,used
R14590 T21193 T21194 auxpass was,used
R14591 T21194 T21194 ROOT used,used
R14592 T21195 T21196 aux to,evaluate
R14593 T21196 T21194 xcomp evaluate,used
R14594 T21197 T21196 punct ",",evaluate
R14595 T21198 T21209 mark whether,distributed
R14596 T21199 T21200 compound cytokine,amounts
R14597 T21200 T21206 nmod amounts,factors
R14598 T21201 T21200 cc and,amounts
R14599 T21202 T21203 amod binding,activities
R14600 T21203 T21200 conj activities,amounts
R14601 T21204 T21205 aux to,transcription
R14602 T21205 T21206 compound transcription,factors
R14603 T21206 T21209 nsubjpass factors,distributed
R14604 T21207 T21209 auxpass were,distributed
R14605 T21208 T21209 advmod normally,distributed
R14606 T21209 T21194 advcl distributed,used
R14607 T21210 T21194 punct .,used
R14608 T21211 T21212 compound Correlation,coefficients
R14609 T21212 T21217 nsubjpass coefficients,analyzed
R14610 T21213 T21212 cc and,coefficients
R14611 T21214 T21215 amod corresponding,significances
R14612 T21215 T21212 conj significances,coefficients
R14613 T21216 T21217 auxpass were,analyzed
R14614 T21217 T21217 ROOT analyzed,analyzed
R14615 T21218 T21217 agent by,analyzed
R14616 T21219 T21221 det the,test
R14617 T21220 T21221 compound Pearson,test
R14618 T21221 T21218 pobj test,by
R14619 T21222 T21221 punct (,test
R14620 T21223 T21224 amod normal,distribution
R14621 T21224 T21221 appos distribution,test
R14622 T21225 T21221 punct ),test
R14623 T21226 T21221 cc or,test
R14624 T21227 T21229 det the,test
R14625 T21228 T21229 compound Spearman,test
R14626 T21229 T21221 conj test,test
R14627 T21230 T21229 punct (,test
R14628 T21231 T21232 amod non-normal,distribution
R14629 T21232 T21229 appos distribution,test
R14630 T21233 T21229 punct ),test
R14631 T21234 T21217 punct .,analyzed
R14632 T21235 T21236 aux To,compare
R14633 T21236 T21256 advcl compare,calculated
R14634 T21237 T21238 amod experimental,data
R14635 T21238 T21236 dobj data,compare
R14636 T21239 T21236 prep to,compare
R14637 T21240 T21242 det a,value
R14638 T21241 T21242 amod theoretical,value
R14639 T21242 T21239 pobj value,to
R14640 T21243 T21249 punct (,vs
R14641 T21244 T21249 prep for,vs
R14642 T21245 T21244 pobj example,for
R14643 T21246 T21248 compound GP,TSST-1
R14644 T21247 T21248 compound +,TSST-1
R14645 T21248 T21249 nsubj TSST-1,vs
R14646 T21249 T21242 parataxis vs,value
R14647 T21250 T21252 nmod GP/TSST,calc
R14648 T21251 T21252 nummod -1,calc
R14649 T21252 T21249 dobj calc,vs
R14650 T21253 T21236 punct .,compare
R14651 T21254 T21256 punct ),calculated
R14652 T21255 T21256 nsubj we,calculated
R14653 T21256 T21256 ROOT calculated,calculated
R14654 T21257 T21258 det the,sum
R14655 T21258 T21256 dobj sum,calculated
R14656 T21259 T21258 prep of,sum
R14657 T21260 T21262 det the,effects
R14658 T21261 T21262 amod individual,effects
R14659 T21262 T21259 pobj effects,of
R14660 T21263 T21256 cc and,calculated
R14661 T21264 T21256 conj added,calculated
R14662 T21265 T21266 det these,values
R14663 T21266 T21264 dobj values,added
R14664 T21267 T21264 prep into,added
R14665 T21268 T21269 compound Fig.,1B
R14666 T21269 T21267 pobj 1B,into
R14667 T21270 T21269 punct ",",1B
R14668 T21271 T21269 appos 3,1B
R14669 T21272 T21271 punct ",",3
R14670 T21273 T21269 appos 4,1B
R14671 T21274 T21269 punct ",",1B
R14672 T21275 T21269 appos 5,1B
R14673 T21276 T21269 punct ",",1B
R14674 T21277 T21269 cc and,1B
R14675 T21278 T21269 conj 6,1B
R14676 T21279 T21256 punct .,calculated
R14677 T21280 T21280 ROOT Significances,Significances
R14678 T21281 T21280 prep of,Significances
R14679 T21282 T21281 pobj differences,of
R14680 T21283 T21282 prep between,differences
R14681 T21284 T21285 amod experimental,data
R14682 T21285 T21283 pobj data,between
R14683 T21286 T21282 punct (,differences
R14684 T21287 T21282 prep for,differences
R14685 T21288 T21287 pobj example,for
R14686 T21289 T21290 nsubj GP,vs
R14687 T21290 T21315 ccomp vs,analysed
R14688 T21291 T21290 dobj LPS,vs
R14689 T21292 T21290 punct ),vs
R14690 T21293 T21295 advmod as,as
R14691 T21294 T21295 advmod well,as
R14692 T21295 T21290 cc as,vs
R14693 T21296 T21295 prep between,as
R14694 T21297 T21298 amod experimental,data
R14695 T21298 T21296 pobj data,between
R14696 T21299 T21298 cc and,data
R14697 T21300 T21301 amod theoretical,values
R14698 T21301 T21298 conj values,data
R14699 T21302 T21308 punct (,vs
R14700 T21303 T21308 prep for,vs
R14701 T21304 T21303 pobj example,for
R14702 T21305 T21307 compound GP,TSST-1
R14703 T21306 T21307 compound +,TSST-1
R14704 T21307 T21308 nsubj TSST-1,vs
R14705 T21308 T21290 parataxis vs,vs
R14706 T21309 T21311 nmod GP/TSST,calc
R14707 T21310 T21311 nummod -1,calc
R14708 T21311 T21308 dobj calc,vs
R14709 T21312 T21308 punct .,vs
R14710 T21313 T21315 punct ),analysed
R14711 T21314 T21315 auxpass were,analysed
R14712 T21315 T21315 ROOT analysed,analysed
R14713 T21316 T21315 advcl using,analysed
R14714 T21317 T21318 det the,Student
R14715 T21318 T21320 poss Student,t-test
R14716 T21319 T21318 case 's,Student
R14717 T21320 T21316 dobj t-test,using
R14718 T21321 T21320 punct (,t-test
R14719 T21322 T21323 amod normal,distribution
R14720 T21323 T21320 appos distribution,t-test
R14721 T21324 T21320 punct ),t-test
R14722 T21325 T21320 cc or,t-test
R14723 T21326 T21329 det the,test
R14724 T21327 T21328 compound Wilcoxon,Signed-Rank
R14725 T21328 T21329 compound Signed-Rank,test
R14726 T21329 T21320 conj test,t-test
R14727 T21330 T21332 punct (,distribution
R14728 T21331 T21332 amod non-normal,distribution
R14729 T21332 T21329 appos distribution,test
R14730 T21333 T21329 punct ),test
R14731 T21334 T21315 punct ",",analysed
R14732 T21335 T21336 punct (,SPSS
R14733 T21336 T21315 appos SPSS,analysed
R14734 T21337 T21336 prep for,SPSS
R14735 T21338 T21337 pobj Windows,for
R14736 T21339 T21336 punct ;,SPSS
R14737 T21340 T21342 compound SPSS,Software
R14738 T21341 T21342 compound Science,Software
R14739 T21342 T21336 npadvmod Software,SPSS
R14740 T21343 T21342 punct ",",Software
R14741 T21344 T21342 conj Erkrath,Software
R14742 T21345 T21344 punct ",",Erkrath
R14743 T21346 T21344 conj Germany,Erkrath
R14744 T21347 T21336 punct ),SPSS
R14745 T21348 T21315 punct .,analysed
R15037 T21926 T21929 advmod A,led
R15038 T21927 T21929 punct ",",led
R15039 T21928 T21929 nsubj GP,led
R15040 T21929 T21929 ROOT led,led
R15041 T21930 T21929 prep to,led
R15042 T21931 T21930 pobj DNA,to
R15043 T21932 T21929 advcl binding,led
R15044 T21933 T21932 prep of,binding
R15045 T21934 T21933 pobj NFAT,of
R15046 T21935 T21934 punct ",",NFAT
R15047 T21936 T21934 conj NFκB,NFAT
R15048 T21937 T21936 cc and,NFκB
R15049 T21938 T21936 conj NFIL-6,NFκB
R15050 T21939 T21929 punct .,led
R15051 T21940 T21941 compound Human,PBMC
R15052 T21941 T21943 nsubjpass PBMC,incubated
R15053 T21942 T21943 auxpass were,incubated
R15054 T21943 T21943 ROOT incubated,incubated
R15055 T21944 T21943 prep with,incubated
R15056 T21945 T21946 compound medium,control
R15057 T21946 T21944 pobj control,with
R15058 T21947 T21946 cc or,control
R15059 T21948 T21946 conj GP,control
R15060 T21949 T21950 punct (,1
R15061 T21950 T21948 nummod 1,GP
R15062 T21951 T21948 cc and,GP
R15063 T21952 T21953 nummod 100,μg
R15064 T21953 T21948 conj μg,GP
R15065 T21954 T21953 punct ),μg
R15066 T21955 T21943 prep for,incubated
R15067 T21956 T21957 nummod 1,h
R15068 T21957 T21955 pobj h,for
R15069 T21958 T21957 prep at,h
R15070 T21959 T21960 nummod 37,°
R15071 T21960 T21962 compound °,Nuclear
R15072 T21961 T21962 compound C.,Nuclear
R15073 T21962 T21963 compound Nuclear,extracts
R15074 T21963 T21958 pobj extracts,at
R15075 T21964 T21965 auxpass were,incubated
R15076 T21965 T21943 conj incubated,incubated
R15077 T21966 T21965 prep with,incubated
R15078 T21967 T21969 det a,NFAT
R15079 T21968 T21969 compound 32P-labeled,NFAT
R15080 T21969 T21966 pobj NFAT,with
R15081 T21970 T21969 punct ",",NFAT
R15082 T21971 T21969 conj NFκB,NFAT
R15083 T21972 T21971 punct ",",NFκB
R15084 T21973 T21971 conj NFIL-6,NFκB
R15085 T21974 T21973 cc or,NFIL-6
R15086 T21975 T21977 amod NFκB-IL-8,probe
R15087 T21976 T21977 compound oligonucleotide,probe
R15088 T21977 T21973 conj probe,NFIL-6
R15089 T21978 T21977 amod corresponding,probe
R15090 T21979 T21978 prep to,corresponding
R15091 T21980 T21981 det the,IFNγ
R15092 T21981 T21989 nmod IFNγ,promoters
R15093 T21982 T21981 punct ",",IFNγ
R15094 T21983 T21981 conj TNFα,IFNγ
R15095 T21984 T21983 punct ",",TNFα
R15096 T21985 T21983 conj IL-6,TNFα
R15097 T21986 T21985 cc and,IL-6
R15098 T21987 T21985 conj IL-8,IL-6
R15099 T21988 T21989 compound gene,promoters
R15100 T21989 T21979 pobj promoters,to
R15101 T21990 T21989 punct (,promoters
R15102 T21991 T21993 nmod Table,)
R15103 T21992 T21991 nummod 1,Table
R15104 T21993 T21989 punct ),promoters
R15105 T21994 T21943 punct .,incubated
R15106 T21995 T22000 nsubj Arrows,indicate
R15107 T21996 T21995 prep with,Arrows
R15108 T21997 T21999 det the,head
R15109 T21998 T21999 amod black,head
R15110 T21999 T21996 pobj head,with
R15111 T22000 T22000 ROOT indicate,indicate
R15112 T22001 T22002 amod migrational,location
R15113 T22002 T22000 dobj location,indicate
R15114 T22003 T22002 prep of,location
R15115 T22004 T22005 det the,NFAT-DNA
R15116 T22005 T22003 pobj NFAT-DNA,of
R15117 T22006 T22005 punct ",",NFAT-DNA
R15118 T22007 T22005 conj NFκB-DNA,NFAT-DNA
R15119 T22008 T22007 punct ",",NFκB-DNA
R15120 T22009 T22007 conj NFIL-6-DNA,NFκB-DNA
R15121 T22010 T22009 cc or,NFIL-6-DNA
R15122 T22011 T22009 conj NFκB-IL-8-DNA,NFIL-6-DNA
R15123 T22012 T22013 amod complex,compared
R15124 T22013 T22000 prep compared,indicate
R15125 T22014 T22013 prep to,compared
R15126 T22015 T22016 amod free,probe
R15127 T22016 T22014 pobj probe,to
R15128 T22017 T22016 punct (,probe
R15129 T22018 T22019 det no,shift
R15130 T22019 T22016 appos shift,probe
R15131 T22020 T22016 punct ),probe
R15132 T22021 T22000 punct .,indicate
R15133 T22022 T22027 nsubj Arrow,indicates
R15134 T22023 T22022 prep with,Arrow
R15135 T22024 T22026 det the,head
R15136 T22025 T22026 amod open,head
R15137 T22026 T22023 pobj head,with
R15138 T22027 T22027 ROOT indicates,indicates
R15139 T22028 T22029 det a,supershift
R15140 T22029 T22027 dobj supershift,indicates
R15141 T22030 T22029 prep of,supershift
R15142 T22031 T22030 pobj NFκB-IL-8-DNA-anti-p65,of
R15143 T22032 T22029 cc and,supershift
R15144 T22033 T22034 punct -,p50
R15145 T22034 T22029 conj p50,supershift
R15146 T22035 T22034 punct ",",p50
R15147 T22036 T22034 conj respectively,p50
R15148 T22037 T22027 punct .,indicates
R15149 T22038 T22039 det An,autoradiogram
R15150 T22039 T22045 nsubjpass autoradiogram,shown
R15151 T22040 T22039 prep from,autoradiogram
R15152 T22041 T22043 det a,experiment
R15153 T22042 T22043 compound representative,experiment
R15154 T22043 T22040 pobj experiment,from
R15155 T22044 T22045 auxpass is,shown
R15156 T22045 T22045 ROOT shown,shown
R15157 T22046 T22045 punct (,shown
R15158 T22047 T22049 advmod n,7
R15159 T22048 T22049 punct =,7
R15160 T22049 T22045 npadvmod 7,shown
R15161 T22050 T22049 punct ),7
R15162 T22051 T22045 punct .,shown
R15163 T22052 T22055 compound B,DNA
R15164 T22053 T22054 punct ",",Decreased
R15165 T22054 T22055 compound Decreased,DNA
R15166 T22055 T22064 nsubj DNA,compared
R15167 T22056 T22055 amod binding,DNA
R15168 T22057 T22056 prep of,binding
R15169 T22058 T22057 pobj NFκB,of
R15170 T22059 T22064 prep following,compared
R15171 T22060 T22062 compound GP,TSST-1
R15172 T22061 T22062 compound +,TSST-1
R15173 T22062 T22059 pobj TSST-1,following
R15174 T22063 T22064 punct ",",compared
R15175 T22064 T22064 ROOT compared,compared
R15176 T22065 T22064 prep to,compared
R15177 T22066 T22065 pobj TSST-1,to
R15178 T22067 T22066 punct ",",TSST-1
R15179 T22068 T22066 conj GP,TSST-1
R15180 T22069 T22068 punct ",",GP
R15181 T22070 T22068 cc or,GP
R15182 T22071 T22073 nummod TSST-1,GP
R15183 T22072 T22073 nummod /,GP
R15184 T22073 T22068 conj GP,GP
R15185 T22074 T22064 punct .,compared
R15186 T22075 T22076 compound Human,PBMC
R15187 T22076 T22078 nsubjpass PBMC,incubated
R15188 T22077 T22078 auxpass were,incubated
R15189 T22078 T22078 ROOT incubated,incubated
R15190 T22079 T22078 prep with,incubated
R15191 T22080 T22081 compound medium,control
R15192 T22081 T22079 pobj control,with
R15193 T22082 T22081 punct ",",control
R15194 T22083 T22081 conj LPS,control
R15195 T22084 T22083 punct ",",LPS
R15196 T22085 T22083 conj TSST-1,LPS
R15197 T22086 T22085 punct ",",TSST-1
R15198 T22087 T22085 conj GP,TSST-1
R15199 T22088 T22090 punct (,μg
R15200 T22089 T22090 nummod 100,μg
R15201 T22090 T22087 appos μg,GP
R15202 T22091 T22090 punct ),μg
R15203 T22092 T22087 punct ",",GP
R15204 T22093 T22095 compound GP,TSST-1
R15205 T22094 T22095 compound +,TSST-1
R15206 T22095 T22087 conj TSST-1,GP
R15207 T22096 T22095 cc and,TSST-1
R15208 T22097 T22099 compound GP,LPS
R15209 T22098 T22099 compound +,LPS
R15210 T22099 T22095 conj LPS,TSST-1
R15211 T22100 T22078 prep for,incubated
R15212 T22101 T22102 nummod 1,h
R15213 T22102 T22100 pobj h,for
R15214 T22103 T22102 prep at,h
R15215 T22104 T22105 nummod 37,°
R15216 T22105 T22106 nummod °,C
R15217 T22106 T22103 pobj C,at
R15218 T22107 T22078 punct .,incubated
R15219 T22108 T22109 det An,autoradiogram
R15220 T22109 T22115 nsubjpass autoradiogram,shown
R15221 T22110 T22109 prep from,autoradiogram
R15222 T22111 T22113 det a,experiment
R15223 T22112 T22113 compound representative,experiment
R15224 T22113 T22110 pobj experiment,from
R15225 T22114 T22115 auxpass is,shown
R15226 T22115 T22115 ROOT shown,shown
R15227 T22116 T22115 punct .,shown
R15228 T22117 T22118 amod Schematic,representation
R15229 T22118 T22118 ROOT representation,representation
R15230 T22119 T22118 prep of,representation
R15231 T22120 T22119 pobj NFκB-DNA,of
R15232 T22121 T22122 amod binding,activity
R15233 T22122 T22119 pobj activity,of
R15234 T22123 T22118 prep following,representation
R15235 T22124 T22123 dobj GP,following
R15236 T22125 T22126 punct (,1
R15237 T22126 T22124 nummod 1,GP
R15238 T22127 T22124 cc and,GP
R15239 T22128 T22129 nummod 100,μg
R15240 T22129 T22124 conj μg,GP
R15241 T22130 T22129 punct ),μg
R15242 T22131 T22129 cc or,μg
R15243 T22132 T22133 nummod TSST-1,treatment
R15244 T22133 T22129 conj treatment,μg
R15245 T22134 T22136 punct (,ng
R15246 T22135 T22136 nummod 250,ng
R15247 T22136 T22133 appos ng,treatment
R15248 T22137 T22136 punct ),ng
R15249 T22138 T22140 advmod as,as
R15250 T22139 T22140 advmod well,as
R15251 T22140 T22133 cc as,treatment
R15252 T22141 T22142 amod simultaneous,administration
R15253 T22142 T22133 conj administration,treatment
R15254 T22143 T22133 prep of,treatment
R15255 T22144 T22145 det both,compounds
R15256 T22145 T22143 pobj compounds,of
R15257 T22146 T22145 cc and,compounds
R15258 T22147 T22149 det the,value
R15259 T22148 T22149 amod theoretical,value
R15260 T22149 T22129 appos value,μg
R15261 T22150 T22149 punct (,value
R15262 T22151 T22153 quantmod GP/TSST,calc
R15263 T22152 T22153 nummod -1,calc
R15264 T22153 T22149 appos calc,value
R15265 T22154 T22149 punct .,value
R15266 T22155 T22129 punct ),μg
R15267 T22156 T22118 punct .,representation
R15268 T22157 T22159 compound Medium,levels
R15269 T22158 T22159 compound control,levels
R15270 T22159 T22161 nsubjpass levels,set
R15271 T22160 T22161 auxpass were,set
R15272 T22161 T22161 ROOT set,set
R15273 T22162 T22161 oprd equal,set
R15274 T22163 T22161 prep to,set
R15275 T22164 T22166 nummod 1,SEM
R15276 T22165 T22166 nummod ±,SEM
R15277 T22166 T22163 pobj SEM,to
R15278 T22167 T22166 cc and,SEM
R15279 T22168 T22166 conj significances,SEM
R15280 T22169 T22168 punct (,significances
R15281 T22170 T22172 punct *,p
R15282 T22171 T22172 punct =,p
R15283 T22172 T22168 appos p,significances
R15284 T22173 T22174 nmod <,0.05
R15285 T22174 T22172 npadvmod 0.05,p
R15286 T22175 T22168 punct ),significances
R15287 T22176 T22177 auxpass are,shown
R15288 T22177 T22161 conj shown,set
R15289 T22178 T22177 prep with,shown
R15290 T22179 T22178 pobj respect,with
R15291 T22180 T22179 prep to,respect
R15292 T22181 T22182 amod medium,control
R15293 T22182 T22180 pobj control,to
R15294 T22183 T22186 punct (,4
R15295 T22184 T22185 advmod n,=
R15296 T22185 T22186 punct =,4
R15297 T22186 T22177 parataxis 4,shown
R15298 T22187 T22186 punct ),4
R15299 T22188 T22161 punct .,set
R15469 T22641 T22646 nsubjpass NFκB,involved
R15470 T22642 T22641 nummod p65/p50,NFκB
R15471 T22643 T22641 cc and,NFκB
R15472 T22644 T22641 conj NFATc2/c1,NFκB
R15473 T22645 T22646 auxpass were,involved
R15474 T22646 T22646 ROOT involved,involved
R15475 T22647 T22646 prep in,involved
R15476 T22648 T22649 compound GP-induced,DNA
R15477 T22649 T22647 pobj DNA,in
R15478 T22650 T22646 oprd binding,involved
R15479 T22651 T22646 punct .,involved
R15480 T22652 T22678 prep In,performed
R15481 T22653 T22652 pobj order,In
R15482 T22654 T22655 aux to,determine
R15483 T22655 T22653 acl determine,order
R15484 T22656 T22665 mark whether,related
R15485 T22657 T22660 det the,proteins
R15486 T22658 T22660 nmod DNA,proteins
R15487 T22659 T22660 amod binding,proteins
R15488 T22660 T22665 nsubjpass proteins,related
R15489 T22661 T22660 acl activated,proteins
R15490 T22662 T22661 agent by,activated
R15491 T22663 T22662 pobj GP,by
R15492 T22664 T22665 auxpass were,related
R15493 T22665 T22655 ccomp related,determine
R15494 T22666 T22665 prep to,related
R15495 T22667 T22676 nmod NFκB,blot
R15496 T22668 T22667 cc and,NFκB
R15497 T22669 T22667 conj NFAT,NFκB
R15498 T22670 T22669 punct ",",NFAT
R15499 T22671 T22672 det an,immuno
R15500 T22672 T22676 amod immuno,blot
R15501 T22673 T22674 punct (,dot
R15502 T22674 T22672 appos dot,immuno
R15503 T22675 T22674 punct ),dot
R15504 T22676 T22678 nsubjpass blot,performed
R15505 T22677 T22678 auxpass was,performed
R15506 T22678 T22678 ROOT performed,performed
R15507 T22679 T22678 punct .,performed
R15508 T22680 T22681 det A,representative
R15509 T22681 T22681 ROOT representative,representative
R15510 T22682 T22684 amod dot,showing
R15511 T22683 T22684 compound blot,showing
R15512 T22684 T22681 acl showing,representative
R15513 T22685 T22684 dobj staining,showing
R15514 T22686 T22685 prep of,staining
R15515 T22687 T22690 amod negative,controls
R15516 T22688 T22687 cc and,negative
R15517 T22689 T22687 conj positive,negative
R15518 T22690 T22686 pobj controls,of
R15519 T22691 T22694 punct (,NFκB
R15520 T22692 T22693 amod recombinant,proteins
R15521 T22693 T22694 nsubj proteins,NFκB
R15522 T22694 T22685 parataxis NFκB,staining
R15523 T22695 T22694 punct p52,NFκB
R15524 T22696 T22694 punct ",",NFκB
R15525 T22697 T22694 amod c-rel,NFκB
R15526 T22698 T22694 punct ;,NFκB
R15527 T22699 T22700 amod nuclear,extracts
R15528 T22700 T22685 conj extracts,staining
R15529 T22701 T22700 prep of,extracts
R15530 T22702 T22704 amod PMA-treated,cells
R15531 T22703 T22704 compound Jurkat,cells
R15532 T22704 T22701 pobj cells,of
R15533 T22705 T22685 amod positive,staining
R15534 T22706 T22684 prep for,showing
R15535 T22707 T22706 pobj NFκB,for
R15536 T22708 T22707 nummod p50,NFκB
R15537 T22709 T22707 punct ",",NFκB
R15538 T22710 T22707 conj p65,NFκB
R15539 T22711 T22706 cc and,for
R15540 T22712 T22706 conj for,for
R15541 T22713 T22712 pobj NFATc1,for
R15542 T22714 T22713 punct ",",NFATc1
R15543 T22715 T22713 appos c2,NFATc1
R15544 T22716 T22713 punct ),NFATc1
R15545 T22717 T22684 prep in,showing
R15546 T22718 T22720 det the,panel
R15547 T22719 T22720 amod upper,panel
R15548 T22720 T22717 pobj panel,in
R15549 T22721 T22720 cc and,panel
R15550 T22722 T22720 conj staining,panel
R15551 T22723 T22722 prep of,staining
R15552 T22724 T22725 amod nuclear,extracts
R15553 T22725 T22723 pobj extracts,of
R15554 T22726 T22725 prep of,extracts
R15555 T22727 T22728 compound GP-treated,PBMC
R15556 T22728 T22726 pobj PBMC,of
R15557 T22729 T22747 punct (,shown
R15558 T22730 T22747 nsubjpass positive,shown
R15559 T22731 T22730 prep for,positive
R15560 T22732 T22731 pobj NFκB,for
R15561 T22733 T22732 nummod p65,NFκB
R15562 T22734 T22732 punct ",",NFκB
R15563 T22735 T22732 appos p50,NFκB
R15564 T22736 T22732 cc and,NFκB
R15565 T22737 T22732 conj NFAT,NFκB
R15566 T22738 T22737 nummod c2,NFAT
R15567 T22739 T22737 punct ",",NFAT
R15568 T22740 T22737 appos c1,NFAT
R15569 T22741 T22737 punct ),NFAT
R15570 T22742 T22730 prep in,positive
R15571 T22743 T22745 det the,panel
R15572 T22744 T22745 amod lower,panel
R15573 T22745 T22742 pobj panel,in
R15574 T22746 T22747 auxpass is,shown
R15575 T22747 T22747 ROOT shown,shown
R15576 T22748 T22747 punct (,shown
R15577 T22749 T22751 advmod n,3
R15578 T22750 T22751 punct =,3
R15579 T22751 T22747 oprd 3,shown
R15580 T22752 T22751 punct ),3
R15581 T22753 T22747 punct .,shown
R15949 T23447 T23451 nsubjpass A,down-regulated
R15950 T23448 T23450 punct ",",was
R15951 T23449 T23450 nsubj IL-1β,was
R15952 T23450 T23451 auxpass was,down-regulated
R15953 T23451 T23451 ROOT down-regulated,down-regulated
R15954 T23452 T23451 punct (,down-regulated
R15955 T23453 T23454 nummod 12,h
R15956 T23454 T23458 nmod h,following
R15957 T23455 T23456 nummod 24,h
R15958 T23456 T23454 appos h,h
R15959 T23457 T23454 punct ),h
R15960 T23458 T23451 prep following,down-regulated
R15961 T23459 T23461 compound GP,TSST-1
R15962 T23460 T23461 compound +,TSST-1
R15963 T23461 T23458 dobj TSST-1,following
R15964 T23462 T23463 advmod when,compared
R15965 T23463 T23458 advcl compared,following
R15966 T23464 T23463 prep to,compared
R15967 T23465 T23464 pobj TSST-1,to
R15968 T23466 T23451 punct .,down-regulated
R15969 T23467 T23468 compound Time,course
R15970 T23468 T23468 ROOT course,course
R15971 T23469 T23471 punct (,h
R15972 T23470 T23471 nummod 48,h
R15973 T23471 T23468 appos h,course
R15974 T23472 T23471 punct ),h
R15975 T23473 T23471 prep of,h
R15976 T23474 T23475 compound IL-1β,production
R15977 T23475 T23473 pobj production,of
R15978 T23476 T23475 punct (,production
R15979 T23477 T23475 appos pg/ml,production
R15980 T23478 T23475 punct ),production
R15981 T23479 T23471 prep by,h
R15982 T23480 T23481 compound human,PBMC
R15983 T23481 T23479 pobj PBMC,by
R15984 T23482 T23471 prep incubated,h
R15985 T23483 T23482 prep with,incubated
R15986 T23484 T23485 compound medium,control
R15987 T23485 T23483 pobj control,with
R15988 T23486 T23485 punct ",",control
R15989 T23487 T23488 nummod 100,μg
R15990 T23488 T23489 compound μg,GP
R15991 T23489 T23485 appos GP,control
R15992 T23490 T23489 punct ",",GP
R15993 T23491 T23493 nummod 250,TSST-1
R15994 T23492 T23493 compound ng,TSST-1
R15995 T23493 T23489 appos TSST-1,GP
R15996 T23494 T23493 punct ",",TSST-1
R15997 T23495 T23497 compound GP,TSST-1
R15998 T23496 T23497 compound +,TSST-1
R15999 T23497 T23493 appos TSST-1,TSST-1
R16000 T23498 T23497 punct ",",TSST-1
R16001 T23499 T23501 nummod 250,LPS
R16002 T23500 T23501 compound ng,LPS
R16003 T23501 T23497 conj LPS,TSST-1
R16004 T23502 T23501 cc and,LPS
R16005 T23503 T23505 compound GP,LPS
R16006 T23504 T23505 compound +,LPS
R16007 T23505 T23501 conj LPS,LPS
R16008 T23506 T23482 punct .,incubated
R16009 T23507 T23514 prep At,was
R16010 T23508 T23509 nummod 18,h
R16011 T23509 T23507 pobj h,At
R16012 T23510 T23509 cc and,h
R16013 T23511 T23512 nummod 24,h
R16014 T23512 T23514 npadvmod h,was
R16015 T23513 T23514 expl there,was
R16016 T23514 T23514 ROOT was,was
R16017 T23515 T23517 det a,reduction
R16018 T23516 T23517 amod marked,reduction
R16019 T23517 T23514 attr reduction,was
R16020 T23518 T23517 prep in,reduction
R16021 T23519 T23520 compound IL-1β,production
R16022 T23520 T23518 pobj production,in
R16023 T23521 T23517 prep following,reduction
R16024 T23522 T23524 compound GP,TSST-1
R16025 T23523 T23524 compound +,TSST-1
R16026 T23524 T23521 pobj TSST-1,following
R16027 T23525 T23526 advmod when,compared
R16028 T23526 T23514 advcl compared,was
R16029 T23527 T23526 prep to,compared
R16030 T23528 T23532 dep TSST-1,p
R16031 T23529 T23528 punct (,TSST-1
R16032 T23530 T23528 prep *,TSST-1
R16033 T23531 T23532 punct =,p
R16034 T23532 T23527 pobj p,to
R16035 T23533 T23534 nmod <,0.05
R16036 T23534 T23532 npadvmod 0.05,p
R16037 T23535 T23532 punct ),p
R16038 T23536 T23514 punct .,was
R16039 T23537 T23537 ROOT Graphs,Graphs
R16040 T23538 T23537 acl depicting,Graphs
R16041 T23539 T23541 det the,values
R16042 T23540 T23541 amod theoretical,values
R16043 T23541 T23538 dobj values,depicting
R16044 T23542 T23538 prep for,depicting
R16045 T23543 T23544 compound GP/LPS,calc
R16046 T23544 T23542 pobj calc,for
R16047 T23545 T23538 punct .,depicting
R16048 T23546 T23549 cc and,calc
R16049 T23547 T23549 nmod GP/TSST,calc
R16050 T23548 T23549 nummod -1,calc
R16051 T23549 T23549 ROOT calc,calc
R16052 T23550 T23549 punct .,calc
R16053 T23551 T23553 auxpass are,shown
R16054 T23552 T23553 advmod also,shown
R16055 T23553 T23553 ROOT shown,shown
R16056 T23554 T23553 punct .,shown
R16057 T23555 T23556 amod IL-1β,levels
R16058 T23556 T23561 nsubjpass levels,obtained
R16059 T23557 T23556 prep in,levels
R16060 T23558 T23559 det the,supernatnant
R16061 T23559 T23557 pobj supernatnant,in
R16062 T23560 T23561 auxpass were,obtained
R16063 T23561 T23561 ROOT obtained,obtained
R16064 T23562 T23561 agent by,obtained
R16065 T23563 T23562 pobj Elisa,by
R16066 T23564 T23561 cc and,obtained
R16067 T23565 T23566 auxpass are,shown
R16068 T23566 T23561 conj shown,obtained
R16069 T23567 T23566 prep as,shown
R16070 T23568 T23570 amod mean,SEM
R16071 T23569 T23570 compound ±,SEM
R16072 T23570 T23567 pobj SEM,as
R16073 T23571 T23570 punct (,SEM
R16074 T23572 T23574 nmod n,3
R16075 T23573 T23574 punct =,3
R16076 T23574 T23570 appos 3,SEM
R16077 T23575 T23574 punct ),3
R16078 T23576 T23561 punct .,obtained
R16079 T23577 T23581 advmod B,exaggerated
R16080 T23578 T23581 punct ",",exaggerated
R16081 T23579 T23581 nsubjpass IL-1RA,exaggerated
R16082 T23580 T23581 auxpass was,exaggerated
R16083 T23581 T23581 ROOT exaggerated,exaggerated
R16084 T23582 T23581 prep following,exaggerated
R16085 T23583 T23585 compound GP,TSST-1
R16086 T23584 T23585 compound +,TSST-1
R16087 T23585 T23582 pobj TSST-1,following
R16088 T23586 T23588 punct (,h
R16089 T23587 T23588 nummod 12,h
R16090 T23588 T23585 appos h,TSST-1
R16091 T23589 T23590 nummod 48,h
R16092 T23590 T23588 appos h,h
R16093 T23591 T23588 punct ),h
R16094 T23592 T23593 advmod when,compared
R16095 T23593 T23581 advcl compared,exaggerated
R16096 T23594 T23593 prep to,compared
R16097 T23595 T23594 pobj TSST-1,to
R16098 T23596 T23581 punct .,exaggerated
R16099 T23597 T23598 compound Time,course
R16100 T23598 T23612 nsubj course,incubated
R16101 T23599 T23598 punct (,course
R16102 T23600 T23601 nummod 48,h
R16103 T23601 T23598 appos h,course
R16104 T23602 T23601 punct ),h
R16105 T23603 T23601 prep of,h
R16106 T23604 T23605 compound IL-1RA,production
R16107 T23605 T23603 pobj production,of
R16108 T23606 T23605 punct (,production
R16109 T23607 T23605 appos pg/ml,production
R16110 T23608 T23605 punct ),production
R16111 T23609 T23601 prep by,h
R16112 T23610 T23611 compound human,PBMC
R16113 T23611 T23609 pobj PBMC,by
R16114 T23612 T23612 ROOT incubated,incubated
R16115 T23613 T23612 prep with,incubated
R16116 T23614 T23615 compound medium,control
R16117 T23615 T23613 pobj control,with
R16118 T23616 T23615 punct ",",control
R16119 T23617 T23618 nummod 100,μg
R16120 T23618 T23619 compound μg,GP
R16121 T23619 T23615 appos GP,control
R16122 T23620 T23619 punct ",",GP
R16123 T23621 T23623 nummod 250,TSST-1
R16124 T23622 T23623 compound ng,TSST-1
R16125 T23623 T23619 appos TSST-1,GP
R16126 T23624 T23623 punct ",",TSST-1
R16127 T23625 T23627 compound GP,TSST-1
R16128 T23626 T23627 compound +,TSST-1
R16129 T23627 T23623 appos TSST-1,TSST-1
R16130 T23628 T23627 punct ",",TSST-1
R16131 T23629 T23631 nummod 250,LPS
R16132 T23630 T23631 compound ng,LPS
R16133 T23631 T23627 conj LPS,TSST-1
R16134 T23632 T23631 cc and,LPS
R16135 T23633 T23635 compound GP,LPS
R16136 T23634 T23635 compound +,LPS
R16137 T23635 T23631 conj LPS,LPS
R16138 T23636 T23612 punct .,incubated
R16139 T23637 T23642 mark Between,h
R16140 T23638 T23642 nsubj 18,h
R16141 T23639 T23638 quantmod h,18
R16142 T23640 T23638 cc and,18
R16143 T23641 T23638 conj 48,18
R16144 T23642 T23642 ROOT h,h
R16145 T23643 T23645 det a,treatment
R16146 T23644 T23645 amod simultaneous,treatment
R16147 T23645 T23652 nsubj treatment,led
R16148 T23646 T23645 prep of,treatment
R16149 T23647 T23646 pobj PBMC,of
R16150 T23648 T23645 prep with,treatment
R16151 T23649 T23651 compound GP,TSST-1
R16152 T23650 T23651 compound +,TSST-1
R16153 T23651 T23648 pobj TSST-1,with
R16154 T23652 T23642 ccomp led,h
R16155 T23653 T23652 prep to,led
R16156 T23654 T23656 det a,effect
R16157 T23655 T23656 amod synergistic,effect
R16158 T23656 T23653 pobj effect,to
R16159 T23657 T23652 punct ",",led
R16160 T23658 T23662 advmod i.e.,production
R16161 T23659 T23662 det a,production
R16162 T23660 T23662 amod higher,production
R16163 T23661 T23662 compound IL-1RA,production
R16164 T23662 T23652 advcl production,led
R16165 T23663 T23664 advmod when,compared
R16166 T23664 T23662 advcl compared,production
R16167 T23665 T23664 prep to,compared
R16168 T23666 T23667 det an,addition
R16169 T23667 T23665 pobj addition,to
R16170 T23668 T23667 prep of,addition
R16171 T23669 T23671 det the,values
R16172 T23670 T23671 amod single,values
R16173 T23671 T23668 pobj values,of
R16174 T23672 T23671 prep for,values
R16175 T23673 T23672 pobj TSST-1,for
R16176 T23674 T23671 cc and,values
R16177 T23675 T23671 conj GP,values
R16178 T23676 T23679 punct (,p
R16179 T23677 T23679 punct *,p
R16180 T23678 T23679 punct =,p
R16181 T23679 T23675 parataxis p,GP
R16182 T23680 T23681 nmod <,0.05
R16183 T23681 T23679 npadvmod 0.05,p
R16184 T23682 T23679 punct ),p
R16185 T23683 T23679 punct .,p
R16186 T23684 T23684 ROOT Graphs,Graphs
R16187 T23685 T23684 acl depicting,Graphs
R16188 T23686 T23688 det the,values
R16189 T23687 T23688 amod theoretical,values
R16190 T23688 T23685 dobj values,depicting
R16191 T23689 T23685 prep for,depicting
R16192 T23690 T23691 compound GP/LPS,calc
R16193 T23691 T23689 pobj calc,for
R16194 T23692 T23685 punct .,depicting
R16195 T23693 T23696 cc and,calc
R16196 T23694 T23694 ROOT GP/TSST,GP/TSST
R16197 T23695 T23696 nummod -1,calc
R16198 T23696 T23696 ROOT calc,calc
R16199 T23697 T23696 punct .,calc
R16200 T23698 T23699 auxpass are,included
R16201 T23699 T23699 ROOT included,included
R16202 T23700 T23699 punct .,included
R16203 T23701 T23702 compound IL-1RA,levels
R16204 T23702 T23707 nsubjpass levels,obtained
R16205 T23703 T23702 prep in,levels
R16206 T23704 T23705 det the,supernatnant
R16207 T23705 T23703 pobj supernatnant,in
R16208 T23706 T23707 auxpass were,obtained
R16209 T23707 T23707 ROOT obtained,obtained
R16210 T23708 T23707 agent by,obtained
R16211 T23709 T23708 pobj Elisa,by
R16212 T23710 T23707 cc and,obtained
R16213 T23711 T23712 auxpass are,shown
R16214 T23712 T23707 conj shown,obtained
R16215 T23713 T23712 prep as,shown
R16216 T23714 T23716 amod mean,SEM
R16217 T23715 T23716 compound ±,SEM
R16218 T23716 T23713 pobj SEM,as
R16219 T23717 T23716 punct (,SEM
R16220 T23718 T23720 advmod n,3
R16221 T23719 T23720 punct =,3
R16222 T23720 T23716 prep 3,SEM
R16223 T23721 T23720 punct ),3
R16224 T23722 T23707 punct .,obtained
R16352 T24021 T24022 nsubj GP,modulated
R16353 T24022 T24022 ROOT modulated,modulated
R16354 T24023 T24022 dobj LPS,modulated
R16355 T24024 T24023 punct -,LPS
R16356 T24025 T24023 cc and,LPS
R16357 T24026 T24027 amod TSST-1-induced,binding
R16358 T24027 T24022 oprd binding,modulated
R16359 T24028 T24022 prep to,modulated
R16360 T24029 T24032 det a,site
R16361 T24030 T24032 amod new,site
R16362 T24031 T24032 amod NFκB3,site
R16363 T24032 T24028 pobj site,to
R16364 T24033 T24032 prep in,site
R16365 T24034 T24036 det the,promoter
R16366 T24035 T24036 compound IL-1RA,promoter
R16367 T24036 T24033 pobj promoter,in
R16368 T24037 T24022 punct .,modulated
R16369 T24038 T24040 nsubjpass Binding,enhanced
R16370 T24039 T24040 auxpass was,enhanced
R16371 T24040 T24040 ROOT enhanced,enhanced
R16372 T24041 T24040 prep for,enhanced
R16373 T24042 T24044 compound GP,LPS
R16374 T24043 T24044 compound +,LPS
R16375 T24044 T24041 pobj LPS,for
R16376 T24045 T24044 cc and,LPS
R16377 T24046 T24048 compound GP,TSST-1
R16378 T24047 T24048 compound +,TSST-1
R16379 T24048 T24044 conj TSST-1,LPS
R16380 T24049 T24040 punct ",",enhanced
R16381 T24050 T24051 advmod when,compared
R16382 T24051 T24040 advcl compared,enhanced
R16383 T24052 T24051 prep to,compared
R16384 T24053 T24052 pobj LPS,to
R16385 T24054 T24053 punct ",",LPS
R16386 T24055 T24053 conj TSST-1,LPS
R16387 T24056 T24055 punct ",",TSST-1
R16388 T24057 T24055 conj GP,TSST-1
R16389 T24058 T24057 punct ",",GP
R16390 T24059 T24060 compound GP/LPS,calc
R16391 T24060 T24057 appos calc,GP
R16392 T24061 T24060 punct .,calc
R16393 T24062 T24057 cc or,GP
R16394 T24063 T24057 conj GP/TSST,GP
R16395 T24064 T24065 nummod -1,calc.
R16396 T24065 T24067 npadvmod calc.,respectively
R16397 T24066 T24065 punct ",",calc.
R16398 T24067 T24040 advmod respectively,enhanced
R16399 T24068 T24077 punct (,p
R16400 T24069 T24077 punct *,p
R16401 T24070 T24077 punct =,p
R16402 T24071 T24077 ccomp p,p
R16403 T24072 T24073 nmod <,0.05
R16404 T24073 T24071 npadvmod 0.05,p
R16405 T24074 T24077 punct ;,p
R16406 T24075 T24077 punct **,p
R16407 T24076 T24077 punct =,p
R16408 T24077 T24040 parataxis p,enhanced
R16409 T24078 T24079 nmod <,0.01
R16410 T24079 T24077 npadvmod 0.01,p
R16411 T24080 T24077 punct ),p
R16412 T24081 T24040 punct .,enhanced
R16413 T24082 T24084 compound Medium,levels
R16414 T24083 T24084 compound control,levels
R16415 T24084 T24086 nsubjpass levels,set
R16416 T24085 T24086 auxpass were,set
R16417 T24086 T24086 ROOT set,set
R16418 T24087 T24086 oprd equal,set
R16419 T24088 T24086 prep to,set
R16420 T24089 T24091 nummod 1,SEM
R16421 T24090 T24091 nummod ±,SEM
R16422 T24091 T24088 pobj SEM,to
R16423 T24092 T24095 punct (,6
R16424 T24093 T24095 advmod n,6
R16425 T24094 T24095 punct =,6
R16426 T24095 T24091 appos 6,SEM
R16427 T24096 T24095 punct ),6
R16428 T24097 T24086 punct .,set
R16429 T24098 T24099 compound DNA,binding
R16430 T24099 T24101 nsubjpass binding,assessed
R16431 T24100 T24101 auxpass was,assessed
R16432 T24101 T24101 ROOT assessed,assessed
R16433 T24102 T24101 agent by,assessed
R16434 T24103 T24102 pobj EMSA,by
R16435 T24104 T24105 punct (,see
R16436 T24105 T24101 parataxis see,assessed
R16437 T24106 T24105 dobj methods,see
R16438 T24107 T24105 punct ),see
R16439 T24108 T24101 punct .,assessed
R16668 T24494 T24495 nsubj GP,modulated
R16669 T24495 T24495 ROOT modulated,modulated
R16670 T24496 T24497 compound TSST-1-induced,DNA
R16671 T24497 T24495 dobj DNA,modulated
R16672 T24498 T24495 advcl binding,modulated
R16673 T24499 T24498 prep to,binding
R16674 T24500 T24503 det a,site
R16675 T24501 T24503 amod new,site
R16676 T24502 T24503 compound NFATP2/3,site
R16677 T24503 T24499 pobj site,to
R16678 T24504 T24503 prep in,site
R16679 T24505 T24507 det the,promoter
R16680 T24506 T24507 compound IL-1RA,promoter
R16681 T24507 T24504 pobj promoter,in
R16682 T24508 T24495 punct .,modulated
R16683 T24509 T24510 nsubj Binding,was
R16684 T24510 T24510 ROOT was,was
R16685 T24511 T24510 acomp up-regulated,was
R16686 T24512 T24511 prep for,up-regulated
R16687 T24513 T24515 compound GP,LPS
R16688 T24514 T24515 compound +,LPS
R16689 T24515 T24512 pobj LPS,for
R16690 T24516 T24515 cc and,LPS
R16691 T24517 T24519 compound GP,TSST-1
R16692 T24518 T24519 compound +,TSST-1
R16693 T24519 T24515 conj TSST-1,LPS
R16694 T24520 T24510 punct ",",was
R16695 T24521 T24522 advmod when,compared
R16696 T24522 T24510 advcl compared,was
R16697 T24523 T24522 prep to,compared
R16698 T24524 T24523 pobj GP,to
R16699 T24525 T24524 cc and,GP
R16700 T24526 T24524 punct ",",GP
R16701 T24527 T24524 prep in,GP
R16702 T24528 T24530 det the,case
R16703 T24529 T24530 amod latter,case
R16704 T24530 T24527 pobj case,in
R16705 T24531 T24510 punct ",",was
R16706 T24532 T24540 prep to,p
R16707 T24533 T24534 preconj both,GP
R16708 T24534 T24532 pobj GP,to
R16709 T24535 T24534 cc and,GP
R16710 T24536 T24534 conj TSST-1,GP
R16711 T24537 T24540 punct (,p
R16712 T24538 T24540 punct *,p
R16713 T24539 T24540 punct =,p
R16714 T24540 T24510 advcl p,was
R16715 T24541 T24542 nmod <,0.05
R16716 T24542 T24540 npadvmod 0.05,p
R16717 T24543 T24540 punct ),p
R16718 T24544 T24510 punct .,was
R16719 T24545 T24546 compound Human,PBMC
R16720 T24546 T24548 nsubjpass PBMC,incubated
R16721 T24547 T24548 auxpass were,incubated
R16722 T24548 T24548 ROOT incubated,incubated
R16723 T24549 T24548 prep with,incubated
R16724 T24550 T24551 compound medium,control
R16725 T24551 T24549 pobj control,with
R16726 T24552 T24551 punct ",",control
R16727 T24553 T24551 conj LPS,control
R16728 T24554 T24553 punct ",",LPS
R16729 T24555 T24553 conj TSST-1,LPS
R16730 T24556 T24555 punct ",",TSST-1
R16731 T24557 T24555 conj GP,TSST-1
R16732 T24558 T24557 punct ",",GP
R16733 T24559 T24561 compound GP,TSST-1
R16734 T24560 T24561 compound +,TSST-1
R16735 T24561 T24557 conj TSST-1,GP
R16736 T24562 T24561 cc and,TSST-1
R16737 T24563 T24565 compound GP,LPS
R16738 T24564 T24565 compound +,LPS
R16739 T24565 T24561 conj LPS,TSST-1
R16740 T24566 T24548 prep for,incubated
R16741 T24567 T24568 nummod 1,h
R16742 T24568 T24566 pobj h,for
R16743 T24569 T24568 prep at,h
R16744 T24570 T24571 nummod 37,°
R16745 T24571 T24574 nummod °,representation
R16746 T24572 T24573 compound C.,Schematic
R16747 T24573 T24574 compound Schematic,representation
R16748 T24574 T24569 pobj representation,at
R16749 T24575 T24574 prep of,representation
R16750 T24576 T24580 det the,activity
R16751 T24577 T24580 amod elevated,activity
R16752 T24578 T24580 nmod NFAT-DNA,activity
R16753 T24579 T24580 amod binding,activity
R16754 T24580 T24575 pobj activity,of
R16755 T24581 T24580 prep to,activity
R16756 T24582 T24583 det the,site
R16757 T24583 T24581 pobj site,to
R16758 T24584 T24583 prep in,site
R16759 T24585 T24587 det the,promoter
R16760 T24586 T24587 compound IL-1RA,promoter
R16761 T24587 T24584 pobj promoter,in
R16762 T24588 T24548 punct .,incubated
R16763 T24589 T24589 ROOT Bars,Bars
R16764 T24590 T24589 acl depicting,Bars
R16765 T24591 T24593 det the,values
R16766 T24592 T24593 amod theoretical,values
R16767 T24593 T24590 dobj values,depicting
R16768 T24594 T24593 prep for,values
R16769 T24595 T24596 compound GP/LPS,calc
R16770 T24596 T24594 pobj calc,for
R16771 T24597 T24590 punct .,depicting
R16772 T24598 T24601 cc and,calc
R16773 T24599 T24601 nmod GP/TSST,calc
R16774 T24600 T24601 nummod -1,calc
R16775 T24601 T24601 ROOT calc,calc
R16776 T24602 T24601 punct .,calc
R16777 T24603 T24604 auxpass are,added
R16778 T24604 T24604 ROOT added,added
R16779 T24605 T24604 punct .,added
R16780 T24606 T24608 compound Medium,levels
R16781 T24607 T24608 compound control,levels
R16782 T24608 T24610 nsubjpass levels,set
R16783 T24609 T24610 auxpass were,set
R16784 T24610 T24610 ROOT set,set
R16785 T24611 T24610 oprd equal,set
R16786 T24612 T24610 prep to,set
R16787 T24613 T24615 nummod 1,SEM
R16788 T24614 T24615 nummod ±,SEM
R16789 T24615 T24612 pobj SEM,to
R16790 T24616 T24619 punct (,6
R16791 T24617 T24619 advmod n,6
R16792 T24618 T24619 punct =,6
R16793 T24619 T24615 appos 6,SEM
R16794 T24620 T24610 punct ),set
R16795 T24621 T24610 punct .,set
R16796 T24622 T24623 det An,autoradiogram
R16797 T24623 T24629 nsubjpass autoradiogram,shown
R16798 T24624 T24623 prep of,autoradiogram
R16799 T24625 T24627 det a,experiment
R16800 T24626 T24627 compound representative,experiment
R16801 T24627 T24624 pobj experiment,of
R16802 T24628 T24629 auxpass is,shown
R16803 T24629 T24651 ccomp shown,lane
R16804 T24630 T24629 prep in,shown
R16805 T24631 T24633 det the,panel
R16806 T24632 T24633 amod lower,panel
R16807 T24633 T24630 pobj panel,in
R16808 T24634 T24633 punct (,panel
R16809 T24635 T24633 appos lane,panel
R16810 T24636 T24635 nummod 1,lane
R16811 T24637 T24633 punct :,panel
R16812 T24638 T24633 appos water,panel
R16813 T24639 T24651 punct ;,lane
R16814 T24640 T24651 compound lane,lane
R16815 T24641 T24640 nummod 2,lane
R16816 T24642 T24640 punct :,lane
R16817 T24643 T24644 compound medium,control
R16818 T24644 T24640 appos control,lane
R16819 T24645 T24640 punct ;,lane
R16820 T24646 T24640 appos lane,lane
R16821 T24647 T24646 nummod 3,lane
R16822 T24648 T24646 punct :,lane
R16823 T24649 T24646 appos GP,lane
R16824 T24650 T24640 punct ;,lane
R16825 T24651 T24651 ROOT lane,lane
R16826 T24652 T24651 nummod 4,lane
R16827 T24653 T24651 punct :,lane
R16828 T24654 T24651 appos LPS,lane
R16829 T24655 T24651 punct ;,lane
R16830 T24656 T24651 appos lane,lane
R16831 T24657 T24656 nummod 5,lane
R16832 T24658 T24656 punct :,lane
R16833 T24659 T24656 appos TSST-1,lane
R16834 T24660 T24659 punct ",",TSST-1
R16835 T24661 T24651 appos lane,lane
R16836 T24662 T24661 nummod 6,lane
R16837 T24663 T24661 punct :,lane
R16838 T24664 T24666 compound GP,LPS
R16839 T24665 T24666 compound +,LPS
R16840 T24666 T24661 appos LPS,lane
R16841 T24667 T24661 punct ;,lane
R16842 T24668 T24651 appos lane,lane
R16843 T24669 T24668 nummod 7,lane
R16844 T24670 T24651 punct :,lane
R16845 T24671 T24673 compound GP,TSST-1
R16846 T24672 T24673 compound +,TSST-1
R16847 T24673 T24651 appos TSST-1,lane
R16848 T24674 T24651 punct ),lane
R16849 T24675 T24651 punct .,lane
R17056 T25158 T25162 amod Decreased,ratio
R17057 T25159 T25162 amod IL-1β,ratio
R17058 T25160 T25162 nmod /,ratio
R17059 T25161 T25162 compound IL-1RA,ratio
R17060 T25162 T25162 ROOT ratio,ratio
R17061 T25163 T25162 acl following,ratio
R17062 T25164 T25166 compound GP,TSST-1
R17063 T25165 T25166 compound +,TSST-1
R17064 T25166 T25163 pobj TSST-1,following
R17065 T25167 T25168 advmod when,compared
R17066 T25168 T25162 advcl compared,ratio
R17067 T25169 T25168 prep to,compared
R17068 T25170 T25169 pobj TSST-1,to
R17069 T25171 T25162 punct .,ratio
R17070 T25172 T25173 compound Time,course
R17071 T25173 T25173 ROOT course,course
R17072 T25174 T25173 punct (,course
R17073 T25175 T25176 nummod 48,h
R17074 T25176 T25173 appos h,course
R17075 T25177 T25176 punct ),h
R17076 T25178 T25176 prep of,h
R17077 T25179 T25183 det the,ratio
R17078 T25180 T25183 amod IL-1β,ratio
R17079 T25181 T25183 nmod /,ratio
R17080 T25182 T25183 compound IL-1RA,ratio
R17081 T25183 T25178 pobj ratio,of
R17082 T25184 T25183 acl following,ratio
R17083 T25185 T25184 pobj incubation,following
R17084 T25186 T25185 prep of,incubation
R17085 T25187 T25188 amod human,PBMC
R17086 T25188 T25186 pobj PBMC,of
R17087 T25189 T25185 prep with,incubation
R17088 T25190 T25189 pobj LPS,with
R17089 T25191 T25190 punct ",",LPS
R17090 T25192 T25190 conj TSST-1,LPS
R17091 T25193 T25192 punct ",",TSST-1
R17092 T25194 T25196 compound GP,LPS
R17093 T25195 T25196 compound +,LPS
R17094 T25196 T25192 conj LPS,TSST-1
R17095 T25197 T25196 punct ",",LPS
R17096 T25198 T25199 compound GP/LPS,calc.
R17097 T25199 T25196 conj calc.,LPS
R17098 T25200 T25199 punct ",",calc.
R17099 T25201 T25203 compound GP,TSST-1
R17100 T25202 T25203 compound +,TSST-1
R17101 T25203 T25199 conj TSST-1,calc.
R17102 T25204 T25203 cc or,TSST-1
R17103 T25205 T25203 conj GP/TSST,TSST-1
R17104 T25206 T25207 nummod -1,calc
R17105 T25207 T25203 conj calc,TSST-1
R17106 T25208 T25173 punct .,course
R17107 T25209 T25214 nmod LPS,treatments
R17108 T25210 T25209 cc and,LPS
R17109 T25211 T25213 compound GP,LPS
R17110 T25212 T25213 compound +,LPS
R17111 T25213 T25209 conj LPS,LPS
R17112 T25214 T25215 nsubj treatments,resulted
R17113 T25215 T25215 ROOT resulted,resulted
R17114 T25216 T25215 prep in,resulted
R17115 T25217 T25216 pcomp generating,in
R17116 T25218 T25219 advmod more,IL-1β
R17117 T25219 T25217 dobj IL-1β,generating
R17118 T25220 T25219 prep than,IL-1β
R17119 T25221 T25220 pobj IL-1RA,than
R17120 T25222 T25224 quantmod up,24
R17121 T25223 T25224 quantmod to,24
R17122 T25224 T25225 nummod 24,h
R17123 T25225 T25217 npadvmod h,generating
R17124 T25226 T25215 punct .,resulted
R17125 T25227 T25228 advmod When,comparing
R17126 T25228 T25228 ROOT comparing,comparing
R17127 T25229 T25228 dobj LPS,comparing
R17128 T25230 T25229 cc or,LPS
R17129 T25231 T25232 compound GP/LPS,calc
R17130 T25232 T25229 conj calc,LPS
R17131 T25233 T25228 punct .,comparing
R17132 T25234 T25241 dep vs,find
R17133 T25235 T25241 dep GP,find
R17134 T25236 T25237 det +,LPS
R17135 T25237 T25235 appos LPS,GP
R17136 T25238 T25241 nsubj we,find
R17137 T25239 T25241 aux did,find
R17138 T25240 T25241 neg not,find
R17139 T25241 T25241 ROOT find,find
R17140 T25242 T25243 amod significant,alterations
R17141 T25243 T25241 dobj alterations,find
R17142 T25244 T25243 prep in,alterations
R17143 T25245 T25249 det the,ratio
R17144 T25246 T25249 amod IL-1β,ratio
R17145 T25247 T25249 nmod /,ratio
R17146 T25248 T25249 compound IL-1RA,ratio
R17147 T25249 T25244 pobj ratio,in
R17148 T25250 T25249 prep over,ratio
R17149 T25251 T25250 pobj 48,over
R17150 T25252 T25250 pobj h.,over
R17151 T25253 T25253 ROOT With,With
R17152 T25254 T25253 pobj respect,With
R17153 T25255 T25254 prep to,respect
R17154 T25256 T25255 pobj TSST-1,to
R17155 T25257 T25256 cc or,TSST-1
R17156 T25258 T25260 nmod GP/TSST,calc
R17157 T25259 T25260 nummod -1,calc
R17158 T25260 T25256 conj calc,TSST-1
R17159 T25261 T25260 punct .,calc
R17160 T25262 T25265 nmod vs,TSST-1
R17161 T25263 T25265 nmod GP,TSST-1
R17162 T25264 T25265 nmod +,TSST-1
R17163 T25265 T25265 ROOT TSST-1,TSST-1
R17164 T25266 T25267 nsubj we,observed
R17165 T25267 T25267 ROOT observed,observed
R17166 T25268 T25271 det a,action
R17167 T25269 T25271 amod pronounced,action
R17168 T25270 T25271 amod anti-inflammatory,action
R17169 T25271 T25267 dobj action,observed
R17170 T25272 T25271 prep of,action
R17171 T25273 T25272 pobj GP,of
R17172 T25274 T25267 punct ",",observed
R17173 T25275 T25276 mark as,demonstrated
R17174 T25276 T25267 advcl demonstrated,observed
R17175 T25277 T25276 agent by,demonstrated
R17176 T25278 T25280 det an,10
R17177 T25279 T25280 quantmod about,10
R17178 T25280 T25277 pobj 10,by
R17179 T25281 T25282 nummod 100,fold
R17180 T25282 T25280 appos fold,10
R17181 T25283 T25284 amod reduced,ratio
R17182 T25284 T25282 dobj ratio,fold
R17183 T25285 T25282 prep at,fold
R17184 T25286 T25287 nummod 18,h
R17185 T25287 T25285 pobj h,at
R17186 T25288 T25287 cc and,h
R17187 T25289 T25290 nummod 24,h
R17188 T25290 T25287 conj h,h
R17189 T25291 T25290 punct ",",h
R17190 T25292 T25295 advmod i.e.,production
R17191 T25293 T25295 det a,production
R17192 T25294 T25295 amod higher,production
R17193 T25295 T25290 appos production,h
R17194 T25296 T25295 prep of,production
R17195 T25297 T25296 pobj IL-1RA,of
R17196 T25298 T25295 prep than,production
R17197 T25299 T25298 prep of,than
R17198 T25300 T25299 pobj IL-1β,of
R17199 T25301 T25304 punct (,p
R17200 T25302 T25304 punct *,p
R17201 T25303 T25304 punct =,p
R17202 T25304 T25290 appos p,h
R17203 T25305 T25306 nmod <,0.05
R17204 T25306 T25304 npadvmod 0.05,p
R17205 T25307 T25304 punct ),p
R17206 T25308 T25267 punct .,observed
R17207 T25309 T25311 nsubjpass Data,shown
R17208 T25310 T25311 auxpass are,shown
R17209 T25311 T25311 ROOT shown,shown
R17210 T25312 T25311 prep as,shown
R17211 T25313 T25315 amod mean,SEM
R17212 T25314 T25315 compound ±,SEM
R17213 T25315 T25312 pobj SEM,as
R17214 T25316 T25315 punct (,SEM
R17215 T25317 T25319 nmod n,3
R17216 T25318 T25319 punct =,3
R17217 T25319 T25315 prep 3,SEM
R17218 T25320 T25319 punct ),3
R17219 T25321 T25311 punct .,shown
R17571 T25858 T25858 ROOT Inhibition,Inhibition
R17572 T25859 T25858 prep of,Inhibition
R17573 T25860 T25861 compound GP-induced,NFκB
R17574 T25861 T25859 pobj NFκB,of
R17575 T25862 T25861 punct ",",NFκB
R17576 T25863 T25861 conj NFAT,NFκB
R17577 T25864 T25863 cc and,NFAT
R17578 T25865 T25866 compound NFIL-6,DNA
R17579 T25866 T25863 conj DNA,NFAT
R17580 T25867 T25858 conj binding,Inhibition
R17581 T25868 T25867 prep to,binding
R17582 T25869 T25871 det the,promoter
R17583 T25870 T25871 compound IL-1RA,promoter
R17584 T25871 T25868 pobj promoter,to
R17585 T25872 T25858 punct .,Inhibition
R17586 T25873 T25957 nsubjpass A,displayed
R17587 T25874 T25873 punct ",",A
R17588 T25875 T25877 det A,autoradiogram
R17589 T25876 T25877 amod representative,autoradiogram
R17590 T25877 T25889 nsubj autoradiogram,lane
R17591 T25878 T25877 punct (,autoradiogram
R17592 T25879 T25877 appos lane,autoradiogram
R17593 T25880 T25879 nummod 1,lane
R17594 T25881 T25879 punct :,lane
R17595 T25882 T25879 appos control,lane
R17596 T25883 T25882 punct ",",control
R17597 T25884 T25877 parataxis lane,autoradiogram
R17598 T25885 T25884 nummod 2,lane
R17599 T25886 T25884 punct :,lane
R17600 T25887 T25884 appos GP,lane
R17601 T25888 T25887 punct ",",GP
R17602 T25889 T25873 appos lane,A
R17603 T25890 T25889 nummod 3,lane
R17604 T25891 T25889 punct :,lane
R17605 T25892 T25895 nsubj GP,mutated
R17606 T25893 T25895 npadvmod +,mutated
R17607 T25894 T25895 nsubj unlabeled,mutated
R17608 T25895 T25899 amod mutated,lane
R17609 T25896 T25897 nummod NFATP2/3,oligo
R17610 T25897 T25895 dobj oligo,mutated
R17611 T25898 T25897 punct ",",oligo
R17612 T25899 T25913 compound lane,lane
R17613 T25900 T25899 nummod 4,lane
R17614 T25901 T25899 punct :,lane
R17615 T25902 T25904 compound GP,CAPE
R17616 T25903 T25904 compound +,CAPE
R17617 T25904 T25899 appos CAPE,lane
R17618 T25905 T25904 punct ",",CAPE
R17619 T25906 T25899 conj lane,lane
R17620 T25907 T25906 nummod 5,lane
R17621 T25908 T25899 punct :,lane
R17622 T25909 T25911 compound GP,CyA
R17623 T25910 T25911 compound +,CyA
R17624 T25911 T25899 appos CyA,lane
R17625 T25912 T25911 punct ",",CyA
R17626 T25913 T25929 compound lane,lane
R17627 T25914 T25913 nummod 6,lane
R17628 T25915 T25913 punct :,lane
R17629 T25916 T25918 compound GP,CHX
R17630 T25917 T25918 compound +,CHX
R17631 T25918 T25913 appos CHX,lane
R17632 T25919 T25918 punct ",",CHX
R17633 T25920 T25913 parataxis lane,lane
R17634 T25921 T25920 nummod 7,lane
R17635 T25922 T25913 punct :,lane
R17636 T25923 T25924 nmod GP,+
R17637 T25924 T25927 nmod +,oligo
R17638 T25925 T25927 amod unlabeled,oligo
R17639 T25926 T25927 compound NFATP2/3,oligo
R17640 T25927 T25913 appos oligo,lane
R17641 T25928 T25927 punct ",",oligo
R17642 T25929 T25873 appos lane,A
R17643 T25930 T25929 nummod 8,lane
R17644 T25931 T25929 punct :,lane
R17645 T25932 T25929 appos water,lane
R17646 T25933 T25929 punct ),lane
R17647 T25934 T25936 advmod as,as
R17648 T25935 T25936 advmod well,as
R17649 T25936 T25929 cc as,lane
R17650 T25937 T25939 det a,summary
R17651 T25938 T25939 amod graphical,summary
R17652 T25939 T25929 conj summary,lane
R17653 T25940 T25939 prep for,summary
R17654 T25941 T25943 det the,site
R17655 T25942 T25943 compound NFATP2/3,site
R17656 T25943 T25940 pobj site,for
R17657 T25944 T25873 punct ",",A
R17658 T25945 T25957 csubjpass depicting,displayed
R17659 T25946 T25947 det a,decrease
R17660 T25947 T25945 dobj decrease,depicting
R17661 T25948 T25947 prep in,decrease
R17662 T25949 T25950 advmod binding,following
R17663 T25950 T25951 amod following,inhibition
R17664 T25951 T25948 pobj inhibition,in
R17665 T25952 T25953 advmod when,compared
R17666 T25953 T25945 advcl compared,depicting
R17667 T25954 T25953 prep to,compared
R17668 T25955 T25954 pobj GP,to
R17669 T25956 T25957 auxpass is,displayed
R17670 T25957 T25957 ROOT displayed,displayed
R17671 T25958 T25957 punct (,displayed
R17672 T25959 T25961 dep *,p
R17673 T25960 T25961 punct =,p
R17674 T25961 T25957 parataxis p,displayed
R17675 T25962 T25963 nmod <,0.05
R17676 T25963 T25961 npadvmod 0.05,p
R17677 T25964 T25961 punct ),p
R17678 T25965 T25957 punct .,displayed
R17679 T25966 T25968 nsubjpass Data,shown
R17680 T25967 T25968 auxpass are,shown
R17681 T25968 T25968 ROOT shown,shown
R17682 T25969 T25968 prep as,shown
R17683 T25970 T25972 amod mean,SEM
R17684 T25971 T25972 compound ±,SEM
R17685 T25972 T25969 pobj SEM,as
R17686 T25973 T25976 punct (,4
R17687 T25974 T25976 advmod n,4
R17688 T25975 T25976 punct =,4
R17689 T25976 T25972 nummod 4,SEM
R17690 T25977 T25976 punct ),4
R17691 T25978 T25968 punct .,shown
R17692 T25979 T25988 nsubj B,resulted
R17693 T25980 T25979 punct ",",B
R17694 T25981 T25979 conj Inhibition,B
R17695 T25982 T25981 prep of,Inhibition
R17696 T25983 T25982 pobj NFκB,of
R17697 T25984 T25983 punct ",",NFκB
R17698 T25985 T25983 conj NFAT,NFκB
R17699 T25986 T25985 cc and,NFAT
R17700 T25987 T25985 conj NFIL-6,NFAT
R17701 T25988 T25988 ROOT resulted,resulted
R17702 T25989 T25988 prep in,resulted
R17703 T25990 T25992 amod decreased,mRNA
R17704 T25991 T25992 compound IL-1RA,mRNA
R17705 T25992 T25989 pobj mRNA,in
R17706 T25993 T25992 prep following,mRNA
R17707 T25994 T25993 pobj CHX,following
R17708 T25995 T25994 punct ",",CHX
R17709 T25996 T25994 conj CAPE,CHX
R17710 T25997 T25996 cc or,CAPE
R17711 T25998 T25996 conj CyA,CAPE
R17712 T25999 T25988 prep compared,resulted
R17713 T26000 T25999 prep to,compared
R17714 T26001 T26000 pobj GP,to
R17715 T26002 T25988 punct .,resulted
R17716 T26003 T26005 nsubjpass GAPDH,used
R17717 T26004 T26005 auxpass is,used
R17718 T26005 T26005 ROOT used,used
R17719 T26006 T26005 prep as,used
R17720 T26007 T26008 compound housekeeping,control
R17721 T26008 T26006 pobj control,as
R17722 T26009 T26011 punct (,gel
R17723 T26010 T26011 amod representative,gel
R17724 T26011 T26008 appos gel,control
R17725 T26012 T26008 punct ",",control
R17726 T26013 T26008 appos n,control
R17727 T26014 T26015 punct =,4
R17728 T26015 T26013 nummod 4,n
R17729 T26016 T26015 punct ),4
R17730 T26017 T26005 punct .,used
R17731 T26018 T26028 nsubj C,reduced
R17732 T26019 T26018 punct ",",C
R17733 T26020 T26018 appos Inhibition,C
R17734 T26021 T26020 prep of,Inhibition
R17735 T26022 T26021 pobj NFκB,of
R17736 T26023 T26022 punct ",",NFκB
R17737 T26024 T26022 conj NFAT,NFκB
R17738 T26025 T26024 cc and,NFAT
R17739 T26026 T26024 conj NFIL-6,NFAT
R17740 T26027 T26028 advmod significantly,reduced
R17741 T26028 T26028 ROOT reduced,reduced
R17742 T26029 T26030 det the,production
R17743 T26030 T26028 dobj production,reduced
R17744 T26031 T26030 prep of,production
R17745 T26032 T26031 pobj IL-1RA,of
R17746 T26033 T26028 prep by,reduced
R17747 T26034 T26035 compound human,PBMC
R17748 T26035 T26033 pobj PBMC,by
R17749 T26036 T26028 prep following,reduced
R17750 T26037 T26036 pobj treatment,following
R17751 T26038 T26037 prep with,treatment
R17752 T26039 T26038 pobj CHX,with
R17753 T26040 T26039 punct ",",CHX
R17754 T26041 T26039 conj CAPE,CHX
R17755 T26042 T26041 cc or,CAPE
R17756 T26043 T26041 conj CyA,CAPE
R17757 T26044 T26045 advmod when,compared
R17758 T26045 T26028 advcl compared,reduced
R17759 T26046 T26045 prep to,compared
R17760 T26047 T26057 dep GP,p
R17761 T26048 T26047 punct (,GP
R17762 T26049 T26047 prep *,GP
R17763 T26050 T26057 punct =,p
R17764 T26051 T26057 ccomp p,p
R17765 T26052 T26053 nmod <,0.05
R17766 T26053 T26051 npadvmod 0.05,p
R17767 T26054 T26057 punct ;,p
R17768 T26055 T26057 punct **,p
R17769 T26056 T26057 punct =,p
R17770 T26057 T26046 pobj p,to
R17771 T26058 T26059 nmod <,0.01
R17772 T26059 T26057 npadvmod 0.01,p
R17773 T26060 T26057 punct ),p
R17774 T26061 T26028 punct .,reduced
R17775 T26062 T26064 nsubjpass Data,shown
R17776 T26063 T26064 auxpass are,shown
R17777 T26064 T26064 ROOT shown,shown
R17778 T26065 T26064 prep as,shown
R17779 T26066 T26068 amod mean,SEM
R17780 T26067 T26068 compound ±,SEM
R17781 T26068 T26065 pobj SEM,as
R17782 T26069 T26068 punct (,SEM
R17783 T26070 T26072 nmod n,3
R17784 T26071 T26072 punct =,3
R17785 T26072 T26068 prep 3,SEM
R17786 T26073 T26072 punct ),3
R17787 T26074 T26064 punct .,shown
R17829 T26171 T26172 compound Sense,strand
R17830 T26172 T26172 ROOT strand,strand
R17831 T26173 T26172 prep of,strand
R17832 T26174 T26173 pobj oligonucleotides,of
R17833 T26175 T26174 acl used,oligonucleotides
R17834 T26176 T26175 prep in,used
R17835 T26177 T26176 pobj EMSAs,in
R17836 T26178 T26172 punct .,strand
R17878 T26239 T26239 ROOT Cartoon,Cartoon
R17879 T26240 T26239 prep of,Cartoon
R17880 T26241 T26243 det the,strand
R17881 T26242 T26243 compound sense,strand
R17882 T26243 T26240 pobj strand,of
R17883 T26244 T26243 prep of,strand
R17884 T26245 T26247 det the,promoter
R17885 T26246 T26247 compound IL-1RA,promoter
R17886 T26247 T26244 pobj promoter,of
R17887 T26248 T26239 punct .,Cartoon
R17888 T26249 T26250 amod Relative,locations
R17889 T26250 T26281 nsubjpass locations,depicted
R17890 T26251 T26250 prep of,locations
R17891 T26252 T26281 advmod previously,depicted
R17892 T26253 T26256 punct (,[
R17893 T26254 T26256 nmod LRE-1,[
R17894 T26255 T26256 punct ),[
R17895 T26256 T26281 nsubjpass [,depicted
R17896 T26257 T26256 nummod 30-33,[
R17897 T26258 T26256 conj ],[
R17898 T26259 T26258 cc and,]
R17899 T26260 T26261 advmod newly,described
R17900 T26261 T26281 advcl described,depicted
R17901 T26262 T26261 punct (,described
R17902 T26263 T26261 parataxis boxed,described
R17903 T26264 T26263 punct ),boxed
R17904 T26265 T26261 punct ",",described
R17905 T26266 T26281 advmod positively,depicted
R17906 T26267 T26281 punct (,depicted
R17907 T26268 T26279 amod black,sites
R17908 T26269 T26268 punct ),black
R17909 T26270 T26268 cc and,black
R17910 T26271 T26279 nmod negatively,sites
R17911 T26272 T26277 punct (,factor
R17912 T26273 T26277 amod gray,factor
R17913 T26274 T26277 punct ),factor
R17914 T26275 T26277 amod regulatory,factor
R17915 T26276 T26277 compound transcription,factor
R17916 T26277 T26279 nmod factor,sites
R17917 T26278 T26279 amod binding,sites
R17918 T26279 T26281 nsubjpass sites,depicted
R17919 T26280 T26281 auxpass are,depicted
R17920 T26281 T26281 ROOT depicted,depicted
R17921 T26282 T26281 punct .,depicted
R1130 T2206 T2207 compound recognition,receptor
R1131 T2207 T2202 attr receptor,be
R1132 T2208 T2207 punct (,receptor
R1133 T2209 T2207 appos PRR,receptor
R1134 T2210 T2207 punct ),receptor
R1136 T2211 T2207 prep for,receptor
R1137 T2212 T2213 amod intact,yeast
R1138 T2213 T2211 pobj yeast,for
R1139 T2214 T2213 cc and,yeast
R1141 T2215 T2216 amod β-1,→
R1142 T2216 T2218 compound →,particles
R1143 T2217 T2218 compound 3-D-glucan-containing,particles
R1145 T2218 T2213 conj particles,yeast
R1146 T2219 T2221 punct (,zymosan
R1147 T2220 T2221 advmod i.e.,zymosan
R1149 T2221 T2218 appos zymosan,particles
R1150 T2222 T2218 punct ),particles
R1151 T2223 T2207 prep on,receptor
R1153 T2224 T2223 pobj monocytes/macrophages,on
R1154 T2225 T2227 advmod as,as
R1155 T2226 T2227 advmod well,as
R1157 T2227 T2224 cc as,monocytes/macrophages
R1158 T2228 T2224 conj neutrophils,monocytes/macrophages
R1159 T2229 T2223 cc and,on
R1160 T2230 T2223 conj on,on
R1162 T2231 T2232 amod primary,cells
R1163 T2232 T2230 pobj cells,on
R1164 T2233 T2235 nmod [,]
R1165 T2234 T2235 nummod 7-11,]
R1166 T2235 T2232 appos ],cells
R1167 T2236 T2200 punct .,demonstrated
R1168 T2128 T2131 amod non-pathogenic,fungi
R1169 T2237 T2247 prep In,resulted
R1170 T2238 T2240 det the,system
R1171 T2239 T2240 compound murine,system
R1172 T2240 T2237 pobj system,In
R1173 T2129 T2128 cc and,non-pathogenic
R1174 T2241 T2247 punct ",",resulted
R1175 T2242 T2247 nsubj binding,resulted
R1176 T2130 T2128 conj pathogenic,non-pathogenic
R1177 T2243 T2242 prep of,binding
R1178 T2131 T2125 pobj fungi,from
R1179 T2244 T2243 pobj zymosan,of
R1180 T2245 T2247 prep to,resulted
R1181 T2246 T2245 pobj Dectin-1,to
R1182 T2132 T2133 amod such,as
R1183 T2133 T2131 prep as,fungi
R1184 T2247 T2247 ROOT resulted,resulted
R1185 T2134 T2135 compound S.,cerevisae
R1186 T2248 T2247 prep in,resulted
R1187 T2249 T2248 pobj production,in
R1188 T2250 T2249 prep of,production
R1189 T2251 T2250 pobj TNFα,of
R1190 T2135 T2133 pobj cerevisae,as
R1191 T2252 T2247 prep through,resulted
R1192 T2253 T2254 amod Toll-like,receptor
R1193 T2136 T2135 cc and,cerevisae
R1194 T2254 T2252 pobj receptor,through
R1195 T2255 T2254 nummod 2,receptor
R1196 T2256 T2254 cc and,receptor
R1197 T2137 T2135 conj C.,cerevisae
R1198 T2257 T2259 det the,protein
R1199 T2258 T2259 compound adaptor,protein
R1200 T2259 T2254 conj protein,receptor
R1201 T2138 T2124 conj albicans,secreted
R1202 T2260 T2261 compound MyD88,[
R1203 T2261 T2259 appos [,protein
R1204 T2262 T2263 nummod 12,]
R1205 T2139 T2141 nmod [,]
R1206 T2263 T2261 appos ],[
R1207 T2264 T2247 punct .,resulted
R1208 T2265 T2269 det Another,3-D-glucan
R1209 T2140 T2139 nummod 1,[
R1210 T2266 T2269 amod water-soluble,3-D-glucan
R1211 T2267 T2269 amod β-1,3-D-glucan
R1212 T2141 T2138 appos ],albicans
R1213 T2268 T2269 compound →,3-D-glucan
R1214 T2269 T2275 nsubjpass 3-D-glucan,described
R1215 T2270 T2271 punct (,PGG-glucan
R1216 T2271 T2269 appos PGG-glucan,3-D-glucan
R1217 T2272 T2271 punct ),PGG-glucan
R1218 T2273 T2275 aux has,described
R1219 T2274 T2275 auxpass been,described
R1220 T2142 T2112 punct .,occur
R1221 T2275 T2275 ROOT described,described
R1222 T2276 T2277 aux to,activate
R1223 T2277 T2275 xcomp activate,described
R1224 T2143 T2148 det These,polymers
R1225 T2278 T2277 dobj NFκB,activate
R1226 T2279 T2278 cc and,NFκB
R1227 T2280 T2278 conj NFIL-6,NFκB
R1228 T2144 T2148 amod β-1,polymers
R1229 T2281 T2277 prep in,activate
R1230 T2282 T2284 amod murine,lines
R1231 T2145 T2148 amod →,polymers
R1232 T2283 T2284 compound cell,lines
R1233 T2284 T2281 pobj lines,in
R1234 T2285 T2287 compound [,]
R1235 T2146 T2148 amod 3-D-linked,polymers
R1236 T2286 T2287 compound "13,14",]
R1237 T2287 T2287 ROOT ],]
R1238 T2288 T2275 punct .,described
R1239 T2147 T2148 compound glucose,polymers
R1240 T2289 T2294 advmod Similarly,shown
R1241 T2290 T2294 punct ",",shown
R1242 T2291 T2294 nsubjpass it,shown
R1243 T2148 T2150 nsubjpass polymers,characterized
R1244 T2292 T2294 aux has,shown
R1245 T2293 T2294 auxpass been,shown
R1246 T2294 T2294 ROOT shown,shown
R1247 T2149 T2150 auxpass are,characterized
R1248 T2295 T2299 mark that,activate
R1249 T2296 T2298 amod β-1,3-D-glucans
R1250 T2297 T2298 compound →,3-D-glucans
R1251 T2150 T2150 ROOT characterized,characterized
R1252 T2298 T2299 nsubj 3-D-glucans,activate
R1253 T2299 T2294 ccomp activate,shown
R1254 T2300 T2299 dobj NFκB,activate
R1255 T2151 T2150 prep as,characterized
R1256 T2301 T2299 prep in,activate
R1257 T2302 T2306 det a,line
R1258 T2152 T2156 det a,pattern
R1259 T2153 T2156 amod fungal,pattern
R1260 T2154 T2156 amod pathogen-associated,pattern
R1261 T2303 T2305 amod human,cell
R1262 T2304 T2305 amod monocyte-like,cell
R1263 T2155 T2156 amod molecular,pattern
R1264 T2305 T2306 compound cell,line
R1265 T2306 T2301 pobj line,in
R1266 T2307 T2309 nmod [,]
R1267 T2308 T2309 nummod 15,]
R1268 T2309 T2306 appos ],line
R1269 T2310 T2301 cc and,in
R1270 T2156 T2151 pobj pattern,as
R1271 T2311 T2301 conj in,in
R1272 T2312 T2313 amod human,polymorphonuclear
R1273 T2313 T2314 compound polymorphonuclear,neutrophils
R1274 T2157 T2156 punct (,pattern
R1275 T2314 T2311 pobj neutrophils,in
R1276 T2315 T2316 punct (,PMN
R1277 T2316 T2314 appos PMN,neutrophils
R1278 T2158 T2156 appos PAMP,pattern
R1279 T2317 T2314 punct ),neutrophils
R1280 T2318 T2311 punct ",",in
R1281 T2159 T2156 punct ),pattern
R1282 T2319 T2311 conj in,in
R1283 T2320 T2322 det the,case
R1284 T2321 T2322 amod latter,case
R1285 T2160 T2162 nmod [,]
R1286 T2322 T2319 pobj case,in
R1287 T2323 T2322 prep without,case
R1288 T2324 T2323 pobj secretion,without
R1289 T2161 T2162 nummod 2,]
R1290 T2325 T2324 prep of,secretion
R1291 T2162 T2156 appos ],pattern
R1292 T2326 T2327 amod pro-inflammatory,cytokines
R1293 T2163 T2150 punct .,characterized
R1294 T2327 T2325 pobj cytokines,of
R1295 T2328 T2337 punct (,]
R1296 T2329 T2337 amod IL-1,]
R1297 T2330 T2335 punct ",",[
R1298 T2164 T2167 det The,recognition
R1299 T2331 T2335 nmod IL-6,[
R1300 T2332 T2331 punct ",",IL-6
R1301 T2333 T2331 conj TNFα,IL-6
R1302 T2165 T2167 amod primary,recognition
R1303 T2334 T2335 punct ),[
R1304 T2335 T2337 nmod [,]
R1305 T2166 T2167 amod cellular,recognition
R1306 T2336 T2337 nummod 16,]
R1307 T2337 T2299 npadvmod ],activate
R1308 T2338 T2294 punct .,shown
R1309 T2339 T2340 nummod One,study
R1310 T2167 T2173 nsubjpass recognition,mediated
R1311 T2340 T2341 nsubj study,proposed
R1312 T2341 T2341 ROOT proposed,proposed
R1313 T2342 T2357 mark that,be
R1314 T2168 T2167 prep of,recognition
R1315 T2343 T2344 det the,production
R1316 T2344 T2357 nsubj production,be
R1317 T2345 T2344 prep of,production
R1318 T2346 T2348 det the,IL-1RA
R1319 T2347 T2348 amod anti-inflammatory,IL-1RA
R1320 T2169 T2171 amod β-1,3-D-glucans
R1321 T2348 T2345 pobj IL-1RA,of
R1322 T2349 T2344 punct ",",production
R1323 T2350 T2344 cc but,production
R1324 T2351 T2352 neg not,IL-1
R1325 T2352 T2344 conj IL-1,production
R1326 T2170 T2171 compound →,3-D-glucans
R1327 T2353 T2344 prep by,production
R1328 T2354 T2355 amod human,monocytes
R1329 T2355 T2353 pobj monocytes,by
R1330 T2171 T2168 pobj 3-D-glucans,of
R1331 T2356 T2357 aux may,be
R1332 T2357 T2341 ccomp be,proposed
R1333 T2358 T2361 det a,mechanism
R1334 T2172 T2173 auxpass is,mediated
R1335 T2359 T2360 advmod potentially,protective
R1336 T2360 T2361 amod protective,mechanism
R1337 T2173 T2173 ROOT mediated,mediated
R1338 T2361 T2357 attr mechanism,be
R1339 T2362 T2361 acl induced,mechanism
R1340 T2363 T2362 agent by,induced
R1341 T2174 T2173 agent by,mediated
R1342 T2364 T2365 amod β-1,→
R1343 T2365 T2367 nmod →,[
R1344 T2366 T2367 compound 3-D-glucan,[
R1345 T2175 T2179 amod several,receptors
R1346 T2367 T2363 pobj [,by
R1347 T2368 T2369 nummod 17,]
R1348 T2369 T2367 appos ],[
R1349 T2370 T2341 punct .,proposed
R1350 T2176 T2179 amod β-1,receptors
R1351 T2371 T2373 nummod Three,investigations
R1352 T2372 T2373 amod other,investigations
R1353 T2373 T2375 nsubj investigations,reported
R1354 T2177 T2179 nmod →,receptors
R1355 T2374 T2375 aux have,reported
R1356 T2375 T2375 ROOT reported,reported
R1357 T2376 T2384 mark that,produce
R1358 T2178 T2179 amod 3-D-glucan,receptors
R1359 T2377 T2378 amod human,leukocytes
R1360 T2378 T2384 nsubj leukocytes,produce
R1361 T2379 T2378 cc and,leukocytes
R1362 T2179 T2174 pobj receptors,by
R1363 T2180 T2179 prep on,receptors
R1364 T2380 T2383 amod human,cells
R1365 T2181 T2180 pobj phagocytes,on
R1366 T2381 T2383 amod vascular,cells
R1367 T2382 T2383 amod endothelial,cells
R1368 T2383 T2378 conj cells,leukocytes
R1369 T2384 T2375 ccomp produce,reported
R1370 T2385 T2384 dobj IL-8,produce
R1371 T2182 T2184 compound [,]
R1372 T2386 T2384 prep in,produce
R1373 T2387 T2386 pobj response,in
R1374 T2388 T2389 aux to,zymosan
R1375 T2389 T2384 advcl zymosan,produce
R1376 T2183 T2184 compound "3,4",]
R1377 T2390 T2392 det [,]
R1378 T2391 T2392 nummod 18,]
R1379 T2392 T2389 dobj ],zymosan
R1380 T2184 T2179 appos ],receptors
R1381 T2393 T2392 cc or,]
R1382 T2394 T2397 det a,→
R1383 T2395 T2397 amod water-soluble,→
R1384 T2185 T2184 cc and,]
R1385 T2396 T2397 amod β-1,→
R1386 T2186 T2187 amod other,cells
R1387 T2397 T2392 conj →,]
R1388 T2398 T2399 compound 3-D-glucan,[
R1389 T2399 T2397 appos [,→
R1390 T2187 T2184 conj cells,]
R1391 T2188 T2190 compound [,]
R1392 T2189 T2190 compound "5,6",]
R1393 T2190 T2184 conj ],]
R1394 T2400 T2401 compound "6,19",]
R1395 T2401 T2397 appos ],→
R1396 T2402 T2375 punct .,reported
R1397 T2191 T2173 punct .,mediated
R1398 T2403 T2409 prep In,seem
R1399 T2404 T2403 pobj addition,In
R1400 T2192 T2200 nsubj Human,demonstrated
R1401 T2193 T2195 advmod as,as
R1402 T2405 T2409 punct ",",seem
R1403 T2194 T2195 advmod well,as
R1404 T2406 T2408 amod β-1,3-D-glucans
R1405 T2407 T2408 compound →,3-D-glucans
R1406 T2195 T2192 cc as,Human
R1407 T2408 T2409 nsubj 3-D-glucans,seem
R1408 T2409 T2409 ROOT seem,seem
R1409 T2410 T2411 aux to,be
R1410 T2196 T2197 amod murine,Dectin-1
R1411 T2411 T2409 xcomp be,seem
R1412 T2412 T2411 acomp able,be
R1413 T2197 T2200 nsubjpass Dectin-1,demonstrated
R1414 T2413 T2414 aux to,modify
R1415 T2414 T2412 xcomp modify,able
R1416 T2415 T2416 det the,response
R1417 T2416 T2414 dobj response,modify
R1418 T2417 T2418 aux to,pro-inflammatory
R1419 T2418 T2416 relcl pro-inflammatory,response
R1420 T2198 T2200 aux has,demonstrated
R1421 T2419 T2418 dobj stimuli,pro-inflammatory
R1422 T2420 T2419 cc or,stimuli
R1423 T2421 T2422 advmod even,sepsis
R1424 T2422 T2419 conj sepsis,stimuli
R1425 T2199 T2200 auxpass been,demonstrated
R1426 T2423 T2409 punct .,seem
R1427 T2424 T2438 prep In,resulted
R1428 T2425 T2429 det a,model
R1429 T2200 T2200 ROOT demonstrated,demonstrated
R1430 T2426 T2429 amod murine,model
R1431 T2427 T2429 amod polymicrobial,model
R1432 T2428 T2429 compound sepsis,model
R1433 T2201 T2202 aux to,be
R1434 T2429 T2424 pobj model,In
R1435 T2430 T2438 punct ",",resulted
R1436 T2431 T2432 amod β-1,→
R1437 T2202 T2200 xcomp be,demonstrated
R1438 T2432 T2434 compound →,[
R1439 T2433 T2434 compound 3-D-glucan,[
R1440 T2203 T2207 det the,receptor
R1441 T2434 T2438 nsubj [,resulted
R1442 T2435 T2437 nummod 20,treatment
R1443 T2204 T2207 amod major,receptor
R1444 T2436 T2437 compound ],treatment
R1445 T2437 T2438 nsubj treatment,resulted
R1446 T2438 T2438 ROOT resulted,resulted
R1447 T2205 T2206 compound pattern,recognition
R1448 T2439 T2438 prep in,resulted
R1449 T2440 T2442 amod decreased,morbidity
R1450 T2441 T2442 amod septic,morbidity
R1451 T2497 T2498 amod beneficial,effects
R1452 T2442 T2439 pobj morbidity,in
R1453 T2443 T2442 cc and,morbidity
R1454 T2444 T2442 conj mortality,morbidity
R1455 T2498 T2495 dobj effects,underlying
R1456 T2445 T2438 conj mediated,resulted
R1457 T2446 T2445 prep via,mediated
R1458 T2447 T2446 pobj inhibition,via
R1459 T2499 T2498 prep of,effects
R1460 T2448 T2447 prep of,inhibition
R1461 T2449 T2448 pobj NFκB,of
R1462 T2450 T2447 cc and,inhibition
R1463 T2451 T2447 conj stimulation,inhibition
R1464 T2500 T2502 amod β-1,3-D-glucan
R1465 T2452 T2447 prep of,inhibition
R1466 T2453 T2454 det the,phosphoinositide-3-kinase
R1467 T2454 T2452 pobj phosphoinositide-3-kinase,of
R1468 T2455 T2458 punct (,pathway
R1469 T2456 T2458 nmod PI3K,pathway
R1470 T2501 T2502 compound →,3-D-glucan
R1471 T2457 T2458 punct ),pathway
R1472 T2458 T2454 appos pathway,phosphoinositide-3-kinase
R1473 T2459 T2461 compound [,]
R1474 T2502 T2499 pobj 3-D-glucan,of
R1475 T2460 T2461 compound "21,22",]
R1476 T2461 T2458 appos ],pathway
R1477 T2462 T2438 punct .,resulted
R1478 T2503 T2506 auxpass are,resolved
R1479 T2463 T2480 nsubj These,support
R1480 T2464 T2463 cc and,These
R1481 T2465 T2467 amod other,studies
R1482 T2466 T2467 compound animal,studies
R1483 T2504 T2505 advmod only,partially
R1484 T2467 T2463 conj studies,These
R1485 T2468 T2470 compound [,]
R1486 T2469 T2470 compound "23,24",]
R1487 T2505 T2506 advmod partially,resolved
R1488 T2470 T2467 appos ],studies
R1489 T2471 T2473 advmod as,as
R1490 T2472 T2473 advmod well,as
R1491 T2506 T2506 ROOT resolved,resolved
R1492 T2473 T2467 cc as,studies
R1493 T2507 T2506 punct ",",resolved
R1494 T2474 T2476 det a,trial
R1495 T2475 T2476 amod clinical,trial
R1496 T2476 T2467 conj trial,studies
R1497 T2477 T2480 nsubj [,support
R1498 T2508 T2509 advmod especially,in
R1499 T2478 T2480 nummod 25,support
R1500 T2479 T2480 amod ],support
R1501 T2480 T2480 ROOT support,support
R1502 T2509 T2506 prep in,resolved
R1503 T2481 T2483 det a,role
R1504 T2482 T2483 amod protective,role
R1505 T2483 T2480 dobj role,support
R1506 T2510 T2509 pobj humans,in
R1507 T2511 T2506 punct .,resolved
R1508 T2484 T2483 prep of,role
R1509 T2485 T2487 amod β-1,3-D-glucan
R1510 T2512 T2519 advmod Thus,was
R1511 T2486 T2487 compound →,3-D-glucan
R1512 T2487 T2484 pobj 3-D-glucan,of
R1513 T2488 T2487 prep in,3-D-glucan
R1514 T2513 T2519 punct ",",was
R1515 T2489 T2491 amod certain,conditions
R1516 T2490 T2491 amod pro-inflammatory,conditions
R1517 T2491 T2488 pobj conditions,in
R1518 T2492 T2480 punct .,support
R1519 T2493 T2494 det The,mechanisms
R1520 T2494 T2503 nsubj mechanisms,are
R1521 T2514 T2515 det the,aim
R1522 T2495 T2494 acl underlying,mechanisms
R1523 T2496 T2498 det these,effects
R1524 T2515 T2519 nsubj aim,was
R1525 T2516 T2515 prep of,aim
R1526 T2517 T2518 det this,study
R1527 T2518 T2516 pobj study,of
R1528 T2519 T2519 ROOT was,was
R1529 T2594 T2595 nummod 48,h.
R1530 T2595 T2596 compound h.,Because
R1531 T2520 T2521 aux to,elucidate
R1532 T2596 T2622 prep Because,measured
R1533 T2597 T2596 pcomp of,Because
R1534 T2598 T2600 det the,effect
R1535 T2521 T2519 xcomp elucidate,was
R1536 T2599 T2600 amod potential,effect
R1537 T2600 T2622 nsubjpass effect,measured
R1538 T2601 T2600 prep of,effect
R1539 T2522 T2525 amod molecular,mechanisms
R1540 T2602 T2604 amod β-1,3-D-glucan
R1541 T2603 T2604 compound →,3-D-glucan
R1542 T2604 T2601 pobj 3-D-glucan,of
R1543 T2523 T2522 cc and,molecular
R1544 T2605 T2604 prep on,3-D-glucan
R1545 T2606 T2607 compound cytokine,production
R1546 T2607 T2610 compound production,]
R1547 T2524 T2522 conj cellular,molecular
R1548 T2608 T2610 compound [,]
R1549 T2525 T2521 dobj mechanisms,elucidate
R1550 T2609 T2610 compound "12,16-19",]
R1551 T2610 T2605 pobj ],on
R1552 T2611 T2610 punct ",",]
R1553 T2526 T2525 prep of,mechanisms
R1554 T2612 T2610 conj TNFα,]
R1555 T2613 T2612 punct ",",TNFα
R1556 T2614 T2612 conj IL-1β,TNFα
R1557 T2527 T2529 amod β-1,3-D-glucans
R1558 T2615 T2614 punct ",",IL-1β
R1559 T2616 T2614 conj IL-6,IL-1β
R1560 T2617 T2616 punct ",",IL-6
R1561 T2528 T2529 compound →,3-D-glucans
R1562 T2618 T2616 conj IL-8,IL-6
R1563 T2619 T2618 cc and,IL-8
R1564 T2529 T2526 pobj 3-D-glucans,of
R1565 T2620 T2618 conj IL-1RA,IL-8
R1566 T2621 T2622 auxpass were,measured
R1567 T2622 T2560 advcl measured,exposed
R1568 T2623 T2625 advmod as,as
R1569 T2624 T2625 advmod well,as
R1570 T2625 T2622 cc as,measured
R1571 T2626 T2625 pobj IFNγ,as
R1572 T2530 T2525 prep on,mechanisms
R1573 T2627 T2626 punct ",",IFNγ
R1574 T2628 T2626 conj IL-2,IFNγ
R1575 T2629 T2628 punct ",",IL-2
R1576 T2531 T2532 amod human,leukocytes
R1577 T2630 T2628 conj IL-4,IL-2
R1578 T2631 T2630 punct ",",IL-4
R1579 T2632 T2630 conj IL-10,IL-4
R1580 T2532 T2530 pobj leukocytes,on
R1581 T2633 T2632 punct ",",IL-10
R1582 T2634 T2632 conj IL-12,IL-10
R1583 T2635 T2634 cc and,IL-12
R1584 T2533 T2521 prep in,elucidate
R1585 T2636 T2634 conj TGFβ1,IL-12
R1586 T2637 T2622 punct .,measured
R1587 T2638 T2699 advmod Correspondingly,examined
R1588 T2639 T2699 punct ",",examined
R1589 T2534 T2535 amod pro-inflammatory,conditions
R1590 T2640 T2642 nummod four,sites
R1591 T2535 T2533 pobj conditions,in
R1592 T2536 T2521 prep with,elucidate
R1593 T2641 T2642 compound NFκB,sites
R1594 T2642 T2699 nsubjpass sites,examined
R1595 T2537 T2538 amod special,emphasis
R1596 T2643 T2642 prep from,sites
R1597 T2644 T2646 det the,promoter
R1598 T2645 T2646 compound TNFα,promoter
R1599 T2538 T2536 pobj emphasis,with
R1600 T2646 T2643 pobj promoter,from
R1601 T2647 T2646 punct (,promoter
R1602 T2648 T2649 nmod κ,consensus
R1603 T2539 T2538 prep on,emphasis
R1604 T2649 T2646 appos consensus,promoter
R1605 T2650 T2649 punct ",",consensus
R1606 T2540 T2542 det the,profile
R1607 T2651 T2649 appos κ1,consensus
R1608 T2652 T2651 punct ",",κ1
R1609 T2653 T2651 conj κ2,κ1
R1610 T2541 T2542 compound cytokine,profile
R1611 T2654 T2653 punct ",",κ2
R1612 T2655 T2653 conj κ3,κ2
R1613 T2656 T2646 punct ),promoter
R1614 T2542 T2539 pobj profile,on
R1615 T2657 T2659 nmod [,]
R1616 T2658 T2659 nummod 27,]
R1617 T2659 T2642 appos ],sites
R1618 T2660 T2659 punct ",",]
R1619 T2661 T2664 det a,site
R1620 T2662 T2664 compound κ,site
R1621 T2543 T2542 cc and,profile
R1622 T2663 T2664 compound consensus,site
R1623 T2664 T2659 appos site,]
R1624 T2665 T2664 prep from,site
R1625 T2544 T2546 poss its,regulation
R1626 T2666 T2668 det the,promoter
R1627 T2667 T2668 compound IL-8,promoter
R1628 T2668 T2671 compound promoter,]
R1629 T2669 T2671 compound [,]
R1630 T2545 T2546 amod transcriptional,regulation
R1631 T2670 T2671 compound 28,]
R1632 T2671 T2665 pobj ],from
R1633 T2672 T2671 punct ",",]
R1634 T2546 T2542 conj regulation,profile
R1635 T2673 T2675 det an,site
R1636 T2674 T2675 compound NFAT,site
R1637 T2675 T2671 appos site,]
R1638 T2547 T2519 punct .,was
R1639 T2676 T2675 prep from,site
R1640 T2677 T2679 det the,promoter
R1641 T2678 T2679 compound IFNγ,promoter
R1642 T2548 T2560 prep For,exposed
R1643 T2679 T2676 pobj promoter,from
R1644 T2680 T2679 punct (,promoter
R1645 T2549 T2550 det this,purpose
R1646 T2681 T2679 appos ATP2,promoter
R1647 T2682 T2679 punct ),promoter
R1648 T2683 T2699 nsubjpass [,examined
R1649 T2550 T2548 pobj purpose,For
R1650 T2684 T2685 nummod 29,]
R1651 T2685 T2683 meta ],[
R1652 T2686 T2683 cc and,[
R1653 T2551 T2560 punct ",",exposed
R1654 T2687 T2690 det a,site
R1655 T2688 T2690 compound consensus,site
R1656 T2689 T2690 compound NFIL-6,site
R1657 T2690 T2683 conj site,[
R1658 T2552 T2555 amod peripheral,cells
R1659 T2553 T2554 compound blood,mononuclear
R1660 T2554 T2555 compound mononuclear,cells
R1661 T2691 T2690 prep from,site
R1662 T2692 T2694 det the,promoter
R1663 T2555 T2560 nsubjpass cells,exposed
R1664 T2693 T2694 compound IL-6,promoter
R1665 T2694 T2691 pobj promoter,from
R1666 T2556 T2555 punct (,cells
R1667 T2695 T2690 appos [,site
R1668 T2696 T2697 nummod 13,]
R1669 T2697 T2690 conj ],site
R1670 T2698 T2699 auxpass were,examined
R1671 T2699 T2699 ROOT examined,examined
R1672 T2700 T2699 punct .,examined
R1673 T2557 T2555 appos PBMC,cells
R1674 T2701 T2710 prep Because,focused
R1675 T2702 T2701 pcomp of,Because
R1676 T2703 T2705 det the,role
R1677 T2704 T2705 amod anti-inflammatory,role
R1678 T2558 T2555 punct ),cells
R1679 T2705 T2701 pobj role,Because
R1680 T2706 T2705 prep of,role
R1681 T2559 T2560 auxpass were,exposed
R1682 T2707 T2706 pobj IL-1RA,of
R1683 T2708 T2710 punct ",",focused
R1684 T2709 T2710 nsubj we,focused
R1685 T2560 T2560 ROOT exposed,exposed
R1686 T2710 T2710 ROOT focused,focused
R1687 T2711 T2710 prep on,focused
R1688 T2712 T2711 pobj binding,on
R1689 T2561 T2560 prep to,exposed
R1690 T2713 T2712 prep of,binding
R1691 T2714 T2715 compound transcription,factors
R1692 T2715 T2713 pobj factors,of
R1693 T2562 T2566 det a,3-D-glucan
R1694 T2716 T2712 prep to,binding
R1695 T2717 T2719 det the,promoter
R1696 T2563 T2566 amod well-defined,3-D-glucan
R1697 T2718 T2719 compound IL-1RA,promoter
R1698 T2564 T2566 amod β-1,3-D-glucan
R1699 T2719 T2716 pobj promoter,to
R1700 T2720 T2710 punct .,focused
R1701 T2721 T2723 det An,element
R1702 T2565 T2566 compound →,3-D-glucan
R1703 T2722 T2723 amod inhibitory,element
R1704 T2723 T2752 nsubjpass element,characterized
R1705 T2724 T2723 cc and,element
R1706 T2725 T2728 nummod three,elements
R1707 T2566 T2561 pobj 3-D-glucan,to
R1708 T2726 T2728 amod positive-acting,elements
R1709 T2727 T2728 amod LPS-response,elements
R1710 T2567 T2566 punct ",",3-D-glucan
R1711 T2728 T2723 conj elements,element
R1712 T2729 T2728 punct (,elements
R1713 T2730 T2728 appos LRE-1,elements
R1714 T2731 T2730 punct ",",LRE-1
R1715 T2568 T2570 advmod i.e.,phosphate
R1716 T2732 T2730 conj LRE-2,LRE-1
R1717 T2733 T2732 cc and,LRE-2
R1718 T2569 T2570 nmod glucan,phosphate
R1719 T2734 T2732 conj LRE-3,LRE-2
R1720 T2735 T2728 punct ),elements
R1721 T2736 T2723 prep in,element
R1722 T2737 T2739 det the,promoter
R1723 T2738 T2739 compound IL-1RA,promoter
R1724 T2739 T2736 pobj promoter,in
R1725 T2740 T2723 punct ",",element
R1726 T2570 T2566 appos phosphate,3-D-glucan
R1727 T2741 T2723 prep including,element
R1728 T2742 T2741 pobj NFκB,including
R1729 T2743 T2742 punct ",",NFκB
R1730 T2571 T2574 punct (,[
R1731 T2744 T2748 nmod PU,sites
R1732 T2745 T2744 nummod .1,PU
R1733 T2572 T2574 nmod GP,[
R1734 T2573 T2574 punct ),[
R1735 T2746 T2744 cc and,PU
R1736 T2574 T2576 compound [,]
R1737 T2747 T2744 conj NFIL-6,PU
R1738 T2748 T2742 appos sites,NFκB
R1739 T2575 T2576 compound "20,26",]
R1740 T2749 T2742 punct ",",NFκB
R1741 T2750 T2752 aux have,characterized
R1742 T2751 T2752 auxpass been,characterized
R1743 T2576 T2566 appos ],3-D-glucan
R1744 T2752 T2752 ROOT characterized,characterized
R1745 T2753 T2756 advmod previously,]
R1746 T2754 T2756 compound [,]
R1747 T2755 T2756 compound 30-33,]
R1748 T2577 T2576 punct ",",]
R1749 T2756 T2752 dobj ],characterized
R1750 T2757 T2752 punct .,characterized
R1751 T2758 T2769 advcl Using,looked
R1752 T2578 T2576 advmod alone,]
R1753 T2759 T2760 amod computational,analysis
R1754 T2579 T2578 cc or,alone
R1755 T2760 T2758 dobj analysis,Using
R1756 T2761 T2760 prep for,analysis
R1757 T2762 T2763 compound homology,search
R1758 T2580 T2578 conj simultaneously,alone
R1759 T2763 T2761 pobj search,for
R1760 T2764 T2766 nmod [,]
R1761 T2765 T2766 nummod 34,]
R1762 T2581 T2578 prep with,alone
R1763 T2766 T2769 npadvmod ],looked
R1764 T2767 T2769 punct ",",looked
R1765 T2768 T2769 nsubj we,looked
R1766 T2582 T2581 pobj LPS,with
R1767 T2769 T2769 ROOT looked,looked
R1768 T2770 T2769 prep for,looked
R1769 T2771 T2773 amod new,motifs
R1770 T2772 T2773 amod binding,motifs
R1771 T2773 T2770 pobj motifs,for
R1772 T2774 T2773 prep in,motifs
R1773 T2583 T2582 prep from,LPS
R1774 T2775 T2777 det the,promoter
R1775 T2776 T2777 compound IL-1RA,promoter
R1776 T2777 T2774 pobj promoter,in
R1777 T2584 T2585 amod gram-negative,bacteria
R1778 T2778 T2769 punct .,looked
R1779 T2585 T2583 pobj bacteria,from
R1780 T2586 T2585 cc or,bacteria
R1781 T2587 T2589 det the,TSST-1
R1782 T2588 T2589 compound superantigen,TSST-1
R1783 T2589 T2585 conj TSST-1,bacteria
R1784 T2590 T2589 prep from,TSST-1
R1785 T2591 T2592 amod gram-positive,bacteria
R1786 T2592 T2590 pobj bacteria,from
R1787 T2593 T2594 quantmod over,48
R2346 T3832 T3833 compound Binding,activities
R2347 T3833 T3875 nsubj activities,induced
R2348 T3834 T3833 prep of,activities
R2349 T3835 T3834 pobj NFκB,of
R2350 T3836 T3835 punct ",",NFκB
R2351 T3837 T3835 conj NFIL-6,NFκB
R2352 T3838 T3837 cc and,NFIL-6
R2353 T3839 T3837 conj NFAT,NFIL-6
R2354 T3840 T3833 prep from,activities
R2355 T3841 T3842 compound human,PBMC
R2356 T3842 T3840 pobj PBMC,from
R2357 T3843 T3833 prep to,activities
R2358 T3844 T3845 det the,TNFα
R2359 T3845 T3843 pobj TNFα,to
R2360 T3846 T3845 punct ",",TNFα
R2361 T3847 T3845 conj IL-6,TNFα
R2362 T3848 T3847 cc and,IL-6
R2363 T3849 T3847 conj IFNγ,IL-6
R2364 T3850 T3833 conj promoters,activities
R2365 T3851 T3833 acl following,activities
R2366 T3852 T3858 det an,h
R2367 T3853 T3858 nmod in,h
R2368 T3854 T3855 amod vitro,stimulation
R2369 T3855 T3853 pobj stimulation,in
R2370 T3856 T3858 punct (,h
R2371 T3857 T3858 nummod 1,h
R2372 T3858 T3851 pobj h,following
R2373 T3859 T3833 punct ),activities
R2374 T3860 T3833 prep with,activities
R2375 T3861 T3860 pobj LPS,with
R2376 T3862 T3861 punct ",",LPS
R2377 T3863 T3861 conj TSST-1,LPS
R2378 T3864 T3863 punct ",",TSST-1
R2379 T3865 T3863 conj GP,TSST-1
R2380 T3866 T3865 punct ",",GP
R2381 T3867 T3869 compound GP,LPS
R2382 T3868 T3869 compound +,LPS
R2383 T3869 T3865 conj LPS,GP
R2384 T3870 T3869 cc and,LPS
R2385 T3871 T3874 compound GP,GP
R2386 T3872 T3874 compound +,GP
R2387 T3873 T3874 compound TSST-1,GP
R2388 T3874 T3869 conj GP,LPS
R2389 T3875 T3925 ccomp induced,1A
R2390 T3876 T3877 compound band,shifts
R2391 T3877 T3875 dobj shifts,induced
R2392 T3878 T3875 punct ",",induced
R2393 T3879 T3875 advcl indicating,induced
R2394 T3880 T3879 dobj binding,indicating
R2395 T3881 T3880 prep of,binding
R2396 T3882 T3881 pobj NFκB,of
R2397 T3883 T3885 advmod as,as
R2398 T3884 T3885 advmod well,as
R2399 T3885 T3879 cc as,indicating
R2400 T3886 T3885 prep of,as
R2401 T3887 T3886 pobj NFIL-6,of
R2402 T3888 T3887 prep to,NFIL-6
R2403 T3889 T3892 det the,oligonucleotides
R2404 T3890 T3892 amod corresponding,oligonucleotides
R2405 T3891 T3892 compound DNA,oligonucleotides
R2406 T3892 T3888 pobj oligonucleotides,to
R2407 T3893 T3895 punct (,consensus
R2408 T3894 T3895 nmod κ,consensus
R2409 T3895 T3892 appos consensus,oligonucleotides
R2410 T3896 T3895 punct ",",consensus
R2411 T3897 T3895 appos κ1,consensus
R2412 T3898 T3897 punct ",",κ1
R2413 T3899 T3897 conj κ2,κ1
R2414 T3900 T3895 punct ",",consensus
R2415 T3901 T3902 nummod κ3,sites
R2416 T3902 T3895 appos sites,consensus
R2417 T3903 T3902 prep from,sites
R2418 T3904 T3906 det the,promoter
R2419 T3905 T3906 compound TNFα,promoter
R2420 T3906 T3903 pobj promoter,from
R2421 T3907 T3895 punct ;,consensus
R2422 T3908 T3909 compound κ,consensus
R2423 T3909 T3875 dobj consensus,induced
R2424 T3910 T3909 prep from,consensus
R2425 T3911 T3913 det the,promoter
R2426 T3912 T3913 compound IL-8,promoter
R2427 T3913 T3910 pobj promoter,from
R2428 T3914 T3925 punct ;,1A
R2429 T3915 T3925 ccomp NFIL-6consensus,1A
R2430 T3916 T3915 prep from,NFIL-6consensus
R2431 T3917 T3919 det the,promoter
R2432 T3918 T3919 compound IL-6,promoter
R2433 T3919 T3916 pobj promoter,from
R2434 T3920 T3915 punct ;,NFIL-6consensus
R2435 T3921 T3925 npadvmod Table,1A
R2436 T3922 T3921 nummod 1,Table
R2437 T3923 T3925 punct ;,1A
R2438 T3924 T3925 compound Fig.,1A
R2439 T3925 T3925 ROOT 1A,1A
R2440 T3926 T3925 punct ),1A
R2441 T3927 T3925 punct .,1A
R2442 T3928 T3929 det The,extent
R2443 T3929 T3937 nsubj extent,was
R2444 T3930 T3929 prep of,extent
R2445 T3931 T3933 det the,shifts
R2446 T3932 T3933 compound band,shifts
R2447 T3933 T3930 pobj shifts,of
R2448 T3934 T3933 acl induced,shifts
R2449 T3935 T3934 agent by,induced
R2450 T3936 T3935 pobj GP,by
R2451 T3937 T3937 ROOT was,was
R2452 T3938 T3937 neg not,was
R2453 T3939 T3940 advmod statistically,different
R2454 T3940 T3937 acomp different,was
R2455 T3941 T3942 advmod when,compared
R2456 T3942 T3937 advcl compared,was
R2457 T3943 T3942 prep to,compared
R2458 T3944 T3943 pobj LPS,to
R2459 T3945 T3944 cc or,LPS
R2460 T3946 T3944 conj TSST-1,LPS
R2461 T3947 T3949 punct (,1B
R2462 T3948 T3949 compound Fig.,1B
R2463 T3949 T3946 appos 1B,TSST-1
R2464 T3950 T3949 punct ),1B
R2465 T3951 T3937 punct .,was
R2466 T3952 T3953 det A,supershift
R2467 T3953 T3966 nsubj supershift,demonstrated
R2468 T3954 T3953 punct ",",supershift
R2469 T3955 T3953 acl conducted,supershift
R2470 T3956 T3955 prep for,conducted
R2471 T3957 T3960 det an,site
R2472 T3958 T3960 compound NFκB,site
R2473 T3959 T3960 compound consensus,site
R2474 T3960 T3956 pobj site,for
R2475 T3961 T3955 prep from,conducted
R2476 T3962 T3964 det the,promoter
R2477 T3963 T3964 compound IL-8,promoter
R2478 T3964 T3961 pobj promoter,from
R2479 T3965 T3953 punct ",",supershift
R2480 T3966 T3966 ROOT demonstrated,demonstrated
R2481 T3967 T3970 det a,binding
R2482 T3968 T3969 amod GP-induced,predominant
R2483 T3969 T3970 amod predominant,binding
R2484 T3970 T3966 dobj binding,demonstrated
R2485 T3971 T3970 prep of,binding
R2486 T3972 T3971 pobj NFκB,of
R2487 T3973 T3972 nummod p65,NFκB
R2488 T3974 T3966 cc and,demonstrated
R2489 T3975 T3966 conj to,demonstrated
R2490 T3976 T3978 det a,degree
R2491 T3977 T3978 amod lesser,degree
R2492 T3978 T3975 pobj degree,to
R2493 T3979 T3978 prep of,degree
R2494 T3980 T3979 pobj p50,of
R2495 T3981 T3983 punct (,1A
R2496 T3982 T3983 compound Fig.,1A
R2497 T3983 T3978 appos 1A,degree
R2498 T3984 T3966 punct ),demonstrated
R2499 T3985 T3966 punct .,demonstrated
R2500 T3986 T3996 advmod Accordingly,showed
R2501 T3987 T3996 punct ",",showed
R2502 T3988 T3989 det an,immunoblot
R2503 T3989 T3996 nsubj immunoblot,showed
R2504 T3990 T3989 prep of,immunoblot
R2505 T3991 T3992 amod nuclear,extracts
R2506 T3992 T3990 pobj extracts,of
R2507 T3993 T3992 prep from,extracts
R2508 T3994 T3995 compound GP-treated,PBMC
R2509 T3995 T3993 pobj PBMC,from
R2510 T3996 T3996 ROOT showed,showed
R2511 T3997 T3999 det a,binding
R2512 T3998 T3999 amod strong,binding
R2513 T3999 T3996 dobj binding,showed
R2514 T4000 T3999 prep of,binding
R2515 T4001 T4000 pobj NFκB,of
R2516 T4002 T4001 nummod p65,NFκB
R2517 T4003 T3999 cc and,binding
R2518 T4004 T4006 det a,reaction
R2519 T4005 T4006 amod weaker,reaction
R2520 T4006 T3999 conj reaction,binding
R2521 T4007 T4006 prep of,reaction
R2522 T4008 T4007 pobj p50,of
R2523 T4009 T3996 punct ",",showed
R2524 T4010 T4012 mark whereas,was
R2525 T4011 T4012 nsubj p52,was
R2526 T4012 T3996 advcl was,showed
R2527 T4013 T4012 acomp negative,was
R2528 T4014 T4017 punct (,)
R2529 T4015 T4017 nmod Fig.,)
R2530 T4016 T4015 nummod 2,Fig.
R2531 T4017 T3996 punct ),showed
R2532 T4018 T3996 punct .,showed
R2533 T4019 T4020 amod Simultaneous,co-treatment
R2534 T4020 T4027 nsubj co-treatment,change
R2535 T4021 T4020 prep of,co-treatment
R2536 T4022 T4021 pobj PBMC,of
R2537 T4023 T4020 prep with,co-treatment
R2538 T4024 T4023 pobj GP,with
R2539 T4025 T4027 aux did,change
R2540 T4026 T4027 neg not,change
R2541 T4027 T4027 ROOT change,change
R2542 T4028 T4030 det the,NFκB
R2543 T4029 T4030 amod LPS-induced,NFκB
R2544 T4030 T4027 dobj NFκB,change
R2545 T4031 T4027 oprd binding,change
R2546 T4032 T4031 prep to,binding
R2547 T4033 T4032 pobj oligos,to
R2548 T4034 T4027 prep from,change
R2549 T4035 T4037 det the,promoter
R2550 T4036 T4037 compound TNFα,promoter
R2551 T4037 T4034 pobj promoter,from
R2552 T4038 T4027 advmod significantly,change
R2553 T4039 T4027 punct (,change
R2554 T4040 T4041 compound Fig.,1B
R2555 T4041 T4027 dobj 1B,change
R2556 T4042 T4027 punct ),change
R2557 T4043 T4027 punct ",",change
R2558 T4044 T4027 cc but,change
R2559 T4045 T4046 advmod substantially,decreased
R2560 T4046 T4050 amod decreased,binding
R2561 T4047 T4049 det the,NFκB
R2562 T4048 T4049 amod TSST-1-induced,NFκB
R2563 T4049 T4050 nsubj NFκB,binding
R2564 T4050 T4027 conj binding,change
R2565 T4051 T4052 advmod when,compared
R2566 T4052 T4063 advcl compared,differed
R2567 T4053 T4052 prep to,compared
R2568 T4054 T4053 pobj TSST-1,to
R2569 T4055 T4054 cc or,TSST-1
R2570 T4056 T4054 conj GP,TSST-1
R2571 T4057 T4059 punct (,μg
R2572 T4058 T4059 nummod 100,μg
R2573 T4059 T4056 appos μg,GP
R2574 T4060 T4059 punct ),μg
R2575 T4061 T4056 cc and,GP
R2576 T4062 T4063 advmod thus,differed
R2577 T4063 T4027 conj differed,change
R2578 T4064 T4063 advmod completely,differed
R2579 T4065 T4063 prep from,differed
R2580 T4066 T4068 det the,value
R2581 T4067 T4068 amod theoretical,value
R2582 T4068 T4065 pobj value,from
R2583 T4069 T4068 prep of,value
R2584 T4070 T4072 nmod GP/TSST,calc
R2585 T4071 T4072 nummod -1,calc
R2586 T4072 T4069 pobj calc,of
R2587 T4073 T4063 punct .,differed
R2588 T4074 T4077 punct (,4
R2589 T4075 T4077 advmod n,4
R2590 T4076 T4077 punct =,4
R2591 T4077 T4079 meta 4,p
R2592 T4078 T4079 punct ;,p
R2593 T4079 T4079 ROOT p,p
R2594 T4080 T4081 compound <,0.05
R2595 T4081 T4079 dobj 0.05,p
R2596 T4082 T4085 dep vs.,calc
R2597 T4083 T4085 nsubj GP/TSST,calc
R2598 T4084 T4085 nummod -1,calc
R2599 T4085 T4085 ROOT calc,calc
R2600 T4086 T4085 punct .,calc
R2601 T4087 T4088 cc and,p
R2602 T4088 T4088 ROOT p,p
R2603 T4089 T4090 punct =,0.07
R2604 T4090 T4088 nummod 0.07,p
R2605 T4091 T4088 prep vs.,p
R2606 T4092 T4091 pobj TSST-1,vs.
R2607 T4093 T4095 punct ;,1B
R2608 T4094 T4095 compound Fig.,1B
R2609 T4095 T4088 appos 1B,p
R2610 T4096 T4095 punct ),1B
R2611 T4097 T4088 punct .,p
R2612 T4098 T4099 nsubj GP,was
R2613 T4099 T4099 ROOT was,was
R2614 T4100 T4099 advmod also,was
R2615 T4101 T4099 acomp able,was
R2616 T4102 T4103 aux to,induce
R2617 T4103 T4101 xcomp induce,able
R2618 T4104 T4105 compound band,shifts
R2619 T4105 T4103 dobj shifts,induce
R2620 T4106 T4103 oprd indicative,induce
R2621 T4107 T4106 prep of,indicative
R2622 T4108 T4107 pobj binding,of
R2623 T4109 T4108 prep of,binding
R2624 T4110 T4111 amod particular,variants
R2625 T4111 T4109 pobj variants,of
R2626 T4112 T4111 prep of,variants
R2627 T4113 T4112 pobj NFAT,of
R2628 T4114 T4103 prep to,induce
R2629 T4115 T4116 det an,oligo
R2630 T4116 T4114 pobj oligo,to
R2631 T4117 T4116 prep from,oligo
R2632 T4118 T4120 det the,promoter
R2633 T4119 T4120 compound IFNγ,promoter
R2634 T4120 T4117 pobj promoter,from
R2635 T4121 T4120 punct (,promoter
R2636 T4122 T4123 compound Fig.,1A
R2637 T4123 T4120 appos 1A,promoter
R2638 T4124 T4120 punct ),promoter
R2639 T4125 T4099 punct .,was
R2640 T4126 T4127 det An,immunoblot
R2641 T4127 T4132 nsubj immunoblot,demonstrated
R2642 T4128 T4127 prep for,immunoblot
R2643 T4129 T4131 nummod two,subunits
R2644 T4130 T4131 compound NFAT,subunits
R2645 T4131 T4128 pobj subunits,for
R2646 T4132 T4132 ROOT demonstrated,demonstrated
R2647 T4133 T4135 det a,binding
R2648 T4134 T4135 amod GP-induced,binding
R2649 T4135 T4132 dobj binding,demonstrated
R2650 T4136 T4135 prep of,binding
R2651 T4137 T4136 pobj NFATc2,of
R2652 T4138 T4132 cc and,demonstrated
R2653 T4139 T4132 conj to,demonstrated
R2654 T4140 T4142 det a,degree
R2655 T4141 T4142 amod lesser,degree
R2656 T4142 T4139 pobj degree,to
R2657 T4143 T4142 prep of,degree
R2658 T4144 T4143 pobj NFATc1,of
R2659 T4145 T4144 punct (,NFATc1
R2660 T4146 T4144 appos Fig.,NFATc1
R2661 T4147 T4146 nummod 2,Fig.
R2662 T4148 T4144 punct ),NFATc1
R2663 T4149 T4132 punct .,demonstrated
R4031 T6522 T6523 compound Cytokine,profile
R4033 T6523 T6523 ROOT profile,profile
R4034 T6524 T6523 prep of,profile
R4035 T6525 T6526 compound human,PBMC
R4036 T6526 T6524 pobj PBMC,of
R4037 T6527 T6523 prep following,profile
R4038 T6528 T6530 det a,h
R4039 T6540 T6539 punct ",",GP
R4040 T6529 T6530 nummod 48,h
R4041 T6541 T6543 compound GP,LPS
R4042 T6542 T6543 compound +,LPS
R4043 T6543 T6539 conj LPS,GP
R4044 T6530 T6527 pobj h,following
R4045 T6544 T6543 cc and,LPS
R4046 T6545 T6547 compound GP,TSST-1
R4047 T6531 T6530 prep in,h
R4048 T6546 T6547 compound +,TSST-1
R4049 T6547 T6543 conj TSST-1,LPS
R4050 T6548 T6571 prep Because,assumed
R4051 T6532 T6533 amod vitro,stimulation
R4052 T6549 T6548 pcomp of,Because
R4053 T6550 T6553 det the,shifts
R4054 T6551 T6553 amod GP-induced,shifts
R4055 T6533 T6531 pobj stimulation,in
R4056 T6552 T6553 compound band,shifts
R4057 T6553 T6548 pobj shifts,Because
R4058 T6554 T6553 prep to,shifts
R4059 T6534 T6530 prep with,h
R4060 T6555 T6556 nummod seven,sites
R4061 T6556 T6554 pobj sites,to
R4062 T6557 T6556 prep from,sites
R4063 T6535 T6534 pobj LPS,with
R4064 T6558 T6559 det the,TNFα
R4065 T6559 T6557 pobj TNFα,from
R4066 T6560 T6559 punct ",",TNFα
R4067 T6536 T6535 punct ",",LPS
R4068 T6561 T6559 conj IL-8,TNFα
R4069 T6562 T6561 punct ",",IL-8
R4070 T6563 T6561 conj IL-6,IL-8
R4071 T6564 T6563 cc and,IL-6
R4072 T6537 T6535 conj TSST-1,LPS
R4073 T6565 T6563 conj IFNγ,IL-6
R4074 T6566 T6557 pobj promoters,from
R4075 T6567 T6571 punct ",",assumed
R4076 T6538 T6537 punct ",",TSST-1
R4077 T6568 T6571 nsubjpass it,assumed
R4078 T6569 T6571 aux could,assumed
R4079 T6570 T6571 auxpass be,assumed
R4080 T6539 T6537 conj GP,TSST-1
R4081 T6571 T6571 ROOT assumed,assumed
R4082 T6572 T6579 mark that,lead
R4083 T6573 T6574 compound GP,treatment
R4084 T6574 T6579 nsubj treatment,lead
R4085 T6637 T6638 amod inflammatory,cytokines
R4086 T6575 T6574 prep of,treatment
R4087 T6576 T6577 compound human,PBMC
R4088 T6577 T6575 pobj PBMC,of
R4089 T6578 T6579 aux would,lead
R4090 T6579 T6571 ccomp lead,assumed
R4091 T6580 T6579 prep to,lead
R4092 T6581 T6580 pobj production,to
R4093 T6582 T6581 prep of,production
R4094 T6638 T6625 dobj cytokines,examining
R4095 T6583 T6582 pobj TNFα,of
R4096 T6584 T6583 punct ",",TNFα
R4097 T6585 T6583 conj IL-8,TNFα
R4098 T6586 T6585 punct ",",IL-8
R4099 T6639 T6625 prep over,examining
R4100 T6587 T6585 conj IL-6,IL-8
R4101 T6588 T6587 punct ",",IL-6
R4102 T6589 T6587 conj IFNγ,IL-6
R4103 T6640 T6639 pobj time,over
R4104 T6590 T6589 cc and,IFNγ
R4105 T6591 T6593 amod other,mediators
R4106 T6592 T6593 amod pro-inflammatory,mediators
R4107 T6593 T6589 conj mediators,IFNγ
R4108 T6641 T6643 punct (,h
R4109 T6594 T6571 punct .,assumed
R4110 T6595 T6596 amod Previous,studies
R4111 T6642 T6643 nummod 48,h
R4112 T6596 T6597 nsubj studies,reported
R4113 T6597 T6597 ROOT reported,reported
R4114 T6598 T6602 mark that,induced
R4115 T6599 T6601 amod β-1,3-D-glucans
R4116 T6643 T6651 nmod h,sites
R4117 T6600 T6601 compound →,3-D-glucans
R4118 T6601 T6602 nsubj 3-D-glucans,induced
R4119 T6602 T6597 ccomp induced,reported
R4120 T6644 T6643 punct ),h
R4121 T6603 T6607 advmod only,secretion
R4122 T6604 T6607 det a,secretion
R4123 T6605 T6607 amod limited,secretion
R4124 T6645 T6643 cc and,h
R4125 T6606 T6607 compound cytokine,secretion
R4126 T6607 T6602 dobj secretion,induced
R4127 T6608 T6607 prep of,secretion
R4128 T6646 T6649 nummod six,factor
R4129 T6609 T6611 amod human,cells
R4130 T6647 T6649 amod additional,factor
R4131 T6610 T6611 compound blood,cells
R4132 T6611 T6608 pobj cells,of
R4133 T6648 T6649 compound transcription,factor
R4134 T6612 T6614 compound [,]
R4135 T6613 T6614 compound 15-18,]
R4136 T6614 T6607 appos ],secretion
R4137 T6649 T6651 nmod factor,sites
R4138 T6650 T6651 amod binding,sites
R4139 T6615 T6597 punct .,reported
R4140 T6616 T6656 advcl Corroborating,revealed
R4141 T6651 T6625 conj sites,examining
R4142 T6617 T6616 cc and,Corroborating
R4143 T6618 T6616 conj extending,Corroborating
R4144 T6652 T6656 punct ",",revealed
R4145 T6619 T6621 det these,findings
R4146 T6620 T6621 amod singular,findings
R4147 T6621 T6618 dobj findings,extending
R4148 T6653 T6655 poss our,analysis
R4149 T6622 T6618 prep in,extending
R4150 T6623 T6622 pobj terms,in
R4151 T6624 T6623 prep of,terms
R4152 T6654 T6655 amod comprehensive,analysis
R4153 T6625 T6624 pcomp examining,of
R4154 T6626 T6625 dobj pro-,examining
R4155 T6627 T6626 punct (,pro-
R4156 T6628 T6626 appos eight,pro-
R4157 T6655 T6656 nsubj analysis,revealed
R4158 T6629 T6626 punct ),pro-
R4159 T6630 T6632 advmod as,as
R4160 T6631 T6632 advmod well,as
R4161 T6656 T6656 ROOT revealed,revealed
R4162 T6632 T6633 nummod as,anti-
R4163 T6633 T6625 advcl anti-,examining
R4164 T6657 T6660 det the,profile
R4165 T6634 T6635 punct (,three
R4166 T6635 T6633 appos three,anti-
R4167 T6636 T6635 punct ),three
R4168 T6658 T6660 amod following,profile
R4169 T6659 T6660 compound cytokine,profile
R4170 T6660 T6656 dobj profile,revealed
R4171 T6661 T6660 prep of,profile
R4172 T6734 T6733 prep in,reduction
R4173 T6735 T6734 pobj IL-1β,in
R4174 T6662 T6663 amod human,leukocytes
R4175 T6736 T6733 prep from,reduction
R4176 T6737 T6738 nummod 18,h
R4177 T6663 T6661 pobj leukocytes,of
R4178 T6738 T6736 pobj h,from
R4179 T6739 T6740 nummod 24,h
R4180 T6740 T6738 appos h,h
R4181 T6664 T6656 prep in,revealed
R4182 T6741 T6740 punct ",",h
R4183 T6742 T6740 prep for,h
R4184 T6665 T6664 pobj response,in
R4185 T6743 T6744 det the,latter
R4186 T6744 T6742 pobj latter,for
R4187 T6745 T6740 prep by,h
R4188 T6746 T6747 advmod about,40
R4189 T6747 T6748 nummod 40,%
R4190 T6748 T6745 pobj %,by
R4191 T6666 T6665 prep to,response
R4192 T6749 T6750 advmod when,compared
R4193 T6750 T6730 advcl compared,found
R4194 T6751 T6750 prep to,compared
R4195 T6752 T6751 pobj TSST-1,to
R4196 T6667 T6674 det a,3-D-glucan
R4197 T6753 T6752 cc or,TSST-1
R4198 T6754 T6756 det the,value
R4199 T6668 T6669 advmod highly,purified
R4200 T6755 T6756 amod theoretical,value
R4201 T6756 T6752 conj value,TSST-1
R4202 T6757 T6756 prep of,value
R4203 T6669 T6674 amod purified,3-D-glucan
R4204 T6758 T6760 nmod GP/TSST,calc
R4205 T6759 T6760 nummod -1,calc
R4206 T6760 T6757 pobj calc,of
R4207 T6761 T6730 punct .,found
R4208 T6670 T6674 nmod water,3-D-glucan
R4209 T6762 T6765 punct (,6
R4210 T6763 T6765 advmod n,6
R4211 T6764 T6765 punct =,6
R4212 T6671 T6674 amod soluble,3-D-glucan
R4213 T6765 T6768 dep 6,p
R4214 T6766 T6768 punct ;,p
R4215 T6672 T6674 amod β-1,3-D-glucan
R4216 T6673 T6674 compound →,3-D-glucan
R4217 T6674 T6666 pobj 3-D-glucan,to
R4218 T6767 T6768 nsubj both,p
R4219 T6768 T6768 ROOT p,p
R4220 T6675 T6666 cc and,to
R4221 T6769 T6770 punct =,0.01
R4222 T6770 T6768 prep 0.01,p
R4223 T6676 T6656 prep in,revealed
R4224 T6771 T6768 punct ),p
R4225 T6772 T6768 punct .,p
R4226 T6773 T6778 prep On,mediated
R4227 T6774 T6775 det the,whole
R4228 T6677 T6676 pobj comparison,in
R4229 T6775 T6773 pobj whole,On
R4230 T6776 T6778 punct ",",mediated
R4231 T6678 T6677 prep to,comparison
R4232 T6777 T6778 nsubj GP,mediated
R4233 T6778 T6778 ROOT mediated,mediated
R4234 T6679 T6681 nummod two,mediators
R4235 T6779 T6780 det a,reduction
R4236 T6780 T6778 dobj reduction,mediated
R4237 T6781 T6780 prep of,reduction
R4238 T6782 T6784 det the,amount
R4239 T6783 T6784 compound TSST-1-induced,amount
R4240 T6784 T6781 pobj amount,of
R4241 T6785 T6784 prep of,amount
R4242 T6680 T6681 amod pro-inflammatory,mediators
R4243 T6786 T6785 pobj IL-1β,of
R4244 T6787 T6778 prep by,mediated
R4245 T6788 T6789 advmod about,50
R4246 T6681 T6678 pobj mediators,to
R4247 T6789 T6790 nummod 50,%
R4248 T6790 T6787 pobj %,by
R4249 T6791 T6793 punct (,3A
R4250 T6682 T6681 punct (,mediators
R4251 T6792 T6793 compound Fig.,3A
R4252 T6793 T6778 npadvmod 3A,mediated
R4253 T6794 T6778 punct ),mediated
R4254 T6683 T6681 appos LPS,mediators
R4255 T6795 T6778 punct .,mediated
R4256 T6796 T6797 punct (,ii
R4257 T6797 T6797 ROOT ii,ii
R4258 T6684 T6683 punct ",",LPS
R4259 T6798 T6797 punct ),ii
R4260 T6799 T6800 compound IL-6,GP
R4261 T6800 T6801 nsubj GP,induced
R4262 T6685 T6683 appos TSST-1,LPS
R4263 T6801 T6801 ROOT induced,induced
R4264 T6802 T6805 advmod only,amount
R4265 T6803 T6805 det a,amount
R4266 T6686 T6681 punct ),mediators
R4267 T6804 T6805 amod small,amount
R4268 T6805 T6801 dobj amount,induced
R4269 T6806 T6805 prep of,amount
R4270 T6687 T6681 punct :,mediators
R4271 T6807 T6806 pobj IL-6,of
R4272 T6808 T6801 cc and,induced
R4273 T6809 T6810 expl there,was
R4274 T6688 T6681 punct (,mediators
R4275 T6810 T6801 conj was,induced
R4276 T6811 T6813 det no,alteration
R4277 T6812 T6813 amod significant,alteration
R4278 T6813 T6810 attr alteration,was
R4279 T6814 T6813 prep of,alteration
R4280 T6689 T6681 appos i,mediators
R4281 T6815 T6818 det the,production
R4282 T6816 T6818 amod LPS-induced,production
R4283 T6817 T6818 compound IL-6,production
R4284 T6690 T6681 punct ),mediators
R4285 T6818 T6814 pobj production,of
R4286 T6819 T6818 prep by,production
R4287 T6820 T6819 pobj GP,by
R4288 T6821 T6810 punct .,was
R4289 T6822 T6827 prep On,observed
R4290 T6823 T6824 det the,contrary
R4291 T6824 T6822 pobj contrary,On
R4292 T6691 T6692 amod IL-1β,There
R4293 T6825 T6827 punct ",",observed
R4294 T6826 T6827 nsubj we,observed
R4295 T6827 T6859 ccomp observed,p
R4296 T6828 T6831 det a,production
R4297 T6692 T6693 expl There,was
R4298 T6829 T6831 amod decreased,production
R4299 T6830 T6831 compound IL-6,production
R4300 T6693 T6656 ccomp was,revealed
R4301 T6694 T6697 det no,detectable
R4302 T6695 T6696 amod IL-1β,production
R4303 T6831 T6827 dobj production,observed
R4304 T6832 T6831 prep for,production
R4305 T6696 T6697 compound production,detectable
R4306 T6833 T6835 compound GP,TSST-1
R4307 T6834 T6835 compound +,TSST-1
R4308 T6835 T6832 pobj TSST-1,for
R4309 T6697 T6693 attr detectable,was
R4310 T6836 T6837 advmod when,compared
R4311 T6837 T6827 advcl compared,observed
R4312 T6838 T6837 prep to,compared
R4313 T6698 T6697 prep following,detectable
R4314 T6839 T6838 pobj TSST-1,to
R4315 T6840 T6839 cc or,TSST-1
R4316 T6841 T6843 nmod GP/TSST,calc.
R4317 T6842 T6843 nummod -1,calc.
R4318 T6699 T6700 compound PBMC,treatment
R4319 T6843 T6839 conj calc.,TSST-1
R4320 T6844 T6843 punct ",",calc.
R4321 T6845 T6846 advmod especially,at
R4322 T6700 T6698 pobj treatment,following
R4323 T6701 T6700 prep with,treatment
R4324 T6702 T6705 nummod 1,μg
R4325 T6846 T6837 prep at,compared
R4326 T6847 T6848 nummod 24,h
R4327 T6848 T6846 pobj h,at
R4328 T6703 T6702 cc nor,1
R4329 T6849 T6848 prep by,h
R4330 T6850 T6851 advmod about,40
R4331 T6851 T6852 nummod 40,%
R4332 T6704 T6702 conj 100,1
R4333 T6852 T6849 pobj %,by
R4334 T6853 T6856 punct (,5
R4335 T6705 T6706 compound μg,GP
R4336 T6854 T6856 advmod n,5
R4337 T6855 T6856 punct =,5
R4338 T6706 T6701 pobj GP,with
R4339 T6856 T6848 npadvmod 5,h
R4340 T6857 T6859 punct ;,p
R4341 T6858 T6859 nsubj both,p
R4342 T6859 T6859 ROOT p,p
R4343 T6860 T6861 punct =,0.02
R4344 T6861 T6859 prep 0.02,p
R4345 T6862 T6859 punct ),p
R4346 T6707 T6656 punct .,revealed
R4347 T6863 T6859 punct ",",p
R4348 T6864 T6865 punct (,data
R4349 T6865 T6859 parataxis data,p
R4350 T6708 T6710 det An,up-regulation
R4351 T6866 T6867 neg not,shown
R4352 T6867 T6865 acl shown,data
R4353 T6868 T6867 prep in,shown
R4354 T6869 T6868 pobj detail,in
R4355 T6709 T6710 amod insignificant,up-regulation
R4356 T6870 T6865 punct ),data
R4357 T6871 T6859 punct .,p
R4358 T6872 T6873 punct (,iii
R4359 T6710 T6719 nsubjpass up-regulation,observed
R4360 T6873 T6873 ROOT iii,iii
R4361 T6874 T6873 punct ),iii
R4362 T6711 T6710 prep of,up-regulation
R4363 T6875 T6877 intj IL-8,found
R4364 T6876 T6877 nsubj We,found
R4365 T6877 T6877 ROOT found,found
R4366 T6878 T6880 mark that,induced
R4367 T6712 T6713 compound IL-1β,production
R4368 T6879 T6880 nsubj GP,induced
R4369 T6880 T6877 ccomp induced,found
R4370 T6713 T6711 pobj production,of
R4371 T6881 T6884 det a,production
R4372 T6882 T6884 amod substantial,production
R4373 T6714 T6713 prep for,production
R4374 T6883 T6884 compound IL-8,production
R4375 T6884 T6880 dobj production,induced
R4376 T6885 T6880 punct ",",induced
R4377 T6886 T6880 prep in,induced
R4378 T6715 T6717 compound GP,LPS
R4379 T6887 T6886 pobj comparison,in
R4380 T6888 T6887 prep with,comparison
R4381 T6889 T6890 amod medium,control
R4382 T6716 T6717 compound +,LPS
R4383 T6890 T6888 pobj control,with
R4384 T6891 T6880 punct ",",induced
R4385 T6717 T6714 pobj LPS,for
R4386 T6892 T6893 advmod especially,at
R4387 T6893 T6880 prep at,induced
R4388 T6894 T6895 nummod 24,h
R4389 T6895 T6893 pobj h,at
R4390 T6896 T6899 punct (,13
R4391 T6897 T6899 advmod n,13
R4392 T6898 T6899 punct =,13
R4393 T6718 T6719 auxpass was,observed
R4394 T6899 T6895 appos 13,h
R4395 T6900 T6901 punct ;,p
R4396 T6901 T6901 ROOT p,p
R4397 T6902 T6903 compound <,0.01
R4398 T6719 T6719 ROOT observed,observed
R4399 T6903 T6901 npadvmod 0.01,p
R4400 T6904 T6901 punct ),p
R4401 T6905 T6901 punct .,p
R4402 T6720 T6719 prep in,observed
R4403 T6906 T6907 det A,combination
R4404 T6907 T6912 nsubj combination,resulted
R4405 T6908 T6907 prep of,combination
R4406 T6721 T6720 pobj comparison,in
R4407 T6909 T6908 pobj GP,of
R4408 T6910 T6909 cc and,GP
R4409 T6911 T6909 conj LPS,GP
R4410 T6722 T6721 prep with,comparison
R4411 T6912 T6912 ROOT resulted,resulted
R4412 T6913 T6912 prep in,resulted
R4413 T6914 T6916 det a,increase
R4414 T6723 T6722 pobj LPS,with
R4415 T6915 T6916 amod non-significant,increase
R4416 T6916 T6913 pobj increase,in
R4417 T6917 T6916 prep of,increase
R4418 T6724 T6719 punct .,observed
R4419 T6918 T6919 amod IL-8,production
R4420 T6919 T6917 pobj production,of
R4421 T6920 T6921 advmod when,compared
R4422 T6725 T6730 prep For,found
R4423 T6921 T6912 advcl compared,resulted
R4424 T6922 T6921 prep to,compared
R4425 T6923 T6922 pobj LPS,to
R4426 T6726 T6728 compound GP,TSST-1
R4427 T6727 T6728 compound +,TSST-1
R4428 T6728 T6725 pobj TSST-1,For
R4429 T6924 T6923 cc or,LPS
R4430 T6925 T6926 compound GP/LPS,calc
R4431 T6729 T6730 nsubj we,found
R4432 T6926 T6923 conj calc,LPS
R4433 T6927 T6912 punct .,resulted
R4434 T6730 T6730 ROOT found,found
R4435 T6731 T6733 det a,reduction
R4436 T6732 T6733 amod significant,reduction
R4437 T6928 T6929 expl There,was
R4438 T6929 T6929 ROOT was,was
R4439 T6930 T6932 det no,alteration
R4440 T6931 T6932 amod significant,alteration
R4441 T6932 T6929 attr alteration,was
R4442 T6733 T6730 dobj reduction,found
R4443 T6933 T6932 prep in,alteration
R4444 T6934 T6935 amod IL-8,production
R4445 T7025 T7026 amod synergistic,increase
R4446 T6935 T6933 pobj production,in
R4447 T6936 T6929 prep following,was
R4448 T7026 T7023 dobj increase,found
R4449 T6937 T6939 compound GP,TSST-1
R4450 T6938 T6939 compound +,TSST-1
R4451 T6939 T6936 dobj TSST-1,following
R4452 T7027 T7026 prep in,increase
R4453 T6940 T6941 advmod when,compared
R4454 T6941 T6929 advcl compared,was
R4455 T6942 T6941 prep to,compared
R4456 T7028 T7029 compound IL-1RA,production
R4457 T6943 T6942 pobj TSST-1,to
R4458 T6944 T6943 cc or,TSST-1
R4459 T6945 T6947 dep GP/TSST,calc
R4460 T7029 T7027 pobj production,in
R4461 T6946 T6947 nummod -1,calc
R4462 T6947 T6943 conj calc,TSST-1
R4463 T6948 T6929 punct .,was
R4464 T7030 T7026 prep from,increase
R4465 T6949 T6950 punct (,data
R4466 T6950 T6950 ROOT data,data
R4467 T7031 T7032 nummod 18,h
R4468 T6951 T6952 neg not,shown
R4469 T6952 T6950 acl shown,data
R4470 T6953 T6952 prep in,shown
R4471 T7032 T7030 pobj h,from
R4472 T6954 T6953 pobj detail,in
R4473 T6955 T6950 punct ),data
R4474 T6956 T6950 punct .,data
R4475 T7033 T7026 prep to,increase
R4476 T6957 T6958 punct (,iv
R4477 T6958 T6958 ROOT iv,iv
R4478 T6959 T6958 punct ),iv
R4479 T7034 T7035 nummod 48,h
R4480 T6960 T6965 nsubj IL-1RA,was
R4481 T6961 T6965 prep Besides,was
R4482 T6962 T6961 pobj IL-8,Besides
R4483 T7035 T7033 pobj h,to
R4484 T6963 T6965 punct ",",was
R4485 T6964 T6965 nsubj IL-1RA,was
R4486 T6965 T6965 ROOT was,was
R4487 T7036 T7035 punct ",",h
R4488 T6966 T6968 det the,mediator
R4489 T6967 T6968 amod only,mediator
R4490 T6968 T6965 attr mediator,was
R4491 T6969 T6971 nsubjpass which,produced
R4492 T6970 T6971 auxpass was,produced
R4493 T6971 T6968 relcl produced,mediator
R4494 T7037 T7038 advmod when,compared
R4495 T6972 T6971 prep in,produced
R4496 T6973 T6974 amod significant,quantities
R4497 T6974 T6972 pobj quantities,in
R4498 T7038 T7023 advcl compared,found
R4499 T6975 T6968 prep following,mediator
R4500 T6976 T6977 compound GP,treatment
R4501 T6977 T6975 pobj treatment,following
R4502 T7039 T7038 prep to,compared
R4503 T6978 T6975 punct ",",following
R4504 T6979 T6980 advmod especially,at
R4505 T6980 T6975 prep at,following
R4506 T7040 T7039 pobj TSST-1,to
R4507 T7041 T7042 punct (,for
R4508 T6981 T6982 nummod 24,h
R4509 T7042 T7038 prep for,compared
R4510 T6982 T6980 pobj h,at
R4511 T7043 T7042 pobj instance,for
R4512 T6983 T6986 punct (,14
R4513 T6984 T6986 advmod n,14
R4514 T6985 T6986 punct =,14
R4515 T7044 T7042 prep at,for
R4516 T6986 T6982 appos 14,h
R4517 T6987 T6991 punct ",",)
R4518 T6988 T6991 nmod p,)
R4519 T7045 T7046 nummod 24,h
R4520 T6989 T6988 dobj <,p
R4521 T6990 T6989 nummod 0.01,<
R4522 T6991 T6965 punct ),was
R4523 T6992 T6965 punct .,was
R4524 T7046 T7044 pobj h,at
R4525 T6993 T6994 advmod When,compared
R4526 T6994 T7007 advcl compared,alter
R4527 T7047 T7048 punct :,n
R4528 T6995 T6994 prep to,compared
R4529 T6996 T6997 compound LPS,stimulation
R4530 T6997 T6995 pobj stimulation,to
R4531 T7048 T7052 advcl n,p
R4532 T6998 T6997 cc or,stimulation
R4533 T6999 T7000 compound GP/LPS,calc.
R4534 T7000 T6997 conj calc.,stimulation
R4535 T7001 T7000 punct ",",calc.
R4536 T7049 T7050 punct =,6
R4537 T7050 T7048 dobj 6,n
R4538 T7002 T7004 compound GP,LPS
R4539 T7051 T7052 punct ;,p
R4540 T7003 T7004 compound +,LPS
R4541 T7004 T7007 nsubj LPS,alter
R4542 T7005 T7007 aux did,alter
R4543 T7006 T7007 neg not,alter
R4544 T7007 T7007 ROOT alter,alter
R4545 T7052 T7052 ROOT p,p
R4546 T7008 T7010 det the,course
R4547 T7009 T7010 amod kinetic,course
R4548 T7010 T7007 dobj course,alter
R4549 T7053 T7054 punct =,0.01
R4550 T7011 T7010 prep of,course
R4551 T7012 T7014 det the,production
R4552 T7013 T7014 compound IL-1RA,production
R4553 T7014 T7011 pobj production,of
R4554 T7054 T7052 npadvmod 0.01,p
R4555 T7015 T7007 punct .,alter
R4556 T7016 T7023 advmod However,found
R4557 T7055 T7052 punct ),p
R4558 T7017 T7023 punct ",",found
R4559 T7018 T7023 prep following,found
R4560 T7019 T7021 compound GP,TSST-1
R4561 T7020 T7021 compound +,TSST-1
R4562 T7056 T7052 cc or,p
R4563 T7021 T7018 pobj TSST-1,following
R4564 T7022 T7023 nsubj we,found
R4565 T7057 T7052 conj to,p
R4566 T7023 T7023 ROOT found,found
R4567 T7024 T7026 det a,increase
R4568 T7058 T7060 det the,value
R4569 T7059 T7060 amod theoretical,value
R4570 T7060 T7057 pobj value,to
R4571 T7061 T7060 prep of,value
R4572 T7122 T7121 prep between,correlation
R4573 T7123 T7122 pobj IL-8,between
R4574 T7062 T7064 nmod GP/TSST,calc
R4575 T7124 T7123 cc and,IL-8
R4576 T7063 T7064 nummod -1,calc
R4577 T7125 T7123 conj IL-1RA,IL-8
R4578 T7126 T7118 punct .,observed
R4579 T7127 T7130 advmod Moreover,found
R4580 T7064 T7061 pobj calc,of
R4581 T7128 T7130 punct ",",found
R4582 T7065 T7052 punct .,p
R4583 T7066 T7067 punct (,from
R4584 T7067 T7067 ROOT from,from
R4585 T7129 T7130 nsubj we,found
R4586 T7068 T7069 nummod 18,h
R4587 T7130 T7130 ROOT found,found
R4588 T7131 T7132 det this,correlation
R4589 T7069 T7067 pobj h,from
R4590 T7132 T7130 dobj correlation,found
R4591 T7133 T7134 aux to,be
R4592 T7134 T7130 ccomp be,found
R4593 T7135 T7134 acomp dose-dependent,be
R4594 T7136 T7134 punct ",",be
R4595 T7137 T7142 mark since,induced
R4596 T7070 T7067 prep to,from
R4597 T7138 T7139 nummod 100,μg
R4598 T7139 T7142 nsubj μg,induced
R4599 T7140 T7139 prep of,μg
R4600 T7071 T7072 nummod 36,h
R4601 T7141 T7140 pobj GP,of
R4602 T7142 T7134 advcl induced,be
R4603 T7143 T7144 amod larger,amounts
R4604 T7144 T7142 dobj amounts,induced
R4605 T7072 T7070 pobj h,to
R4606 T7145 T7144 prep of,amounts
R4607 T7146 T7145 pobj IL-8,of
R4608 T7073 T7067 punct ),from
R4609 T7147 T7146 cc and,IL-8
R4610 T7148 T7146 conj IL-1RA,IL-8
R4611 T7149 T7142 prep than,induced
R4612 T7074 T7067 punct .,from
R4613 T7150 T7151 nummod 1,μg
R4614 T7151 T7152 compound μg,GP
R4615 T7152 T7149 pobj GP,than
R4616 T7075 T7084 prep Over,elevated
R4617 T7153 T7152 punct (,GP
R4618 T7154 T7158 dep n,p
R4619 T7155 T7156 punct =,5
R4620 T7076 T7078 det the,course
R4621 T7156 T7154 prep 5,n
R4622 T7157 T7158 punct ",",p
R4623 T7077 T7078 compound time,course
R4624 T7078 T7075 pobj course,Over
R4625 T7158 T7159 compound p,≤
R4626 T7079 T7078 prep of,course
R4627 T7159 T7152 appos ≤,GP
R4628 T7160 T7159 appos 0.002,≤
R4629 T7080 T7081 nummod 48,h
R4630 T7161 T7152 punct ",",GP
R4631 T7162 T7152 appos r,GP
R4632 T7163 T7164 punct =,0.9
R4633 T7081 T7079 pobj h,of
R4634 T7164 T7162 nummod 0.9,r
R4635 T7165 T7162 cc and,r
R4636 T7082 T7084 punct ",",elevated
R4637 T7166 T7162 conj 0.98,r
R4638 T7167 T7166 punct ",",0.98
R4639 T7083 T7084 nsubj GP,elevated
R4640 T7168 T7162 conj respectively,r
R4641 T7169 T7152 punct ),GP
R4642 T7170 T7130 punct .,found
R4643 T7171 T7172 punct (,v
R4644 T7172 T7172 ROOT v,v
R4645 T7173 T7172 punct ),v
R4646 T7084 T7084 ROOT elevated,elevated
R4647 T7174 T7185 nsubj TNFα,yielded
R4648 T7175 T7185 prep With,yielded
R4649 T7176 T7175 pobj respect,With
R4650 T7085 T7087 det the,amount
R4651 T7177 T7176 prep to,respect
R4652 T7178 T7179 compound TNFα,production
R4653 T7179 T7177 pobj production,to
R4654 T7086 T7087 amod TSST-1-induced,amount
R4655 T7180 T7179 punct ",",production
R4656 T7181 T7182 nummod 100,μg
R4657 T7182 T7185 nsubj μg,yielded
R4658 T7183 T7182 prep of,μg
R4659 T7087 T7084 dobj amount,elevated
R4660 T7184 T7183 pobj GP,of
R4661 T7185 T7185 ROOT yielded,yielded
R4662 T7186 T7191 amod minor,amounts
R4663 T7088 T7087 prep of,amount
R4664 T7187 T7190 punct ",",distinguishable
R4665 T7188 T7190 advmod statistically,distinguishable
R4666 T7189 T7190 neg not,distinguishable
R4667 T7089 T7088 pobj IL-1RA,of
R4668 T7190 T7191 amod distinguishable,amounts
R4669 T7191 T7185 dobj amounts,yielded
R4670 T7192 T7185 punct ",",yielded
R4671 T7090 T7084 prep by,elevated
R4672 T7193 T7194 advmod when,compared
R4673 T7194 T7185 advcl compared,yielded
R4674 T7195 T7194 prep to,compared
R4675 T7091 T7092 advmod approximately,200
R4676 T7196 T7197 amod medium,control
R4677 T7197 T7195 pobj control,to
R4678 T7198 T7185 punct .,yielded
R4679 T7092 T7093 nummod 200,%
R4680 T7199 T7201 compound GP,LPS
R4681 T7200 T7201 compound +,LPS
R4682 T7201 T7204 nsubj LPS,change
R4683 T7093 T7090 pobj %,by
R4684 T7202 T7204 aux did,change
R4685 T7203 T7204 neg not,change
R4686 T7204 T7204 ROOT change,change
R4687 T7094 T7096 punct (,3B
R4688 T7205 T7207 det the,production
R4689 T7206 T7207 amod TNFα,production
R4690 T7207 T7204 dobj production,change
R4691 T7095 T7096 compound Fig.,3B
R4692 T7208 T7209 advmod when,compared
R4693 T7209 T7204 advcl compared,change
R4694 T7210 T7209 prep to,compared
R4695 T7211 T7212 compound LPS,supplementation
R4696 T7212 T7210 pobj supplementation,to
R4697 T7213 T7212 cc or,supplementation
R4698 T7214 T7215 compound GP/LPS,calc
R4699 T7096 T7084 npadvmod 3B,elevated
R4700 T7215 T7212 conj calc,supplementation
R4701 T7216 T7204 punct .,change
R4702 T7217 T7218 advmod When,combined
R4703 T7218 T7227 advcl combined,seemed
R4704 T7097 T7084 punct ),elevated
R4705 T7219 T7218 prep with,combined
R4706 T7220 T7219 pobj TSST-1,with
R4707 T7221 T7220 cc or,TSST-1
R4708 T7098 T7084 punct .,elevated
R4709 T7222 T7224 nmod GP/TSST,calc.
R4710 T7223 T7224 nummod -1,calc.
R4711 T7224 T7220 conj calc.,TSST-1
R4712 T7099 T7100 amod Positive,correlation
R4713 T7225 T7227 punct ",",seemed
R4714 T7100 T7100 ROOT correlation,correlation
R4715 T7101 T7100 prep between,correlation
R4716 T7102 T7103 amod GP-induced,IL-8
R4717 T7226 T7227 nsubj GP,seemed
R4718 T7227 T7244 ccomp seemed,p
R4719 T7103 T7106 nmod IL-8,productions
R4720 T7228 T7229 aux to,exert
R4721 T7229 T7227 xcomp exert,seemed
R4722 T7230 T7232 det a,effect
R4723 T7104 T7103 cc and,IL-8
R4724 T7231 T7232 amod synergistic,effect
R4725 T7232 T7229 dobj effect,exert
R4726 T7233 T7232 prep on,effect
R4727 T7105 T7106 compound IL-1RA,productions
R4728 T7234 T7235 compound TNFα,secretion
R4729 T7235 T7233 pobj secretion,on
R4730 T7236 T7229 prep after,exert
R4731 T7106 T7101 pobj productions,between
R4732 T7107 T7100 punct .,correlation
R4733 T7237 T7238 nummod 36,h
R4734 T7108 T7118 prep Following,observed
R4735 T7238 T7236 pobj h,after
R4736 T7239 T7238 punct (,h
R4737 T7240 T7238 prep n,h
R4738 T7109 T7108 pobj stimulation,Following
R4739 T7241 T7242 punct =,3
R4740 T7242 T7240 pobj 3,n
R4741 T7243 T7244 punct ;,p
R4742 T7244 T7244 ROOT p,p
R4743 T7245 T7244 advmod <,p
R4744 T7246 T7244 npadvmod 0.05,p
R4745 T7110 T7109 prep with,stimulation
R4746 T7247 T7244 punct ),p
R4747 T7248 T7244 punct ",",p
R4748 T7249 T7244 cc but,p
R4749 T7111 T7110 pobj GP,with
R4750 T7250 T7252 advmod overall,enhancement
R4751 T7251 T7252 det an,enhancement
R4752 T7252 T7257 nsubj enhancement,was
R4753 T7112 T7114 punct (,h
R4754 T7253 T7252 prep of,enhancement
R4755 T7254 T7255 advmod only,10
R4756 T7255 T7256 nummod 10,%
R4757 T7113 T7114 nummod 24,h
R4758 T7256 T7253 pobj %,of
R4759 T7257 T7244 conj was,p
R4760 T7258 T7257 acomp observed,was
R4761 T7114 T7111 appos h,GP
R4762 T7259 T7264 punct (,data
R4763 T7260 T7261 compound p,>
R4764 T7261 T7264 nmod >,data
R4765 T7115 T7111 punct ),GP
R4766 T7262 T7261 nummod 0.05,>
R4767 T7263 T7264 punct ;,data
R4768 T7264 T7258 npadvmod data,observed
R4769 T7116 T7118 punct ",",observed
R4770 T7265 T7266 neg not,shown
R4771 T7266 T7264 acl shown,data
R4772 T7117 T7118 nsubj we,observed
R4773 T7267 T7266 prep in,shown
R4774 T7268 T7267 pobj detail,in
R4775 T7269 T7264 punct ),data
R4776 T7118 T7118 ROOT observed,observed
R4777 T7270 T7257 punct .,was
R4778 T7271 T7272 punct (,vi
R4779 T7272 T7272 ROOT vi,vi
R4780 T7119 T7121 det a,correlation
R4781 T7273 T7272 punct ),vi
R4782 T7274 T7277 compound IFNγ,production
R4783 T7275 T7277 compound No,production
R4784 T7276 T7277 compound IFNγ,production
R4785 T7120 T7121 amod positive,correlation
R4786 T7277 T7278 nsubj production,was
R4787 T7278 T7278 ROOT was,was
R4788 T7121 T7118 dobj correlation,observed
R4789 T7279 T7278 acomp detectable,was
R4790 T7280 T7278 prep following,was
R4791 T7281 T7280 dobj treatment,following
R4792 T7282 T7281 prep of,treatment
R4793 T7283 T7282 pobj PBMC,of
R4794 T7284 T7280 prep with,following
R4795 T7323 T7321 pobj h,at
R4796 T7285 T7286 nummod 100,μg
R4797 T7286 T7287 compound μg,GP
R4798 T7287 T7284 pobj GP,with
R4799 T7288 T7278 punct .,was
R4800 T7289 T7290 expl There,was
R4801 T7324 T7323 cc and,h
R4802 T7290 T7290 ROOT was,was
R4803 T7291 T7293 det a,increase
R4804 T7292 T7293 amod minor,increase
R4805 T7325 T7326 nummod 36,h
R4806 T7293 T7290 attr increase,was
R4807 T7294 T7293 prep in,increase
R4808 T7295 T7296 compound IFNγ,production
R4809 T7326 T7323 conj h,h
R4810 T7296 T7294 pobj production,in
R4811 T7297 T7293 prep following,increase
R4812 T7298 T7300 compound GP,LPS
R4813 T7299 T7300 compound +,LPS
R4814 T7327 T7326 punct ",",h
R4815 T7300 T7297 pobj LPS,following
R4816 T7301 T7293 prep at,increase
R4817 T7302 T7303 nummod 36,h
R4818 T7328 T7329 advmod when,compared
R4819 T7303 T7301 pobj h,at
R4820 T7304 T7303 punct ",",h
R4821 T7329 T7290 advcl compared,was
R4822 T7305 T7306 advmod when,compared
R4823 T7306 T7290 advcl compared,was
R4824 T7307 T7306 prep to,compared
R4825 T7308 T7307 pobj LPS,to
R4826 T7330 T7329 prep to,compared
R4827 T7309 T7308 cc or,LPS
R4828 T7310 T7311 compound GP/LPS,calc.
R4829 T7311 T7308 conj calc.,LPS
R4830 T7331 T7330 pobj TSST-1,to
R4831 T7312 T7311 punct ",",calc.
R4832 T7313 T7306 cc and,compared
R4833 T7314 T7316 det a,down-regulation
R4834 T7332 T7331 cc or,TSST-1
R4835 T7315 T7316 amod slight,down-regulation
R4836 T7333 T7335 dep GP/TSST,calc
R4837 T7316 T7306 conj down-regulation,compared
R4838 T7334 T7335 nummod -1,calc
R4839 T7317 T7316 acl following,down-regulation
R4840 T7318 T7320 compound GP,TSST-1
R4841 T7335 T7331 conj calc,TSST-1
R4842 T7319 T7320 compound +,TSST-1
R4843 T7320 T7317 pobj TSST-1,following
R4844 T7321 T7317 prep at,following
R4845 T7322 T7323 nummod 24,h
R4846 T7336 T7290 punct .,was
R4847 T7337 T7338 punct (,data
R4848 T7338 T7338 ROOT data,data
R4849 T7339 T7340 neg not,shown
R4850 T7340 T7338 acl shown,data
R4851 T7341 T7338 punct ),data
R4852 T7342 T7338 punct .,data
R4853 T7343 T7344 punct (,vii
R4855 T7344 T7344 ROOT vii,vii
R4858 T7345 T7344 punct ),vii
R4860 T7346 T7346 ROOT IL-2,IL-2
R4862 T7347 T7346 punct ",",IL-2
R4865 T7348 T7346 conj IL-12,IL-2
R4867 T7349 T7348 punct ",",IL-12
R4869 T7350 T7348 conj IL-4,IL-12
R4871 T7351 T7350 punct ",",IL-4
R4874 T7352 T7350 conj IL-10,IL-4
R4876 T7353 T7352 punct ",",IL-10
R4879 T7354 T7352 conj TGFβ1,IL-10
R4880 T7355 T7356 det The,production
R4882 T7356 T7370 nsubjpass production,induced
R4883 T7357 T7356 prep of,production
R4884 T7358 T7357 pobj IL-2,of
R4886 T7359 T7358 punct ",",IL-2
R4888 T7360 T7358 conj IL-12,IL-2
R4891 T7361 T7360 punct ",",IL-12
R4894 T7362 T7360 conj IL-4,IL-12
R4897 T7363 T7362 punct ",",IL-4
R4900 T7364 T7362 conj IL-10,IL-4
R4901 T7365 T7364 cc and,IL-10
R4904 T7366 T7364 conj TGFβ,IL-10
R4906 T7367 T7366 nummod 1,TGFβ
R4910 T7368 T7370 auxpass was,induced
R4912 T7369 T7370 neg not,induced
R4914 T7370 T7370 ROOT induced,induced
R4918 T7371 T7370 agent by,induced
R4919 T7372 T7371 pobj GP,by
R4920 T7373 T7370 punct .,induced
R4923 T7374 T7375 expl There,were
R4927 T7375 T7375 ROOT were,were
R4930 T7376 T7375 advmod also,were
R4932 T7377 T7379 det no,differences
R4933 T7378 T7379 amod significant,differences
R4934 T7379 T7375 attr differences,were
R4935 T7380 T7379 prep between,differences
R4936 T7381 T7382 amod medium,control
R4937 T7382 T7380 pobj control,between
R4938 T7383 T7382 punct ",",control
R4939 T7384 T7382 conj LPS,control
R4940 T7385 T7384 punct ",",LPS
R4941 T7386 T7384 conj TSST-1,LPS
R4943 T7387 T7386 punct ",",TSST-1
R4944 T7388 T7386 conj GP,TSST-1
R4945 T7389 T7388 punct ",",GP
R4946 T7390 T7392 compound GP,LPS
R4947 T7391 T7392 compound +,LPS
R4949 T7392 T7388 conj LPS,GP
R4951 T7393 T7392 punct ",",LPS
R5710 T8794 T8794 ROOT Role,Role
R5711 T8795 T8794 prep of,Role
R5712 T8796 T8795 pobj NFκB,of
R5713 T8797 T8796 punct ",",NFκB
R5714 T8798 T8796 conj NFIL-6,NFκB
R5715 T8799 T8798 cc and,NFIL-6
R5716 T8800 T8798 conj NFAT,NFIL-6
R5717 T8801 T8796 amod binding,NFκB
R5718 T8802 T8801 prep in,binding
R5719 T8803 T8802 pobj LPS,in
R5720 T8804 T8794 punct -,Role
R5721 T8805 T8794 punct ",",Role
R5722 T8806 T8794 appos TSST-1,Role
R5723 T8807 T8806 punct -,TSST-1
R5724 T8808 T8806 punct ",",TSST-1
R5725 T8809 T8806 conj GP,TSST-1
R5726 T8810 T8821 punct -,expression
R5727 T8811 T8821 punct ",",expression
R5728 T8812 T8821 compound GP,expression
R5729 T8813 T8821 compound +,expression
R5730 T8814 T8821 nmod LPS,expression
R5731 T8815 T8814 punct -,LPS
R5732 T8816 T8814 cc and,LPS
R5733 T8817 T8821 compound GP,expression
R5734 T8818 T8821 compound +,expression
R5735 T8819 T8820 compound TSST-1-induced,IL-1RA
R5736 T8820 T8821 compound IL-1RA,expression
R5737 T8821 T8806 appos expression,TSST-1
R5738 T8822 T8821 prep by,expression
R5739 T8823 T8824 amod human,PBMC
R5740 T8824 T8822 pobj PBMC,by
R5741 T8825 T8827 mark Because,induced
R5742 T8826 T8827 nsubj GP,induced
R5743 T8827 T8827 ROOT induced,induced
R5744 T8828 T8829 compound band,shifts
R5745 T8829 T8827 dobj shifts,induced
R5746 T8830 T8827 prep to,induced
R5747 T8831 T8836 nmod NFκB,sites
R5748 T8832 T8831 punct ",",NFκB
R5749 T8833 T8831 conj NFIL-6,NFκB
R5750 T8834 T8833 cc and,NFIL-6
R5751 T8835 T8833 conj NFAT,NFIL-6
R5752 T8836 T8830 pobj sites,to
R5753 T8837 T8827 punct ",",induced
R5754 T8838 T8827 cc but,induced
R5755 T8839 T8847 det no,hypothesized
R5756 T8840 T8847 advcl TNFα,hypothesized
R5757 T8841 T8840 punct ",",TNFα
R5758 T8842 T8840 conj IL-6,TNFα
R5759 T8843 T8842 cc or,IL-6
R5760 T8844 T8842 conj IFNγ,IL-6
R5761 T8845 T8847 punct ",",hypothesized
R5762 T8846 T8847 nsubj we,hypothesized
R5763 T8847 T8827 conj hypothesized,induced
R5764 T8848 T8854 mark that,bind
R5765 T8849 T8852 det the,factors
R5766 T8850 T8852 amod activated,factors
R5767 T8851 T8852 compound transcription,factors
R5768 T8852 T8854 nsubj factors,bind
R5769 T8853 T8854 aux might,bind
R5770 T8854 T8847 ccomp bind,hypothesized
R5771 T8855 T8854 prep to,bind
R5772 T8856 T8855 pobj sites,to
R5773 T8857 T8856 prep in,sites
R5774 T8858 T8860 det the,promoter
R5775 T8859 T8860 compound IL-1RA,promoter
R5776 T8860 T8857 pobj promoter,in
R5777 T8861 T8847 punct .,hypothesized
R5778 T8862 T8863 nsubj We,investigated
R5779 T8863 T8863 ROOT investigated,investigated
R5780 T8864 T8865 advmod previoulsy,described
R5781 T8865 T8863 conj described,investigated
R5782 T8866 T8865 cc and,described
R5783 T8867 T8868 advmod newly,discovered
R5784 T8868 T8865 conj discovered,described
R5785 T8869 T8870 compound transcription,factor
R5786 T8870 T8886 cc factor,v.
R5787 T8871 T8872 amod binding,sites
R5788 T8872 T8870 dobj sites,factor
R5789 T8873 T8872 prep of,sites
R5790 T8874 T8876 det the,promoter
R5791 T8875 T8876 compound IL-1RA,promoter
R5792 T8876 T8873 pobj promoter,of
R5793 T8877 T8876 punct (,promoter
R5794 T8878 T8876 appos Table,promoter
R5795 T8879 T8878 nummod 1,Table
R5796 T8880 T8876 punct ),promoter
R5797 T8881 T8870 acl using,factor
R5798 T8882 T8883 det the,program
R5799 T8883 T8881 dobj program,using
R5800 T8884 T8883 appos OMIGA,program
R5801 T8885 T8886 punct (,v.
R5802 T8886 T8863 cc v.,investigated
R5803 T8887 T8886 pobj 1.1.3,v.
R5804 T8888 T8887 punct ",",1.1.3
R5805 T8889 T8890 compound Oxford,Molecular
R5806 T8890 T8887 appos Molecular,1.1.3
R5807 T8891 T8890 punct ",",Molecular
R5808 T8892 T8890 conj Oxford,Molecular
R5809 T8893 T8892 punct ",",Oxford
R5810 T8894 T8892 conj UK,Oxford
R5811 T8895 T8892 punct ),Oxford
R5812 T8896 T8863 punct .,investigated
R5813 T8897 T8898 det The,LPS
R5814 T8898 T8898 ROOT LPS,LPS
R5815 T8899 T8902 amod responsive,site
R5816 T8900 T8902 compound κB,site
R5817 T8901 T8902 compound consensus,site
R5818 T8902 T8898 appos site,LPS
R5819 T8903 T8902 prep of,site
R5820 T8904 T8903 pobj LRE-1,of
R5821 T8905 T8902 punct (,site
R5822 T8906 T8907 quantmod between,-84
R5823 T8907 T8902 appos -84,site
R5824 T8908 T8907 cc and,-84
R5825 T8909 T8907 conj -93,-84
R5826 T8910 T8902 punct ),site
R5827 T8911 T8914 npadvmod [,displayed
R5828 T8912 T8913 nummod 30,]
R5829 T8913 T8914 nsubj ],displayed
R5830 T8914 T8898 relcl displayed,LPS
R5831 T8915 T8916 compound band,shifts
R5832 T8916 T8914 dobj shifts,displayed
R5833 T8917 T8914 punct ",",displayed
R5834 T8918 T8914 cc but,displayed
R5835 T8919 T8921 det no,alterations
R5836 T8920 T8921 amod significant,alterations
R5837 T8921 T8898 dobj alterations,LPS
R5838 T8922 T8921 prep of,alterations
R5839 T8923 T8925 poss its,activity
R5840 T8924 T8925 amod binding,activity
R5841 T8925 T8922 pobj activity,of
R5842 T8926 T8934 punct ",",shown
R5843 T8927 T8934 advmod irrespective,shown
R5844 T8928 T8927 prep of,irrespective
R5845 T8929 T8930 det the,treatment
R5846 T8930 T8928 pobj treatment,of
R5847 T8931 T8934 punct (,shown
R5848 T8932 T8934 nsubjpass data,shown
R5849 T8933 T8934 neg not,shown
R5850 T8934 T8898 acl shown,LPS
R5851 T8935 T8934 punct ),shown
R5852 T8936 T8898 punct .,LPS
R5853 T8937 T8940 det A,site
R5854 T8938 T8940 amod new,site
R5855 T8939 T8940 compound κB3,site
R5856 T8940 T8955 nsubjpass site,induced
R5857 T8941 T8940 punct (,site
R5858 T8942 T8940 appos -100,site
R5859 T8943 T8942 cc and,-100
R5860 T8944 T8942 conj -130,-100
R5861 T8945 T8940 punct ),site
R5862 T8946 T8940 prep within,site
R5863 T8947 T8949 det the,[
R5864 T8948 T8949 compound LRE-1,[
R5865 T8949 T8946 pobj [,within
R5866 T8950 T8949 nummod 30,[
R5867 T8951 T8952 amod ],showed
R5868 T8952 T8955 csubjpass showed,induced
R5869 T8953 T8955 amod increased,induced
R5870 T8954 T8955 amod binding,induced
R5871 T8955 T8955 ROOT induced,induced
R5872 T8956 T8955 agent by,induced
R5873 T8957 T8956 pobj TSST-1,by
R5874 T8958 T8960 punct (,%
R5875 T8959 T8960 nummod +30,%
R5876 T8960 T8957 parataxis %,TSST-1
R5877 T8961 T8960 prep vs.,%
R5878 T8962 T8961 pobj control,vs.
R5879 T8963 T8960 punct ),%
R5880 T8964 T8955 punct ",",induced
R5881 T8965 T8955 cc but,induced
R5882 T8966 T8968 compound GP,up-regulated
R5883 T8967 T8968 compound co-treatment,up-regulated
R5884 T8968 T8988 nsubj up-regulated,induced
R5885 T8969 T8970 det the,LPS
R5886 T8970 T8968 appos LPS,up-regulated
R5887 T8971 T8973 punct (,%
R5888 T8972 T8973 nummod +65,%
R5889 T8973 T8970 parataxis %,LPS
R5890 T8974 T8973 prep vs.,%
R5891 T8975 T8974 pobj control,vs.
R5892 T8976 T8973 punct ),%
R5893 T8977 T8970 punct -,LPS
R5894 T8978 T8970 cc and,LPS
R5895 T8979 T8980 det the,TSST-1
R5896 T8980 T8970 conj TSST-1,LPS
R5897 T8981 T8983 punct (,%
R5898 T8982 T8983 nummod +110,%
R5899 T8983 T8980 parataxis %,TSST-1
R5900 T8984 T8983 prep vs.,%
R5901 T8985 T8984 pobj control,vs.
R5902 T8986 T8983 punct ),%
R5903 T8987 T8988 punct -,induced
R5904 T8988 T8955 conj induced,induced
R5905 T8989 T8988 advmod binding,induced
R5906 T8990 T8988 prep in,induced
R5907 T8991 T8994 det a,fashion
R5908 T8992 T8994 amod superadditive,fashion
R5909 T8993 T8994 amod synergistic,fashion
R5910 T8994 T8990 pobj fashion,in
R5911 T8995 T8994 punct ",",fashion
R5912 T8996 T8997 advmod when,compared
R5913 T8997 T8988 advcl compared,induced
R5914 T8998 T8997 prep to,compared
R5915 T8999 T9000 amod medium,control
R5916 T9000 T8998 pobj control,to
R5917 T9001 T9003 advmod as,as
R5918 T9002 T9003 advmod well,as
R5919 T9003 T8998 cc as,to
R5920 T9004 T9003 prep to,as
R5921 T9005 T9021 dep LPS,calc
R5922 T9006 T9005 punct ",",LPS
R5923 T9007 T9005 conj TSST-1,LPS
R5924 T9008 T9007 cc or,TSST-1
R5925 T9009 T9007 conj GP,TSST-1
R5926 T9010 T9009 cc or,GP
R5927 T9011 T9013 det the,values
R5928 T9012 T9013 amod theoretical,values
R5929 T9013 T9009 conj values,GP
R5930 T9014 T9013 prep of,values
R5931 T9015 T9016 compound GP/LPS,calc
R5932 T9016 T9014 pobj calc,of
R5933 T9017 T9013 punct .,values
R5934 T9018 T9013 cc or,values
R5935 T9019 T9021 nsubj GP/TSST,calc
R5936 T9020 T9021 nummod -1,calc
R5937 T9021 T9004 pobj calc,to
R5938 T9022 T8988 punct .,induced
R5939 T9023 T9029 punct (,Fig.
R5940 T9024 T9029 dep all,Fig.
R5941 T9025 T9029 ccomp p,Fig.
R5942 T9026 T9027 compound <,0.05
R5943 T9027 T9025 dobj 0.05,p
R5944 T9028 T9029 punct ;,Fig.
R5945 T9029 T9029 ROOT Fig.,Fig.
R5946 T9030 T9029 nummod 4,Fig.
R5947 T9031 T9029 punct ),Fig.
R5948 T9032 T9029 punct .,Fig.
R5949 T9033 T9048 nsubjpass Binding,elevated
R5950 T9034 T9033 prep to,Binding
R5951 T9035 T9039 det a,site
R5952 T9036 T9039 amod new,site
R5953 T9037 T9039 compound κB,site
R5954 T9038 T9039 compound consensus,site
R5955 T9039 T9034 pobj site,to
R5956 T9040 T9039 punct (,site
R5957 T9041 T9039 prep between,site
R5958 T9042 T9041 pobj -266,between
R5959 T9043 T9042 cc and,-266
R5960 T9044 T9042 conj -280,-266
R5961 T9045 T9039 punct ),site
R5962 T9046 T9048 auxpass was,elevated
R5963 T9047 T9048 advmod significantly,elevated
R5964 T9048 T9048 ROOT elevated,elevated
R5965 T9049 T9048 prep for,elevated
R5966 T9050 T9052 compound GP,TSST-1
R5967 T9051 T9052 compound +,TSST-1
R5968 T9052 T9049 pobj TSST-1,for
R5969 T9053 T9052 punct (,TSST-1
R5970 T9054 T9055 compound p,<
R5971 T9055 T9052 appos <,TSST-1
R5972 T9056 T9055 nummod 0.05,<
R5973 T9057 T9052 punct ;,TSST-1
R5974 T9058 T9049 pobj data,for
R5975 T9059 T9060 neg not,shown
R5976 T9060 T9058 acl shown,data
R5977 T9061 T9058 punct ),data
R5978 T9062 T9048 punct .,elevated
R5979 T9063 T9064 det The,LPS
R5980 T9064 T9087 nsubjpass LPS,down-regulated
R5981 T9065 T9064 punct -,LPS
R5982 T9066 T9064 punct ",",LPS
R5983 T9067 T9087 nsubjpass TSST-1,down-regulated
R5984 T9068 T9067 punct -,TSST-1
R5985 T9069 T9067 cc and,TSST-1
R5986 T9070 T9072 compound GP,LPS-induced
R5987 T9071 T9072 compound +,LPS-induced
R5988 T9072 T9086 nsubj LPS-induced,was
R5989 T9073 T9072 amod binding,LPS-induced
R5990 T9074 T9073 prep to,binding
R5991 T9075 T9080 det the,site
R5992 T9076 T9080 amod new,site
R5993 T9077 T9078 compound κB2,/
R5994 T9078 T9080 nmod /,site
R5995 T9079 T9078 nummod 3,/
R5996 T9080 T9074 pobj site,to
R5997 T9081 T9080 punct (,site
R5998 T9082 T9080 appos -288,site
R5999 T9083 T9080 cc and,site
R6000 T9084 T9080 conj -302,site
R6001 T9085 T9072 punct ),LPS-induced
R6002 T9086 T9087 auxpass was,down-regulated
R6003 T9087 T9087 ROOT down-regulated,down-regulated
R6004 T9088 T9087 prep by,down-regulated
R6005 T9089 T9090 advmod about,20
R6006 T9090 T9088 pobj 20,by
R6007 T9091 T9092 nummod 35,%
R6008 T9092 T9087 npadvmod %,down-regulated
R6009 T9093 T9087 prep in,down-regulated
R6010 T9094 T9093 pobj comparison,in
R6011 T9095 T9094 prep with,comparison
R6012 T9096 T9097 amod medium,control
R6013 T9097 T9095 pobj control,with
R6014 T9098 T9103 punct (,data
R6015 T9099 T9100 dep p,<
R6016 T9100 T9103 dep <,data
R6017 T9101 T9100 nummod 0.05,<
R6018 T9102 T9103 punct ;,data
R6019 T9103 T9097 appos data,control
R6020 T9104 T9105 neg not,shown
R6021 T9105 T9103 acl shown,data
R6022 T9106 T9103 punct ),data
R6023 T9107 T9087 punct .,down-regulated
R6024 T9108 T9110 det The,site
R6025 T9109 T9110 compound NFIL-6,site
R6026 T9110 T9122 nsubj site,showed
R6027 T9111 T9110 punct (,site
R6028 T9112 T9110 appos -147,site
R6029 T9113 T9112 cc and,-147
R6030 T9114 T9112 conj -170,-147
R6031 T9115 T9110 punct ),site
R6032 T9116 T9110 amod close,site
R6033 T9117 T9116 prep to,close
R6034 T9118 T9121 compound LRE-2,]
R6035 T9119 T9121 compound [,]
R6036 T9120 T9121 compound "31,32",]
R6037 T9121 T9117 pobj ],to
R6038 T9122 T9122 ROOT showed,showed
R6039 T9123 T9124 det an,up-regulation
R6040 T9124 T9122 dobj up-regulation,showed
R6041 T9125 T9124 prep of,up-regulation
R6042 T9126 T9125 pobj binding,of
R6043 T9127 T9126 prep for,binding
R6044 T9128 T9129 det all,compounds
R6045 T9129 T9127 pobj compounds,for
R6046 T9130 T9129 cc and,compounds
R6047 T9131 T9129 conj combinations,compounds
R6048 T9132 T9129 prep vs.,compounds
R6049 T9133 T9134 compound medium,control
R6050 T9134 T9132 pobj control,vs.
R6051 T9135 T9122 punct ",",showed
R6052 T9136 T9122 advcl ranging,showed
R6053 T9137 T9136 prep from,ranging
R6054 T9138 T9137 pobj 25,from
R6055 T9139 T9140 nummod 110,%
R6056 T9140 T9136 npadvmod %,ranging
R6057 T9141 T9144 punct (,0.05
R6058 T9142 T9143 nmod p,<
R6059 T9143 T9144 nmod <,0.05
R6060 T9144 T9140 appos 0.05,%
R6061 T9145 T9144 punct ),0.05
R6062 T9146 T9122 punct .,showed
R6063 T9147 T9152 advmod Further,induced
R6064 T9148 T9152 punct ",",induced
R6065 T9149 T9151 compound GP,TSST-1
R6066 T9150 T9151 compound +,TSST-1
R6067 T9151 T9152 nsubj TSST-1,induced
R6068 T9152 T9152 ROOT induced,induced
R6069 T9153 T9155 det an,binding
R6070 T9154 T9155 amod increased,binding
R6071 T9155 T9152 dobj binding,induced
R6072 T9156 T9152 prep to,induced
R6073 T9157 T9159 det the,site
R6074 T9158 T9159 compound NFIL-6,site
R6075 T9159 T9156 pobj site,to
R6076 T9160 T9152 prep in,induced
R6077 T9161 T9160 pobj comparison,in
R6078 T9162 T9161 prep with,comparison
R6079 T9163 T9166 nummod TSST-1,fold
R6080 T9164 T9166 punct (,fold
R6081 T9165 T9166 nummod 1.3,fold
R6082 T9166 T9152 advcl fold,induced
R6083 T9167 T9166 punct ),fold
R6084 T9168 T9166 cc or,fold
R6085 T9169 T9166 conj GP,fold
R6086 T9170 T9169 punct (,GP
R6087 T9171 T9172 nummod 1.6,fold
R6088 T9172 T9169 appos fold,GP
R6089 T9173 T9169 punct ;,GP
R6090 T9174 T9169 conj p,GP
R6091 T9175 T9176 compound <,0.05
R6092 T9176 T9174 dobj 0.05,p
R6093 T9177 T9174 punct ),p
R6094 T9178 T9169 punct ",",GP
R6095 T9179 T9169 punct (,GP
R6096 T9180 T9182 dative data,shown
R6097 T9181 T9182 neg not,shown
R6098 T9182 T9169 appos shown,GP
R6099 T9183 T9182 punct ),shown
R6100 T9184 T9152 punct .,induced
R6101 T9185 T9188 det A,site
R6102 T9186 T9188 amod new,site
R6103 T9187 T9188 amod binding,site
R6104 T9188 T9192 nsubjpass site,found
R6105 T9189 T9188 prep for,site
R6106 T9190 T9189 pobj NFATP2/3,for
R6107 T9191 T9192 auxpass was,found
R6108 T9192 T9192 ROOT found,found
R6109 T9193 T9194 advmod more,distal
R6110 T9194 T9192 oprd distal,found
R6111 T9195 T9194 prep of,distal
R6112 T9196 T9197 det the,transcription
R6113 T9197 T9195 pobj transcription,of
R6114 T9198 T9199 compound start,site
R6115 T9199 T9192 npadvmod site,found
R6116 T9200 T9199 punct ",",site
R6117 T9201 T9199 prep between,site
R6118 T9202 T9201 pobj -471,between
R6119 T9203 T9202 cc and,-471
R6120 T9204 T9202 conj -490,-471
R6121 T9205 T9192 punct ",",found
R6122 T9206 T9192 advcl displaying,found
R6123 T9207 T9206 advmod again,displaying
R6124 T9208 T9210 det a,increase
R6125 T9209 T9210 amod substantial,increase
R6126 T9210 T9206 dobj increase,displaying
R6127 T9211 T9210 prep of,increase
R6128 T9212 T9211 pcomp binding,of
R6129 T9213 T9212 prep for,binding
R6130 T9214 T9215 det all,compounds
R6131 T9215 T9213 pobj compounds,for
R6132 T9216 T9215 cc and,compounds
R6133 T9217 T9215 conj combinations,compounds
R6134 T9218 T9210 punct ",",increase
R6135 T9219 T9220 advmod when,compared
R6136 T9220 T9206 advcl compared,displaying
R6137 T9221 T9220 prep to,compared
R6138 T9222 T9223 amod medium,control
R6139 T9223 T9221 pobj control,to
R6140 T9224 T9227 punct (,0.05
R6141 T9225 T9226 nmod p,<
R6142 T9226 T9227 nmod <,0.05
R6143 T9227 T9223 appos 0.05,control
R6144 T9228 T9206 punct ),displaying
R6145 T9229 T9192 punct .,found
R6146 T9230 T9246 prep In,fold
R6147 T9231 T9230 pobj addition,In
R6148 T9232 T9246 punct ",",fold
R6149 T9233 T9238 amod binding,following
R6150 T9234 T9233 prep to,binding
R6151 T9235 T9237 det the,site
R6152 T9236 T9237 compound NFATP2/3,site
R6153 T9237 T9234 pobj site,to
R6154 T9238 T9246 amod following,fold
R6155 T9239 T9238 pobj both,following
R6156 T9240 T9239 punct ",",both
R6157 T9241 T9243 compound GP,LPS
R6158 T9242 T9243 compound +,LPS
R6159 T9243 T9238 dobj LPS,following
R6160 T9244 T9246 punct (,fold
R6161 T9245 T9246 nummod 1.4,fold
R6162 T9246 T9246 ROOT fold,fold
R6163 T9247 T9246 prep of,fold
R6164 T9248 T9247 pobj GP,of
R6165 T9249 T9246 punct ),fold
R6166 T9250 T9246 cc and,fold
R6167 T9251 T9253 compound GP,TSST-1
R6168 T9252 T9253 compound +,TSST-1
R6169 T9253 T9266 nsubjpass TSST-1,elevated
R6170 T9254 T9256 punct (,fold
R6171 T9255 T9256 nummod 1.5,fold
R6172 T9256 T9261 ccomp fold,fold
R6173 T9257 T9256 prep of,fold
R6174 T9258 T9257 pobj GP,of
R6175 T9259 T9258 punct ",",GP
R6176 T9260 T9261 nummod 1.25,fold
R6177 T9261 T9253 appos fold,TSST-1
R6178 T9262 T9261 prep of,fold
R6179 T9263 T9262 pobj TSST-1,of
R6180 T9264 T9253 punct ),TSST-1
R6181 T9265 T9266 auxpass was,elevated
R6182 T9266 T9246 conj elevated,fold
R6183 T9267 T9272 punct (,Fig.
R6184 T9268 T9269 compound p,<
R6185 T9269 T9272 ccomp <,Fig.
R6186 T9270 T9269 nummod 0.05,<
R6187 T9271 T9272 punct ;,Fig.
R6188 T9272 T9266 parataxis Fig.,elevated
R6189 T9273 T9272 nummod 5,Fig.
R6190 T9274 T9272 punct ),Fig.
R6191 T9275 T9266 punct ",",elevated
R6192 T9276 T9266 cc but,elevated
R6193 T9277 T9278 advmod only,in
R6194 T9278 T9288 prep in,were
R6195 T9279 T9282 det an,manner
R6196 T9280 T9282 amod additive,manner
R6197 T9281 T9282 amod synergistic,manner
R6198 T9282 T9278 pobj manner,in
R6199 T9283 T9288 punct ",",were
R6200 T9284 T9287 advmod i.e.,results
R6201 T9285 T9287 det the,results
R6202 T9286 T9287 amod experimental,results
R6203 T9287 T9288 nsubj results,were
R6204 T9288 T9266 conj were,elevated
R6205 T9289 T9288 neg not,were
R6206 T9290 T9288 acomp different,were
R6207 T9291 T9290 prep from,different
R6208 T9292 T9294 det the,values
R6209 T9293 T9294 amod theoretical,values
R6210 T9294 T9291 pobj values,from
R6211 T9295 T9296 punct (,calc
R6212 T9296 T9294 appos calc,values
R6213 T9297 T9288 punct .,were
R6214 T9298 T9288 punct ),were
R6215 T9299 T9246 punct .,fold
R6553 T10009 T10010 nsubj GP,modulated
R6554 T10010 T10010 ROOT modulated,modulated
R6555 T10011 T10016 det the,ratio
R6556 T10012 T10016 amod TSST-1-induced,ratio
R6557 T10013 T10016 amod IL-1β,ratio
R6558 T10014 T10016 nmod /,ratio
R6559 T10015 T10016 compound IL-1RA,ratio
R6560 T10016 T10010 dobj ratio,modulated
R6561 T10017 T10016 prep towards,ratio
R6562 T10018 T10020 det an,phenotype
R6563 T10019 T10020 amod anti-inflammatory,phenotype
R6564 T10020 T10017 pobj phenotype,towards
R6565 T10021 T10030 prep In,represent
R6566 T10022 T10024 det a,approach
R6567 T10023 T10024 amod simplified,approach
R6568 T10024 T10021 pobj approach,In
R6569 T10025 T10024 punct ",",approach
R6570 T10026 T10030 nsubj IL-1β,represent
R6571 T10027 T10026 cc and,IL-1β
R6572 T10028 T10026 conj IL-1RA,IL-1β
R6573 T10029 T10030 aux might,represent
R6574 T10030 T10030 ROOT represent,represent
R6575 T10031 T10032 nummod two,sides
R6576 T10032 T10030 dobj sides,represent
R6577 T10033 T10032 prep of,sides
R6578 T10034 T10035 det a,coin
R6579 T10035 T10033 pobj coin,of
R6580 T10036 T10032 punct ",",sides
R6581 T10037 T10038 advmod i.e.,pro-
R6582 T10038 T10041 amod pro-,action
R6583 T10039 T10038 cc or,pro-
R6584 T10040 T10038 conj anti-inflammatory,pro-
R6585 T10041 T10032 appos action,sides
R6586 T10042 T10030 punct .,represent
R6587 T10043 T10046 advmod Therefore,applied
R6588 T10044 T10046 punct ",",applied
R6589 T10045 T10046 nsubj we,applied
R6590 T10046 T10046 ROOT applied,applied
R6591 T10047 T10051 det the,ratio
R6592 T10048 T10051 amod IL-1β,ratio
R6593 T10049 T10051 nmod /,ratio
R6594 T10050 T10051 compound IL-1RA,ratio
R6595 T10051 T10046 dobj ratio,applied
R6596 T10052 T10046 prep as,applied
R6597 T10053 T10054 det an,indicator
R6598 T10054 T10052 pobj indicator,as
R6599 T10055 T10054 prep of,indicator
R6600 T10056 T10057 det the,degree
R6601 T10057 T10055 pobj degree,of
R6602 T10058 T10057 prep of,degree
R6603 T10059 T10058 pobj inflammation,of
R6604 T10060 T10046 punct .,applied
R6605 T10061 T10069 dep Both,resulted
R6606 T10062 T10069 punct ",",resulted
R6607 T10063 T10069 nsubj LPS,resulted
R6608 T10064 T10063 cc and,LPS
R6609 T10065 T10068 compound GP,treatments
R6610 T10066 T10068 compound +,treatments
R6611 T10067 T10068 compound LPS,treatments
R6612 T10068 T10063 conj treatments,LPS
R6613 T10069 T10184 ccomp resulted,p
R6614 T10070 T10069 prep in,resulted
R6615 T10071 T10070 pcomp generating,in
R6616 T10072 T10073 advmod more,IL-1β
R6617 T10073 T10071 dobj IL-1β,generating
R6618 T10074 T10073 prep than,IL-1β
R6619 T10075 T10074 pobj IL-1RA,than
R6620 T10076 T10071 prep at,generating
R6621 T10077 T10078 amod early,time
R6622 T10078 T10079 compound time,points
R6623 T10079 T10076 pobj points,at
R6624 T10080 T10096 punct ",",find
R6625 T10081 T10096 advmod i.e.,find
R6626 T10082 T10084 quantmod up,24
R6627 T10083 T10084 quantmod to,24
R6628 T10084 T10085 nummod 24,h.
R6629 T10085 T10096 npadvmod h.,find
R6630 T10086 T10096 advcl Comparing,find
R6631 T10087 T10086 dobj LPS,Comparing
R6632 T10088 T10091 nmod vs.,LPS
R6633 T10089 T10091 nmod GP,LPS
R6634 T10090 T10091 nmod +,LPS
R6635 T10091 T10086 npadvmod LPS,Comparing
R6636 T10092 T10096 punct ",",find
R6637 T10093 T10096 nsubj we,find
R6638 T10094 T10096 aux did,find
R6639 T10095 T10096 neg not,find
R6640 T10096 T10069 advcl find,resulted
R6641 T10097 T10098 amod substantial,alterations
R6642 T10098 T10096 dobj alterations,find
R6643 T10099 T10098 prep over,alterations
R6644 T10100 T10102 det a,course
R6645 T10101 T10102 compound time,course
R6646 T10102 T10099 pobj course,over
R6647 T10103 T10102 prep of,course
R6648 T10104 T10105 nummod 48,h
R6649 T10105 T10103 pobj h,of
R6650 T10106 T10105 prep in,h
R6651 T10107 T10111 det the,ratio
R6652 T10108 T10111 amod IL-1β,ratio
R6653 T10109 T10111 nmod /,ratio
R6654 T10110 T10111 compound IL-1RA,ratio
R6655 T10111 T10106 pobj ratio,in
R6656 T10112 T10111 punct ",",ratio
R6657 T10113 T10114 advmod only,a
R6658 T10114 T10115 det a,non-significant
R6659 T10115 T10111 appos non-significant,ratio
R6660 T10116 T10117 meta 2.5,fold
R6661 T10117 T10115 dep fold,non-significant
R6662 T10118 T10119 amod higher,ratio
R6663 T10119 T10117 dobj ratio,fold
R6664 T10120 T10117 prep at,fold
R6665 T10121 T10122 nummod 6,h.
R6666 T10122 T10120 pobj h.,at
R6667 T10123 T10122 prep With,h.
R6668 T10124 T10123 pobj respect,With
R6669 T10125 T10124 prep to,respect
R6670 T10126 T10125 pobj TSST-1,to
R6671 T10127 T10126 cc or,TSST-1
R6672 T10128 T10130 det the,value
R6673 T10129 T10130 amod theoretical,value
R6674 T10130 T10126 conj value,TSST-1
R6675 T10131 T10130 prep of,value
R6676 T10132 T10134 nmod GP/TSST,calc
R6677 T10133 T10134 nummod -1,calc
R6678 T10134 T10131 pobj calc,of
R6679 T10135 T10117 punct .,fold
R6680 T10136 T10115 prep vs.,non-significant
R6681 T10137 T10139 compound GP,TSST-1
R6682 T10138 T10139 compound +,TSST-1
R6683 T10139 T10136 pobj TSST-1,vs.
R6684 T10140 T10142 punct ",",observed
R6685 T10141 T10142 nsubj we,observed
R6686 T10142 T10184 ccomp observed,p
R6687 T10143 T10146 det a,action
R6688 T10144 T10146 amod pronounced,action
R6689 T10145 T10146 amod anti-inflammatory,action
R6690 T10146 T10142 dobj action,observed
R6691 T10147 T10146 prep of,action
R6692 T10148 T10147 pobj GP,of
R6693 T10149 T10142 punct ",",observed
R6694 T10150 T10151 mark as,demonstrated
R6695 T10151 T10142 advcl demonstrated,observed
R6696 T10152 T10151 agent by,demonstrated
R6697 T10153 T10155 det an,10
R6698 T10154 T10155 quantmod about,10
R6699 T10155 T10152 pobj 10,by
R6700 T10156 T10157 nummod 100,fold
R6701 T10157 T10155 appos fold,10
R6702 T10158 T10159 amod reduced,ratio
R6703 T10159 T10157 dobj ratio,fold
R6704 T10160 T10157 prep at,fold
R6705 T10161 T10162 nummod 18,h
R6706 T10162 T10160 pobj h,at
R6707 T10163 T10162 cc and,h
R6708 T10164 T10165 nummod 24,h
R6709 T10165 T10162 conj h,h
R6710 T10166 T10165 prep of,h
R6711 T10167 T10166 pobj incubation,of
R6712 T10168 T10165 punct ",",h
R6713 T10169 T10172 advmod i.e.,production
R6714 T10170 T10172 det a,production
R6715 T10171 T10172 amod higher,production
R6716 T10172 T10155 appos production,10
R6717 T10173 T10172 prep of,production
R6718 T10174 T10173 pobj IL-1RA,of
R6719 T10175 T10172 prep than,production
R6720 T10176 T10175 prep of,than
R6721 T10177 T10176 pobj IL-1β,of
R6722 T10178 T10181 punct (,3
R6723 T10179 T10181 advmod n,3
R6724 T10180 T10181 punct =,3
R6725 T10181 T10177 nummod 3,IL-1β
R6726 T10182 T10184 punct ;,p
R6727 T10183 T10184 nsubj both,p
R6728 T10184 T10188 ccomp p,Fig.
R6729 T10185 T10186 compound <,0.05
R6730 T10186 T10184 nummod 0.05,p
R6731 T10187 T10188 punct ;,Fig.
R6732 T10188 T10188 ROOT Fig.,Fig.
R6733 T10189 T10188 nummod 6,Fig.
R6734 T10190 T10188 punct ),Fig.
R6735 T10191 T10188 punct .,Fig.
R6736 T10192 T10194 det A,relevance
R6737 T10193 T10194 amod biological,relevance
R6738 T10194 T10199 nsubjpass relevance,suggested
R6739 T10195 T10194 prep of,relevance
R6740 T10196 T10197 det this,result
R6741 T10197 T10195 pobj result,of
R6742 T10198 T10199 auxpass was,suggested
R6743 T10199 T10199 ROOT suggested,suggested
R6744 T10200 T10199 agent by,suggested
R6745 T10201 T10202 det a,decrease
R6746 T10202 T10200 pobj decrease,by
R6747 T10203 T10202 prep of,decrease
R6748 T10204 T10207 det the,release
R6749 T10205 T10207 amod IL-1,release
R6750 T10206 T10207 amod dependent,release
R6751 T10207 T10203 pobj release,of
R6752 T10208 T10207 prep of,release
R6753 T10209 T10208 pobj IL-2,of
R6754 T10210 T10207 prep from,release
R6755 T10211 T10213 amod murine,cells
R6756 T10212 T10213 compound EL-4,cells
R6757 T10213 T10210 pobj cells,from
R6758 T10214 T10213 acl following,cells
R6759 T10215 T10217 compound GP,TSST-1
R6760 T10216 T10217 compound +,TSST-1
R6761 T10217 T10214 dobj TSST-1,following
R6762 T10218 T10219 advmod when,compared
R6763 T10219 T10199 advcl compared,suggested
R6764 T10220 T10219 prep to,compared
R6765 T10221 T10220 pobj TSST-1,to
R6766 T10222 T10221 cc or,TSST-1
R6767 T10223 T10225 dep GP/TSST,calc
R6768 T10224 T10225 nummod -1,calc
R6769 T10225 T10221 conj calc,TSST-1
R6770 T10226 T10199 punct .,suggested
R6771 T10227 T10238 punct (,p
R6772 T10228 T10238 dep data,p
R6773 T10229 T10230 neg not,shown
R6774 T10230 T10228 acl shown,data
R6775 T10231 T10230 prep in,shown
R6776 T10232 T10231 pobj detail,in
R6777 T10233 T10238 punct ",",p
R6778 T10234 T10238 advcl n,p
R6779 T10235 T10236 punct =,4
R6780 T10236 T10234 nummod 4,n
R6781 T10237 T10238 punct ;,p
R6782 T10238 T10238 ROOT p,p
R6783 T10239 T10240 compound <,0.07
R6784 T10240 T10238 dobj 0.07,p
R6785 T10241 T10238 punct ),p
R6786 T10242 T10238 punct .,p
R7143 T10891 T10895 nsubj Inhibition,led
R7144 T10892 T10891 prep of,Inhibition
R7145 T10893 T10894 compound transcription,factors
R7146 T10894 T10892 pobj factors,of
R7147 T10895 T10895 ROOT led,led
R7148 T10896 T10895 prep to,led
R7149 T10897 T10899 amod reduced,levels
R7150 T10898 T10899 compound IL-1RA,levels
R7151 T10899 T10896 pobj levels,to
R7152 T10900 T10901 amod Pharmacological,inhibitors
R7153 T10901 T10903 nsubjpass inhibitors,used
R7154 T10902 T10903 auxpass were,used
R7155 T10903 T10895 conj used,led
R7156 T10904 T10905 aux to,demonstrate
R7157 T10905 T10903 xcomp demonstrate,used
R7158 T10906 T10915 mark that,are
R7159 T10907 T10910 det the,sites
R7160 T10908 T10909 compound transcription,factor
R7161 T10909 T10910 compound factor,sites
R7162 T10910 T10915 nsubj sites,are
R7163 T10911 T10910 prep within,sites
R7164 T10912 T10914 det the,promoter
R7165 T10913 T10914 compound IL-1RA,promoter
R7166 T10914 T10911 pobj promoter,within
R7167 T10915 T10905 ccomp are,demonstrate
R7168 T10916 T10915 acomp relevant,are
R7169 T10917 T10916 prep for,relevant
R7170 T10918 T10919 det the,induction
R7171 T10919 T10917 pobj induction,for
R7172 T10920 T10919 prep of,induction
R7173 T10921 T10920 pobj IL-1RA,of
R7174 T10922 T10919 prep by,induction
R7175 T10923 T10922 pobj GP,by
R7176 T10924 T10903 punct .,used
R7177 T10925 T10926 mark As,expected
R7178 T10926 T10953 advcl expected,overruled
R7179 T10927 T10953 punct ",",overruled
R7180 T10928 T10929 det an,inhibition
R7181 T10929 T10953 nsubjpass inhibition,overruled
R7182 T10930 T10929 prep of,inhibition
R7183 T10931 T10930 pobj NFκB,of
R7184 T10932 T10929 prep via,inhibition
R7185 T10933 T10934 compound CAPE,[
R7186 T10934 T10932 pobj [,via
R7187 T10935 T10936 nummod 35,]
R7188 T10936 T10934 conj ],[
R7189 T10937 T10936 cc and,]
R7190 T10938 T10936 conj CyA,]
R7191 T10939 T10938 punct ",",CyA
R7192 T10940 T10938 conj NFAT,CyA
R7193 T10941 T10934 prep via,[
R7194 T10942 T10941 pobj CyA,via
R7195 T10943 T10942 cc and,CyA
R7196 T10944 T10942 conj NFIL-6,CyA
R7197 T10945 T10929 prep via,inhibition
R7198 T10946 T10947 compound CHX,[
R7199 T10947 T10945 pobj [,via
R7200 T10948 T10949 nummod 36,]
R7201 T10949 T10953 nsubjpass ],overruled
R7202 T10950 T10953 aux could,overruled
R7203 T10951 T10953 neg not,overruled
R7204 T10952 T10953 auxpass be,overruled
R7205 T10953 T10953 ROOT overruled,overruled
R7206 T10954 T10953 agent by,overruled
R7207 T10955 T10954 pobj GP,by
R7208 T10956 T10953 punct ",",overruled
R7209 T10957 T10953 advcl leading,overruled
R7210 T10958 T10957 prep to,leading
R7211 T10959 T10962 det a,activity
R7212 T10960 T10962 amod down-regulated,activity
R7213 T10961 T10962 amod binding,activity
R7214 T10962 T10958 pobj activity,to
R7215 T10963 T10962 prep of,activity
R7216 T10964 T10966 det the,factors
R7217 T10965 T10966 compound transcription,factors
R7218 T10966 T10963 pobj factors,of
R7219 T10967 T10962 prep to,activity
R7220 T10968 T10970 det the,sites
R7221 T10969 T10970 compound IL-1RA,sites
R7222 T10970 T10967 pobj sites,to
R7223 T10971 T10957 punct ",",leading
R7224 T10972 T10953 cc and,overruled
R7225 T10973 T10974 det a,reduction
R7226 T10974 T10953 conj reduction,overruled
R7227 T10975 T10974 prep of,reduction
R7228 T10976 T10977 compound IL-1RA,mRNA
R7229 T10977 T10981 nmod mRNA,levels
R7230 T10978 T10977 cc and,mRNA
R7231 T10979 T10977 conj IL-1RA,mRNA
R7232 T10980 T10981 compound protein,levels
R7233 T10981 T10975 pobj levels,of
R7234 T10982 T10981 punct (,levels
R7235 T10983 T10981 appos Fig.,levels
R7236 T10984 T10983 nummod 7,Fig.
R7237 T10985 T10983 punct ),Fig.
R7238 T10986 T10953 punct .,overruled
R7239 T10987 T10988 det The,extent
R7240 T10988 T10996 nsubjpass extent,shown
R7241 T10989 T10988 prep of,extent
R7242 T10990 T10989 pobj reduction,of
R7243 T10991 T10990 prep in,reduction
R7244 T10992 T10991 pobj NFATP2/3,in
R7245 T10993 T10992 advmod binding,NFATP2/3
R7246 T10994 T10996 auxpass is,shown
R7247 T10995 T10996 advmod exemplarily,shown
R7248 T10996 T10996 ROOT shown,shown
R7249 T10997 T10996 prep in,shown
R7250 T10998 T10999 det an,autoradiogram
R7251 T10999 T10997 pobj autoradiogram,in
R7252 T11000 T11002 punct (,7A
R7253 T11001 T11002 compound Fig.,7A
R7254 T11002 T10999 appos 7A,autoradiogram
R7255 T11003 T11002 punct ",",7A
R7256 T11004 T11002 acl left,7A
R7257 T11005 T11004 npadvmod side,left
R7258 T11006 T11002 punct ),7A
R7259 T11007 T10996 cc and,shown
R7260 T11008 T11009 advmod graphically,summarized
R7261 T11009 T10996 conj summarized,shown
R7262 T11010 T11009 punct (,summarized
R7263 T11011 T11013 advmod n,4
R7264 T11012 T11013 punct =,4
R7265 T11013 T11009 dobj 4,summarized
R7266 T11014 T11009 punct ",",summarized
R7267 T11015 T11016 compound Fig.,7A
R7268 T11016 T11016 ROOT 7A,7A
R7269 T11017 T11019 punct ",",side
R7270 T11018 T11019 amod right,side
R7271 T11019 T11016 appos side,7A
R7272 T11020 T11016 punct ),7A
R7273 T11021 T10996 punct .,shown
R7274 T11022 T11023 det The,results
R7275 T11023 T11031 nsubj results,were
R7276 T11024 T11023 prep for,results
R7277 T11025 T11026 det the,NFκB
R12062 T17771 T17778 nsubjpass Isolation,obtained
R12063 T17772 T17771 prep of,Isolation
R12064 T17773 T17776 amod human,coats
R12065 T17774 T17775 compound PBMC,Buffy
R12066 T17775 T17776 compound Buffy,coats
R12067 T17776 T17772 pobj coats,of
R12068 T17777 T17778 auxpass were,obtained
R12069 T17778 T17778 ROOT obtained,obtained
R12070 T17779 T17778 prep from,obtained
R12071 T17780 T17782 amod healthy,donors
R12072 T17781 T17782 compound blood,donors
R12073 T17782 T17779 pobj donors,from
R12074 T17783 T17778 prep in,obtained
R12075 T17784 T17783 pobj compliance,in
R12076 T17785 T17784 prep with,compliance
R12077 T17786 T17788 det the,declaration
R12078 T17787 T17788 compound Helsinki,declaration
R12079 T17788 T17785 pobj declaration,with
R12080 T17789 T17785 cc and,with
R12081 T17790 T17785 conj with,with
R12082 T17791 T17792 det the,approval
R12083 T17792 T17790 pobj approval,with
R12084 T17793 T17792 prep of,approval
R12085 T17794 T17796 det the,committee
R12109 T17818 T17821 compound gradient,]
R12110 T17819 T17821 compound [,]
R12111 T17820 T17821 compound "54,55",]
R12112 T17821 T17807 npadvmod ],separated
R12113 T17822 T17807 punct .,separated
R12114 T17823 T17828 prep Following,cultured
R12115 T17824 T17823 pobj isolation,Following
R12116 T17825 T17828 punct ",",cultured
R12117 T17826 T17828 nsubjpass PBMC,cultured
R12118 T17827 T17828 auxpass were,cultured
R12119 T17828 T17828 ROOT cultured,cultured
R12120 T17829 T17828 prep at,cultured
R12121 T17830 T17832 det a,concentration
R12122 T17831 T17832 amod final,concentration
R12123 T17832 T17829 pobj concentration,at
R12124 T17833 T17832 prep of,concentration
R12125 T17834 T17837 nummod 3,cells/ml
R12126 T17835 T17837 nummod ×,cells/ml
R12127 T17836 T17837 nummod 106,cells/ml
R12128 T17837 T17833 pobj cells/ml,of
R12129 T17838 T17837 punct (,cells/ml
R12130 T17839 T17837 prep for,cells/ml
R12131 T17840 T17841 compound ELISA,measurements
R12132 T17841 T17839 pobj measurements,for
R12133 T17842 T17837 punct ),cells/ml
R12134 T17843 T17832 cc or,concentration
R12135 T17844 T17845 nummod 5,×
R12136 T17845 T17876 nmod ×,containing
R12137 T17846 T17845 nummod 106/ml,×
R12138 T17847 T17848 punct (,for
R12139 T17848 T17845 prep for,×
R12140 T17849 T17850 compound gel,shifts
R12141 T17850 T17848 pobj shifts,for
R12142 T17851 T17848 punct ),for
R12143 T17852 T17845 cc or,×
R12144 T17853 T17856 nummod 1,cells/ml
R12152 T17861 T17858 punct ),for
R12153 T17862 T17856 prep in,cells/ml
R12154 T17863 T17865 nmod RPMI,medium
R12155 T17864 T17865 nummod 1640,medium
R12156 T17865 T17862 pobj medium,in
R12157 T17866 T17876 punct (,containing
R12158 T17867 T17876 dep BioWhittaker,containing
R12159 T17868 T17867 punct ",",BioWhittaker
R12160 T17869 T17867 conj Heidelberg,BioWhittaker
R12161 T17870 T17869 punct ",",Heidelberg
R12162 T17871 T17867 npadvmod Germany,BioWhittaker
R12163 T17872 T17867 punct ",",BioWhittaker
R12164 T17873 T17867 appos LPS-free,BioWhittaker
R12165 T17874 T17873 punct ),LPS-free
R12166 T17875 T17876 punct ",",containing
R12167 T17876 T17828 advcl containing,cultured
R12168 T17877 T17878 nummod 10,%
R12169 T17878 T17882 nmod %,serum
R12170 T17879 T17882 amod heat-inactivated,serum
R12171 T17880 T17881 amod fetal,calf
R12172 T17881 T17882 compound calf,serum
R12173 T17882 T17876 dobj serum,containing
R12174 T17883 T17905 punct (,streptomycin
R12175 T17884 T17905 nmod FCS,streptomycin
R12176 T17885 T17884 punct ",",FCS
R12177 T17886 T17884 conj low-LPS,FCS
R12178 T17887 T17886 punct ",",low-LPS
R12179 T17888 T17886 conj Invitrogen,low-LPS
R12180 T17889 T17888 punct ",",Invitrogen
R12181 T17890 T17888 conj Karlsruhe,Invitrogen
R10981 T16133 T16132 punct (,cells
R13276 T19395 T19401 nsubj Immuno,determine
R13703 T20004 T20005 amod Cytokine,measurements
R4953 T7394 T7395 compound GP/LPS,calc
R4955 T7395 T7392 appos calc,LPS
R4956 T7396 T7375 punct .,were
R4957 T7397 T7375 cc and,were
R4958 T7398 T7400 compound GP,TSST-1
R4959 T7399 T7400 compound +,TSST-1
R4960 T7400 T7375 attr TSST-1,were
R4961 T7401 T7400 cc or,TSST-1
R4963 T7402 T7400 conj GP/TSST,TSST-1
R4964 T7403 T7404 nummod -1,calc
R4965 T7404 T7400 npadvmod calc,TSST-1
R4966 T7405 T7375 punct .,were
R4967 T7406 T7407 quantmod over,48
R4968 T7407 T7408 nummod 48,h
R4970 T7408 T7412 npadvmod h,shown
R4971 T7409 T7412 punct (,shown
R4972 T7410 T7412 nsubjpass data,shown
R4973 T7411 T7412 neg not,shown
R4974 T7412 T7412 ROOT shown,shown
R4975 T7413 T7412 punct ),shown
R4977 T7414 T7412 punct .,shown
R1118 T2109 T2111 amod β-1,3-D-glucans
R1119 T2110 T2111 compound →,3-D-glucans
R1120 T2111 T2112 nsubj 3-D-glucans,occur
R1121 T2112 T2112 ROOT occur,occur
R1122 T2113 T2112 prep as,occur
R1123 T2114 T2116 det a,component
R1124 T2115 T2116 amod principal,component
R1125 T2116 T2113 pobj component,as
R1126 T2117 T2116 prep of,component
R1127 T2118 T2120 amod microbial,walls
R1128 T2119 T2120 compound cell,walls
R1129 T2120 T2117 pobj walls,of
R1135 T2121 T2112 cc or,occur
R1140 T2122 T2124 aux can,secreted
R1144 T2123 T2124 auxpass be,secreted
R1148 T2124 T2112 conj secreted,occur
R1152 T2125 T2124 prep from,secreted
R1156 T2126 T2128 preconj both,non-pathogenic
R1161 T2127 T2126 punct ",",both
R11855 T17554 T17547 punct .,prepared
R11856 T17555 T17557 det The,characteristics
R11857 T17556 T17557 amod physicochemical,characteristics
R11858 T17557 T17561 nsubjpass characteristics,determined
R11859 T17558 T17557 prep of,characteristics
R11860 T17559 T17558 pobj GP,of
R11861 T17560 T17561 auxpass were,determined
R11862 T17561 T17561 ROOT determined,determined
R11863 T17562 T17563 mark as,reported
R11864 T17563 T17561 advcl reported,determined
R11865 T17564 T17567 advmod previously,]
R11866 T17565 T17567 compound [,]
R11867 T17566 T17567 compound "20,26",]
R11868 T17567 T17563 nsubj ],reported
R11869 T17568 T17561 punct .,determined
R11870 T17569 T17571 nsubjpass GP,dissolved
R11871 T17570 T17571 auxpass was,dissolved
R11872 T17571 T17571 ROOT dissolved,dissolved
R11873 T17572 T17571 prep in,dissolved
R11874 T17573 T17574 amod aqueous,media
R11875 T17574 T17572 pobj media,in

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T24886 21450-21460 Gene_expression denotes production
T24885 21479-21484 Protein denotes IL-1β
T24884 21464-21470 Protein denotes IL-1RA
T26190 27870-27885 Protein denotes IL-1RA promoter
T25573 23549-23556 Negative_regulation denotes reduced
T25572 23549-23556 Negative_regulation denotes reduced
T25571 23561-23571 Gene_expression denotes production
T25570 23499-23509 Negative_regulation denotes Inhibition
T25569 23575-23581 Protein denotes IL-1RA
T25568 23528-23534 Protein denotes NFIL-6
T25567 23519-23523 Protein denotes NFAT
T25566 23513-23517 Protein denotes NFκB
T25565 23429-23434 Protein denotes GAPDH
T25564 23364-23373 Negative_regulation denotes decreased
T25560 23345-23351 Protein denotes NFIL-6
T25559 23336-23340 Protein denotes NFAT
T25558 23330-23334 Protein denotes NFκB
T25557 23158-23171 Protein denotes NFATP2/3 site
T25556 22867-22874 Binding denotes binding
T25555 22867-22874 Binding denotes binding
T25554 22867-22874 Binding denotes binding
T25553 22816-22826 Negative_regulation denotes Inhibition
T25552 22816-22826 Negative_regulation denotes Inhibition
T25551 22882-22897 Protein denotes IL-1RA promoter
T25550 22856-22862 Protein denotes NFIL-6
T25549 22847-22851 Protein denotes NFAT
T25548 22841-22845 Protein denotes NFκB
T24887 21450-21460 Gene_expression denotes production
T24883 21292-21306 Protein denotes vs GP + TSST-1
T24882 21276-21290 Protein denotes GP/TSST-1 calc
T24881 21266-21272 Protein denotes TSST-1
T24880 21201-21212 Regulation denotes alterations
T24879 21201-21212 Regulation denotes alterations
T24878 21226-21232 Protein denotes IL-1RA
T24877 21220-21225 Protein denotes IL-1β
T24876 21080-21090 Positive_regulation denotes generating
T24875 21080-21090 Positive_regulation denotes generating
T24874 21107-21113 Protein denotes IL-1RA
T24873 21096-21101 Protein denotes IL-1β
T24872 20913-20925 Protein denotes IL-1β/IL-1RA
T24871 20811-20820 Negative_regulation denotes Decreased
T24870 20879-20885 Protein denotes TSST-1
T24869 20821-20833 Protein denotes IL-1β/IL-1RA
T24243 19246-19254 Positive_regulation denotes elevated
T24242 19264-19271 Binding denotes binding
T24241 19300-19315 Protein denotes IL-1RA promoter
T24240 19255-19263 Protein denotes NFAT-DNA
T24239 18953-18968 Protein denotes IL-1RA promoter
T22439 10700-10708 Gene_expression denotes positive
T22438 10700-10708 Gene_expression denotes positive
T22437 10700-10708 Gene_expression denotes positive
T22436 10700-10708 Gene_expression denotes positive
T22435 10581-10589 Gene_expression denotes positive
T22434 10581-10589 Gene_expression denotes positive
T22433 10581-10589 Gene_expression denotes positive
T22432 10740-10742 Protein denotes c1
T22431 10731-10738 Protein denotes NFAT c2
T22430 10723-10726 Protein denotes p50
T22429 10713-10721 Protein denotes NFκB p65
T22428 10624-10626 Protein denotes c2
T22427 10612-10622 Protein denotes for NFATc1
T22426 10604-10607 Protein denotes p65
T22425 10594-10602 Protein denotes NFκB p50
T22424 10529-10534 Protein denotes c-rel
T22423 10524-10527 Protein denotes p52
T22422 10498-10523 Protein denotes recombinant proteins NFκB
T22421 10379-10383 Protein denotes NFAT
T22420 10370-10374 Protein denotes NFκB
T22419 10274-10281 Binding denotes binding
T22418 10274-10281 Binding denotes binding
T22417 10274-10281 Binding denotes binding
T22416 10274-10281 Binding denotes binding
T22415 10274-10281 Binding denotes binding
T22414 10274-10281 Binding denotes binding
T22413 10239-10241 Protein denotes c1
T22412 10232-10238 Protein denotes NFATc2
T22411 10224-10227 Protein denotes p50
T22410 10220-10223 Protein denotes p65
T22409 10215-10219 Protein denotes NFκB
T21552 9890-9898 Protein denotes NFκB-DNA
T21551 9610-9617 Binding denotes binding
T18512 35501-35508 Positive_regulation denotes crucial
T18511 35501-35508 Positive_regulation denotes crucial
T18510 35517-35524 Binding denotes binding
T18509 35517-35524 Binding denotes binding
T18508 35364-35372 Entity denotes promoter
T18507 35537-35550 Protein denotes NFκB proteins
T18506 35528-35532 Protein denotes NFAT
T18505 35417-35430 Protein denotes TNFα promoter
T18504 35389-35409 Protein denotes κ consensus sequence
T18503 35359-35363 Protein denotes IFNγ
T18502 35344-35351 Protein denotes P2 site
T18501 35140-35143 Protein denotes PNK
T18500 35135-35138 Protein denotes Kit
T18499 34874-34903 Protein denotes IL-8, IFNγ and IL-6 promoters
T18498 34868-34872 Protein denotes TNFα
T17280 32860-32866 Protein denotes glucan
T17279 32693-32702 Regulation denotes regulated
T17278 32693-32702 Regulation denotes regulated
T17277 32595-32602 Binding denotes binding
T17276 32595-32602 Binding denotes binding
T17275 32671-32674 Protein denotes Fig
T17274 32654-32669 Protein denotes IL-1RA promoter
T17273 32377-32383 Protein denotes TSST-1
T12514 31996-32009 Protein denotes peptidoglycan
T12513 31988-31991 Protein denotes LPS
T12512 31983-31986 Protein denotes PRR
T12511 31720-31730 Positive_regulation denotes Activation
T12510 31847-31851 Protein denotes PI3K
T12509 31843-31845 Protein denotes GP
T12508 31734-31738 Protein denotes NFκB
T12507 31684-31694 Positive_regulation denotes activation
T12506 31698-31702 Protein denotes NFAT
T12491 30805-30810 Protein denotes IL-1β
T12490 30793-30799 Protein denotes IL-1RA
T12489 30652-30660 Negative_regulation denotes decrease
T12488 30668-30680 Protein denotes IL-1β/IL-1RA
T12487 30352-30360 Positive_regulation denotes increase
T12486 30379-30386 Binding denotes binding
T12485 30474-30487 Protein denotes NFATP2/3 site
T12484 30433-30449 Protein denotes NFIL-6 site [32]
T12483 30408-30412 Protein denotes NFκB
T12482 30398-30403 Protein denotes NFκB3
T12481 30039-30051 Protein denotes NFκB2/3 site
T12480 29948-29963 Protein denotes IL-1RA promoter
T12479 29863-29867 Protein denotes NFκB
T12478 29753-29763 Protein denotes TNFα motif
T12477 29678-29690 Protein denotes IL-1RA motif
T12476 29668-29673 Protein denotes NFκB3
T12475 29647-29662 Protein denotes IL-1RA promoter
T12474 29634-29638 Protein denotes TNFα
T12473 29603-29607 Protein denotes NFκB
T12472 29528-29541 Protein denotes NFκB subunits
T12471 29312-29319 Positive_regulation denotes induced
T12470 29312-29319 Positive_regulation denotes induced
T12469 29269-29284 Negative_regulation denotes down-regulation
T12468 29269-29284 Negative_regulation denotes down-regulation
T12467 29377-29390 Positive_regulation denotes up-regulation
T12466 29377-29390 Positive_regulation denotes up-regulation
T12465 29377-29390 Positive_regulation denotes up-regulation
T12464 29325-29332 Binding denotes binding
T12463 29325-29332 Binding denotes binding
T12462 29432-29447 Protein denotes IL-1RA promoter
T12461 29404-29408 Protein denotes NFκB
T12460 29394-29399 Protein denotes NFκB3
T12459 29349-29362 Protein denotes TNFα promoter
T12458 29320-29324 Protein denotes NFκB
T12457 29305-29311 Protein denotes TSST-1
T12456 29216-29225 Positive_regulation denotes increased
T12455 29120-29127 Binding denotes binding
T12454 29183-29187 Protein denotes NFκB
T12453 29135-29140 Protein denotes NFκB3
T12452 29068-29083 Protein denotes IL-1RA promoter
T12451 29048-29058 Protein denotes NFκB sites
T12450 28835-28842 Binding denotes binding
T12449 28835-28842 Binding denotes binding
T12441 28713-28717 Protein denotes IL-8
T12440 28660-28664 Protein denotes NFAT
T12439 28649-28655 Protein denotes NFIL-6
T12438 28643-28647 Protein denotes NFκB
T12437 28617-28623 Protein denotes TSST-1
T12436 28353-28360 Regulation denotes altered
T12435 28353-28360 Regulation denotes altered
T12434 28523-28536 Positive_regulation denotes up-regulation
T12433 28447-28462 Negative_regulation denotes down-regulation
T12432 28447-28462 Negative_regulation denotes down-regulation
T12431 28540-28546 Protein denotes IL-1RA
T12430 28476-28480 Protein denotes IL-6
T12429 28466-28471 Protein denotes IL-1β
T12428 28386-28392 Protein denotes IL-1RA
T12427 28380-28385 Protein denotes IL-1β
T12426 27612-27621 Positive_regulation denotes induction
T12425 27651-27655 Protein denotes IL-8
T12424 27570-27576 Negative_regulation denotes kinase
T12423 27570-27576 Negative_regulation denotes kinase
T12422 27570-27576 Negative_regulation denotes kinase
T12421 27570-27576 Negative_regulation denotes kinase
T12420 27408-27415 Binding denotes binding
T12419 27548-27551 Protein denotes p38
T12418 27539-27543 Protein denotes PI3K
T12417 27512-27516 Protein denotes TNFα
T12416 27457-27507 Protein denotes T cell receptor, leading to release of mainly IFNγ
T12415 27419-27435 Protein denotes MHC-II molecules
T12414 27388-27394 Protein denotes TSST-1
T12413 27358-27382 Protein denotes A bacterial superantigen
T12412 27301-27311 Gene_expression denotes expression
T12300 26925-26932 Gene_expression denotes produce
T12299 26946-26952 Protein denotes IL-1RA
T12298 26933-26937 Protein denotes IL-8
T12297 26695-26704 Positive_regulation denotes induction
T12296 26695-26704 Positive_regulation denotes induction
T12295 26455-26463 Negative_regulation denotes decrease
T12294 26455-26463 Negative_regulation denotes decrease
T12293 26455-26463 Negative_regulation denotes decrease
T12292 26716-26719 Protein denotes Fig
T12291 26708-26714 Protein denotes IL-1RA
T12290 26543-26554 Protein denotes IL-1RA mRNA
T12289 26513-26528 Protein denotes IL-1RA promoter
T12288 26482-26488 Protein denotes NFIL-6
T12287 26473-26477 Protein denotes NFAT
T12286 26467-26471 Protein denotes NFκB
T12285 26228-26237 Positive_regulation denotes induction
T12284 26228-26237 Positive_regulation denotes induction
T12283 26184-26189 Positive_regulation denotes leads
T12282 26289-26292 Regulation denotes due
T12281 26265-26272 Binding denotes binding
T12280 26265-26272 Binding denotes binding
T12279 26228-26237 Positive_regulation denotes induction
T12278 26193-26203 Gene_expression denotes production
T12277 26421-26436 Protein denotes IL-1RA promoter
T12276 26406-26416 Protein denotes IFNγ, IL-6
T12505 31639-31643 Protein denotes PI3K
T12504 31577-31585 Regulation denotes controls
T12503 31577-31585 Regulation denotes controls
T12502 31608-31618 Gene_expression denotes production
T12501 31608-31618 Gene_expression denotes production
T12500 31602-31607 Protein denotes IL-1β
T12499 31586-31593 Protein denotes sIL-1RA
T12498 31552-31556 Protein denotes PI3K
T12497 31395-31399 Protein denotes PI3K
T12496 31362-31368 Protein denotes TSST-1
T12495 31080-31084 Protein denotes IL-1
T12494 31014-31025 Negative_regulation denotes inactivated
T12493 30993-30998 Protein denotes IL-1β
T12492 30885-30897 Protein denotes IL-1β/IL-1RA
T11943 24301-24305 Protein denotes NFAT
T11942 24289-24295 Protein denotes NFIL-6
T11941 24282-24286 Protein denotes NFκB
T11940 23900-23904 Protein denotes PI3K
T11939 23891-23895 Protein denotes NFκB
T12275 26388-26392 Protein denotes NFAT
T12274 26355-26386 Protein denotes activated transcription factors
T12273 26254-26264 Protein denotes NFIL-6 DNA
T12272 26241-26249 Protein denotes NFATP2/3
T12271 26207-26213 Protein denotes IL-1RA
T12270 26181-26183 Protein denotes GP
T12269 25939-25942 Entity denotes [34
T12268 26079-26091 Protein denotes NFκB2/3 site
T12267 26034-26038 Protein denotes NFκB
T12266 25995-26000 Protein denotes NFκB3
T12265 25923-25938 Protein denotes IL-1RA promoter
T12264 25834-25841 Positive_regulation denotes induced
T12263 25804-25810 Positive_regulation denotes induce
T12262 25842-25848 Protein denotes IL-1RA
T12261 25811-25816 Protein denotes IL-1β
T12260 25598-25608 Positive_regulation denotes supporting
T12259 25621-25631 Regulation denotes regulating
T12258 25637-25644 Binding denotes binding
T12257 25739-25747 Protein denotes κB motif
T12256 25632-25636 Protein denotes NFκB
T12255 25583-25588 Protein denotes IL-1β
T12254 25574-25578 Protein denotes TNFα
T12253 25547-25559 Protein denotes κB half site
T10855 22780-22789 Negative_regulation denotes decreased
T8731 18109-18117 Positive_regulation denotes increase
T8730 18121-18128 Binding denotes binding
T8729 17991-17999 Protein denotes NFATP2/3
T8728 17850-17859 Positive_regulation denotes increased
T8727 17860-17867 Binding denotes binding
T8726 17875-17886 Protein denotes NFIL-6 site
T8725 17705-17718 Positive_regulation denotes up-regulation
T8724 17722-17729 Binding denotes binding
T8723 17644-17655 Protein denotes NFIL-6 site
T8722 17405-17413 Positive_regulation denotes elevated
T8721 17328-17335 Binding denotes Binding
T8720 17345-17347 Protein denotes κB
T8719 16981-16988 Binding denotes binding
T8718 17096-17102 Protein denotes TSST-1
T8717 17000-17006 Protein denotes TSST-1
T8716 16715-16732 Protein denotes LPS responsive κB
T8715 16482-16486 Binding denotes bind
T8714 16503-16518 Protein denotes IL-1RA promoter
T8713 16405-16417 Protein denotes IL-6 or IFNγ
T8712 16399-16403 Protein denotes TNFα
T8711 16380-16390 Protein denotes NFAT sites
T8710 16369-16375 Protein denotes NFIL-6
T8709 16363-16367 Protein denotes NFκB
T8708 16282-16296 Positive_regulation denotes TSST-1-induced
T8707 16202-16206 Positive_regulation denotes Role
T8706 16202-16206 Positive_regulation denotes Role
T8705 16304-16314 Gene_expression denotes expression
T8704 16232-16239 Binding denotes binding
T8703 16232-16239 Binding denotes binding
T8702 16297-16303 Protein denotes IL-1RA
T8701 16227-16231 Protein denotes NFAT
T8700 16216-16222 Protein denotes NFIL-6
T8699 16210-16214 Protein denotes NFκB
T6303 16016-16023 Positive_regulation denotes induced
T6302 16016-16023 Positive_regulation denotes induced
T6301 16016-16023 Positive_regulation denotes induced
T6300 16016-16023 Positive_regulation denotes induced
T6299 15958-15968 Gene_expression denotes production
T6298 15958-15968 Gene_expression denotes production
T6297 15958-15968 Gene_expression denotes production
T6296 15958-15968 Gene_expression denotes production
T6295 16001-16007 Protein denotes TGFβ 1
T6294 15991-15996 Protein denotes IL-10
T6293 15978-15989 Protein denotes IL-12, IL-4
T6292 15972-15976 Protein denotes IL-2
T6291 15948-15953 Protein denotes TGFβ1
T6290 15941-15946 Protein denotes IL-10
T6289 15928-15939 Protein denotes IL-12, IL-4
T6288 15922-15926 Protein denotes IL-2
T6268 15035-15039 Protein denotes IL-8
T6267 14924-14930 Protein denotes IL-1RA
T6266 14915-14919 Protein denotes IL-8
T6265 14794-14804 Positive_regulation denotes GP-induced
T6264 14794-14804 Positive_regulation denotes GP-induced
T6263 14821-14832 Gene_expression denotes productions
T6262 14821-14832 Gene_expression denotes productions
T6260 14805-14809 Protein denotes IL-8
T6259 14687-14695 Positive_regulation denotes elevated
T6258 14725-14731 Protein denotes IL-1RA
T6257 14473-14481 Positive_regulation denotes increase
T6256 14492-14502 Gene_expression denotes production
T6255 14539-14545 Protein denotes TSST-1
T6254 14485-14491 Protein denotes IL-1RA
T6253 14368-14373 Regulation denotes alter
T6252 14407-14417 Gene_expression denotes production
T6251 14400-14406 Protein denotes IL-1RA
T6250 14203-14211 Gene_expression denotes produced
T6249 14203-14211 Gene_expression denotes produced
T6248 14164-14170 Protein denotes IL-1RA
T6247 14158-14162 Protein denotes IL-8
T6246 14093-14107 Protein denotes GP/TSST-1 calc
T6245 14083-14089 Protein denotes TSST-1
T6244 13554-13563 Negative_regulation denotes decreased
T6243 13569-13579 Gene_expression denotes production
T6242 13613-13619 Protein denotes TSST-1
T6241 13564-13568 Protein denotes IL-6
T6240 13470-13480 Regulation denotes alteration
T6239 13488-13499 Positive_regulation denotes LPS-induced
T6238 13505-13515 Gene_expression denotes production
T6237 13405-13412 Positive_regulation denotes induced
T6236 13500-13504 Protein denotes IL-6
T6235 13436-13440 Protein denotes IL-6
T6234 12104-12113 Negative_regulation denotes reduction
T6233 12146-12151 Protein denotes IL-1β
T6232 11919-11928 Negative_regulation denotes reduction
T6231 12001-12007 Protein denotes TSST-1
T6230 11932-11937 Protein denotes IL-1β
T6229 11796-11809 Positive_regulation denotes up-regulation
T6228 11819-11829 Gene_expression denotes production
T6227 11813-11818 Protein denotes IL-1β
T6226 11710-11720 Gene_expression denotes production
T6225 11704-11709 Protein denotes IL-1β
T6224 11063-11073 Gene_expression denotes production
T6223 11063-11073 Gene_expression denotes production
T6222 11063-11073 Gene_expression denotes production
T6221 11063-11073 Gene_expression denotes production
T6220 11095-11099 Protein denotes IFNγ
T6219 11089-11093 Protein denotes IL-6
T6218 11083-11087 Protein denotes IL-8
T6217 11077-11081 Protein denotes TNFα
T6216 10981-10995 Protein denotes IFNγ promoters
T6215 10972-10976 Protein denotes IL-6
T6214 10960-10970 Protein denotes TNFα, IL-8
T3731 6564-6570 Negative_regulation denotes degree
T3732 6564-6570 Negative_regulation denotes degree
T3733 6564-6570 Negative_regulation denotes degree
T3734 6564-6570 Negative_regulation denotes degree
T3735 6564-6570 Negative_regulation denotes degree
T3736 6684-6692 Protein denotes NFκB p65
T3737 6718-6721 Protein denotes p50
T3738 6731-6734 Protein denotes p52
T3739 6673-6680 Binding denotes binding
T3740 6673-6680 Binding denotes binding
T3741 6739-6747 Gene_expression denotes negative
T3742 6831-6835 Protein denotes NFκB
T3743 6863-6876 Protein denotes TNFα promoter
T3744 6949-6953 Protein denotes NFκB
T3745 6836-6843 Binding denotes binding
T3746 6836-6843 Binding denotes binding
T3747 6954-6961 Binding denotes binding
T3748 6920-6929 Negative_regulation denotes decreased
T3749 7235-7239 Protein denotes NFAT
T3750 7261-7274 Protein denotes IFNγ promoter
T3751 7276-7283 Protein denotes Fig. 1A
T3752 7201-7208 Binding denotes binding
T3753 7308-7321 Protein denotes NFAT subunits
T3754 7359-7365 Protein denotes NFATc2
T3755 7392-7398 Protein denotes NFATc1
T3756 7400-7403 Protein denotes Fig
T3757 7348-7355 Binding denotes binding
T3758 7382-7388 Negative_regulation denotes degree
T3759 7382-7388 Negative_regulation denotes degree
T6261 14814-14820 Protein denotes IL-1RA
T11952 24659-24663 Protein denotes IL-8
T11953 24668-24674 Protein denotes IL-1RA
T11951 24388-24395 Binding denotes binding
T11950 24383-24387 Protein denotes NFAT
T11949 24263-24270 Positive_regulation denotes induced
T11948 24263-24270 Positive_regulation denotes induced
T11947 24263-24270 Positive_regulation denotes induced
T11946 24271-24278 Binding denotes binding
T11945 24271-24278 Binding denotes binding
T11944 24271-24278 Binding denotes binding
T12240 25145-25166 Protein denotes NFκB p65/65 homodimer
T12239 25095-25099 Protein denotes IL-8
T12238 24920-24927 Binding denotes binding
T12237 25000-25013 Protein denotes IL-8 promoter
T12236 24975-24977 Protein denotes κB
T12235 24966-24969 Protein denotes p50
T12234 24931-24939 Protein denotes NFκB p65
T12233 24676-24683 Protein denotes Fig. 3B
T12252 25499-25520 Protein denotes p65 binding half site
T12251 25451-25457 Protein denotes IL-8κB
T12250 25394-25401 Binding denotes binding
T12249 25394-25401 Binding denotes binding
T12248 25335-25349 Positive_regulation denotes transactivated
T12247 25409-25420 Protein denotes IL-8κB site
T12246 25381-25387 Protein denotes NFATc2
T12245 25363-25369 Protein denotes NFIL-6
T12244 25350-25358 Protein denotes NFκB p65
T12243 25082-25091 Positive_regulation denotes induction
T12242 25127-25137 Positive_regulation denotes activation
T12241 25100-25113 Transcription denotes transcription
T12304 27347-27356 Protein denotes TNFα [43]
T12303 27276-27280 Protein denotes NFκB
T12302 27222-27242 Protein denotes Toll-like receptor 4
T12301 26925-26932 Gene_expression denotes produce
T12516 32010-32019 Positive_regulation denotes activated
T12515 32024-32030 Protein denotes IL-1RA
T12448 28869-28882 Protein denotes TNFα promoter
T12447 28846-28850 Protein denotes NFκB
T12446 28774-28787 Protein denotes IFNγ promoter
T12445 28766-28770 Protein denotes IL-6
T12444 28759-28764 Protein denotes IL-1β
T12443 28753-28757 Protein denotes TNFα
T12442 28722-28737 Protein denotes IL-1RA promoter
T19230 37350-37353 Protein denotes IgG
T19229 37267-37296 Protein denotes goat polyclonal IgG1 antisera
T19228 37193-37197 Protein denotes N466
T19227 37181-37191 Protein denotes anti-c-rel
T19226 37154-37179 Protein denotes polyclonal IgG1 antiserum
T19225 37122-37126 Protein denotes NFκB
T19224 37096-37100 Protein denotes NFκB
T19223 37063-37076 Protein denotes anti-NFκB p50
T19222 36939-36947 Protein denotes NFκB p52
T19221 36686-36690 Protein denotes NFAT
T19220 36677-36681 Protein denotes NFκB
T12517 32010-32019 Positive_regulation denotes activated
T20315 39932-39946 Protein denotes IL-1RA protein
T20314 39890-39895 Protein denotes GAPDH
T20313 39811-39817 Protein denotes IL-1RA
T20312 39682-39699 Protein denotes GAPDH transcripts
T20311 39671-39677 Protein denotes IL-1RA
T20310 39614-39621 Protein denotes Reactin
T20309 39489-39504 Protein denotes IL-1RA promoter
T20308 39455-39462 Protein denotes CTA TCT
T20307 39435-39454 Protein denotes AAG GTA AAA TAT TTA
T20306 39423-39430 Protein denotes GGC GCA
T20305 39413-39421 Protein denotes NFATP2/3
T20304 39400-39407 Protein denotes AGT GGG
T20303 39384-39399 Protein denotes ATT GCG ACA CTT
T20302 39368-39383 Protein denotes TTA CAA CAG TGG
T20301 39360-39366 Protein denotes NFIL-6
T19782 38342-38346 Protein denotes IL-1
T19781 38298-38302 Protein denotes IL-2
T19780 38228-38234 Protein denotes TGFβ 1
T19779 38156-38160 Protein denotes IL-8
T19778 38145-38151 Protein denotes IL-1RA
T19777 38070-38074 Protein denotes IL-6
T19776 38061-38065 Protein denotes IL-1
T19775 38055-38059 Protein denotes TNFα
T19256 37688-37708 Protein denotes alkaline phosphatase
T19255 37493-37496 Protein denotes Rad
T19254 37397-37400 Protein denotes IgG
T21541 9336-9344 Protein denotes NFAT-DNA
T21540 9232-9236 Protein denotes IL-6
T21539 9226-9230 Protein denotes TNFα
T21538 9220-9224 Protein denotes IFNγ
T21537 9167-9192 Protein denotes NFκB-IL-8 oligonucleotide
T21536 9157-9163 Protein denotes NFIL-6
T21535 9151-9155 Protein denotes NFκB
T21534 9145-9149 Protein denotes NFAT
T21533 8976-8983 Binding denotes binding
T21532 8976-8983 Binding denotes binding
T21531 8976-8983 Binding denotes binding
T21530 9002-9008 Protein denotes NFIL-6
T21529 8993-8997 Protein denotes NFκB
T21528 8987-8991 Protein denotes NFAT
T21550 9669-9671 Protein denotes GP
T21549 9661-9667 Protein denotes TSST-1
T21548 9621-9625 Protein denotes NFκB
T21547 9506-9509 Protein denotes p50
T21546 9497-9500 Protein denotes p65
T21545 9478-9496 Protein denotes NFκB-IL-8-DNA-anti
T21544 9370-9391 Protein denotes NFκB-IL-8-DNA complex
T21543 9356-9366 Protein denotes NFIL-6-DNA
T21542 9346-9354 Protein denotes NFκB-DNA
T25563 23316-23326 Negative_regulation denotes Inhibition
T25562 23425-23427 Protein denotes GP
T25561 23374-23385 Protein denotes IL-1RA mRNA
T23902 18554-18561 Binding denotes binding
T23901 18554-18561 Binding denotes binding
T23900 18554-18561 Binding denotes binding
T23899 18589-18604 Protein denotes IL-1RA promoter
T23898 18571-18581 Protein denotes NFκB3 site
T23033 13297-13303 Protein denotes IL-1RA
T23032 12861-12871 Gene_expression denotes production
T23031 12854-12860 Protein denotes IL-1RA
T23030 12824-12830 Protein denotes TSST-1
T23029 12748-12754 Protein denotes IL-1RA
T23028 12652-12657 Protein denotes IL-1β
T23027 12467-12476 Negative_regulation denotes reduction
T23026 12486-12496 Gene_expression denotes production
T23025 12536-12542 Protein denotes TSST-1
T23024 12480-12485 Protein denotes IL-1β
T23023 12303-12313 Gene_expression denotes production
T23022 12297-12302 Protein denotes IL-1β
T23021 12199-12213 Negative_regulation denotes down-regulated
T23020 12267-12273 Protein denotes TSST-1
T23019 12189-12194 Protein denotes IL-1β
T21010 40525-40528 Protein denotes Fig
T18810 36587-36594 Binding denotes binding
T18809 36506-36511 Protein denotes Oct-1
T18808 36375-36379 Protein denotes NFκB
T17952 34702-34708 Protein denotes TSST-1
T17951 34695-34697 Protein denotes GP
T1973 2732-2740 Protein denotes Dectin-1
T1974 2779-2807 Protein denotes pattern recognition receptor
T1975 2809-2812 Protein denotes PRR
T1976 3007-3015 Protein denotes Dectin-1
T1977 3042-3046 Protein denotes TNFα
T1978 3055-3075 Protein denotes Toll-like receptor 2
T1979 2985-2992 Binding denotes binding
T1980 3028-3038 Gene_expression denotes production
T1981 3028-3038 Gene_expression denotes production
T1982 3016-3024 Positive_regulation denotes resulted
T1983 3016-3024 Positive_regulation denotes resulted
T1984 3193-3197 Protein denotes NFκB
T1985 3202-3208 Protein denotes NFIL-6
T1986 3184-3192 Positive_regulation denotes activate
T1987 3184-3192 Positive_regulation denotes activate
T1988 3298-3302 Protein denotes NFκB
T1989 3461-3465 Protein denotes IL-1
T1990 3467-3471 Protein denotes IL-6
T1991 3473-3477 Protein denotes TNFα
T1992 3420-3429 Localization denotes secretion
T1993 3420-3429 Localization denotes secretion
T1994 3420-3429 Localization denotes secretion
T1995 3565-3569 Protein denotes IL-1
T1996 3513-3523 Gene_expression denotes production
T1997 3771-3775 Protein denotes IL-8
T1998 3763-3770 Gene_expression denotes produce
T1999 4108-4112 Protein denotes NFκB
T2000 4136-4161 Protein denotes phosphoinositide-3-kinase
T2001 4163-4167 Protein denotes PI3K
T2002 4094-4104 Negative_regulation denotes inhibition
T2003 4904-4923 Protein denotes superantigen TSST-1
T2004 5048-5052 Protein denotes TNFα
T2005 5054-5059 Protein denotes IL-1β
T2006 5061-5071 Protein denotes IL-6, IL-8
T2007 5076-5082 Protein denotes IL-1RA
T2008 5108-5112 Protein denotes IFNγ
T2009 5114-5118 Protein denotes IL-2
T2010 5120-5124 Protein denotes IL-4
T2011 5126-5131 Protein denotes IL-10
T2012 5133-5138 Protein denotes IL-12
T2013 5143-5148 Protein denotes TGFβ1
T2014 5025-5035 Gene_expression denotes production
T2015 5025-5035 Gene_expression denotes production
T2016 5172-5182 Protein denotes NFκB sites
T2017 5228-5230 Protein denotes κ3
T2018 5289-5298 Protein denotes NFAT site
T2019 5308-5321 Protein denotes IFNγ promoter
T2020 5323-5327 Protein denotes ATP2
T2021 5446-5452 Protein denotes IL-1RA
T2022 5508-5523 Protein denotes IL-1RA promoter
T2023 5468-5475 Binding denotes binding
T2024 5627-5642 Protein denotes IL-1RA promoter
T2025 5654-5658 Protein denotes NFκB
T2026 5660-5664 Protein denotes PU.1
T10831 21843-21849 Protein denotes NFIL-6
T10830 21826-21838 Protein denotes NFAT via CyA
T10829 21807-21824 Protein denotes CAPE [35] and CyA
T2027 5669-5681 Protein denotes NFIL-6 sites
T2028 5596-5601 Entity denotes LRE-1
T2029 5822-5837 Protein denotes IL-1RA promoter
T10828 21798-21802 Protein denotes NFκB
T10827 21724-21732 Positive_regulation denotes relevant
T10826 21741-21750 Positive_regulation denotes induction
T10825 21764-21766 Protein denotes GP
T10824 21754-21760 Protein denotes IL-1RA
T10823 21704-21719 Protein denotes IL-1RA promoter
T10822 21583-21590 Negative_regulation denotes reduced
T10821 21591-21597 Protein denotes IL-1RA
T9955 20621-20629 Negative_regulation denotes decrease
T9954 20740-20754 Protein denotes GP/TSST-1 calc
T9953 20730-20736 Protein denotes TSST-1
T9952 20663-20667 Protein denotes IL-2
T9951 20637-20659 Protein denotes IL-1 dependent release
T9950 20497-20507 Gene_expression denotes production
T9949 20497-20507 Gene_expression denotes production
T9948 20526-20531 Protein denotes IL-1β
T9947 20511-20517 Protein denotes IL-1RA
T9946 20272-20278 Protein denotes TSST-1
T9945 20186-20192 Protein denotes IL-1RA
T9944 20180-20185 Protein denotes IL-1β
T9943 20005-20015 Positive_regulation denotes generating
T9942 20005-20015 Positive_regulation denotes generating
T9941 20032-20038 Protein denotes IL-1RA
T9940 20021-20026 Protein denotes IL-1β
T9939 19899-19905 Protein denotes IL-1RA
T9938 19893-19898 Protein denotes IL-1β
T9937 19784-19790 Protein denotes IL-1RA
T9936 19774-19779 Protein denotes IL-1β
T10854 22686-22696 Positive_regulation denotes pronounced
T10853 22797-22804 Localization denotes release
T10852 22704-22711 Binding denotes binding
T10851 22658-22668 Negative_regulation denotes inhibition
T10850 22790-22796 Protein denotes IL-1RA
T10849 22653-22657 Protein denotes NFκB
T10848 22587-22593 Gene_expression denotes levels
T10847 22587-22593 Gene_expression denotes levels
T10846 22624-22627 Protein denotes Fig
T10845 22608-22610 Protein denotes GP
T10844 22572-22586 Protein denotes IL-1RA protein
T10843 22448-22456 Negative_regulation denotes decrease
T10842 22528-22531 Protein denotes Fig
T10841 22460-22466 Protein denotes IL-1RA
T10840 22311-22325 Protein denotes highest IL-1RA
T10839 22247-22267 Protein denotes NFIL-6 binding sites
T10838 22238-22242 Protein denotes NFκB
T10837 21994-22003 Negative_regulation denotes reduction
T10836 21994-22003 Negative_regulation denotes reduction
T10835 21784-21794 Negative_regulation denotes inhibition
T10834 21784-21794 Negative_regulation denotes inhibition
T10833 22023-22037 Protein denotes IL-1RA protein
T10832 22007-22018 Protein denotes IL-1RA mRNA
T507 42-64 Protein denotes nuclear factors κB, AT
T508 69-73 Protein denotes IL-6
T509 119-138 Protein denotes IL-1β/IL-1 receptor
T510 31-38 Binding denotes binding
T511 31-38 Binding denotes binding
T512 17-26 Regulation denotes modulates
T513 17-26 Regulation denotes modulates
T514 645-666 Protein denotes nuclear factor (NF)κB
T518 771-775 Protein denotes IL-6
T519 777-800 Protein denotes tumor necrosis factor α
T520 804-816 Protein denotes interferon γ
T521 631-641 Positive_regulation denotes activation
T522 631-641 Positive_regulation denotes activation
T523 631-641 Positive_regulation denotes activation
T515 668-687 Protein denotes NFinterleukin(IL)-6
T516 692-696 Protein denotes NFAT
T517 764-769 Protein denotes IL-1β
T524 750-760 Gene_expression denotes production
T525 750-760 Gene_expression denotes production
T526 750-760 Gene_expression denotes production
T527 750-760 Gene_expression denotes production
T528 817-824 Positive_regulation denotes induced
T529 817-824 Positive_regulation denotes induced
T530 817-824 Positive_regulation denotes induced
T531 817-824 Positive_regulation denotes induced
T532 914-918 Protein denotes IL-8
T533 972-976 Protein denotes NFκB
T534 1004-1017 Protein denotes IL-8 promoter
T535 904-910 Gene_expression denotes amount
T536 961-968 Binding denotes binding
T537 961-968 Binding denotes binding
T538 882-889 Positive_regulation denotes induced
T539 1034-1046 Protein denotes IL-1receptor
T540 1162-1166 Protein denotes IL-8
T541 1231-1242 Protein denotes NFIL-6 site
T542 1253-1262 Protein denotes NFAT site
T543 1274-1289 Protein denotes IL-1RA promoter
T544 1212-1219 Binding denotes binding
T545 1212-1219 Binding denotes binding
T546 1301-1310 Positive_regulation denotes confirmed
T547 1192-1199 Positive_regulation denotes induced
T548 1192-1199 Positive_regulation denotes induced
T549 1507-1511 Protein denotes NFκB
T550 1513-1519 Protein denotes NFIL-6
T551 1524-1528 Protein denotes NFAT
T552 1567-1573 Protein denotes IL-1RA
T553 1496-1503 Binding denotes binding
T554 1496-1503 Binding denotes binding
T555 1496-1503 Binding denotes binding
T556 1555-1563 Positive_regulation denotes increase
T557 1451-1459 Positive_regulation denotes elevated
T558 1451-1459 Positive_regulation denotes elevated
T559 1451-1459 Positive_regulation denotes elevated
T560 1669-1674 Protein denotes IL-1β
T561 1679-1683 Protein denotes IL-6
T562 1656-1665 Negative_regulation denotes reduction
T563 1656-1665 Negative_regulation denotes reduction
T564 1867-1871 Protein denotes IL-1
T565 1896-1900 Protein denotes IL-2
T566 1882-1892 Gene_expression denotes production
T567 1837-1846 Negative_regulation denotes decreased
T568 2199-2210 Protein denotes IL-1RA gene
T569 2181-2191 Regulation denotes regulation
T3704 5871-5875 Protein denotes NFκB
T3705 5877-5883 Protein denotes NFIL-6
T3706 5888-5892 Protein denotes NFAT
T3707 5916-5920 Protein denotes TNFα
T3708 5922-5926 Protein denotes IL-6
T3709 5931-5945 Protein denotes IFNγ promoters
T3710 5857-5867 Positive_regulation denotes activities
T3711 6079-6083 Protein denotes NFκB
T3712 6098-6104 Protein denotes NFIL-6
T3713 6161-6177 Protein denotes κ1, κ2, κ3 sites
T3714 6187-6200 Protein denotes TNFα promoter
T3715 6223-6236 Protein denotes IL-8 promoter
T3716 6238-6253 Protein denotes NFIL-6consensus
T3717 6263-6285 Protein denotes IL-6 promoter; Table 1
T3718 6287-6294 Protein denotes Fig. 1A
T3719 6068-6075 Binding denotes binding
T3720 6068-6075 Binding denotes binding
T3721 6068-6075 Binding denotes binding
T3722 6068-6075 Binding denotes binding
T3723 6446-6450 Protein denotes NFκB
T3724 6475-6488 Protein denotes IL-8 promoter
T3725 6539-6547 Protein denotes NFκB p65
T3726 6574-6577 Protein denotes p50
T3727 6579-6586 Protein denotes Fig. 1A
T3728 6528-6535 Binding denotes binding
T3729 6528-6535 Binding denotes binding
T3730 6528-6535 Binding denotes binding
T6287 15691-15699 Positive_regulation denotes increase
T6286 15798-15813 Negative_regulation denotes down-regulation
T6285 15691-15699 Positive_regulation denotes increase
T6284 15708-15718 Gene_expression denotes production
T6283 15881-15895 Protein denotes GP/TSST-1 calc
T6282 15871-15877 Protein denotes TSST-1
T6281 15703-15707 Protein denotes IFNγ
T6280 15603-15613 Gene_expression denotes production
T6279 15598-15602 Protein denotes IFNγ
T6278 15454-15463 Localization denotes secretion
T6277 15449-15453 Protein denotes TNFα
T6276 15280-15286 Regulation denotes change
T6275 15296-15306 Gene_expression denotes production
T6274 15291-15295 Protein denotes TNFα
T6273 15147-15157 Gene_expression denotes production
T6272 15142-15146 Protein denotes TNFα
T6271 15009-15016 Positive_regulation denotes induced
T6270 15009-15016 Positive_regulation denotes induced
T6269 15044-15050 Protein denotes IL-1RA
R2314 T3755 T3757 themeOf NFATc1,binding
R259 T507 T510 themeOf "nuclear factors κB, AT",binding
R260 T508 T511 themeOf IL-6,binding
R261 T510 T512 themeOf binding,modulates
R262 T511 T513 themeOf binding,modulates
R263 T514 T521 themeOf nuclear factor (NF)κB,activation
R264 T515 T522 themeOf NFinterleukin(IL)-6,activation
R265 T516 T523 themeOf NFAT,activation
R266 T517 T524 themeOf IL-1β,production
R267 T518 T525 themeOf IL-6,production
R268 T519 T526 themeOf tumor necrosis factor α,production
R269 T520 T527 themeOf interferon γ,production
R270 T524 T528 themeOf production,induced
R271 T525 T529 themeOf production,induced
R272 T526 T530 themeOf production,induced
R273 T527 T531 themeOf production,induced
R274 T532 T535 themeOf IL-8,amount
R275 T532 T536 themeOf IL-8,binding
R276 T533 T536 themeOf NFκB,binding
R277 T533 T537 themeOf NFκB,binding
R278 T534 T537 themeOf IL-8 promoter,binding
R279 T535 T538 themeOf amount,induced
R280 T542 T544 themeOf NFAT site,binding
R281 T543 T545 themeOf IL-1RA promoter,binding
R282 T543 T546 themeOf IL-1RA promoter,confirmed
R283 T544 T547 themeOf binding,induced
R284 T545 T548 themeOf binding,induced
R285 T549 T553 themeOf NFκB,binding
R286 T550 T554 themeOf NFIL-6,binding
R287 T551 T555 themeOf NFAT,binding
R288 T552 T556 themeOf IL-1RA,increase
R289 T553 T557 themeOf binding,elevated
R290 T554 T558 themeOf binding,elevated
R291 T555 T559 themeOf binding,elevated
R292 T560 T562 themeOf IL-1β,reduction
R293 T561 T563 themeOf IL-6,reduction
R294 T565 T566 themeOf IL-2,production
R295 T566 T567 themeOf production,decreased
R296 T568 T569 themeOf IL-1RA gene,regulation
R7635 T11941 T11944 themeOf NFκB,binding
R7636 T11942 T11945 themeOf NFIL-6,binding
R7637 T11943 T11946 themeOf NFAT,binding
R7638 T11944 T11947 themeOf binding,induced
R7639 T11945 T11948 themeOf binding,induced
R7640 T11946 T11949 themeOf binding,induced
R7641 T11950 T11951 themeOf NFAT,binding
R7870 T12234 T12238 themeOf NFκB p65,binding
R7871 T12235 T12238 themeOf p50,binding
R7872 T12239 T12241 themeOf IL-8,transcription
R7873 T12240 T12242 themeOf NFκB p65/65 homodimer,activation
R7874 T12241 T12243 themeOf transcription,induction
R7875 T12244 T12248 themeOf NFκB p65,transactivated
R7876 T12246 T12249 themeOf NFATc2,binding
R7877 T12246 T12250 themeOf NFATc2,binding
R7878 T12247 T12250 themeOf IL-8κB site,binding
R7879 T12256 T12258 themeOf NFκB,binding
R7880 T12258 T12259 themeOf binding,regulating
R7881 T12259 T12260 themeOf regulating,supporting
R7882 T12261 T12263 themeOf IL-1β,induce
R7883 T12262 T12264 themeOf IL-1RA,induced
R7884 T12265 T12269 partOf IL-1RA promoter,[34
R7885 T12270 T12283 causeOf GP,leads
R7886 T12271 T12278 themeOf IL-1RA,production
R7887 T12272 T12279 themeOf NFATP2/3,induction
R7888 T12272 T12281 themeOf NFATP2/3,binding
R7889 T12273 T12280 themeOf NFIL-6 DNA,binding
R7890 T12273 T12281 themeOf NFIL-6 DNA,binding
R7891 T12275 T12282 causeOf NFAT,due
R7892 T12278 T12283 themeOf production,leads
R7893 T12279 T12282 themeOf induction,due
R7894 T12280 T12284 themeOf binding,induction
R7895 T12281 T12285 themeOf binding,induction
R7896 T12286 T12293 themeOf NFκB,decrease
R7897 T12287 T12294 themeOf NFAT,decrease
R7898 T12288 T12295 themeOf NFIL-6,decrease
R7899 T12291 T12296 themeOf IL-1RA,induction
R7900 T12292 T12297 themeOf Fig,induction
R7901 T12298 T12300 themeOf IL-8,produce
R7902 T12299 T12301 themeOf IL-1RA,produce
R7903 T12304 T12412 themeOf TNFα [43],expression
R7904 T12414 T12420 themeOf TSST-1,binding
R7905 T12415 T12420 themeOf MHC-II molecules,binding
R7906 T12416 T12421 themeOf "T cell receptor, leading to release of mainly IFNγ",kinase
R7907 T12417 T12422 themeOf TNFα,kinase
R7908 T12418 T12423 themeOf PI3K,kinase
R7909 T12419 T12424 themeOf p38,kinase
R7910 T12425 T12426 themeOf IL-8,induction
R7911 T12429 T12432 themeOf IL-1β,down-regulation
R7912 T12430 T12433 themeOf IL-6,down-regulation
R7913 T12431 T12434 themeOf IL-1RA,up-regulation
R7914 T12432 T12435 themeOf down-regulation,altered
R7915 T12433 T12436 themeOf down-regulation,altered
R7916 T12447 T12449 themeOf NFκB,binding
R7917 T12447 T12450 themeOf NFκB,binding
R7918 T12448 T12450 themeOf TNFα promoter,binding
R7919 T12453 T12455 themeOf NFκB3,binding
R7920 T12455 T12456 themeOf binding,increased
R7921 T12457 T12470 causeOf TSST-1,induced
R7922 T12457 T12471 causeOf TSST-1,induced
R7923 T12458 T12463 themeOf NFκB,binding
R7924 T12458 T12464 themeOf NFκB,binding
R7925 T12459 T12464 themeOf TNFα promoter,binding
R7926 T12460 T12465 themeOf NFκB3,up-regulation
R7927 T12461 T12466 themeOf NFκB,up-regulation
R7928 T12462 T12467 themeOf IL-1RA promoter,up-regulation
R7929 T12463 T12468 themeOf binding,down-regulation
R7930 T12463 T12470 themeOf binding,induced
R7931 T12464 T12469 themeOf binding,down-regulation
R7932 T12464 T12471 themeOf binding,induced
R7933 T12484 T12486 themeOf NFIL-6 site [32],binding
R7934 T12486 T12487 themeOf binding,increase
R7935 T12488 T12489 themeOf IL-1β/IL-1RA,decrease
R7936 T12493 T12494 themeOf IL-1β,inactivated
R7937 T12499 T12501 themeOf sIL-1RA,production
R7938 T12500 T12502 themeOf IL-1β,production
R7939 T12501 T12503 themeOf production,controls
R7940 T12502 T12504 themeOf production,controls
R7941 T12506 T12507 themeOf NFAT,activation
R7942 T12508 T12511 themeOf NFκB,Activation
R7943 T12513 T12516 causeOf LPS,activated
R7944 T12514 T12517 causeOf peptidoglycan,activated
R7945 T12515 T12516 themeOf IL-1RA,activated
R7946 T12515 T12517 themeOf IL-1RA,activated
R11628 T17274 T17276 themeOf IL-1RA promoter,binding
R11629 T17274 T17278 themeOf IL-1RA promoter,regulated
R11630 T17275 T17277 themeOf Fig,binding
R11631 T17275 T17279 themeOf Fig,regulated
R12657 T18502 T18508 partOf P2 site,promoter
R12658 T18503 T18508 partOf IFNγ,promoter
R12659 T18506 T18509 themeOf NFAT,binding
R12660 T18507 T18510 themeOf NFκB proteins,binding
R12661 T18509 T18511 themeOf binding,crucial
R12662 T18510 T18512 themeOf binding,crucial
R14762 T21528 T21531 themeOf NFAT,binding
R14763 T21529 T21532 themeOf NFκB,binding
R14764 T21530 T21533 themeOf NFIL-6,binding
R14765 T21548 T21551 themeOf NFκB,binding
R16888 T24877 T24879 themeOf IL-1β,alterations
R16889 T24878 T24880 themeOf IL-1RA,alterations
R16890 T24884 T24886 themeOf IL-1RA,production
R16891 T24885 T24887 themeOf IL-1β,production
R17297 T25548 T25552 themeOf NFκB,Inhibition
R17298 T25548 T25555 themeOf NFκB,binding
R17299 T25549 T25553 themeOf NFAT,Inhibition
R17300 T25549 T25556 themeOf NFAT,binding
R17301 T25551 T25554 themeOf IL-1RA promoter,binding
R17302 T25551 T25555 themeOf IL-1RA promoter,binding
R17303 T25551 T25556 themeOf IL-1RA promoter,binding
R17304 T25558 T25563 themeOf NFκB,Inhibition
R17305 T25561 T25564 themeOf IL-1RA mRNA,decreased
R17306 T25566 T25570 themeOf NFκB,Inhibition
R17307 T25567 T25572 causeOf NFAT,reduced
R17308 T25568 T25573 causeOf NFIL-6,reduced
R17309 T25569 T25571 themeOf IL-1RA,production
R17310 T25571 T25572 themeOf production,reduced
R17311 T25571 T25573 themeOf production,reduced
R1070 T2004 T2014 themeOf TNFα,production
R1071 T2005 T2015 themeOf IL-1β,production
R1072 T2022 T2023 themeOf IL-1RA promoter,binding
R1080 T1984 T1986 themeOf NFκB,activate
R1081 T1985 T1987 themeOf NFIL-6,activate
R1082 T1989 T1992 themeOf IL-1,secretion
R1083 T2024 T2028 partOf IL-1RA promoter,LRE-1
R1084 T2027 T2028 partOf NFIL-6 sites,LRE-1
R1085 T2025 T2028 partOf NFκB,LRE-1
R2283 T3709 T3710 themeOf IFNγ promoters,activities
R2284 T3711 T3719 themeOf NFκB,binding
R2302 T3736 T3739 themeOf NFκB p65,binding
R2303 T3736 T3740 themeOf NFκB p65,binding
R2304 T3737 T3740 themeOf p50,binding
R2305 T3738 T3741 themeOf p52,negative
R2306 T3742 T3745 themeOf NFκB,binding
R2307 T3742 T3746 themeOf NFκB,binding
R2308 T3743 T3746 themeOf TNFα promoter,binding
R2309 T3744 T3747 themeOf NFκB,binding
R2310 T3747 T3748 themeOf binding,decreased
R2311 T3749 T3752 themeOf NFAT,binding
R2312 T3751 T3752 themeOf Fig. 1A,binding
R2313 T3754 T3757 themeOf NFATc2,binding
R3876 T6272 T6273 themeOf TNFα,production
R3877 T6274 T6275 themeOf TNFα,production
R3879 T6275 T6276 themeOf production,change
R3880 T6218 T6222 themeOf IL-8,production
R3881 T6277 T6278 themeOf TNFα,secretion
R3882 T6219 T6223 themeOf IL-6,production
R3883 T6220 T6224 themeOf IFNγ,production
R3884 T6225 T6226 themeOf IL-1β,production
R3885 T6279 T6280 themeOf IFNγ,production
R3886 T6227 T6228 themeOf IL-1β,production
R3887 T6228 T6229 themeOf production,up-regulation
R3888 T6230 T6232 themeOf IL-1β,reduction
R3889 T6281 T6284 themeOf IFNγ,production
R3890 T6233 T6234 themeOf IL-1β,reduction
R3891 T6284 T6285 themeOf production,increase
R3892 T6235 T6237 themeOf IL-6,induced
R3893 T6236 T6238 themeOf IL-6,production
R3894 T6238 T6239 themeOf production,LPS-induced
R3895 T6239 T6240 themeOf LPS-induced,alteration
R3896 T6285 T6286 themeOf increase,down-regulation
R3897 T6241 T6243 themeOf IL-6,production
R3898 T6286 T6287 themeOf down-regulation,increase
R3899 T6243 T6244 themeOf production,decreased
R3900 T6292 T6296 themeOf IL-2,production
R3901 T6247 T6249 themeOf IL-8,produced
R3902 T6248 T6250 themeOf IL-1RA,produced
R3903 T6251 T6252 themeOf IL-1RA,production
R3904 T6252 T6253 themeOf production,alter
R3905 T6254 T6256 themeOf IL-1RA,production
R3906 T6293 T6297 themeOf "IL-12, IL-4",production
R3907 T6256 T6257 themeOf production,increase
R3908 T6294 T6298 themeOf IL-10,production
R3909 T6258 T6259 themeOf IL-1RA,elevated
R3910 T6295 T6299 themeOf TGFβ 1,production
R3911 T6260 T6262 themeOf IL-8,productions
R3912 T6261 T6263 themeOf IL-1RA,productions
R3913 T6262 T6264 themeOf productions,GP-induced
R3914 T6263 T6265 themeOf productions,GP-induced
R3915 T6296 T6300 themeOf production,induced
R3916 T6297 T6301 themeOf production,induced
R3917 T6268 T6270 themeOf IL-8,induced
R3918 T6298 T6302 themeOf production,induced
R3919 T6299 T6303 themeOf production,induced
R5662 T8700 T8704 themeOf NFIL-6,binding
R5663 T8701 T8703 themeOf NFAT,binding
R5664 T8701 T8704 themeOf NFAT,binding
R5665 T8702 T8705 themeOf IL-1RA,expression
R5666 T8703 T8706 themeOf binding,Role
R5667 T8704 T8707 themeOf binding,Role
R5668 T8705 T8708 themeOf expression,TSST-1-induced
R5669 T8714 T8715 themeOf IL-1RA promoter,bind
R5670 T8717 T8719 themeOf TSST-1,binding
R5671 T8720 T8721 themeOf κB,Binding
R5672 T8721 T8722 themeOf Binding,elevated
R5673 T8723 T8724 themeOf NFIL-6 site,binding
R5674 T8724 T8725 themeOf binding,up-regulation
R5675 T8726 T8727 themeOf NFIL-6 site,binding
R5676 T8727 T8728 themeOf binding,increased
R5677 T8729 T8730 themeOf NFATP2/3,binding
R5678 T8730 T8731 themeOf binding,increase
R6533 T9940 T9942 themeOf IL-1β,generating
R6534 T9941 T9943 themeOf IL-1RA,generating
R6535 T9947 T9949 themeOf IL-1RA,production
R6536 T9948 T9950 themeOf IL-1β,production
R6537 T9951 T9955 themeOf IL-1 dependent release,decrease
R7115 T10821 T10822 themeOf IL-1RA,reduced
R7116 T10824 T10826 themeOf IL-1RA,induction
R7117 T10825 T10826 causeOf GP,induction
R7118 T10826 T10827 themeOf induction,relevant
R7119 T10828 T10834 themeOf NFκB,inhibition
R7120 T10829 T10835 themeOf CAPE [35] and CyA,inhibition
R7121 T10832 T10836 themeOf IL-1RA mRNA,reduction
R7122 T10833 T10837 themeOf IL-1RA protein,reduction
R7123 T10841 T10843 themeOf IL-1RA,decrease
R7124 T10844 T10847 themeOf IL-1RA protein,levels
R7125 T10845 T10848 themeOf GP,levels
R7126 T10849 T10851 themeOf NFκB,inhibition
R7127 T10849 T10852 themeOf NFκB,binding
R7128 T10850 T10853 themeOf IL-1RA,release
R7129 T10852 T10854 themeOf binding,pronounced
R7130 T10853 T10855 themeOf release,decreased
R1073 T1976 T1979 themeOf Dectin-1,binding
R1074 T1977 T1980 themeOf TNFα,production
R1075 T1978 T1981 themeOf Toll-like receptor 2,production
R1076 T1979 T1982 causeOf binding,resulted
R1077 T1979 T1983 causeOf binding,resulted
R1078 T1980 T1982 themeOf production,resulted
R1079 T1981 T1983 themeOf production,resulted
R1065 T1990 T1993 themeOf IL-6,secretion
R1066 T1991 T1994 themeOf TNFα,secretion
R1067 T1995 T1996 themeOf IL-1,production
R1068 T1997 T1998 themeOf IL-8,produce
R1069 T1999 T2002 themeOf NFκB,inhibition
R2285 T3711 T3720 themeOf NFκB,binding
R2286 T3712 T3721 themeOf NFIL-6,binding
R2287 T3712 T3722 themeOf NFIL-6,binding
R2288 T3716 T3719 themeOf NFIL-6consensus,binding
R2289 T3716 T3721 themeOf NFIL-6consensus,binding
R2290 T3718 T3720 themeOf Fig. 1A,binding
R2291 T3718 T3722 themeOf Fig. 1A,binding
R2292 T3725 T3728 themeOf NFκB p65,binding
R2293 T3725 T3729 themeOf NFκB p65,binding
R2294 T3725 T3730 themeOf NFκB p65,binding
R2295 T3726 T3729 themeOf p50,binding
R2297 T3727 T3730 themeOf Fig. 1A,binding
R2296 T3726 T3731 themeOf p50,degree
R2298 T3727 T3732 themeOf Fig. 1A,degree
R2299 T3728 T3733 themeOf binding,degree
R2300 T3729 T3734 themeOf binding,degree
R2301 T3730 T3735 themeOf binding,degree
R2315 T3755 T3758 themeOf NFATc1,degree
R2316 T3757 T3759 themeOf binding,degree
R3878 T6217 T6221 themeOf TNFα,production
R3875 T6269 T6271 themeOf IL-1RA,induced
R12865 T18809 T18810 themeOf Oct-1,binding
R15326 T22409 T22414 themeOf NFκB,binding
R15327 T22409 T22419 themeOf NFκB,binding
R15328 T22410 T22415 themeOf p65,binding
R15329 T22410 T22419 themeOf p65,binding
R15330 T22411 T22416 themeOf p50,binding
R15331 T22412 T22417 themeOf NFATc2,binding
R15332 T22413 T22418 themeOf c1,binding
R15333 T22425 T22433 themeOf NFκB p50,positive
R15334 T22426 T22434 themeOf p65,positive
R15335 T22427 T22435 themeOf for NFATc1,positive
R15336 T22429 T22436 themeOf NFκB p65,positive
R15337 T22430 T22437 themeOf p50,positive
R15338 T22431 T22438 themeOf NFAT c2,positive
R15339 T22432 T22439 themeOf c1,positive
R15652 T23019 T23021 themeOf IL-1β,down-regulated
R15653 T23022 T23023 themeOf IL-1β,production
R15654 T23024 T23026 themeOf IL-1β,production
R15655 T23026 T23027 themeOf production,reduction
R15656 T23031 T23032 themeOf IL-1RA,production
R16256 T23898 T23900 themeOf NFκB3 site,binding
R16257 T23898 T23902 themeOf NFκB3 site,binding
R16258 T23899 T23901 themeOf IL-1RA promoter,binding
R16259 T23899 T23902 themeOf IL-1RA promoter,binding
R16474 T24240 T24242 themeOf NFAT-DNA,binding
R16475 T24242 T24243 themeOf binding,elevated
R16885 T24869 T24871 themeOf IL-1β/IL-1RA,Decreased
R16886 T24873 T24875 themeOf IL-1β,generating
R16887 T24874 T24876 themeOf IL-1RA,generating

testone

Id Subject Object Predicate Lexical cue
T36 119-124 Protein denotes IL-1β
T37 125-149 Protein denotes IL-1 receptor antagonist
T38 572-600 Protein denotes toxic shock syndrome toxin 1
T39 602-608 Protein denotes TSST-1
T40 668-687 Protein denotes NFinterleukin(IL)-6
T41 692-696 Protein denotes NFAT
T42 715-721 Protein denotes TSST-1
T43 764-769 Protein denotes IL-1β
T44 771-775 Protein denotes IL-6
T45 777-800 Protein denotes tumor necrosis factor α
T46 804-816 Protein denotes interferon γ
T47 914-918 Protein denotes IL-8
T48 1004-1008 Protein denotes IL-8
T49 1034-1057 Protein denotes IL-1receptor antagonist
T50 1058-1060 Protein denotes RA
T51 1162-1166 Protein denotes IL-8
T52 1274-1280 Protein denotes IL-1RA
T53 1385-1391 Protein denotes TSST-1
T54 1477-1483 Protein denotes TSST-1
T55 1513-1519 Protein denotes NFIL-6
T56 1524-1528 Protein denotes NFAT
T57 1567-1573 Protein denotes IL-1RA
T58 1615-1621 Protein denotes TSST-1
T59 1669-1674 Protein denotes IL-1β
T60 1679-1683 Protein denotes IL-6
T61 1732-1738 Protein denotes TSST-1
T62 1747-1752 Protein denotes IL-1β
T63 1753-1759 Protein denotes IL-1RA
T64 1851-1857 Protein denotes TSST-1
T65 1867-1871 Protein denotes IL-1
T66 1896-1900 Protein denotes IL-2
T67 2102-2108 Protein denotes IL-1RA
T68 2199-2205 Protein denotes IL-1RA
T69 31-38 Binding denotes binding
T70 139-149 Negative_regulation denotes antagonist
T71 750-760 Gene_expression denotes production
T72 817-824 Positive_regulation denotes induced
T73 882-889 Positive_regulation denotes induced
T74 961-968 Binding denotes binding
T75 1009-1017 Entity denotes promoter
T76 1022-1030 Positive_regulation denotes increase
T77 1047-1057 Negative_regulation denotes antagonist
T78 1062-1072 Gene_expression denotes production
T79 1192-1199 Positive_regulation denotes induced
T80 1212-1219 Binding denotes binding
T81 1231-1242 Entity denotes NFIL-6 site
T82 1258-1262 Entity denotes site
T83 1281-1289 Entity denotes promoter
T84 1451-1459 Positive_regulation denotes elevated
T85 1484-1491 Positive_regulation denotes induced
T86 1496-1503 Binding denotes binding
T87 1555-1563 Positive_regulation denotes increase
T88 1656-1665 Negative_regulation denotes reduction
T89 1739-1746 Positive_regulation denotes induced
T90 1837-1846 Negative_regulation denotes decreased
T91 1858-1865 Positive_regulation denotes induced
T92 1872-1881 Positive_regulation denotes dependent
T93 1882-1892 Gene_expression denotes production
T94 2181-2191 Regulation denotes regulation
T95 2225-2234 Regulation denotes modulated
T35 69-73 Protein denotes IL-6
T26181 27870-27876 Protein denotes IL-1RA
T25443 22847-22851 Protein denotes NFAT
T25465 23596-23605 Positive_regulation denotes following
T25464 23561-23571 Gene_expression denotes production
T25463 23549-23556 Negative_regulation denotes reduced
T25462 23386-23395 Positive_regulation denotes following
T25461 23364-23373 Negative_regulation denotes decreased
T25460 23352-23360 Positive_regulation denotes resulted
T25459 23197-23204 Binding denotes binding
T25458 23185-23193 Negative_regulation denotes decrease
T25457 23167-23171 Entity denotes site
T25456 22889-22897 Entity denotes promoter
T25455 22867-22874 Binding denotes binding
T25454 22833-22840 Positive_regulation denotes induced
T25453 22816-22826 Negative_regulation denotes Inhibition
T25452 23575-23581 Protein denotes IL-1RA
T25451 23528-23534 Protein denotes NFIL-6
T25450 23519-23523 Protein denotes NFAT
T25449 23429-23434 Protein denotes GAPDH
T25448 23374-23380 Protein denotes IL-1RA
T25447 23345-23351 Protein denotes NFIL-6
T25446 23336-23340 Protein denotes NFAT
T25445 22882-22888 Protein denotes IL-1RA
T25444 22856-22862 Protein denotes NFIL-6
T24777 21450-21460 Gene_expression denotes production
T24776 21443-21449 Positive_regulation denotes higher
T24775 21068-21076 Positive_regulation denotes resulted
T24774 20932-20941 Positive_regulation denotes following
T24773 20840-20849 Positive_regulation denotes following
T24772 20811-20820 Negative_regulation denotes Decreased
T24771 21479-21484 Protein denotes IL-1β
T24770 21464-21470 Protein denotes IL-1RA
T24769 21300-21306 Protein denotes TSST-1
T24768 21279-21285 Protein denotes TSST-1
T24767 21266-21272 Protein denotes TSST-1
T24766 21226-21232 Protein denotes IL-1RA
T24765 21220-21225 Protein denotes IL-1β
T24764 21107-21113 Protein denotes IL-1RA
T24763 21096-21101 Protein denotes IL-1β
T24762 21027-21033 Protein denotes TSST-1
T24761 21014-21020 Protein denotes TSST-1
T24760 20977-20983 Protein denotes TSST-1
T24759 20919-20925 Protein denotes IL-1RA
T24758 20913-20918 Protein denotes IL-1β
T24757 20879-20885 Protein denotes TSST-1
T24756 20855-20861 Protein denotes TSST-1
T24755 20827-20833 Protein denotes IL-1RA
T24754 20821-20826 Protein denotes IL-1β
T24169 19264-19271 Binding denotes binding
T24168 19246-19254 Positive_regulation denotes elevated
T24167 18982-18994 Positive_regulation denotes up-regulated
T24166 18970-18977 Binding denotes Binding
T24165 18915-18922 Binding denotes binding
T24164 18903-18910 Positive_regulation denotes induced
T24163 18886-18895 Regulation denotes modulated
T24162 19648-19654 Protein denotes TSST-1
T24161 19609-19615 Protein denotes TSST-1
T24160 19379-19385 Protein denotes TSST-1
T24159 19300-19306 Protein denotes IL-1RA
T24158 19255-19259 Protein denotes NFAT
T24157 19177-19183 Protein denotes TSST-1
T24156 19160-19166 Protein denotes TSST-1
T24155 19085-19091 Protein denotes TSST-1
T24154 19017-19023 Protein denotes TSST-1
T24153 18953-18959 Protein denotes IL-1RA
T24152 18896-18902 Protein denotes TSST-1
T23861 18606-18613 Binding denotes Binding
T23860 18577-18581 Entity denotes site
T23859 18554-18561 Binding denotes binding
T23858 18546-18553 Positive_regulation denotes induced
T23857 18520-18529 Regulation denotes modulated
T23856 18710-18716 Protein denotes TSST-1
T23855 18679-18685 Protein denotes TSST-1
T23854 18649-18655 Protein denotes TSST-1
T23853 18589-18595 Protein denotes IL-1RA
T23852 18539-18545 Protein denotes TSST-1
T22903 13111-13121 Gene_expression denotes production
T22902 13097-13103 Positive_regulation denotes higher
T22901 12861-12871 Gene_expression denotes production
T22900 12771-12780 Positive_regulation denotes following
T22899 12497-12506 Positive_regulation denotes following
T22898 12486-12496 Gene_expression denotes production
T22897 12467-12476 Negative_regulation denotes reduction
T22896 12303-12313 Gene_expression denotes production
T22895 12228-12237 Positive_regulation denotes following
T22894 12199-12213 Negative_regulation denotes down-regulated
T22893 13297-13303 Protein denotes IL-1RA
T22892 13270-13276 Protein denotes TSST-1
T22891 13176-13182 Protein denotes TSST-1
T22890 13104-13110 Protein denotes IL-1RA
T22889 13054-13060 Protein denotes TSST-1
T22888 12956-12962 Protein denotes TSST-1
T22887 12943-12949 Protein denotes TSST-1
T22886 12854-12860 Protein denotes IL-1RA
T22885 12824-12830 Protein denotes TSST-1
T22884 12786-12792 Protein denotes TSST-1
T22883 12748-12754 Protein denotes IL-1RA
T22882 12652-12657 Protein denotes IL-1β
T22881 12623-12629 Protein denotes TSST-1
T22880 12536-12542 Protein denotes TSST-1
T22879 12512-12518 Protein denotes TSST-1
T22878 12480-12485 Protein denotes IL-1β
T22877 12398-12404 Protein denotes TSST-1
T22876 12385-12391 Protein denotes TSST-1
T22875 12297-12302 Protein denotes IL-1β
T22874 12267-12273 Protein denotes TSST-1
T22873 12243-12249 Protein denotes TSST-1
T22872 12189-12194 Protein denotes IL-1β
T22334 10581-10589 Gene_expression denotes positive
T22333 10274-10281 Binding denotes binding
T22332 10740-10742 Protein denotes c1
T22331 10731-10738 Protein denotes NFAT c2
T22330 10723-10726 Protein denotes p50
T22329 10718-10721 Protein denotes p65
T22328 10624-10626 Protein denotes c2
T22327 10616-10622 Protein denotes NFATc1
T22326 10604-10607 Protein denotes p65
T22325 10599-10602 Protein denotes p50
T22324 10529-10534 Protein denotes c-rel
T22323 10524-10527 Protein denotes p52
T22322 10379-10383 Protein denotes NFAT
T22321 10239-10241 Protein denotes c1
T22320 10232-10238 Protein denotes NFATc2
T22319 10224-10227 Protein denotes p50
T22318 10220-10223 Protein denotes p65
T20972 40720-40726 Protein denotes TSST-1
T20971 40707-40713 Protein denotes TSST-1
T20970 40435-40441 Protein denotes TSST-1
T20969 40422-40428 Protein denotes TSST-1
T21413 9610-9617 Binding denotes binding
T21412 8976-8983 Binding denotes binding
T21411 8965-8968 Positive_regulation denotes led
T21410 9947-9953 Protein denotes TSST-1
T21409 9765-9771 Protein denotes TSST-1
T21408 9739-9745 Protein denotes TSST-1
T21407 9676-9682 Protein denotes TSST-1
T21406 9661-9667 Protein denotes TSST-1
T21405 9641-9647 Protein denotes TSST-1
T21404 9506-9509 Protein denotes p50
T21403 9497-9500 Protein denotes p65
T21402 9483-9487 Protein denotes IL-8
T21401 9375-9379 Protein denotes IL-8
T21400 9356-9362 Protein denotes NFIL-6
T21399 9336-9340 Protein denotes NFAT
T21398 9241-9245 Protein denotes IL-8
T21397 9232-9236 Protein denotes IL-6
T21396 9226-9230 Protein denotes TNFα
T21395 9220-9224 Protein denotes IFNγ
T21394 9172-9176 Protein denotes IL-8
T21393 9157-9163 Protein denotes NFIL-6
T21392 9145-9149 Protein denotes NFAT
T21391 9002-9008 Protein denotes NFIL-6
T21390 8987-8991 Protein denotes NFAT
T20241 38877-38885 Entity denotes promoter
T20240 38830-38837 Binding denotes binding
T20239 39932-39938 Protein denotes IL-1RA
T20238 39682-39687 Protein denotes GAPDH
T20237 39671-39677 Protein denotes IL-1RA
T20236 39489-39495 Protein denotes IL-1RA
T20235 39420-39421 Protein denotes 3
T20234 39413-39419 Protein denotes NFATP2
T20233 39360-39366 Protein denotes NFIL-6
T20232 38870-38876 Protein denotes IL-1RA
T19724 38342-38346 Protein denotes IL-1
T19723 38298-38302 Protein denotes IL-2
T19722 38228-38234 Protein denotes TGFβ 1
T19721 38156-38160 Protein denotes IL-8
T19720 38145-38151 Protein denotes IL-1RA
T19719 38070-38074 Protein denotes IL-6
T19718 38061-38065 Protein denotes IL-1
T19717 38055-38059 Protein denotes TNFα
T19716 38049-38053 Protein denotes IFNγ
T19185 37240-37246 Protein denotes NFATc1
T19184 37212-37218 Protein denotes NFATc2
T19183 37186-37191 Protein denotes c-rel
T19182 37127-37130 Protein denotes p52
T19181 37101-37104 Protein denotes p65
T19180 37073-37076 Protein denotes p50
T19179 36967-36972 Protein denotes c-Rel
T19178 36944-36947 Protein denotes p52
T19177 36686-36690 Protein denotes NFAT
T18779 36587-36594 Binding denotes binding
T18778 36201-36208 Binding denotes binding
T18777 36506-36511 Protein denotes Oct-1
T18776 36400-36402 Protein denotes 50
T18775 36396-36399 Protein denotes p65
T18250 35517-35524 Binding denotes binding
T18249 35501-35508 Positive_regulation denotes crucial
T18248 35327-35336 Negative_regulation denotes Mutations
T18247 35241-35248 Binding denotes binding
T18246 35528-35532 Protein denotes NFAT
T18245 35417-35421 Protein denotes TNFα
T18244 35359-35363 Protein denotes IFNγ
T18243 34889-34893 Protein denotes IL-6
T18242 34880-34884 Protein denotes IFNγ
T18241 34874-34878 Protein denotes IL-8
T18240 34868-34872 Protein denotes TNFα
T17934 34702-34708 Protein denotes TSST-1
T17933 34454-34460 Protein denotes TSST-1
T17459 33002-33016 Phosphorylation denotes phosphorylated
T17091 32595-32602 Binding denotes binding
T17090 32271-32278 Positive_regulation denotes induced
T17089 32946-32952 Protein denotes IL-1RA
T17088 32940-32945 Protein denotes IL-1β
T17087 32654-32660 Protein denotes IL-1RA
T17086 32457-32463 Protein denotes IL-1RA
T17085 32427-32433 Protein denotes TSST-1
T17084 32377-32383 Protein denotes TSST-1
T11465 24769-24777 Positive_regulation denotes mediated
T11464 24441-24451 Positive_regulation denotes activation
T11463 24388-24395 Binding denotes binding
T11462 24271-24278 Binding denotes binding
T11461 24263-24270 Positive_regulation denotes induced
T11460 32024-32030 Protein denotes IL-1RA
T11459 31698-31702 Protein denotes NFAT
T11458 31602-31607 Protein denotes IL-1β
T11457 31587-31593 Protein denotes IL-1RA
T11456 31362-31368 Protein denotes TSST-1
T11455 31346-31352 Protein denotes TSST-1
T11454 31095-31099 Protein denotes IL-2
T11453 31080-31084 Protein denotes IL-1
T11452 31064-31070 Protein denotes TSST-1
T11451 30993-30998 Protein denotes IL-1β
T11450 30919-30925 Protein denotes TSST-1
T11449 30891-30897 Protein denotes IL-1RA
T11448 30885-30890 Protein denotes IL-1β
T11447 30851-30855 Protein denotes IL-1
T11446 30805-30810 Protein denotes IL-1β
T11445 30793-30799 Protein denotes IL-1RA
T11444 30702-30708 Protein denotes TSST-1
T11443 30674-30680 Protein denotes IL-1RA
T11442 30668-30673 Protein denotes IL-1β
T11441 30552-30558 Protein denotes IL-1RA
T11440 30537-30543 Protein denotes TSST-1
T11439 30364-30370 Protein denotes TSST-1
T11438 30158-30164 Protein denotes TSST-1
T11437 29948-29954 Protein denotes IL-1RA
T11436 29647-29653 Protein denotes IL-1RA
T11435 29634-29638 Protein denotes TNFα
T11434 29432-29438 Protein denotes IL-1RA
T11433 29349-29353 Protein denotes TNFα
T11432 29305-29311 Protein denotes TSST-1
T11431 29149-29155 Protein denotes TSST-1
T11430 29096-29102 Protein denotes TSST-1
T11429 29068-29074 Protein denotes IL-1RA
T11428 28960-28966 Protein denotes IL-1RA
T11427 28945-28951 Protein denotes TSST-1
T11426 28869-28873 Protein denotes TNFα
T11425 28820-28826 Protein denotes TSST-1
T11424 28774-28778 Protein denotes IFNγ
T11423 28766-28770 Protein denotes IL-6
T11422 28759-28764 Protein denotes IL-1β
T11421 28753-28757 Protein denotes TNFα
T11420 28722-28728 Protein denotes IL-1RA
T11419 28713-28717 Protein denotes IL-8
T11418 28660-28664 Protein denotes NFAT
T11417 28649-28655 Protein denotes NFIL-6
T11416 28617-28623 Protein denotes TSST-1
T11415 28540-28546 Protein denotes IL-1RA
T11414 28476-28480 Protein denotes IL-6
T11413 28466-28471 Protein denotes IL-1β
T11412 28386-28392 Protein denotes IL-1RA
T11411 28380-28385 Protein denotes IL-1β
T11410 28365-28371 Protein denotes TSST-1
T11409 28201-28207 Protein denotes TSST-1
T11408 27682-27688 Protein denotes IL-1RA
T11407 27651-27655 Protein denotes IL-8
T11406 27548-27576 Protein denotes p38 mitogen-activated kinase
T11405 27512-27516 Protein denotes TNFα
T11404 27503-27507 Protein denotes IFNγ
T11403 27388-27394 Protein denotes TSST-1
T11402 27347-27351 Protein denotes TNFα
T11401 27222-27242 Protein denotes Toll-like receptor 4
T11400 27161-27167 Protein denotes TSST-1
T11399 27076-27082 Protein denotes TSST-1
T11398 26946-26952 Protein denotes IL-1RA
T11397 26933-26937 Protein denotes IL-8
T11396 26822-26828 Protein denotes IL-1RA
T11395 26708-26714 Protein denotes IL-1RA
T11394 26543-26549 Protein denotes IL-1RA
T11393 26513-26519 Protein denotes IL-1RA
T11392 26482-26488 Protein denotes NFIL-6
T11391 26473-26477 Protein denotes NFAT
T11390 26421-26427 Protein denotes IL-1RA
T11389 26412-26416 Protein denotes IL-6
T11388 26406-26410 Protein denotes IFNγ
T11387 26388-26392 Protein denotes NFAT
T11386 26254-26260 Protein denotes NFIL-6
T11385 26248-26249 Protein denotes 3
T11384 26241-26247 Protein denotes NFATP2
T11383 25923-25929 Protein denotes IL-1RA
T11382 25842-25848 Protein denotes IL-1RA
T11381 25811-25816 Protein denotes IL-1β
T11380 25771-25777 Protein denotes TSST-1
T11379 25583-25588 Protein denotes IL-1β
T11378 25574-25578 Protein denotes TNFα
T11377 25499-25502 Protein denotes p65
T11376 25451-25455 Protein denotes IL-8
T11375 25409-25413 Protein denotes IL-8
T11374 25381-25387 Protein denotes NFATc2
T11373 25363-25369 Protein denotes NFIL-6
T11372 25355-25358 Protein denotes p65
T11371 25283-25287 Protein denotes IL-8
T11370 25249-25253 Protein denotes IL-8
T11369 25188-25190 Protein denotes 50
T11368 25184-25187 Protein denotes p65
T11367 25154-25156 Protein denotes 65
T11366 25150-25153 Protein denotes p65
T11365 25095-25099 Protein denotes IL-8
T11364 25000-25004 Protein denotes IL-8
T11363 24966-24969 Protein denotes p50
T11362 24936-24939 Protein denotes p65
T11361 24797-24803 Protein denotes IL-1RA
T11360 24778-24782 Protein denotes IL-8
T11359 24668-24674 Protein denotes IL-1RA
T11358 24659-24663 Protein denotes IL-8
T11357 24473-24477 Protein denotes NFAT
T11356 24383-24387 Protein denotes NFAT
T11355 24301-24305 Protein denotes NFAT
T11354 24289-24295 Protein denotes NFIL-6
T11556 32010-32019 Positive_regulation denotes activated
T11555 31684-31694 Positive_regulation denotes activation
T11554 31668-31676 Regulation denotes involved
T11553 31608-31618 Gene_expression denotes production
T11552 31100-31110 Gene_expression denotes production
T11551 31085-31094 Regulation denotes dependent
T11550 31071-31078 Positive_regulation denotes induced
T11549 31052-31059 Negative_regulation denotes reduced
T11548 31014-31025 Negative_regulation denotes inactivated
T11547 30965-30977 Negative_regulation denotes unreasonable
T11546 30904-30913 Positive_regulation denotes following
T11545 30840-30847 Regulation denotes effects
T11544 30783-30789 Negative_regulation denotes excess
T11543 30687-30696 Positive_regulation denotes following
T11542 30652-30660 Negative_regulation denotes decrease
T11541 30559-30569 Gene_expression denotes production
T11540 30544-30551 Positive_regulation denotes induced
T11539 30516-30529 Positive_regulation denotes up-regulation
T11538 30379-30386 Binding denotes binding
T11537 30371-30378 Positive_regulation denotes induced
T11536 30201-30208 Regulation denotes altered
T11535 30173-30180 Binding denotes binding
T11534 30165-30172 Positive_regulation denotes induced
T11533 30130-30141 Negative_regulation denotes regulations
T11532 30125-30129 Negative_regulation denotes down
T11531 29814-29821 Binding denotes binding
T11530 29654-29662 Entity denotes promoter
T11529 29603-29621 Entity denotes NFκB binding motif
T11528 29593-29602 Entity denotes decameric
T11527 29377-29390 Positive_regulation denotes up-regulation
T11526 29325-29332 Binding denotes binding
T11525 29312-29319 Positive_regulation denotes induced
T11524 29269-29284 Negative_regulation denotes down-regulation
T11523 29216-29225 Positive_regulation denotes increased
T11522 29164-29171 Binding denotes binding
T11521 29156-29163 Positive_regulation denotes induced
T11520 29120-29127 Binding denotes binding
T11519 29112-29119 Positive_regulation denotes induced
T11518 28967-28977 Gene_expression denotes production
T11517 28952-28959 Positive_regulation denotes induced
T11516 28835-28842 Binding denotes binding
T11515 28827-28834 Positive_regulation denotes induced
T11514 28729-28737 Entity denotes promoter
T11513 28632-28639 Binding denotes binding
T11512 28624-28631 Positive_regulation denotes induced
T11511 28523-28536 Positive_regulation denotes up-regulation
T11510 28447-28462 Negative_regulation denotes down-regulation
T11509 28372-28379 Positive_regulation denotes induced
T11508 28353-28360 Regulation denotes altered
T11507 27612-27621 Positive_regulation denotes induction
T11506 27485-27492 Localization denotes release
T11505 27408-27415 Binding denotes binding
T11504 26953-26967 Positive_regulation denotes in response to
T11503 26925-26932 Gene_expression denotes produce
T11502 26814-26821 Gene_expression denotes produce
T11501 26695-26704 Positive_regulation denotes induction
T11500 26681-26690 Positive_regulation denotes necessary
T11499 26567-26574 Positive_regulation denotes induced
T11498 26520-26528 Entity denotes promoter
T11497 26500-26505 Entity denotes sites
T11496 26489-26496 Binding denotes binding
T11495 26455-26463 Negative_regulation denotes decrease
T11494 26428-26436 Entity denotes promoter
T11493 26323-26328 Entity denotes motif
T11492 26315-26322 Binding denotes binding
T11491 26289-26292 Positive_regulation denotes due
T11490 26265-26272 Binding denotes binding
T11489 26228-26237 Positive_regulation denotes induction
T11488 26193-26203 Gene_expression denotes production
T11487 26184-26189 Positive_regulation denotes leads
T11486 25834-25841 Positive_regulation denotes induced
T11485 25804-25810 Positive_regulation denotes induce
T11484 25637-25644 Binding denotes binding
T11483 25621-25631 Regulation denotes regulating
T11482 25516-25520 Entity denotes site
T11481 25503-25510 Binding denotes binding
T11480 25416-25420 Entity denotes site
T11479 25394-25401 Binding denotes binding
T11478 25388-25393 Binding denotes dimer
T11477 25288-25301 Transcription denotes transcription
T11476 25274-25282 Positive_regulation denotes mediated
T11475 25254-25267 Transcription denotes transcription
T11474 25240-25248 Positive_regulation denotes mediated
T11473 25127-25137 Positive_regulation denotes activation
T11472 25100-25113 Transcription denotes transcription
T11471 25082-25091 Positive_regulation denotes induction
T11470 25005-25013 Entity denotes promoter
T11469 24976-24992 Entity denotes B consensus site
T11468 24920-24927 Binding denotes binding
T11467 24899-24907 Positive_regulation denotes mediated
T11466 24804-24814 Gene_expression denotes production
T10395 22797-22804 Localization denotes release
T10394 22780-22789 Negative_regulation denotes decreased
T10393 22771-22774 Positive_regulation denotes led
T10392 22704-22711 Binding denotes binding
T10391 22448-22456 Negative_regulation denotes decrease
T10390 22091-22098 Binding denotes binding
T10389 22069-22078 Negative_regulation denotes reduction
T10388 21994-22003 Negative_regulation denotes reduction
T10387 21981-21986 Entity denotes sites
T10386 21921-21928 Binding denotes binding
T10385 21906-21920 Negative_regulation denotes down-regulated
T10384 21876-21885 Negative_regulation denotes overruled
T10383 21831-21834 Positive_regulation denotes via
T10382 21741-21750 Positive_regulation denotes induction
T10381 21680-21686 Entity denotes factor
T10380 21583-21590 Negative_regulation denotes reduced
T10379 22790-22796 Protein denotes IL-1RA
T10378 22572-22578 Protein denotes IL-1RA
T10377 22460-22466 Protein denotes IL-1RA
T10376 22319-22325 Protein denotes IL-1RA
T10375 22023-22029 Protein denotes IL-1RA
T10374 22007-22013 Protein denotes IL-1RA
T10373 21974-21980 Protein denotes IL-1RA
T10372 21843-21849 Protein denotes NFIL-6
T10371 21826-21830 Protein denotes NFAT
T10370 21754-21760 Protein denotes IL-1RA
T10369 21704-21710 Protein denotes IL-1RA
T10368 21591-21597 Protein denotes IL-1RA
T9502 20691-20700 Positive_regulation denotes following
T9501 20652-20659 Localization denotes release
T9500 20642-20651 Regulation denotes dependent
T9499 20621-20629 Negative_regulation denotes decrease
T9498 20497-20507 Gene_expression denotes production
T9497 20490-20496 Positive_regulation denotes higher
T9496 19993-20001 Positive_regulation denotes resulted
T9495 19682-19689 Positive_regulation denotes induced
T9494 19661-19670 Regulation denotes modulated
T9493 20743-20749 Protein denotes TSST-1
T9492 20730-20736 Protein denotes TSST-1
T9491 20706-20712 Protein denotes TSST-1
T9490 20663-20667 Protein denotes IL-2
T9489 20637-20641 Protein denotes IL-1
T9488 20526-20531 Protein denotes IL-1β
T9487 20511-20517 Protein denotes IL-1RA
T9486 20332-20338 Protein denotes TSST-1
T9485 20310-20316 Protein denotes TSST-1
T9484 20272-20278 Protein denotes TSST-1
T9483 20186-20192 Protein denotes IL-1RA
T9482 20180-20185 Protein denotes IL-1β
T9481 20032-20038 Protein denotes IL-1RA
T9480 20021-20026 Protein denotes IL-1β
T9479 19899-19905 Protein denotes IL-1RA
T9478 19893-19898 Protein denotes IL-1β
T9477 19784-19790 Protein denotes IL-1RA
T9476 19774-19779 Protein denotes IL-1β
T9475 19696-19702 Protein denotes IL-1RA
T9474 19690-19695 Protein denotes IL-1β
T9473 19675-19681 Protein denotes TSST-1
T7949 18348-18356 Positive_regulation denotes elevated
T7948 18246-18250 Entity denotes site
T7947 18222-18229 Binding denotes binding
T7946 18121-18128 Binding denotes binding
T7945 17974-17981 Binding denotes binding
T7944 17882-17886 Entity denotes site
T7943 17879-17880 Entity denotes -
T7942 17860-17867 Binding denotes binding
T7941 17850-17859 Positive_regulation denotes increased
T7940 17839-17846 Positive_regulation denotes induced
T7939 17722-17729 Binding denotes binding
T7938 17547-17561 Negative_regulation denotes down-regulated
T7937 17522-17526 Entity denotes site
T7936 17497-17504 Binding denotes binding
T7935 17489-17496 Positive_regulation denotes induced
T7934 17405-17413 Positive_regulation denotes elevated
T7933 17328-17335 Binding denotes Binding
T7932 17131-17138 Binding denotes binding
T7931 16981-16988 Binding denotes binding
T7930 16971-16980 Positive_regulation denotes increased
T7929 16607-16612 Entity denotes sites
T7928 16482-16486 Binding denotes bind
T7927 16304-16314 Gene_expression denotes expression
T7926 16289-16296 Positive_regulation denotes induced
T7925 16232-16239 Binding denotes binding
T7924 16202-16206 Regulation denotes Role
T7923 18336-18342 Protein denotes TSST-1
T7922 18301-18307 Protein denotes TSST-1
T7921 17906-17912 Protein denotes TSST-1
T7920 17832-17838 Protein denotes TSST-1
T7919 17468-17474 Protein denotes TSST-1
T7918 17423-17429 Protein denotes TSST-1
T7917 17291-17297 Protein denotes TSST-1
T7916 17230-17236 Protein denotes TSST-1
T7915 17096-17102 Protein denotes TSST-1
T7914 17000-17006 Protein denotes TSST-1
T7913 16620-16626 Protein denotes IL-1RA
T7912 16503-16509 Protein denotes IL-1RA
T7911 16413-16417 Protein denotes IFNγ
T7910 16405-16409 Protein denotes IL-6
T7909 16399-16403 Protein denotes TNFα
T7908 16297-16303 Protein denotes IL-1RA
T7907 16282-16288 Protein denotes TSST-1
T7906 16249-16255 Protein denotes TSST-1
T7905 16227-16231 Protein denotes NFAT
T7904 16216-16222 Protein denotes NFIL-6
T4483 11055-11059 Positive_regulation denotes lead
T4482 16160-16166 Protein denotes TSST-1
T4481 16147-16153 Protein denotes TSST-1
T4480 16103-16109 Protein denotes TSST-1
T4479 16001-16007 Protein denotes TGFβ 1
T4478 15991-15996 Protein denotes IL-10
T4477 15985-15989 Protein denotes IL-4
T4476 15978-15983 Protein denotes IL-12
T4475 15972-15976 Protein denotes IL-2
T4474 15948-15953 Protein denotes TGFβ1
T4473 15941-15946 Protein denotes IL-10
T4472 15935-15939 Protein denotes IL-4
T4471 15928-15933 Protein denotes IL-12
T4470 15922-15926 Protein denotes IL-2
T4469 15884-15890 Protein denotes TSST-1
T4468 15871-15877 Protein denotes TSST-1
T4467 15829-15835 Protein denotes TSST-1
T4466 15703-15707 Protein denotes IFNγ
T4465 15598-15602 Protein denotes IFNγ
T4464 15590-15594 Protein denotes IFNγ
T4463 15449-15453 Protein denotes TNFα
T4462 15392-15398 Protein denotes TSST-1
T4461 15379-15385 Protein denotes TSST-1
T4460 15291-15295 Protein denotes TNFα
T4459 15142-15146 Protein denotes TNFα
T4458 15121-15125 Protein denotes TNFα
T4457 15044-15050 Protein denotes IL-1RA
T4456 15035-15039 Protein denotes IL-8
T4455 14924-14930 Protein denotes IL-1RA
T4454 14915-14919 Protein denotes IL-8
T4453 14814-14820 Protein denotes IL-1RA
T4452 14805-14809 Protein denotes IL-8
T4451 14725-14731 Protein denotes IL-1RA
T4450 14700-14706 Protein denotes TSST-1
T4449 14620-14626 Protein denotes TSST-1
T4448 14539-14545 Protein denotes TSST-1
T4447 14485-14491 Protein denotes IL-1RA
T4446 14443-14449 Protein denotes TSST-1
T4445 14400-14406 Protein denotes IL-1RA
T4444 14164-14170 Protein denotes IL-1RA
T4443 14158-14162 Protein denotes IL-8
T4442 14143-14149 Protein denotes IL-1RA
T4441 14096-14102 Protein denotes TSST-1
T4440 14083-14089 Protein denotes TSST-1
T4439 14059-14065 Protein denotes TSST-1
T4438 14028-14032 Protein denotes IL-8
T4437 13936-13940 Protein denotes IL-8
T4436 13775-13779 Protein denotes IL-8
T4435 13731-13735 Protein denotes IL-8
T4434 13626-13632 Protein denotes TSST-1
T4433 13613-13619 Protein denotes TSST-1
T4432 13589-13595 Protein denotes TSST-1
T4431 13564-13568 Protein denotes IL-6
T4430 13500-13504 Protein denotes IL-6
T4429 13436-13440 Protein denotes IL-6
T4428 13397-13401 Protein denotes IL-6
T4427 12146-12151 Protein denotes IL-1β
T4426 12121-12127 Protein denotes TSST-1
T4425 12039-12045 Protein denotes TSST-1
T4424 12001-12007 Protein denotes TSST-1
T4423 11932-11937 Protein denotes IL-1β
T4422 11889-11895 Protein denotes TSST-1
T4421 11813-11818 Protein denotes IL-1β
T4420 11704-11709 Protein denotes IL-1β
T4419 11685-11690 Protein denotes IL-1β
T4418 11671-11677 Protein denotes TSST-1
T4417 11095-11099 Protein denotes IFNγ
T4416 11089-11093 Protein denotes IL-6
T4415 11083-11087 Protein denotes IL-8
T4414 11077-11081 Protein denotes TNFα
T4413 10981-10985 Protein denotes IFNγ
T4412 10972-10976 Protein denotes IL-6
T4411 10966-10970 Protein denotes IL-8
T4410 10960-10964 Protein denotes TNFα
T4409 10891-10897 Protein denotes TSST-1
T4408 10861-10867 Protein denotes TSST-1
T4528 16016-16023 Positive_regulation denotes induced
T4527 15958-15968 Gene_expression denotes production
T4526 15798-15813 Negative_regulation denotes down-regulation
T4525 15719-15728 Positive_regulation denotes following
T4524 15708-15718 Gene_expression denotes production
T4523 15691-15699 Positive_regulation denotes increase
T4522 15629-15638 Positive_regulation denotes following
T4521 15603-15613 Gene_expression denotes production
T4520 15439-15445 Regulation denotes effect
T4519 15296-15306 Gene_expression denotes production
T4518 15280-15286 Regulation denotes change
T4517 15009-15016 Positive_regulation denotes induced
T4516 14979-14988 Regulation denotes dependent
T4515 14821-14832 Gene_expression denotes productions
T4514 14797-14804 Positive_regulation denotes induced
T4513 14707-14714 Positive_regulation denotes induced
T4512 14687-14695 Positive_regulation denotes elevated
T4511 14492-14502 Gene_expression denotes production
T4510 14473-14481 Positive_regulation denotes increase
T4509 14407-14417 Gene_expression denotes production
T4508 14368-14373 Regulation denotes alter
T4507 14203-14211 Gene_expression denotes produced
T4506 14044-14053 Positive_regulation denotes following
T4505 14033-14043 Gene_expression denotes production
T4504 14014-14024 Negative_regulation denotes alteration
T4503 13941-13951 Gene_expression denotes production
T4502 13924-13932 Positive_regulation denotes increase
T4501 13894-13902 Positive_regulation denotes resulted
T4500 13780-13790 Gene_expression denotes production
T4499 13763-13774 Positive_regulation denotes substantial
T4498 13753-13760 Positive_regulation denotes induced
T4497 13569-13579 Gene_expression denotes production
T4496 13554-13563 Negative_regulation denotes decreased
T4495 13505-13515 Gene_expression denotes production
T4494 13492-13499 Positive_regulation denotes induced
T4493 13470-13480 Negative_regulation denotes alteration
T4492 13405-13412 Positive_regulation denotes induced
T4491 12128-12135 Positive_regulation denotes induced
T4490 12104-12113 Negative_regulation denotes reduction
T4489 11919-11928 Negative_regulation denotes reduction
T4488 11819-11829 Gene_expression denotes production
T4487 11796-11809 Positive_regulation denotes up-regulation
T4486 11732-11741 Positive_regulation denotes following
T4485 11710-11720 Gene_expression denotes production
T4484 11063-11073 Gene_expression denotes production
T948 2732-2740 Protein denotes Dectin-1
T949 3007-3015 Protein denotes Dectin-1
T950 3042-3046 Protein denotes TNFα
T951 3055-3075 Protein denotes Toll-like receptor 2
T952 3100-3105 Protein denotes MyD88
T953 3202-3208 Protein denotes NFIL-6
T954 3461-3465 Protein denotes IL-1
T955 3467-3471 Protein denotes IL-6
T956 3473-3477 Protein denotes TNFα
T957 3549-3555 Protein denotes IL-1RA
T958 3565-3569 Protein denotes IL-1
T959 3771-3775 Protein denotes IL-8
T960 4917-4923 Protein denotes TSST-1
T961 5048-5052 Protein denotes TNFα
T962 5054-5059 Protein denotes IL-1β
T963 5061-5065 Protein denotes IL-6
T964 5067-5071 Protein denotes IL-8
T965 5076-5082 Protein denotes IL-1RA
T966 5108-5112 Protein denotes IFNγ
T967 5114-5118 Protein denotes IL-2
T968 5120-5124 Protein denotes IL-4
T969 5126-5131 Protein denotes IL-10
T970 5133-5138 Protein denotes IL-12
T971 5143-5148 Protein denotes TGFβ1
T972 5192-5196 Protein denotes TNFα
T973 5266-5270 Protein denotes IL-8
T974 5308-5312 Protein denotes IFNγ
T975 5371-5375 Protein denotes IL-6
T976 5446-5452 Protein denotes IL-1RA
T977 5508-5514 Protein denotes IL-1RA
T978 5627-5633 Protein denotes IL-1RA
T979 5822-5828 Protein denotes IL-1RA
T980 2620-2628 Positive_regulation denotes mediated
T981 2985-2992 Binding denotes binding
T982 3016-3024 Positive_regulation denotes resulted
T983 3028-3038 Gene_expression denotes production
T984 3513-3523 Gene_expression denotes production
T985 3631-3638 Positive_regulation denotes induced
T986 3763-3770 Gene_expression denotes produce
T987 3776-3790 Positive_regulation denotes in response to
T988 4385-4392 Regulation denotes effects
T989 5271-5279 Entity denotes promoter
T990 5294-5298 Entity denotes site
T991 5468-5475 Binding denotes binding
T992 5515-5523 Entity denotes promoter
T3036 5877-5883 Protein denotes NFIL-6
T3037 5888-5892 Protein denotes NFAT
T3038 5916-5920 Protein denotes TNFα
T3039 5922-5926 Protein denotes IL-6
T3040 5931-5935 Protein denotes IFNγ
T3041 5996-6002 Protein denotes TSST-1
T3042 6026-6032 Protein denotes TSST-1
T3043 6098-6104 Protein denotes NFIL-6
T3044 6187-6191 Protein denotes TNFα
T3045 6223-6227 Protein denotes IL-8
T3046 6263-6267 Protein denotes IL-6
T3047 6397-6403 Protein denotes TSST-1
T3048 6475-6479 Protein denotes IL-8
T3049 6544-6547 Protein denotes p65
T3050 6574-6577 Protein denotes p50
T3051 6689-6692 Protein denotes p65
T3052 6718-6721 Protein denotes p50
T3053 6731-6734 Protein denotes p52
T3054 6863-6867 Protein denotes TNFα
T3055 6934-6940 Protein denotes TSST-1
T3056 6979-6985 Protein denotes TSST-1
T3057 7063-7069 Protein denotes TSST-1
T3058 7100-7106 Protein denotes TSST-1
T3059 7130-7136 Protein denotes TSST-1
T3060 7235-7239 Protein denotes NFAT
T3061 7261-7265 Protein denotes IFNγ
T3062 7308-7312 Protein denotes NFAT
T3063 7359-7365 Protein denotes NFATc2
T3064 7392-7398 Protein denotes NFATc1
T3065 5849-5856 Binding denotes Binding
T3066 5936-5945 Entity denotes promoters
T3067 5946-5955 Positive_regulation denotes following
T3068 6068-6075 Binding denotes binding
T3069 6327-6334 Positive_regulation denotes induced
T3070 6508-6515 Positive_regulation denotes induced
T3071 6528-6535 Binding denotes binding
T3072 6673-6680 Binding denotes binding
T3073 6808-6814 Regulation denotes change
T3074 6823-6830 Positive_regulation denotes induced
T3075 6836-6843 Binding denotes binding
T3076 6920-6929 Negative_regulation denotes decreased
T3077 6941-6948 Positive_regulation denotes induced
T3078 6954-6961 Binding denotes binding
T3079 7168-7174 Positive_regulation denotes induce
T3080 7201-7208 Binding denotes binding
T3081 7266-7274 Entity denotes promoter
T3082 7340-7347 Positive_regulation denotes induced
T3083 7348-7355 Binding denotes binding
R1 T39 T38 equivalentTo TSST-1,toxic shock syndrome toxin 1
R2 T43 T71 themeOf IL-1β,production
R3 T44 T71 themeOf IL-6,production
R5 T46 T71 themeOf interferon γ,production
R6 T49 T78 themeOf IL-1receptor antagonist,production
R7 T50 T49 equivalentTo RA,IL-1receptor antagonist
R8 T51 T76 causeOf IL-8,increase
R9 T54 T85 causeOf TSST-1,induced
R10 T55 T86 themeOf NFIL-6,binding
R11 T56 T86 themeOf NFAT,binding
R12 T57 T87 themeOf IL-1RA,increase
R13 T59 T88 themeOf IL-1β,reduction
R14 T60 T88 themeOf IL-6,reduction
R15 T61 T89 causeOf TSST-1,induced
R16 T62 T89 themeOf IL-1β,induced
R17 T63 T89 themeOf IL-1RA,induced
R18 T64 T91 causeOf TSST-1,induced
R19 T65 T92 causeOf IL-1,dependent
R20 T66 T93 themeOf IL-2,production
R21 T68 T94 themeOf IL-1RA,regulation
R22 T71 T72 themeOf production,induced
R23 T75 T74 themeOf promoter,binding
R24 T75 T48 partOf promoter,IL-8
R25 T77 T76 themeOf antagonist,increase
R26 T78 T76 themeOf production,increase
R27 T80 T79 themeOf binding,induced
R28 T81 T80 themeOf NFIL-6 site,binding
R29 T81 T52 partOf NFIL-6 site,IL-1RA
R30 T83 T80 themeOf promoter,binding
R31 T83 T52 partOf promoter,IL-1RA
R32 T84 T85 themeOf elevated,induced
R33 T85 T84 themeOf induced,elevated
R34 T86 T84 themeOf binding,elevated
R35 T86 T85 themeOf binding,induced
R36 T91 T90 themeOf induced,decreased
R37 T92 T90 themeOf dependent,decreased
R38 T93 T92 themeOf production,dependent
R55 T35 T69 themeOf IL-6,binding
R356 T949 T981 themeOf Dectin-1,binding
R357 T950 T983 themeOf TNFα,production
R358 T951 T983 themeOf Toll-like receptor 2,production
R359 T952 T983 themeOf MyD88,production
R360 T957 T984 themeOf IL-1RA,production
R361 T958 T984 themeOf IL-1,production
R362 T959 T986 themeOf IL-8,produce
R363 T976 T991 themeOf IL-1RA,binding
R364 T981 T982 causeOf binding,resulted
R365 T983 T982 themeOf production,resulted
R366 T984 T985 themeOf production,induced
R367 T986 T987 themeOf produce,in response to
R368 T989 T973 partOf promoter,IL-8
R369 T992 T991 themeOf promoter,binding
R370 T992 T977 partOf promoter,IL-1RA
R7422 T11354 T11462 themeOf NFIL-6,binding
R7423 T11355 T11462 themeOf NFAT,binding
R7424 T11356 T11463 themeOf NFAT,binding
R7425 T11357 T11464 themeOf NFAT,activation
R7426 T11360 T11466 themeOf IL-8,production
R7427 T11360 T11465 themeOf IL-8,mediated
R7428 T11361 T11466 themeOf IL-1RA,production
R7429 T11362 T11468 themeOf p65,binding
R7430 T11365 T11472 themeOf IL-8,transcription
R7431 T11370 T11475 themeOf IL-8,transcription
R7432 T11371 T11477 themeOf IL-8,transcription
R7433 T11372 T11479 themeOf p65,binding
R7434 T11373 T11476 causeOf NFIL-6,mediated
R7435 T11373 T11479 themeOf NFIL-6,binding
R7436 T11377 T11481 themeOf p65,binding
R7437 T11380 T11485 causeOf TSST-1,induce
R7438 T11381 T11485 themeOf IL-1β,induce
R7439 T11382 T11486 themeOf IL-1RA,induced
R7440 T11384 T11490 themeOf NFATP2,binding
R7441 T11385 T11490 themeOf 3,binding
R7442 T11386 T11490 themeOf NFIL-6,binding
R7443 T11391 T11496 themeOf NFAT,binding
R7444 T11392 T11496 themeOf NFIL-6,binding
R7445 T11395 T11501 themeOf IL-1RA,induction
R7446 T11396 T11502 themeOf IL-1RA,produce
R7447 T11397 T11504 themeOf IL-8,in response to
R7448 T11397 T11503 themeOf IL-8,produce
R7449 T11398 T11503 themeOf IL-1RA,produce
R7450 T11398 T11504 themeOf IL-1RA,in response to
R7451 T11403 T11505 themeOf TSST-1,binding
R7452 T11404 T11506 themeOf IFNγ,release
R7453 T11405 T11506 themeOf TNFα,release
R7454 T11407 T11507 themeOf IL-8,induction
R7455 T11408 T11507 themeOf IL-1RA,induction
R7456 T11410 T11509 causeOf TSST-1,induced
R7457 T11411 T11509 themeOf IL-1β,induced
R7458 T11412 T11509 themeOf IL-1RA,induced
R7459 T11413 T11510 themeOf IL-1β,down-regulation
R7460 T11414 T11510 themeOf IL-6,down-regulation
R7461 T11415 T11511 themeOf IL-1RA,up-regulation
R7462 T11417 T11513 themeOf NFIL-6,binding
R7463 T11418 T11513 themeOf NFAT,binding
R7464 T11425 T11515 causeOf TSST-1,induced
R7465 T11427 T11517 causeOf TSST-1,induced
R7466 T11428 T11518 themeOf IL-1RA,production
R7467 T11429 T11520 themeOf IL-1RA,binding
R7468 T11432 T11525 causeOf TSST-1,induced
R7469 T11432 T11524 themeOf TSST-1,down-regulation
R7470 T11436 T11531 themeOf IL-1RA,binding
R7471 T11438 T11535 themeOf TSST-1,binding
R7472 T11438 T11534 causeOf TSST-1,induced
R7473 T11439 T11537 causeOf TSST-1,induced
R7474 T11440 T11540 causeOf TSST-1,induced
R7475 T11441 T11541 themeOf IL-1RA,production
R7476 T11442 T11542 themeOf IL-1β,decrease
R7477 T11443 T11542 themeOf IL-1RA,decrease
R7478 T11444 T11542 causeOf TSST-1,decrease
R7479 T11444 T11543 causeOf TSST-1,following
R7480 T11445 T11544 themeOf IL-1RA,excess
R7481 T11447 T11545 themeOf IL-1,effects
R7482 T11450 T11546 causeOf TSST-1,following
R7483 T11452 T11550 causeOf TSST-1,induced
R7484 T11453 T11551 causeOf IL-1,dependent
R7485 T11454 T11552 themeOf IL-2,production
R7486 T11458 T11553 themeOf IL-1β,production
R7487 T11459 T11555 themeOf NFAT,activation
R7488 T11460 T11556 themeOf IL-1RA,activated
R7489 T11462 T11461 themeOf binding,induced
R7490 T11466 T11465 themeOf production,mediated
R7491 T11468 T11467 themeOf binding,mediated
R7492 T11470 T11364 partOf promoter,IL-8
R7493 T11472 T11471 themeOf transcription,induction
R7494 T11475 T11474 themeOf transcription,mediated
R7495 T11477 T11476 themeOf transcription,mediated
R7496 T11484 T11483 themeOf binding,regulating
R7497 T11488 T11487 themeOf production,leads
R7498 T11490 T11489 themeOf binding,induction
R7499 T11492 T11491 causeOf binding,due
R7500 T11494 T11390 partOf promoter,IL-1RA
R7501 T11496 T11495 themeOf binding,decrease
R7502 T11496 T11499 themeOf binding,induced
R7503 T11498 T11496 themeOf promoter,binding
R7504 T11498 T11393 partOf promoter,IL-1RA
R7505 T11501 T11500 themeOf induction,necessary
R7506 T11503 T11504 themeOf produce,in response to
R7507 T11509 T11508 themeOf induced,altered
R7508 T11510 T11508 themeOf down-regulation,altered
R7509 T11513 T11512 themeOf binding,induced
R7510 T11514 T11420 partOf promoter,IL-1RA
R7511 T11514 T11513 themeOf promoter,binding
R7512 T11516 T11515 themeOf binding,induced
R7513 T11518 T11517 themeOf production,induced
R7514 T11520 T11519 themeOf binding,induced
R7515 T11522 T11521 themeOf binding,induced
R7516 T11522 T11523 themeOf binding,increased
R7517 T11525 T11524 themeOf induced,down-regulation
R7518 T11526 T11524 themeOf binding,down-regulation
R7519 T11526 T11525 themeOf binding,induced
R7520 T11529 T11435 partOf NFκB binding motif,TNFα
R7521 T11529 T11436 partOf NFκB binding motif,IL-1RA
R7522 T11530 T11436 partOf promoter,IL-1RA
R7523 T11535 T11534 themeOf binding,induced
R7524 T11535 T11536 themeOf binding,altered
R7525 T11538 T11537 themeOf binding,induced
R7526 T11540 T11539 themeOf induced,up-regulation
R7527 T11541 T11540 themeOf production,induced
R7528 T11541 T11539 themeOf production,up-regulation
R7529 T11550 T11549 themeOf induced,reduced
R7530 T11551 T11549 themeOf dependent,reduced
R7531 T11552 T11551 themeOf production,dependent
R7532 T11555 T11554 themeOf activation,involved
R12462 T18246 T18250 themeOf NFAT,binding
R12463 T18250 T18249 themeOf binding,crucial
R12863 T18777 T18779 themeOf Oct-1,binding
R13881 T20241 T20232 partOf promoter,IL-1RA
R13882 T20241 T20240 themeOf promoter,binding
R14746 T21390 T21412 themeOf NFAT,binding
R14747 T21391 T21412 themeOf NFIL-6,binding
R14748 T21405 T21413 themeOf TSST-1,binding
R14749 T21406 T21413 themeOf TSST-1,binding
R14750 T21407 T21413 themeOf TSST-1,binding
R14751 T21412 T21411 themeOf binding,led
R15307 T22318 T22333 themeOf p65,binding
R15308 T22319 T22333 themeOf p50,binding
R15309 T22325 T22334 themeOf p50,positive
R15310 T22326 T22334 themeOf p65,positive
R15311 T22327 T22334 themeOf NFATc1,positive
R15312 T22328 T22334 themeOf c2,positive
R15313 T22329 T22334 themeOf p65,positive
R15314 T22330 T22334 themeOf p50,positive
R15315 T22331 T22334 themeOf NFAT c2,positive
R15316 T22332 T22334 themeOf c1,positive
R15604 T22872 T22894 themeOf IL-1β,down-regulated
R15605 T22873 T22894 causeOf TSST-1,down-regulated
R15606 T22873 T22895 causeOf TSST-1,following
R15607 T22874 T22895 causeOf TSST-1,following
R15608 T22874 T22894 causeOf TSST-1,down-regulated
R15609 T22875 T22896 themeOf IL-1β,production
R15610 T22878 T22898 themeOf IL-1β,production
R15611 T22879 T22897 causeOf TSST-1,reduction
R15612 T22879 T22899 causeOf TSST-1,following
R15613 T22880 T22899 causeOf TSST-1,following
R15614 T22880 T22897 causeOf TSST-1,reduction
R15615 T22883 T22900 themeOf IL-1RA,following
R15616 T22884 T22900 causeOf TSST-1,following
R15617 T22885 T22900 causeOf TSST-1,following
R15618 T22886 T22901 themeOf IL-1RA,production
R15619 T22890 T22903 themeOf IL-1RA,production
R15620 T22891 T22902 causeOf TSST-1,higher
R15621 T22898 T22899 themeOf production,following
R15622 T22898 T22897 themeOf production,reduction
R15623 T22903 T22902 themeOf production,higher
R16242 T23852 T23858 causeOf TSST-1,induced
R16243 T23854 T23861 themeOf TSST-1,Binding
R16244 T23855 T23861 themeOf TSST-1,Binding
R16245 T23858 T23857 themeOf induced,modulated
R16246 T23859 T23858 themeOf binding,induced
R16446 T24152 T24164 causeOf TSST-1,induced
R16447 T24154 T24167 themeOf TSST-1,up-regulated
R16448 T24155 T24167 themeOf TSST-1,up-regulated
R16449 T24158 T24169 themeOf NFAT,binding
R16450 T24164 T24163 themeOf induced,modulated
R16451 T24165 T24163 themeOf binding,modulated
R16452 T24165 T24164 themeOf binding,induced
R16453 T24166 T24167 causeOf Binding,up-regulated
R16454 T24166 T24167 themeOf Binding,up-regulated
R16455 T24169 T24168 themeOf binding,elevated
R16857 T24756 T24773 causeOf TSST-1,following
R16858 T24756 T24772 causeOf TSST-1,Decreased
R16859 T24757 T24773 causeOf TSST-1,following
R16860 T24757 T24772 causeOf TSST-1,Decreased
R16861 T24760 T24774 causeOf TSST-1,following
R16862 T24761 T24774 causeOf TSST-1,following
R16863 T24762 T24774 causeOf TSST-1,following
R16864 T24770 T24777 themeOf IL-1RA,production
R16865 T24771 T24777 themeOf IL-1β,production
R16866 T24777 T24776 themeOf production,higher
R17237 T25443 T25455 themeOf NFAT,binding
R17238 T25444 T25455 themeOf NFIL-6,binding
R17239 T25448 T25461 themeOf IL-1RA,decreased
R17240 T25451 T25463 causeOf NFIL-6,reduced
R17241 T25452 T25464 themeOf IL-1RA,production
R17242 T25454 T25453 themeOf induced,Inhibition
R17243 T25455 T25454 themeOf binding,induced
R17244 T25456 T25455 themeOf promoter,binding
R17245 T25456 T25445 partOf promoter,IL-1RA
R17246 T25459 T25458 themeOf binding,decrease
R17247 T25461 T25460 themeOf decreased,resulted
R17248 T25464 T25465 themeOf production,following
R17249 T25464 T25463 themeOf production,reduced
R1842 T3036 T3065 themeOf NFIL-6,Binding
R1843 T3037 T3065 themeOf NFAT,Binding
R1844 T3039 T3065 themeOf IL-6,Binding
R1845 T3041 T3067 causeOf TSST-1,following
R1846 T3042 T3067 causeOf TSST-1,following
R1847 T3043 T3068 themeOf NFIL-6,binding
R1848 T3047 T3069 causeOf TSST-1,induced
R1849 T3049 T3071 themeOf p65,binding
R1850 T3050 T3071 themeOf p50,binding
R1851 T3051 T3072 themeOf p65,binding
R1852 T3055 T3077 causeOf TSST-1,induced
R1853 T3056 T3078 themeOf TSST-1,binding
R1854 T3060 T3080 themeOf NFAT,binding
R1855 T3063 T3083 themeOf NFATc2,binding
R1856 T3064 T3083 themeOf NFATc1,binding
R1857 T3066 T3040 partOf promoters,IFNγ
R1858 T3066 T3065 themeOf promoters,Binding
R1859 T3066 T3038 partOf promoters,TNFα
R1860 T3071 T3070 themeOf binding,induced
R1861 T3074 T3073 themeOf induced,change
R1862 T3075 T3074 themeOf binding,induced
R1863 T3077 T3076 themeOf induced,decreased
R1864 T3078 T3077 themeOf binding,induced
R1865 T3078 T3076 themeOf binding,decreased
R1866 T3081 T3080 themeOf promoter,binding
R1867 T3081 T3061 partOf promoter,IFNγ
R1868 T3083 T3082 themeOf binding,induced
R2716 T4414 T4484 themeOf TNFα,production
R2717 T4415 T4484 themeOf IL-8,production
R2718 T4416 T4484 themeOf IL-6,production
R2719 T4417 T4484 themeOf IFNγ,production
R2720 T4420 T4485 themeOf IL-1β,production
R2721 T4421 T4488 themeOf IL-1β,production
R2722 T4423 T4489 themeOf IL-1β,reduction
R2723 T4424 T4489 causeOf TSST-1,reduction
R2724 T4426 T4491 causeOf TSST-1,induced
R2725 T4427 T4491 themeOf IL-1β,induced
R2726 T4430 T4495 themeOf IL-6,production
R2727 T4431 T4497 themeOf IL-6,production
R2728 T4432 T4496 causeOf TSST-1,decreased
R2729 T4433 T4496 causeOf TSST-1,decreased
R2730 T4436 T4500 themeOf IL-8,production
R2731 T4437 T4503 themeOf IL-8,production
R2732 T4438 T4505 themeOf IL-8,production
R2733 T4439 T4506 causeOf TSST-1,following
R2734 T4439 T4504 causeOf TSST-1,alteration
R2735 T4440 T4506 causeOf TSST-1,following
R2736 T4440 T4504 causeOf TSST-1,alteration
R2737 T4441 T4506 causeOf TSST-1,following
R2738 T4441 T4504 causeOf TSST-1,alteration
R2739 T4443 T4507 themeOf IL-8,produced
R2740 T4444 T4507 themeOf IL-1RA,produced
R2741 T4445 T4509 themeOf IL-1RA,production
R2742 T4446 T4510 causeOf TSST-1,increase
R2743 T4447 T4511 themeOf IL-1RA,production
R2744 T4450 T4513 causeOf TSST-1,induced
R2745 T4451 T4513 themeOf IL-1RA,induced
R2746 T4452 T4515 themeOf IL-8,productions
R2747 T4453 T4515 themeOf IL-1RA,productions
R2748 T4457 T4517 themeOf IL-1RA,induced
R2749 T4460 T4519 themeOf TNFα,production
R2750 T4465 T4521 themeOf IFNγ,production
R2751 T4466 T4524 themeOf IFNγ,production
R2752 T4467 T4525 causeOf TSST-1,following
R2753 T4467 T4526 causeOf TSST-1,down-regulation
R2754 T4468 T4525 causeOf TSST-1,following
R2755 T4468 T4526 causeOf TSST-1,down-regulation
R2756 T4468 T4523 causeOf TSST-1,increase
R2757 T4469 T4526 causeOf TSST-1,down-regulation
R2758 T4475 T4527 themeOf IL-2,production
R2759 T4476 T4528 themeOf IL-12,induced
R2760 T4476 T4527 themeOf IL-12,production
R2761 T4477 T4528 themeOf IL-4,induced
R2762 T4477 T4527 themeOf IL-4,production
R2763 T4478 T4528 themeOf IL-10,induced
R2764 T4478 T4527 themeOf IL-10,production
R2765 T4479 T4528 themeOf TGFβ 1,induced
R2766 T4479 T4527 themeOf TGFβ 1,production
R2767 T4484 T4483 themeOf production,lead
R2768 T4485 T4486 themeOf production,following
R2769 T4488 T4487 themeOf production,up-regulation
R2770 T4491 T4490 themeOf induced,reduction
R2771 T4494 T4493 themeOf induced,alteration
R2772 T4495 T4494 themeOf production,induced
R2773 T4497 T4496 themeOf production,decreased
R2774 T4499 T4498 themeOf substantial,induced
R2775 T4500 T4499 themeOf production,substantial
R2776 T4502 T4501 themeOf increase,resulted
R2777 T4503 T4502 themeOf production,increase
R2778 T4505 T4504 themeOf production,alteration
R2779 T4505 T4506 themeOf production,following
R2780 T4509 T4508 themeOf production,alter
R2781 T4511 T4510 themeOf production,increase
R2782 T4513 T4512 themeOf induced,elevated
R2783 T4515 T4514 themeOf productions,induced
R2784 T4519 T4518 themeOf production,change
R2785 T4521 T4522 themeOf production,following
R2786 T4523 T4525 themeOf increase,following
R2787 T4523 T4526 themeOf increase,down-regulation
R2788 T4524 T4526 themeOf production,down-regulation
R2789 T4524 T4523 themeOf production,increase
R2790 T4524 T4525 themeOf production,following
R2791 T4527 T4528 themeOf production,induced
R5057 T7904 T7925 themeOf NFIL-6,binding
R5058 T7905 T7925 themeOf NFAT,binding
R5059 T7907 T7926 causeOf TSST-1,induced
R5060 T7908 T7927 themeOf IL-1RA,expression
R5061 T7909 T7928 themeOf TNFα,bind
R5062 T7910 T7928 themeOf IL-6,bind
R5063 T7914 T7930 causeOf TSST-1,increased
R5064 T7915 T7932 themeOf TSST-1,binding
R5065 T7916 T7932 themeOf TSST-1,binding
R5066 T7919 T7935 causeOf TSST-1,induced
R5067 T7920 T7940 causeOf TSST-1,induced
R5068 T7921 T7942 themeOf TSST-1,binding
R5069 T7922 T7947 themeOf TSST-1,binding
R5070 T7925 T7924 themeOf binding,Role
R5071 T7927 T7926 themeOf expression,induced
R5072 T7931 T7930 themeOf binding,increased
R5073 T7932 T7930 causeOf binding,increased
R5074 T7933 T7934 themeOf Binding,elevated
R5075 T7936 T7935 themeOf binding,induced
R5076 T7936 T7938 themeOf binding,down-regulated
R5077 T7942 T7941 themeOf binding,increased
R5078 T7947 T7949 themeOf binding,elevated
R5079 T7948 T7947 themeOf site,binding
R6252 T9473 T9495 causeOf TSST-1,induced
R6253 T9473 T9494 causeOf TSST-1,modulated
R6254 T9474 T9495 themeOf IL-1β,induced
R6255 T9475 T9495 themeOf IL-1RA,induced
R6256 T9487 T9498 themeOf IL-1RA,production
R6257 T9488 T9498 themeOf IL-1β,production
R6258 T9489 T9499 themeOf IL-1,decrease
R6259 T9490 T9501 themeOf IL-2,release
R6260 T9491 T9501 causeOf TSST-1,release
R6261 T9491 T9502 causeOf TSST-1,following
R6262 T9492 T9502 causeOf TSST-1,following
R6263 T9493 T9502 causeOf TSST-1,following
R6264 T9495 T9494 themeOf induced,modulated
R6265 T9498 T9497 themeOf production,higher
R6266 T9501 T9500 themeOf release,dependent
R6267 T9501 T9502 themeOf release,following
R6805 T10370 T10382 themeOf IL-1RA,induction
R6806 T10372 T10383 causeOf NFIL-6,via
R6807 T10374 T10388 themeOf IL-1RA,reduction
R6808 T10377 T10391 themeOf IL-1RA,decrease
R6809 T10379 T10395 themeOf IL-1RA,release
R6810 T10386 T10385 themeOf binding,down-regulated
R6811 T10390 T10389 themeOf binding,reduction
R6812 T10394 T10393 themeOf decreased,led
R6813 T10395 T10394 themeOf release,decreased
R4 T45 T71 themeOf tumor necrosis factor α,production
R39 T94 T95 themeOf regulation,modulated

test3

Id Subject Object Predicate Lexical cue
T100 602-608 Protein denotes TSST-1
T101 668-687 Protein denotes NFinterleukin(IL)-6
T102 692-696 Protein denotes NFAT
T103 715-721 Protein denotes TSST-1
T104 764-769 Protein denotes IL-1β
T96 69-73 Protein denotes IL-6
T97 119-124 Protein denotes IL-1β
T98 125-149 Protein denotes IL-1 receptor antagonist
T99 572-600 Protein denotes toxic shock syndrome toxin 1
T105 771-775 Protein denotes IL-6
T106 777-800 Protein denotes tumor necrosis factor α
T107 804-816 Protein denotes interferon γ
T108 914-918 Protein denotes IL-8
T109 1004-1008 Protein denotes IL-8
T110 1034-1057 Protein denotes IL-1receptor antagonist
T111 1058-1060 Protein denotes RA
T112 1162-1166 Protein denotes IL-8
T113 1274-1280 Protein denotes IL-1RA
T114 1385-1391 Protein denotes TSST-1
T115 1477-1483 Protein denotes TSST-1
T116 1513-1519 Protein denotes NFIL-6
T117 1524-1528 Protein denotes NFAT
T118 1567-1573 Protein denotes IL-1RA
T119 1615-1621 Protein denotes TSST-1
T120 1669-1674 Protein denotes IL-1β
T121 1679-1683 Protein denotes IL-6
T122 1732-1738 Protein denotes TSST-1
T123 1747-1752 Protein denotes IL-1β
T124 1753-1759 Protein denotes IL-1RA
T125 1851-1857 Protein denotes TSST-1
T126 1867-1871 Protein denotes IL-1
T127 1896-1900 Protein denotes IL-2
T128 2102-2108 Protein denotes IL-1RA
T129 2199-2205 Protein denotes IL-1RA
T130 31-38 Binding denotes binding
T131 69-73 Protein denotes IL-6
T132 74-81 Positive_regulation denotes leading
T133 119-124 Protein denotes IL-1β
T134 125-149 Protein denotes IL-1 receptor antagonist
T135 572-600 Protein denotes toxic shock syndrome toxin 1
T136 602-608 Protein denotes TSST-1
T137 631-641 Positive_regulation denotes activation
T138 668-687 Protein denotes NFinterleukin(IL)-6
T139 692-696 Protein denotes NFAT
T140 715-721 Protein denotes TSST-1
T141 750-760 Gene_expression denotes production
T142 764-769 Protein denotes IL-1β
T143 771-775 Protein denotes IL-6
T144 777-800 Protein denotes tumor necrosis factor α
T145 804-816 Protein denotes interferon γ
T146 817-824 Positive_regulation denotes induced
T147 882-889 Positive_regulation denotes induced
T148 914-918 Protein denotes IL-8
T149 961-968 Binding denotes binding
T150 1004-1008 Protein denotes IL-8
T151 1022-1030 Positive_regulation denotes increase
T152 1034-1057 Protein denotes IL-1receptor antagonist
T153 1058-1060 Protein denotes RA
T154 1062-1072 Gene_expression denotes production
T155 1162-1166 Protein denotes IL-8
T156 1192-1199 Positive_regulation denotes induced
T157 1212-1219 Binding denotes binding
T158 1274-1280 Protein denotes IL-1RA
T159 1385-1391 Protein denotes TSST-1
T160 1451-1459 Positive_regulation denotes elevated
T161 1477-1483 Protein denotes TSST-1
T162 1484-1491 Positive_regulation denotes induced
T163 1496-1503 Binding denotes binding
T164 1513-1519 Protein denotes NFIL-6
T165 1524-1528 Protein denotes NFAT
T166 1555-1563 Positive_regulation denotes increase
T167 1567-1573 Protein denotes IL-1RA
T168 1615-1621 Protein denotes TSST-1
T169 1622-1629 Positive_regulation denotes induced
T170 1656-1665 Negative_regulation denotes reduction
T171 1669-1674 Protein denotes IL-1β
T172 1679-1683 Protein denotes IL-6
T173 1732-1738 Protein denotes TSST-1
T174 1739-1746 Positive_regulation denotes induced
T175 1747-1752 Protein denotes IL-1β
T176 1753-1759 Protein denotes IL-1RA
T177 1837-1846 Negative_regulation denotes decreased
T178 1851-1857 Protein denotes TSST-1
T179 1858-1865 Positive_regulation denotes induced
T180 1867-1871 Protein denotes IL-1
T181 1872-1881 Positive_regulation denotes dependent
T182 1882-1892 Gene_expression denotes production
T183 1896-1900 Protein denotes IL-2
T184 2102-2108 Protein denotes IL-1RA
T185 2181-2191 Regulation denotes regulation
T186 2199-2205 Protein denotes IL-1RA
T26183 27870-27876 Protein denotes IL-1RA
T26182 27870-27876 Protein denotes IL-1RA
T25499 23596-23605 Positive_regulation denotes following
T25498 23575-23581 Protein denotes IL-1RA
T25497 23561-23571 Gene_expression denotes production
T25496 23549-23556 Negative_regulation denotes reduced
T25495 23528-23534 Protein denotes NFIL-6
T25494 23519-23523 Protein denotes NFAT
T25493 23499-23509 Negative_regulation denotes Inhibition
T25492 23429-23434 Protein denotes GAPDH
T25491 23386-23395 Positive_regulation denotes following
T25490 23374-23380 Protein denotes IL-1RA
T25489 23364-23373 Negative_regulation denotes decreased
T25488 23352-23360 Positive_regulation denotes resulted
T25487 23345-23351 Protein denotes NFIL-6
T25486 23336-23340 Protein denotes NFAT
T25485 23316-23326 Negative_regulation denotes Inhibition
T25484 23197-23204 Binding denotes binding
T25483 23185-23193 Negative_regulation denotes decrease
T25482 22889-22897 Entity denotes promoter
T25481 22882-22888 Protein denotes IL-1RA
T25480 22867-22874 Binding denotes binding
T25479 22856-22862 Protein denotes NFIL-6
T25478 22847-22851 Protein denotes NFAT
T25477 22833-22840 Positive_regulation denotes induced
T25476 22816-22826 Negative_regulation denotes Inhibition
T25475 23575-23581 Protein denotes IL-1RA
T25474 23528-23534 Protein denotes NFIL-6
T25473 23519-23523 Protein denotes NFAT
T25472 23429-23434 Protein denotes GAPDH
T25471 23374-23380 Protein denotes IL-1RA
T25470 23345-23351 Protein denotes NFIL-6
T25469 23336-23340 Protein denotes NFAT
T25468 22882-22888 Protein denotes IL-1RA
T25467 22856-22862 Protein denotes NFIL-6
T25466 22847-22851 Protein denotes NFAT
T24785 21014-21020 Protein denotes TSST-1
T24784 20977-20983 Protein denotes TSST-1
T24783 20919-20925 Protein denotes IL-1RA
T24782 20913-20918 Protein denotes IL-1β
T24781 20879-20885 Protein denotes TSST-1
T24780 20855-20861 Protein denotes TSST-1
T24779 20827-20833 Protein denotes IL-1RA
T24778 20821-20826 Protein denotes IL-1β
T24818 21479-21484 Protein denotes IL-1β
T24817 21464-21470 Protein denotes IL-1RA
T24816 21450-21460 Gene_expression denotes production
T24815 21443-21449 Positive_regulation denotes higher
T24814 21300-21306 Protein denotes TSST-1
T24813 21279-21285 Protein denotes TSST-1
T24812 21266-21272 Protein denotes TSST-1
T24811 21226-21232 Protein denotes IL-1RA
T24810 21220-21225 Protein denotes IL-1β
T24809 21107-21113 Protein denotes IL-1RA
T24808 21096-21101 Protein denotes IL-1β
T24807 21068-21076 Positive_regulation denotes resulted
T24806 21027-21033 Protein denotes TSST-1
T24805 21014-21020 Protein denotes TSST-1
T24804 20977-20983 Protein denotes TSST-1
T24803 20919-20925 Protein denotes IL-1RA
T24802 20913-20918 Protein denotes IL-1β
T24801 20879-20885 Protein denotes TSST-1
T24800 20855-20861 Protein denotes TSST-1
T24799 20840-20849 Positive_regulation denotes following
T24798 20827-20833 Protein denotes IL-1RA
T24797 20821-20826 Protein denotes IL-1β
T24796 20811-20820 Negative_regulation denotes Decreased
T24795 21479-21484 Protein denotes IL-1β
T24794 21464-21470 Protein denotes IL-1RA
T24793 21300-21306 Protein denotes TSST-1
T24792 21279-21285 Protein denotes TSST-1
T24791 21266-21272 Protein denotes TSST-1
T24790 21226-21232 Protein denotes IL-1RA
T24789 21220-21225 Protein denotes IL-1β
T24788 21107-21113 Protein denotes IL-1RA
T24787 21096-21101 Protein denotes IL-1β
T24786 21027-21033 Protein denotes TSST-1
T24195 19648-19654 Protein denotes TSST-1
T24194 19609-19615 Protein denotes TSST-1
T24193 19379-19385 Protein denotes TSST-1
T24192 19300-19306 Protein denotes IL-1RA
T24191 19264-19271 Binding denotes binding
T24190 19255-19259 Protein denotes NFAT
T24189 19177-19183 Protein denotes TSST-1
T24188 19160-19166 Protein denotes TSST-1
T24187 19085-19091 Protein denotes TSST-1
T24186 19017-19023 Protein denotes TSST-1
T24185 18982-18984 Positive_regulation denotes up
T24184 18970-18977 Binding denotes Binding
T24183 18953-18959 Protein denotes IL-1RA
T24182 18915-18922 Binding denotes binding
T24181 18896-18902 Protein denotes TSST-1
T24180 19648-19654 Protein denotes TSST-1
T24179 19609-19615 Protein denotes TSST-1
T24178 19379-19385 Protein denotes TSST-1
T24177 19300-19306 Protein denotes IL-1RA
T24176 19255-19259 Protein denotes NFAT
T24175 19177-19183 Protein denotes TSST-1
T24174 19160-19166 Protein denotes TSST-1
T24173 19085-19091 Protein denotes TSST-1
T24172 19017-19023 Protein denotes TSST-1
T24171 18953-18959 Protein denotes IL-1RA
T24170 18896-18902 Protein denotes TSST-1
T23875 18829-18836 Binding denotes binding
T23874 18710-18716 Protein denotes TSST-1
T23873 18679-18685 Protein denotes TSST-1
T23872 18649-18655 Protein denotes TSST-1
T23871 18606-18613 Binding denotes Binding
T23870 18589-18595 Protein denotes IL-1RA
T23869 18554-18561 Binding denotes binding
T23868 18546-18553 Positive_regulation denotes induced
T23867 18539-18545 Protein denotes TSST-1
T23866 18710-18716 Protein denotes TSST-1
T23865 18679-18685 Protein denotes TSST-1
T23864 18649-18655 Protein denotes TSST-1
T23863 18589-18595 Protein denotes IL-1RA
T23862 18539-18545 Protein denotes TSST-1
T22942 12652-12657 Protein denotes IL-1β
T22941 12623-12629 Protein denotes TSST-1
T22940 12536-12542 Protein denotes TSST-1
T22939 12512-12518 Protein denotes TSST-1
T22938 12497-12506 Positive_regulation denotes following
T22937 12486-12496 Gene_expression denotes production
T22936 12480-12485 Protein denotes IL-1β
T22935 12467-12476 Negative_regulation denotes reduction
T22934 12398-12404 Protein denotes TSST-1
T22933 12385-12391 Protein denotes TSST-1
T22932 12303-12313 Gene_expression denotes production
T22931 12297-12302 Protein denotes IL-1β
T22930 12267-12273 Protein denotes TSST-1
T22929 12243-12249 Protein denotes TSST-1
T22928 12228-12237 Positive_regulation denotes following
T22927 12199-12213 Negative_regulation denotes down-regulated
T22926 12189-12194 Protein denotes IL-1β
T22925 13297-13303 Protein denotes IL-1RA
T22924 13270-13276 Protein denotes TSST-1
T22923 13176-13182 Protein denotes TSST-1
T22922 13104-13110 Protein denotes IL-1RA
T22921 13054-13060 Protein denotes TSST-1
T22920 12956-12962 Protein denotes TSST-1
T22919 12943-12949 Protein denotes TSST-1
T22918 12854-12860 Protein denotes IL-1RA
T22917 12824-12830 Protein denotes TSST-1
T22916 12786-12792 Protein denotes TSST-1
T22915 12748-12754 Protein denotes IL-1RA
T22914 12652-12657 Protein denotes IL-1β
T22913 12623-12629 Protein denotes TSST-1
T22912 12536-12542 Protein denotes TSST-1
T22911 12512-12518 Protein denotes TSST-1
T22910 12480-12485 Protein denotes IL-1β
T22909 12398-12404 Protein denotes TSST-1
T22908 12385-12391 Protein denotes TSST-1
T22907 12297-12302 Protein denotes IL-1β
T22906 12267-12273 Protein denotes TSST-1
T22905 12243-12249 Protein denotes TSST-1
T22904 12189-12194 Protein denotes IL-1β
T22956 13297-13303 Protein denotes IL-1RA
T22955 13270-13276 Protein denotes TSST-1
T22954 13176-13182 Protein denotes TSST-1
T22953 13111-13121 Gene_expression denotes production
T22952 13104-13110 Protein denotes IL-1RA
T22951 13054-13060 Protein denotes TSST-1
T22950 12956-12962 Protein denotes TSST-1
T22949 12943-12949 Protein denotes TSST-1
T22948 12861-12871 Gene_expression denotes production
T22947 12854-12860 Protein denotes IL-1RA
T22946 12824-12830 Protein denotes TSST-1
T22945 12786-12792 Protein denotes TSST-1
T22944 12771-12780 Positive_regulation denotes following
T22943 12748-12754 Protein denotes IL-1RA
T22367 10740-10742 Protein denotes c1
T22366 10731-10738 Protein denotes NFAT c2
T22365 10723-10726 Protein denotes p50
T22364 10718-10721 Protein denotes p65
T22363 10700-10708 Gene_expression denotes positive
T22362 10624-10626 Protein denotes c2
T22361 10616-10622 Protein denotes NFATc1
T22360 10604-10607 Protein denotes p65
T22359 10599-10602 Protein denotes p50
T22358 10581-10589 Gene_expression denotes positive
T22357 10529-10534 Protein denotes c-rel
T22356 10524-10527 Protein denotes p52
T22355 10379-10383 Protein denotes NFAT
T22354 10274-10281 Binding denotes binding
T22353 10239-10241 Protein denotes c1
T22352 10232-10238 Protein denotes NFATc2
T22351 10224-10227 Protein denotes p50
T22350 10220-10223 Protein denotes p65
T22349 10740-10742 Protein denotes c1
T22348 10731-10738 Protein denotes NFAT c2
T22347 10723-10726 Protein denotes p50
T22346 10718-10721 Protein denotes p65
T22345 10624-10626 Protein denotes c2
T22344 10616-10622 Protein denotes NFATc1
T22343 10604-10607 Protein denotes p65
T22342 10599-10602 Protein denotes p50
T22341 10529-10534 Protein denotes c-rel
T22340 10524-10527 Protein denotes p52
T22339 10379-10383 Protein denotes NFAT
T22338 10239-10241 Protein denotes c1
T22337 10232-10238 Protein denotes NFATc2
T22336 10224-10227 Protein denotes p50
T22335 10220-10223 Protein denotes p65
T20980 40720-40726 Protein denotes TSST-1
T20979 40707-40713 Protein denotes TSST-1
T20978 40435-40441 Protein denotes TSST-1
T20977 40422-40428 Protein denotes TSST-1
T20976 40720-40726 Protein denotes TSST-1
T20975 40707-40713 Protein denotes TSST-1
T20974 40435-40441 Protein denotes TSST-1
T20973 40422-40428 Protein denotes TSST-1
T21444 9241-9245 Protein denotes IL-8
T21443 9232-9236 Protein denotes IL-6
T21442 9226-9230 Protein denotes TNFα
T21441 9220-9224 Protein denotes IFNγ
T21440 9172-9176 Protein denotes IL-8
T21439 9157-9163 Protein denotes NFIL-6
T21438 9145-9149 Protein denotes NFAT
T21437 9002-9008 Protein denotes NFIL-6
T21436 8987-8991 Protein denotes NFAT
T21435 8976-8983 Binding denotes binding
T21434 9947-9953 Protein denotes TSST-1
T21433 9765-9771 Protein denotes TSST-1
T21432 9739-9745 Protein denotes TSST-1
T21431 9676-9682 Protein denotes TSST-1
T21430 9661-9667 Protein denotes TSST-1
T21429 9641-9647 Protein denotes TSST-1
T21428 9506-9509 Protein denotes p50
T21427 9497-9500 Protein denotes p65
T21426 9483-9487 Protein denotes IL-8
T21425 9375-9379 Protein denotes IL-8
T21424 9356-9362 Protein denotes NFIL-6
T21423 9336-9340 Protein denotes NFAT
T21422 9241-9245 Protein denotes IL-8
T21421 9232-9236 Protein denotes IL-6
T21420 9226-9230 Protein denotes TNFα
T21419 9220-9224 Protein denotes IFNγ
T21418 9172-9176 Protein denotes IL-8
T21417 9157-9163 Protein denotes NFIL-6
T21416 9145-9149 Protein denotes NFAT
T21415 9002-9008 Protein denotes NFIL-6
T21414 8987-8991 Protein denotes NFAT
T21458 9947-9953 Protein denotes TSST-1
T21457 9765-9771 Protein denotes TSST-1
T21456 9739-9745 Protein denotes TSST-1
T21455 9676-9682 Protein denotes TSST-1
T21454 9661-9667 Protein denotes TSST-1
T21453 9641-9647 Protein denotes TSST-1
T21452 9626-9635 Positive_regulation denotes following
T21451 9610-9617 Binding denotes binding
T21450 9506-9509 Protein denotes p50
T21449 9497-9500 Protein denotes p65
T21448 9483-9487 Protein denotes IL-8
T21447 9375-9379 Protein denotes IL-8
T21446 9356-9362 Protein denotes NFIL-6
T21445 9336-9340 Protein denotes NFAT
T20260 39932-39938 Protein denotes IL-1RA
T20259 39688-39699 Transcription denotes transcripts
T20258 39682-39687 Protein denotes GAPDH
T20257 39671-39677 Protein denotes IL-1RA
T20256 39489-39495 Protein denotes IL-1RA
T20255 39420-39421 Protein denotes 3
T20254 39413-39419 Protein denotes NFATP2
T20253 39360-39366 Protein denotes NFIL-6
T20252 38870-38876 Protein denotes IL-1RA
T20251 38830-38837 Binding denotes binding
T20250 38804-38811 Negative_regulation denotes inhibit
T20249 39932-39938 Protein denotes IL-1RA
T20248 39682-39687 Protein denotes GAPDH
T20247 39671-39677 Protein denotes IL-1RA
T20246 39489-39495 Protein denotes IL-1RA
T20245 39420-39421 Protein denotes 3
T20244 39413-39419 Protein denotes NFATP2
T20243 39360-39366 Protein denotes NFIL-6
T20242 38870-38876 Protein denotes IL-1RA
T19742 38342-38346 Protein denotes IL-1
T19741 38298-38302 Protein denotes IL-2
T19740 38228-38234 Protein denotes TGFβ 1
T19739 38156-38160 Protein denotes IL-8
T19738 38145-38151 Protein denotes IL-1RA
T19737 38070-38074 Protein denotes IL-6
T19736 38061-38065 Protein denotes IL-1
T19735 38055-38059 Protein denotes TNFα
T19734 38049-38053 Protein denotes IFNγ
T19733 38342-38346 Protein denotes IL-1
T19732 38298-38302 Protein denotes IL-2
T19731 38228-38234 Protein denotes TGFβ 1
T19730 38156-38160 Protein denotes IL-8
T19729 38145-38151 Protein denotes IL-1RA
T19728 38070-38074 Protein denotes IL-6
T19727 38061-38065 Protein denotes IL-1
T19726 38055-38059 Protein denotes TNFα
T19725 38049-38053 Protein denotes IFNγ
T19194 37240-37246 Protein denotes NFATc1
T19193 37212-37218 Protein denotes NFATc2
T19192 37186-37191 Protein denotes c-rel
T19191 37127-37130 Protein denotes p52
T19190 37101-37104 Protein denotes p65
T19189 37073-37076 Protein denotes p50
T19188 36967-36972 Protein denotes c-Rel
T19187 36944-36947 Protein denotes p52
T19186 36686-36690 Protein denotes NFAT
T18787 36587-36594 Binding denotes binding
T18786 36506-36511 Protein denotes Oct-1
T18785 36400-36402 Protein denotes 50
T18784 36396-36399 Protein denotes p65
T18783 36201-36208 Binding denotes binding
T18782 36506-36511 Protein denotes Oct-1
T18781 36400-36402 Protein denotes 50
T18780 36396-36399 Protein denotes p65
T18260 34880-34884 Protein denotes IFNγ
T18259 34874-34878 Protein denotes IL-8
T18258 34868-34872 Protein denotes TNFα
T18257 35528-35532 Protein denotes NFAT
T18256 35417-35421 Protein denotes TNFα
T18255 35359-35363 Protein denotes IFNγ
T18254 34889-34893 Protein denotes IL-6
T18253 34880-34884 Protein denotes IFNγ
T18252 34874-34878 Protein denotes IL-8
T18251 34868-34872 Protein denotes TNFα
T17938 34702-34708 Protein denotes TSST-1
T17937 34454-34460 Protein denotes TSST-1
T17936 34702-34708 Protein denotes TSST-1
T17935 34454-34460 Protein denotes TSST-1
T18266 35528-35532 Protein denotes NFAT
T18265 35517-35524 Binding denotes binding
T18264 35501-35508 Positive_regulation denotes crucial
T18263 35417-35421 Protein denotes TNFα
T18262 35359-35363 Protein denotes IFNγ
T18261 34889-34893 Protein denotes IL-6
T17460 33002-33016 Phosphorylation denotes phosphorylated
T17104 32946-32952 Protein denotes IL-1RA
T17103 32940-32945 Protein denotes IL-1β
T17102 32654-32660 Protein denotes IL-1RA
T17101 32595-32602 Binding denotes binding
T17100 32457-32463 Protein denotes IL-1RA
T17099 32427-32433 Protein denotes TSST-1
T17098 32377-32383 Protein denotes TSST-1
T17097 32946-32952 Protein denotes IL-1RA
T17096 32940-32945 Protein denotes IL-1β
T17095 32654-32660 Protein denotes IL-1RA
T17094 32457-32463 Protein denotes IL-1RA
T17093 32427-32433 Protein denotes TSST-1
T17092 32377-32383 Protein denotes TSST-1
T11850 32024-32030 Protein denotes IL-1RA
T11849 32010-32019 Positive_regulation denotes activated
T11848 31698-31702 Protein denotes NFAT
T11847 31608-31618 Gene_expression denotes production
T11846 31602-31607 Protein denotes IL-1β
T11845 31589-31593 Protein denotes -1RA
T11844 31577-31585 Regulation denotes controls
T11843 31362-31368 Protein denotes TSST-1
T11842 31346-31352 Protein denotes TSST-1
T11841 31100-31110 Gene_expression denotes production
T11840 31095-31099 Protein denotes IL-2
T11839 31085-31094 Regulation denotes dependent
T11838 31080-31084 Protein denotes IL-1
T11837 31071-31078 Positive_regulation denotes induced
T11836 31064-31070 Protein denotes TSST-1
T11835 31052-31059 Negative_regulation denotes reduced
T11834 31014-31025 Negative_regulation denotes inactivated
T11833 30993-30998 Protein denotes IL-1β
T11832 30965-30977 Negative_regulation denotes unreasonable
T11831 30919-30925 Protein denotes TSST-1
T11830 30904-30913 Positive_regulation denotes following
T11829 30891-30897 Protein denotes IL-1RA
T11828 30885-30890 Protein denotes IL-1β
T11827 30851-30855 Protein denotes IL-1
T11826 30840-30847 Regulation denotes effects
T11825 30817-30824 Regulation denotes control
T11824 30805-30810 Protein denotes IL-1β
T11823 30793-30799 Protein denotes IL-1RA
T11822 30702-30708 Protein denotes TSST-1
T11821 30687-30696 Positive_regulation denotes following
T11820 30674-30680 Protein denotes IL-1RA
T11819 30668-30673 Protein denotes IL-1β
T11818 30652-30660 Negative_regulation denotes decrease
T11817 30559-30569 Gene_expression denotes production
T11816 30552-30558 Protein denotes IL-1RA
T11815 30544-30551 Positive_regulation denotes induced
T11814 30537-30543 Protein denotes TSST-1
T11813 30516-30529 Positive_regulation denotes up-regulation
T11812 30379-30386 Binding denotes binding
T11811 30371-30378 Positive_regulation denotes induced
T11810 30364-30370 Protein denotes TSST-1
T11809 30352-30360 Positive_regulation denotes increase
T11808 30173-30180 Binding denotes binding
T11807 30158-30164 Protein denotes TSST-1
T11806 29948-29954 Protein denotes IL-1RA
T11805 29647-29653 Protein denotes IL-1RA
T11804 29634-29638 Protein denotes TNFα
T11803 29432-29438 Protein denotes IL-1RA
T11802 29377-29390 Positive_regulation denotes up-regulation
T11801 29349-29353 Protein denotes TNFα
T11800 29325-29332 Binding denotes binding
T11799 29312-29319 Positive_regulation denotes induced
T11798 29305-29311 Protein denotes TSST-1
T11797 29269-29284 Negative_regulation denotes down-regulation
T11796 29216-29225 Positive_regulation denotes increased
T11795 29164-29171 Binding denotes binding
T11794 29156-29163 Positive_regulation denotes induced
T11793 29149-29155 Protein denotes TSST-1
T11792 29120-29127 Binding denotes binding
T11791 29112-29119 Positive_regulation denotes induced
T11790 29096-29102 Protein denotes TSST-1
T11773 28713-28717 Protein denotes IL-8
T11772 28660-28664 Protein denotes NFAT
T11771 28649-28655 Protein denotes NFIL-6
T11770 28632-28639 Binding denotes binding
T11769 28624-28631 Positive_regulation denotes induced
T11768 28617-28623 Protein denotes TSST-1
T11767 28576-28582 Positive_regulation denotes caused
T11766 28540-28546 Protein denotes IL-1RA
T11765 28523-28536 Positive_regulation denotes up-regulation
T11764 28476-28480 Protein denotes IL-6
T11763 28466-28471 Protein denotes IL-1β
T11762 28447-28462 Negative_regulation denotes down-regulation
T11761 28386-28392 Protein denotes IL-1RA
T11760 28380-28385 Protein denotes IL-1β
T11759 28372-28379 Positive_regulation denotes induced
T11758 28365-28371 Protein denotes TSST-1
T11757 28353-28360 Regulation denotes altered
T11756 28201-28207 Protein denotes TSST-1
T11755 27682-27688 Protein denotes IL-1RA
T11754 27651-27655 Protein denotes IL-8
T11753 27640-27650 Positive_regulation denotes attracting
T11752 27612-27621 Positive_regulation denotes induction
T11751 27548-27576 Protein denotes p38 mitogen-activated kinase
T11750 27512-27516 Protein denotes TNFα
T11749 27503-27507 Protein denotes IFNγ
T11748 27485-27492 Localization denotes release
T11747 27408-27415 Binding denotes binding
T11746 27388-27394 Protein denotes TSST-1
T11745 27347-27351 Protein denotes TNFα
T11744 27222-27242 Protein denotes Toll-like receptor 4
T11743 27161-27167 Protein denotes TSST-1
T11742 27076-27082 Protein denotes TSST-1
T11741 26956-26964 Positive_regulation denotes response
T11740 26946-26952 Protein denotes IL-1RA
T11739 26933-26937 Protein denotes IL-8
T11738 26925-26932 Gene_expression denotes produce
T11737 26822-26828 Protein denotes IL-1RA
T11736 26814-26821 Gene_expression denotes produce
T11735 26708-26714 Protein denotes IL-1RA
T11734 26695-26704 Positive_regulation denotes induction
T11733 26681-26690 Positive_regulation denotes necessary
T11732 26567-26574 Positive_regulation denotes induced
T11731 26543-26549 Protein denotes IL-1RA
T11730 26513-26519 Protein denotes IL-1RA
T11729 26489-26496 Binding denotes binding
T11728 26482-26488 Protein denotes NFIL-6
T11727 26473-26477 Protein denotes NFAT
T11726 26455-26463 Negative_regulation denotes decrease
T11725 26428-26436 Entity denotes promoter
T11724 26421-26427 Protein denotes IL-1RA
T11723 26412-26416 Protein denotes IL-6
T11722 26406-26410 Protein denotes IFNγ
T11721 26388-26392 Protein denotes NFAT
T11720 26315-26322 Binding denotes binding
T11719 26289-26292 Positive_regulation denotes due
T11718 26265-26272 Binding denotes binding
T11717 26254-26260 Protein denotes NFIL-6
T11716 26248-26249 Protein denotes 3
T11715 26241-26247 Protein denotes NFATP2
T11714 26228-26237 Positive_regulation denotes induction
T11713 26193-26203 Gene_expression denotes production
T11712 25923-25929 Protein denotes IL-1RA
T11711 25842-25848 Protein denotes IL-1RA
T11710 25834-25841 Positive_regulation denotes induced
T11709 25811-25816 Protein denotes IL-1β
T11708 25804-25810 Positive_regulation denotes induce
T11707 25771-25777 Protein denotes TSST-1
T11706 25637-25644 Binding denotes binding
T11705 25583-25588 Protein denotes IL-1β
T11704 25574-25578 Protein denotes TNFα
T11703 25503-25510 Binding denotes binding
T11702 25499-25502 Protein denotes p65
T11701 25451-25455 Protein denotes IL-8
T11700 25409-25413 Protein denotes IL-8
T11699 25394-25401 Binding denotes binding
T11698 25381-25387 Protein denotes NFATc2
T11697 25363-25369 Protein denotes NFIL-6
T11696 25355-25358 Protein denotes p65
T11695 25288-25301 Transcription denotes transcription
T11694 25283-25287 Protein denotes IL-8
T11693 25274-25282 Positive_regulation denotes mediated
T11692 25254-25267 Transcription denotes transcription
T11691 25249-25253 Protein denotes IL-8
T11690 25240-25248 Positive_regulation denotes mediated
T11689 25188-25190 Protein denotes 50
T11688 25184-25187 Protein denotes p65
T11687 25180-25183 Positive_regulation denotes via
T11686 25154-25156 Protein denotes 65
T11685 25150-25153 Protein denotes p65
T11684 25100-25113 Transcription denotes transcription
T11683 25095-25099 Protein denotes IL-8
T11682 25082-25091 Positive_regulation denotes induction
T11681 25000-25004 Protein denotes IL-8
T11680 24966-24969 Protein denotes p50
T11679 24936-24939 Protein denotes p65
T11678 24920-24927 Binding denotes binding
T11677 24899-24907 Positive_regulation denotes mediated
T11676 24804-24814 Gene_expression denotes production
T11675 24797-24803 Protein denotes IL-1RA
T11674 24778-24782 Protein denotes IL-8
T11673 24769-24777 Positive_regulation denotes mediated
T11672 24668-24674 Protein denotes IL-1RA
T11671 24659-24663 Protein denotes IL-8
T11670 24473-24477 Protein denotes NFAT
T11669 24388-24395 Binding denotes binding
T11668 24383-24387 Protein denotes NFAT
T11667 24301-24305 Protein denotes NFAT
T11666 24289-24295 Protein denotes NFIL-6
T11665 24271-24278 Binding denotes binding
T11664 24263-24270 Positive_regulation denotes induced
T11663 32024-32030 Protein denotes IL-1RA
T11662 31698-31702 Protein denotes NFAT
T11661 31602-31607 Protein denotes IL-1β
T11660 31587-31593 Protein denotes IL-1RA
T11659 31362-31368 Protein denotes TSST-1
T11658 31346-31352 Protein denotes TSST-1
T11657 31095-31099 Protein denotes IL-2
T11656 31080-31084 Protein denotes IL-1
T11655 31064-31070 Protein denotes TSST-1
T11654 30993-30998 Protein denotes IL-1β
T11653 30919-30925 Protein denotes TSST-1
T11652 30891-30897 Protein denotes IL-1RA
T11651 30885-30890 Protein denotes IL-1β
T11650 30851-30855 Protein denotes IL-1
T11649 30805-30810 Protein denotes IL-1β
T11648 30793-30799 Protein denotes IL-1RA
T11647 30702-30708 Protein denotes TSST-1
T11646 30674-30680 Protein denotes IL-1RA
T11645 30668-30673 Protein denotes IL-1β
T11644 30552-30558 Protein denotes IL-1RA
T11643 30537-30543 Protein denotes TSST-1
T11642 30364-30370 Protein denotes TSST-1
T11641 30158-30164 Protein denotes TSST-1
T11640 29948-29954 Protein denotes IL-1RA
T11639 29647-29653 Protein denotes IL-1RA
T11638 29634-29638 Protein denotes TNFα
T11637 29432-29438 Protein denotes IL-1RA
T11636 29349-29353 Protein denotes TNFα
T11635 29305-29311 Protein denotes TSST-1
T11634 29149-29155 Protein denotes TSST-1
T11633 29096-29102 Protein denotes TSST-1
T11632 29068-29074 Protein denotes IL-1RA
T11631 28960-28966 Protein denotes IL-1RA
T11630 28945-28951 Protein denotes TSST-1
T11629 28869-28873 Protein denotes TNFα
T11628 28820-28826 Protein denotes TSST-1
T11627 28774-28778 Protein denotes IFNγ
T11626 28766-28770 Protein denotes IL-6
T11625 28759-28764 Protein denotes IL-1β
T11624 28753-28757 Protein denotes TNFα
T11623 28722-28728 Protein denotes IL-1RA
T11622 28713-28717 Protein denotes IL-8
T11621 28660-28664 Protein denotes NFAT
T11620 28649-28655 Protein denotes NFIL-6
T11619 28617-28623 Protein denotes TSST-1
T11618 28540-28546 Protein denotes IL-1RA
T11617 28476-28480 Protein denotes IL-6
T11616 28466-28471 Protein denotes IL-1β
T11615 28386-28392 Protein denotes IL-1RA
T11614 28380-28385 Protein denotes IL-1β
T11613 28365-28371 Protein denotes TSST-1
T11612 28201-28207 Protein denotes TSST-1
T11611 27682-27688 Protein denotes IL-1RA
T11610 27651-27655 Protein denotes IL-8
T11609 27548-27576 Protein denotes p38 mitogen-activated kinase
T11608 27512-27516 Protein denotes TNFα
T11607 27503-27507 Protein denotes IFNγ
T11606 27388-27394 Protein denotes TSST-1
T11605 27347-27351 Protein denotes TNFα
T11604 27222-27242 Protein denotes Toll-like receptor 4
T11603 27161-27167 Protein denotes TSST-1
T11602 27076-27082 Protein denotes TSST-1
T11601 26946-26952 Protein denotes IL-1RA
T11600 26933-26937 Protein denotes IL-8
T11599 26822-26828 Protein denotes IL-1RA
T11598 26708-26714 Protein denotes IL-1RA
T11597 26543-26549 Protein denotes IL-1RA
T11596 26513-26519 Protein denotes IL-1RA
T11595 26482-26488 Protein denotes NFIL-6
T11594 26473-26477 Protein denotes NFAT
T11593 26421-26427 Protein denotes IL-1RA
T11592 26412-26416 Protein denotes IL-6
T11591 26406-26410 Protein denotes IFNγ
T11590 26388-26392 Protein denotes NFAT
T11589 26254-26260 Protein denotes NFIL-6
T11588 26248-26249 Protein denotes 3
T11587 26241-26247 Protein denotes NFATP2
T11586 25923-25929 Protein denotes IL-1RA
T11585 25842-25848 Protein denotes IL-1RA
T11584 25811-25816 Protein denotes IL-1β
T11583 25771-25777 Protein denotes TSST-1
T11582 25583-25588 Protein denotes IL-1β
T11581 25574-25578 Protein denotes TNFα
T11580 25499-25502 Protein denotes p65
T11579 25451-25455 Protein denotes IL-8
T11578 25409-25413 Protein denotes IL-8
T11577 25381-25387 Protein denotes NFATc2
T11576 25363-25369 Protein denotes NFIL-6
T11575 25355-25358 Protein denotes p65
T11574 25283-25287 Protein denotes IL-8
T11573 25249-25253 Protein denotes IL-8
T11572 25188-25190 Protein denotes 50
T11571 25184-25187 Protein denotes p65
T11570 25154-25156 Protein denotes 65
T11569 25150-25153 Protein denotes p65
T11568 25095-25099 Protein denotes IL-8
T11567 25000-25004 Protein denotes IL-8
T11566 24966-24969 Protein denotes p50
T11565 24936-24939 Protein denotes p65
T11564 24797-24803 Protein denotes IL-1RA
T11563 24778-24782 Protein denotes IL-8
T11562 24668-24674 Protein denotes IL-1RA
T11561 24659-24663 Protein denotes IL-8
T11560 24473-24477 Protein denotes NFAT
T11559 24383-24387 Protein denotes NFAT
T11558 24301-24305 Protein denotes NFAT
T11789 29068-29074 Protein denotes IL-1RA
T11788 28967-28977 Gene_expression denotes production
T11787 28960-28966 Protein denotes IL-1RA
T11786 28952-28959 Positive_regulation denotes induced
T11785 28945-28951 Protein denotes TSST-1
T11784 28917-28925 Positive_regulation denotes mediated
T11783 28869-28873 Protein denotes TNFα
T11782 28835-28842 Binding denotes binding
T11781 28827-28834 Positive_regulation denotes induced
T11780 28820-28826 Protein denotes TSST-1
T11779 28774-28778 Protein denotes IFNγ
T11778 28766-28770 Protein denotes IL-6
T11777 28759-28764 Protein denotes IL-1β
T11776 28753-28757 Protein denotes TNFα
T11775 28729-28737 Entity denotes promoter
T11774 28722-28728 Protein denotes IL-1RA
T11557 24289-24295 Protein denotes NFIL-6
T10435 22797-22804 Localization denotes release
T10434 22790-22796 Protein denotes IL-1RA
T10433 22780-22789 Negative_regulation denotes decreased
T10432 22771-22774 Positive_regulation denotes led
T10431 22704-22711 Binding denotes binding
T10430 22572-22578 Protein denotes IL-1RA
T10429 22478-22488 Negative_regulation denotes inhibition
T10428 22460-22466 Protein denotes IL-1RA
T10427 22448-22456 Negative_regulation denotes decrease
T10426 22319-22325 Protein denotes IL-1RA
T10425 22091-22098 Binding denotes binding
T10424 22069-22078 Negative_regulation denotes reduction
T10423 22023-22029 Protein denotes IL-1RA
T10422 22007-22013 Protein denotes IL-1RA
T10421 21994-22003 Negative_regulation denotes reduction
T10420 21974-21980 Protein denotes IL-1RA
T10419 21921-21928 Binding denotes binding
T10418 21906-21920 Negative_regulation denotes down-regulated
T10417 21876-21885 Negative_regulation denotes overruled
T10416 21850-21853 Positive_regulation denotes via
T10415 21843-21849 Protein denotes NFIL-6
T10414 21831-21834 Positive_regulation denotes via
T10413 21826-21830 Protein denotes NFAT
T10412 21754-21760 Protein denotes IL-1RA
T10411 21741-21750 Positive_regulation denotes induction
T10410 21704-21710 Protein denotes IL-1RA
T10409 21591-21597 Protein denotes IL-1RA
T10408 21583-21590 Negative_regulation denotes reduced
T10407 22790-22796 Protein denotes IL-1RA
T10406 22572-22578 Protein denotes IL-1RA
T10405 22460-22466 Protein denotes IL-1RA
T10404 22319-22325 Protein denotes IL-1RA
T10403 22023-22029 Protein denotes IL-1RA
T10402 22007-22013 Protein denotes IL-1RA
T10401 21974-21980 Protein denotes IL-1RA
T10400 21843-21849 Protein denotes NFIL-6
T10399 21826-21830 Protein denotes NFAT
T10398 21754-21760 Protein denotes IL-1RA
T10397 21704-21710 Protein denotes IL-1RA
T10396 21591-21597 Protein denotes IL-1RA
T9553 20743-20749 Protein denotes TSST-1
T9552 20730-20736 Protein denotes TSST-1
T9551 20706-20712 Protein denotes TSST-1
T9550 20691-20700 Positive_regulation denotes following
T9549 20663-20667 Protein denotes IL-2
T9548 20652-20659 Localization denotes release
T9547 20642-20651 Regulation denotes dependent
T9546 20637-20641 Protein denotes IL-1
T9545 20621-20629 Negative_regulation denotes decrease
T9544 20526-20531 Protein denotes IL-1β
T9543 20511-20517 Protein denotes IL-1RA
T9542 20497-20507 Gene_expression denotes production
T9541 20490-20496 Positive_regulation denotes higher
T9540 20332-20338 Protein denotes TSST-1
T9539 20310-20316 Protein denotes TSST-1
T9538 20272-20278 Protein denotes TSST-1
T9537 20186-20192 Protein denotes IL-1RA
T9536 20180-20185 Protein denotes IL-1β
T9535 20032-20038 Protein denotes IL-1RA
T9534 20021-20026 Protein denotes IL-1β
T9533 19993-20001 Positive_regulation denotes resulted
T9532 19899-19905 Protein denotes IL-1RA
T9531 19893-19898 Protein denotes IL-1β
T9530 19784-19790 Protein denotes IL-1RA
T9529 19774-19779 Protein denotes IL-1β
T9528 19696-19702 Protein denotes IL-1RA
T9527 19690-19695 Protein denotes IL-1β
T9526 19682-19689 Positive_regulation denotes induced
T9525 19675-19681 Protein denotes TSST-1
T9524 19661-19670 Regulation denotes modulated
T9523 20743-20749 Protein denotes TSST-1
T9522 20730-20736 Protein denotes TSST-1
T9521 20706-20712 Protein denotes TSST-1
T9520 20663-20667 Protein denotes IL-2
T9519 20637-20641 Protein denotes IL-1
T9518 20526-20531 Protein denotes IL-1β
T9517 20511-20517 Protein denotes IL-1RA
T9516 20332-20338 Protein denotes TSST-1
T9515 20310-20316 Protein denotes TSST-1
T9514 20272-20278 Protein denotes TSST-1
T9513 20186-20192 Protein denotes IL-1RA
T9512 20180-20185 Protein denotes IL-1β
T9511 20032-20038 Protein denotes IL-1RA
T9510 20021-20026 Protein denotes IL-1β
T9509 19899-19905 Protein denotes IL-1RA
T9508 19893-19898 Protein denotes IL-1β
T9507 19784-19790 Protein denotes IL-1RA
T9506 19774-19779 Protein denotes IL-1β
T9505 19696-19702 Protein denotes IL-1RA
T9504 19690-19695 Protein denotes IL-1β
T9503 19675-19681 Protein denotes TSST-1
T7951 16227-16231 Protein denotes NFAT
T7950 16216-16222 Protein denotes NFIL-6
T8007 18348-18356 Positive_regulation denotes elevated
T8006 18336-18342 Protein denotes TSST-1
T8005 18301-18307 Protein denotes TSST-1
T8004 18251-18260 Positive_regulation denotes following
T8003 18246-18250 Entity denotes site
T8002 18222-18229 Binding denotes binding
T8001 17906-17912 Protein denotes TSST-1
T8000 17860-17867 Binding denotes binding
T7999 17850-17859 Positive_regulation denotes increased
T7998 17839-17846 Positive_regulation denotes induced
T7997 17832-17838 Protein denotes TSST-1
T7996 17547-17561 Negative_regulation denotes down-regulated
T7995 17497-17504 Binding denotes binding
T7994 17468-17474 Protein denotes TSST-1
T7993 17423-17429 Protein denotes TSST-1
T7992 17328-17335 Binding denotes Binding
T7991 17291-17297 Protein denotes TSST-1
T7990 17230-17236 Protein denotes TSST-1
T7989 17096-17102 Protein denotes TSST-1
T7988 17000-17006 Protein denotes TSST-1
T7987 16989-16996 Positive_regulation denotes induced
T7986 16981-16988 Binding denotes binding
T7985 16620-16626 Protein denotes IL-1RA
T7984 16607-16612 Entity denotes sites
T7983 16503-16509 Protein denotes IL-1RA
T7982 16482-16486 Binding denotes bind
T7981 16413-16417 Protein denotes IFNγ
T7980 16405-16409 Protein denotes IL-6
T7979 16399-16403 Protein denotes TNFα
T7978 16340-16347 Positive_regulation denotes induced
T7977 16304-16314 Gene_expression denotes expression
T7976 16297-16303 Protein denotes IL-1RA
T7975 16289-16296 Positive_regulation denotes induced
T7974 16282-16288 Protein denotes TSST-1
T7973 16249-16255 Protein denotes TSST-1
T7972 16232-16239 Binding denotes binding
T7971 16227-16231 Protein denotes NFAT
T7970 16216-16222 Protein denotes NFIL-6
T7969 18336-18342 Protein denotes TSST-1
T7968 18301-18307 Protein denotes TSST-1
T7967 17906-17912 Protein denotes TSST-1
T7966 17832-17838 Protein denotes TSST-1
T7965 17468-17474 Protein denotes TSST-1
T7964 17423-17429 Protein denotes TSST-1
T7963 17291-17297 Protein denotes TSST-1
T7962 17230-17236 Protein denotes TSST-1
T7961 17096-17102 Protein denotes TSST-1
T7960 17000-17006 Protein denotes TSST-1
T7959 16620-16626 Protein denotes IL-1RA
T7958 16503-16509 Protein denotes IL-1RA
T7957 16413-16417 Protein denotes IFNγ
T7956 16405-16409 Protein denotes IL-6
T7955 16399-16403 Protein denotes TNFα
T7954 16297-16303 Protein denotes IL-1RA
T7953 16282-16288 Protein denotes TSST-1
T7952 16249-16255 Protein denotes TSST-1
T4673 14725-14731 Protein denotes IL-1RA
T4672 14707-14714 Positive_regulation denotes induced
T4671 14700-14706 Protein denotes TSST-1
T4670 14687-14695 Positive_regulation denotes elevated
T4669 14620-14626 Protein denotes TSST-1
T4668 14539-14545 Protein denotes TSST-1
T4667 14492-14502 Gene_expression denotes production
T4666 14485-14491 Protein denotes IL-1RA
T4665 14473-14481 Positive_regulation denotes increase
T4664 14443-14449 Protein denotes TSST-1
T4663 14407-14417 Gene_expression denotes production
T4662 14400-14406 Protein denotes IL-1RA
T4661 14368-14373 Regulation denotes alter
T4660 14238-14247 Positive_regulation denotes following
T4659 14203-14211 Gene_expression denotes produced
T4658 14164-14170 Protein denotes IL-1RA
T4657 14158-14162 Protein denotes IL-8
T4656 14096-14102 Protein denotes TSST-1
T4655 14083-14089 Protein denotes TSST-1
T4654 14059-14065 Protein denotes TSST-1
T4653 14044-14053 Positive_regulation denotes following
T4652 14033-14043 Gene_expression denotes production
T4651 14028-14032 Protein denotes IL-8
T4650 14014-14024 Negative_regulation denotes alteration
T4649 13941-13951 Gene_expression denotes production
T4648 13936-13940 Protein denotes IL-8
T4647 13924-13932 Positive_regulation denotes increase
T4646 13894-13902 Positive_regulation denotes resulted
T4645 13780-13790 Gene_expression denotes production
T4644 13775-13779 Protein denotes IL-8
T4643 13753-13760 Positive_regulation denotes induced
T4642 13626-13632 Protein denotes TSST-1
T4641 13613-13619 Protein denotes TSST-1
T4640 13589-13595 Protein denotes TSST-1
T4639 13569-13579 Gene_expression denotes production
T4638 13564-13568 Protein denotes IL-6
T4637 13554-13563 Negative_regulation denotes decreased
T4636 13505-13515 Gene_expression denotes production
T4635 13500-13504 Protein denotes IL-6
T4634 13492-13499 Positive_regulation denotes induced
T4633 13470-13480 Negative_regulation denotes alteration
T4632 13436-13440 Protein denotes IL-6
T4631 13405-13412 Positive_regulation denotes induced
T4630 12146-12151 Protein denotes IL-1β
T4629 12128-12135 Positive_regulation denotes induced
T4628 12121-12127 Protein denotes TSST-1
T4627 12104-12113 Negative_regulation denotes reduction
T4626 12039-12045 Protein denotes TSST-1
T4625 12001-12007 Protein denotes TSST-1
T4624 11932-11937 Protein denotes IL-1β
T4623 11919-11928 Negative_regulation denotes reduction
T4622 11889-11895 Protein denotes TSST-1
T4621 11819-11829 Gene_expression denotes production
T4620 11813-11818 Protein denotes IL-1β
T4619 11796-11809 Positive_regulation denotes up-regulation
T4618 11732-11741 Positive_regulation denotes following
T4617 11710-11720 Gene_expression denotes production
T4616 11704-11709 Protein denotes IL-1β
T4615 11671-11677 Protein denotes TSST-1
T4614 11095-11099 Protein denotes IFNγ
T4613 11089-11093 Protein denotes IL-6
T4612 11083-11087 Protein denotes IL-8
T4611 11077-11081 Protein denotes TNFα
T4610 11063-11073 Gene_expression denotes production
T4609 11055-11059 Positive_regulation denotes lead
T4608 10981-10985 Protein denotes IFNγ
T4607 10972-10976 Protein denotes IL-6
T4606 10966-10970 Protein denotes IL-8
T4605 10960-10964 Protein denotes TNFα
T4604 10861-10867 Protein denotes TSST-1
T4603 16160-16166 Protein denotes TSST-1
T4602 16147-16153 Protein denotes TSST-1
T4601 16103-16109 Protein denotes TSST-1
T4600 16001-16007 Protein denotes TGFβ 1
T4599 15991-15996 Protein denotes IL-10
T4598 15985-15989 Protein denotes IL-4
T4597 15978-15983 Protein denotes IL-12
T4596 15972-15976 Protein denotes IL-2
T4595 15948-15953 Protein denotes TGFβ1
T4594 15941-15946 Protein denotes IL-10
T4593 15935-15939 Protein denotes IL-4
T4592 15928-15933 Protein denotes IL-12
T4591 15922-15926 Protein denotes IL-2
T4590 15884-15890 Protein denotes TSST-1
T4589 15871-15877 Protein denotes TSST-1
T4588 15829-15835 Protein denotes TSST-1
T4587 15703-15707 Protein denotes IFNγ
T4586 15598-15602 Protein denotes IFNγ
T4585 15590-15594 Protein denotes IFNγ
T4584 15449-15453 Protein denotes TNFα
T4583 15392-15398 Protein denotes TSST-1
T4582 15379-15385 Protein denotes TSST-1
T4581 15291-15295 Protein denotes TNFα
T4580 15142-15146 Protein denotes TNFα
T4579 15121-15125 Protein denotes TNFα
T4578 15044-15050 Protein denotes IL-1RA
T4577 15035-15039 Protein denotes IL-8
T4576 14924-14930 Protein denotes IL-1RA
T4575 14915-14919 Protein denotes IL-8
T4574 14814-14820 Protein denotes IL-1RA
T4573 14805-14809 Protein denotes IL-8
T4572 14725-14731 Protein denotes IL-1RA
T4571 14700-14706 Protein denotes TSST-1
T4570 14620-14626 Protein denotes TSST-1
T4569 14539-14545 Protein denotes TSST-1
T4568 14485-14491 Protein denotes IL-1RA
T4567 14443-14449 Protein denotes TSST-1
T4566 14400-14406 Protein denotes IL-1RA
T4565 14164-14170 Protein denotes IL-1RA
T4564 14158-14162 Protein denotes IL-8
T4563 14143-14149 Protein denotes IL-1RA
T4562 14096-14102 Protein denotes TSST-1
T4561 14083-14089 Protein denotes TSST-1
T4560 14059-14065 Protein denotes TSST-1
T4559 14028-14032 Protein denotes IL-8
T4558 13936-13940 Protein denotes IL-8
T4557 13775-13779 Protein denotes IL-8
T4556 13731-13735 Protein denotes IL-8
T4555 13626-13632 Protein denotes TSST-1
T4554 13613-13619 Protein denotes TSST-1
T4553 13589-13595 Protein denotes TSST-1
T4552 13564-13568 Protein denotes IL-6
T4551 13500-13504 Protein denotes IL-6
T4550 13436-13440 Protein denotes IL-6
T4549 13397-13401 Protein denotes IL-6
T4548 12146-12151 Protein denotes IL-1β
T4547 12121-12127 Protein denotes TSST-1
T4546 12039-12045 Protein denotes TSST-1
T4545 12001-12007 Protein denotes TSST-1
T4544 11932-11937 Protein denotes IL-1β
T4543 11889-11895 Protein denotes TSST-1
T4542 11813-11818 Protein denotes IL-1β
T4541 11704-11709 Protein denotes IL-1β
T4540 11685-11690 Protein denotes IL-1β
T4539 11671-11677 Protein denotes TSST-1
T4538 11095-11099 Protein denotes IFNγ
T4537 11089-11093 Protein denotes IL-6
T4536 11083-11087 Protein denotes IL-8
T4535 11077-11081 Protein denotes TNFα
T4534 10981-10985 Protein denotes IFNγ
T4533 10972-10976 Protein denotes IL-6
T4532 10966-10970 Protein denotes IL-8
T4531 10960-10964 Protein denotes TNFα
T4530 10891-10897 Protein denotes TSST-1
T4529 10861-10867 Protein denotes TSST-1
T4717 16160-16166 Protein denotes TSST-1
T4716 16147-16153 Protein denotes TSST-1
T4715 16103-16109 Protein denotes TSST-1
T4714 16016-16023 Positive_regulation denotes induced
T4713 16001-16007 Protein denotes TGFβ 1
T4712 15991-15996 Protein denotes IL-10
T4711 15985-15989 Protein denotes IL-4
T4710 15978-15983 Protein denotes IL-12
T4709 15972-15976 Protein denotes IL-2
T4708 15958-15968 Gene_expression denotes production
T4707 15941-15946 Protein denotes IL-10
T4706 15935-15939 Protein denotes IL-4
T4705 15928-15933 Protein denotes IL-12
T4704 15922-15926 Protein denotes IL-2
T4703 15884-15890 Protein denotes TSST-1
T4702 15871-15877 Protein denotes TSST-1
T4701 15829-15835 Protein denotes TSST-1
T4700 15798-15813 Negative_regulation denotes down-regulation
T4699 15719-15728 Positive_regulation denotes following
T4698 15708-15718 Gene_expression denotes production
T4697 15703-15707 Protein denotes IFNγ
T4696 15691-15699 Positive_regulation denotes increase
T4695 15629-15638 Positive_regulation denotes following
T4694 15603-15613 Gene_expression denotes production
T4693 15598-15602 Protein denotes IFNγ
T4692 15454-15463 Localization denotes secretion
T4691 15449-15453 Protein denotes TNFα
T4690 15439-15445 Regulation denotes effect
T4689 15392-15398 Protein denotes TSST-1
T4688 15379-15385 Protein denotes TSST-1
T4687 15296-15306 Gene_expression denotes production
T4686 15291-15295 Protein denotes TNFα
T4685 15280-15286 Regulation denotes change
T4684 15147-15157 Gene_expression denotes production
T4683 15142-15146 Protein denotes TNFα
T4682 15121-15125 Protein denotes TNFα
T4681 15044-15050 Protein denotes IL-1RA
T4680 15035-15039 Protein denotes IL-8
T4679 15009-15016 Positive_regulation denotes induced
T4678 14924-14930 Protein denotes IL-1RA
T4677 14915-14919 Protein denotes IL-8
T4676 14814-14820 Protein denotes IL-1RA
T4675 14805-14809 Protein denotes IL-8
T4674 14797-14804 Positive_regulation denotes induced
T993 2732-2740 Protein denotes Dectin-1
T994 3007-3015 Protein denotes Dectin-1
T995 3042-3046 Protein denotes TNFα
T996 3055-3075 Protein denotes Toll-like receptor 2
T997 3100-3105 Protein denotes MyD88
T998 3202-3208 Protein denotes NFIL-6
T999 3461-3465 Protein denotes IL-1
T1000 3467-3471 Protein denotes IL-6
T1001 3473-3477 Protein denotes TNFα
T1002 3549-3555 Protein denotes IL-1RA
T1003 3565-3569 Protein denotes IL-1
T1004 3771-3775 Protein denotes IL-8
T1005 4917-4923 Protein denotes TSST-1
T1006 5048-5052 Protein denotes TNFα
T1007 5054-5059 Protein denotes IL-1β
T1008 5061-5065 Protein denotes IL-6
T1009 5067-5071 Protein denotes IL-8
T1010 5076-5082 Protein denotes IL-1RA
T1011 5108-5112 Protein denotes IFNγ
T1012 5114-5118 Protein denotes IL-2
T1013 5120-5124 Protein denotes IL-4
T1014 5126-5131 Protein denotes IL-10
T1015 5133-5138 Protein denotes IL-12
T1016 5143-5148 Protein denotes TGFβ1
T1017 5192-5196 Protein denotes TNFα
T1018 5266-5270 Protein denotes IL-8
T1019 5308-5312 Protein denotes IFNγ
T1020 5371-5375 Protein denotes IL-6
T1021 5446-5452 Protein denotes IL-1RA
T1022 5508-5514 Protein denotes IL-1RA
T1023 5627-5633 Protein denotes IL-1RA
T1024 5822-5828 Protein denotes IL-1RA
T1025 2620-2628 Positive_regulation denotes mediated
T1026 2732-2740 Protein denotes Dectin-1
T1027 2985-2992 Binding denotes binding
T1028 3007-3015 Protein denotes Dectin-1
T1029 3016-3024 Positive_regulation denotes resulted
T1030 3028-3038 Gene_expression denotes production
T1031 3042-3046 Protein denotes TNFα
T1032 3055-3075 Protein denotes Toll-like receptor 2
T1033 3100-3105 Protein denotes MyD88
T1034 3202-3208 Protein denotes NFIL-6
T1035 3420-3429 Localization denotes secretion
T1036 3461-3465 Protein denotes IL-1
T1037 3467-3471 Protein denotes IL-6
T1038 3473-3477 Protein denotes TNFα
T1039 3513-3523 Gene_expression denotes production
T1040 3549-3555 Protein denotes IL-1RA
T1041 3565-3569 Protein denotes IL-1
T1042 3631-3638 Positive_regulation denotes induced
T1043 3763-3770 Gene_expression denotes produce
T1044 3771-3775 Protein denotes IL-8
T1045 3776-3790 Positive_regulation denotes in response to
T1046 4385-4392 Regulation denotes effects
T1047 4917-4923 Protein denotes TSST-1
T1048 4988-4994 Regulation denotes effect
T1049 5048-5052 Protein denotes TNFα
T1050 5054-5059 Protein denotes IL-1β
T1051 5061-5065 Protein denotes IL-6
T1052 5067-5071 Protein denotes IL-8
T1053 5076-5082 Protein denotes IL-1RA
T1054 5108-5112 Protein denotes IFNγ
T1055 5114-5118 Protein denotes IL-2
T1056 5120-5124 Protein denotes IL-4
T1057 5126-5131 Protein denotes IL-10
T1058 5133-5138 Protein denotes IL-12
T1059 5143-5148 Protein denotes TGFβ1
T1060 5192-5196 Protein denotes TNFα
T1061 5266-5270 Protein denotes IL-8
T1062 5308-5312 Protein denotes IFNγ
T1063 5371-5375 Protein denotes IL-6
T1064 5446-5452 Protein denotes IL-1RA
T1065 5468-5475 Binding denotes binding
T1066 5508-5514 Protein denotes IL-1RA
T1067 5515-5523 Entity denotes promoter
T1068 5627-5633 Protein denotes IL-1RA
T1069 5800-5807 Binding denotes binding
T1070 5822-5828 Protein denotes IL-1RA
T3084 5877-5883 Protein denotes NFIL-6
T3085 5888-5892 Protein denotes NFAT
T3086 5916-5920 Protein denotes TNFα
T3087 5922-5926 Protein denotes IL-6
T3088 5931-5935 Protein denotes IFNγ
T3089 5996-6002 Protein denotes TSST-1
T3090 6026-6032 Protein denotes TSST-1
T3091 6098-6104 Protein denotes NFIL-6
T3092 6187-6191 Protein denotes TNFα
T3093 6223-6227 Protein denotes IL-8
T3094 6263-6267 Protein denotes IL-6
T3095 6397-6403 Protein denotes TSST-1
T3096 6475-6479 Protein denotes IL-8
T3097 6544-6547 Protein denotes p65
T3098 6574-6577 Protein denotes p50
T3099 6689-6692 Protein denotes p65
T3100 6718-6721 Protein denotes p50
T3101 6731-6734 Protein denotes p52
T3102 6863-6867 Protein denotes TNFα
T3103 6934-6940 Protein denotes TSST-1
T3104 6979-6985 Protein denotes TSST-1
T3105 7063-7069 Protein denotes TSST-1
T3106 7100-7106 Protein denotes TSST-1
T3107 7130-7136 Protein denotes TSST-1
T3108 7235-7239 Protein denotes NFAT
T3109 7261-7265 Protein denotes IFNγ
T3110 7308-7312 Protein denotes NFAT
T3111 7359-7365 Protein denotes NFATc2
T3112 7392-7398 Protein denotes NFATc1
T3113 5849-5856 Binding denotes Binding
T3114 5877-5883 Protein denotes NFIL-6
T3115 5888-5892 Protein denotes NFAT
T3116 5916-5920 Protein denotes TNFα
T3117 5922-5926 Protein denotes IL-6
T3118 5931-5935 Protein denotes IFNγ
T3119 5936-5945 Entity denotes promoters
T3120 5946-5955 Positive_regulation denotes following
T3121 5996-6002 Protein denotes TSST-1
T3122 6068-6075 Binding denotes binding
T3123 6098-6104 Protein denotes NFIL-6
T3124 6187-6191 Protein denotes TNFα
T3125 6223-6227 Protein denotes IL-8
T3126 6263-6267 Protein denotes IL-6
T3127 6327-6334 Positive_regulation denotes induced
T3128 6397-6403 Protein denotes TSST-1
T3129 6475-6479 Protein denotes IL-8
T3130 6508-6515 Positive_regulation denotes induced
T3131 6528-6535 Binding denotes binding
T3132 6544-6547 Protein denotes p65
T3133 6574-6577 Protein denotes p50
T3134 6673-6680 Binding denotes binding
T3135 6689-6692 Protein denotes p65
T3136 6718-6721 Protein denotes p50
T3137 6731-6734 Protein denotes p52
T3138 6823-6830 Positive_regulation denotes induced
T3139 6836-6843 Binding denotes binding
T3140 6863-6867 Protein denotes TNFα
T3141 6920-6929 Negative_regulation denotes decreased
T3142 6934-6940 Protein denotes TSST-1
T3143 6941-6948 Positive_regulation denotes induced
T3144 6954-6961 Binding denotes binding
T3145 6979-6985 Protein denotes TSST-1
T3146 7063-7069 Protein denotes TSST-1
T3147 7100-7106 Protein denotes TSST-1
T3148 7130-7136 Protein denotes TSST-1
T3149 7201-7208 Binding denotes binding
T3150 7235-7239 Protein denotes NFAT
T3151 7261-7265 Protein denotes IFNγ
T3152 7308-7312 Protein denotes NFAT
T3153 7340-7347 Positive_regulation denotes induced
T3154 7348-7355 Binding denotes binding
T3155 7359-7365 Protein denotes NFATc2
T3156 7392-7398 Protein denotes NFATc1
R66 T172 T170 themeOf IL-6,reduction
R67 T173 T174 causeOf TSST-1,induced
R68 T175 T174 themeOf IL-1β,induced
R69 T176 T174 themeOf IL-1RA,induced
R70 T178 T179 causeOf TSST-1,induced
R71 T179 T177 themeOf induced,decreased
R72 T180 T181 causeOf IL-1,dependent
R73 T182 T181 themeOf production,dependent
R74 T183 T182 themeOf IL-2,production
R75 T186 T185 themeOf IL-1RA,regulation
R371 T1027 T1029 causeOf binding,resulted
R372 T1028 T1029 causeOf Dectin-1,resulted
R373 T1028 T1027 themeOf Dectin-1,binding
R374 T1030 T1029 themeOf production,resulted
R375 T1031 T1030 themeOf TNFα,production
R376 T1032 T1030 themeOf Toll-like receptor 2,production
R377 T1033 T1030 themeOf MyD88,production
R378 T1036 T1035 themeOf IL-1,secretion
R379 T1037 T1035 themeOf IL-6,secretion
R380 T1038 T1035 themeOf TNFα,secretion
R381 T1039 T1042 themeOf production,induced
R382 T1040 T1039 themeOf IL-1RA,production
R383 T1041 T1039 themeOf IL-1,production
R384 T1041 T1042 themeOf IL-1,induced
R385 T1043 T1045 themeOf produce,in response to
R386 T1044 T1043 themeOf IL-8,produce
R387 T1044 T1045 themeOf IL-8,in response to
R388 T1067 T1065 themeOf promoter,binding
R389 T1067 T1066 partOf promoter,IL-1RA
R390 T1070 T1069 themeOf IL-1RA,binding
R7533 T11665 T11664 themeOf binding,induced
R7534 T11666 T11665 themeOf NFIL-6,binding
R7535 T11667 T11665 themeOf NFAT,binding
R7536 T11668 T11669 themeOf NFAT,binding
R7537 T11674 T11676 themeOf IL-8,production
R7538 T11675 T11676 themeOf IL-1RA,production
R7539 T11676 T11673 themeOf production,mediated
R7540 T11678 T11677 themeOf binding,mediated
R7541 T11679 T11678 themeOf p65,binding
R7542 T11680 T11678 themeOf p50,binding
R7543 T11682 T11687 themeOf induction,via
R7544 T11683 T11684 themeOf IL-8,transcription
R7545 T11684 T11682 themeOf transcription,induction
R7546 T11691 T11692 themeOf IL-8,transcription
R7547 T11692 T11690 themeOf transcription,mediated
R7548 T11694 T11695 themeOf IL-8,transcription
R7549 T11695 T11693 themeOf transcription,mediated
R7550 T11696 T11699 themeOf p65,binding
R7551 T11697 T11699 themeOf NFIL-6,binding
R7552 T11698 T11699 themeOf NFATc2,binding
R7553 T11700 T11699 themeOf IL-8,binding
R7554 T11702 T11703 themeOf p65,binding
R7556 T11709 T11708 themeOf IL-1β,induce
R7557 T11711 T11710 themeOf IL-1RA,induced
R7558 T11714 T11719 themeOf induction,due
R7559 T11715 T11718 themeOf NFATP2,binding
R7560 T11716 T11718 themeOf 3,binding
R7561 T11717 T11718 themeOf NFIL-6,binding
R7562 T11718 T11719 themeOf binding,due
R7563 T11718 T11714 themeOf binding,induction
R7564 T11725 T11720 themeOf promoter,binding
R7565 T11726 T11732 themeOf decrease,induced
R7566 T11727 T11729 themeOf NFAT,binding
R7567 T11727 T11726 themeOf NFAT,decrease
R7568 T11728 T11729 themeOf NFIL-6,binding
R7569 T11729 T11726 themeOf binding,decrease
R7570 T11734 T11733 themeOf induction,necessary
R7571 T11735 T11734 themeOf IL-1RA,induction
R7572 T11737 T11736 themeOf IL-1RA,produce
R7573 T11739 T11738 themeOf IL-8,produce
R7574 T11740 T11738 themeOf IL-1RA,produce
R7575 T11746 T11747 themeOf TSST-1,binding
R7576 T11749 T11748 themeOf IFNγ,release
R7577 T11750 T11748 themeOf TNFα,release
R7578 T11754 T11753 themeOf IL-8,attracting
R7579 T11754 T11752 themeOf IL-8,induction
R7580 T11755 T11752 themeOf IL-1RA,induction
R7581 T11758 T11759 causeOf TSST-1,induced
R7582 T11759 T11757 themeOf induced,altered
R7583 T11760 T11759 themeOf IL-1β,induced
R7584 T11761 T11759 themeOf IL-1RA,induced
R7585 T11763 T11762 themeOf IL-1β,down-regulation
R7586 T11764 T11762 themeOf IL-6,down-regulation
R7587 T11766 T11765 themeOf IL-1RA,up-regulation
R7588 T11768 T11769 causeOf TSST-1,induced
R7589 T11770 T11769 themeOf binding,induced
R7590 T11771 T11770 themeOf NFIL-6,binding
R7591 T11772 T11770 themeOf NFAT,binding
R7592 T11780 T11781 causeOf TSST-1,induced
R7593 T11782 T11781 themeOf binding,induced
R7594 T11783 T11782 themeOf TNFα,binding
R7595 T11785 T11786 causeOf TSST-1,induced
R7596 T11787 T11788 themeOf IL-1RA,production
R7597 T11788 T11786 themeOf production,induced
R7598 T11790 T11792 themeOf TSST-1,binding
R7599 T11790 T11795 themeOf TSST-1,binding
R7600 T11791 T11796 themeOf induced,increased
R7601 T11792 T11791 themeOf binding,induced
R7602 T11793 T11795 themeOf TSST-1,binding
R7603 T11794 T11796 themeOf induced,increased
R7604 T11795 T11794 themeOf binding,induced
R7605 T11795 T11796 themeOf binding,increased
R7606 T11798 T11799 causeOf TSST-1,induced
R7607 T11798 T11797 themeOf TSST-1,down-regulation
R7608 T11799 T11797 themeOf induced,down-regulation
R7609 T11800 T11797 themeOf binding,down-regulation
R7610 T11800 T11799 themeOf binding,induced
R7611 T11807 T11808 themeOf TSST-1,binding
R7612 T11810 T11812 themeOf TSST-1,binding
R7613 T11811 T11809 themeOf induced,increase
R7614 T11812 T11811 themeOf binding,induced
R7615 T11812 T11809 themeOf binding,increase
R7616 T11814 T11815 causeOf TSST-1,induced
R7617 T11816 T11817 themeOf IL-1RA,production
R7618 T11817 T11815 themeOf production,induced
R7619 T11817 T11813 themeOf production,up-regulation
R7620 T11818 T11821 themeOf decrease,following
R7621 T11819 T11818 themeOf IL-1β,decrease
R7622 T11820 T11818 themeOf IL-1RA,decrease
R7623 T11822 T11821 causeOf TSST-1,following
R7624 T11827 T11826 themeOf IL-1,effects
R7625 T11831 T11830 causeOf TSST-1,following
R7626 T11836 T11837 causeOf TSST-1,induced
R7627 T11837 T11835 themeOf induced,reduced
R7628 T11838 T11839 causeOf IL-1,dependent
R7629 T11840 T11841 themeOf IL-2,production
R7630 T11841 T11839 themeOf production,dependent
R7631 T11845 T11847 themeOf -1RA,production
R7632 T11846 T11847 themeOf IL-1β,production
R7633 T11847 T11844 themeOf production,controls
R7634 T11850 T11849 themeOf IL-1RA,activated
R12464 T18265 T18264 themeOf binding,crucial
R12465 T18266 T18265 themeOf NFAT,binding
R12864 T18786 T18787 themeOf Oct-1,binding
R13883 T20251 T20250 themeOf binding,inhibit
R13884 T20257 T20259 themeOf IL-1RA,transcripts
R13885 T20258 T20259 themeOf GAPDH,transcripts
R14752 T21436 T21435 themeOf NFAT,binding
R14753 T21437 T21435 themeOf NFIL-6,binding
R14754 T21451 T21452 themeOf binding,following
R14755 T21453 T21451 themeOf TSST-1,binding
R14756 T21454 T21451 themeOf TSST-1,binding
R14757 T21455 T21451 themeOf TSST-1,binding
R15317 T22350 T22354 themeOf p65,binding
R15318 T22352 T22354 themeOf NFATc2,binding
R15319 T22353 T22354 themeOf c1,binding
R15320 T22359 T22358 themeOf p50,positive
R15321 T22360 T22358 themeOf p65,positive
R15322 T22361 T22358 themeOf NFATc1,positive
R15323 T22362 T22358 themeOf c2,positive
R15324 T22366 T22363 themeOf NFAT c2,positive
R15325 T22367 T22363 themeOf c1,positive
R15624 T22926 T22927 themeOf IL-1β,down-regulated
R15625 T22929 T22927 causeOf TSST-1,down-regulated
R15626 T22930 T22927 causeOf TSST-1,down-regulated
R15627 T22931 T22932 themeOf IL-1β,production
R15628 T22936 T22937 themeOf IL-1β,production
R15629 T22937 T22935 themeOf production,reduction
R15630 T22937 T22938 themeOf production,following
R15631 T22939 T22938 causeOf TSST-1,following
R15632 T22939 T22935 causeOf TSST-1,reduction
R15633 T22940 T22938 causeOf TSST-1,following
R15634 T22940 T22935 causeOf TSST-1,reduction
R15635 T22943 T22944 themeOf IL-1RA,following
R15636 T22945 T22944 causeOf TSST-1,following
R15637 T22946 T22944 causeOf TSST-1,following
R15638 T22947 T22948 themeOf IL-1RA,production
R15639 T22952 T22953 themeOf IL-1RA,production
R16247 T23867 T23869 themeOf TSST-1,binding
R16248 T23869 T23868 themeOf binding,induced
R16249 T23872 T23871 themeOf TSST-1,Binding
R16250 T23873 T23871 themeOf TSST-1,Binding
R16456 T24181 T24182 themeOf TSST-1,binding
R16457 T24186 T24184 themeOf TSST-1,Binding
R16458 T24187 T24184 themeOf TSST-1,Binding
R16459 T24190 T24191 themeOf NFAT,binding
R16867 T24796 T24799 themeOf Decreased,following
R16868 T24797 T24796 themeOf IL-1β,Decreased
R16869 T24798 T24796 themeOf IL-1RA,Decreased
R16870 T24800 T24799 causeOf TSST-1,following
R16871 T24800 T24796 causeOf TSST-1,Decreased
R16872 T24801 T24799 causeOf TSST-1,following
R16873 T24801 T24796 causeOf TSST-1,Decreased
R16874 T24816 T24815 themeOf production,higher
R16875 T24817 T24816 themeOf IL-1RA,production
R16876 T24818 T24816 themeOf IL-1β,production
R17250 T25478 T25480 themeOf NFAT,binding
R17251 T25479 T25480 themeOf NFIL-6,binding
R17252 T25480 T25477 themeOf binding,induced
R17253 T25482 T25480 themeOf promoter,binding
R17254 T25482 T25481 partOf promoter,IL-1RA
R17255 T25484 T25483 themeOf binding,decrease
R17256 T25485 T25488 causeOf Inhibition,resulted
R17257 T25485 T25489 causeOf Inhibition,decreased
R17258 T25486 T25488 causeOf NFAT,resulted
R17259 T25486 T25489 causeOf NFAT,decreased
R17260 T25486 T25485 themeOf NFAT,Inhibition
R17261 T25487 T25489 causeOf NFIL-6,decreased
R17262 T25487 T25485 themeOf NFIL-6,Inhibition
R17263 T25487 T25488 causeOf NFIL-6,resulted
R17264 T25489 T25488 themeOf decreased,resulted
R17265 T25490 T25489 themeOf IL-1RA,decreased
R17266 T25493 T25496 causeOf Inhibition,reduced
R17267 T25494 T25493 themeOf NFAT,Inhibition
R17268 T25494 T25496 causeOf NFAT,reduced
R17269 T25495 T25493 themeOf NFIL-6,Inhibition
R17270 T25495 T25496 causeOf NFIL-6,reduced
R17271 T25497 T25499 themeOf production,following
R17272 T25497 T25496 themeOf production,reduced
R17273 T25498 T25497 themeOf IL-1RA,production
R1869 T3114 T3113 themeOf NFIL-6,Binding
R1870 T3115 T3113 themeOf NFAT,Binding
R1871 T3119 T3116 partOf promoters,TNFα
R1872 T3119 T3113 themeOf promoters,Binding
R1873 T3121 T3120 causeOf TSST-1,following
R1874 T3123 T3122 themeOf NFIL-6,binding
R1875 T3128 T3127 causeOf TSST-1,induced
R1876 T3131 T3130 themeOf binding,induced
R1877 T3132 T3131 themeOf p65,binding
R1878 T3133 T3131 themeOf p50,binding
R1879 T3135 T3134 themeOf p65,binding
R1880 T3139 T3138 themeOf binding,induced
R1881 T3142 T3143 causeOf TSST-1,induced
R1882 T3142 T3144 themeOf TSST-1,binding
R1883 T3143 T3141 themeOf induced,decreased
R1884 T3144 T3143 themeOf binding,induced
R1885 T3144 T3141 themeOf binding,decreased
R1886 T3145 T3144 themeOf TSST-1,binding
R1887 T3150 T3149 themeOf NFAT,binding
R1888 T3154 T3153 themeOf binding,induced
R1889 T3155 T3154 themeOf NFATc2,binding
R1890 T3156 T3154 themeOf NFATc1,binding
R2792 T4610 T4609 themeOf production,lead
R2793 T4611 T4610 themeOf TNFα,production
R2794 T4612 T4610 themeOf IL-8,production
R2795 T4613 T4610 themeOf IL-6,production
R2796 T4614 T4610 themeOf IFNγ,production
R2797 T4616 T4617 themeOf IL-1β,production
R2798 T4617 T4618 themeOf production,following
R2799 T4620 T4621 themeOf IL-1β,production
R2800 T4621 T4619 themeOf production,up-regulation
R2801 T4624 T4623 themeOf IL-1β,reduction
R2802 T4625 T4623 causeOf TSST-1,reduction
R2803 T4628 T4629 causeOf TSST-1,induced
R2804 T4629 T4627 themeOf induced,reduction
R2805 T4630 T4629 themeOf IL-1β,induced
R2806 T4632 T4631 themeOf IL-6,induced
R2807 T4635 T4636 themeOf IL-6,production
R2808 T4636 T4634 themeOf production,induced
R2809 T4638 T4639 themeOf IL-6,production
R2810 T4639 T4637 themeOf production,decreased
R2811 T4644 T4645 themeOf IL-8,production
R2812 T4645 T4643 themeOf production,induced
R2813 T4647 T4646 themeOf increase,resulted
R2814 T4648 T4649 themeOf IL-8,production
R2815 T4649 T4647 themeOf production,increase
R2816 T4650 T4653 themeOf alteration,following
R2817 T4651 T4652 themeOf IL-8,production
R2818 T4652 T4650 themeOf production,alteration
R2819 T4652 T4653 themeOf production,following
R2820 T4654 T4653 causeOf TSST-1,following
R2821 T4654 T4650 causeOf TSST-1,alteration
R2822 T4655 T4653 causeOf TSST-1,following
R2823 T4655 T4650 causeOf TSST-1,alteration
R2824 T4656 T4653 causeOf TSST-1,following
R2825 T4656 T4650 causeOf TSST-1,alteration
R2826 T4657 T4660 themeOf IL-8,following
R2827 T4657 T4659 themeOf IL-8,produced
R2828 T4658 T4660 themeOf IL-1RA,following
R2829 T4658 T4659 themeOf IL-1RA,produced
R2830 T4659 T4660 themeOf produced,following
R2831 T4662 T4663 themeOf IL-1RA,production
R2832 T4663 T4661 themeOf production,alter
R2833 T4664 T4665 causeOf TSST-1,increase
R2834 T4666 T4667 themeOf IL-1RA,production
R2835 T4667 T4665 themeOf production,increase
R2836 T4671 T4672 causeOf TSST-1,induced
R2837 T4672 T4670 themeOf induced,elevated
R2838 T4673 T4672 themeOf IL-1RA,induced
R2839 T4680 T4679 themeOf IL-8,induced
R2840 T4681 T4679 themeOf IL-1RA,induced
R2841 T4683 T4684 themeOf TNFα,production
R2842 T4686 T4687 themeOf TNFα,production
R2843 T4687 T4685 themeOf production,change
R2844 T4691 T4692 themeOf TNFα,secretion
R2845 T4692 T4690 themeOf secretion,effect
R2846 T4693 T4694 themeOf IFNγ,production
R2847 T4694 T4695 themeOf production,following
R2848 T4696 T4699 themeOf increase,following
R2849 T4697 T4698 themeOf IFNγ,production
R2850 T4698 T4700 themeOf production,down-regulation
R2851 T4698 T4696 themeOf production,increase
R2852 T4698 T4699 themeOf production,following
R2853 T4701 T4700 causeOf TSST-1,down-regulation
R2854 T4702 T4700 themeOf TSST-1,down-regulation
R2855 T4703 T4700 causeOf TSST-1,down-regulation
R2856 T4708 T4714 themeOf production,induced
R2857 T4709 T4708 themeOf IL-2,production
R2858 T4710 T4708 themeOf IL-12,production
R2859 T4711 T4708 themeOf IL-4,production
R2860 T4712 T4714 themeOf IL-10,induced
R2861 T4712 T4708 themeOf IL-10,production
R2862 T4713 T4714 themeOf TGFβ 1,induced
R2863 T4713 T4708 themeOf TGFβ 1,production
R5080 T7970 T7972 themeOf NFIL-6,binding
R5081 T7971 T7972 themeOf NFAT,binding
R5082 T7973 T7975 causeOf TSST-1,induced
R5083 T7974 T7975 causeOf TSST-1,induced
R5084 T7976 T7977 themeOf IL-1RA,expression
R5085 T7977 T7975 themeOf expression,induced
R5086 T7979 T7982 themeOf TNFα,bind
R5087 T7980 T7982 themeOf IL-6,bind
R5088 T7980 T7978 themeOf IL-6,induced
R5089 T7981 T7978 themeOf IFNγ,induced
R5090 T7986 T7987 themeOf binding,induced
R5091 T7994 T7995 themeOf TSST-1,binding
R5092 T7994 T7996 themeOf TSST-1,down-regulated
R5093 T7995 T7996 themeOf binding,down-regulated
R5094 T7997 T7998 causeOf TSST-1,induced
R5095 T7999 T7998 themeOf increased,induced
R5096 T8000 T7999 themeOf binding,increased
R5097 T8000 T7998 themeOf binding,induced
R5098 T8001 T8000 themeOf TSST-1,binding
R5099 T8002 T8007 themeOf binding,elevated
R5100 T8002 T8004 themeOf binding,following
R5101 T8003 T8002 themeOf site,binding
R5102 T8005 T8004 causeOf TSST-1,following
R6268 T9525 T9526 causeOf TSST-1,induced
R6269 T9526 T9524 themeOf induced,modulated
R6270 T9527 T9526 themeOf IL-1β,induced
R6271 T9528 T9526 themeOf IL-1RA,induced
R6272 T9542 T9541 themeOf production,higher
R6273 T9543 T9542 themeOf IL-1RA,production
R6274 T9544 T9542 themeOf IL-1β,production
R6275 T9546 T9545 themeOf IL-1,decrease
R6276 T9547 T9550 themeOf dependent,following
R6277 T9547 T9545 themeOf dependent,decrease
R6278 T9548 T9547 themeOf release,dependent
R6279 T9548 T9550 themeOf release,following
R6280 T9549 T9548 themeOf IL-2,release
R6281 T9551 T9550 causeOf TSST-1,following
R6282 T9552 T9550 causeOf TSST-1,following
R6814 T10409 T10408 themeOf IL-1RA,reduced
R6815 T10412 T10411 themeOf IL-1RA,induction
R6816 T10415 T10414 causeOf NFIL-6,via
R6817 T10419 T10418 themeOf binding,down-regulated
R6818 T10422 T10421 themeOf IL-1RA,reduction
R6819 T10423 T10421 themeOf IL-1RA,reduction
R6820 T10425 T10424 themeOf binding,reduction
R6821 T10428 T10427 themeOf IL-1RA,decrease
R6822 T10429 T10427 causeOf inhibition,decrease
R6823 T10434 T10435 themeOf IL-1RA,release
R6824 T10435 T10433 themeOf release,decreased
R41 T136 T135 equivalentTo TSST-1,toxic shock syndrome toxin 1
R42 T138 T137 themeOf NFinterleukin(IL)-6,activation
R43 T139 T137 themeOf NFAT,activation
R44 T140 T137 themeOf TSST-1,activation
R45 T141 T146 themeOf production,induced
R46 T142 T141 themeOf IL-1β,production
R47 T143 T141 themeOf IL-6,production
R48 T144 T141 themeOf tumor necrosis factor α,production
R49 T145 T141 themeOf interferon γ,production
R50 T148 T149 themeOf IL-8,binding
R51 T148 T147 themeOf IL-8,induced
R52 T152 T154 themeOf IL-1receptor antagonist,production
R53 T153 T152 equivalentTo RA,IL-1receptor antagonist
R54 T154 T151 themeOf production,increase
R56 T157 T156 themeOf binding,induced
R57 T161 T162 causeOf TSST-1,induced
R58 T162 T160 themeOf induced,elevated
R59 T163 T162 themeOf binding,induced
R60 T164 T166 causeOf NFIL-6,increase
R61 T164 T163 themeOf NFIL-6,binding
R62 T165 T163 themeOf NFAT,binding
R63 T167 T166 themeOf IL-1RA,increase
R64 T168 T169 causeOf TSST-1,induced
R65 T171 T170 themeOf IL-1β,reduction
R7555 T11707 T11708 causeOf TSST-1,induce
R40 T131 T130 themeOf IL-6,binding