PMC:1448208 / 6119-6532
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4113 | 0-8 | RB | denotes | Recently |
T4114 | 111-120 | VBN | denotes | described |
T4115 | 8-10 | , | denotes | , |
T4116 | 10-11 | DT | denotes | a |
T4117 | 22-33 | NN | denotes | nitrosourea |
T4118 | 12-13 | NN | denotes | N |
T4119 | 14-19 | NN | denotes | ethyl |
T4120 | 13-14 | HYPH | denotes | - |
T4121 | 19-20 | HYPH | denotes | - |
T4122 | 20-21 | NN | denotes | N |
T4123 | 21-22 | HYPH | denotes | - |
T4124 | 40-47 | VBN | denotes | induced |
T4125 | 34-35 | -LRB- | denotes | ( |
T4126 | 35-38 | NN | denotes | ENU |
T4127 | 38-39 | -RRB- | denotes | ) |
T4128 | 39-40 | HYPH | denotes | - |
T4129 | 55-60 | NN | denotes | mouse |
T4130 | 48-54 | NN | denotes | mutant |
T4131 | 61-65 | WDT | denotes | that |
T4132 | 81-90 | VBZ | denotes | resembles |
T4133 | 66-80 | RB | denotes | phenotypically |
T4134 | 91-96 | JJ | denotes | human |
T4135 | 97-101 | NN | denotes | MSUD |
T4136 | 102-105 | VBZ | denotes | has |
T4137 | 106-110 | VBN | denotes | been |
T4138 | 121-122 | -LRB- | denotes | [ |
T4139 | 122-124 | CD | denotes | 20 |
T4140 | 124-125 | -RRB- | denotes | ] |
T4141 | 125-126 | . | denotes | . |
T4142 | 126-295 | sentence | denotes | However, the mutation in this model disrupts a splice site in the mitochondrial branched-chain aminotransferase (BCAT) gene, not in BCKDH, the deficient enzyme in MSUD. |
T4143 | 127-134 | RB | denotes | However |
T4144 | 163-171 | VBZ | denotes | disrupts |
T4145 | 134-136 | , | denotes | , |
T4146 | 136-139 | DT | denotes | the |
T4147 | 140-148 | NN | denotes | mutation |
T4148 | 149-151 | IN | denotes | in |
T4149 | 152-156 | DT | denotes | this |
T4150 | 157-162 | NN | denotes | model |
T4151 | 172-173 | DT | denotes | a |
T4152 | 181-185 | NN | denotes | site |
T4153 | 174-180 | NN | denotes | splice |
T4154 | 186-188 | IN | denotes | in |
T4155 | 189-192 | DT | denotes | the |
T4156 | 222-238 | NN | denotes | aminotransferase |
T4157 | 193-206 | JJ | denotes | mitochondrial |
T4158 | 207-215 | VBN | denotes | branched |
T4159 | 216-221 | NN | denotes | chain |
T4160 | 215-216 | HYPH | denotes | - |
T4161 | 246-250 | NN | denotes | gene |
T4162 | 239-240 | -LRB- | denotes | ( |
T4163 | 240-244 | NN | denotes | BCAT |
T4164 | 244-245 | -RRB- | denotes | ) |
T4165 | 250-252 | , | denotes | , |
T4166 | 252-255 | RB | denotes | not |
T4167 | 256-258 | IN | denotes | in |
T4168 | 259-264 | NN | denotes | BCKDH |
T4169 | 264-266 | , | denotes | , |
T4170 | 266-269 | DT | denotes | the |
T4171 | 280-286 | NN | denotes | enzyme |
T4172 | 270-279 | JJ | denotes | deficient |
T4173 | 287-289 | IN | denotes | in |
T4174 | 290-294 | NN | denotes | MSUD |
T4175 | 294-295 | . | denotes | . |
T4176 | 295-413 | sentence | denotes | Because the mutation is not in BCKDH, the validity of this mutant mouse line for modeling human MSUD is questionable. |
T4177 | 296-303 | IN | denotes | Because |
T4178 | 317-319 | VBZ | denotes | is |
T4179 | 304-307 | DT | denotes | the |
T4180 | 308-316 | NN | denotes | mutation |
T4181 | 397-399 | VBZ | denotes | is |
T4182 | 320-323 | RB | denotes | not |
T4183 | 324-326 | IN | denotes | in |
T4184 | 327-332 | NN | denotes | BCKDH |
T4185 | 332-334 | , | denotes | , |
T4186 | 334-337 | DT | denotes | the |
T4187 | 338-346 | NN | denotes | validity |
T4188 | 347-349 | IN | denotes | of |
T4189 | 350-354 | DT | denotes | this |
T4190 | 368-372 | NN | denotes | line |
T4191 | 355-361 | NN | denotes | mutant |
T4192 | 362-367 | NN | denotes | mouse |
T4193 | 373-376 | IN | denotes | for |
T4194 | 377-385 | VBG | denotes | modeling |
T4195 | 392-396 | NN | denotes | MSUD |
T4196 | 386-391 | JJ | denotes | human |
T4197 | 400-412 | JJ | denotes | questionable |
T4198 | 412-413 | . | denotes | . |
R1065 | T4162 | T4156 | punct | (,aminotransferase |
R1067 | T4163 | T4156 | appos | BCAT,aminotransferase |
R1068 | T4164 | T4161 | punct | ),gene |
R1069 | T4165 | T4154 | punct | ", ",in |
R1070 | T4166 | T4154 | neg | not,in |
R1071 | T4167 | T4154 | prep | in,in |
R1073 | T4168 | T4167 | pobj | BCKDH,in |
R1074 | T4169 | T4168 | punct | ", ",BCKDH |
R1076 | T4170 | T4171 | det | the,enzyme |
R1077 | T4171 | T4168 | appos | enzyme,BCKDH |
R1078 | T4172 | T4171 | amod | deficient,enzyme |
R1079 | T4173 | T4171 | prep | in,enzyme |
R1081 | T4174 | T4173 | pobj | MSUD,in |
R1082 | T4175 | T4144 | punct | .,disrupts |
R1084 | T4177 | T4178 | mark | Because,is |
R1085 | T4178 | T4181 | advcl | is,is |
R1087 | T4179 | T4180 | det | the,mutation |
R1088 | T4180 | T4178 | nsubj | mutation,is |
R1089 | T4182 | T4178 | neg | not,is |
R1091 | T4183 | T4178 | prep | in,is |
R1092 | T4184 | T4183 | pobj | BCKDH,in |
R1093 | T4185 | T4181 | punct | ", ",is |
R1094 | T4186 | T4187 | det | the,validity |
R1095 | T4187 | T4181 | nsubj | validity,is |
R1097 | T4188 | T4187 | prep | of,validity |
R1098 | T4189 | T4190 | det | this,line |
R1099 | T4190 | T4188 | pobj | line,of |
R1100 | T4191 | T4190 | compound | mutant,line |
R1102 | T4192 | T4190 | compound | mouse,line |
R1103 | T4193 | T4187 | prep | for,validity |
R1104 | T4194 | T4195 | amod | modeling,MSUD |
R1106 | T4195 | T4193 | pobj | MSUD,for |
R1107 | T4196 | T4195 | amod | human,MSUD |
R1108 | T4197 | T4181 | acomp | questionable,is |
R1110 | T4198 | T4181 | punct | .,is |
R1212 | T4113 | T4114 | advmod | Recently,described |
R1217 | T4115 | T4114 | punct | ", ",described |
R1222 | T4116 | T4117 | det | a,nitrosourea |
R1227 | T4117 | T4124 | npadvmod | nitrosourea,induced |
R1231 | T4118 | T4119 | compound | N,ethyl |
R1235 | T4119 | T4117 | compound | ethyl,nitrosourea |
R1239 | T4120 | T4119 | punct | -,ethyl |
R1243 | T4121 | T4117 | punct | -,nitrosourea |
R1247 | T4122 | T4117 | compound | N,nitrosourea |
R1252 | T4123 | T4117 | punct | -,nitrosourea |
R1256 | T4124 | T4129 | amod | induced,mouse |
R1258 | T4125 | T4117 | punct | (,nitrosourea |
R1259 | T4126 | T4117 | appos | ENU,nitrosourea |
R1260 | T4127 | T4124 | punct | ),induced |
R1261 | T4128 | T4124 | punct | -,induced |
R1262 | T4129 | T4114 | nsubjpass | mouse,described |
R1263 | T4130 | T4129 | compound | mutant,mouse |
R1264 | T4131 | T4132 | dep | that,resembles |
R1265 | T4132 | T4129 | relcl | resembles,mouse |
R1266 | T4133 | T4132 | advmod | phenotypically,resembles |
R1267 | T4134 | T4135 | amod | human,MSUD |
R1268 | T4135 | T4132 | dobj | MSUD,resembles |
R1269 | T4136 | T4114 | aux | has,described |
R1270 | T4137 | T4114 | auxpass | been,described |
R1271 | T4138 | T4139 | punct | [,20 |
R1272 | T4139 | T4114 | parataxis | 20,described |
R1273 | T4140 | T4139 | punct | ],20 |
R1274 | T4141 | T4114 | punct | .,described |
R1275 | T4143 | T4144 | advmod | However,disrupts |
R1276 | T4145 | T4144 | punct | ", ",disrupts |
R1277 | T4146 | T4147 | det | the,mutation |
R1278 | T4147 | T4144 | nsubj | mutation,disrupts |
R1279 | T4148 | T4147 | prep | in,mutation |
R1280 | T4149 | T4150 | det | this,model |
R1281 | T4150 | T4148 | pobj | model,in |
R1282 | T4151 | T4152 | det | a,site |
R1283 | T4152 | T4144 | dobj | site,disrupts |
R1284 | T4153 | T4152 | compound | splice,site |
R1285 | T4154 | T4152 | prep | in,site |
R1286 | T4155 | T4156 | det | the,aminotransferase |
R1287 | T4156 | T4161 | nmod | aminotransferase,gene |
R1288 | T4157 | T4156 | amod | mitochondrial,aminotransferase |
R1289 | T4158 | T4159 | amod | branched,chain |
R1290 | T4159 | T4156 | nmod | chain,aminotransferase |
R1291 | T4160 | T4159 | punct | -,chain |
R1292 | T4161 | T4154 | pobj | gene,in |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3268 | 12-33 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T3269 | 35-38 | CHEBI:23995 | denotes | ENU |
T3270 | 48-54 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T3271 | 55-60 | NCBITaxon:10088 | denotes | mouse |
T3272 | 91-96 | NCBITaxon:9606 | denotes | human |
T3273 | 140-148 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T3274 | 174-180 | GO:0008380 | denotes | splice |
T3275 | 174-185 | SO_EXT:0000162 | denotes | splice site |
T3276 | 193-206 | GO:0005739 | denotes | mitochondrial |
T3277 | 193-238 | PR_EXT:000004683 | denotes | mitochondrial branched-chain aminotransferase |
T3278 | 207-238 | GO_PR_EXT:branched_chain_amino_acid_aminotransferase | denotes | branched-chain aminotransferase |
T3279 | 240-244 | GO_PR_EXT:branched_chain_amino_acid_aminotransferase | denotes | BCAT |
T3280 | 246-250 | SO_EXT:0000704 | denotes | gene |
T3281 | 280-286 | CHEBI_GO_SO_EXT:enzyme | denotes | enzyme |
T3282 | 308-316 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T3283 | 355-361 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T3284 | 362-367 | NCBITaxon:10088 | denotes | mouse |
T3285 | 386-391 | NCBITaxon:9606 | denotes | human |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3157 | 12-33 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T3158 | 35-38 | CHEBI:23995 | denotes | ENU |
T3159 | 55-60 | NCBITaxon:10088 | denotes | mouse |
T3160 | 91-96 | NCBITaxon:9606 | denotes | human |
T3161 | 174-180 | GO:0008380 | denotes | splice |
T3162 | 174-185 | SO:0000162 | denotes | splice site |
T3163 | 193-206 | GO:0005739 | denotes | mitochondrial |
T3164 | 193-238 | PR:000004683 | denotes | mitochondrial branched-chain aminotransferase |
T3165 | 246-250 | SO:0000704 | denotes | gene |
T3166 | 362-367 | NCBITaxon:10088 | denotes | mouse |
T3167 | 386-391 | NCBITaxon:9606 | denotes | human |