Id |
Subject |
Object |
Predicate |
Lexical cue |
T3997 |
0-7 |
IN |
denotes |
Because |
T3998 |
79-81 |
VBZ |
denotes |
is |
T3999 |
8-10 |
IN |
denotes |
of |
T4000 |
11-14 |
DT |
denotes |
the |
T4001 |
38-45 |
NNS |
denotes |
options |
T4002 |
15-22 |
JJ |
denotes |
current |
T4003 |
23-37 |
JJ |
denotes |
unsatisfactory |
T4004 |
46-49 |
IN |
denotes |
for |
T4005 |
50-53 |
DT |
denotes |
the |
T4006 |
54-63 |
NN |
denotes |
treatment |
T4007 |
64-66 |
IN |
denotes |
of |
T4008 |
67-71 |
NN |
denotes |
MSUD |
T4009 |
71-73 |
, |
denotes |
, |
T4010 |
73-78 |
EX |
denotes |
there |
T4011 |
82-83 |
DT |
denotes |
a |
T4012 |
84-88 |
NN |
denotes |
need |
T4013 |
89-92 |
IN |
denotes |
for |
T4014 |
93-101 |
VBN |
denotes |
improved |
T4015 |
102-111 |
NNS |
denotes |
therapies |
T4016 |
112-114 |
TO |
denotes |
to |
T4017 |
115-121 |
VB |
denotes |
combat |
T4018 |
122-126 |
DT |
denotes |
this |
T4019 |
127-134 |
NN |
denotes |
disease |
T4020 |
134-135 |
. |
denotes |
. |
T4021 |
135-274 |
sentence |
denotes |
An obstacle to developing novel treatments for MSUD has been the lack of a suitable animal model to perform necessary preclinical studies. |
T4022 |
136-138 |
DT |
denotes |
An |
T4023 |
139-147 |
NN |
denotes |
obstacle |
T4024 |
192-196 |
VBN |
denotes |
been |
T4025 |
148-150 |
IN |
denotes |
to |
T4026 |
151-161 |
VBG |
denotes |
developing |
T4027 |
162-167 |
JJ |
denotes |
novel |
T4028 |
168-178 |
NNS |
denotes |
treatments |
T4029 |
179-182 |
IN |
denotes |
for |
T4030 |
183-187 |
NN |
denotes |
MSUD |
T4031 |
188-191 |
VBZ |
denotes |
has |
T4032 |
197-200 |
DT |
denotes |
the |
T4033 |
201-205 |
NN |
denotes |
lack |
T4034 |
206-208 |
IN |
denotes |
of |
T4035 |
209-210 |
DT |
denotes |
a |
T4036 |
227-232 |
NN |
denotes |
model |
T4037 |
211-219 |
JJ |
denotes |
suitable |
T4038 |
220-226 |
NN |
denotes |
animal |
T4039 |
233-235 |
TO |
denotes |
to |
T4040 |
236-243 |
VB |
denotes |
perform |
T4041 |
244-253 |
JJ |
denotes |
necessary |
T4042 |
266-273 |
NNS |
denotes |
studies |
T4043 |
254-265 |
JJ |
denotes |
preclinical |
T4044 |
273-274 |
. |
denotes |
. |
T4045 |
274-429 |
sentence |
denotes |
Although a Hereford calf model with MSUD has been described [17-19], this model is neither readily available nor practical to perform preclinical studies. |
T4046 |
275-283 |
IN |
denotes |
Although |
T4047 |
325-334 |
VBN |
denotes |
described |
T4048 |
284-285 |
DT |
denotes |
a |
T4049 |
300-305 |
NN |
denotes |
model |
T4050 |
286-294 |
NNP |
denotes |
Hereford |
T4051 |
295-299 |
NN |
denotes |
calf |
T4052 |
306-310 |
IN |
denotes |
with |
T4053 |
311-315 |
NN |
denotes |
MSUD |
T4054 |
316-319 |
VBZ |
denotes |
has |
T4055 |
320-324 |
VBN |
denotes |
been |
T4056 |
355-357 |
VBZ |
denotes |
is |
T4057 |
335-336 |
-LRB- |
denotes |
[ |
T4058 |
336-338 |
CD |
denotes |
17 |
T4059 |
338-339 |
SYM |
denotes |
- |
T4060 |
339-341 |
CD |
denotes |
19 |
T4061 |
341-342 |
-RRB- |
denotes |
] |
T4062 |
342-344 |
, |
denotes |
, |
T4063 |
344-348 |
DT |
denotes |
this |
T4064 |
349-354 |
NN |
denotes |
model |
T4065 |
358-365 |
CC |
denotes |
neither |
T4066 |
374-383 |
JJ |
denotes |
available |
T4067 |
366-373 |
RB |
denotes |
readily |
T4068 |
384-387 |
CC |
denotes |
nor |
T4069 |
388-397 |
JJ |
denotes |
practical |
T4070 |
398-400 |
TO |
denotes |
to |
T4071 |
401-408 |
VB |
denotes |
perform |
T4072 |
409-420 |
JJ |
denotes |
preclinical |
T4073 |
421-428 |
NNS |
denotes |
studies |
T4074 |
428-429 |
. |
denotes |
. |
T4075 |
429-619 |
sentence |
denotes |
Furthermore, comparison of this animal model with human MSUD has shown some differences in the pathology of the disease [1], making this animal a less desirable model for the human disease. |
T4076 |
430-441 |
RB |
denotes |
Furthermore |
T4077 |
495-500 |
VBN |
denotes |
shown |
T4078 |
441-443 |
, |
denotes |
, |
T4079 |
443-453 |
NN |
denotes |
comparison |
T4080 |
454-456 |
IN |
denotes |
of |
T4081 |
457-461 |
DT |
denotes |
this |
T4082 |
469-474 |
NN |
denotes |
model |
T4083 |
462-468 |
NN |
denotes |
animal |
T4084 |
475-479 |
IN |
denotes |
with |
T4085 |
480-485 |
JJ |
denotes |
human |
T4086 |
486-490 |
NN |
denotes |
MSUD |
T4087 |
491-494 |
VBZ |
denotes |
has |
T4088 |
501-505 |
DT |
denotes |
some |
T4089 |
506-517 |
NNS |
denotes |
differences |
T4090 |
518-520 |
IN |
denotes |
in |
T4091 |
521-524 |
DT |
denotes |
the |
T4092 |
525-534 |
NN |
denotes |
pathology |
T4093 |
535-537 |
IN |
denotes |
of |
T4094 |
538-541 |
DT |
denotes |
the |
T4095 |
542-549 |
NN |
denotes |
disease |
T4096 |
550-551 |
-LRB- |
denotes |
[ |
T4097 |
551-552 |
CD |
denotes |
1 |
T4098 |
552-553 |
-RRB- |
denotes |
] |
T4099 |
553-555 |
, |
denotes |
, |
T4100 |
555-561 |
VBG |
denotes |
making |
T4101 |
562-566 |
DT |
denotes |
this |
T4102 |
567-573 |
NN |
denotes |
animal |
T4103 |
591-596 |
NN |
denotes |
model |
T4104 |
574-575 |
DT |
denotes |
a |
T4105 |
576-580 |
RBR |
denotes |
less |
T4106 |
581-590 |
JJ |
denotes |
desirable |
T4107 |
597-600 |
IN |
denotes |
for |
T4108 |
601-604 |
DT |
denotes |
the |
T4109 |
611-618 |
NN |
denotes |
disease |
T4110 |
605-610 |
JJ |
denotes |
human |
T4111 |
618-619 |
. |
denotes |
. |
R990 |
T3999 |
T3997 |
pcomp |
of,Because |
R992 |
T4000 |
T4001 |
det |
the,options |
R995 |
T4002 |
T4001 |
amod |
current,options |
R996 |
T4003 |
T4001 |
amod |
unsatisfactory,options |
R997 |
T4004 |
T4001 |
prep |
for,options |
R998 |
T4005 |
T4006 |
det |
the,treatment |
R1000 |
T4006 |
T4004 |
pobj |
treatment,for |
R1001 |
T4007 |
T4006 |
prep |
of,treatment |
R1003 |
T4008 |
T4007 |
pobj |
MSUD,of |
R1004 |
T4009 |
T3998 |
punct |
", ",is |
R1005 |
T4010 |
T3998 |
expl |
there,is |
R1007 |
T4011 |
T4012 |
det |
a,need |
R1008 |
T4012 |
T3998 |
attr |
need,is |
R1009 |
T4013 |
T4012 |
prep |
for,need |
R1010 |
T4014 |
T4015 |
amod |
improved,therapies |
R1012 |
T4015 |
T4013 |
pobj |
therapies,for |
R1013 |
T4016 |
T4017 |
aux |
to,combat |
R1015 |
T4017 |
T4015 |
advcl |
combat,therapies |
R1016 |
T4018 |
T4019 |
det |
this,disease |
R1017 |
T4019 |
T4017 |
dobj |
disease,combat |
R1018 |
T4020 |
T3998 |
punct |
.,is |
R1020 |
T4022 |
T4023 |
det |
An,obstacle |
R1021 |
T4023 |
T4024 |
nsubj |
obstacle,been |
R1022 |
T4025 |
T4023 |
prep |
to,obstacle |
R1023 |
T4057 |
T4058 |
punct |
[,17 |
R1024 |
T4026 |
T4025 |
pcomp |
developing,to |
R1025 |
T4027 |
T4028 |
amod |
novel,treatments |
R1026 |
T4028 |
T4026 |
dobj |
treatments,developing |
R1027 |
T4029 |
T4028 |
prep |
for,treatments |
R1028 |
T4030 |
T4029 |
pobj |
MSUD,for |
R1029 |
T4031 |
T4024 |
aux |
has,been |
R1030 |
T4058 |
T4047 |
parataxis |
17,described |
R1031 |
T4032 |
T4033 |
det |
the,lack |
R1032 |
T4033 |
T4024 |
attr |
lack,been |
R1033 |
T4034 |
T4033 |
prep |
of,lack |
R1034 |
T4059 |
T4060 |
punct |
-,19 |
R1035 |
T4035 |
T4036 |
det |
a,model |
R1036 |
T4036 |
T4034 |
pobj |
model,of |
R1037 |
T4037 |
T4036 |
amod |
suitable,model |
R1038 |
T4038 |
T4036 |
compound |
animal,model |
R1039 |
T4060 |
T4058 |
prep |
19,17 |
R1040 |
T4039 |
T4040 |
aux |
to,perform |
R1041 |
T4040 |
T4036 |
advcl |
perform,model |
R1042 |
T4041 |
T4042 |
amod |
necessary,studies |
R1043 |
T4061 |
T4058 |
punct |
],17 |
R1044 |
T4042 |
T4040 |
dobj |
studies,perform |
R1045 |
T4043 |
T4042 |
amod |
preclinical,studies |
R1046 |
T4044 |
T4024 |
punct |
.,been |
R1047 |
T4062 |
T4056 |
punct |
", ",is |
R1048 |
T4046 |
T4047 |
mark |
Although,described |
R1049 |
T4047 |
T4056 |
advcl |
described,is |
R1050 |
T4063 |
T4064 |
det |
this,model |
R1051 |
T4048 |
T4049 |
det |
a,model |
R1052 |
T4049 |
T4047 |
nsubjpass |
model,described |
R1053 |
T4050 |
T4051 |
compound |
Hereford,calf |
R1054 |
T4064 |
T4056 |
nsubj |
model,is |
R1055 |
T4051 |
T4049 |
compound |
calf,model |
R1056 |
T4052 |
T4049 |
prep |
with,model |
R1057 |
T4053 |
T4052 |
pobj |
MSUD,with |
R1058 |
T4065 |
T4066 |
preconj |
neither,available |
R1059 |
T4054 |
T4047 |
aux |
has,described |
R1060 |
T4055 |
T4047 |
auxpass |
been,described |
R1061 |
T4066 |
T4056 |
acomp |
available,is |
R1062 |
T4067 |
T4066 |
advmod |
readily,available |
R1063 |
T4068 |
T4066 |
cc |
nor,available |
R1064 |
T4069 |
T4066 |
conj |
practical,available |
R1066 |
T4070 |
T4071 |
aux |
to,perform |
R1072 |
T4071 |
T4069 |
xcomp |
perform,practical |
R1075 |
T4072 |
T4073 |
amod |
preclinical,studies |
R1080 |
T4073 |
T4071 |
dobj |
studies,perform |
R1083 |
T4074 |
T4056 |
punct |
.,is |
R1086 |
T4076 |
T4077 |
advmod |
Furthermore,shown |
R1090 |
T4078 |
T4077 |
punct |
", ",shown |
R1096 |
T4079 |
T4077 |
nsubj |
comparison,shown |
R1101 |
T4080 |
T4079 |
prep |
of,comparison |
R1105 |
T4081 |
T4082 |
det |
this,model |
R1109 |
T4082 |
T4080 |
pobj |
model,of |
R1112 |
T4083 |
T4082 |
compound |
animal,model |
R1115 |
T4084 |
T4082 |
prep |
with,model |
R1119 |
T4085 |
T4086 |
amod |
human,MSUD |
R1126 |
T4086 |
T4084 |
pobj |
MSUD,with |
R1129 |
T4087 |
T4077 |
aux |
has,shown |
R1133 |
T4088 |
T4089 |
det |
some,differences |
R1138 |
T4089 |
T4077 |
dobj |
differences,shown |
R1142 |
T4090 |
T4089 |
prep |
in,differences |
R1145 |
T4091 |
T4092 |
det |
the,pathology |
R1149 |
T4092 |
T4090 |
pobj |
pathology,in |
R1152 |
T4093 |
T4092 |
prep |
of,pathology |
R1155 |
T4094 |
T4095 |
det |
the,disease |
R1158 |
T4095 |
T4093 |
pobj |
disease,of |
R1162 |
T4096 |
T4097 |
punct |
[,1 |
R1163 |
T4097 |
T4077 |
parataxis |
1,shown |
R1165 |
T4098 |
T4097 |
punct |
],1 |
R1168 |
T4099 |
T4077 |
punct |
", ",shown |
R1172 |
T4100 |
T4077 |
advcl |
making,shown |
R1178 |
T4101 |
T4102 |
det |
this,animal |
R1181 |
T4102 |
T4103 |
nsubj |
animal,model |
R1185 |
T4103 |
T4100 |
ccomp |
model,making |
R1188 |
T4104 |
T4103 |
det |
a,model |
R1191 |
T4105 |
T4106 |
advmod |
less,desirable |
R1195 |
T4106 |
T4103 |
amod |
desirable,model |
R1198 |
T4107 |
T4103 |
prep |
for,model |
R1199 |
T4108 |
T4109 |
det |
the,disease |
R1202 |
T4109 |
T4107 |
pobj |
disease,for |
R1205 |
T4110 |
T4109 |
amod |
human,disease |
R1209 |
T4111 |
T4077 |
punct |
.,shown |
R988 |
T3997 |
T3998 |
prep |
Because,is |
R993 |
T4001 |
T3997 |
pobj |
options,Because |