PMC:1448208 / 4407-4848
Annnotations
craft-sa-dev
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management of MSUD patients relies on a strict lifelong dietary restriction of protein or BCAA [1,8]. Such a dietary management of the disease, however, is not entirely satisfactory especially in times of metabolic decompensation due to infection, injuries and other stressors. In spite of dietary intervention, there is significant mortality associated with MSUD and there is a high incidence of mental retardation in survivors [9]."}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T3248","span":{"begin":87,"end":94},"obj":"CHEBI_PR_EXT:protein"},{"id":"T3249","span":{"begin":98,"end":102},"obj":"CHEBI:22918"},{"id":"T3250","span":{"begin":213,"end":222},"obj":"GO:0008152"}],"text":"Current management of MSUD patients relies on a strict lifelong dietary restriction of protein or BCAA [1,8]. Such a dietary management of the disease, however, is not entirely satisfactory especially in times of metabolic decompensation due to infection, injuries and other stressors. In spite of dietary intervention, there is significant mortality associated with MSUD and there is a high incidence of mental retardation in survivors [9]."}
craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T3140","span":{"begin":98,"end":102},"obj":"CHEBI:22918"},{"id":"T3141","span":{"begin":213,"end":222},"obj":"GO:0008152"}],"text":"Current management of MSUD patients relies on a strict lifelong dietary restriction of protein or BCAA [1,8]. Such a dietary management of the disease, however, is not entirely satisfactory especially in times of metabolic decompensation due to infection, injuries and other stressors. In spite of dietary intervention, there is significant mortality associated with MSUD and there is a high incidence of mental retardation in survivors [9]."}