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PMC:1448208 / 3220-3875 JSONTXT

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Id Subject Object Predicate Lexical cue
T3530 22-25 VBP denotes are
T3534 0-3 DT denotes the
T3535 15-21 NNS denotes levels
T3536 4-9 NN denotes blood
T3537 10-14 NN denotes BCAA
T3538 26-32 JJ denotes normal
T3539 33-34 -LRB- denotes [
T3540 34-35 CD denotes 1
T3541 35-36 -RRB- denotes ]
T3542 36-37 . denotes .
T3543 37-236 sentence denotes The overall incidence of MSUD in the general population is 1:185,000 [1], and in certain population groups, such as Mennonites of Pennsylvania, the incidence is estimated to be as high as 1:176 [2].
T3544 38-41 DT denotes The
T3545 50-59 NN denotes incidence
T3546 42-49 JJ denotes overall
T3547 94-96 VBZ denotes is
T3548 60-62 IN denotes of
T3549 63-67 NN denotes MSUD
T3550 68-70 IN denotes in
T3551 71-74 DT denotes the
T3552 83-93 NN denotes population
T3553 75-82 JJ denotes general
T3554 97-98 CD denotes 1
T3555 99-106 CD denotes 185,000
T3556 98-99 SYM denotes :
T3557 107-108 -LRB- denotes [
T3558 108-109 CD denotes 1
T3559 109-110 -RRB- denotes ]
T3560 110-112 , denotes ,
T3561 112-115 CC denotes and
T3562 116-118 IN denotes in
T3563 199-208 VBN denotes estimated
T3564 119-126 JJ denotes certain
T3565 138-144 NNS denotes groups
T3566 127-137 NN denotes population
T3567 144-146 , denotes ,
T3568 146-150 JJ denotes such
T3569 151-153 IN denotes as
T3570 154-164 NNS denotes Mennonites
T3571 165-167 IN denotes of
T3572 168-180 NNP denotes Pennsylvania
T3573 180-182 , denotes ,
T3574 182-185 DT denotes the
T3575 186-195 NN denotes incidence
T3576 196-198 VBZ denotes is
T3577 209-211 TO denotes to
T3578 212-214 VB denotes be
T3579 215-217 IN denotes as
T3580 218-222 JJ denotes high
T3581 223-225 IN denotes as
T3582 226-227 CD denotes 1
T3583 228-231 CD denotes 176
T3584 227-228 SYM denotes :
T3585 232-233 -LRB- denotes [
T3586 233-234 CD denotes 2
T3587 234-235 -RRB- denotes ]
T3588 235-236 . denotes .
T3589 236-420 sentence denotes The BCKDH complex, the deficient enzyme in MSUD, consists of three catalytic proteins, a decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoyl dehydrogenase (E3).
T3590 237-240 DT denotes The
T3591 247-254 NN denotes complex
T3592 241-246 NN denotes BCKDH
T3593 286-294 VBZ denotes consists
T3594 254-256 , denotes ,
T3595 256-259 DT denotes the
T3596 270-276 NN denotes enzyme
T3597 260-269 JJ denotes deficient
T3598 277-279 IN denotes in
T3599 280-284 NN denotes MSUD
T3600 284-286 , denotes ,
T3601 295-297 IN denotes of
T3602 298-303 CD denotes three
T3603 314-322 NN denotes proteins
T3604 304-313 JJ denotes catalytic
T3605 322-324 , denotes ,
T3606 324-325 DT denotes a
T3607 326-339 NN denotes decarboxylase
T3608 340-341 -LRB- denotes (
T3609 341-343 NN denotes E1
T3610 343-344 -RRB- denotes )
T3611 344-346 , denotes ,
T3612 346-347 DT denotes a
T3613 362-374 NN denotes transacylase
T3614 348-361 NN denotes dihydrolipoyl
T3615 375-376 -LRB- denotes (
T3616 376-378 NN denotes E2
T3617 378-379 -RRB- denotes )
T3618 379-381 , denotes ,
T3619 381-384 CC denotes and
T3620 385-386 DT denotes a
T3621 401-414 NN denotes dehydrogenase
T3622 387-400 NN denotes dihydrolipoyl
T3623 415-416 -LRB- denotes (
T3624 416-418 NN denotes E3
T3625 418-419 -RRB- denotes )
T3626 419-420 . denotes .
T3627 420-499 sentence denotes The E1 component is a heterotetramer composed of two α and two β subunits [3].
T3628 421-424 DT denotes The
T3629 428-437 NN denotes component
T3630 425-427 NN denotes E1
T3631 438-440 VBZ denotes is
T3632 441-442 DT denotes a
T3633 443-457 NN denotes heterotetramer
T3634 458-466 VBN denotes composed
T3635 467-469 IN denotes of
T3636 470-473 CD denotes two
T3637 474-475 NN denotes α
T3638 486-494 NNS denotes subunits
T3639 476-479 CC denotes and
T3640 480-483 CD denotes two
T3641 484-485 NN denotes β
T3642 495-496 -LRB- denotes [
T3643 496-497 CD denotes 3
T3644 497-498 -RRB- denotes ]
T3645 498-499 . denotes .
T3647 500-503 DT denotes The
T3648 514-524 NNS denotes components
T3649 504-506 NN denotes E1
T3650 507-510 CC denotes and
T3651 511-513 NN denotes E2
T3652 525-528 VBP denotes are
T3653 529-537 JJ denotes specific
T3654 538-540 IN denotes to
T3655 541-546 NN denotes BCKDH
T3656 546-548 , denotes ,
T3657 548-555 IN denotes whereas
T3658 567-571 VBN denotes used
T3659 556-558 NN denotes E3
T3660 559-561 VBZ denotes is
T3661 562-566 RB denotes also
T3662 572-574 IN denotes by
T3663 575-583 NN denotes pyruvate
T3664 618-627 NNS denotes complexes
T3665 584-587 CC denotes and
T3666 588-589 NN denotes α
T3667 590-603 NN denotes ketoglutarate
T3668 589-590 HYPH denotes -
T3669 604-617 NN denotes dehydrogenase
T3670 628-629 -LRB- denotes [
T3671 629-630 CD denotes 3
T3672 630-631 -RRB- denotes ]
T3673 632-635 CC denotes and
T3674 636-639 DT denotes the
T3676 640-647 NN denotes glycine
R523 T3534 T3535 det the,levels
R524 T3535 T3530 nsubj levels,are
R526 T3536 T3535 compound blood,levels
R527 T3537 T3535 compound BCAA,levels
R528 T3538 T3530 acomp normal,are
R530 T3539 T3540 punct [,1
R531 T3540 T3530 parataxis 1,are
R533 T3541 T3540 punct ],1
R534 T3542 T3530 punct .,are
R536 T3544 T3545 det The,incidence
R537 T3545 T3547 nsubj incidence,is
R538 T3546 T3545 amod overall,incidence
R540 T3548 T3545 prep of,incidence
R542 T3549 T3548 pobj MSUD,of
R543 T3550 T3545 prep in,incidence
R544 T3551 T3552 det the,population
R545 T3552 T3550 pobj population,in
R546 T3553 T3552 amod general,population
R548 T3554 T3555 nummod 1,"185,000"
R549 T3555 T3547 attr "185,000",is
R550 T3556 T3555 punct :,"185,000"
R552 T3557 T3558 punct [,1
R553 T3558 T3547 parataxis 1,is
R554 T3559 T3558 punct ],1
R556 T3560 T3547 punct ", ",is
R557 T3561 T3547 cc and,is
R558 T3562 T3563 prep in,estimated
R560 T3563 T3547 conj estimated,is
R562 T3564 T3565 amod certain,groups
R563 T3565 T3562 pobj groups,in
R564 T3566 T3565 compound population,groups
R566 T3567 T3565 punct ", ",groups
R567 T3568 T3569 amod such,as
R568 T3569 T3565 prep as,groups
R569 T3570 T3569 pobj Mennonites,as
R571 T3571 T3570 prep of,Mennonites
R572 T3572 T3571 pobj Pennsylvania,of
R574 T3573 T3563 punct ", ",estimated
R575 T3574 T3575 det the,incidence
R576 T3575 T3563 nsubjpass incidence,estimated
R577 T3576 T3563 auxpass is,estimated
R579 T3577 T3578 aux to,be
R580 T3578 T3563 xcomp be,estimated
R582 T3579 T3578 prep as,be
R583 T3580 T3579 amod high,as
R584 T3581 T3580 prep as,high
R586 T3582 T3583 nummod 1,176
R587 T3583 T3581 pobj 176,as
R588 T3584 T3583 punct :,176
R590 T3585 T3586 punct [,2
R591 T3586 T3563 parataxis 2,estimated
R592 T3587 T3586 punct ],2
R593 T3588 T3563 punct .,estimated
R595 T3590 T3591 det The,complex
R597 T3591 T3593 nsubj complex,consists
R598 T3592 T3591 compound BCKDH,complex
R599 T3594 T3591 punct ", ",complex
R600 T3595 T3596 det the,enzyme
R601 T3596 T3591 appos enzyme,complex
R603 T3597 T3596 amod deficient,enzyme
R604 T3598 T3596 prep in,enzyme
R605 T3599 T3598 pobj MSUD,in
R606 T3600 T3593 punct ", ",consists
R607 T3601 T3593 prep of,consists
R609 T3602 T3603 nummod three,proteins
R610 T3603 T3601 pobj proteins,of
R611 T3604 T3603 amod catalytic,proteins
R613 T3605 T3603 punct ", ",proteins
R614 T3606 T3607 det a,decarboxylase
R615 T3607 T3603 appos decarboxylase,proteins
R617 T3608 T3609 punct (,E1
R618 T3609 T3607 parataxis E1,decarboxylase
R619 T3610 T3609 punct ),E1
R621 T3611 T3607 punct ", ",decarboxylase
R622 T3612 T3613 det a,transacylase
R624 T3613 T3607 conj transacylase,decarboxylase
R625 T3614 T3613 compound dihydrolipoyl,transacylase
R626 T3615 T3616 punct (,E2
R628 T3616 T3613 parataxis E2,transacylase
R629 T3617 T3616 punct ),E2
R630 T3618 T3613 punct ", ",transacylase
R632 T3619 T3613 cc and,transacylase
R633 T3620 T3621 det a,dehydrogenase
R634 T3621 T3613 conj dehydrogenase,transacylase
R635 T3622 T3621 compound dihydrolipoyl,dehydrogenase
R637 T3623 T3624 punct (,E3
R638 T3624 T3621 parataxis E3,dehydrogenase
R639 T3625 T3624 punct ),E3
R641 T3626 T3593 punct .,consists
R644 T3629 T3631 nsubj component,is
R645 T3630 T3629 compound E1,component
R647 T3632 T3633 det a,heterotetramer
R648 T3633 T3631 attr heterotetramer,is
R651 T3634 T3633 acl composed,heterotetramer
R653 T3635 T3634 prep of,composed
R654 T3636 T3637 nummod two,α
R655 T3637 T3638 nmod α,subunits
R657 T3638 T3635 pobj subunits,of
R658 T3639 T3637 cc and,α
R660 T3640 T3641 nummod two,β
R661 T3641 T3637 conj β,α
R662 T3642 T3643 punct [,3
R664 T3643 T3631 parataxis 3,is
R665 T3644 T3643 punct ],3
R666 T3645 T3631 punct .,is
R668 T3647 T3648 det The,components
R670 T3648 T3652 nsubj components,are
R671 T3649 T3648 nmod E1,components
R672 T3650 T3649 cc and,E1
R674 T3651 T3649 conj E2,E1
R675 T3653 T3652 acomp specific,are
R676 T3654 T3653 prep to,specific
R677 T3655 T3654 pobj BCKDH,to
R679 T3656 T3652 punct ", ",are
R680 T3657 T3658 mark whereas,used
R681 T3658 T3652 advcl used,are
R683 T3659 T3658 nsubjpass E3,used
R684 T3660 T3658 auxpass is,used
R685 T3661 T3658 advmod also,used
R687 T3662 T3658 agent by,used
R688 T3663 T3664 nmod pyruvate,complexes
R689 T3664 T3662 pobj complexes,by
R691 T3665 T3663 cc and,pyruvate
R692 T3666 T3667 compound α,ketoglutarate
R694 T3667 T3663 conj ketoglutarate,pyruvate
R695 T3668 T3667 punct -,ketoglutarate
R696 T3669 T3664 compound dehydrogenase,complexes
R697 T3670 T3671 punct [,3
R698 T3671 T3664 parataxis 3,complexes
R700 T3672 T3671 punct ],3
R701 T3673 T3664 cc and,complexes
R643 T3628 T3629 det The,component

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3202 4-9 UBERON:0000178 denotes blood
T3203 10-14 CHEBI:22918 denotes BCAA
T3204 241-254 GO:0017086 denotes BCKDH complex
T3205 270-276 CHEBI_GO_SO_EXT:enzyme denotes enzyme
T3206 304-313 GO_MOP_EXT:catalysis denotes catalytic
T3207 314-322 CHEBI_PR_EXT:protein denotes proteins
T3208 326-339 GO_EXT:0016831 denotes decarboxylase
T3209 348-361 CHEBI:50488 denotes dihydrolipoyl
T3210 348-374 GO_PR_EXT:dihydrolipoyllysine_residue_2_methylpropanoyl_transferase denotes dihydrolipoyl transacylase
T3211 376-378 PR_EXT:000006300 denotes E2
T3212 387-400 CHEBI:50488 denotes dihydrolipoyl
T3213 387-414 GO_PR_EXT:dihydrolipoamide_dehydrogenase denotes dihydrolipoyl dehydrogenase
T3214 416-418 PR_EXT:000006506 denotes E3
T3215 449-457 GO_EXT:tetrameric_macromolecular_complex denotes tetramer
T3216 474-475 _FRAGMENT denotes α
T3217 486-494 PR_EXT:000004686 denotes subunits
T3218 484-494 PR_EXT:000004687 denotes β subunits
T3219 511-513 PR_EXT:000006300 denotes E2
T3220 556-558 PR_EXT:000006506 denotes E3
T3221 575-583 CHEBI:15361 denotes pyruvate
T3222 575-583 _FRAGMENT denotes pyruvate
T3223 604-617 GO_EXT:0004738 denotes dehydrogenase
T3224 604-627 GO:0045254 denotes dehydrogenase complexes
T3225 588-603 CHEBI_EXT:2_oxoglutarate denotes α-ketoglutarate
T3226 588-617 GO_EXT:0004591 denotes α-ketoglutarate dehydrogenase
T3227 588-627 GO:0045240 denotes α-ketoglutarate dehydrogenase complexes
T3228 640-647 CHEBI_SO_EXT:glycine denotes glycine
R343 T3217 T3216 _lexicallyChainedTo subunits,α
R344 T3223 T3222 _lexicallyChainedTo dehydrogenase,pyruvate
R345 T3224 T3222 _lexicallyChainedTo dehydrogenase complexes,pyruvate

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3120 416-418 PR:000006506 denotes E3
T3123 484-494 PR:000004687 denotes β subunits
T3124 511-513 PR:000006300 denotes E2
T3125 556-558 PR:000006506 denotes E3
T3126 575-583 CHEBI:15361 denotes pyruvate
T3127 575-583 _FRAGMENT denotes pyruvate
T3128 604-627 GO:0045254 denotes dehydrogenase complexes
T3129 588-627 GO:0045240 denotes α-ketoglutarate dehydrogenase complexes
T3114 4-9 UBERON:0000178 denotes blood
T3115 10-14 CHEBI:22918 denotes BCAA
T3116 241-254 GO:0017086 denotes BCKDH complex
T3117 348-361 CHEBI:50488 denotes dihydrolipoyl
T3118 376-378 PR:000006300 denotes E2
T3119 387-400 CHEBI:50488 denotes dihydrolipoyl
T3121 474-475 _FRAGMENT denotes α
T3122 486-494 PR:000004686 denotes subunits
R339 T3122 T3121 _lexicallyChainedTo subunits,α
R340 T3128 T3127 _lexicallyChainedTo dehydrogenase complexes,pyruvate