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PMC:1448208 / 27259-28426 JSONTXT

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Id Subject Object Predicate Lexical cue
T24497 302-305 NN denotes LAP
T24496 298-301 DT denotes the
T24495 321-331 NNS denotes transgenes
T24494 293-297 CC denotes both
T24493 289-292 IN denotes for
T24492 280-288 JJ denotes positive
T24491 276-279 CC denotes and
T24490 273-275 NN denotes E2
T24489 262-272 JJ denotes endogenous
T24482 228-229 -LRB- denotes (
T24481 212-218 NN denotes rescue
T24480 219-227 NN denotes genotype
T24479 208-211 DT denotes the
T24478 204-207 VBD denotes had
T24477 199-203 WDT denotes that
T24476 192-198 VBN denotes tested
T24475 176-186 JJ denotes transgenic
T24474 187-191 NN denotes line
T24473 171-175 DT denotes each
T24472 166-170 IN denotes from
T24471 158-165 VBG denotes weaning
T24470 155-157 IN denotes at
T24469 149-154 JJ denotes alive
T24468 144-148 NNS denotes mice
T24467 141-143 IN denotes of
T24466 129-140 NNS denotes percentages
T24465 125-128 VBP denotes are
T24464 115-124 VBN denotes Presented
T24463 114-333 sentence denotes Presented are percentages of mice alive at weaning from each transgenic line tested that had the rescue genotype (i.e., homozygous for knockout of endogenous E2 and positive for both the LAP-tTA and TRE-E2 transgenes).
T24462 113-114 . denotes .
T24461 101-107 NN denotes rescue
T24460 108-113 NNS denotes lines
T24459 90-100 JJ denotes transgenic
T24458 87-89 IN denotes of
T24457 69-77 NN denotes Survival
T24456 67-69 , denotes ,
T24455 78-86 NN denotes analysis
T24454 66-67 LS denotes A
T24453 65-114 sentence denotes A, Survival analysis of transgenic rescue lines.
T24452 64-65 . denotes .
T24451 52-58 JJ denotes murine
T24450 47-51 NN denotes MSUD
T24449 34-46 JJ denotes intermediate
T24448 59-64 NN denotes model
T24447 30-33 DT denotes the
T24446 27-29 IN denotes of
T24445 10-26 NN denotes Characterization
T24680 1122-1132 VBN denotes sacrificed
T24679 1109-1121 RB denotes subsequently
T24678 1105-1108 CC denotes and
T24677 1096-1104 JJ denotes moribund
T24676 1086-1090 PRP denotes they
T24675 1091-1095 VBD denotes were
T24674 1080-1085 IN denotes until
T24673 1065-1069 VBD denotes were
T24672 1057-1064 NN denotes weaning
T24671 1054-1056 IN denotes at
T24670 1048-1053 JJ denotes alive
T24669 1070-1079 VBN denotes monitored
T24668 1043-1047 NNS denotes mice
T24667 1036-1042 NN denotes Rescue
T24666 1035-1167 sentence denotes Rescue mice alive at weaning were monitored until they were moribund and subsequently sacrificed or were found dead in their cages.
T24665 1034-1035 . denotes .
T24664 1030-1034 NN denotes 525A
T24663 1026-1029 CC denotes and
T24662 1024-1025 NN denotes A
T24661 1018-1023 NNS denotes Lines
T24660 1013-1017 IN denotes from
T24659 1008-1012 NNS denotes mice
T24658 1004-1007 IN denotes for
T24657 988-996 NN denotes Survival
T24656 986-988 , denotes ,
T24655 997-1003 NNS denotes curves
T24654 985-986 LS denotes D
T24653 984-1035 sentence denotes D, Survival curves for mice from Lines A and 525A.
T24652 983-984 . denotes .
T24651 975-976 SYM denotes
T24650 973-974 NN denotes P
T24649 971-973 , denotes ,
T24648 969-971 SYM denotes **
T24647 967-968 : denotes ;
T24646 977-983 CD denotes 0.0001
T24645 960-961 SYM denotes
T24644 958-959 NN denotes P
T24643 956-958 , denotes ,
T24642 962-967 CD denotes 0.001
T24641 955-956 SYM denotes *
T24640 954-984 sentence denotes *, P ≤ 0.001; **, P ≤ 0.0001.
T24639 953-954 . denotes .
T24638 944-948 NN denotes 525A
T24637 940-943 CC denotes and
T24636 938-939 NN denotes A
T24635 932-937 NNS denotes Lines
T24634 928-931 CC denotes and
T24633 949-953 NNS denotes mice
T24632 920-927 NN denotes control
T24631 917-919 IN denotes of
T24630 911-916 NN denotes liver
T24629 908-910 IN denotes in
T24628 892-898 NN denotes enzyme
T24627 886-891 NN denotes BCKDH
T24626 884-886 , denotes ,
T24625 899-907 NN denotes activity
T24624 883-884 LS denotes C
T24623 882-954 sentence denotes C, BCKDH enzyme activity in liver of control and Lines A and 525A mice.
T24622 881-882 . denotes .
T24621 874-875 SYM denotes <
T24620 872-873 NN denotes P
T24619 870-872 , denotes ,
T24618 868-870 SYM denotes **
T24617 866-867 : denotes ;
T24616 876-881 CD denotes 0.005
T24615 860-861 SYM denotes
T24614 858-859 NN denotes P
T24613 856-858 , denotes ,
T24612 862-866 CD denotes 0.01
T24611 855-856 SYM denotes *
T24610 854-882 sentence denotes *, P ≤ 0.01; **, P < 0.005.
T24609 853-854 . denotes .
T24608 845-853 VBN denotes analyzed
T24607 837-844 NNS denotes samples
T24606 834-836 IN denotes of
T24605 826-833 NNS denotes numbers
T24604 822-825 DT denotes the
T24603 807-811 NNS denotes bars
T24602 803-806 DT denotes the
T24601 800-802 IN denotes on
T24600 812-821 VBZ denotes indicates
T24599 792-799 NNS denotes numbers
T24598 788-791 DT denotes The
T24597 787-854 sentence denotes The numbers on the bars indicates the numbers of samples analyzed.
T24596 786-787 . denotes .
T24595 780-786 VBN denotes tested
T24594 775-779 NNS denotes ages
T24593 771-774 DT denotes all
T24592 768-770 IN denotes at
T24591 759-767 NNS denotes controls
T24590 756-758 IN denotes to
T24589 747-755 VBN denotes compared
T24588 742-746 NN denotes 525A
T24587 738-741 CC denotes and
T24586 736-737 NN denotes A
T24585 730-735 NNS denotes Lines
T24584 726-729 IN denotes for
T24583 718-725 JJR denotes greater
T24582 704-717 RB denotes significantly
T24581 699-703 VBD denotes were
T24580 692-698 NNS denotes values
T24579 683-684 HYPH denotes /
T24578 684-691 NN denotes alanine
T24577 679-683 NN denotes BCAA
T24576 678-787 sentence denotes BCAA/alanine values were significantly greater for Lines A and 525A compared to controls at all ages tested.
T24575 677-678 . denotes .
T24574 671-677 NN denotes valine
T24573 667-670 CC denotes and
T24572 665-667 , denotes ,
T24571 655-665 NN denotes isoleucine
T24570 653-655 , denotes ,
T24569 646-653 NN denotes leucine
T24568 643-645 IN denotes of
T24567 639-642 NN denotes sum
T24566 635-638 DT denotes the
T24565 625-634 VBP denotes represent
T24564 620-624 NN denotes BCAA
T24563 614-619 JJ denotes Total
T24562 613-678 sentence denotes Total BCAA represent the sum of leucine, isoleucine, and valine.
T24561 612-613 . denotes .
T24560 608-612 NN denotes 525A
T24559 604-607 CC denotes and
T24558 602-603 NN denotes A
T24557 596-601 NNS denotes Lines
T24556 592-595 CC denotes and
T24555 583-591 NNS denotes controls
T24554 578-582 IN denotes from
T24553 573-577 NNS denotes mice
T24552 570-572 IN denotes of
T24551 564-569 NN denotes blood
T24550 561-563 IN denotes in
T24549 553-560 NN denotes alanine
T24548 550-552 IN denotes to
T24547 545-549 NN denotes BCAA
T24546 539-544 JJ denotes total
T24545 536-538 IN denotes of
T24544 528-530 , denotes ,
T24543 530-535 NN denotes Ratio
T24542 527-528 LS denotes B
T24541 526-613 sentence denotes B, Ratio of total BCAA to alanine in blood of mice from controls and Lines A and 525A.
T24540 525-526 . denotes .
T24539 521-525 NN denotes line
T24538 516-520 DT denotes each
T24537 512-515 IN denotes for
T24536 499-511 NNS denotes observations
T24535 496-498 IN denotes of
T24534 488-495 NNS denotes numbers
T24533 484-487 DT denotes the
T24532 469-473 NNS denotes bars
T24531 465-468 DT denotes the
T24530 462-464 IN denotes on
T24529 474-483 VBZ denotes indicates
T24528 454-461 NNS denotes numbers
T24527 450-453 DT denotes The
T24526 449-526 sentence denotes The numbers on the bars indicates the numbers of observations for each line.
T24525 448-449 . denotes .
T24524 441-448 NNS denotes animals
T24523 438-440 IN denotes of
T24522 427-437 NN denotes population
T24521 422-426 DT denotes this
T24520 419-421 IN denotes in
T24519 407-409 VBZ denotes is
T24518 398-406 NN denotes genotype
T24517 393-397 DT denotes this
T24516 387-392 WDT denotes which
T24515 410-418 VBN denotes expected
T24514 384-386 IN denotes at
T24513 366-373 JJ denotes maximum
T24512 354-365 JJ denotes theoretical
T24511 374-383 NN denotes frequency
T24510 350-353 DT denotes the
T24509 339-346 VBN denotes plotted
T24508 347-349 VBZ denotes is
T24507 334-338 RB denotes Also
T24506 333-449 sentence denotes Also plotted is the theoretical maximum frequency at which this genotype is expected in this population of animals.
T24505 332-333 . denotes .
T24504 331-332 -RRB- denotes )
T24503 317-318 HYPH denotes -
T24502 318-320 NN denotes E2
T24501 314-317 NN denotes TRE
T24500 310-313 CC denotes and
T24499 305-306 HYPH denotes -
T24498 306-309 NN denotes tTA
T24688 1166-1167 . denotes .
T24488 259-261 IN denotes of
T24487 250-258 NN denotes knockout
T24486 246-249 IN denotes for
T24485 233-235 , denotes ,
T24484 229-233 FW denotes i.e.
T24483 235-245 JJ denotes homozygous
T24687 1161-1166 NNS denotes cages
T24686 1155-1160 PRP$ denotes their
T24685 1152-1154 IN denotes in
T24684 1147-1151 JJ denotes dead
T24683 1141-1146 VBN denotes found
T24682 1136-1140 VBD denotes were
T24681 1133-1135 CC denotes or
R6992 T24446 T24445 prep of,Characterization
R6993 T24447 T24448 det the,model
R6994 T24448 T24446 pobj model,of
R6995 T24449 T24448 amod intermediate,model
R6996 T24450 T24448 nmod MSUD,model
R6997 T24451 T24448 amod murine,model
R6998 T24452 T24445 punct .,Characterization
R6999 T24454 T24455 meta A,analysis
R7000 T24456 T24455 punct ", ",analysis
R7001 T24457 T24455 compound Survival,analysis
R7002 T24458 T24455 prep of,analysis
R7003 T24459 T24460 amod transgenic,lines
R7004 T24460 T24458 pobj lines,of
R7005 T24461 T24460 compound rescue,lines
R7006 T24462 T24455 punct .,analysis
R7007 T24464 T24465 dep Presented,are
R7008 T24466 T24465 nsubj percentages,are
R7009 T24467 T24466 prep of,percentages
R7010 T24468 T24467 pobj mice,of
R7011 T24469 T24468 amod alive,mice
R7012 T24470 T24469 prep at,alive
R7013 T24471 T24470 pobj weaning,at
R7014 T24472 T24468 prep from,mice
R7015 T24473 T24474 det each,line
R7016 T24474 T24472 pobj line,from
R7017 T24475 T24474 amod transgenic,line
R7018 T24476 T24474 acl tested,line
R7019 T24477 T24478 dep that,had
R7020 T24478 T24476 ccomp had,tested
R7021 T24479 T24480 det the,genotype
R7022 T24480 T24478 dobj genotype,had
R7023 T24481 T24480 compound rescue,genotype
R7024 T24482 T24483 punct (,homozygous
R7025 T24483 T24478 parataxis homozygous,had
R7026 T24484 T24483 advmod i.e.,homozygous
R7027 T24485 T24483 punct ", ",homozygous
R7028 T24486 T24483 prep for,homozygous
R7029 T24487 T24486 pobj knockout,for
R7030 T24488 T24487 prep of,knockout
R7031 T24489 T24490 amod endogenous,E2
R7032 T24490 T24488 pobj E2,of
R7033 T24491 T24483 cc and,homozygous
R7034 T24492 T24483 conj positive,homozygous
R7035 T24493 T24492 prep for,positive
R7036 T24494 T24495 preconj both,transgenes
R7037 T24495 T24493 pobj transgenes,for
R7038 T24496 T24495 det the,transgenes
R7039 T24497 T24498 nmod LAP,tTA
R7040 T24498 T24495 nmod tTA,transgenes
R7041 T24499 T24498 punct -,tTA
R7042 T24500 T24498 cc and,tTA
R7043 T24501 T24502 compound TRE,E2
R7044 T24502 T24498 conj E2,tTA
R7045 T24503 T24502 punct -,E2
R7046 T24504 T24483 punct ),homozygous
R7047 T24505 T24465 punct .,are
R7048 T24507 T24508 advmod Also,is
R7049 T24509 T24508 dep plotted,is
R7050 T24510 T24511 det the,frequency
R7051 T24511 T24508 nsubj frequency,is
R7052 T24512 T24511 amod theoretical,frequency
R7053 T24513 T24511 amod maximum,frequency
R7054 T24514 T24515 prep at,expected
R7055 T24515 T24511 relcl expected,frequency
R7056 T24516 T24514 pobj which,at
R7057 T24517 T24518 det this,genotype
R7058 T24518 T24515 nsubjpass genotype,expected
R7059 T24519 T24515 auxpass is,expected
R7060 T24520 T24515 prep in,expected
R7061 T24521 T24522 det this,population
R7062 T24522 T24520 pobj population,in
R7063 T24523 T24522 prep of,population
R7064 T24524 T24523 pobj animals,of
R7065 T24525 T24508 punct .,is
R7066 T24527 T24528 det The,numbers
R7067 T24528 T24529 nsubj numbers,indicates
R7068 T24530 T24528 prep on,numbers
R7069 T24531 T24532 det the,bars
R7070 T24532 T24530 pobj bars,on
R7071 T24533 T24534 det the,numbers
R7072 T24534 T24529 dobj numbers,indicates
R7073 T24535 T24534 prep of,numbers
R7074 T24536 T24535 pobj observations,of
R7075 T24537 T24534 prep for,numbers
R7076 T24538 T24539 det each,line
R7077 T24539 T24537 pobj line,for
R7078 T24540 T24529 punct .,indicates
R7079 T24542 T24543 meta B,Ratio
R7080 T24544 T24543 punct ", ",Ratio
R7081 T24545 T24543 prep of,Ratio
R7082 T24546 T24547 amod total,BCAA
R7083 T24547 T24545 pobj BCAA,of
R7084 T24548 T24543 prep to,Ratio
R7085 T24549 T24548 pobj alanine,to
R7086 T24550 T24543 prep in,Ratio
R7087 T24551 T24550 pobj blood,in
R7088 T24552 T24551 prep of,blood
R7089 T24553 T24552 pobj mice,of
R7090 T24554 T24543 prep from,Ratio
R7091 T24555 T24554 pobj controls,from
R7092 T24556 T24555 cc and,controls
R7093 T24557 T24558 compound Lines,A
R7094 T24558 T24555 conj A,controls
R7095 T24559 T24558 cc and,A
R7096 T24560 T24558 conj 525A,A
R7097 T24561 T24543 punct .,Ratio
R7098 T24563 T24564 amod Total,BCAA
R7099 T24564 T24565 nsubj BCAA,represent
R7100 T24566 T24567 det the,sum
R7101 T24567 T24565 dobj sum,represent
R7102 T24568 T24567 prep of,sum
R7103 T24569 T24568 pobj leucine,of
R7104 T24570 T24569 punct ", ",leucine
R7105 T24571 T24569 conj isoleucine,leucine
R7106 T24572 T24571 punct ", ",isoleucine
R7107 T24573 T24571 cc and,isoleucine
R7108 T24574 T24571 conj valine,isoleucine
R7109 T24575 T24565 punct .,represent
R7110 T24577 T24578 compound BCAA,alanine
R7111 T24578 T24580 compound alanine,values
R7112 T24579 T24578 punct /,alanine
R7113 T24580 T24581 nsubj values,were
R7114 T24582 T24583 advmod significantly,greater
R7115 T24583 T24581 acomp greater,were
R7116 T24584 T24583 prep for,greater
R7117 T24585 T24586 compound Lines,A
R7118 T24586 T24584 pobj A,for
R7119 T24587 T24586 cc and,A
R7120 T24588 T24586 conj 525A,A
R7121 T24589 T24583 prep compared,greater
R7122 T24590 T24589 prep to,compared
R7123 T24591 T24590 pobj controls,to
R7124 T24592 T24581 prep at,were
R7125 T24593 T24594 det all,ages
R7126 T24594 T24592 pobj ages,at
R7127 T24595 T24594 acl tested,ages
R7128 T24596 T24581 punct .,were
R7129 T24598 T24599 det The,numbers
R7130 T24599 T24600 nsubj numbers,indicates
R7131 T24601 T24599 prep on,numbers
R7132 T24602 T24603 det the,bars
R7133 T24603 T24601 pobj bars,on
R7134 T24604 T24605 det the,numbers
R7135 T24605 T24600 dobj numbers,indicates
R7136 T24606 T24605 prep of,numbers
R7137 T24607 T24606 pobj samples,of
R7138 T24608 T24607 acl analyzed,samples
R7139 T24609 T24600 punct .,indicates
R7140 T24611 T24612 punct *,0.01
R7141 T24612 T24616 ccomp 0.01,0.005
R7142 T24613 T24612 punct ", ",0.01
R7143 T24614 T24612 nsubj P,0.01
R7144 T24615 T24612 punct ≤,0.01
R7145 T24617 T24616 punct ;,0.005
R7146 T24618 T24616 punct **,0.005
R7147 T24619 T24616 punct ", ",0.005
R7148 T24620 T24616 nsubj P,0.005
R7149 T24621 T24616 punct <,0.005
R7150 T24622 T24616 punct .,0.005
R7151 T24624 T24625 meta C,activity
R7152 T24626 T24625 punct ", ",activity
R7153 T24627 T24625 compound BCKDH,activity
R7154 T24628 T24625 compound enzyme,activity
R7155 T24629 T24625 prep in,activity
R7156 T24630 T24629 pobj liver,in
R7157 T24631 T24630 prep of,liver
R7158 T24632 T24633 nmod control,mice
R7159 T24633 T24631 pobj mice,of
R7160 T24634 T24632 cc and,control
R7161 T24635 T24636 compound Lines,A
R7162 T24636 T24632 conj A,control
R7163 T24637 T24636 cc and,A
R7164 T24638 T24636 conj 525A,A
R7165 T24639 T24625 punct .,activity
R7166 T24641 T24642 punct *,0.001
R7167 T24642 T24646 ccomp 0.001,0.0001
R7168 T24643 T24642 punct ", ",0.001
R7169 T24644 T24642 nsubj P,0.001
R7170 T24645 T24642 punct ≤,0.001
R7171 T24647 T24646 punct ;,0.0001
R7172 T24648 T24646 punct **,0.0001
R7173 T24649 T24646 punct ", ",0.0001
R7174 T24650 T24646 nsubj P,0.0001
R7175 T24651 T24646 punct ≤,0.0001
R7176 T24652 T24646 punct .,0.0001
R7177 T24654 T24655 meta D,curves
R7178 T24656 T24655 punct ", ",curves
R7179 T24657 T24655 compound Survival,curves
R7180 T24658 T24655 prep for,curves
R7181 T24659 T24658 pobj mice,for
R7182 T24660 T24659 prep from,mice
R7183 T24661 T24662 compound Lines,A
R7184 T24662 T24660 pobj A,from
R7185 T24663 T24662 cc and,A
R7186 T24664 T24662 conj 525A,A
R7187 T24665 T24655 punct .,curves
R7188 T24667 T24668 compound Rescue,mice
R7189 T24668 T24669 nsubjpass mice,monitored
R7190 T24670 T24668 amod alive,mice
R7191 T24671 T24670 prep at,alive
R7192 T24672 T24671 pobj weaning,at
R7193 T24673 T24669 auxpass were,monitored
R7194 T24674 T24675 mark until,were
R7195 T24675 T24669 advcl were,monitored
R7196 T24676 T24675 nsubj they,were
R7197 T24677 T24675 acomp moribund,were
R7198 T24678 T24677 cc and,moribund
R7199 T24679 T24680 advmod subsequently,sacrificed
R7200 T24680 T24677 conj sacrificed,moribund
R7201 T24681 T24675 cc or,were
R7202 T24682 T24683 auxpass were,found
R7203 T24683 T24675 conj found,were
R7204 T24684 T24683 advcl dead,found
R7205 T24685 T24683 prep in,found
R7206 T24686 T24687 poss their,cages
R7207 T24687 T24685 pobj cages,in
R7208 T24688 T24669 punct .,monitored

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T24441 1008-1012 NCBITaxon:10088 denotes mice
T24444 1122-1132 GO_EXT:killing denotes sacrificed
T24443 1043-1047 NCBITaxon:10088 denotes mice
T24442 1036-1042 SO_EXT:sequence_rescue_process denotes Rescue
T24440 949-953 NCBITaxon:10088 denotes mice
T24439 911-916 UBERON:0002107 denotes liver
T24438 892-898 CHEBI_GO_SO_EXT:enzyme denotes enzyme
T24437 684-691 CHEBI_SO_EXT:alanine denotes alanine
T24436 679-683 CHEBI:22918 denotes BCAA
T24435 671-677 CHEBI_SO_EXT:valine denotes valine
T24434 655-665 CHEBI_SO_EXT:isoleucine denotes isoleucine
T24433 646-653 CHEBI_SO_EXT:leucine denotes leucine
T24432 620-624 CHEBI:22918 denotes BCAA
T24431 573-577 NCBITaxon:10088 denotes mice
T24430 564-569 UBERON:0000178 denotes blood
T24429 553-560 CHEBI_SO_EXT:alanine denotes alanine
T24428 545-549 CHEBI:22918 denotes BCAA
T24427 441-448 NCBITaxon:33208 denotes animals
T24426 398-406 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T24425 321-331 SO_EXT:0000902 denotes transgenes
T24424 318-320 PR_EXT:000006300 denotes E2
T24423 302-305 PR_EXT:000005308 denotes LAP
T24422 273-275 PR_EXT:000006300 denotes E2
T24421 219-227 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T24420 212-218 SO_EXT:sequence_rescue_process denotes rescue
T24419 176-186 SO_EXT:transgenic_entity denotes transgenic
T24418 144-148 NCBITaxon:10088 denotes mice
T24417 101-107 SO_EXT:sequence_rescue_process denotes rescue
T24416 90-100 SO_EXT:transgenic_entity denotes transgenic
T24415 52-58 NCBITaxon:10088 denotes murine

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T24414 1043-1047 NCBITaxon:10088 denotes mice
T24413 1008-1012 NCBITaxon:10088 denotes mice
T24412 949-953 NCBITaxon:10088 denotes mice
T24411 911-916 UBERON:0002107 denotes liver
T24410 679-683 CHEBI:22918 denotes BCAA
T24409 620-624 CHEBI:22918 denotes BCAA
T24408 573-577 NCBITaxon:10088 denotes mice
T24407 564-569 UBERON:0000178 denotes blood
T24406 545-549 CHEBI:22918 denotes BCAA
T24405 441-448 NCBITaxon:33208 denotes animals
T24404 321-331 SO:0000902 denotes transgenes
T24403 318-320 PR:000006300 denotes E2
T24402 302-305 PR:000005308 denotes LAP
T24401 273-275 PR:000006300 denotes E2
T24400 144-148 NCBITaxon:10088 denotes mice
T24399 52-58 NCBITaxon:10088 denotes murine