PMC:1448208 / 2104-7183 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T3318","span":{"begin":78,"end":88},"obj":"NN"},{"id":"T3319","span":{"begin":89,"end":91},"obj":"IN"},{"id":"T3320","span":{"begin":92,"end":100},"obj":"VBN"},{"id":"T3321","span":{"begin":101,"end":106},"obj":"NN"},{"id":"T3322","span":{"begin":100,"end":101},"obj":"HYPH"},{"id":"T3323","span":{"begin":117,"end":130},"obj":"NN"},{"id":"T3324","span":{"begin":107,"end":111},"obj":"NN"},{"id":"T3325","span":{"begin":112,"end":116},"obj":"NN"},{"id":"T3326","span":{"begin":131,"end":132},"obj":"-LRB-"},{"id":"T3327","span":{"begin":132,"end":137},"obj":"NN"},{"id":"T3328","span":{"begin":137,"end":138},"obj":"-RRB-"},{"id":"T3329","span":{"begin":138,"end":140},"obj":","},{"id":"T3330","span":{"begin":140,"end":141},"obj":"DT"},{"id":"T3331","span":{"begin":168,"end":175},"obj":"NN"},{"id":"T3332","span":{"begin":142,"end":155},"obj":"JJ"},{"id":"T3333","span":{"begin":156,"end":167},"obj":"NN"},{"id":"T3334","span":{"begin":176,"end":187},"obj":"JJ"},{"id":"T3335","span":{"begin":188,"end":191},"obj":"IN"},{"id":"T3336","span":{"begin":192,"end":195},"obj":"DT"},{"id":"T3337","span":{"begin":206,"end":221},"obj":"NN"},{"id":"T3338","span":{"begin":196,"end":205},"obj":"JJ"},{"id":"T3339","span":{"begin":222,"end":224},"obj":"IN"},{"id":"T3340","span":{"begin":225,"end":233},"obj":"VBN"},{"id":"T3341","span":{"begin":234,"end":239},"obj":"NN"},{"id":"T3342","span":{"begin":233,"end":234},"obj":"HYPH"},{"id":"T3343","span":{"begin":245,"end":250},"obj":"NNS"},{"id":"T3344","span":{"begin":240,"end":244},"obj":"NN"},{"id":"T3345","span":{"begin":251,"end":258},"obj":"VBN"},{"id":"T3346","span":{"begin":259,"end":263},"obj":"IN"},{"id":"T3347","span":{"begin":264,"end":272},"obj":"VBN"},{"id":"T3348","span":{"begin":273,"end":278},"obj":"NN"},{"id":"T3349","span":{"begin":272,"end":273},"obj":"HYPH"},{"id":"T3350","span":{"begin":285,"end":290},"obj":"NNS"},{"id":"T3351","span":{"begin":279,"end":284},"obj":"NN"},{"id":"T3352","span":{"begin":291,"end":292},"obj":"-LRB-"},{"id":"T3353","span":{"begin":292,"end":296},"obj":"NN"},{"id":"T3354","span":{"begin":296,"end":297},"obj":"-RRB-"},{"id":"T3355","span":{"begin":297,"end":299},"obj":","},{"id":"T3356","span":{"begin":299,"end":306},"obj":"NN"},{"id":"T3357","span":{"begin":306,"end":308},"obj":","},{"id":"T3358","span":{"begin":308,"end":318},"obj":"NN"},{"id":"T3359","span":{"begin":319,"end":322},"obj":"CC"},{"id":"T3360","span":{"begin":323,"end":329},"obj":"NN"},{"id":"T3361","span":{"begin":330,"end":331},"obj":"-LRB-"},{"id":"T3362","span":{"begin":343,"end":346},"obj":"VB"},{"id":"T3363","span":{"begin":331,"end":334},"obj":"IN"},{"id":"T3364","span":{"begin":335,"end":341},"obj":"NN"},{"id":"T3365","span":{"begin":341,"end":343},"obj":","},{"id":"T3366","span":{"begin":346,"end":348},"obj":":"},{"id":"T3367","span":{"begin":348,"end":349},"obj":"-LRB-"},{"id":"T3368","span":{"begin":349,"end":350},"obj":"CD"},{"id":"T3369","span":{"begin":350,"end":351},"obj":"-RRB-"},{"id":"T3370","span":{"begin":351,"end":352},"obj":"-RRB-"},{"id":"T3371","span":{"begin":352,"end":353},"obj":"."},{"id":"T3372","span":{"begin":353,"end":497},"obj":"sentence"},{"id":"T3373","span":{"begin":354,"end":362},"obj":"NNS"},{"id":"T3374","span":{"begin":401,"end":405},"obj":"VBP"},{"id":"T3375","span":{"begin":363,"end":367},"obj":"IN"},{"id":"T3376","span":{"begin":368,"end":372},"obj":"NN"},{"id":"T3377","span":{"begin":372,"end":374},"obj":","},{"id":"T3378","span":{"begin":374,"end":383},"obj":"VBG"},{"id":"T3379","span":{"begin":384,"end":386},"obj":"IN"},{"id":"T3380","span":{"begin":387,"end":390},"obj":"DT"},{"id":"T3381","span":{"begin":391,"end":399},"obj":"NN"},{"id":"T3382","span":{"begin":399,"end":401},"obj":","},{"id":"T3383","span":{"begin":406,"end":414},"obj":"JJ"},{"id":"T3384","span":{"begin":415,"end":422},"obj":"NNS"},{"id":"T3385","span":{"begin":423,"end":425},"obj":"IN"},{"id":"T3386","span":{"begin":426,"end":432},"obj":"NN"},{"id":"T3387","span":{"begin":433,"end":443},"obj":"NN"},{"id":"T3388","span":{"begin":444,"end":451},"obj":"VBG"},{"id":"T3389","span":{"begin":452,"end":454},"obj":"IN"},{"id":"T3390","span":{"begin":455,"end":462},"obj":"JJ"},{"id":"T3391","span":{"begin":482,"end":492},"obj":"NNS"},{"id":"T3392","span":{"begin":463,"end":472},"obj":"JJ"},{"id":"T3393","span":{"begin":473,"end":481},"obj":"JJ"},{"id":"T3394","span":{"begin":493,"end":494},"obj":"-LRB-"},{"id":"T3395","span":{"begin":494,"end":495},"obj":"CD"},{"id":"T3396","span":{"begin":495,"end":496},"obj":"-RRB-"},{"id":"T3397","span":{"begin":496,"end":497},"obj":"."},{"id":"T3398","span":{"begin":497,"end":625},"obj":"sentence"},{"id":"T3399","span":{"begin":498,"end":511},"obj":"RB"},{"id":"T3400","span":{"begin":512,"end":514},"obj":"CD"},{"id":"T3401","span":{"begin":514,"end":515},"obj":"NN"},{"id":"T3402","span":{"begin":533,"end":537},"obj":"VBP"},{"id":"T3403","span":{"begin":516,"end":518},"obj":"IN"},{"id":"T3404","span":{"begin":519,"end":523},"obj":"NN"},{"id":"T3405","span":{"begin":524,"end":532},"obj":"NNS"},{"id":"T3406","span":{"begin":538,"end":541},"obj":"DT"},{"id":"T3407","span":{"begin":550,"end":554},"obj":"NN"},{"id":"T3408","span":{"begin":542,"end":549},"obj":"JJ"},{"id":"T3409","span":{"begin":555,"end":557},"obj":"IN"},{"id":"T3410","span":{"begin":558,"end":561},"obj":"DT"},{"id":"T3411","span":{"begin":562,"end":569},"obj":"NN"},{"id":"T3412","span":{"begin":570,"end":574},"obj":"IN"},{"id":"T3413","span":{"begin":575,"end":580},"obj":"NN"},{"id":"T3414","span":{"begin":581,"end":589},"obj":"NN"},{"id":"T3415","span":{"begin":590,"end":592},"obj":"IN"},{"id":"T3416","span":{"begin":593,"end":596},"obj":"DT"},{"id":"T3417","span":{"begin":597,"end":602},"obj":"NN"},{"id":"T3418","span":{"begin":603,"end":605},"obj":"IN"},{"id":"T3419","span":{"begin":606,"end":607},"obj":"CD"},{"id":"T3420","span":{"begin":608,"end":609},"obj":"CD"},{"id":"T3421","span":{"begin":607,"end":608},"obj":"SYM"},{"id":"T3422","span":{"begin":609,"end":610},"obj":"NN"},{"id":"T3423","span":{"begin":611,"end":613},"obj":"IN"},{"id":"T3424","span":{"begin":614,"end":620},"obj":"JJ"},{"id":"T3425","span":{"begin":621,"end":622},"obj":"-LRB-"},{"id":"T3426","span":{"begin":622,"end":623},"obj":"CD"},{"id":"T3427","span":{"begin":623,"end":624},"obj":"-RRB-"},{"id":"T3428","span":{"begin":624,"end":625},"obj":"."},{"id":"T3429","span":{"begin":625,"end":714},"obj":"sentence"},{"id":"T3430","span":{"begin":626,"end":631},"obj":"DT"},{"id":"T3431","span":{"begin":632,"end":640},"obj":"NNS"},{"id":"T3432","span":{"begin":641,"end":645},"obj":"VBP"},{"id":"T3433","span":{"begin":646,"end":654},"obj":"RB"},{"id":"T3434","span":{"begin":655,"end":663},"obj":"VBN"},{"id":"T3435","span":{"begin":664,"end":670},"obj":"NNS"},{"id":"T3436","span":{"begin":671,"end":673},"obj":"IN"},{"id":"T3437","span":{"begin":674,"end":678},"obj":"NN"},{"id":"T3438","span":{"begin":679,"end":681},"obj":"IN"},{"id":"T3439","span":{"begin":682,"end":687},"obj":"NN"},{"id":"T3440","span":{"begin":688,"end":691},"obj":"CC"},{"id":"T3441","span":{"begin":692,"end":697},"obj":"JJ"},{"id":"T3442","span":{"begin":703,"end":709},"obj":"NNS"},{"id":"T3443","span":{"begin":698,"end":702},"obj":"NN"},{"id":"T3444","span":{"begin":710,"end":711},"obj":"-LRB-"},{"id":"T3445","span":{"begin":711,"end":712},"obj":"CD"},{"id":"T3446","span":{"begin":712,"end":713},"obj":"-RRB-"},{"id":"T3447","span":{"begin":713,"end":714},"obj":"."},{"id":"T3448","span":{"begin":714,"end":781},"obj":"sentence"},{"id":"T3449","span":{"begin":715,"end":722},"obj":"IN"},{"id":"T3450","span":{"begin":747,"end":750},"obj":"VBP"},{"id":"T3451","span":{"begin":723,"end":726},"obj":"DT"},{"id":"T3452","span":{"begin":735,"end":739},"obj":"NN"},{"id":"T3453","span":{"begin":727,"end":734},"obj":"JJ"},{"id":"T3454","span":{"begin":739,"end":741},"obj":","},{"id":"T3455","span":{"begin":741,"end":746},"obj":"EX"},{"id":"T3456","span":{"begin":751,"end":756},"obj":"JJ"},{"id":"T3457","span":{"begin":757,"end":765},"obj":"NNS"},{"id":"T3458","span":{"begin":766,"end":768},"obj":"IN"},{"id":"T3459","span":{"begin":769,"end":772},"obj":"DT"},{"id":"T3460","span":{"begin":773,"end":780},"obj":"NN"},{"id":"T3461","span":{"begin":780,"end":781},"obj":"."},{"id":"T3462","span":{"begin":781,"end":885},"obj":"sentence"},{"id":"T3463","span":{"begin":782,"end":790},"obj":"NNS"},{"id":"T3464","span":{"begin":833,"end":837},"obj":"VBP"},{"id":"T3465","span":{"begin":791,"end":795},"obj":"IN"},{"id":"T3466","span":{"begin":796,"end":799},"obj":"DT"},{"id":"T3467","span":{"begin":813,"end":817},"obj":"NN"},{"id":"T3468","span":{"begin":800,"end":812},"obj":"JJ"},{"id":"T3469","span":{"begin":818,"end":820},"obj":"IN"},{"id":"T3470","span":{"begin":821,"end":824},"obj":"DT"},{"id":"T3471","span":{"begin":825,"end":832},"obj":"NN"},{"id":"T3472","span":{"begin":838,"end":843},"obj":"NN"},{"id":"T3473","span":{"begin":844,"end":852},"obj":"NN"},{"id":"T3474","span":{"begin":853,"end":855},"obj":"IN"},{"id":"T3475","span":{"begin":856,"end":859},"obj":"DT"},{"id":"T3476","span":{"begin":860,"end":865},"obj":"NN"},{"id":"T3477","span":{"begin":866,"end":868},"obj":"IN"},{"id":"T3478","span":{"begin":869,"end":870},"obj":"CD"},{"id":"T3479","span":{"begin":871,"end":873},"obj":"CD"},{"id":"T3480","span":{"begin":870,"end":871},"obj":"SYM"},{"id":"T3481","span":{"begin":873,"end":874},"obj":"NN"},{"id":"T3482","span":{"begin":875,"end":877},"obj":"IN"},{"id":"T3483","span":{"begin":878,"end":884},"obj":"JJ"},{"id":"T3484","span":{"begin":884,"end":885},"obj":"."},{"id":"T3485","span":{"begin":885,"end":995},"obj":"sentence"},{"id":"T3486","span":{"begin":886,"end":888},"obj":"IN"},{"id":"T3487","span":{"begin":931,"end":938},"obj":"VBN"},{"id":"T3488","span":{"begin":889,"end":893},"obj":"JJ"},{"id":"T3489","span":{"begin":894,"end":902},"obj":"NNS"},{"id":"T3490","span":{"begin":903,"end":906},"obj":"DT"},{"id":"T3491","span":{"begin":907,"end":912},"obj":"NN"},{"id":"T3492","span":{"begin":913,"end":915},"obj":"IN"},{"id":"T3493","span":{"begin":916,"end":919},"obj":"DT"},{"id":"T3494","span":{"begin":920,"end":927},"obj":"NN"},{"id":"T3495","span":{"begin":928,"end":930},"obj":"VBZ"},{"id":"T3496","span":{"begin":938,"end":940},"obj":","},{"id":"T3497","span":{"begin":940,"end":943},"obj":"CC"},{"id":"T3498","span":{"begin":944,"end":949},"obj":"EX"},{"id":"T3499","span":{"begin":950,"end":953},"obj":"VBP"},{"id":"T3500","span":{"begin":954,"end":966},"obj":"RB"},{"id":"T3501","span":{"begin":967,"end":975},"obj":"VBN"},{"id":"T3502","span":{"begin":976,"end":982},"obj":"NNS"},{"id":"T3503","span":{"begin":983,"end":985},"obj":"IN"},{"id":"T3504","span":{"begin":986,"end":990},"obj":"NN"},{"id":"T3505","span":{"begin":991,"end":992},"obj":"-LRB-"},{"id":"T3506","span":{"begin":992,"end":993},"obj":"CD"},{"id":"T3507","span":{"begin":993,"end":994},"obj":"-RRB-"},{"id":"T3508","span":{"begin":994,"end":995},"obj":"."},{"id":"T3509","span":{"begin":995,"end":1153},"obj":"sentence"},{"id":"T3510","span":{"begin":996,"end":1004},"obj":"NNS"},{"id":"T3511","span":{"begin":1040,"end":1044},"obj":"VBP"},{"id":"T3512","span":{"begin":1005,"end":1009},"obj":"IN"},{"id":"T3513","span":{"begin":1010,"end":1013},"obj":"DT"},{"id":"T3514","span":{"begin":1027,"end":1031},"obj":"NN"},{"id":"T3515","span":{"begin":1014,"end":1026},"obj":"JJ"},{"id":"T3516","span":{"begin":1032,"end":1034},"obj":"IN"},{"id":"T3517","span":{"begin":1035,"end":1039},"obj":"NN"},{"id":"T3518","span":{"begin":1045,"end":1050},"obj":"NN"},{"id":"T3519","span":{"begin":1051,"end":1059},"obj":"NN"},{"id":"T3520","span":{"begin":1060,"end":1062},"obj":"IN"},{"id":"T3521","span":{"begin":1063,"end":1066},"obj":"DT"},{"id":"T3522","span":{"begin":1067,"end":1072},"obj":"NN"},{"id":"T3523","span":{"begin":1073,"end":1075},"obj":"IN"},{"id":"T3524","span":{"begin":1076,"end":1077},"obj":"CD"},{"id":"T3525","span":{"begin":1078,"end":1080},"obj":"CD"},{"id":"T3526","span":{"begin":1077,"end":1078},"obj":"SYM"},{"id":"T3527","span":{"begin":1080,"end":1081},"obj":"NN"},{"id":"T3528","span":{"begin":1082,"end":1085},"obj":"CC"},{"id":"T3529","span":{"begin":1086,"end":1092},"obj":"IN"},{"id":"T3530","span":{"begin":1138,"end":1141},"obj":"VBP"},{"id":"T3531","span":{"begin":1093,"end":1096},"obj":"DT"},{"id":"T3532","span":{"begin":1110,"end":1115},"obj":"NN"},{"id":"T3533","span":{"begin":1097,"end":1109},"obj":"JJ"},{"id":"T3534","span":{"begin":1116,"end":1119},"obj":"DT"},{"id":"T3535","span":{"begin":1131,"end":1137},"obj":"NNS"},{"id":"T3536","span":{"begin":1120,"end":1125},"obj":"NN"},{"id":"T3537","span":{"begin":1126,"end":1130},"obj":"NN"},{"id":"T3538","span":{"begin":1142,"end":1148},"obj":"JJ"},{"id":"T3539","span":{"begin":1149,"end":1150},"obj":"-LRB-"},{"id":"T3540","span":{"begin":1150,"end":1151},"obj":"CD"},{"id":"T3541","span":{"begin":1151,"end":1152},"obj":"-RRB-"},{"id":"T3542","span":{"begin":1152,"end":1153},"obj":"."},{"id":"T3543","span":{"begin":1153,"end":1352},"obj":"sentence"},{"id":"T3544","span":{"begin":1154,"end":1157},"obj":"DT"},{"id":"T3545","span":{"begin":1166,"end":1175},"obj":"NN"},{"id":"T3546","span":{"begin":1158,"end":1165},"obj":"JJ"},{"id":"T3547","span":{"begin":1210,"end":1212},"obj":"VBZ"},{"id":"T3548","span":{"begin":1176,"end":1178},"obj":"IN"},{"id":"T3549","span":{"begin":1179,"end":1183},"obj":"NN"},{"id":"T3550","span":{"begin":1184,"end":1186},"obj":"IN"},{"id":"T3551","span":{"begin":1187,"end":1190},"obj":"DT"},{"id":"T3552","span":{"begin":1199,"end":1209},"obj":"NN"},{"id":"T3553","span":{"begin":1191,"end":1198},"obj":"JJ"},{"id":"T3554","span":{"begin":1213,"end":1214},"obj":"CD"},{"id":"T3555","span":{"begin":1215,"end":1222},"obj":"CD"},{"id":"T3556","span":{"begin":1214,"end":1215},"obj":"SYM"},{"id":"T3557","span":{"begin":1223,"end":1224},"obj":"-LRB-"},{"id":"T3558","span":{"begin":1224,"end":1225},"obj":"CD"},{"id":"T3559","span":{"begin":1225,"end":1226},"obj":"-RRB-"},{"id":"T3560","span":{"begin":1226,"end":1228},"obj":","},{"id":"T3561","span":{"begin":1228,"end":1231},"obj":"CC"},{"id":"T3562","span":{"begin":1232,"end":1234},"obj":"IN"},{"id":"T3563","span":{"begin":1315,"end":1324},"obj":"VBN"},{"id":"T3564","span":{"begin":1235,"end":1242},"obj":"JJ"},{"id":"T3565","span":{"begin":1254,"end":1260},"obj":"NNS"},{"id":"T3566","span":{"begin":1243,"end":1253},"obj":"NN"},{"id":"T3567","span":{"begin":1260,"end":1262},"obj":","},{"id":"T3568","span":{"begin":1262,"end":1266},"obj":"JJ"},{"id":"T3569","span":{"begin":1267,"end":1269},"obj":"IN"},{"id":"T3570","span":{"begin":1270,"end":1280},"obj":"NNS"},{"id":"T3571","span":{"begin":1281,"end":1283},"obj":"IN"},{"id":"T3572","span":{"begin":1284,"end":1296},"obj":"NNP"},{"id":"T3573","span":{"begin":1296,"end":1298},"obj":","},{"id":"T3574","span":{"begin":1298,"end":1301},"obj":"DT"},{"id":"T3575","span":{"begin":1302,"end":1311},"obj":"NN"},{"id":"T3576","span":{"begin":1312,"end":1314},"obj":"VBZ"},{"id":"T3577","span":{"begin":1325,"end":1327},"obj":"TO"},{"id":"T3578","span":{"begin":1328,"end":1330},"obj":"VB"},{"id":"T3579","span":{"begin":1331,"end":1333},"obj":"IN"},{"id":"T3580","span":{"begin":1334,"end":1338},"obj":"JJ"},{"id":"T3581","span":{"begin":1339,"end":1341},"obj":"IN"},{"id":"T3582","span":{"begin":1342,"end":1343},"obj":"CD"},{"id":"T3583","span":{"begin":1344,"end":1347},"obj":"CD"},{"id":"T3584","span":{"begin":1343,"end":1344},"obj":"SYM"},{"id":"T3585","span":{"begin":1348,"end":1349},"obj":"-LRB-"},{"id":"T3586","span":{"begin":1349,"end":1350},"obj":"CD"},{"id":"T3587","span":{"begin":1350,"end":1351},"obj":"-RRB-"},{"id":"T3588","span":{"begin":1351,"end":1352},"obj":"."},{"id":"T3589","span":{"begin":1352,"end":1536},"obj":"sentence"},{"id":"T3590","span":{"begin":1353,"end":1356},"obj":"DT"},{"id":"T3591","span":{"begin":1363,"end":1370},"obj":"NN"},{"id":"T3592","span":{"begin":1357,"end":1362},"obj":"NN"},{"id":"T3593","span":{"begin":1402,"end":1410},"obj":"VBZ"},{"id":"T3594","span":{"begin":1370,"end":1372},"obj":","},{"id":"T3595","span":{"begin":1372,"end":1375},"obj":"DT"},{"id":"T3596","span":{"begin":1386,"end":1392},"obj":"NN"},{"id":"T3597","span":{"begin":1376,"end":1385},"obj":"JJ"},{"id":"T3598","span":{"begin":1393,"end":1395},"obj":"IN"},{"id":"T3599","span":{"begin":1396,"end":1400},"obj":"NN"},{"id":"T3600","span":{"begin":1400,"end":1402},"obj":","},{"id":"T3601","span":{"begin":1411,"end":1413},"obj":"IN"},{"id":"T3602","span":{"begin":1414,"end":1419},"obj":"CD"},{"id":"T3603","span":{"begin":1430,"end":1438},"obj":"NN"},{"id":"T3604","span":{"begin":1420,"end":1429},"obj":"JJ"},{"id":"T3605","span":{"begin":1438,"end":1440},"obj":","},{"id":"T3606","span":{"begin":1440,"end":1441},"obj":"DT"},{"id":"T3607","span":{"begin":1442,"end":1455},"obj":"NN"},{"id":"T3608","span":{"begin":1456,"end":1457},"obj":"-LRB-"},{"id":"T3609","span":{"begin":1457,"end":1459},"obj":"NN"},{"id":"T3610","span":{"begin":1459,"end":1460},"obj":"-RRB-"},{"id":"T3611","span":{"begin":1460,"end":1462},"obj":","},{"id":"T3612","span":{"begin":1462,"end":1463},"obj":"DT"},{"id":"T3613","span":{"begin":1478,"end":1490},"obj":"NN"},{"id":"T3614","span":{"begin":1464,"end":1477},"obj":"NN"},{"id":"T3615","span":{"begin":1491,"end":1492},"obj":"-LRB-"},{"id":"T3616","span":{"begin":1492,"end":1494},"obj":"NN"},{"id":"T3617","span":{"begin":1494,"end":1495},"obj":"-RRB-"},{"id":"T3618","span":{"begin":1495,"end":1497},"obj":","},{"id":"T3619","span":{"begin":1497,"end":1500},"obj":"CC"},{"id":"T3620","span":{"begin":1501,"end":1502},"obj":"DT"},{"id":"T3621","span":{"begin":1517,"end":1530},"obj":"NN"},{"id":"T3622","span":{"begin":1503,"end":1516},"obj":"NN"},{"id":"T3623","span":{"begin":1531,"end":1532},"obj":"-LRB-"},{"id":"T3624","span":{"begin":1532,"end":1534},"obj":"NN"},{"id":"T3625","span":{"begin":1534,"end":1535},"obj":"-RRB-"},{"id":"T3626","span":{"begin":1535,"end":1536},"obj":"."},{"id":"T3627","span":{"begin":1536,"end":1615},"obj":"sentence"},{"id":"T3628","span":{"begin":1537,"end":1540},"obj":"DT"},{"id":"T3629","span":{"begin":1544,"end":1553},"obj":"NN"},{"id":"T3630","span":{"begin":1541,"end":1543},"obj":"NN"},{"id":"T3631","span":{"begin":1554,"end":1556},"obj":"VBZ"},{"id":"T3632","span":{"begin":1557,"end":1558},"obj":"DT"},{"id":"T3633","span":{"begin":1559,"end":1573},"obj":"NN"},{"id":"T3634","span":{"begin":1574,"end":1582},"obj":"VBN"},{"id":"T3635","span":{"begin":1583,"end":1585},"obj":"IN"},{"id":"T3636","span":{"begin":1586,"end":1589},"obj":"CD"},{"id":"T3637","span":{"begin":1590,"end":1591},"obj":"NN"},{"id":"T3638","span":{"begin":1602,"end":1610},"obj":"NNS"},{"id":"T3639","span":{"begin":1592,"end":1595},"obj":"CC"},{"id":"T3640","span":{"begin":1596,"end":1599},"obj":"CD"},{"id":"T3641","span":{"begin":1600,"end":1601},"obj":"NN"},{"id":"T3642","span":{"begin":1611,"end":1612},"obj":"-LRB-"},{"id":"T3643","span":{"begin":1612,"end":1613},"obj":"CD"},{"id":"T3644","span":{"begin":1613,"end":1614},"obj":"-RRB-"},{"id":"T3645","span":{"begin":1614,"end":1615},"obj":"."},{"id":"T3646","span":{"begin":1615,"end":1784},"obj":"sentence"},{"id":"T3647","span":{"begin":1616,"end":1619},"obj":"DT"},{"id":"T3648","span":{"begin":1630,"end":1640},"obj":"NNS"},{"id":"T3649","span":{"begin":1620,"end":1622},"obj":"NN"},{"id":"T3650","span":{"begin":1623,"end":1626},"obj":"CC"},{"id":"T3651","span":{"begin":1627,"end":1629},"obj":"NN"},{"id":"T3652","span":{"begin":1641,"end":1644},"obj":"VBP"},{"id":"T3653","span":{"begin":1645,"end":1653},"obj":"JJ"},{"id":"T3654","span":{"begin":1654,"end":1656},"obj":"IN"},{"id":"T3655","span":{"begin":1657,"end":1662},"obj":"NN"},{"id":"T3656","span":{"begin":1662,"end":1664},"obj":","},{"id":"T3657","span":{"begin":1664,"end":1671},"obj":"IN"},{"id":"T3658","span":{"begin":1683,"end":1687},"obj":"VBN"},{"id":"T3659","span":{"begin":1672,"end":1674},"obj":"NN"},{"id":"T3660","span":{"begin":1675,"end":1677},"obj":"VBZ"},{"id":"T3661","span":{"begin":1678,"end":1682},"obj":"RB"},{"id":"T3662","span":{"begin":1688,"end":1690},"obj":"IN"},{"id":"T3663","span":{"begin":1691,"end":1699},"obj":"NN"},{"id":"T3664","span":{"begin":1734,"end":1743},"obj":"NNS"},{"id":"T3665","span":{"begin":1700,"end":1703},"obj":"CC"},{"id":"T3666","span":{"begin":1704,"end":1705},"obj":"NN"},{"id":"T3667","span":{"begin":1706,"end":1719},"obj":"NN"},{"id":"T3668","span":{"begin":1705,"end":1706},"obj":"HYPH"},{"id":"T3669","span":{"begin":1720,"end":1733},"obj":"NN"},{"id":"T3670","span":{"begin":1744,"end":1745},"obj":"-LRB-"},{"id":"T3671","span":{"begin":1745,"end":1746},"obj":"CD"},{"id":"T3672","span":{"begin":1746,"end":1747},"obj":"-RRB-"},{"id":"T3673","span":{"begin":1748,"end":1751},"obj":"CC"},{"id":"T3674","span":{"begin":1752,"end":1755},"obj":"DT"},{"id":"T3675","span":{"begin":1773,"end":1779},"obj":"NN"},{"id":"T3676","span":{"begin":1756,"end":1763},"obj":"NN"},{"id":"T3677","span":{"begin":1764,"end":1772},"obj":"NN"},{"id":"T3678","span":{"begin":1780,"end":1781},"obj":"-LRB-"},{"id":"T3679","span":{"begin":1781,"end":1782},"obj":"CD"},{"id":"T3680","span":{"begin":1782,"end":1783},"obj":"-RRB-"},{"id":"T3681","span":{"begin":1783,"end":1784},"obj":"."},{"id":"T3682","span":{"begin":1784,"end":2027},"obj":"sentence"},{"id":"T3683","span":{"begin":1785,"end":1790},"obj":"NN"},{"id":"T3684","span":{"begin":1799,"end":1809},"obj":"VBN"},{"id":"T3685","span":{"begin":1791,"end":1793},"obj":"VBZ"},{"id":"T3686","span":{"begin":1794,"end":1798},"obj":"RB"},{"id":"T3687","span":{"begin":1810,"end":1814},"obj":"IN"},{"id":"T3688","span":{"begin":1815,"end":1818},"obj":"CD"},{"id":"T3689","span":{"begin":1830,"end":1838},"obj":"NN"},{"id":"T3690","span":{"begin":1819,"end":1829},"obj":"JJ"},{"id":"T3691","span":{"begin":1838,"end":1840},"obj":","},{"id":"T3692","span":{"begin":1840,"end":1841},"obj":"DT"},{"id":"T3693","span":{"begin":1851,"end":1857},"obj":"NN"},{"id":"T3694","span":{"begin":1842,"end":1850},"obj":"JJ"},{"id":"T3695","span":{"begin":1858,"end":1861},"obj":"CC"},{"id":"T3696","span":{"begin":1862,"end":1863},"obj":"DT"},{"id":"T3697","span":{"begin":1864,"end":1875},"obj":"NN"},{"id":"T3698","span":{"begin":1876,"end":1881},"obj":"WDT"},{"id":"T3699","span":{"begin":1882,"end":1890},"obj":"VBP"},{"id":"T3700","span":{"begin":1891,"end":1894},"obj":"DT"},{"id":"T3701","span":{"begin":1895,"end":1903},"obj":"NN"},{"id":"T3702","span":{"begin":1904,"end":1906},"obj":"IN"},{"id":"T3703","span":{"begin":1907,"end":1911},"obj":"DT"},{"id":"T3704","span":{"begin":1912,"end":1918},"obj":"NN"},{"id":"T3705","span":{"begin":1919,"end":1926},"obj":"IN"},{"id":"T3706","span":{"begin":1927,"end":1928},"obj":"DT"},{"id":"T3707","span":{"begin":1995,"end":2000},"obj":"NN"},{"id":"T3708","span":{"begin":1929,"end":1944},"obj":"NN"},{"id":"T3709","span":{"begin":1945,"end":1946},"obj":"-LRB-"},{"id":"T3710","span":{"begin":1946,"end":1958},"obj":"NN"},{"id":"T3711","span":{"begin":1958,"end":1959},"obj":"-RRB-"},{"id":"T3712","span":{"begin":1960,"end":1963},"obj":"CC"},{"id":"T3713","span":{"begin":1964,"end":1981},"obj":"NN"},{"id":"T3714","span":{"begin":1982,"end":1983},"obj":"-LRB-"},{"id":"T3715","span":{"begin":1983,"end":1993},"obj":"NN"},{"id":"T3716","span":{"begin":1993,"end":1994},"obj":"-RRB-"},{"id":"T3717","span":{"begin":2001,"end":2003},"obj":"IN"},{"id":"T3718","span":{"begin":2004,"end":2007},"obj":"DT"},{"id":"T3719","span":{"begin":2013,"end":2020},"obj":"NN"},{"id":"T3720","span":{"begin":2008,"end":2010},"obj":"NN"},{"id":"T3721","span":{"begin":2011,"end":2012},"obj":"NN"},{"id":"T3722","span":{"begin":2021,"end":2022},"obj":"-LRB-"},{"id":"T3723","span":{"begin":2024,"end":2025},"obj":"CD"},{"id":"T3724","span":{"begin":2022,"end":2023},"obj":"CD"},{"id":"T3725","span":{"begin":2023,"end":2024},"obj":","},{"id":"T3726","span":{"begin":2025,"end":2026},"obj":"-RRB-"},{"id":"T3727","span":{"begin":2026,"end":2027},"obj":"."},{"id":"T3728","span":{"begin":2027,"end":2195},"obj":"sentence"},{"id":"T3729","span":{"begin":2028,"end":2037},"obj":"NNS"},{"id":"T3730","span":{"begin":2096,"end":2105},"obj":"VBN"},{"id":"T3731","span":{"begin":2038,"end":2040},"obj":"IN"},{"id":"T3732","span":{"begin":2041,"end":2044},"obj":"DT"},{"id":"T3733","span":{"begin":2045,"end":2050},"obj":"NNS"},{"id":"T3734","span":{"begin":2051,"end":2053},"obj":"IN"},{"id":"T3735","span":{"begin":2054,"end":2057},"obj":"DT"},{"id":"T3736","span":{"begin":2068,"end":2076},"obj":"NNS"},{"id":"T3737","span":{"begin":2058,"end":2060},"obj":"NN"},{"id":"T3738","span":{"begin":2061,"end":2064},"obj":"CC"},{"id":"T3739","span":{"begin":2065,"end":2067},"obj":"NN"},{"id":"T3740","span":{"begin":2077,"end":2079},"obj":"IN"},{"id":"T3741","span":{"begin":2080,"end":2085},"obj":"NN"},{"id":"T3742","span":{"begin":2086,"end":2090},"obj":"VBP"},{"id":"T3743","span":{"begin":2091,"end":2095},"obj":"VBN"},{"id":"T3744","span":{"begin":2167,"end":2170},"obj":"VBP"},{"id":"T3745","span":{"begin":2105,"end":2107},"obj":","},{"id":"T3746","span":{"begin":2107,"end":2114},"obj":"RB"},{"id":"T3747","span":{"begin":2114,"end":2116},"obj":","},{"id":"T3748","span":{"begin":2116,"end":2119},"obj":"DT"},{"id":"T3749","span":{"begin":2120,"end":2128},"obj":"NN"},{"id":"T3750","span":{"begin":2129,"end":2131},"obj":"IN"},{"id":"T3751","span":{"begin":2132,"end":2136},"obj":"NN"},{"id":"T3752","span":{"begin":2137,"end":2146},"obj":"NNS"},{"id":"T3753","span":{"begin":2147,"end":2157},"obj":"VBN"},{"id":"T3754","span":{"begin":2158,"end":2162},"obj":"RB"},{"id":"T3755","span":{"begin":2163,"end":2166},"obj":"RB"},{"id":"T3756","span":{"begin":2171,"end":2173},"obj":"IN"},{"id":"T3757","span":{"begin":2174,"end":2177},"obj":"DT"},{"id":"T3758","span":{"begin":2181,"end":2188},"obj":"NN"},{"id":"T3759","span":{"begin":2178,"end":2180},"obj":"NN"},{"id":"T3760","span":{"begin":2189,"end":2190},"obj":"-LRB-"},{"id":"T3761","span":{"begin":2192,"end":2193},"obj":"CD"},{"id":"T3762","span":{"begin":2190,"end":2191},"obj":"CD"},{"id":"T3763","span":{"begin":2191,"end":2192},"obj":","},{"id":"T3764","span":{"begin":2193,"end":2194},"obj":"-RRB-"},{"id":"T3765","span":{"begin":2194,"end":2195},"obj":"."},{"id":"T3766","span":{"begin":2195,"end":2302},"obj":"sentence"},{"id":"T3767","span":{"begin":2196,"end":2198},"obj":"IN"},{"id":"T3768","span":{"begin":2233,"end":2243},"obj":"VBN"},{"id":"T3769","span":{"begin":2199,"end":2203},"obj":"NN"},{"id":"T3770","span":{"begin":2203,"end":2205},"obj":","},{"id":"T3771","span":{"begin":2205,"end":2210},"obj":"NNS"},{"id":"T3772","span":{"begin":2211,"end":2213},"obj":"IN"},{"id":"T3773","span":{"begin":2214,"end":2218},"obj":"NN"},{"id":"T3774","span":{"begin":2219,"end":2223},"obj":"VBP"},{"id":"T3775","span":{"begin":2224,"end":2227},"obj":"RB"},{"id":"T3776","span":{"begin":2228,"end":2232},"obj":"VBN"},{"id":"T3777","span":{"begin":2244,"end":2248},"obj":"IN"},{"id":"T3778","span":{"begin":2249,"end":2256},"obj":"NNS"},{"id":"T3779","span":{"begin":2257,"end":2259},"obj":"IN"},{"id":"T3780","span":{"begin":2260,"end":2263},"obj":"DT"},{"id":"T3781","span":{"begin":2275,"end":2281},"obj":"NN"},{"id":"T3782","span":{"begin":2264,"end":2274},"obj":"JJ"},{"id":"T3783","span":{"begin":2282,"end":2285},"obj":"CC"},{"id":"T3784","span":{"begin":2286,"end":2297},"obj":"NN"},{"id":"T3785","span":{"begin":2298,"end":2299},"obj":"-LRB-"},{"id":"T3786","span":{"begin":2299,"end":2300},"obj":"CD"},{"id":"T3787","span":{"begin":2300,"end":2301},"obj":"-RRB-"},{"id":"T3788","span":{"begin":2301,"end":2302},"obj":"."},{"id":"T3789","span":{"begin":2302,"end":2412},"obj":"sentence"},{"id":"T3790","span":{"begin":2303,"end":2310},"obj":"JJ"},{"id":"T3791","span":{"begin":2311,"end":2321},"obj":"NN"},{"id":"T3792","span":{"begin":2339,"end":2345},"obj":"VBZ"},{"id":"T3793","span":{"begin":2322,"end":2324},"obj":"IN"},{"id":"T3794","span":{"begin":2325,"end":2329},"obj":"NN"},{"id":"T3795","span":{"begin":2330,"end":2338},"obj":"NNS"},{"id":"T3796","span":{"begin":2346,"end":2348},"obj":"IN"},{"id":"T3797","span":{"begin":2349,"end":2350},"obj":"DT"},{"id":"T3798","span":{"begin":2375,"end":2386},"obj":"NN"},{"id":"T3799","span":{"begin":2351,"end":2357},"obj":"JJ"},{"id":"T3800","span":{"begin":2358,"end":2366},"obj":"JJ"},{"id":"T3801","span":{"begin":2367,"end":2374},"obj":"JJ"},{"id":"T3802","span":{"begin":2387,"end":2389},"obj":"IN"},{"id":"T3803","span":{"begin":2390,"end":2397},"obj":"NN"},{"id":"T3804","span":{"begin":2398,"end":2400},"obj":"CC"},{"id":"T3805","span":{"begin":2401,"end":2405},"obj":"NN"},{"id":"T3806","span":{"begin":2406,"end":2407},"obj":"-LRB-"},{"id":"T3807","span":{"begin":2409,"end":2410},"obj":"CD"},{"id":"T3808","span":{"begin":2407,"end":2408},"obj":"CD"},{"id":"T3809","span":{"begin":2408,"end":2409},"obj":","},{"id":"T3810","span":{"begin":2410,"end":2411},"obj":"-RRB-"},{"id":"T3811","span":{"begin":2411,"end":2412},"obj":"."},{"id":"T3812","span":{"begin":2412,"end":2588},"obj":"sentence"},{"id":"T3813","span":{"begin":2413,"end":2417},"obj":"PDT"},{"id":"T3814","span":{"begin":2428,"end":2438},"obj":"NN"},{"id":"T3815","span":{"begin":2418,"end":2419},"obj":"DT"},{"id":"T3816","span":{"begin":2420,"end":2427},"obj":"JJ"},{"id":"T3817","span":{"begin":2464,"end":2466},"obj":"VBZ"},{"id":"T3818","span":{"begin":2439,"end":2441},"obj":"IN"},{"id":"T3819","span":{"begin":2442,"end":2445},"obj":"DT"},{"id":"T3820","span":{"begin":2446,"end":2453},"obj":"NN"},{"id":"T3821","span":{"begin":2453,"end":2455},"obj":","},{"id":"T3822","span":{"begin":2455,"end":2462},"obj":"RB"},{"id":"T3823","span":{"begin":2462,"end":2464},"obj":","},{"id":"T3824","span":{"begin":2467,"end":2470},"obj":"RB"},{"id":"T3825","span":{"begin":2471,"end":2479},"obj":"RB"},{"id":"T3826","span":{"begin":2480,"end":2492},"obj":"JJ"},{"id":"T3827","span":{"begin":2493,"end":2503},"obj":"RB"},{"id":"T3828","span":{"begin":2504,"end":2506},"obj":"IN"},{"id":"T3829","span":{"begin":2507,"end":2512},"obj":"NNS"},{"id":"T3830","span":{"begin":2513,"end":2515},"obj":"IN"},{"id":"T3831","span":{"begin":2516,"end":2525},"obj":"JJ"},{"id":"T3832","span":{"begin":2526,"end":2540},"obj":"NN"},{"id":"T3833","span":{"begin":2541,"end":2544},"obj":"IN"},{"id":"T3834","span":{"begin":2545,"end":2547},"obj":"IN"},{"id":"T3835","span":{"begin":2548,"end":2557},"obj":"NN"},{"id":"T3836","span":{"begin":2557,"end":2559},"obj":","},{"id":"T3837","span":{"begin":2559,"end":2567},"obj":"NNS"},{"id":"T3838","span":{"begin":2568,"end":2571},"obj":"CC"},{"id":"T3839","span":{"begin":2572,"end":2577},"obj":"JJ"},{"id":"T3840","span":{"begin":2578,"end":2587},"obj":"NNS"},{"id":"T3841","span":{"begin":2587,"end":2588},"obj":"."},{"id":"T3842","span":{"begin":2588,"end":2744},"obj":"sentence"},{"id":"T3843","span":{"begin":2589,"end":2591},"obj":"IN"},{"id":"T3844","span":{"begin":2629,"end":2631},"obj":"VBZ"},{"id":"T3845","span":{"begin":2592,"end":2597},"obj":"NN"},{"id":"T3846","span":{"begin":2598,"end":2600},"obj":"IN"},{"id":"T3847","span":{"begin":2601,"end":2608},"obj":"JJ"},{"id":"T3848","span":{"begin":2609,"end":2621},"obj":"NN"},{"id":"T3849","span":{"begin":2621,"end":2623},"obj":","},{"id":"T3850","span":{"begin":2623,"end":2628},"obj":"EX"},{"id":"T3851","span":{"begin":2632,"end":2643},"obj":"JJ"},{"id":"T3852","span":{"begin":2644,"end":2653},"obj":"NN"},{"id":"T3853","span":{"begin":2654,"end":2664},"obj":"VBN"},{"id":"T3854","span":{"begin":2665,"end":2669},"obj":"IN"},{"id":"T3855","span":{"begin":2670,"end":2674},"obj":"NN"},{"id":"T3856","span":{"begin":2675,"end":2678},"obj":"CC"},{"id":"T3857","span":{"begin":2679,"end":2684},"obj":"EX"},{"id":"T3858","span":{"begin":2685,"end":2687},"obj":"VBZ"},{"id":"T3859","span":{"begin":2688,"end":2689},"obj":"DT"},{"id":"T3860","span":{"begin":2695,"end":2704},"obj":"NN"},{"id":"T3861","span":{"begin":2690,"end":2694},"obj":"JJ"},{"id":"T3862","span":{"begin":2705,"end":2707},"obj":"IN"},{"id":"T3863","span":{"begin":2708,"end":2714},"obj":"JJ"},{"id":"T3864","span":{"begin":2715,"end":2726},"obj":"NN"},{"id":"T3865","span":{"begin":2727,"end":2729},"obj":"IN"},{"id":"T3866","span":{"begin":2730,"end":2739},"obj":"NNS"},{"id":"T3867","span":{"begin":2740,"end":2741},"obj":"-LRB-"},{"id":"T3868","span":{"begin":2741,"end":2742},"obj":"CD"},{"id":"T3869","span":{"begin":2742,"end":2743},"obj":"-RRB-"},{"id":"T3870","span":{"begin":2743,"end":2744},"obj":"."},{"id":"T3871","span":{"begin":2744,"end":2958},"obj":"sentence"},{"id":"T3872","span":{"begin":2745,"end":2752},"obj":"IN"},{"id":"T3873","span":{"begin":2917,"end":2924},"obj":"VBN"},{"id":"T3874","span":{"begin":2753,"end":2755},"obj":"IN"},{"id":"T3875","span":{"begin":2756,"end":2759},"obj":"DT"},{"id":"T3876","span":{"begin":2768,"end":2772},"obj":"NN"},{"id":"T3877","span":{"begin":2760,"end":2767},"obj":"JJ"},{"id":"T3878","span":{"begin":2773,"end":2775},"obj":"IN"},{"id":"T3879","span":{"begin":2776,"end":2779},"obj":"DT"},{"id":"T3880","span":{"begin":2780,"end":2785},"obj":"NN"},{"id":"T3881","span":{"begin":2786,"end":2788},"obj":"IN"},{"id":"T3882","span":{"begin":2789,"end":2794},"obj":"NN"},{"id":"T3883","span":{"begin":2795,"end":2799},"obj":"NN"},{"id":"T3884","span":{"begin":2800,"end":2810},"obj":"NN"},{"id":"T3885","span":{"begin":2811,"end":2814},"obj":"CC"},{"id":"T3886","span":{"begin":2815,"end":2823},"obj":"JJ"},{"id":"T3887","span":{"begin":2824,"end":2828},"obj":"JJ"},{"id":"T3888","span":{"begin":2823,"end":2824},"obj":"SYM"},{"id":"T3889","span":{"begin":2829,"end":2835},"obj":"NNS"},{"id":"T3890","span":{"begin":2836,"end":2838},"obj":"IN"},{"id":"T3891","span":{"begin":2839,"end":2844},"obj":"NN"},{"id":"T3892","span":{"begin":2845,"end":2853},"obj":"NN"},{"id":"T3893","span":{"begin":2854,"end":2856},"obj":"IN"},{"id":"T3894","span":{"begin":2857,"end":2862},"obj":"JJ"},{"id":"T3895","span":{"begin":2863,"end":2868},"obj":"NN"},{"id":"T3896","span":{"begin":2869,"end":2870},"obj":"-LRB-"},{"id":"T3897","span":{"begin":2870,"end":2872},"obj":"CD"},{"id":"T3898","span":{"begin":2872,"end":2873},"obj":"SYM"},{"id":"T3899","span":{"begin":2873,"end":2875},"obj":"CD"},{"id":"T3900","span":{"begin":2875,"end":2876},"obj":"-RRB-"},{"id":"T3901","span":{"begin":2876,"end":2878},"obj":","},{"id":"T3902","span":{"begin":2878,"end":2879},"obj":"DT"},{"id":"T3903","span":{"begin":2884,"end":2889},"obj":"NNS"},{"id":"T3904","span":{"begin":2880,"end":2883},"obj":"JJ"},{"id":"T3905","span":{"begin":2890,"end":2892},"obj":"IN"},{"id":"T3906","span":{"begin":2893,"end":2897},"obj":"NN"},{"id":"T3907","span":{"begin":2898,"end":2902},"obj":"VBP"},{"id":"T3908","span":{"begin":2903,"end":2911},"obj":"RB"},{"id":"T3909","span":{"begin":2912,"end":2916},"obj":"VBN"},{"id":"T3910","span":{"begin":2925,"end":2927},"obj":"IN"},{"id":"T3911","span":{"begin":2928,"end":2933},"obj":"NN"},{"id":"T3912","span":{"begin":2934,"end":2949},"obj":"NN"},{"id":"T3913","span":{"begin":2950,"end":2951},"obj":"-LRB-"},{"id":"T3914","span":{"begin":2951,"end":2953},"obj":"CD"},{"id":"T3915","span":{"begin":2953,"end":2954},"obj":"SYM"},{"id":"T3916","span":{"begin":2954,"end":2956},"obj":"CD"},{"id":"T3917","span":{"begin":2956,"end":2957},"obj":"-RRB-"},{"id":"T3918","span":{"begin":2957,"end":2958},"obj":"."},{"id":"T3919","span":{"begin":2958,"end":3078},"obj":"sentence"},{"id":"T3920","span":{"begin":2959,"end":2964},"obj":"IN"},{"id":"T3921","span":{"begin":3013,"end":3015},"obj":"VBZ"},{"id":"T3922","span":{"begin":2965,"end":2968},"obj":"DT"},{"id":"T3923","span":{"begin":2980,"end":2987},"obj":"NN"},{"id":"T3924","span":{"begin":2969,"end":2974},"obj":"JJ"},{"id":"T3925","span":{"begin":2975,"end":2979},"obj":"NN"},{"id":"T3926","span":{"begin":2974,"end":2975},"obj":"HYPH"},{"id":"T3927","span":{"begin":2988,"end":2990},"obj":"IN"},{"id":"T3928","span":{"begin":2991,"end":2996},"obj":"NN"},{"id":"T3929","span":{"begin":2997,"end":3012},"obj":"NN"},{"id":"T3930","span":{"begin":3072,"end":3077},"obj":"VBN"},{"id":"T3931","span":{"begin":3016,"end":3027},"obj":"JJ"},{"id":"T3932","span":{"begin":3027,"end":3029},"obj":","},{"id":"T3933","span":{"begin":3029,"end":3033},"obj":"JJ"},{"id":"T3934","span":{"begin":3034,"end":3038},"obj":"NN"},{"id":"T3935","span":{"begin":3033,"end":3034},"obj":"HYPH"},{"id":"T3936","span":{"begin":3039,"end":3046},"obj":"NNS"},{"id":"T3937","span":{"begin":3047,"end":3049},"obj":"IN"},{"id":"T3938","span":{"begin":3050,"end":3054},"obj":"DT"},{"id":"T3939","span":{"begin":3055,"end":3063},"obj":"NN"},{"id":"T3940","span":{"begin":3064,"end":3067},"obj":"VBP"},{"id":"T3941","span":{"begin":3068,"end":3071},"obj":"RB"},{"id":"T3942","span":{"begin":3077,"end":3078},"obj":"."},{"id":"T3943","span":{"begin":3078,"end":3217},"obj":"sentence"},{"id":"T3944","span":{"begin":3079,"end":3086},"obj":"RB"},{"id":"T3945","span":{"begin":3111,"end":3119},"obj":"VBN"},{"id":"T3946","span":{"begin":3086,"end":3088},"obj":","},{"id":"T3947","span":{"begin":3088,"end":3093},"obj":"DT"},{"id":"T3948","span":{"begin":3094,"end":3102},"obj":"NNS"},{"id":"T3949","span":{"begin":3103,"end":3106},"obj":"VBP"},{"id":"T3950","span":{"begin":3107,"end":3110},"obj":"RB"},{"id":"T3951","span":{"begin":3120,"end":3122},"obj":"TO"},{"id":"T3952","span":{"begin":3123,"end":3127},"obj":"VB"},{"id":"T3953","span":{"begin":3128,"end":3145},"obj":"NN"},{"id":"T3954","span":{"begin":3146,"end":3151},"obj":"NNS"},{"id":"T3955","span":{"begin":3152,"end":3155},"obj":"IN"},{"id":"T3956","span":{"begin":3156,"end":3159},"obj":"DT"},{"id":"T3957","span":{"begin":3160,"end":3164},"obj":"NN"},{"id":"T3958","span":{"begin":3165,"end":3167},"obj":"IN"},{"id":"T3959","span":{"begin":3168,"end":3173},"obj":"PRP$"},{"id":"T3960","span":{"begin":3174,"end":3179},"obj":"NNS"},{"id":"T3961","span":{"begin":3179,"end":3181},"obj":","},{"id":"T3962","span":{"begin":3181,"end":3186},"obj":"RB"},{"id":"T3963","span":{"begin":3187,"end":3191},"obj":"IN"},{"id":"T3964","span":{"begin":3192,"end":3203},"obj":"JJ"},{"id":"T3965","span":{"begin":3209,"end":3216},"obj":"NNS"},{"id":"T3966","span":{"begin":3204,"end":3208},"obj":"NN"},{"id":"T3967","span":{"begin":3216,"end":3217},"obj":"."},{"id":"T3968","span":{"begin":3217,"end":3394},"obj":"sentence"},{"id":"T3969","span":{"begin":3218,"end":3226},"obj":"RB"},{"id":"T3970","span":{"begin":3312,"end":3315},"obj":"VBP"},{"id":"T3971","span":{"begin":3226,"end":3228},"obj":","},{"id":"T3972","span":{"begin":3228,"end":3231},"obj":"DT"},{"id":"T3973","span":{"begin":3232,"end":3236},"obj":"NN"},{"id":"T3974","span":{"begin":3237,"end":3247},"obj":"VBN"},{"id":"T3975","span":{"begin":3248,"end":3252},"obj":"IN"},{"id":"T3976","span":{"begin":3253,"end":3258},"obj":"NN"},{"id":"T3977","span":{"begin":3259,"end":3274},"obj":"NN"},{"id":"T3978","span":{"begin":3275,"end":3278},"obj":"CC"},{"id":"T3979","span":{"begin":3279,"end":3282},"obj":"DT"},{"id":"T3980","span":{"begin":3283,"end":3295},"obj":"NN"},{"id":"T3981","span":{"begin":3296,"end":3298},"obj":"IN"},{"id":"T3982","span":{"begin":3299,"end":3304},"obj":"NN"},{"id":"T3983","span":{"begin":3305,"end":3311},"obj":"NNS"},{"id":"T3984","span":{"begin":3316,"end":3326},"obj":"JJ"},{"id":"T3985","span":{"begin":3336,"end":3343},"obj":"NNS"},{"id":"T3986","span":{"begin":3327,"end":3335},"obj":"VBG"},{"id":"T3987","span":{"begin":3344,"end":3347},"obj":"IN"},{"id":"T3988","span":{"begin":3348,"end":3351},"obj":"DT"},{"id":"T3989","span":{"begin":3352,"end":3364},"obj":"NN"},{"id":"T3990","span":{"begin":3365,"end":3367},"obj":"IN"},{"id":"T3991","span":{"begin":3368,"end":3377},"obj":"NN"},{"id":"T3992","span":{"begin":3378,"end":3380},"obj":"IN"},{"id":"T3993","span":{"begin":3381,"end":3385},"obj":"DT"},{"id":"T3994","span":{"begin":3386,"end":3393},"obj":"NN"},{"id":"T3995","span":{"begin":3393,"end":3394},"obj":"."},{"id":"T3996","span":{"begin":3394,"end":3530},"obj":"sentence"},{"id":"T3997","span":{"begin":3395,"end":3402},"obj":"IN"},{"id":"T3998","span":{"begin":3474,"end":3476},"obj":"VBZ"},{"id":"T3999","span":{"begin":3403,"end":3405},"obj":"IN"},{"id":"T4000","span":{"begin":3406,"end":3409},"obj":"DT"},{"id":"T4001","span":{"begin":3433,"end":3440},"obj":"NNS"},{"id":"T4002","span":{"begin":3410,"end":3417},"obj":"JJ"},{"id":"T4003","span":{"begin":3418,"end":3432},"obj":"JJ"},{"id":"T4004","span":{"begin":3441,"end":3444},"obj":"IN"},{"id":"T4005","span":{"begin":3445,"end":3448},"obj":"DT"},{"id":"T4006","span":{"begin":3449,"end":3458},"obj":"NN"},{"id":"T4007","span":{"begin":3459,"end":3461},"obj":"IN"},{"id":"T4008","span":{"begin":3462,"end":3466},"obj":"NN"},{"id":"T4009","span":{"begin":3466,"end":3468},"obj":","},{"id":"T4010","span":{"begin":3468,"end":3473},"obj":"EX"},{"id":"T4011","span":{"begin":3477,"end":3478},"obj":"DT"},{"id":"T4012","span":{"begin":3479,"end":3483},"obj":"NN"},{"id":"T4013","span":{"begin":3484,"end":3487},"obj":"IN"},{"id":"T4014","span":{"begin":3488,"end":3496},"obj":"VBN"},{"id":"T4015","span":{"begin":3497,"end":3506},"obj":"NNS"},{"id":"T4016","span":{"begin":3507,"end":3509},"obj":"TO"},{"id":"T4017","span":{"begin":3510,"end":3516},"obj":"VB"},{"id":"T4018","span":{"begin":3517,"end":3521},"obj":"DT"},{"id":"T4019","span":{"begin":3522,"end":3529},"obj":"NN"},{"id":"T4020","span":{"begin":3529,"end":3530},"obj":"."},{"id":"T4021","span":{"begin":3530,"end":3669},"obj":"sentence"},{"id":"T4022","span":{"begin":3531,"end":3533},"obj":"DT"},{"id":"T4023","span":{"begin":3534,"end":3542},"obj":"NN"},{"id":"T4024","span":{"begin":3587,"end":3591},"obj":"VBN"},{"id":"T4025","span":{"begin":3543,"end":3545},"obj":"IN"},{"id":"T4026","span":{"begin":3546,"end":3556},"obj":"VBG"},{"id":"T4027","span":{"begin":3557,"end":3562},"obj":"JJ"},{"id":"T4028","span":{"begin":3563,"end":3573},"obj":"NNS"},{"id":"T4029","span":{"begin":3574,"end":3577},"obj":"IN"},{"id":"T4030","span":{"begin":3578,"end":3582},"obj":"NN"},{"id":"T4031","span":{"begin":3583,"end":3586},"obj":"VBZ"},{"id":"T4032","span":{"begin":3592,"end":3595},"obj":"DT"},{"id":"T4033","span":{"begin":3596,"end":3600},"obj":"NN"},{"id":"T4034","span":{"begin":3601,"end":3603},"obj":"IN"},{"id":"T4035","span":{"begin":3604,"end":3605},"obj":"DT"},{"id":"T4036","span":{"begin":3622,"end":3627},"obj":"NN"},{"id":"T4037","span":{"begin":3606,"end":3614},"obj":"JJ"},{"id":"T4038","span":{"begin":3615,"end":3621},"obj":"NN"},{"id":"T4039","span":{"begin":3628,"end":3630},"obj":"TO"},{"id":"T4040","span":{"begin":3631,"end":3638},"obj":"VB"},{"id":"T4041","span":{"begin":3639,"end":3648},"obj":"JJ"},{"id":"T4042","span":{"begin":3661,"end":3668},"obj":"NNS"},{"id":"T4043","span":{"begin":3649,"end":3660},"obj":"JJ"},{"id":"T4044","span":{"begin":3668,"end":3669},"obj":"."},{"id":"T4045","span":{"begin":3669,"end":3824},"obj":"sentence"},{"id":"T4046","span":{"begin":3670,"end":3678},"obj":"IN"},{"id":"T4047","span":{"begin":3720,"end":3729},"obj":"VBN"},{"id":"T4048","span":{"begin":3679,"end":3680},"obj":"DT"},{"id":"T4049","span":{"begin":3695,"end":3700},"obj":"NN"},{"id":"T4050","span":{"begin":3681,"end":3689},"obj":"NNP"},{"id":"T4051","span":{"begin":3690,"end":3694},"obj":"NN"},{"id":"T4052","span":{"begin":3701,"end":3705},"obj":"IN"},{"id":"T4053","span":{"begin":3706,"end":3710},"obj":"NN"},{"id":"T4054","span":{"begin":3711,"end":3714},"obj":"VBZ"},{"id":"T4055","span":{"begin":3715,"end":3719},"obj":"VBN"},{"id":"T4056","span":{"begin":3750,"end":3752},"obj":"VBZ"},{"id":"T4057","span":{"begin":3730,"end":3731},"obj":"-LRB-"},{"id":"T4058","span":{"begin":3731,"end":3733},"obj":"CD"},{"id":"T4059","span":{"begin":3733,"end":3734},"obj":"SYM"},{"id":"T4060","span":{"begin":3734,"end":3736},"obj":"CD"},{"id":"T4061","span":{"begin":3736,"end":3737},"obj":"-RRB-"},{"id":"T4062","span":{"begin":3737,"end":3739},"obj":","},{"id":"T4063","span":{"begin":3739,"end":3743},"obj":"DT"},{"id":"T4064","span":{"begin":3744,"end":3749},"obj":"NN"},{"id":"T4065","span":{"begin":3753,"end":3760},"obj":"CC"},{"id":"T4066","span":{"begin":3769,"end":3778},"obj":"JJ"},{"id":"T4067","span":{"begin":3761,"end":3768},"obj":"RB"},{"id":"T4068","span":{"begin":3779,"end":3782},"obj":"CC"},{"id":"T4069","span":{"begin":3783,"end":3792},"obj":"JJ"},{"id":"T4070","span":{"begin":3793,"end":3795},"obj":"TO"},{"id":"T4071","span":{"begin":3796,"end":3803},"obj":"VB"},{"id":"T4072","span":{"begin":3804,"end":3815},"obj":"JJ"},{"id":"T4073","span":{"begin":3816,"end":3823},"obj":"NNS"},{"id":"T4074","span":{"begin":3823,"end":3824},"obj":"."},{"id":"T4075","span":{"begin":3824,"end":4014},"obj":"sentence"},{"id":"T4076","span":{"begin":3825,"end":3836},"obj":"RB"},{"id":"T4077","span":{"begin":3890,"end":3895},"obj":"VBN"},{"id":"T4078","span":{"begin":3836,"end":3838},"obj":","},{"id":"T4079","span":{"begin":3838,"end":3848},"obj":"NN"},{"id":"T4080","span":{"begin":3849,"end":3851},"obj":"IN"},{"id":"T4081","span":{"begin":3852,"end":3856},"obj":"DT"},{"id":"T4082","span":{"begin":3864,"end":3869},"obj":"NN"},{"id":"T4083","span":{"begin":3857,"end":3863},"obj":"NN"},{"id":"T4084","span":{"begin":3870,"end":3874},"obj":"IN"},{"id":"T4085","span":{"begin":3875,"end":3880},"obj":"JJ"},{"id":"T4086","span":{"begin":3881,"end":3885},"obj":"NN"},{"id":"T4087","span":{"begin":3886,"end":3889},"obj":"VBZ"},{"id":"T4088","span":{"begin":3896,"end":3900},"obj":"DT"},{"id":"T4089","span":{"begin":3901,"end":3912},"obj":"NNS"},{"id":"T4090","span":{"begin":3913,"end":3915},"obj":"IN"},{"id":"T4091","span":{"begin":3916,"end":3919},"obj":"DT"},{"id":"T4092","span":{"begin":3920,"end":3929},"obj":"NN"},{"id":"T4093","span":{"begin":3930,"end":3932},"obj":"IN"},{"id":"T4094","span":{"begin":3933,"end":3936},"obj":"DT"},{"id":"T4095","span":{"begin":3937,"end":3944},"obj":"NN"},{"id":"T4096","span":{"begin":3945,"end":3946},"obj":"-LRB-"},{"id":"T4097","span":{"begin":3946,"end":3947},"obj":"CD"},{"id":"T4098","span":{"begin":3947,"end":3948},"obj":"-RRB-"},{"id":"T4099","span":{"begin":3948,"end":3950},"obj":","},{"id":"T4100","span":{"begin":3950,"end":3956},"obj":"VBG"},{"id":"T4101","span":{"begin":3957,"end":3961},"obj":"DT"},{"id":"T4102","span":{"begin":3962,"end":3968},"obj":"NN"},{"id":"T4103","span":{"begin":3986,"end":3991},"obj":"NN"},{"id":"T4104","span":{"begin":3969,"end":3970},"obj":"DT"},{"id":"T4105","span":{"begin":3971,"end":3975},"obj":"RBR"},{"id":"T4106","span":{"begin":3976,"end":3985},"obj":"JJ"},{"id":"T4107","span":{"begin":3992,"end":3995},"obj":"IN"},{"id":"T4108","span":{"begin":3996,"end":3999},"obj":"DT"},{"id":"T4109","span":{"begin":4006,"end":4013},"obj":"NN"},{"id":"T4110","span":{"begin":4000,"end":4005},"obj":"JJ"},{"id":"T4111","span":{"begin":4013,"end":4014},"obj":"."},{"id":"T4112","span":{"begin":4014,"end":4141},"obj":"sentence"},{"id":"T4113","span":{"begin":4015,"end":4023},"obj":"RB"},{"id":"T4114","span":{"begin":4126,"end":4135},"obj":"VBN"},{"id":"T4115","span":{"begin":4023,"end":4025},"obj":","},{"id":"T4116","span":{"begin":4025,"end":4026},"obj":"DT"},{"id":"T4117","span":{"begin":4037,"end":4048},"obj":"NN"},{"id":"T4118","span":{"begin":4027,"end":4028},"obj":"NN"},{"id":"T4119","span":{"begin":4029,"end":4034},"obj":"NN"},{"id":"T4120","span":{"begin":4028,"end":4029},"obj":"HYPH"},{"id":"T4121","span":{"begin":4034,"end":4035},"obj":"HYPH"},{"id":"T4122","span":{"begin":4035,"end":4036},"obj":"NN"},{"id":"T4123","span":{"begin":4036,"end":4037},"obj":"HYPH"},{"id":"T4124","span":{"begin":4055,"end":4062},"obj":"VBN"},{"id":"T4125","span":{"begin":4049,"end":4050},"obj":"-LRB-"},{"id":"T4126","span":{"begin":4050,"end":4053},"obj":"NN"},{"id":"T4127","span":{"begin":4053,"end":4054},"obj":"-RRB-"},{"id":"T4128","span":{"begin":4054,"end":4055},"obj":"HYPH"},{"id":"T4129","span":{"begin":4070,"end":4075},"obj":"NN"},{"id":"T4130","span":{"begin":4063,"end":4069},"obj":"NN"},{"id":"T4131","span":{"begin":4076,"end":4080},"obj":"WDT"},{"id":"T4132","span":{"begin":4096,"end":4105},"obj":"VBZ"},{"id":"T4133","span":{"begin":4081,"end":4095},"obj":"RB"},{"id":"T4134","span":{"begin":4106,"end":4111},"obj":"JJ"},{"id":"T4135","span":{"begin":4112,"end":4116},"obj":"NN"},{"id":"T4136","span":{"begin":4117,"end":4120},"obj":"VBZ"},{"id":"T4137","span":{"begin":4121,"end":4125},"obj":"VBN"},{"id":"T4138","span":{"begin":4136,"end":4137},"obj":"-LRB-"},{"id":"T4139","span":{"begin":4137,"end":4139},"obj":"CD"},{"id":"T4140","span":{"begin":4139,"end":4140},"obj":"-RRB-"},{"id":"T4141","span":{"begin":4140,"end":4141},"obj":"."},{"id":"T4142","span":{"begin":4141,"end":4310},"obj":"sentence"},{"id":"T4143","span":{"begin":4142,"end":4149},"obj":"RB"},{"id":"T4144","span":{"begin":4178,"end":4186},"obj":"VBZ"},{"id":"T4145","span":{"begin":4149,"end":4151},"obj":","},{"id":"T4146","span":{"begin":4151,"end":4154},"obj":"DT"},{"id":"T4147","span":{"begin":4155,"end":4163},"obj":"NN"},{"id":"T4148","span":{"begin":4164,"end":4166},"obj":"IN"},{"id":"T4149","span":{"begin":4167,"end":4171},"obj":"DT"},{"id":"T4150","span":{"begin":4172,"end":4177},"obj":"NN"},{"id":"T4151","span":{"begin":4187,"end":4188},"obj":"DT"},{"id":"T4152","span":{"begin":4196,"end":4200},"obj":"NN"},{"id":"T4153","span":{"begin":4189,"end":4195},"obj":"NN"},{"id":"T4154","span":{"begin":4201,"end":4203},"obj":"IN"},{"id":"T4155","span":{"begin":4204,"end":4207},"obj":"DT"},{"id":"T4156","span":{"begin":4237,"end":4253},"obj":"NN"},{"id":"T4157","span":{"begin":4208,"end":4221},"obj":"JJ"},{"id":"T4158","span":{"begin":4222,"end":4230},"obj":"VBN"},{"id":"T4159","span":{"begin":4231,"end":4236},"obj":"NN"},{"id":"T4160","span":{"begin":4230,"end":4231},"obj":"HYPH"},{"id":"T4161","span":{"begin":4261,"end":4265},"obj":"NN"},{"id":"T4162","span":{"begin":4254,"end":4255},"obj":"-LRB-"},{"id":"T4163","span":{"begin":4255,"end":4259},"obj":"NN"},{"id":"T4164","span":{"begin":4259,"end":4260},"obj":"-RRB-"},{"id":"T4165","span":{"begin":4265,"end":4267},"obj":","},{"id":"T4166","span":{"begin":4267,"end":4270},"obj":"RB"},{"id":"T4167","span":{"begin":4271,"end":4273},"obj":"IN"},{"id":"T4168","span":{"begin":4274,"end":4279},"obj":"NN"},{"id":"T4169","span":{"begin":4279,"end":4281},"obj":","},{"id":"T4170","span":{"begin":4281,"end":4284},"obj":"DT"},{"id":"T4171","span":{"begin":4295,"end":4301},"obj":"NN"},{"id":"T4172","span":{"begin":4285,"end":4294},"obj":"JJ"},{"id":"T4173","span":{"begin":4302,"end":4304},"obj":"IN"},{"id":"T4174","span":{"begin":4305,"end":4309},"obj":"NN"},{"id":"T4175","span":{"begin":4309,"end":4310},"obj":"."},{"id":"T4176","span":{"begin":4310,"end":4428},"obj":"sentence"},{"id":"T4177","span":{"begin":4311,"end":4318},"obj":"IN"},{"id":"T4178","span":{"begin":4332,"end":4334},"obj":"VBZ"},{"id":"T4179","span":{"begin":4319,"end":4322},"obj":"DT"},{"id":"T4180","span":{"begin":4323,"end":4331},"obj":"NN"},{"id":"T4181","span":{"begin":4412,"end":4414},"obj":"VBZ"},{"id":"T4182","span":{"begin":4335,"end":4338},"obj":"RB"},{"id":"T4183","span":{"begin":4339,"end":4341},"obj":"IN"},{"id":"T4184","span":{"begin":4342,"end":4347},"obj":"NN"},{"id":"T4185","span":{"begin":4347,"end":4349},"obj":","},{"id":"T4186","span":{"begin":4349,"end":4352},"obj":"DT"},{"id":"T4187","span":{"begin":4353,"end":4361},"obj":"NN"},{"id":"T4188","span":{"begin":4362,"end":4364},"obj":"IN"},{"id":"T4189","span":{"begin":4365,"end":4369},"obj":"DT"},{"id":"T4190","span":{"begin":4383,"end":4387},"obj":"NN"},{"id":"T4191","span":{"begin":4370,"end":4376},"obj":"NN"},{"id":"T4192","span":{"begin":4377,"end":4382},"obj":"NN"},{"id":"T4193","span":{"begin":4388,"end":4391},"obj":"IN"},{"id":"T4194","span":{"begin":4392,"end":4400},"obj":"VBG"},{"id":"T4195","span":{"begin":4407,"end":4411},"obj":"NN"},{"id":"T4196","span":{"begin":4401,"end":4406},"obj":"JJ"},{"id":"T4197","span":{"begin":4415,"end":4427},"obj":"JJ"},{"id":"T4198","span":{"begin":4427,"end":4428},"obj":"."},{"id":"T4199","span":{"begin":4428,"end":4615},"obj":"sentence"},{"id":"T4200","span":{"begin":4429,"end":4432},"obj":"DT"},{"id":"T4201","span":{"begin":4433,"end":4442},"obj":"NN"},{"id":"T4202","span":{"begin":4464,"end":4467},"obj":"VBD"},{"id":"T4203","span":{"begin":4443,"end":4445},"obj":"IN"},{"id":"T4204","span":{"begin":4446,"end":4449},"obj":"DT"},{"id":"T4205","span":{"begin":4458,"end":4463},"obj":"NN"},{"id":"T4206","span":{"begin":4450,"end":4457},"obj":"JJ"},{"id":"T4207","span":{"begin":4468,"end":4470},"obj":"TO"},{"id":"T4208","span":{"begin":4471,"end":4477},"obj":"VB"},{"id":"T4209","span":{"begin":4478,"end":4489},"obj":"RB"},{"id":"T4210","span":{"begin":4490,"end":4500},"obj":"VBN"},{"id":"T4211","span":{"begin":4508,"end":4514},"obj":"NNS"},{"id":"T4212","span":{"begin":4501,"end":4507},"obj":"JJ"},{"id":"T4213","span":{"begin":4515,"end":4517},"obj":"IN"},{"id":"T4214","span":{"begin":4518,"end":4522},"obj":"NN"},{"id":"T4215","span":{"begin":4523,"end":4527},"obj":"WDT"},{"id":"T4216","span":{"begin":4528,"end":4533},"obj":"VBP"},{"id":"T4217","span":{"begin":4534,"end":4537},"obj":"DT"},{"id":"T4218","span":{"begin":4538,"end":4547},"obj":"NN"},{"id":"T4219","span":{"begin":4548,"end":4550},"obj":"IN"},{"id":"T4220","span":{"begin":4551,"end":4554},"obj":"DT"},{"id":"T4221","span":{"begin":4588,"end":4593},"obj":"NNS"},{"id":"T4222","span":{"begin":4555,"end":4562},"obj":"JJ"},{"id":"T4223","span":{"begin":4563,"end":4566},"obj":"CC"},{"id":"T4224","span":{"begin":4567,"end":4579},"obj":"JJ"},{"id":"T4225","span":{"begin":4580,"end":4587},"obj":"JJ"},{"id":"T4226","span":{"begin":4594,"end":4596},"obj":"IN"},{"id":"T4227","span":{"begin":4597,"end":4600},"obj":"DT"},{"id":"T4228","span":{"begin":4607,"end":4614},"obj":"NN"},{"id":"T4229","span":{"begin":4601,"end":4606},"obj":"JJ"},{"id":"T4230","span":{"begin":4614,"end":4615},"obj":"."},{"id":"T4231","span":{"begin":4615,"end":4755},"obj":"sentence"},{"id":"T4232","span":{"begin":4616,"end":4619},"obj":"DT"},{"id":"T4233","span":{"begin":4628,"end":4633},"obj":"NN"},{"id":"T4234","span":{"begin":4620,"end":4627},"obj":"JJ"},{"id":"T4235","span":{"begin":4638,"end":4645},"obj":"VBN"},{"id":"T4236","span":{"begin":4634,"end":4637},"obj":"VBD"},{"id":"T4237","span":{"begin":4646,"end":4648},"obj":"IN"},{"id":"T4238","span":{"begin":4649,"end":4657},"obj":"VBN"},{"id":"T4239","span":{"begin":4658,"end":4670},"obj":"NN"},{"id":"T4240","span":{"begin":4671,"end":4673},"obj":"IN"},{"id":"T4241","span":{"begin":4674,"end":4677},"obj":"DT"},{"id":"T4242","span":{"begin":4681,"end":4688},"obj":"NN"},{"id":"T4243","span":{"begin":4678,"end":4680},"obj":"NN"},{"id":"T4244","span":{"begin":4689,"end":4691},"obj":"IN"},{"id":"T4245","span":{"begin":4692,"end":4697},"obj":"NN"},{"id":"T4246","span":{"begin":4698,"end":4700},"obj":"IN"},{"id":"T4247","span":{"begin":4701,"end":4711},"obj":"JJ"},{"id":"T4248","span":{"begin":4712,"end":4725},"obj":"NN"},{"id":"T4249","span":{"begin":4726,"end":4728},"obj":"IN"},{"id":"T4250","span":{"begin":4729,"end":4738},"obj":"JJ"},{"id":"T4251","span":{"begin":4745,"end":4747},"obj":"NN"},{"id":"T4252","span":{"begin":4739,"end":4743},"obj":"NN"},{"id":"T4253","span":{"begin":4744,"end":4745},"obj":"-LRB-"},{"id":"T4254","span":{"begin":4749,"end":4754},"obj":"NNS"},{"id":"T4255","span":{"begin":4747,"end":4748},"obj":"-RRB-"},{"id":"T4256","span":{"begin":4754,"end":4755},"obj":"."},{"id":"T4257","span":{"begin":4755,"end":4852},"obj":"sentence"},{"id":"T4258","span":{"begin":4756,"end":4759},"obj":"DT"},{"id":"T4259","span":{"begin":4760,"end":4765},"obj":"NN"},{"id":"T4260","span":{"begin":4791,"end":4798},"obj":"VBN"},{"id":"T4261","span":{"begin":4766,"end":4768},"obj":"IN"},{"id":"T4262","span":{"begin":4769,"end":4781},"obj":"JJ"},{"id":"T4263","span":{"begin":4782,"end":4786},"obj":"NN"},{"id":"T4264","span":{"begin":4787,"end":4790},"obj":"VBD"},{"id":"T4265","span":{"begin":4799,"end":4801},"obj":"IN"},{"id":"T4266","span":{"begin":4802,"end":4809},"obj":"JJ"},{"id":"T4267","span":{"begin":4821,"end":4827},"obj":"NN"},{"id":"T4268","span":{"begin":4810,"end":4820},"obj":"JJ"},{"id":"T4269","span":{"begin":4828,"end":4830},"obj":"IN"},{"id":"T4270","span":{"begin":4831,"end":4834},"obj":"DT"},{"id":"T4271","span":{"begin":4843,"end":4851},"obj":"NN"},{"id":"T4272","span":{"begin":4835,"end":4837},"obj":"NN"},{"id":"T4273","span":{"begin":4838,"end":4842},"obj":"NN"},{"id":"T4274","span":{"begin":4851,"end":4852},"obj":"."},{"id":"T4275","span":{"begin":4852,"end":4942},"obj":"sentence"},{"id":"T4276","span":{"begin":4853,"end":4857},"obj":"DT"},{"id":"T4277","span":{"begin":4858,"end":4864},"obj":"NN"},{"id":"T4278","span":{"begin":4865,"end":4874},"obj":"VBZ"},{"id":"T4279","span":{"begin":4875,"end":4878},"obj":"DT"},{"id":"T4280","span":{"begin":4879,"end":4889},"obj":"NN"},{"id":"T4281","span":{"begin":4890,"end":4893},"obj":"CC"},{"id":"T4282","span":{"begin":4894,"end":4910},"obj":"NN"},{"id":"T4283","span":{"begin":4911,"end":4913},"obj":"IN"},{"id":"T4284","span":{"begin":4914,"end":4919},"obj":"DT"},{"id":"T4285","span":{"begin":4927,"end":4933},"obj":"NNS"},{"id":"T4286","span":{"begin":4920,"end":4926},"obj":"JJ"},{"id":"T4287","span":{"begin":4934,"end":4936},"obj":"IN"},{"id":"T4288","span":{"begin":4937,"end":4941},"obj":"NN"},{"id":"T4289","span":{"begin":4941,"end":4942},"obj":"."},{"id":"T4290","span":{"begin":4942,"end":5079},"obj":"sentence"},{"id":"T4291","span":{"begin":4943,"end":4948},"obj":"DT"},{"id":"T4292","span":{"begin":4949,"end":4955},"obj":"NNS"},{"id":"T4293","span":{"begin":4961,"end":4966},"obj":"VB"},{"id":"T4294","span":{"begin":4956,"end":4960},"obj":"MD"},{"id":"T4295","span":{"begin":4967,"end":4970},"obj":"IN"},{"id":"T4296","span":{"begin":4971,"end":4974},"obj":"DT"},{"id":"T4297","span":{"begin":4975,"end":4986},"obj":"NN"},{"id":"T4298","span":{"begin":4987,"end":4989},"obj":"IN"},{"id":"T4299","span":{"begin":4990,"end":4995},"obj":"JJ"},{"id":"T4300","span":{"begin":5006,"end":5016},"obj":"NNS"},{"id":"T4301","span":{"begin":4996,"end":5005},"obj":"NN"},{"id":"T4302","span":{"begin":5016,"end":5018},"obj":","},{"id":"T4303","span":{"begin":5018,"end":5022},"obj":"JJ"},{"id":"T4304","span":{"begin":5023,"end":5025},"obj":"IN"},{"id":"T4305","span":{"begin":5026,"end":5030},"obj":"NN"},{"id":"T4306","span":{"begin":5044,"end":5053},"obj":"NNS"},{"id":"T4307","span":{"begin":5031,"end":5033},"obj":"CC"},{"id":"T4308","span":{"begin":5034,"end":5038},"obj":"NN"},{"id":"T4309","span":{"begin":5039,"end":5043},"obj":"NN"},{"id":"T4310","span":{"begin":5053,"end":5055},"obj":","},{"id":"T4311","span":{"begin":5055,"end":5057},"obj":"TO"},{"id":"T4312","span":{"begin":5069,"end":5073},"obj":"VB"},{"id":"T4313","span":{"begin":5058,"end":5068},"obj":"RB"},{"id":"T4314","span":{"begin":5074,"end":5078},"obj":"NN"},{"id":"T4315","span":{"begin":5078,"end":5079},"obj":"."},{"id":"T3304","span":{"begin":11,"end":16},"obj":"NN"},{"id":"T3305","span":{"begin":17,"end":22},"obj":"NN"},{"id":"T3306","span":{"begin":29,"end":36},"obj":"NN"},{"id":"T3307","span":{"begin":23,"end":28},"obj":"NN"},{"id":"T3308","span":{"begin":44,"end":46},"obj":"VBZ"},{"id":"T3309","span":{"begin":37,"end":38},"obj":"-LRB-"},{"id":"T3310","span":{"begin":38,"end":42},"obj":"NN"},{"id":"T3311","span":{"begin":42,"end":43},"obj":"-RRB-"},{"id":"T3312","span":{"begin":47,"end":48},"obj":"DT"},{"id":"T3313","span":{"begin":57,"end":65},"obj":"NN"},{"id":"T3314","span":{"begin":49,"end":56},"obj":"JJ"},{"id":"T3315","span":{"begin":66,"end":72},"obj":"VBN"},{"id":"T3316","span":{"begin":73,"end":75},"obj":"IN"},{"id":"T3317","span":{"begin":76,"end":77},"obj":"DT"}],"relations":[{"id":"R348","pred":"compound","subj":"T3304","obj":"T3305"},{"id":"R349","pred":"compound","subj":"T3305","obj":"T3306"},{"id":"R350","pred":"nsubj","subj":"T3306","obj":"T3308"},{"id":"R351","pred":"compound","subj":"T3307","obj":"T3306"},{"id":"R352","pred":"punct","subj":"T3309","obj":"T3306"},{"id":"R353","pred":"appos","subj":"T3310","obj":"T3306"},{"id":"R354","pred":"punct","subj":"T3311","obj":"T3308"},{"id":"R355","pred":"det","subj":"T3312","obj":"T3313"},{"id":"R356","pred":"attr","subj":"T3313","obj":"T3308"},{"id":"R357","pred":"amod","subj":"T3314","obj":"T3313"},{"id":"R358","pred":"acl","subj":"T3315","obj":"T3313"},{"id":"R359","pred":"agent","subj":"T3316","obj":"T3315"},{"id":"R360","pred":"det","subj":"T3317","obj":"T3318"},{"id":"R361","pred":"pobj","subj":"T3318","obj":"T3316"},{"id":"R362","pred":"prep","subj":"T3319","obj":"T3318"},{"id":"R363","pred":"amod","subj":"T3320","obj":"T3321"},{"id":"R364","pred":"compound","subj":"T3321","obj":"T3323"},{"id":"R365","pred":"punct","subj":"T3322","obj":"T3321"},{"id":"R366","pred":"pobj","subj":"T3323","obj":"T3319"},{"id":"R367","pred":"compound","subj":"T3324","obj":"T3325"},{"id":"R368","pred":"compound","subj":"T3325","obj":"T3323"},{"id":"R369","pred":"punct","subj":"T3326","obj":"T3323"},{"id":"R370","pred":"appos","subj":"T3327","obj":"T3323"},{"id":"R371","pred":"punct","subj":"T3328","obj":"T3318"},{"id":"R372","pred":"punct","subj":"T3329","obj":"T3318"},{"id":"R373","pred":"det","subj":"T3330","obj":"T3331"},{"id":"R374","pred":"appos","subj":"T3331","obj":"T3318"},{"id":"R375","pred":"amod","subj":"T3332","obj":"T3331"},{"id":"R376","pred":"compound","subj":"T3333","obj":"T3331"},{"id":"R377","pred":"amod","subj":"T3334","obj":"T3331"},{"id":"R378","pred":"prep","subj":"T3335","obj":"T3334"},{"id":"R379","pred":"det","subj":"T3336","obj":"T3337"},{"id":"R380","pred":"pobj","subj":"T3337","obj":"T3335"},{"id":"R381","pred":"amod","subj":"T3338","obj":"T3337"},{"id":"R382","pred":"prep","subj":"T3339","obj":"T3337"},{"id":"R383","pred":"prep","subj":"T3423","obj":"T3422"},{"id":"R384","pred":"amod","subj":"T3340","obj":"T3341"},{"id":"R385","pred":"pobj","subj":"T3424","obj":"T3423"},{"id":"R386","pred":"punct","subj":"T3425","obj":"T3426"},{"id":"R387","pred":"compound","subj":"T3341","obj":"T3343"},{"id":"R388","pred":"parataxis","subj":"T3426","obj":"T3402"},{"id":"R389","pred":"punct","subj":"T3427","obj":"T3426"},{"id":"R390","pred":"punct","subj":"T3428","obj":"T3402"},{"id":"R391","pred":"det","subj":"T3430","obj":"T3431"},{"id":"R392","pred":"nsubj","subj":"T3431","obj":"T3432"},{"id":"R393","pred":"advmod","subj":"T3433","obj":"T3434"},{"id":"R394","pred":"amod","subj":"T3434","obj":"T3435"},{"id":"R395","pred":"dobj","subj":"T3435","obj":"T3432"},{"id":"R396","pred":"punct","subj":"T3342","obj":"T3341"},{"id":"R397","pred":"prep","subj":"T3436","obj":"T3435"},{"id":"R398","pred":"pobj","subj":"T3437","obj":"T3436"},{"id":"R399","pred":"prep","subj":"T3438","obj":"T3432"},{"id":"R400","pred":"pobj","subj":"T3439","obj":"T3438"},{"id":"R401","pred":"pobj","subj":"T3343","obj":"T3339"},{"id":"R402","pred":"cc","subj":"T3440","obj":"T3439"},{"id":"R403","pred":"amod","subj":"T3441","obj":"T3442"},{"id":"R404","pred":"compound","subj":"T3344","obj":"T3343"},{"id":"R405","pred":"conj","subj":"T3442","obj":"T3439"},{"id":"R406","pred":"compound","subj":"T3443","obj":"T3442"},{"id":"R407","pred":"punct","subj":"T3444","obj":"T3445"},{"id":"R408","pred":"acl","subj":"T3345","obj":"T3343"},{"id":"R409","pred":"parataxis","subj":"T3445","obj":"T3432"},{"id":"R410","pred":"punct","subj":"T3446","obj":"T3445"},{"id":"R411","pred":"punct","subj":"T3447","obj":"T3432"},{"id":"R412","pred":"prep","subj":"T3346","obj":"T3345"},{"id":"R413","pred":"prep","subj":"T3449","obj":"T3450"},{"id":"R414","pred":"amod","subj":"T3347","obj":"T3348"},{"id":"R415","pred":"det","subj":"T3451","obj":"T3452"},{"id":"R416","pred":"pobj","subj":"T3452","obj":"T3449"},{"id":"R417","pred":"compound","subj":"T3348","obj":"T3350"},{"id":"R418","pred":"amod","subj":"T3453","obj":"T3452"},{"id":"R419","pred":"punct","subj":"T3454","obj":"T3450"},{"id":"R420","pred":"expl","subj":"T3455","obj":"T3450"},{"id":"R421","pred":"punct","subj":"T3349","obj":"T3348"},{"id":"R422","pred":"amod","subj":"T3456","obj":"T3457"},{"id":"R423","pred":"pobj","subj":"T3350","obj":"T3346"},{"id":"R424","pred":"attr","subj":"T3457","obj":"T3450"},{"id":"R425","pred":"prep","subj":"T3458","obj":"T3457"},{"id":"R426","pred":"det","subj":"T3459","obj":"T3460"},{"id":"R427","pred":"pobj","subj":"T3460","obj":"T3458"},{"id":"R428","pred":"compound","subj":"T3351","obj":"T3350"},{"id":"R429","pred":"punct","subj":"T3461","obj":"T3450"},{"id":"R430","pred":"nsubj","subj":"T3463","obj":"T3464"},{"id":"R431","pred":"punct","subj":"T3352","obj":"T3350"},{"id":"R432","pred":"prep","subj":"T3465","obj":"T3463"},{"id":"R433","pred":"det","subj":"T3466","obj":"T3467"},{"id":"R434","pred":"appos","subj":"T3353","obj":"T3350"},{"id":"R435","pred":"punct","subj":"T3354","obj":"T3350"},{"id":"R436","pred":"pobj","subj":"T3467","obj":"T3465"},{"id":"R437","pred":"amod","subj":"T3468","obj":"T3467"},{"id":"R438","pred":"punct","subj":"T3355","obj":"T3350"},{"id":"R439","pred":"prep","subj":"T3469","obj":"T3467"},{"id":"R440","pred":"det","subj":"T3470","obj":"T3471"},{"id":"R441","pred":"pobj","subj":"T3471","obj":"T3469"},{"id":"R442","pred":"compound","subj":"T3472","obj":"T3473"},{"id":"R443","pred":"dobj","subj":"T3473","obj":"T3464"},{"id":"R444","pred":"prep","subj":"T3474","obj":"T3473"},{"id":"R445","pred":"conj","subj":"T3356","obj":"T3350"},{"id":"R446","pred":"det","subj":"T3475","obj":"T3476"},{"id":"R447","pred":"pobj","subj":"T3476","obj":"T3474"},{"id":"R448","pred":"prep","subj":"T3477","obj":"T3476"},{"id":"R449","pred":"punct","subj":"T3357","obj":"T3356"},{"id":"R450","pred":"quantmod","subj":"T3478","obj":"T3479"},{"id":"R451","pred":"nummod","subj":"T3479","obj":"T3481"},{"id":"R452","pred":"punct","subj":"T3480","obj":"T3479"},{"id":"R453","pred":"conj","subj":"T3358","obj":"T3356"},{"id":"R454","pred":"pobj","subj":"T3481","obj":"T3477"},{"id":"R455","pred":"prep","subj":"T3482","obj":"T3481"},{"id":"R456","pred":"pobj","subj":"T3483","obj":"T3482"},{"id":"R457","pred":"cc","subj":"T3359","obj":"T3358"},{"id":"R458","pred":"punct","subj":"T3484","obj":"T3464"},{"id":"R459","pred":"prep","subj":"T3486","obj":"T3487"},{"id":"R460","pred":"conj","subj":"T3360","obj":"T3358"},{"id":"R461","pred":"amod","subj":"T3488","obj":"T3489"},{"id":"R462","pred":"pobj","subj":"T3489","obj":"T3486"},{"id":"R463","pred":"punct","subj":"T3361","obj":"T3362"},{"id":"R464","pred":"det","subj":"T3490","obj":"T3491"},{"id":"R465","pred":"nsubjpass","subj":"T3491","obj":"T3487"},{"id":"R466","pred":"parataxis","subj":"T3362","obj":"T3308"},{"id":"R467","pred":"prep","subj":"T3492","obj":"T3491"},{"id":"R468","pred":"det","subj":"T3493","obj":"T3494"},{"id":"R469","pred":"pobj","subj":"T3494","obj":"T3492"},{"id":"R470","pred":"auxpass","subj":"T3495","obj":"T3487"},{"id":"R471","pred":"prep","subj":"T3363","obj":"T3362"},{"id":"R472","pred":"punct","subj":"T3496","obj":"T3487"},{"id":"R473","pred":"cc","subj":"T3497","obj":"T3487"},{"id":"R474","pred":"expl","subj":"T3498","obj":"T3499"},{"id":"R475","pred":"pobj","subj":"T3364","obj":"T3363"},{"id":"R476","pred":"conj","subj":"T3499","obj":"T3487"},{"id":"R477","pred":"punct","subj":"T3365","obj":"T3362"},{"id":"R478","pred":"advmod","subj":"T3500","obj":"T3501"},{"id":"R479","pred":"amod","subj":"T3501","obj":"T3502"},{"id":"R480","pred":"attr","subj":"T3502","obj":"T3499"},{"id":"R481","pred":"prep","subj":"T3503","obj":"T3502"},{"id":"R482","pred":"punct","subj":"T3366","obj":"T3362"},{"id":"R483","pred":"pobj","subj":"T3504","obj":"T3503"},{"id":"R484","pred":"punct","subj":"T3505","obj":"T3506"},{"id":"R485","pred":"punct","subj":"T3367","obj":"T3362"},{"id":"R486","pred":"parataxis","subj":"T3506","obj":"T3499"},{"id":"R487","pred":"punct","subj":"T3507","obj":"T3506"},{"id":"R488","pred":"punct","subj":"T3508","obj":"T3499"},{"id":"R489","pred":"dobj","subj":"T3368","obj":"T3362"},{"id":"R490","pred":"nsubj","subj":"T3510","obj":"T3511"},{"id":"R491","pred":"punct","subj":"T3369","obj":"T3362"},{"id":"R492","pred":"prep","subj":"T3512","obj":"T3510"},{"id":"R493","pred":"det","subj":"T3513","obj":"T3514"},{"id":"R494","pred":"pobj","subj":"T3514","obj":"T3512"},{"id":"R495","pred":"amod","subj":"T3515","obj":"T3514"},{"id":"R496","pred":"prep","subj":"T3516","obj":"T3514"},{"id":"R497","pred":"punct","subj":"T3370","obj":"T3362"},{"id":"R498","pred":"pobj","subj":"T3517","obj":"T3516"},{"id":"R499","pred":"compound","subj":"T3518","obj":"T3519"},{"id":"R500","pred":"dobj","subj":"T3519","obj":"T3511"},{"id":"R501","pred":"prep","subj":"T3520","obj":"T3511"},{"id":"R502","pred":"punct","subj":"T3371","obj":"T3308"},{"id":"R503","pred":"det","subj":"T3521","obj":"T3522"},{"id":"R504","pred":"pobj","subj":"T3522","obj":"T3520"},{"id":"R505","pred":"prep","subj":"T3523","obj":"T3522"},{"id":"R506","pred":"nsubj","subj":"T3373","obj":"T3374"},{"id":"R507","pred":"quantmod","subj":"T3524","obj":"T3525"},{"id":"R508","pred":"nummod","subj":"T3525","obj":"T3527"},{"id":"R509","pred":"punct","subj":"T3526","obj":"T3525"},{"id":"R510","pred":"pobj","subj":"T3527","obj":"T3523"},{"id":"R511","pred":"prep","subj":"T3375","obj":"T3373"},{"id":"R512","pred":"cc","subj":"T3528","obj":"T3511"},{"id":"R513","pred":"pobj","subj":"T3376","obj":"T3375"},{"id":"R514","pred":"punct","subj":"T3377","obj":"T3374"},{"id":"R515","pred":"prep","subj":"T3378","obj":"T3374"},{"id":"R516","pred":"prep","subj":"T3529","obj":"T3530"},{"id":"R517","pred":"conj","subj":"T3530","obj":"T3511"},{"id":"R518","pred":"prep","subj":"T3379","obj":"T3378"},{"id":"R519","pred":"det","subj":"T3531","obj":"T3532"},{"id":"R520","pred":"pobj","subj":"T3532","obj":"T3529"},{"id":"R521","pred":"det","subj":"T3380","obj":"T3381"},{"id":"R522","pred":"amod","subj":"T3533","obj":"T3532"},{"id":"R523","pred":"det","subj":"T3534","obj":"T3535"},{"id":"R524","pred":"nsubj","subj":"T3535","obj":"T3530"},{"id":"R525","pred":"pobj","subj":"T3381","obj":"T3379"},{"id":"R526","pred":"compound","subj":"T3536","obj":"T3535"},{"id":"R527","pred":"compound","subj":"T3537","obj":"T3535"},{"id":"R528","pred":"acomp","subj":"T3538","obj":"T3530"},{"id":"R529","pred":"punct","subj":"T3382","obj":"T3374"},{"id":"R530","pred":"punct","subj":"T3539","obj":"T3540"},{"id":"R531","pred":"parataxis","subj":"T3540","obj":"T3530"},{"id":"R532","pred":"amod","subj":"T3383","obj":"T3384"},{"id":"R533","pred":"punct","subj":"T3541","obj":"T3540"},{"id":"R534","pred":"punct","subj":"T3542","obj":"T3530"},{"id":"R535","pred":"dobj","subj":"T3384","obj":"T3374"},{"id":"R536","pred":"det","subj":"T3544","obj":"T3545"},{"id":"R537","pred":"nsubj","subj":"T3545","obj":"T3547"},{"id":"R538","pred":"amod","subj":"T3546","obj":"T3545"},{"id":"R539","pred":"prep","subj":"T3385","obj":"T3384"},{"id":"R540","pred":"prep","subj":"T3548","obj":"T3545"},{"id":"R541","pred":"compound","subj":"T3386","obj":"T3387"},{"id":"R542","pred":"pobj","subj":"T3549","obj":"T3548"},{"id":"R543","pred":"prep","subj":"T3550","obj":"T3545"},{"id":"R544","pred":"det","subj":"T3551","obj":"T3552"},{"id":"R545","pred":"pobj","subj":"T3552","obj":"T3550"},{"id":"R546","pred":"amod","subj":"T3553","obj":"T3552"},{"id":"R547","pred":"pobj","subj":"T3387","obj":"T3385"},{"id":"R548","pred":"nummod","subj":"T3554","obj":"T3555"},{"id":"R549","pred":"attr","subj":"T3555","obj":"T3547"},{"id":"R550","pred":"punct","subj":"T3556","obj":"T3555"},{"id":"R551","pred":"acl","subj":"T3388","obj":"T3387"},{"id":"R552","pred":"punct","subj":"T3557","obj":"T3558"},{"id":"R553","pred":"parataxis","subj":"T3558","obj":"T3547"},{"id":"R554","pred":"punct","subj":"T3559","obj":"T3558"},{"id":"R555","pred":"prep","subj":"T3389","obj":"T3388"},{"id":"R556","pred":"punct","subj":"T3560","obj":"T3547"},{"id":"R557","pred":"cc","subj":"T3561","obj":"T3547"},{"id":"R558","pred":"prep","subj":"T3562","obj":"T3563"},{"id":"R559","pred":"amod","subj":"T3390","obj":"T3391"},{"id":"R560","pred":"conj","subj":"T3563","obj":"T3547"},{"id":"R561","pred":"pobj","subj":"T3391","obj":"T3389"},{"id":"R562","pred":"amod","subj":"T3564","obj":"T3565"},{"id":"R563","pred":"pobj","subj":"T3565","obj":"T3562"},{"id":"R564","pred":"compound","subj":"T3566","obj":"T3565"},{"id":"R565","pred":"amod","subj":"T3392","obj":"T3391"},{"id":"R566","pred":"punct","subj":"T3567","obj":"T3565"},{"id":"R567","pred":"amod","subj":"T3568","obj":"T3569"},{"id":"R568","pred":"prep","subj":"T3569","obj":"T3565"},{"id":"R569","pred":"pobj","subj":"T3570","obj":"T3569"},{"id":"R570","pred":"amod","subj":"T3393","obj":"T3391"},{"id":"R571","pred":"prep","subj":"T3571","obj":"T3570"},{"id":"R572","pred":"pobj","subj":"T3572","obj":"T3571"},{"id":"R573","pred":"punct","subj":"T3394","obj":"T3395"},{"id":"R574","pred":"punct","subj":"T3573","obj":"T3563"},{"id":"R575","pred":"det","subj":"T3574","obj":"T3575"},{"id":"R576","pred":"nsubjpass","subj":"T3575","obj":"T3563"},{"id":"R577","pred":"auxpass","subj":"T3576","obj":"T3563"},{"id":"R578","pred":"parataxis","subj":"T3395","obj":"T3374"},{"id":"R579","pred":"aux","subj":"T3577","obj":"T3578"},{"id":"R580","pred":"xcomp","subj":"T3578","obj":"T3563"},{"id":"R581","pred":"punct","subj":"T3396","obj":"T3395"},{"id":"R582","pred":"prep","subj":"T3579","obj":"T3578"},{"id":"R583","pred":"amod","subj":"T3580","obj":"T3579"},{"id":"R584","pred":"prep","subj":"T3581","obj":"T3580"},{"id":"R585","pred":"punct","subj":"T3397","obj":"T3374"},{"id":"R586","pred":"nummod","subj":"T3582","obj":"T3583"},{"id":"R587","pred":"pobj","subj":"T3583","obj":"T3581"},{"id":"R588","pred":"punct","subj":"T3584","obj":"T3583"},{"id":"R589","pred":"advmod","subj":"T3399","obj":"T3400"},{"id":"R590","pred":"punct","subj":"T3585","obj":"T3586"},{"id":"R591","pred":"parataxis","subj":"T3586","obj":"T3563"},{"id":"R592","pred":"punct","subj":"T3587","obj":"T3586"},{"id":"R593","pred":"punct","subj":"T3588","obj":"T3563"},{"id":"R594","pred":"nummod","subj":"T3400","obj":"T3401"},{"id":"R595","pred":"det","subj":"T3590","obj":"T3591"},{"id":"R596","pred":"nsubj","subj":"T3401","obj":"T3402"},{"id":"R597","pred":"nsubj","subj":"T3591","obj":"T3593"},{"id":"R598","pred":"compound","subj":"T3592","obj":"T3591"},{"id":"R599","pred":"punct","subj":"T3594","obj":"T3591"},{"id":"R600","pred":"det","subj":"T3595","obj":"T3596"},{"id":"R601","pred":"appos","subj":"T3596","obj":"T3591"},{"id":"R602","pred":"prep","subj":"T3403","obj":"T3401"},{"id":"R603","pred":"amod","subj":"T3597","obj":"T3596"},{"id":"R604","pred":"prep","subj":"T3598","obj":"T3596"},{"id":"R605","pred":"pobj","subj":"T3599","obj":"T3598"},{"id":"R606","pred":"punct","subj":"T3600","obj":"T3593"},{"id":"R607","pred":"prep","subj":"T3601","obj":"T3593"},{"id":"R608","pred":"compound","subj":"T3404","obj":"T3405"},{"id":"R609","pred":"nummod","subj":"T3602","obj":"T3603"},{"id":"R610","pred":"pobj","subj":"T3603","obj":"T3601"},{"id":"R611","pred":"amod","subj":"T3604","obj":"T3603"},{"id":"R612","pred":"pobj","subj":"T3405","obj":"T3403"},{"id":"R613","pred":"punct","subj":"T3605","obj":"T3603"},{"id":"R614","pred":"det","subj":"T3606","obj":"T3607"},{"id":"R615","pred":"appos","subj":"T3607","obj":"T3603"},{"id":"R616","pred":"det","subj":"T3406","obj":"T3407"},{"id":"R617","pred":"punct","subj":"T3608","obj":"T3609"},{"id":"R618","pred":"parataxis","subj":"T3609","obj":"T3607"},{"id":"R619","pred":"punct","subj":"T3610","obj":"T3609"},{"id":"R620","pred":"dobj","subj":"T3407","obj":"T3402"},{"id":"R621","pred":"punct","subj":"T3611","obj":"T3607"},{"id":"R622","pred":"det","subj":"T3612","obj":"T3613"},{"id":"R623","pred":"amod","subj":"T3408","obj":"T3407"},{"id":"R624","pred":"conj","subj":"T3613","obj":"T3607"},{"id":"R625","pred":"compound","subj":"T3614","obj":"T3613"},{"id":"R626","pred":"punct","subj":"T3615","obj":"T3616"},{"id":"R627","pred":"prep","subj":"T3409","obj":"T3407"},{"id":"R628","pred":"parataxis","subj":"T3616","obj":"T3613"},{"id":"R629","pred":"punct","subj":"T3617","obj":"T3616"},{"id":"R630","pred":"punct","subj":"T3618","obj":"T3613"},{"id":"R631","pred":"det","subj":"T3410","obj":"T3411"},{"id":"R632","pred":"cc","subj":"T3619","obj":"T3613"},{"id":"R633","pred":"det","subj":"T3620","obj":"T3621"},{"id":"R634","pred":"conj","subj":"T3621","obj":"T3613"},{"id":"R635","pred":"compound","subj":"T3622","obj":"T3621"},{"id":"R636","pred":"pobj","subj":"T3411","obj":"T3409"},{"id":"R637","pred":"punct","subj":"T3623","obj":"T3624"},{"id":"R638","pred":"parataxis","subj":"T3624","obj":"T3621"},{"id":"R639","pred":"punct","subj":"T3625","obj":"T3624"},{"id":"R640","pred":"prep","subj":"T3412","obj":"T3407"},{"id":"R641","pred":"punct","subj":"T3626","obj":"T3593"},{"id":"R642","pred":"compound","subj":"T3413","obj":"T3414"},{"id":"R644","pred":"nsubj","subj":"T3629","obj":"T3631"},{"id":"R645","pred":"compound","subj":"T3630","obj":"T3629"},{"id":"R646","pred":"pobj","subj":"T3414","obj":"T3412"},{"id":"R647","pred":"det","subj":"T3632","obj":"T3633"},{"id":"R648","pred":"attr","subj":"T3633","obj":"T3631"},{"id":"R649","pred":"prep","subj":"T3415","obj":"T3414"},{"id":"R650","pred":"det","subj":"T3416","obj":"T3417"},{"id":"R651","pred":"acl","subj":"T3634","obj":"T3633"},{"id":"R652","pred":"pobj","subj":"T3417","obj":"T3415"},{"id":"R653","pred":"prep","subj":"T3635","obj":"T3634"},{"id":"R654","pred":"nummod","subj":"T3636","obj":"T3637"},{"id":"R655","pred":"nmod","subj":"T3637","obj":"T3638"},{"id":"R656","pred":"prep","subj":"T3418","obj":"T3417"},{"id":"R657","pred":"pobj","subj":"T3638","obj":"T3635"},{"id":"R658","pred":"cc","subj":"T3639","obj":"T3637"},{"id":"R659","pred":"quantmod","subj":"T3419","obj":"T3420"},{"id":"R660","pred":"nummod","subj":"T3640","obj":"T3641"},{"id":"R661","pred":"conj","subj":"T3641","obj":"T3637"},{"id":"R662","pred":"punct","subj":"T3642","obj":"T3643"},{"id":"R663","pred":"nummod","subj":"T3420","obj":"T3422"},{"id":"R664","pred":"parataxis","subj":"T3643","obj":"T3631"},{"id":"R665","pred":"punct","subj":"T3644","obj":"T3643"},{"id":"R666","pred":"punct","subj":"T3645","obj":"T3631"},{"id":"R667","pred":"punct","subj":"T3421","obj":"T3420"},{"id":"R668","pred":"det","subj":"T3647","obj":"T3648"},{"id":"R669","pred":"pobj","subj":"T3422","obj":"T3418"},{"id":"R670","pred":"nsubj","subj":"T3648","obj":"T3652"},{"id":"R671","pred":"nmod","subj":"T3649","obj":"T3648"},{"id":"R672","pred":"cc","subj":"T3650","obj":"T3649"},{"id":"R673","pred":"conj","subj":"T3739","obj":"T3737"},{"id":"R674","pred":"conj","subj":"T3651","obj":"T3649"},{"id":"R675","pred":"acomp","subj":"T3653","obj":"T3652"},{"id":"R676","pred":"prep","subj":"T3654","obj":"T3653"},{"id":"R677","pred":"pobj","subj":"T3655","obj":"T3654"},{"id":"R678","pred":"prep","subj":"T3740","obj":"T3736"},{"id":"R679","pred":"punct","subj":"T3656","obj":"T3652"},{"id":"R680","pred":"mark","subj":"T3657","obj":"T3658"},{"id":"R681","pred":"advcl","subj":"T3658","obj":"T3652"},{"id":"R682","pred":"pobj","subj":"T3741","obj":"T3740"},{"id":"R683","pred":"nsubjpass","subj":"T3659","obj":"T3658"},{"id":"R684","pred":"auxpass","subj":"T3660","obj":"T3658"},{"id":"R685","pred":"advmod","subj":"T3661","obj":"T3658"},{"id":"R686","pred":"aux","subj":"T3742","obj":"T3730"},{"id":"R687","pred":"agent","subj":"T3662","obj":"T3658"},{"id":"R688","pred":"nmod","subj":"T3663","obj":"T3664"},{"id":"R689","pred":"pobj","subj":"T3664","obj":"T3662"},{"id":"R690","pred":"auxpass","subj":"T3743","obj":"T3730"},{"id":"R691","pred":"cc","subj":"T3665","obj":"T3663"},{"id":"R692","pred":"compound","subj":"T3666","obj":"T3667"},{"id":"R693","pred":"punct","subj":"T3745","obj":"T3744"},{"id":"R694","pred":"conj","subj":"T3667","obj":"T3663"},{"id":"R695","pred":"punct","subj":"T3668","obj":"T3667"},{"id":"R696","pred":"compound","subj":"T3669","obj":"T3664"},{"id":"R697","pred":"punct","subj":"T3670","obj":"T3671"},{"id":"R698","pred":"parataxis","subj":"T3671","obj":"T3664"},{"id":"R699","pred":"advmod","subj":"T3746","obj":"T3744"},{"id":"R700","pred":"punct","subj":"T3672","obj":"T3671"},{"id":"R701","pred":"cc","subj":"T3673","obj":"T3664"},{"id":"R702","pred":"det","subj":"T3674","obj":"T3675"},{"id":"R703","pred":"conj","subj":"T3675","obj":"T3664"},{"id":"R704","pred":"compound","subj":"T3676","obj":"T3677"},{"id":"R705","pred":"compound","subj":"T3677","obj":"T3675"},{"id":"R706","pred":"punct","subj":"T3678","obj":"T3679"},{"id":"R707","pred":"punct","subj":"T3747","obj":"T3744"},{"id":"R708","pred":"parataxis","subj":"T3679","obj":"T3675"},{"id":"R709","pred":"punct","subj":"T3680","obj":"T3679"},{"id":"R710","pred":"punct","subj":"T3681","obj":"T3652"},{"id":"R711","pred":"det","subj":"T3748","obj":"T3749"},{"id":"R712","pred":"nsubjpass","subj":"T3683","obj":"T3684"},{"id":"R713","pred":"nsubj","subj":"T3749","obj":"T3744"},{"id":"R714","pred":"auxpass","subj":"T3685","obj":"T3684"},{"id":"R715","pred":"advmod","subj":"T3686","obj":"T3684"},{"id":"R716","pred":"prep","subj":"T3750","obj":"T3749"},{"id":"R717","pred":"prep","subj":"T3687","obj":"T3684"},{"id":"R718","pred":"nummod","subj":"T3688","obj":"T3689"},{"id":"R719","pred":"pobj","subj":"T3689","obj":"T3687"},{"id":"R720","pred":"compound","subj":"T3751","obj":"T3752"},{"id":"R721","pred":"amod","subj":"T3690","obj":"T3689"},{"id":"R722","pred":"punct","subj":"T3691","obj":"T3689"},{"id":"R723","pred":"det","subj":"T3692","obj":"T3693"},{"id":"R724","pred":"appos","subj":"T3693","obj":"T3689"},{"id":"R725","pred":"pobj","subj":"T3752","obj":"T3750"},{"id":"R726","pred":"amod","subj":"T3694","obj":"T3693"},{"id":"R727","pred":"cc","subj":"T3695","obj":"T3693"},{"id":"R728","pred":"acl","subj":"T3753","obj":"T3752"},{"id":"R729","pred":"det","subj":"T3696","obj":"T3697"},{"id":"R730","pred":"conj","subj":"T3697","obj":"T3693"},{"id":"R731","pred":"dep","subj":"T3698","obj":"T3699"},{"id":"R732","pred":"relcl","subj":"T3699","obj":"T3689"},{"id":"R733","pred":"advmod","subj":"T3754","obj":"T3755"},{"id":"R734","pred":"det","subj":"T3700","obj":"T3701"},{"id":"R735","pred":"dobj","subj":"T3701","obj":"T3699"},{"id":"R736","pred":"prep","subj":"T3702","obj":"T3701"},{"id":"R737","pred":"advmod","subj":"T3755","obj":"T3753"},{"id":"R738","pred":"det","subj":"T3703","obj":"T3704"},{"id":"R739","pred":"pobj","subj":"T3704","obj":"T3702"},{"id":"R740","pred":"prep","subj":"T3705","obj":"T3699"},{"id":"R741","pred":"prep","subj":"T3756","obj":"T3744"},{"id":"R742","pred":"det","subj":"T3706","obj":"T3707"},{"id":"R743","pred":"pobj","subj":"T3707","obj":"T3705"},{"id":"R744","pred":"det","subj":"T3757","obj":"T3758"},{"id":"R745","pred":"nmod","subj":"T3708","obj":"T3707"},{"id":"R746","pred":"punct","subj":"T3709","obj":"T3710"},{"id":"R747","pred":"parataxis","subj":"T3710","obj":"T3708"},{"id":"R748","pred":"pobj","subj":"T3758","obj":"T3756"},{"id":"R749","pred":"punct","subj":"T3711","obj":"T3710"},{"id":"R750","pred":"cc","subj":"T3712","obj":"T3708"},{"id":"R751","pred":"conj","subj":"T3713","obj":"T3708"},{"id":"R752","pred":"compound","subj":"T3759","obj":"T3758"},{"id":"R753","pred":"punct","subj":"T3714","obj":"T3715"},{"id":"R754","pred":"parataxis","subj":"T3715","obj":"T3713"},{"id":"R755","pred":"punct","subj":"T3716","obj":"T3715"},{"id":"R756","pred":"prep","subj":"T3717","obj":"T3707"},{"id":"R757","pred":"det","subj":"T3718","obj":"T3719"},{"id":"R758","pred":"pobj","subj":"T3719","obj":"T3717"},{"id":"R759","pred":"punct","subj":"T3760","obj":"T3761"},{"id":"R760","pred":"compound","subj":"T3720","obj":"T3719"},{"id":"R761","pred":"compound","subj":"T3721","obj":"T3719"},{"id":"R762","pred":"punct","subj":"T3722","obj":"T3723"},{"id":"R763","pred":"parataxis","subj":"T3761","obj":"T3744"},{"id":"R764","pred":"parataxis","subj":"T3723","obj":"T3684"},{"id":"R765","pred":"nummod","subj":"T3762","obj":"T3761"},{"id":"R766","pred":"nummod","subj":"T3724","obj":"T3723"},{"id":"R767","pred":"punct","subj":"T3725","obj":"T3723"},{"id":"R768","pred":"punct","subj":"T3726","obj":"T3723"},{"id":"R769","pred":"punct","subj":"T3763","obj":"T3761"},{"id":"R770","pred":"punct","subj":"T3727","obj":"T3684"},{"id":"R771","pred":"punct","subj":"T3764","obj":"T3761"},{"id":"R772","pred":"punct","subj":"T3765","obj":"T3744"},{"id":"R773","pred":"prep","subj":"T3767","obj":"T3768"},{"id":"R774","pred":"nsubjpass","subj":"T3729","obj":"T3730"},{"id":"R775","pred":"ccomp","subj":"T3730","obj":"T3744"},{"id":"R776","pred":"prep","subj":"T3731","obj":"T3729"},{"id":"R777","pred":"pobj","subj":"T3769","obj":"T3767"},{"id":"R778","pred":"det","subj":"T3732","obj":"T3733"},{"id":"R779","pred":"pobj","subj":"T3733","obj":"T3731"},{"id":"R780","pred":"prep","subj":"T3734","obj":"T3733"},{"id":"R781","pred":"det","subj":"T3735","obj":"T3736"},{"id":"R782","pred":"punct","subj":"T3770","obj":"T3768"},{"id":"R783","pred":"pobj","subj":"T3736","obj":"T3734"},{"id":"R784","pred":"nmod","subj":"T3737","obj":"T3736"},{"id":"R785","pred":"cc","subj":"T3738","obj":"T3737"},{"id":"R786","pred":"nsubjpass","subj":"T3771","obj":"T3768"},{"id":"R787","pred":"prep","subj":"T3772","obj":"T3771"},{"id":"R788","pred":"pobj","subj":"T3773","obj":"T3772"},{"id":"R789","pred":"pobj","subj":"T3845","obj":"T3843"},{"id":"R790","pred":"aux","subj":"T3774","obj":"T3768"},{"id":"R791","pred":"prep","subj":"T3846","obj":"T3845"},{"id":"R792","pred":"amod","subj":"T3847","obj":"T3848"},{"id":"R793","pred":"neg","subj":"T3775","obj":"T3768"},{"id":"R794","pred":"pobj","subj":"T3848","obj":"T3846"},{"id":"R795","pred":"punct","subj":"T3849","obj":"T3844"},{"id":"R796","pred":"expl","subj":"T3850","obj":"T3844"},{"id":"R797","pred":"auxpass","subj":"T3776","obj":"T3768"},{"id":"R798","pred":"amod","subj":"T3851","obj":"T3852"},{"id":"R799","pred":"attr","subj":"T3852","obj":"T3844"},{"id":"R800","pred":"prep","subj":"T3777","obj":"T3768"},{"id":"R801","pred":"acl","subj":"T3853","obj":"T3852"},{"id":"R802","pred":"prep","subj":"T3854","obj":"T3853"},{"id":"R803","pred":"pobj","subj":"T3778","obj":"T3777"},{"id":"R804","pred":"pobj","subj":"T3855","obj":"T3854"},{"id":"R805","pred":"cc","subj":"T3856","obj":"T3844"},{"id":"R806","pred":"expl","subj":"T3857","obj":"T3858"},{"id":"R807","pred":"conj","subj":"T3858","obj":"T3844"},{"id":"R808","pred":"det","subj":"T3859","obj":"T3860"},{"id":"R809","pred":"attr","subj":"T3860","obj":"T3858"},{"id":"R810","pred":"prep","subj":"T3779","obj":"T3778"},{"id":"R811","pred":"amod","subj":"T3861","obj":"T3860"},{"id":"R812","pred":"prep","subj":"T3862","obj":"T3860"},{"id":"R813","pred":"amod","subj":"T3863","obj":"T3864"},{"id":"R814","pred":"pobj","subj":"T3864","obj":"T3862"},{"id":"R815","pred":"det","subj":"T3780","obj":"T3781"},{"id":"R816","pred":"prep","subj":"T3865","obj":"T3858"},{"id":"R817","pred":"pobj","subj":"T3866","obj":"T3865"},{"id":"R818","pred":"punct","subj":"T3867","obj":"T3868"},{"id":"R819","pred":"pobj","subj":"T3781","obj":"T3779"},{"id":"R820","pred":"parataxis","subj":"T3868","obj":"T3858"},{"id":"R821","pred":"punct","subj":"T3869","obj":"T3868"},{"id":"R822","pred":"punct","subj":"T3870","obj":"T3844"},{"id":"R823","pred":"amod","subj":"T3782","obj":"T3781"},{"id":"R824","pred":"prep","subj":"T3872","obj":"T3873"},{"id":"R825","pred":"cc","subj":"T3783","obj":"T3781"},{"id":"R826","pred":"pcomp","subj":"T3874","obj":"T3872"},{"id":"R827","pred":"det","subj":"T3875","obj":"T3876"},{"id":"R828","pred":"conj","subj":"T3784","obj":"T3781"},{"id":"R829","pred":"pobj","subj":"T3876","obj":"T3872"},{"id":"R830","pred":"amod","subj":"T3877","obj":"T3876"},{"id":"R831","pred":"prep","subj":"T3878","obj":"T3876"},{"id":"R832","pred":"punct","subj":"T3785","obj":"T3786"},{"id":"R833","pred":"det","subj":"T3879","obj":"T3880"},{"id":"R834","pred":"pobj","subj":"T3880","obj":"T3878"},{"id":"R835","pred":"prep","subj":"T3881","obj":"T3876"},{"id":"R836","pred":"parataxis","subj":"T3786","obj":"T3768"},{"id":"R837","pred":"compound","subj":"T3882","obj":"T3883"},{"id":"R838","pred":"compound","subj":"T3883","obj":"T3884"},{"id":"R839","pred":"pobj","subj":"T3884","obj":"T3881"},{"id":"R840","pred":"punct","subj":"T3787","obj":"T3786"},{"id":"R841","pred":"cc","subj":"T3885","obj":"T3876"},{"id":"R842","pred":"amod","subj":"T3886","obj":"T3887"},{"id":"R843","pred":"amod","subj":"T3887","obj":"T3889"},{"id":"R844","pred":"punct","subj":"T3788","obj":"T3768"},{"id":"R845","pred":"punct","subj":"T3888","obj":"T3887"},{"id":"R846","pred":"conj","subj":"T3889","obj":"T3876"},{"id":"R847","pred":"prep","subj":"T3890","obj":"T3889"},{"id":"R848","pred":"amod","subj":"T3790","obj":"T3791"},{"id":"R849","pred":"compound","subj":"T3891","obj":"T3892"},{"id":"R850","pred":"pobj","subj":"T3892","obj":"T3890"},{"id":"R851","pred":"prep","subj":"T3893","obj":"T3892"},{"id":"R852","pred":"amod","subj":"T3894","obj":"T3895"},{"id":"R853","pred":"nsubj","subj":"T3791","obj":"T3792"},{"id":"R854","pred":"pobj","subj":"T3895","obj":"T3893"},{"id":"R855","pred":"prep","subj":"T3793","obj":"T3791"},{"id":"R856","pred":"punct","subj":"T3896","obj":"T3897"},{"id":"R857","pred":"compound","subj":"T3794","obj":"T3795"},{"id":"R858","pred":"parataxis","subj":"T3897","obj":"T3889"},{"id":"R859","pred":"punct","subj":"T3898","obj":"T3899"},{"id":"R860","pred":"prep","subj":"T3899","obj":"T3897"},{"id":"R861","pred":"punct","subj":"T3900","obj":"T3897"},{"id":"R862","pred":"punct","subj":"T3901","obj":"T3873"},{"id":"R863","pred":"det","subj":"T3902","obj":"T3903"},{"id":"R864","pred":"pobj","subj":"T3795","obj":"T3793"},{"id":"R865","pred":"nsubjpass","subj":"T3903","obj":"T3873"},{"id":"R866","pred":"amod","subj":"T3904","obj":"T3903"},{"id":"R867","pred":"prep","subj":"T3796","obj":"T3792"},{"id":"R868","pred":"prep","subj":"T3905","obj":"T3903"},{"id":"R869","pred":"pobj","subj":"T3906","obj":"T3905"},{"id":"R870","pred":"aux","subj":"T3907","obj":"T3873"},{"id":"R871","pred":"det","subj":"T3797","obj":"T3798"},{"id":"R872","pred":"advmod","subj":"T3908","obj":"T3873"},{"id":"R873","pred":"auxpass","subj":"T3909","obj":"T3873"},{"id":"R874","pred":"prep","subj":"T3910","obj":"T3873"},{"id":"R875","pred":"pobj","subj":"T3798","obj":"T3796"},{"id":"R876","pred":"compound","subj":"T3911","obj":"T3912"},{"id":"R877","pred":"amod","subj":"T3799","obj":"T3798"},{"id":"R878","pred":"pobj","subj":"T3912","obj":"T3910"},{"id":"R879","pred":"amod","subj":"T3800","obj":"T3798"},{"id":"R880","pred":"punct","subj":"T3913","obj":"T3914"},{"id":"R881","pred":"amod","subj":"T3801","obj":"T3798"},{"id":"R882","pred":"parataxis","subj":"T3914","obj":"T3873"},{"id":"R883","pred":"punct","subj":"T3915","obj":"T3916"},{"id":"R884","pred":"prep","subj":"T3916","obj":"T3914"},{"id":"R885","pred":"prep","subj":"T3802","obj":"T3798"},{"id":"R886","pred":"punct","subj":"T3917","obj":"T3914"},{"id":"R887","pred":"punct","subj":"T3918","obj":"T3873"},{"id":"R888","pred":"pobj","subj":"T3803","obj":"T3802"},{"id":"R889","pred":"mark","subj":"T3920","obj":"T3921"},{"id":"R890","pred":"advcl","subj":"T3921","obj":"T3930"},{"id":"R891","pred":"det","subj":"T3922","obj":"T3923"},{"id":"R892","pred":"cc","subj":"T3804","obj":"T3803"},{"id":"R893","pred":"nsubj","subj":"T3923","obj":"T3921"},{"id":"R894","pred":"amod","subj":"T3924","obj":"T3925"},{"id":"R895","pred":"compound","subj":"T3925","obj":"T3923"},{"id":"R896","pred":"conj","subj":"T3805","obj":"T3803"},{"id":"R897","pred":"punct","subj":"T3926","obj":"T3925"},{"id":"R898","pred":"prep","subj":"T3927","obj":"T3923"},{"id":"R899","pred":"compound","subj":"T3928","obj":"T3929"},{"id":"R900","pred":"punct","subj":"T3806","obj":"T3807"},{"id":"R901","pred":"pobj","subj":"T3929","obj":"T3927"},{"id":"R902","pred":"acomp","subj":"T3931","obj":"T3921"},{"id":"R903","pred":"parataxis","subj":"T3807","obj":"T3792"},{"id":"R904","pred":"punct","subj":"T3932","obj":"T3930"},{"id":"R905","pred":"amod","subj":"T3933","obj":"T3934"},{"id":"R906","pred":"compound","subj":"T3934","obj":"T3936"},{"id":"R907","pred":"nummod","subj":"T3808","obj":"T3807"},{"id":"R908","pred":"punct","subj":"T3935","obj":"T3934"},{"id":"R909","pred":"nsubjpass","subj":"T3936","obj":"T3930"},{"id":"R910","pred":"punct","subj":"T3809","obj":"T3807"},{"id":"R911","pred":"prep","subj":"T3937","obj":"T3936"},{"id":"R912","pred":"det","subj":"T3938","obj":"T3939"},{"id":"R913","pred":"pobj","subj":"T3939","obj":"T3937"},{"id":"R914","pred":"auxpass","subj":"T3940","obj":"T3930"},{"id":"R915","pred":"neg","subj":"T3941","obj":"T3930"},{"id":"R916","pred":"punct","subj":"T3942","obj":"T3930"},{"id":"R917","pred":"punct","subj":"T3810","obj":"T3807"},{"id":"R918","pred":"advmod","subj":"T3944","obj":"T3945"},{"id":"R919","pred":"punct","subj":"T3946","obj":"T3945"},{"id":"R920","pred":"punct","subj":"T3811","obj":"T3792"},{"id":"R921","pred":"det","subj":"T3947","obj":"T3948"},{"id":"R922","pred":"nsubjpass","subj":"T3948","obj":"T3945"},{"id":"R923","pred":"auxpass","subj":"T3949","obj":"T3945"},{"id":"R924","pred":"predet","subj":"T3813","obj":"T3814"},{"id":"R925","pred":"advmod","subj":"T3950","obj":"T3945"},{"id":"R926","pred":"nsubj","subj":"T3814","obj":"T3817"},{"id":"R927","pred":"det","subj":"T3815","obj":"T3814"},{"id":"R928","pred":"aux","subj":"T3951","obj":"T3952"},{"id":"R929","pred":"xcomp","subj":"T3952","obj":"T3945"},{"id":"R930","pred":"compound","subj":"T3953","obj":"T3954"},{"id":"R931","pred":"amod","subj":"T3816","obj":"T3814"},{"id":"R932","pred":"dobj","subj":"T3954","obj":"T3952"},{"id":"R933","pred":"prep","subj":"T3955","obj":"T3952"},{"id":"R934","pred":"prep","subj":"T3818","obj":"T3814"},{"id":"R935","pred":"det","subj":"T3956","obj":"T3957"},{"id":"R936","pred":"pobj","subj":"T3957","obj":"T3955"},{"id":"R937","pred":"prep","subj":"T3958","obj":"T3957"},{"id":"R938","pred":"poss","subj":"T3959","obj":"T3960"},{"id":"R939","pred":"det","subj":"T3819","obj":"T3820"},{"id":"R940","pred":"pobj","subj":"T3960","obj":"T3958"},{"id":"R941","pred":"punct","subj":"T3961","obj":"T3952"},{"id":"R942","pred":"advmod","subj":"T3962","obj":"T3963"},{"id":"R943","pred":"pobj","subj":"T3820","obj":"T3818"},{"id":"R944","pred":"prep","subj":"T3963","obj":"T3952"},{"id":"R945","pred":"amod","subj":"T3964","obj":"T3965"},{"id":"R946","pred":"pobj","subj":"T3965","obj":"T3963"},{"id":"R947","pred":"punct","subj":"T3821","obj":"T3817"},{"id":"R948","pred":"compound","subj":"T3966","obj":"T3965"},{"id":"R949","pred":"punct","subj":"T3967","obj":"T3945"},{"id":"R950","pred":"advmod","subj":"T3822","obj":"T3817"},{"id":"R951","pred":"advmod","subj":"T3969","obj":"T3970"},{"id":"R952","pred":"punct","subj":"T3823","obj":"T3817"},{"id":"R953","pred":"punct","subj":"T3971","obj":"T3970"},{"id":"R954","pred":"det","subj":"T3972","obj":"T3973"},{"id":"R955","pred":"nsubj","subj":"T3973","obj":"T3970"},{"id":"R956","pred":"neg","subj":"T3824","obj":"T3817"},{"id":"R957","pred":"acl","subj":"T3974","obj":"T3973"},{"id":"R958","pred":"prep","subj":"T3975","obj":"T3974"},{"id":"R959","pred":"compound","subj":"T3976","obj":"T3977"},{"id":"R960","pred":"advmod","subj":"T3825","obj":"T3826"},{"id":"R961","pred":"pobj","subj":"T3977","obj":"T3975"},{"id":"R962","pred":"cc","subj":"T3978","obj":"T3973"},{"id":"R963","pred":"det","subj":"T3979","obj":"T3980"},{"id":"R964","pred":"conj","subj":"T3980","obj":"T3973"},{"id":"R965","pred":"prep","subj":"T3981","obj":"T3980"},{"id":"R966","pred":"acomp","subj":"T3826","obj":"T3817"},{"id":"R967","pred":"advmod","subj":"T3827","obj":"T3828"},{"id":"R968","pred":"compound","subj":"T3982","obj":"T3983"},{"id":"R969","pred":"prep","subj":"T3828","obj":"T3817"},{"id":"R970","pred":"pobj","subj":"T3983","obj":"T3981"},{"id":"R971","pred":"amod","subj":"T3984","obj":"T3985"},{"id":"R972","pred":"pobj","subj":"T3829","obj":"T3828"},{"id":"R973","pred":"attr","subj":"T3985","obj":"T3970"},{"id":"R974","pred":"amod","subj":"T3986","obj":"T3985"},{"id":"R975","pred":"prep","subj":"T3987","obj":"T3985"},{"id":"R976","pred":"prep","subj":"T3830","obj":"T3829"},{"id":"R977","pred":"det","subj":"T3988","obj":"T3989"},{"id":"R978","pred":"pobj","subj":"T3989","obj":"T3987"},{"id":"R979","pred":"prep","subj":"T3990","obj":"T3989"},{"id":"R980","pred":"amod","subj":"T3831","obj":"T3832"},{"id":"R981","pred":"pobj","subj":"T3991","obj":"T3990"},{"id":"R982","pred":"prep","subj":"T3992","obj":"T3991"},{"id":"R983","pred":"pobj","subj":"T3832","obj":"T3830"},{"id":"R984","pred":"det","subj":"T3993","obj":"T3994"},{"id":"R985","pred":"pobj","subj":"T3994","obj":"T3992"},{"id":"R986","pred":"prep","subj":"T3833","obj":"T3832"},{"id":"R989","pred":"pcomp","subj":"T3834","obj":"T3833"},{"id":"R990","pred":"pcomp","subj":"T3999","obj":"T3997"},{"id":"R991","pred":"pobj","subj":"T3835","obj":"T3833"},{"id":"R992","pred":"det","subj":"T4000","obj":"T4001"},{"id":"R994","pred":"punct","subj":"T3836","obj":"T3835"},{"id":"R995","pred":"amod","subj":"T4002","obj":"T4001"},{"id":"R996","pred":"amod","subj":"T4003","obj":"T4001"},{"id":"R997","pred":"prep","subj":"T4004","obj":"T4001"},{"id":"R998","pred":"det","subj":"T4005","obj":"T4006"},{"id":"R999","pred":"conj","subj":"T3837","obj":"T3835"},{"id":"R1000","pred":"pobj","subj":"T4006","obj":"T4004"},{"id":"R1001","pred":"prep","subj":"T4007","obj":"T4006"},{"id":"R1002","pred":"cc","subj":"T3838","obj":"T3837"},{"id":"R1003","pred":"pobj","subj":"T4008","obj":"T4007"},{"id":"R1004","pred":"punct","subj":"T4009","obj":"T3998"},{"id":"R1005","pred":"expl","subj":"T4010","obj":"T3998"},{"id":"R1006","pred":"amod","subj":"T3839","obj":"T3840"},{"id":"R1007","pred":"det","subj":"T4011","obj":"T4012"},{"id":"R1008","pred":"attr","subj":"T4012","obj":"T3998"},{"id":"R1009","pred":"prep","subj":"T4013","obj":"T4012"},{"id":"R1010","pred":"amod","subj":"T4014","obj":"T4015"},{"id":"R1011","pred":"conj","subj":"T3840","obj":"T3837"},{"id":"R1012","pred":"pobj","subj":"T4015","obj":"T4013"},{"id":"R1013","pred":"aux","subj":"T4016","obj":"T4017"},{"id":"R1014","pred":"punct","subj":"T3841","obj":"T3817"},{"id":"R1015","pred":"advcl","subj":"T4017","obj":"T4015"},{"id":"R1016","pred":"det","subj":"T4018","obj":"T4019"},{"id":"R1017","pred":"dobj","subj":"T4019","obj":"T4017"},{"id":"R1018","pred":"punct","subj":"T4020","obj":"T3998"},{"id":"R1019","pred":"prep","subj":"T3843","obj":"T3844"},{"id":"R1020","pred":"det","subj":"T4022","obj":"T4023"},{"id":"R1021","pred":"nsubj","subj":"T4023","obj":"T4024"},{"id":"R1022","pred":"prep","subj":"T4025","obj":"T4023"},{"id":"R1023","pred":"punct","subj":"T4057","obj":"T4058"},{"id":"R1024","pred":"pcomp","subj":"T4026","obj":"T4025"},{"id":"R1025","pred":"amod","subj":"T4027","obj":"T4028"},{"id":"R1026","pred":"dobj","subj":"T4028","obj":"T4026"},{"id":"R1027","pred":"prep","subj":"T4029","obj":"T4028"},{"id":"R1028","pred":"pobj","subj":"T4030","obj":"T4029"},{"id":"R1029","pred":"aux","subj":"T4031","obj":"T4024"},{"id":"R1030","pred":"parataxis","subj":"T4058","obj":"T4047"},{"id":"R1031","pred":"det","subj":"T4032","obj":"T4033"},{"id":"R1032","pred":"attr","subj":"T4033","obj":"T4024"},{"id":"R1033","pred":"prep","subj":"T4034","obj":"T4033"},{"id":"R1034","pred":"punct","subj":"T4059","obj":"T4060"},{"id":"R1035","pred":"det","subj":"T4035","obj":"T4036"},{"id":"R1036","pred":"pobj","subj":"T4036","obj":"T4034"},{"id":"R1037","pred":"amod","subj":"T4037","obj":"T4036"},{"id":"R1038","pred":"compound","subj":"T4038","obj":"T4036"},{"id":"R1039","pred":"prep","subj":"T4060","obj":"T4058"},{"id":"R1040","pred":"aux","subj":"T4039","obj":"T4040"},{"id":"R1041","pred":"advcl","subj":"T4040","obj":"T4036"},{"id":"R1042","pred":"amod","subj":"T4041","obj":"T4042"},{"id":"R1043","pred":"punct","subj":"T4061","obj":"T4058"},{"id":"R1044","pred":"dobj","subj":"T4042","obj":"T4040"},{"id":"R1045","pred":"amod","subj":"T4043","obj":"T4042"},{"id":"R1046","pred":"punct","subj":"T4044","obj":"T4024"},{"id":"R1047","pred":"punct","subj":"T4062","obj":"T4056"},{"id":"R1048","pred":"mark","subj":"T4046","obj":"T4047"},{"id":"R1049","pred":"advcl","subj":"T4047","obj":"T4056"},{"id":"R1050","pred":"det","subj":"T4063","obj":"T4064"},{"id":"R1051","pred":"det","subj":"T4048","obj":"T4049"},{"id":"R1052","pred":"nsubjpass","subj":"T4049","obj":"T4047"},{"id":"R1053","pred":"compound","subj":"T4050","obj":"T4051"},{"id":"R1054","pred":"nsubj","subj":"T4064","obj":"T4056"},{"id":"R1055","pred":"compound","subj":"T4051","obj":"T4049"},{"id":"R1056","pred":"prep","subj":"T4052","obj":"T4049"},{"id":"R1057","pred":"pobj","subj":"T4053","obj":"T4052"},{"id":"R1058","pred":"preconj","subj":"T4065","obj":"T4066"},{"id":"R1059","pred":"aux","subj":"T4054","obj":"T4047"},{"id":"R1060","pred":"auxpass","subj":"T4055","obj":"T4047"},{"id":"R1061","pred":"acomp","subj":"T4066","obj":"T4056"},{"id":"R1062","pred":"advmod","subj":"T4067","obj":"T4066"},{"id":"R1063","pred":"cc","subj":"T4068","obj":"T4066"},{"id":"R1064","pred":"conj","subj":"T4069","obj":"T4066"},{"id":"R1065","pred":"punct","subj":"T4162","obj":"T4156"},{"id":"R1066","pred":"aux","subj":"T4070","obj":"T4071"},{"id":"R1067","pred":"appos","subj":"T4163","obj":"T4156"},{"id":"R1068","pred":"punct","subj":"T4164","obj":"T4161"},{"id":"R1069","pred":"punct","subj":"T4165","obj":"T4154"},{"id":"R1070","pred":"neg","subj":"T4166","obj":"T4154"},{"id":"R1071","pred":"prep","subj":"T4167","obj":"T4154"},{"id":"R1072","pred":"xcomp","subj":"T4071","obj":"T4069"},{"id":"R1073","pred":"pobj","subj":"T4168","obj":"T4167"},{"id":"R1074","pred":"punct","subj":"T4169","obj":"T4168"},{"id":"R1075","pred":"amod","subj":"T4072","obj":"T4073"},{"id":"R1076","pred":"det","subj":"T4170","obj":"T4171"},{"id":"R1077","pred":"appos","subj":"T4171","obj":"T4168"},{"id":"R1078","pred":"amod","subj":"T4172","obj":"T4171"},{"id":"R1079","pred":"prep","subj":"T4173","obj":"T4171"},{"id":"R1080","pred":"dobj","subj":"T4073","obj":"T4071"},{"id":"R1081","pred":"pobj","subj":"T4174","obj":"T4173"},{"id":"R1082","pred":"punct","subj":"T4175","obj":"T4144"},{"id":"R1083","pred":"punct","subj":"T4074","obj":"T4056"},{"id":"R1084","pred":"mark","subj":"T4177","obj":"T4178"},{"id":"R1085","pred":"advcl","subj":"T4178","obj":"T4181"},{"id":"R1086","pred":"advmod","subj":"T4076","obj":"T4077"},{"id":"R1087","pred":"det","subj":"T4179","obj":"T4180"},{"id":"R1088","pred":"nsubj","subj":"T4180","obj":"T4178"},{"id":"R1089","pred":"neg","subj":"T4182","obj":"T4178"},{"id":"R1090","pred":"punct","subj":"T4078","obj":"T4077"},{"id":"R1091","pred":"prep","subj":"T4183","obj":"T4178"},{"id":"R1092","pred":"pobj","subj":"T4184","obj":"T4183"},{"id":"R1093","pred":"punct","subj":"T4185","obj":"T4181"},{"id":"R1094","pred":"det","subj":"T4186","obj":"T4187"},{"id":"R1095","pred":"nsubj","subj":"T4187","obj":"T4181"},{"id":"R1096","pred":"nsubj","subj":"T4079","obj":"T4077"},{"id":"R1097","pred":"prep","subj":"T4188","obj":"T4187"},{"id":"R1098","pred":"det","subj":"T4189","obj":"T4190"},{"id":"R1099","pred":"pobj","subj":"T4190","obj":"T4188"},{"id":"R1100","pred":"compound","subj":"T4191","obj":"T4190"},{"id":"R1101","pred":"prep","subj":"T4080","obj":"T4079"},{"id":"R1102","pred":"compound","subj":"T4192","obj":"T4190"},{"id":"R1103","pred":"prep","subj":"T4193","obj":"T4187"},{"id":"R1104","pred":"amod","subj":"T4194","obj":"T4195"},{"id":"R1105","pred":"det","subj":"T4081","obj":"T4082"},{"id":"R1106","pred":"pobj","subj":"T4195","obj":"T4193"},{"id":"R1107","pred":"amod","subj":"T4196","obj":"T4195"},{"id":"R1108","pred":"acomp","subj":"T4197","obj":"T4181"},{"id":"R1109","pred":"pobj","subj":"T4082","obj":"T4080"},{"id":"R1110","pred":"punct","subj":"T4198","obj":"T4181"},{"id":"R1111","pred":"det","subj":"T4200","obj":"T4201"},{"id":"R1112","pred":"compound","subj":"T4083","obj":"T4082"},{"id":"R1113","pred":"nsubj","subj":"T4201","obj":"T4202"},{"id":"R1114","pred":"prep","subj":"T4203","obj":"T4201"},{"id":"R1115","pred":"prep","subj":"T4084","obj":"T4082"},{"id":"R1116","pred":"det","subj":"T4204","obj":"T4205"},{"id":"R1117","pred":"pobj","subj":"T4205","obj":"T4203"},{"id":"R1118","pred":"amod","subj":"T4206","obj":"T4205"},{"id":"R1119","pred":"amod","subj":"T4085","obj":"T4086"},{"id":"R1120","pred":"aux","subj":"T4207","obj":"T4208"},{"id":"R1121","pred":"xcomp","subj":"T4208","obj":"T4202"},{"id":"R1122","pred":"advmod","subj":"T4209","obj":"T4210"},{"id":"R1123","pred":"amod","subj":"T4210","obj":"T4211"},{"id":"R1124","pred":"dobj","subj":"T4211","obj":"T4208"},{"id":"R1125","pred":"amod","subj":"T4212","obj":"T4211"},{"id":"R1126","pred":"pobj","subj":"T4086","obj":"T4084"},{"id":"R1127","pred":"prep","subj":"T4213","obj":"T4211"},{"id":"R1128","pred":"pobj","subj":"T4214","obj":"T4213"},{"id":"R1129","pred":"aux","subj":"T4087","obj":"T4077"},{"id":"R1130","pred":"dep","subj":"T4215","obj":"T4216"},{"id":"R1131","pred":"relcl","subj":"T4216","obj":"T4211"},{"id":"R1132","pred":"det","subj":"T4217","obj":"T4218"},{"id":"R1133","pred":"det","subj":"T4088","obj":"T4089"},{"id":"R1134","pred":"dobj","subj":"T4218","obj":"T4216"},{"id":"R1135","pred":"prep","subj":"T4219","obj":"T4218"},{"id":"R1136","pred":"det","subj":"T4220","obj":"T4221"},{"id":"R1137","pred":"pobj","subj":"T4221","obj":"T4219"},{"id":"R1138","pred":"dobj","subj":"T4089","obj":"T4077"},{"id":"R1139","pred":"amod","subj":"T4222","obj":"T4221"},{"id":"R1140","pred":"cc","subj":"T4223","obj":"T4222"},{"id":"R1141","pred":"conj","subj":"T4224","obj":"T4222"},{"id":"R1142","pred":"prep","subj":"T4090","obj":"T4089"},{"id":"R1143","pred":"amod","subj":"T4225","obj":"T4221"},{"id":"R1144","pred":"prep","subj":"T4226","obj":"T4221"},{"id":"R1145","pred":"det","subj":"T4091","obj":"T4092"},{"id":"R1146","pred":"det","subj":"T4227","obj":"T4228"},{"id":"R1147","pred":"pobj","subj":"T4228","obj":"T4226"},{"id":"R1148","pred":"amod","subj":"T4229","obj":"T4228"},{"id":"R1149","pred":"pobj","subj":"T4092","obj":"T4090"},{"id":"R1150","pred":"punct","subj":"T4230","obj":"T4202"},{"id":"R1151","pred":"det","subj":"T4232","obj":"T4233"},{"id":"R1152","pred":"prep","subj":"T4093","obj":"T4092"},{"id":"R1153","pred":"nsubjpass","subj":"T4233","obj":"T4235"},{"id":"R1154","pred":"amod","subj":"T4234","obj":"T4233"},{"id":"R1155","pred":"det","subj":"T4094","obj":"T4095"},{"id":"R1156","pred":"auxpass","subj":"T4236","obj":"T4235"},{"id":"R1157","pred":"prep","subj":"T4237","obj":"T4235"},{"id":"R1158","pred":"pobj","subj":"T4095","obj":"T4093"},{"id":"R1159","pred":"amod","subj":"T4238","obj":"T4239"},{"id":"R1160","pred":"pobj","subj":"T4239","obj":"T4237"},{"id":"R1161","pred":"prep","subj":"T4240","obj":"T4239"},{"id":"R1162","pred":"punct","subj":"T4096","obj":"T4097"},{"id":"R1163","pred":"parataxis","subj":"T4097","obj":"T4077"},{"id":"R1164","pred":"det","subj":"T4241","obj":"T4242"},{"id":"R1165","pred":"punct","subj":"T4098","obj":"T4097"},{"id":"R1166","pred":"pobj","subj":"T4242","obj":"T4240"},{"id":"R1167","pred":"compound","subj":"T4243","obj":"T4242"},{"id":"R1168","pred":"punct","subj":"T4099","obj":"T4077"},{"id":"R1169","pred":"prep","subj":"T4244","obj":"T4242"},{"id":"R1170","pred":"pobj","subj":"T4245","obj":"T4244"},{"id":"R1171","pred":"prep","subj":"T4246","obj":"T4239"},{"id":"R1172","pred":"advcl","subj":"T4100","obj":"T4077"},{"id":"R1173","pred":"amod","subj":"T4247","obj":"T4248"},{"id":"R1174","pred":"pobj","subj":"T4248","obj":"T4246"},{"id":"R1175","pred":"prep","subj":"T4249","obj":"T4239"},{"id":"R1176","pred":"nmod","subj":"T4250","obj":"T4251"},{"id":"R1177","pred":"nmod","subj":"T4251","obj":"T4254"},{"id":"R1178","pred":"det","subj":"T4101","obj":"T4102"},{"id":"R1179","pred":"nmod","subj":"T4252","obj":"T4251"},{"id":"R1180","pred":"punct","subj":"T4253","obj":"T4251"},{"id":"R1181","pred":"nsubj","subj":"T4102","obj":"T4103"},{"id":"R1182","pred":"pobj","subj":"T4254","obj":"T4249"},{"id":"R1183","pred":"punct","subj":"T4255","obj":"T4254"},{"id":"R1184","pred":"punct","subj":"T4256","obj":"T4235"},{"id":"R1185","pred":"ccomp","subj":"T4103","obj":"T4100"},{"id":"R1186","pred":"det","subj":"T4258","obj":"T4259"},{"id":"R1187","pred":"nsubjpass","subj":"T4259","obj":"T4260"},{"id":"R1188","pred":"det","subj":"T4104","obj":"T4103"},{"id":"R1189","pred":"prep","subj":"T4261","obj":"T4259"},{"id":"R1190","pred":"amod","subj":"T4262","obj":"T4263"},{"id":"R1191","pred":"advmod","subj":"T4105","obj":"T4106"},{"id":"R1192","pred":"pobj","subj":"T4263","obj":"T4261"},{"id":"R1193","pred":"auxpass","subj":"T4264","obj":"T4260"},{"id":"R1194","pred":"prep","subj":"T4265","obj":"T4260"},{"id":"R1195","pred":"amod","subj":"T4106","obj":"T4103"},{"id":"R1196","pred":"amod","subj":"T4266","obj":"T4267"},{"id":"R1197","pred":"pobj","subj":"T4267","obj":"T4265"},{"id":"R1198","pred":"prep","subj":"T4107","obj":"T4103"},{"id":"R1199","pred":"det","subj":"T4108","obj":"T4109"},{"id":"R1200","pred":"amod","subj":"T4268","obj":"T4267"},{"id":"R1201","pred":"prep","subj":"T4269","obj":"T4267"},{"id":"R1202","pred":"pobj","subj":"T4109","obj":"T4107"},{"id":"R1203","pred":"det","subj":"T4270","obj":"T4271"},{"id":"R1204","pred":"pobj","subj":"T4271","obj":"T4269"},{"id":"R1205","pred":"amod","subj":"T4110","obj":"T4109"},{"id":"R1206","pred":"compound","subj":"T4272","obj":"T4271"},{"id":"R1207","pred":"compound","subj":"T4273","obj":"T4271"},{"id":"R1208","pred":"punct","subj":"T4274","obj":"T4260"},{"id":"R1209","pred":"punct","subj":"T4111","obj":"T4077"},{"id":"R1210","pred":"det","subj":"T4276","obj":"T4277"},{"id":"R1211","pred":"nsubj","subj":"T4277","obj":"T4278"},{"id":"R1212","pred":"advmod","subj":"T4113","obj":"T4114"},{"id":"R1213","pred":"det","subj":"T4279","obj":"T4280"},{"id":"R1214","pred":"dobj","subj":"T4280","obj":"T4278"},{"id":"R1215","pred":"cc","subj":"T4281","obj":"T4280"},{"id":"R1216","pred":"conj","subj":"T4282","obj":"T4280"},{"id":"R1217","pred":"punct","subj":"T4115","obj":"T4114"},{"id":"R1218","pred":"prep","subj":"T4283","obj":"T4280"},{"id":"R1219","pred":"det","subj":"T4284","obj":"T4285"},{"id":"R1220","pred":"pobj","subj":"T4285","obj":"T4283"},{"id":"R1221","pred":"amod","subj":"T4286","obj":"T4285"},{"id":"R1222","pred":"det","subj":"T4116","obj":"T4117"},{"id":"R1223","pred":"prep","subj":"T4287","obj":"T4285"},{"id":"R1224","pred":"pobj","subj":"T4288","obj":"T4287"},{"id":"R1225","pred":"punct","subj":"T4289","obj":"T4278"},{"id":"R1226","pred":"det","subj":"T4291","obj":"T4292"},{"id":"R1227","pred":"npadvmod","subj":"T4117","obj":"T4124"},{"id":"R1228","pred":"nsubj","subj":"T4292","obj":"T4293"},{"id":"R1229","pred":"aux","subj":"T4294","obj":"T4293"},{"id":"R1230","pred":"prep","subj":"T4295","obj":"T4293"},{"id":"R1231","pred":"compound","subj":"T4118","obj":"T4119"},{"id":"R1232","pred":"det","subj":"T4296","obj":"T4297"},{"id":"R1233","pred":"pobj","subj":"T4297","obj":"T4295"},{"id":"R1234","pred":"prep","subj":"T4298","obj":"T4297"},{"id":"R1235","pred":"compound","subj":"T4119","obj":"T4117"},{"id":"R1236","pred":"amod","subj":"T4299","obj":"T4300"},{"id":"R1237","pred":"pobj","subj":"T4300","obj":"T4298"},{"id":"R1238","pred":"compound","subj":"T4301","obj":"T4300"},{"id":"R1239","pred":"punct","subj":"T4120","obj":"T4119"},{"id":"R1240","pred":"punct","subj":"T4302","obj":"T4300"},{"id":"R1241","pred":"amod","subj":"T4303","obj":"T4304"},{"id":"R1242","pred":"prep","subj":"T4304","obj":"T4300"},{"id":"R1243","pred":"punct","subj":"T4121","obj":"T4117"},{"id":"R1244","pred":"nmod","subj":"T4305","obj":"T4306"},{"id":"R1245","pred":"pobj","subj":"T4306","obj":"T4304"},{"id":"R1246","pred":"cc","subj":"T4307","obj":"T4305"},{"id":"R1247","pred":"compound","subj":"T4122","obj":"T4117"},{"id":"R1248","pred":"compound","subj":"T4308","obj":"T4309"},{"id":"R1249","pred":"conj","subj":"T4309","obj":"T4305"},{"id":"R1250","pred":"punct","subj":"T4310","obj":"T4293"},{"id":"R1251","pred":"aux","subj":"T4311","obj":"T4312"},{"id":"R1252","pred":"punct","subj":"T4123","obj":"T4117"},{"id":"R1253","pred":"advcl","subj":"T4312","obj":"T4293"},{"id":"R1254","pred":"advmod","subj":"T4313","obj":"T4312"},{"id":"R1255","pred":"dobj","subj":"T4314","obj":"T4312"},{"id":"R1256","pred":"amod","subj":"T4124","obj":"T4129"},{"id":"R1257","pred":"punct","subj":"T4315","obj":"T4293"},{"id":"R1258","pred":"punct","subj":"T4125","obj":"T4117"},{"id":"R1259","pred":"appos","subj":"T4126","obj":"T4117"},{"id":"R1260","pred":"punct","subj":"T4127","obj":"T4124"},{"id":"R1261","pred":"punct","subj":"T4128","obj":"T4124"},{"id":"R1262","pred":"nsubjpass","subj":"T4129","obj":"T4114"},{"id":"R1263","pred":"compound","subj":"T4130","obj":"T4129"},{"id":"R1264","pred":"dep","subj":"T4131","obj":"T4132"},{"id":"R1265","pred":"relcl","subj":"T4132","obj":"T4129"},{"id":"R1266","pred":"advmod","subj":"T4133","obj":"T4132"},{"id":"R1267","pred":"amod","subj":"T4134","obj":"T4135"},{"id":"R1268","pred":"dobj","subj":"T4135","obj":"T4132"},{"id":"R1269","pred":"aux","subj":"T4136","obj":"T4114"},{"id":"R1270","pred":"auxpass","subj":"T4137","obj":"T4114"},{"id":"R1271","pred":"punct","subj":"T4138","obj":"T4139"},{"id":"R1272","pred":"parataxis","subj":"T4139","obj":"T4114"},{"id":"R1273","pred":"punct","subj":"T4140","obj":"T4139"},{"id":"R1274","pred":"punct","subj":"T4141","obj":"T4114"},{"id":"R1275","pred":"advmod","subj":"T4143","obj":"T4144"},{"id":"R1276","pred":"punct","subj":"T4145","obj":"T4144"},{"id":"R1277","pred":"det","subj":"T4146","obj":"T4147"},{"id":"R1278","pred":"nsubj","subj":"T4147","obj":"T4144"},{"id":"R1279","pred":"prep","subj":"T4148","obj":"T4147"},{"id":"R1280","pred":"det","subj":"T4149","obj":"T4150"},{"id":"R1281","pred":"pobj","subj":"T4150","obj":"T4148"},{"id":"R1282","pred":"det","subj":"T4151","obj":"T4152"},{"id":"R1283","pred":"dobj","subj":"T4152","obj":"T4144"},{"id":"R1284","pred":"compound","subj":"T4153","obj":"T4152"},{"id":"R1285","pred":"prep","subj":"T4154","obj":"T4152"},{"id":"R1286","pred":"det","subj":"T4155","obj":"T4156"},{"id":"R1287","pred":"nmod","subj":"T4156","obj":"T4161"},{"id":"R1288","pred":"amod","subj":"T4157","obj":"T4156"},{"id":"R1289","pred":"amod","subj":"T4158","obj":"T4159"},{"id":"R1290","pred":"nmod","subj":"T4159","obj":"T4156"},{"id":"R1291","pred":"punct","subj":"T4160","obj":"T4159"},{"id":"R1292","pred":"pobj","subj":"T4161","obj":"T4154"},{"id":"R643","pred":"det","subj":"T3628","obj":"T3629"},{"id":"R987","pred":"punct","subj":"T3995","obj":"T3970"},{"id":"R988","pred":"prep","subj":"T3997","obj":"T3998"},{"id":"R993","pred":"pobj","subj":"T4001","obj":"T3997"}],"text":"Background\nMaple Syrup Urine Disease (MSUD) is a genetic disorder caused by a deficiency of branched-chain keto acid dehydrogenase (BCKDH), a mitochondrial multienzyme complex responsible for the oxidative decarboxylation of branched-chain keto acids derived from branched-chain amino acids (BCAA), leucine, isoleucine and valine (for review, see: [1]).\nPatients with MSUD, depending on the mutation, show variable degrees of enzyme deficiency leading to several different clinical phenotypes [1]. Approximately 75% of MSUD patients have the classic form of the disease with BCKDH activity in the range of 0–2% of normal [1]. These patients show markedly elevated levels of BCAA in blood and other body fluids [1]. Besides the classic form, there are other variants of the disease. Patients with the intermediate form of the disease show BCKDH activity in the range of 3–30% of normal. In such patients the onset of the disease is delayed, but there are persistently elevated levels of BCAA [1]. Patients with the intermittent form of MSUD show BCKDH activity in the range of 5–20% and during the asymptomatic phase the blood BCAA levels are normal [1]. The overall incidence of MSUD in the general population is 1:185,000 [1], and in certain population groups, such as Mennonites of Pennsylvania, the incidence is estimated to be as high as 1:176 [2].\nThe BCKDH complex, the deficient enzyme in MSUD, consists of three catalytic proteins, a decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoyl dehydrogenase (E3). The E1 component is a heterotetramer composed of two α and two β subunits [3]. The E1 and E2 components are specific to BCKDH, whereas E3 is also used by pyruvate and α-ketoglutarate dehydrogenase complexes [3] and the glycine cleavage system [4]. BCKDH is also associated with two regulatory proteins, a specific kinase and a phosphatase which regulate the activity of this enzyme through a phosphorylation (inactivation) and dephosphorylation (activation) cycle of the E1 α subunit [5,6]. Mutations in the genes of the E1 and E2 subunits of BCKDH have been described, however, the majority of MSUD mutations identified thus far are in the E2 subunit [1,7]. To date, cases of MSUD have not been associated with defects in the regulatory kinase and phosphatase [1].\nCurrent management of MSUD patients relies on a strict lifelong dietary restriction of protein or BCAA [1,8]. Such a dietary management of the disease, however, is not entirely satisfactory especially in times of metabolic decompensation due to infection, injuries and other stressors. In spite of dietary intervention, there is significant mortality associated with MSUD and there is a high incidence of mental retardation in survivors [9].\nBecause of the central role of the liver in amino acid metabolism and moderate/high levels of BCKDH activity in human liver [10-12], a few cases of MSUD have recently been treated by liver transplantation [13-16]. While the short-term outcome of liver transplantation is encouraging, long-term effects of this approach are not known. However, these patients are now required to take immunosuppressant drugs for the rest of their lives, often with undesirable side effects. Moreover, the cost associated with liver transplantation and the availability of donor livers are additional limiting factors for the practicality of treatment of this disease.\nBecause of the current unsatisfactory options for the treatment of MSUD, there is a need for improved therapies to combat this disease. An obstacle to developing novel treatments for MSUD has been the lack of a suitable animal model to perform necessary preclinical studies. Although a Hereford calf model with MSUD has been described [17-19], this model is neither readily available nor practical to perform preclinical studies. Furthermore, comparison of this animal model with human MSUD has shown some differences in the pathology of the disease [1], making this animal a less desirable model for the human disease.\nRecently, a N-ethyl-N-nitrosourea (ENU)-induced mutant mouse that phenotypically resembles human MSUD has been described [20]. However, the mutation in this model disrupts a splice site in the mitochondrial branched-chain aminotransferase (BCAT) gene, not in BCKDH, the deficient enzyme in MSUD. Because the mutation is not in BCKDH, the validity of this mutant mouse line for modeling human MSUD is questionable.\nThe objective of the present study was to create genetically engineered murine models of MSUD that mimic the pathology of the classic and intermediate variant forms of the human disease. The classic model was created by targeted inactivation of the E2 subunit of BCKDH by homologous recombination in embryonic stem (ES) cells. The model of intermediate MSUD was created by partial transgenic rescue of the E2 gene knockout. This report describes the generation and characterization of these murine models of MSUD. These models will allow for the development of novel treatment approaches, such as gene or stem cell therapies, to ultimately cure MSUD."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T3189","span":{"begin":240,"end":250},"obj":"CHEBI:25754"},{"id":"T3190","span":{"begin":264,"end":290},"obj":"CHEBI:22918"},{"id":"T3191","span":{"begin":279,"end":290},"obj":"CHEBI_SO_EXT:amino_acid"},{"id":"T3192","span":{"begin":292,"end":296},"obj":"CHEBI:22918"},{"id":"T3193","span":{"begin":299,"end":306},"obj":"CHEBI_SO_EXT:leucine"},{"id":"T3194","span":{"begin":308,"end":318},"obj":"CHEBI_SO_EXT:isoleucine"},{"id":"T3195","span":{"begin":323,"end":329},"obj":"CHEBI_SO_EXT:valine"},{"id":"T3196","span":{"begin":391,"end":399},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T3197","span":{"begin":426,"end":432},"obj":"CHEBI_GO_SO_EXT:enzyme"},{"id":"T3198","span":{"begin":674,"end":678},"obj":"CHEBI:22918"},{"id":"T3199","span":{"begin":682,"end":687},"obj":"UBERON:0000178"},{"id":"T3200","span":{"begin":698,"end":709},"obj":"UBERON:0006314"},{"id":"T3201","span":{"begin":986,"end":990},"obj":"CHEBI:22918"},{"id":"T3202","span":{"begin":1120,"end":1125},"obj":"UBERON:0000178"},{"id":"T3203","span":{"begin":1126,"end":1130},"obj":"CHEBI:22918"},{"id":"T3204","span":{"begin":1357,"end":1370},"obj":"GO:0017086"},{"id":"T3205","span":{"begin":1386,"end":1392},"obj":"CHEBI_GO_SO_EXT:enzyme"},{"id":"T3206","span":{"begin":1420,"end":1429},"obj":"GO_MOP_EXT:catalysis"},{"id":"T3207","span":{"begin":1430,"end":1438},"obj":"CHEBI_PR_EXT:protein"},{"id":"T3208","span":{"begin":1442,"end":1455},"obj":"GO_EXT:0016831"},{"id":"T3209","span":{"begin":1464,"end":1477},"obj":"CHEBI:50488"},{"id":"T3210","span":{"begin":1464,"end":1490},"obj":"GO_PR_EXT:dihydrolipoyllysine_residue_2_methylpropanoyl_transferase"},{"id":"T3211","span":{"begin":1492,"end":1494},"obj":"PR_EXT:000006300"},{"id":"T3212","span":{"begin":1503,"end":1516},"obj":"CHEBI:50488"},{"id":"T3213","span":{"begin":1503,"end":1530},"obj":"GO_PR_EXT:dihydrolipoamide_dehydrogenase"},{"id":"T3214","span":{"begin":1532,"end":1534},"obj":"PR_EXT:000006506"},{"id":"T3215","span":{"begin":1565,"end":1573},"obj":"GO_EXT:tetrameric_macromolecular_complex"},{"id":"T3216","span":{"begin":1590,"end":1591},"obj":"_FRAGMENT"},{"id":"T3217","span":{"begin":1602,"end":1610},"obj":"PR_EXT:000004686"},{"id":"T3218","span":{"begin":1600,"end":1610},"obj":"PR_EXT:000004687"},{"id":"T3219","span":{"begin":1627,"end":1629},"obj":"PR_EXT:000006300"},{"id":"T3220","span":{"begin":1672,"end":1674},"obj":"PR_EXT:000006506"},{"id":"T3221","span":{"begin":1691,"end":1699},"obj":"CHEBI:15361"},{"id":"T3222","span":{"begin":1691,"end":1699},"obj":"_FRAGMENT"},{"id":"T3223","span":{"begin":1720,"end":1733},"obj":"GO_EXT:0004738"},{"id":"T3224","span":{"begin":1720,"end":1743},"obj":"GO:0045254"},{"id":"T3225","span":{"begin":1704,"end":1719},"obj":"CHEBI_EXT:2_oxoglutarate"},{"id":"T3226","span":{"begin":1704,"end":1733},"obj":"GO_EXT:0004591"},{"id":"T3227","span":{"begin":1704,"end":1743},"obj":"GO:0045240"},{"id":"T3228","span":{"begin":1756,"end":1763},"obj":"CHEBI_SO_EXT:glycine"},{"id":"T3229","span":{"begin":1756,"end":1779},"obj":"GO:0005960"},{"id":"T3230","span":{"begin":1764,"end":1772},"obj":"MOP:0000780"},{"id":"T3231","span":{"begin":1819,"end":1829},"obj":"GO:0065007"},{"id":"T3232","span":{"begin":1830,"end":1838},"obj":"CHEBI_PR_EXT:protein"},{"id":"T3233","span":{"begin":1851,"end":1857},"obj":"GO_EXT:0016301"},{"id":"T3234","span":{"begin":1864,"end":1875},"obj":"GO_EXT:0016791"},{"id":"T3235","span":{"begin":1882,"end":1890},"obj":"GO:0065007"},{"id":"T3236","span":{"begin":1912,"end":1918},"obj":"CHEBI_GO_SO_EXT:enzyme"},{"id":"T3237","span":{"begin":1929,"end":1944},"obj":"GO_PATO_EXT:phosphorylation_process"},{"id":"T3238","span":{"begin":1964,"end":1981},"obj":"GO:0016311"},{"id":"T3239","span":{"begin":2008,"end":2020},"obj":"PR_EXT:000004686"},{"id":"T3240","span":{"begin":2028,"end":2037},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T3241","span":{"begin":2045,"end":2050},"obj":"SO_EXT:0000704"},{"id":"T3242","span":{"begin":2065,"end":2085},"obj":"PR_EXT:000006300"},{"id":"T3243","span":{"begin":2137,"end":2146},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T3244","span":{"begin":2178,"end":2188},"obj":"PR_EXT:000006300"},{"id":"T3245","span":{"begin":2264,"end":2274},"obj":"GO:0065007"},{"id":"T3246","span":{"begin":2275,"end":2281},"obj":"GO_EXT:0016301"},{"id":"T3247","span":{"begin":2286,"end":2297},"obj":"GO_EXT:0016791"},{"id":"T3248","span":{"begin":2390,"end":2397},"obj":"CHEBI_PR_EXT:protein"},{"id":"T3249","span":{"begin":2401,"end":2405},"obj":"CHEBI:22918"},{"id":"T3250","span":{"begin":2516,"end":2525},"obj":"GO:0008152"},{"id":"T3251","span":{"begin":2780,"end":2785},"obj":"UBERON:0002107"},{"id":"T3252","span":{"begin":2789,"end":2799},"obj":"CHEBI_SO_EXT:amino_acid"},{"id":"T3253","span":{"begin":2789,"end":2810},"obj":"GO:0006520"},{"id":"T3254","span":{"begin":2857,"end":2862},"obj":"NCBITaxon:9606"},{"id":"T3255","span":{"begin":2863,"end":2868},"obj":"UBERON:0002107"},{"id":"T3256","span":{"begin":2928,"end":2933},"obj":"UBERON:0002107"},{"id":"T3257","span":{"begin":2991,"end":2996},"obj":"UBERON:0002107"},{"id":"T3258","span":{"begin":3128,"end":3145},"obj":"CHEBI_EXT:35705"},{"id":"T3259","span":{"begin":3146,"end":3151},"obj":"CHEBI_EXT:23888"},{"id":"T3260","span":{"begin":3253,"end":3258},"obj":"UBERON:0002107"},{"id":"T3261","span":{"begin":3305,"end":3311},"obj":"UBERON:0002107"},{"id":"T3262","span":{"begin":3615,"end":3621},"obj":"NCBITaxon:33208"},{"id":"T3263","span":{"begin":3690,"end":3694},"obj":"NCBITaxon_UBERON_EXT:calf"},{"id":"T3264","span":{"begin":3857,"end":3863},"obj":"NCBITaxon:33208"},{"id":"T3265","span":{"begin":3875,"end":3880},"obj":"NCBITaxon:9606"},{"id":"T3266","span":{"begin":3962,"end":3968},"obj":"NCBITaxon:33208"},{"id":"T3267","span":{"begin":4000,"end":4005},"obj":"NCBITaxon:9606"},{"id":"T3268","span":{"begin":4027,"end":4048},"obj":"CHEBI:23995"},{"id":"T3269","span":{"begin":4050,"end":4053},"obj":"CHEBI:23995"},{"id":"T3270","span":{"begin":4063,"end":4069},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T3271","span":{"begin":4070,"end":4075},"obj":"NCBITaxon:10088"},{"id":"T3272","span":{"begin":4106,"end":4111},"obj":"NCBITaxon:9606"},{"id":"T3273","span":{"begin":4155,"end":4163},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T3274","span":{"begin":4189,"end":4195},"obj":"GO:0008380"},{"id":"T3275","span":{"begin":4189,"end":4200},"obj":"SO_EXT:0000162"},{"id":"T3276","span":{"begin":4208,"end":4221},"obj":"GO:0005739"},{"id":"T3277","span":{"begin":4208,"end":4253},"obj":"PR_EXT:000004683"},{"id":"T3278","span":{"begin":4222,"end":4253},"obj":"GO_PR_EXT:branched_chain_amino_acid_aminotransferase"},{"id":"T3279","span":{"begin":4255,"end":4259},"obj":"GO_PR_EXT:branched_chain_amino_acid_aminotransferase"},{"id":"T3280","span":{"begin":4261,"end":4265},"obj":"SO_EXT:0000704"},{"id":"T3281","span":{"begin":4295,"end":4301},"obj":"CHEBI_GO_SO_EXT:enzyme"},{"id":"T3282","span":{"begin":4323,"end":4331},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T3283","span":{"begin":4370,"end":4376},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T3284","span":{"begin":4377,"end":4382},"obj":"NCBITaxon:10088"},{"id":"T3285","span":{"begin":4401,"end":4406},"obj":"NCBITaxon:9606"},{"id":"T3286","span":{"begin":4478,"end":4489},"obj":"SO_EXT:0000704"},{"id":"T3287","span":{"begin":4501,"end":4507},"obj":"NCBITaxon:39107"},{"id":"T3288","span":{"begin":4601,"end":4606},"obj":"NCBITaxon:9606"},{"id":"T3289","span":{"begin":4678,"end":4697},"obj":"PR_EXT:000006300"},{"id":"T3290","span":{"begin":4712,"end":4725},"obj":"GO_SO_EXT:sequence_rearrangement_process"},{"id":"T3181","span":{"begin":11,"end":16},"obj":"NCBITaxon:4022"},{"id":"T3182","span":{"begin":23,"end":28},"obj":"UBERON:0001088"},{"id":"T3183","span":{"begin":49,"end":56},"obj":"SO_EXT:0000704"},{"id":"T3184","span":{"begin":107,"end":116},"obj":"CHEBI:25754"},{"id":"T3185","span":{"begin":142,"end":155},"obj":"GO:0005739"},{"id":"T3186","span":{"begin":161,"end":167},"obj":"CHEBI_GO_SO_EXT:enzyme"},{"id":"T3187","span":{"begin":168,"end":175},"obj":"GO:0032991"},{"id":"T3188","span":{"begin":196,"end":205},"obj":"MOP:0000568"},{"id":"T3291","span":{"begin":4729,"end":4738},"obj":"UBERON:0000922"},{"id":"T3292","span":{"begin":4729,"end":4743},"obj":"_FRAGMENT"},{"id":"T3293","span":{"begin":4749,"end":4754},"obj":"CL:0002322"},{"id":"T3294","span":{"begin":4745,"end":4747},"obj":"_FRAGMENT"},{"id":"T3295","span":{"begin":4749,"end":4754},"obj":"CL_GO_EXT:cell"},{"id":"T3296","span":{"begin":4810,"end":4820},"obj":"SO_EXT:transgenic_entity"},{"id":"T3297","span":{"begin":4821,"end":4827},"obj":"SO_EXT:sequence_rescue_process"},{"id":"T3298","span":{"begin":4835,"end":4837},"obj":"PR_EXT:000006300"},{"id":"T3299","span":{"begin":4838,"end":4842},"obj":"SO_EXT:0000704"},{"id":"T3300","span":{"begin":4920,"end":4926},"obj":"NCBITaxon:39107"},{"id":"T3301","span":{"begin":5026,"end":5030},"obj":"SO_EXT:0000704"},{"id":"T3302","span":{"begin":5034,"end":5043},"obj":"CL:0000034"},{"id":"T3303","span":{"begin":5039,"end":5043},"obj":"CL_GO_EXT:cell"}],"relations":[{"id":"R343","pred":"_lexicallyChainedTo","subj":"T3217","obj":"T3216"},{"id":"R344","pred":"_lexicallyChainedTo","subj":"T3223","obj":"T3222"},{"id":"R345","pred":"_lexicallyChainedTo","subj":"T3224","obj":"T3222"},{"id":"R346","pred":"_lexicallyChainedTo","subj":"T3293","obj":"T3292"},{"id":"R347","pred":"_lexicallyChainedTo","subj":"T3293","obj":"T3294"}],"text":"Background\nMaple Syrup Urine Disease (MSUD) is a genetic disorder caused by a deficiency of branched-chain keto acid dehydrogenase (BCKDH), a mitochondrial multienzyme complex responsible for the oxidative decarboxylation of branched-chain keto acids derived from branched-chain amino acids (BCAA), leucine, isoleucine and valine (for review, see: [1]).\nPatients with MSUD, depending on the mutation, show variable degrees of enzyme deficiency leading to several different clinical phenotypes [1]. Approximately 75% of MSUD patients have the classic form of the disease with BCKDH activity in the range of 0–2% of normal [1]. These patients show markedly elevated levels of BCAA in blood and other body fluids [1]. Besides the classic form, there are other variants of the disease. Patients with the intermediate form of the disease show BCKDH activity in the range of 3–30% of normal. In such patients the onset of the disease is delayed, but there are persistently elevated levels of BCAA [1]. Patients with the intermittent form of MSUD show BCKDH activity in the range of 5–20% and during the asymptomatic phase the blood BCAA levels are normal [1]. The overall incidence of MSUD in the general population is 1:185,000 [1], and in certain population groups, such as Mennonites of Pennsylvania, the incidence is estimated to be as high as 1:176 [2].\nThe BCKDH complex, the deficient enzyme in MSUD, consists of three catalytic proteins, a decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoyl dehydrogenase (E3). The E1 component is a heterotetramer composed of two α and two β subunits [3]. The E1 and E2 components are specific to BCKDH, whereas E3 is also used by pyruvate and α-ketoglutarate dehydrogenase complexes [3] and the glycine cleavage system [4]. BCKDH is also associated with two regulatory proteins, a specific kinase and a phosphatase which regulate the activity of this enzyme through a phosphorylation (inactivation) and dephosphorylation (activation) cycle of the E1 α subunit [5,6]. Mutations in the genes of the E1 and E2 subunits of BCKDH have been described, however, the majority of MSUD mutations identified thus far are in the E2 subunit [1,7]. To date, cases of MSUD have not been associated with defects in the regulatory kinase and phosphatase [1].\nCurrent management of MSUD patients relies on a strict lifelong dietary restriction of protein or BCAA [1,8]. Such a dietary management of the disease, however, is not entirely satisfactory especially in times of metabolic decompensation due to infection, injuries and other stressors. In spite of dietary intervention, there is significant mortality associated with MSUD and there is a high incidence of mental retardation in survivors [9].\nBecause of the central role of the liver in amino acid metabolism and moderate/high levels of BCKDH activity in human liver [10-12], a few cases of MSUD have recently been treated by liver transplantation [13-16]. While the short-term outcome of liver transplantation is encouraging, long-term effects of this approach are not known. However, these patients are now required to take immunosuppressant drugs for the rest of their lives, often with undesirable side effects. Moreover, the cost associated with liver transplantation and the availability of donor livers are additional limiting factors for the practicality of treatment of this disease.\nBecause of the current unsatisfactory options for the treatment of MSUD, there is a need for improved therapies to combat this disease. An obstacle to developing novel treatments for MSUD has been the lack of a suitable animal model to perform necessary preclinical studies. Although a Hereford calf model with MSUD has been described [17-19], this model is neither readily available nor practical to perform preclinical studies. Furthermore, comparison of this animal model with human MSUD has shown some differences in the pathology of the disease [1], making this animal a less desirable model for the human disease.\nRecently, a N-ethyl-N-nitrosourea (ENU)-induced mutant mouse that phenotypically resembles human MSUD has been described [20]. However, the mutation in this model disrupts a splice site in the mitochondrial branched-chain aminotransferase (BCAT) gene, not in BCKDH, the deficient enzyme in MSUD. Because the mutation is not in BCKDH, the validity of this mutant mouse line for modeling human MSUD is questionable.\nThe objective of the present study was to create genetically engineered murine models of MSUD that mimic the pathology of the classic and intermediate variant forms of the human disease. The classic model was created by targeted inactivation of the E2 subunit of BCKDH by homologous recombination in embryonic stem (ES) cells. The model of intermediate MSUD was created by partial transgenic rescue of the E2 gene knockout. This report describes the generation and characterization of these murine models of MSUD. These models will allow for the development of novel treatment approaches, such as gene or stem cell therapies, to ultimately cure MSUD."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T3120","span":{"begin":1532,"end":1534},"obj":"PR:000006506"},{"id":"T3123","span":{"begin":1600,"end":1610},"obj":"PR:000004687"},{"id":"T3124","span":{"begin":1627,"end":1629},"obj":"PR:000006300"},{"id":"T3125","span":{"begin":1672,"end":1674},"obj":"PR:000006506"},{"id":"T3126","span":{"begin":1691,"end":1699},"obj":"CHEBI:15361"},{"id":"T3127","span":{"begin":1691,"end":1699},"obj":"_FRAGMENT"},{"id":"T3128","span":{"begin":1720,"end":1743},"obj":"GO:0045254"},{"id":"T3129","span":{"begin":1704,"end":1743},"obj":"GO:0045240"},{"id":"T3130","span":{"begin":1756,"end":1779},"obj":"GO:0005960"},{"id":"T3131","span":{"begin":1764,"end":1772},"obj":"MOP:0000780"},{"id":"T3132","span":{"begin":1819,"end":1829},"obj":"GO:0065007"},{"id":"T3133","span":{"begin":1882,"end":1890},"obj":"GO:0065007"},{"id":"T3134","span":{"begin":1964,"end":1981},"obj":"GO:0016311"},{"id":"T3135","span":{"begin":2008,"end":2020},"obj":"PR:000004686"},{"id":"T3136","span":{"begin":2045,"end":2050},"obj":"SO:0000704"},{"id":"T3137","span":{"begin":2065,"end":2085},"obj":"PR:000006300"},{"id":"T3138","span":{"begin":2178,"end":2188},"obj":"PR:000006300"},{"id":"T3139","span":{"begin":2264,"end":2274},"obj":"GO:0065007"},{"id":"T3140","span":{"begin":2401,"end":2405},"obj":"CHEBI:22918"},{"id":"T3141","span":{"begin":2516,"end":2525},"obj":"GO:0008152"},{"id":"T3142","span":{"begin":2780,"end":2785},"obj":"UBERON:0002107"},{"id":"T3143","span":{"begin":2789,"end":2810},"obj":"GO:0006520"},{"id":"T3144","span":{"begin":2857,"end":2862},"obj":"NCBITaxon:9606"},{"id":"T3145","span":{"begin":2863,"end":2868},"obj":"UBERON:0002107"},{"id":"T3146","span":{"begin":2928,"end":2933},"obj":"UBERON:0002107"},{"id":"T3147","span":{"begin":2991,"end":2996},"obj":"UBERON:0002107"},{"id":"T3148","span":{"begin":3128,"end":3145},"obj":"CHEBI:35705"},{"id":"T3149","span":{"begin":3146,"end":3151},"obj":"CHEBI:23888"},{"id":"T3150","span":{"begin":3253,"end":3258},"obj":"UBERON:0002107"},{"id":"T3151","span":{"begin":3305,"end":3311},"obj":"UBERON:0002107"},{"id":"T3152","span":{"begin":3615,"end":3621},"obj":"NCBITaxon:33208"},{"id":"T3153","span":{"begin":3857,"end":3863},"obj":"NCBITaxon:33208"},{"id":"T3154","span":{"begin":3875,"end":3880},"obj":"NCBITaxon:9606"},{"id":"T3155","span":{"begin":3962,"end":3968},"obj":"NCBITaxon:33208"},{"id":"T3156","span":{"begin":4000,"end":4005},"obj":"NCBITaxon:9606"},{"id":"T3157","span":{"begin":4027,"end":4048},"obj":"CHEBI:23995"},{"id":"T3158","span":{"begin":4050,"end":4053},"obj":"CHEBI:23995"},{"id":"T3159","span":{"begin":4070,"end":4075},"obj":"NCBITaxon:10088"},{"id":"T3160","span":{"begin":4106,"end":4111},"obj":"NCBITaxon:9606"},{"id":"T3161","span":{"begin":4189,"end":4195},"obj":"GO:0008380"},{"id":"T3162","span":{"begin":4189,"end":4200},"obj":"SO:0000162"},{"id":"T3163","span":{"begin":4208,"end":4221},"obj":"GO:0005739"},{"id":"T3164","span":{"begin":4208,"end":4253},"obj":"PR:000004683"},{"id":"T3165","span":{"begin":4261,"end":4265},"obj":"SO:0000704"},{"id":"T3166","span":{"begin":4377,"end":4382},"obj":"NCBITaxon:10088"},{"id":"T3167","span":{"begin":4401,"end":4406},"obj":"NCBITaxon:9606"},{"id":"T3168","span":{"begin":4478,"end":4489},"obj":"SO:0000704"},{"id":"T3169","span":{"begin":4501,"end":4507},"obj":"NCBITaxon:39107"},{"id":"T3170","span":{"begin":4601,"end":4606},"obj":"NCBITaxon:9606"},{"id":"T3171","span":{"begin":4678,"end":4697},"obj":"PR:000006300"},{"id":"T3172","span":{"begin":4729,"end":4738},"obj":"UBERON:0000922"},{"id":"T3173","span":{"begin":4729,"end":4743},"obj":"_FRAGMENT"},{"id":"T3174","span":{"begin":4749,"end":4754},"obj":"CL:0002322"},{"id":"T3175","span":{"begin":4745,"end":4747},"obj":"_FRAGMENT"},{"id":"T3176","span":{"begin":4835,"end":4837},"obj":"PR:000006300"},{"id":"T3177","span":{"begin":4838,"end":4842},"obj":"SO:0000704"},{"id":"T3178","span":{"begin":4920,"end":4926},"obj":"NCBITaxon:39107"},{"id":"T3179","span":{"begin":5026,"end":5030},"obj":"SO:0000704"},{"id":"T3180","span":{"begin":5034,"end":5043},"obj":"CL:0000034"},{"id":"T3109","span":{"begin":292,"end":296},"obj":"CHEBI:22918"},{"id":"T3110","span":{"begin":674,"end":678},"obj":"CHEBI:22918"},{"id":"T3111","span":{"begin":682,"end":687},"obj":"UBERON:0000178"},{"id":"T3100","span":{"begin":11,"end":16},"obj":"NCBITaxon:4022"},{"id":"T3101","span":{"begin":23,"end":28},"obj":"UBERON:0001088"},{"id":"T3102","span":{"begin":49,"end":56},"obj":"SO:0000704"},{"id":"T3103","span":{"begin":107,"end":116},"obj":"CHEBI:25754"},{"id":"T3104","span":{"begin":142,"end":155},"obj":"GO:0005739"},{"id":"T3105","span":{"begin":168,"end":175},"obj":"GO:0032991"},{"id":"T3106","span":{"begin":196,"end":205},"obj":"MOP:0000568"},{"id":"T3107","span":{"begin":240,"end":250},"obj":"CHEBI:25754"},{"id":"T3108","span":{"begin":264,"end":290},"obj":"CHEBI:22918"},{"id":"T3112","span":{"begin":698,"end":709},"obj":"UBERON:0006314"},{"id":"T3113","span":{"begin":986,"end":990},"obj":"CHEBI:22918"},{"id":"T3114","span":{"begin":1120,"end":1125},"obj":"UBERON:0000178"},{"id":"T3115","span":{"begin":1126,"end":1130},"obj":"CHEBI:22918"},{"id":"T3116","span":{"begin":1357,"end":1370},"obj":"GO:0017086"},{"id":"T3117","span":{"begin":1464,"end":1477},"obj":"CHEBI:50488"},{"id":"T3118","span":{"begin":1492,"end":1494},"obj":"PR:000006300"},{"id":"T3119","span":{"begin":1503,"end":1516},"obj":"CHEBI:50488"},{"id":"T3121","span":{"begin":1590,"end":1591},"obj":"_FRAGMENT"},{"id":"T3122","span":{"begin":1602,"end":1610},"obj":"PR:000004686"}],"relations":[{"id":"R339","pred":"_lexicallyChainedTo","subj":"T3122","obj":"T3121"},{"id":"R340","pred":"_lexicallyChainedTo","subj":"T3128","obj":"T3127"},{"id":"R341","pred":"_lexicallyChainedTo","subj":"T3174","obj":"T3173"},{"id":"R342","pred":"_lexicallyChainedTo","subj":"T3174","obj":"T3175"}],"text":"Background\nMaple Syrup Urine Disease (MSUD) is a genetic disorder caused by a deficiency of branched-chain keto acid dehydrogenase (BCKDH), a mitochondrial multienzyme complex responsible for the oxidative decarboxylation of branched-chain keto acids derived from branched-chain amino acids (BCAA), leucine, isoleucine and valine (for review, see: [1]).\nPatients with MSUD, depending on the mutation, show variable degrees of enzyme deficiency leading to several different clinical phenotypes [1]. Approximately 75% of MSUD patients have the classic form of the disease with BCKDH activity in the range of 0–2% of normal [1]. These patients show markedly elevated levels of BCAA in blood and other body fluids [1]. Besides the classic form, there are other variants of the disease. Patients with the intermediate form of the disease show BCKDH activity in the range of 3–30% of normal. In such patients the onset of the disease is delayed, but there are persistently elevated levels of BCAA [1]. Patients with the intermittent form of MSUD show BCKDH activity in the range of 5–20% and during the asymptomatic phase the blood BCAA levels are normal [1]. The overall incidence of MSUD in the general population is 1:185,000 [1], and in certain population groups, such as Mennonites of Pennsylvania, the incidence is estimated to be as high as 1:176 [2].\nThe BCKDH complex, the deficient enzyme in MSUD, consists of three catalytic proteins, a decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoyl dehydrogenase (E3). The E1 component is a heterotetramer composed of two α and two β subunits [3]. The E1 and E2 components are specific to BCKDH, whereas E3 is also used by pyruvate and α-ketoglutarate dehydrogenase complexes [3] and the glycine cleavage system [4]. BCKDH is also associated with two regulatory proteins, a specific kinase and a phosphatase which regulate the activity of this enzyme through a phosphorylation (inactivation) and dephosphorylation (activation) cycle of the E1 α subunit [5,6]. Mutations in the genes of the E1 and E2 subunits of BCKDH have been described, however, the majority of MSUD mutations identified thus far are in the E2 subunit [1,7]. To date, cases of MSUD have not been associated with defects in the regulatory kinase and phosphatase [1].\nCurrent management of MSUD patients relies on a strict lifelong dietary restriction of protein or BCAA [1,8]. Such a dietary management of the disease, however, is not entirely satisfactory especially in times of metabolic decompensation due to infection, injuries and other stressors. In spite of dietary intervention, there is significant mortality associated with MSUD and there is a high incidence of mental retardation in survivors [9].\nBecause of the central role of the liver in amino acid metabolism and moderate/high levels of BCKDH activity in human liver [10-12], a few cases of MSUD have recently been treated by liver transplantation [13-16]. While the short-term outcome of liver transplantation is encouraging, long-term effects of this approach are not known. However, these patients are now required to take immunosuppressant drugs for the rest of their lives, often with undesirable side effects. Moreover, the cost associated with liver transplantation and the availability of donor livers are additional limiting factors for the practicality of treatment of this disease.\nBecause of the current unsatisfactory options for the treatment of MSUD, there is a need for improved therapies to combat this disease. An obstacle to developing novel treatments for MSUD has been the lack of a suitable animal model to perform necessary preclinical studies. Although a Hereford calf model with MSUD has been described [17-19], this model is neither readily available nor practical to perform preclinical studies. Furthermore, comparison of this animal model with human MSUD has shown some differences in the pathology of the disease [1], making this animal a less desirable model for the human disease.\nRecently, a N-ethyl-N-nitrosourea (ENU)-induced mutant mouse that phenotypically resembles human MSUD has been described [20]. However, the mutation in this model disrupts a splice site in the mitochondrial branched-chain aminotransferase (BCAT) gene, not in BCKDH, the deficient enzyme in MSUD. Because the mutation is not in BCKDH, the validity of this mutant mouse line for modeling human MSUD is questionable.\nThe objective of the present study was to create genetically engineered murine models of MSUD that mimic the pathology of the classic and intermediate variant forms of the human disease. The classic model was created by targeted inactivation of the E2 subunit of BCKDH by homologous recombination in embryonic stem (ES) cells. The model of intermediate MSUD was created by partial transgenic rescue of the E2 gene knockout. This report describes the generation and characterization of these murine models of MSUD. These models will allow for the development of novel treatment approaches, such as gene or stem cell therapies, to ultimately cure MSUD."}