PMC:1448208 / 1736-2102 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1448208","sourcedb":"PMC","sourceid":"1448208","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1448208","text":"These mice represent important animal models that closely approximate the phenotype of humans with the classic and intermediate forms of MSUD. These animals provide useful models to further characterize the pathogenesis of MSUD, as well as models to test novel therapeutic strategies, such as gene and cellular therapies, to treat this devastating metabolic disease.","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T1151","span":{"begin":0,"end":5},"obj":"DT"},{"id":"T1152","span":{"begin":6,"end":10},"obj":"NNS"},{"id":"T1153","span":{"begin":11,"end":20},"obj":"VBP"},{"id":"T1154","span":{"begin":21,"end":30},"obj":"JJ"},{"id":"T1155","span":{"begin":38,"end":44},"obj":"NNS"},{"id":"T1156","span":{"begin":31,"end":37},"obj":"NN"},{"id":"T1157","span":{"begin":45,"end":49},"obj":"WDT"},{"id":"T1158","span":{"begin":58,"end":69},"obj":"VBP"},{"id":"T1159","span":{"begin":50,"end":57},"obj":"RB"},{"id":"T1160","span":{"begin":70,"end":73},"obj":"DT"},{"id":"T1161","span":{"begin":74,"end":83},"obj":"NN"},{"id":"T1162","span":{"begin":84,"end":86},"obj":"IN"},{"id":"T1163","span":{"begin":87,"end":93},"obj":"NNS"},{"id":"T1164","span":{"begin":94,"end":98},"obj":"IN"},{"id":"T1165","span":{"begin":99,"end":102},"obj":"DT"},{"id":"T1166","span":{"begin":128,"end":133},"obj":"NNS"},{"id":"T1167","span":{"begin":103,"end":110},"obj":"JJ"},{"id":"T1168","span":{"begin":111,"end":114},"obj":"CC"},{"id":"T1169","span":{"begin":115,"end":127},"obj":"JJ"},{"id":"T1170","span":{"begin":134,"end":136},"obj":"IN"},{"id":"T1171","span":{"begin":137,"end":141},"obj":"NN"},{"id":"T1172","span":{"begin":141,"end":142},"obj":"."},{"id":"T1173","span":{"begin":142,"end":366},"obj":"sentence"},{"id":"T1174","span":{"begin":143,"end":148},"obj":"DT"},{"id":"T1175","span":{"begin":149,"end":156},"obj":"NNS"},{"id":"T1176","span":{"begin":157,"end":164},"obj":"VBP"},{"id":"T1177","span":{"begin":165,"end":171},"obj":"JJ"},{"id":"T1178","span":{"begin":172,"end":178},"obj":"NNS"},{"id":"T1179","span":{"begin":179,"end":181},"obj":"TO"},{"id":"T1180","span":{"begin":190,"end":202},"obj":"VB"},{"id":"T1181","span":{"begin":182,"end":189},"obj":"RB"},{"id":"T1182","span":{"begin":203,"end":206},"obj":"DT"},{"id":"T1183","span":{"begin":207,"end":219},"obj":"NN"},{"id":"T1184","span":{"begin":220,"end":222},"obj":"IN"},{"id":"T1185","span":{"begin":223,"end":227},"obj":"NN"},{"id":"T1186","span":{"begin":227,"end":229},"obj":","},{"id":"T1187","span":{"begin":229,"end":231},"obj":"RB"},{"id":"T1188","span":{"begin":237,"end":239},"obj":"IN"},{"id":"T1189","span":{"begin":232,"end":236},"obj":"RB"},{"id":"T1190","span":{"begin":240,"end":246},"obj":"NNS"},{"id":"T1191","span":{"begin":247,"end":249},"obj":"TO"},{"id":"T1192","span":{"begin":250,"end":254},"obj":"VB"},{"id":"T1193","span":{"begin":255,"end":260},"obj":"JJ"},{"id":"T1194","span":{"begin":273,"end":283},"obj":"NNS"},{"id":"T1195","span":{"begin":261,"end":272},"obj":"JJ"},{"id":"T1196","span":{"begin":283,"end":285},"obj":","},{"id":"T1197","span":{"begin":285,"end":289},"obj":"JJ"},{"id":"T1198","span":{"begin":290,"end":292},"obj":"IN"},{"id":"T1199","span":{"begin":293,"end":297},"obj":"NN"},{"id":"T1200","span":{"begin":311,"end":320},"obj":"NNS"},{"id":"T1201","span":{"begin":298,"end":301},"obj":"CC"},{"id":"T1202","span":{"begin":302,"end":310},"obj":"JJ"},{"id":"T1203","span":{"begin":320,"end":322},"obj":","},{"id":"T1204","span":{"begin":322,"end":324},"obj":"TO"},{"id":"T1205","span":{"begin":325,"end":330},"obj":"VB"},{"id":"T1206","span":{"begin":331,"end":335},"obj":"DT"},{"id":"T1207","span":{"begin":358,"end":365},"obj":"NN"},{"id":"T1208","span":{"begin":336,"end":347},"obj":"VBG"},{"id":"T1209","span":{"begin":348,"end":357},"obj":"JJ"},{"id":"T1210","span":{"begin":365,"end":366},"obj":"."}],"relations":[{"id":"R281","pred":"det","subj":"T1151","obj":"T1152"},{"id":"R282","pred":"nsubj","subj":"T1152","obj":"T1153"},{"id":"R283","pred":"amod","subj":"T1154","obj":"T1155"},{"id":"R284","pred":"dobj","subj":"T1155","obj":"T1153"},{"id":"R286","pred":"dep","subj":"T1157","obj":"T1158"},{"id":"R287","pred":"relcl","subj":"T1158","obj":"T1155"},{"id":"R289","pred":"det","subj":"T1160","obj":"T1161"},{"id":"R290","pred":"dobj","subj":"T1161","obj":"T1158"},{"id":"R291","pred":"prep","subj":"T1162","obj":"T1161"},{"id":"R292","pred":"pobj","subj":"T1163","obj":"T1162"},{"id":"R293","pred":"prep","subj":"T1164","obj":"T1163"},{"id":"R294","pred":"det","subj":"T1165","obj":"T1166"},{"id":"R295","pred":"pobj","subj":"T1166","obj":"T1164"},{"id":"R299","pred":"prep","subj":"T1170","obj":"T1166"},{"id":"R300","pred":"pobj","subj":"T1171","obj":"T1170"},{"id":"R301","pred":"punct","subj":"T1172","obj":"T1153"},{"id":"R302","pred":"det","subj":"T1174","obj":"T1175"},{"id":"R303","pred":"nsubj","subj":"T1175","obj":"T1176"},{"id":"R304","pred":"amod","subj":"T1177","obj":"T1178"},{"id":"R305","pred":"dobj","subj":"T1178","obj":"T1176"},{"id":"R306","pred":"aux","subj":"T1179","obj":"T1180"},{"id":"R307","pred":"advcl","subj":"T1180","obj":"T1178"},{"id":"R309","pred":"det","subj":"T1182","obj":"T1183"},{"id":"R310","pred":"dobj","subj":"T1183","obj":"T1180"},{"id":"R311","pred":"prep","subj":"T1184","obj":"T1183"},{"id":"R312","pred":"pobj","subj":"T1185","obj":"T1184"},{"id":"R313","pred":"punct","subj":"T1186","obj":"T1178"},{"id":"R314","pred":"advmod","subj":"T1187","obj":"T1188"},{"id":"R315","pred":"cc","subj":"T1188","obj":"T1178"},{"id":"R317","pred":"conj","subj":"T1190","obj":"T1178"},{"id":"R318","pred":"aux","subj":"T1191","obj":"T1192"},{"id":"R319","pred":"advcl","subj":"T1192","obj":"T1190"},{"id":"R320","pred":"amod","subj":"T1193","obj":"T1194"},{"id":"R321","pred":"dobj","subj":"T1194","obj":"T1192"},{"id":"R323","pred":"punct","subj":"T1196","obj":"T1194"},{"id":"R324","pred":"amod","subj":"T1197","obj":"T1198"},{"id":"R325","pred":"prep","subj":"T1198","obj":"T1194"},{"id":"R326","pred":"nmod","subj":"T1199","obj":"T1200"},{"id":"R327","pred":"pobj","subj":"T1200","obj":"T1198"},{"id":"R330","pred":"punct","subj":"T1203","obj":"T1200"},{"id":"R331","pred":"aux","subj":"T1204","obj":"T1205"},{"id":"R332","pred":"advcl","subj":"T1205","obj":"T1200"},{"id":"R333","pred":"det","subj":"T1206","obj":"T1207"},{"id":"R334","pred":"dobj","subj":"T1207","obj":"T1205"},{"id":"R337","pred":"punct","subj":"T1210","obj":"T1176"},{"id":"R285","pred":"compound","subj":"T1156","obj":"T1155"},{"id":"R288","pred":"advmod","subj":"T1159","obj":"T1158"},{"id":"R296","pred":"amod","subj":"T1167","obj":"T1166"},{"id":"R297","pred":"cc","subj":"T1168","obj":"T1167"},{"id":"R298","pred":"conj","subj":"T1169","obj":"T1167"},{"id":"R308","pred":"advmod","subj":"T1181","obj":"T1180"},{"id":"R316","pred":"advmod","subj":"T1189","obj":"T1188"},{"id":"R322","pred":"amod","subj":"T1195","obj":"T1194"},{"id":"R328","pred":"cc","subj":"T1201","obj":"T1199"},{"id":"R329","pred":"conj","subj":"T1202","obj":"T1199"},{"id":"R335","pred":"amod","subj":"T1208","obj":"T1207"},{"id":"R336","pred":"amod","subj":"T1209","obj":"T1207"}],"attributes":[{"subj":"T1151","pred":"source","obj":"craft-sa-dev"},{"subj":"T1152","pred":"source","obj":"craft-sa-dev"},{"subj":"T1153","pred":"source","obj":"craft-sa-dev"},{"subj":"T1154","pred":"source","obj":"craft-sa-dev"},{"subj":"T1155","pred":"source","obj":"craft-sa-dev"},{"subj":"T1156","pred":"source","obj":"craft-sa-dev"},{"subj":"T1157","pred":"source","obj":"craft-sa-dev"},{"subj":"T1158","pred":"source","obj":"craft-sa-dev"},{"subj":"T1159","pred":"source","obj":"craft-sa-dev"},{"subj":"T1160","pred":"source","obj":"craft-sa-dev"},{"subj":"T1161","pred":"source","obj":"craft-sa-dev"},{"subj":"T1162","pred":"source","obj":"craft-sa-dev"},{"subj":"T1163","pred":"source","obj":"craft-sa-dev"},{"subj":"T1164","pred":"source","obj":"craft-sa-dev"},{"subj":"T1165","pred":"source","obj":"craft-sa-dev"},{"subj":"T1166","pred":"source","obj":"craft-sa-dev"},{"subj":"T1167","pred":"source","obj":"craft-sa-dev"},{"subj":"T1168","pred":"source","obj":"craft-sa-dev"},{"subj":"T1169","pred":"source","obj":"craft-sa-dev"},{"subj":"T1170","pred":"source","obj":"craft-sa-dev"},{"subj":"T1171","pred":"source","obj":"craft-sa-dev"},{"subj":"T1172","pred":"source","obj":"craft-sa-dev"},{"subj":"T1173","pred":"source","obj":"craft-sa-dev"},{"subj":"T1174","pred":"source","obj":"craft-sa-dev"},{"subj":"T1175","pred":"source","obj":"craft-sa-dev"},{"subj":"T1176","pred":"source","obj":"craft-sa-dev"},{"subj":"T1177","pred":"source","obj":"craft-sa-dev"},{"subj":"T1178","pred":"source","obj":"craft-sa-dev"},{"subj":"T1179","pred":"source","obj":"craft-sa-dev"},{"subj":"T1180","pred":"source","obj":"craft-sa-dev"},{"subj":"T1181","pred":"source","obj":"craft-sa-dev"},{"subj":"T1182","pred":"source","obj":"craft-sa-dev"},{"subj":"T1183","pred":"source","obj":"craft-sa-dev"},{"subj":"T1184","pred":"source","obj":"craft-sa-dev"},{"subj":"T1185","pred":"source","obj":"craft-sa-dev"},{"subj":"T1186","pred":"source","obj":"craft-sa-dev"},{"subj":"T1187","pred":"source","obj":"craft-sa-dev"},{"subj":"T1188","pred":"source","obj":"craft-sa-dev"},{"subj":"T1189","pred":"source","obj":"craft-sa-dev"},{"subj":"T1190","pred":"source","obj":"craft-sa-dev"},{"subj":"T1191","pred":"source","obj":"craft-sa-dev"},{"subj":"T1192","pred":"source","obj":"craft-sa-dev"},{"subj":"T1193","pred":"source","obj":"craft-sa-dev"},{"subj":"T1194","pred":"source","obj":"craft-sa-dev"},{"subj":"T1195","pred":"source","obj":"craft-sa-dev"},{"subj":"T1196","pred":"source","obj":"craft-sa-dev"},{"subj":"T1197","pred":"source","obj":"craft-sa-dev"},{"subj":"T1198","pred":"source","obj":"craft-sa-dev"},{"subj":"T1199","pred":"source","obj":"craft-sa-dev"},{"subj":"T1200","pred":"source","obj":"craft-sa-dev"},{"subj":"T1201","pred":"source","obj":"craft-sa-dev"},{"subj":"T1202","pred":"source","obj":"craft-sa-dev"},{"subj":"T1203","pred":"source","obj":"craft-sa-dev"},{"subj":"T1204","pred":"source","obj":"craft-sa-dev"},{"subj":"T1205","pred":"source","obj":"craft-sa-dev"},{"subj":"T1206","pred":"source","obj":"craft-sa-dev"},{"subj":"T1207","pred":"source","obj":"craft-sa-dev"},{"subj":"T1208","pred":"source","obj":"craft-sa-dev"},{"subj":"T1209","pred":"source","obj":"craft-sa-dev"},{"subj":"T1210","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T827","span":{"begin":6,"end":10},"obj":"NCBITaxon:10088"},{"id":"T828","span":{"begin":31,"end":37},"obj":"NCBITaxon:33208"},{"id":"T829","span":{"begin":87,"end":93},"obj":"NCBITaxon:9606"},{"id":"T830","span":{"begin":149,"end":156},"obj":"NCBITaxon:33208"},{"id":"T831","span":{"begin":293,"end":297},"obj":"SO_EXT:0000704"},{"id":"T832","span":{"begin":302,"end":310},"obj":"CL_GO_EXT:cell"},{"id":"T833","span":{"begin":348,"end":357},"obj":"GO:0008152"}],"attributes":[{"subj":"T827","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T828","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T829","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T830","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T831","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T832","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T833","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T767","span":{"begin":6,"end":10},"obj":"NCBITaxon:10088"},{"id":"T768","span":{"begin":31,"end":37},"obj":"NCBITaxon:33208"},{"id":"T769","span":{"begin":87,"end":93},"obj":"NCBITaxon:9606"},{"id":"T770","span":{"begin":149,"end":156},"obj":"NCBITaxon:33208"},{"id":"T771","span":{"begin":293,"end":297},"obj":"SO:0000704"},{"id":"T772","span":{"begin":348,"end":357},"obj":"GO:0008152"}],"attributes":[{"subj":"T767","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T768","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T769","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T770","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T771","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T772","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#ec93d4","default":true},{"id":"craft-ca-core-ex-dev","color":"#93ecea"},{"id":"craft-ca-core-dev","color":"#ecd093"}]}]}}