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PMC:1448208 / 11540-12295 JSONTXT

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Id Subject Object Predicate Lexical cue
T6433 0-3 DT denotes The
T6434 30-35 NNS denotes lines
T6435 4-11 JJ denotes various
T6436 12-15 NN denotes TRE
T6437 16-18 NN denotes E2
T6438 15-16 HYPH denotes -
T6439 19-29 JJ denotes transgenic
T6440 50-55 VBN denotes mated
T6441 36-44 VBN denotes produced
T6442 45-49 VBD denotes were
T6443 56-69 RB denotes independently
T6444 70-72 IN denotes to
T6445 73-77 NNS denotes mice
T6446 78-82 WDT denotes that
T6447 83-87 VBD denotes were
T6448 88-100 JJ denotes heterozygous
T6449 101-104 IN denotes for
T6450 105-109 CC denotes both
T6451 117-125 NN denotes knockout
T6452 110-113 DT denotes the
T6453 114-116 NN denotes E2
T6454 126-129 CC denotes and
T6455 130-133 DT denotes the
T6456 142-151 NN denotes transgene
T6457 134-137 NN denotes LAP
T6458 138-141 NN denotes tTA
T6459 137-138 HYPH denotes -
T6460 152-153 -LRB- denotes [
T6461 244-254 NN denotes background
T6462 153-155 NN denotes Tg
T6463 170-175 NN denotes Stock
T6464 155-156 -LRB- denotes (
T6465 156-162 NN denotes tTALap
T6466 162-163 -RRB- denotes )
T6467 163-166 NN denotes Bjd
T6468 167-168 NN denotes J
T6469 166-167 HYPH denotes /
T6470 168-169 : denotes ;
T6471 176-180 CD denotes 3272
T6472 180-181 : denotes ;
T6473 182-185 DT denotes The
T6474 194-204 NNP denotes Laboratory
T6475 186-193 NNP denotes Jackson
T6476 204-206 , denotes ,
T6477 206-209 NNP denotes Bar
T6478 210-216 NNP denotes Harbor
T6479 216-218 , denotes ,
T6480 218-220 NNP denotes ME
T6481 220-221 : denotes ;
T6482 222-226 NN denotes NMRI
T6483 227-228 SYM denotes ×
T6484 229-232 NN denotes FVB
T6485 233-234 SYM denotes ×
T6486 235-240 NN denotes C57BL
T6487 241-243 NN denotes 6J
T6488 240-241 HYPH denotes /
T6489 254-255 -RRB- denotes ]
T6490 255-256 . denotes .
T6491 256-557 sentence denotes Interbreeding of animals that were heterozygous for both transgenes and the knockout resulted in the production of mice with a variety of genotypes including some animals that were homozygous for the knockout and were positive for both transgenes (we refer to this genotype as the "rescue" genotype).
T6492 257-270 NN denotes Interbreeding
T6493 342-350 VBD denotes resulted
T6494 271-273 IN denotes of
T6495 274-281 NNS denotes animals
T6496 282-286 WDT denotes that
T6497 287-291 VBD denotes were
T6498 292-304 JJ denotes heterozygous
T6499 305-308 IN denotes for
T6500 309-313 DT denotes both
T6501 314-324 NNS denotes transgenes
T6502 325-328 CC denotes and
T6503 329-332 DT denotes the
T6504 333-341 NN denotes knockout
T6505 351-353 IN denotes in
T6506 354-357 DT denotes the
T6507 358-368 NN denotes production
T6508 369-371 IN denotes of
T6509 372-376 NNS denotes mice
T6510 377-381 IN denotes with
T6511 382-383 DT denotes a
T6512 384-391 NN denotes variety
T6513 392-394 IN denotes of
T6514 395-404 NNS denotes genotypes
T6515 405-414 VBG denotes including
T6516 415-419 DT denotes some
T6517 420-427 NNS denotes animals
T6518 428-432 WDT denotes that
T6519 433-437 VBD denotes were
T6520 438-448 JJ denotes homozygous
T6521 449-452 IN denotes for
T6522 453-456 DT denotes the
T6523 457-465 NN denotes knockout
T6524 466-469 CC denotes and
T6525 470-474 VBD denotes were
T6526 475-483 JJ denotes positive
T6527 484-487 IN denotes for
T6528 488-492 DT denotes both
T6529 493-503 NNS denotes transgenes
T6530 504-505 -LRB- denotes (
T6531 508-513 VBP denotes refer
T6532 505-507 PRP denotes we
T6533 514-516 IN denotes to
T6534 517-521 DT denotes this
T6535 522-530 NN denotes genotype
T6536 531-533 IN denotes as
T6537 534-537 DT denotes the
T6538 547-555 NN denotes genotype
T6539 538-539 `` denotes "
T6540 539-545 NN denotes rescue
T6541 545-546 '' denotes "
T6542 555-556 -RRB- denotes )
T6543 556-557 . denotes .
T6544 557-755 sentence denotes If our strategy for rescuing the neonatal lethal phenotype of the knockout were successful, then those homozygous knockout animals that had both transgenes would survive beyond the neonatal period.
T6545 558-560 IN denotes If
T6546 633-637 VBD denotes were
T6547 561-564 PRP$ denotes our
T6548 565-573 NN denotes strategy
T6549 574-577 IN denotes for
T6550 578-586 VBG denotes rescuing
T6551 587-590 DT denotes the
T6552 607-616 NN denotes phenotype
T6553 591-599 JJ denotes neonatal
T6554 600-606 JJ denotes lethal
T6555 617-619 IN denotes of
T6556 620-623 DT denotes the
T6557 624-632 NN denotes knockout
T6558 720-727 VB denotes survive
T6559 638-648 JJ denotes successful
T6560 648-650 , denotes ,
T6561 650-654 RB denotes then
T6562 655-660 DT denotes those
T6563 681-688 NNS denotes animals
T6564 661-671 JJ denotes homozygous
T6565 672-680 NN denotes knockout
T6566 689-693 WDT denotes that
T6567 694-697 VBD denotes had
T6568 698-702 DT denotes both
T6569 703-713 NNS denotes transgenes
T6570 714-719 MD denotes would
T6571 728-734 IN denotes beyond
T6572 735-738 DT denotes the
T6573 748-754 NN denotes period
T6574 739-747 JJ denotes neonatal
T6575 754-755 . denotes .
R1833 T6433 T6434 det The,lines
R1834 T6434 T6440 nsubjpass lines,mated
R1835 T6435 T6434 amod various,lines
R1836 T6436 T6437 nmod TRE,E2
R1837 T6437 T6434 nmod E2,lines
R1838 T6438 T6437 punct -,E2
R1839 T6439 T6434 amod transgenic,lines
R1840 T6441 T6434 acl produced,lines
R1841 T6442 T6440 auxpass were,mated
R1842 T6443 T6440 advmod independently,mated
R1843 T6444 T6440 prep to,mated
R1844 T6445 T6444 pobj mice,to
R1845 T6446 T6447 dep that,were
R1846 T6447 T6445 relcl were,mice
R1847 T6448 T6447 acomp heterozygous,were
R1848 T6449 T6448 prep for,heterozygous
R1849 T6450 T6451 preconj both,knockout
R1850 T6451 T6449 pobj knockout,for
R1851 T6452 T6451 det the,knockout
R1852 T6453 T6451 compound E2,knockout
R1853 T6454 T6451 cc and,knockout
R1854 T6455 T6456 det the,transgene
R1855 T6456 T6451 conj transgene,knockout
R1856 T6457 T6458 compound LAP,tTA
R1857 T6458 T6456 compound tTA,transgene
R1858 T6459 T6458 punct -,tTA
R1859 T6460 T6461 punct [,background
R1860 T6461 T6440 parataxis background,mated
R1861 T6462 T6463 nmod Tg,Stock
R1862 T6463 T6461 dep Stock,background
R1863 T6464 T6465 punct (,tTALap
R1864 T6465 T6463 parataxis tTALap,Stock
R1865 T6466 T6465 punct ),tTALap
R1866 T6467 T6468 nmod Bjd,J
R1867 T6468 T6463 nmod J,Stock
R1868 T6469 T6468 punct /,J
R1869 T6470 T6463 punct ;,Stock
R1870 T6471 T6463 nummod 3272,Stock
R1871 T6472 T6461 punct ;,background
R1872 T6473 T6474 det The,Laboratory
R1873 T6474 T6461 dep Laboratory,background
R1874 T6475 T6474 compound Jackson,Laboratory
R1875 T6476 T6474 punct ", ",Laboratory
R1876 T6477 T6478 compound Bar,Harbor
R1877 T6478 T6474 npadvmod Harbor,Laboratory
R1878 T6479 T6474 punct ", ",Laboratory
R1879 T6480 T6474 npadvmod ME,Laboratory
R1880 T6481 T6461 punct ;,background
R1881 T6482 T6461 nmod NMRI,background
R1882 T6483 T6482 punct ×,NMRI
R1883 T6484 T6482 appos FVB,NMRI
R1884 T6485 T6482 punct ×,NMRI
R1885 T6486 T6487 compound C57BL,6J
R1886 T6487 T6482 appos 6J,NMRI
R1887 T6488 T6487 punct /,6J
R1888 T6489 T6461 punct ],background
R1889 T6490 T6440 punct .,mated
R1890 T6492 T6493 nsubj Interbreeding,resulted
R1891 T6494 T6492 prep of,Interbreeding
R1892 T6495 T6494 pobj animals,of
R1893 T6496 T6497 dep that,were
R1894 T6497 T6495 relcl were,animals
R1895 T6498 T6497 acomp heterozygous,were
R1896 T6499 T6498 prep for,heterozygous
R1897 T6500 T6501 det both,transgenes
R1898 T6501 T6499 pobj transgenes,for
R1899 T6502 T6501 cc and,transgenes
R1900 T6503 T6504 det the,knockout
R1901 T6504 T6501 conj knockout,transgenes
R1902 T6505 T6493 prep in,resulted
R1903 T6506 T6507 det the,production
R1904 T6507 T6505 pobj production,in
R1905 T6508 T6507 prep of,production
R1906 T6509 T6508 pobj mice,of
R1907 T6510 T6509 prep with,mice
R1908 T6511 T6512 det a,variety
R1909 T6512 T6510 pobj variety,with
R1910 T6513 T6512 prep of,variety
R1911 T6514 T6513 pobj genotypes,of
R1912 T6515 T6509 prep including,mice
R1913 T6516 T6517 det some,animals
R1914 T6517 T6515 pobj animals,including
R1915 T6518 T6519 dep that,were
R1916 T6519 T6517 relcl were,animals
R1917 T6520 T6519 acomp homozygous,were
R1918 T6521 T6520 prep for,homozygous
R1919 T6522 T6523 det the,knockout
R1920 T6523 T6521 pobj knockout,for
R1921 T6524 T6519 cc and,were
R1922 T6525 T6519 conj were,were
R1923 T6526 T6525 acomp positive,were
R1924 T6527 T6526 prep for,positive
R1925 T6528 T6529 det both,transgenes
R1926 T6529 T6527 pobj transgenes,for
R1927 T6530 T6531 punct (,refer
R1928 T6531 T6525 parataxis refer,were
R1929 T6532 T6531 nsubj we,refer
R1930 T6533 T6531 prep to,refer
R1931 T6534 T6535 det this,genotype
R1932 T6535 T6533 pobj genotype,to
R1933 T6536 T6531 prep as,refer
R1934 T6537 T6538 det the,genotype
R1935 T6538 T6536 pobj genotype,as
R1936 T6539 T6538 punct """",genotype
R1937 T6540 T6538 nmod rescue,genotype
R1938 T6541 T6538 punct """",genotype
R1939 T6542 T6531 punct ),refer
R1940 T6543 T6493 punct .,resulted
R1941 T6545 T6546 mark If,were
R1942 T6546 T6558 advcl were,survive
R1943 T6547 T6548 poss our,strategy
R1944 T6548 T6546 nsubj strategy,were
R1945 T6549 T6548 prep for,strategy
R1946 T6550 T6549 pcomp rescuing,for
R1947 T6551 T6552 det the,phenotype
R1948 T6552 T6550 dobj phenotype,rescuing
R1949 T6553 T6552 amod neonatal,phenotype
R1950 T6554 T6552 amod lethal,phenotype
R1951 T6555 T6552 prep of,phenotype
R1952 T6556 T6557 det the,knockout
R1953 T6557 T6555 pobj knockout,of
R1954 T6559 T6546 acomp successful,were
R1955 T6560 T6558 punct ", ",survive
R1956 T6561 T6558 advmod then,survive
R1957 T6562 T6563 det those,animals
R1958 T6563 T6558 nsubj animals,survive
R1959 T6564 T6563 amod homozygous,animals
R1960 T6565 T6563 compound knockout,animals
R1961 T6566 T6567 dep that,had
R1962 T6567 T6563 relcl had,animals
R1963 T6568 T6569 det both,transgenes
R1964 T6569 T6567 dobj transgenes,had
R1965 T6570 T6558 aux would,survive
R1966 T6571 T6558 prep beyond,survive
R1967 T6572 T6573 det the,period
R1968 T6573 T6571 pobj period,beyond
R1969 T6574 T6573 amod neonatal,period
R1970 T6575 T6558 punct .,survive

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6402 16-18 PR_EXT:000006300 denotes E2
T6403 19-29 SO_EXT:transgenic_entity denotes transgenic
T6404 50-55 GO:0007618 denotes mated
T6405 73-77 NCBITaxon:10088 denotes mice
T6406 114-116 PR_EXT:000006300 denotes E2
T6407 134-137 PR_EXT:000005308 denotes LAP
T6408 142-151 SO_EXT:0000902 denotes transgene
T6409 153-155 SO_EXT:transgenic_entity denotes Tg
T6410 262-270 GO_EXT:breeding denotes breeding
T6411 274-281 NCBITaxon:33208 denotes animals
T6412 314-324 SO_EXT:0000902 denotes transgenes
T6413 372-376 NCBITaxon:10088 denotes mice
T6414 395-404 SO_EXT:genotype_or_entity_with_genotype denotes genotypes
T6415 420-427 NCBITaxon:33208 denotes animals
T6416 493-503 SO_EXT:0000902 denotes transgenes
T6417 522-530 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T6418 539-545 SO_EXT:sequence_rescue_process denotes rescue
T6419 547-555 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T6420 578-586 SO_EXT:sequence_rescue_process denotes rescuing
T6421 591-599 PATO_UBERON_EXT:neonate_or_newborn denotes neonatal
T6422 600-606 GO_EXT:fatality_or_lethality denotes lethal
T6423 681-688 NCBITaxon:33208 denotes animals
T6424 703-713 SO_EXT:0000902 denotes transgenes
T6425 739-754 UBERON:0007221 denotes neonatal period

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6387 16-18 PR:000006300 denotes E2
T6388 50-55 GO:0007618 denotes mated
T6389 73-77 NCBITaxon:10088 denotes mice
T6390 114-116 PR:000006300 denotes E2
T6391 134-137 PR:000005308 denotes LAP
T6392 142-151 SO:0000902 denotes transgene
T6393 274-281 NCBITaxon:33208 denotes animals
T6394 314-324 SO:0000902 denotes transgenes
T6395 372-376 NCBITaxon:10088 denotes mice
T6396 420-427 NCBITaxon:33208 denotes animals
T6397 493-503 SO:0000902 denotes transgenes
T6398 681-688 NCBITaxon:33208 denotes animals
T6399 703-713 SO:0000902 denotes transgenes
T6400 739-754 UBERON:0007221 denotes neonatal period