PMC:1447668 / 17683-23570 JSON TXT

Annnotations TAB JSON ListView MergeView

bionlp-st-ge-2016-reference-tees

Id	Subject	Object	Predicate	Lexical cue
T8837	33-43	Protein	denotes	HTLV-I Tax
T8838	135-140	Protein	denotes	Foxp3
T8839	178-183	Protein	denotes	NF-κB
T8840	206-229	Protein	denotes	tumor necrosis factor-α
T8841	241-246	Protein	denotes	NF-κB
T8842	184-194	Positive_regulation	denotes	activation
T8843	145-152	Negative_regulation	denotes	repress
T8844	303-308	Protein	denotes	Foxp3
T8845	347-352	Protein	denotes	NF-κB
T8846	372-400	Protein	denotes	viral transactivator protein
T8847	333-343	Positive_regulation	denotes	activation
T8848	459-462	Protein	denotes	Tax
T8849	495-500	Protein	denotes	NF-κB
T8850	505-509	Protein	denotes	CREB
T8851	545-548	Protein	denotes	Tax
T8852	654-659	Protein	denotes	NF-κB
T8853	708-713	Protein	denotes	Foxp3
T8854	640-650	Positive_regulation	denotes	activation
T8855	690-704	Positive_regulation	denotes	overexpression
T8856	762-765	Protein	denotes	Tax
T8857	817-822	Protein	denotes	NF-κB
T8858	855-860	Protein	denotes	Foxp3
T8859	878-881	Protein	denotes	Tax
T8860	910-920	Protein	denotes	HTLV-I LTR
T8861	892-902	Positive_regulation	denotes	activation
T8862	871-877	Regulation	denotes	affect
T8863	965-975	Protein	denotes	HTLV-I Tax
T8864	989-994	Protein	denotes	Foxp3
T8865	1011-1019	Protein	denotes	HEK 293T
T8866	1062-1067	Protein	denotes	NF-κB
T8867	951-964	Positive_regulation	denotes	overexpressed
T8868	951-964	Positive_regulation	denotes	overexpressed
T8869	1115-1118	Protein	denotes	Tax
T8870	1141-1146	Protein	denotes	NF-κB
T8871	1229-1234	Protein	denotes	Foxp3
T8872	1244-1248	Protein	denotes	ΔFKH
T8873	1261-1264	Protein	denotes	Tax
T8874	1288-1293	Protein	denotes	NF-κB
T8875	1211-1225	Gene_expression	denotes	overexpression
T8876	1211-1225	Gene_expression	denotes	overexpression
T8877	1274-1284	Positive_regulation	denotes	activation
T8878	1274-1284	Positive_regulation	denotes	activation
T8879	1433-1438	Protein	denotes	NF-κB
T8880	1458-1461	Protein	denotes	Tax
T8881	1465-1473	Protein	denotes	HEK 293T
T8882	1523-1528	Protein	denotes	Foxp3
T8883	1543-1551	Protein	denotes	basal NF
T8884	1552-1554	Protein	denotes	κB
T8885	1419-1429	Positive_regulation	denotes	activation
T8886	1529-1539	Negative_regulation	denotes	inhibition
T8887	1555-1565	Positive_regulation	denotes	activation
T8888	1555-1565	Positive_regulation	denotes	activation
T8889	1408-1418	Negative_regulation	denotes	inhibiting
T8890	1529-1539	Negative_regulation	denotes	inhibition
T8891	1529-1539	Negative_regulation	denotes	inhibition
T8892	1609-1619	Protein	denotes	HTLV-I LTR
T8893	1670-1673	Protein	denotes	Tax
T8894	1709-1714	Protein	denotes	Foxp3
T8895	1726-1729	Protein	denotes	Tax
T8896	1824-1827	Protein	denotes	Tax
T8897	1846-1851	Protein	denotes	NF-κB
T8898	1855-1860	Protein	denotes	NF-AT
T8899	1919-1924	Protein	denotes	Foxp3
T8900	1652-1666	Positive_regulation	denotes	overexpression
T8901	1693-1705	Gene_expression	denotes	transfection
T8902	1905-1913	Binding	denotes	interact
T8903	1586-1601	Positive_regulation	denotes	Transactivation
T8904	1958-1962	Protein	denotes	ΔFKH
T8905	2016-2019	Protein	denotes	Tax
T8906	1940-1954	Positive_regulation	denotes	overexpression
T8907	2147-2152	Protein	denotes	Foxp3
T8908	2203-2206	Protein	denotes	Tax
T8909	2173-2183	Gene_expression	denotes	expression
T8910	2153-2168	Negative_regulation	denotes	down-regulating
T8911	2298-2303	Protein	denotes	Foxp3
T8912	2361-2366	Protein	denotes	NF-κB
T8913	2371-2376	Protein	denotes	NF-AT
T8914	2499-2502	Protein	denotes	Tax
T8915	2304-2313	Binding	denotes	interacts
T8916	2304-2313	Binding	denotes	interacts
T8917	2304-2313	Binding	denotes	interacts
T8918	2455-2462	Entity	denotes	nucleus
T8919	3860-3865	Protein	denotes	Foxp3
T8920	3909-3912	Protein	denotes	Tax
T8921	4012-4015	Protein	denotes	Tax
T8922	4067-4090	Protein	denotes	Gal4 DNA-binding domain
T8923	4092-4099	Protein	denotes	Gal4-BD
T8924	3925-3936	Binding	denotes	associating
T8925	4107-4111	Protein	denotes	Gal4
T8926	4112-4114	Protein	denotes	BD
T8927	4115-4118	Protein	denotes	Tax
T8928	4198-4202	Protein	denotes	Gal4
T8929	4224-4231	Protein	denotes	Gal4-BD
T8930	4134-4143	Positive_regulation	denotes	activated
T8931	4322-4345	Protein	denotes	Gal4-resposive promoter
T8932	4349-4360	Protein	denotes	Gal4-BD-Tax
T8933	4420-4424	Protein	denotes	EGFP
T8934	4436-4441	Protein	denotes	Foxp3
T8935	4468-4473	Protein	denotes	Foxp3
T8936	4491-4494	Protein	denotes	Tax
T8937	4544-4562	Protein	denotes	HTLV-I Tax protein
T8938	4395-4409	Positive_regulation	denotes	overexpression
T8939	4395-4409	Positive_regulation	denotes	overexpression
T8940	4523-4534	Binding	denotes	interfacing
T8941	4580-4585	Protein	denotes	Foxp3
T8942	4768-4773	Protein	denotes	Foxp3
T8943	4775-4779	Protein	denotes	ΔFKH
T8944	4914-4917	Protein	denotes	CD4
T8945	5027-5030	Protein	denotes	Tax
T8946	5130-5138	Protein	denotes	Tax mRNA
T8947	5156-5159	Protein	denotes	ACH
T8948	5198-5203	Protein	denotes	Foxp3
T8949	5139-5150	Gene_expression	denotes	synthesized
T8950	5139-5150	Gene_expression	denotes	synthesized
T8951	5164-5178	Negative_regulation	denotes	down-regulated
T8952	5164-5178	Negative_regulation	denotes	down-regulated
T8953	5226-5234	Transcription	denotes	produced
T8954	5316-5319	Protein	denotes	Tax
T8955	5320-5330	Gene_expression	denotes	expression
T8956	5306-5312	Regulation	denotes	affect
T8957	5357-5362	Protein	denotes	Foxp3
T8958	5406-5409	Protein	denotes	Tax
T8959	5392-5402	Gene_expression	denotes	expression
T8960	5377-5387	Negative_regulation	denotes	repressing
R6771	T8838	T8843	causeOf	Foxp3,repress
R6772	T8839	T8842	themeOf	NF-κB,activation
R6774	T8842	T8843	themeOf	activation,repress
R6775	T8845	T8847	themeOf	NF-κB,activation
R6776	T8852	T8854	themeOf	NF-κB,activation
R6778	T8853	T8855	themeOf	Foxp3,overexpression
R6781	T8858	T8862	causeOf	Foxp3,affect
R6782	T8859	T8861	causeOf	Tax,activation
R6783	T8860	T8861	themeOf	HTLV-I LTR,activation
R6784	T8861	T8862	themeOf	activation,affect
R6786	T8863	T8867	themeOf	HTLV-I Tax,overexpressed
R6787	T8864	T8868	themeOf	Foxp3,overexpressed
R6789	T8871	T8875	themeOf	Foxp3,overexpression
R6790	T8872	T8876	themeOf	ΔFKH,overexpression
R6792	T8873	T8877	causeOf	Tax,activation
R6793	T8873	T8878	causeOf	Tax,activation
R6795	T8875	T8877	themeOf	overexpression,activation
R6796	T8876	T8878	themeOf	overexpression,activation
R6798	T8879	T8885	themeOf	NF-κB,activation
R6799	T8880	T8889	causeOf	Tax,inhibiting
R6801	T8882	T8886	themeOf	Foxp3,inhibition
R6802	T8883	T8887	themeOf	basal NF,activation
R6803	T8884	T8888	themeOf	κB,activation
R6804	T8885	T8889	themeOf	activation,inhibiting
R6806	T8887	T8890	themeOf	activation,inhibition
R6807	T8888	T8891	themeOf	activation,inhibition
R6809	T8892	T8903	themeOf	HTLV-I LTR,Transactivation
R6810	T8893	T8900	themeOf	Tax,overexpression
R6811	T8894	T8901	themeOf	Foxp3,transfection
R6814	T8899	T8902	themeOf	Foxp3,interact
R6815	T8900	T8903	causeOf	overexpression,Transactivation
R6817	T8904	T8906	themeOf	ΔFKH,overexpression
R6818	T8907	T8910	causeOf	Foxp3,down-regulating
R6819	T8908	T8909	themeOf	Tax,expression
R6820	T8909	T8910	themeOf	expression,down-regulating
R6821	T8911	T8915	themeOf	Foxp3,interacts
R6822	T8911	T8916	themeOf	Foxp3,interacts
R6823	T8911	T8917	themeOf	Foxp3,interacts
R6824	T8912	T8916	themeOf	NF-κB,interacts
R6825	T8913	T8917	themeOf	NF-AT,interacts
R6826	T8919	T8924	themeOf	Foxp3,associating
R6827	T8920	T8924	themeOf	Tax,associating
R6828	T8927	T8930	themeOf	Tax,activated
R6829	T8933	T8938	themeOf	EGFP,overexpression
R6830	T8934	T8939	themeOf	Foxp3,overexpression
R6831	T8935	T8940	themeOf	Foxp3,interfacing
R6832	T8937	T8940	themeOf	HTLV-I Tax protein,interfacing
R6833	T8946	T8949	themeOf	Tax mRNA,synthesized
R6834	T8946	T8953	themeOf	Tax mRNA,produced
R6835	T8947	T8950	themeOf	ACH,synthesized
R6836	T8949	T8951	themeOf	synthesized,down-regulated
R6837	T8950	T8952	themeOf	synthesized,down-regulated
R6838	T8954	T8955	themeOf	Tax,expression
R6839	T8955	T8956	themeOf	expression,affect
R6840	T8957	T8960	causeOf	Foxp3,repressing
R6841	T8958	T8959	themeOf	Tax,expression
R6842	T8959	T8960	themeOf	expression,repressing

sentences

Id	Subject	Object	Predicate	Lexical cue
T6788	0-67	Sentence	denotes	The Transactivation Functions of HTLV-I Tax Are Suppressed by Foxp3
T6789	68-263	Sentence	denotes	Previous studies by Bettelli and colleagues have demonstrated that Foxp3 can repress both the basal levels of NF-κB activation as well as tumor necrosis factor-α-stimulated NF-κB activation [15].
T6790	264-401	Sentence	denotes	Our next step was to determine whether Foxp3 could also suppress the activation of NF-κB caused by a strong viral transactivator protein.
T6791	402-527	Sentence	denotes	HTLV-I encodes a multifunctional transactivator protein, Tax, capable of activating both the NF-κB and CREB pathways [24–29].
T6792	528-746	Sentence	denotes	Since the HTLV-I Tax protein can function at multiple levels in both the cytoplasm and the nucleus to stimulate activation of NF-κB [28,29], we hypothesized that overexpression of Foxp3 may interfere with this process.
T6793	747-921	Sentence	denotes	However, since Tax-dependent HTLV-I gene expression is independent of NF-κB [18], we also hypothesized that Foxp3 would not affect Tax-dependent activation of the HTLV-I LTR.
T6794	922-1084	Sentence	denotes	To test these hypotheses, we overexpressed HTLV-I Tax, full-length Foxp3, and/or ΔFKH in HEK 293T cells cotransfected with an HTLV-I LTR or NF-κB reporter vector.
T6795	1085-1195	Sentence	denotes	As shown in Figure 4A, HTLV-I Tax strongly up-regulated NF-κB-dependent transcriptional activation (~60-fold).
T6796	1196-1318	Sentence	denotes	Interestingly, overexpression of Foxp3, but not ΔFKH, suppressed Tax-mediated activation of NF-κB-dependent transcription.
T6797	1319-1585	Sentence	denotes	These observations further suggest that the carboxyl-terminal FKH domain is required for inhibiting activation of NF-κB in the presence of Tax in HEK 293T cells, strikingly similar to the requirements of Foxp3 inhibition of basal NF-κB activation shown in Figure 2B.
T6798	1586-1926	Sentence	denotes	Transactivation of the HTLV-I LTR was stimulated about 55-fold by overexpression of Tax (Figure 4B), while transfection of Foxp3 suppressed Tax-dependent HTLV-I LTR activation, although HTLV-I LTR activation in the presence or absence of Tax is independent of NF-κB or NF-AT (another transcriptional activator known to interact with Foxp3).
T6799	1927-2073	Sentence	denotes	Furthermore, overexpression of ΔFKH also led to suppression of HTLV-I transactivation by Tax to a similar extent as full-length Foxp3 (Figure 4B).
T6800	2074-2261	Sentence	denotes	The suppressive effects shown in Figure 4A and 4B were not the result of Foxp3 down-regulating the expression of the transfected Tax plasmid as determined by real-time RT-PCR (Figure 4C).
T6801	2262-2559	Sentence	denotes	These results strongly suggest that Foxp3 interacts with transcriptional regulators in addition to NF-κB and NF-AT, and that the carboxyl-terminal FKH domain, and therefore localization to the nucleus, are not required for inhibition of Tax-mediated HTLV-I LTR activation (even in HEK 293T cells).
T6802	3839-4101	Sentence	denotes	To determine whether Foxp3 inhibited the transactivation functions of Tax by directly associating with this viral protein, we generated an expression vector in which HTLV-I Tax was fused in-frame to the carboxyl terminus of the Gal4 DNA-binding domain (Gal4-BD).
T6803	4102-4298	Sentence	denotes	This Gal4-BD-Tax fusion protein activated transcription of a synthetic promoter containing five Gal4 binding sites, while Gal4-BD was insufficient to stimulate transcription by itself (Figure 4D).
T6804	4299-4563	Sentence	denotes	Transactivation of the Gal4-resposive promoter by Gal4-BD-Tax remained relatively unaffected by overexpression of either EGFP (control), Foxp3, or ΔFKH, suggesting that Foxp3 does not repress Tax transactivation by directly interfacing with the HTLV-I Tax protein.
T6805	4564-4799	Sentence	denotes	To confirm that Foxp3 had a direct effect on HTLV-I replication, we transfected HEK 293T cells with a well-characterized HTLV-I infectious molecular clone (termed ACH) [30] in the presence of full-length Foxp3, ΔFKH, or control vector.
T6806	4800-4961	Sentence	denotes	ACH has been previously shown to direct the expression of viral antigens, produce infectious virus, and transform CD4+ T cells both in vitro and in vivo [31,32].
T6807	4962-5088	Sentence	denotes	After 24 h, the amount of viral antigen expression, in this case Tax mRNA, was detected by a sensitive real-time RT-PCR assay.
T6808	5089-5331	Sentence	denotes	As illustrated in Figure 5, the level of Tax mRNA synthesized from ACH was down-regulated in the presence of Foxp3 compared to the level produced in the presence of the control vector. ΔFKH did not have a discernable affect on Tax expression.
T6809	5332-5452	Sentence	denotes	These data indicate that Foxp3 is capable of repressing the expression of Tax from an infectious HTLV-I molecular clone.
T97	0-67	Sentence	denotes	The Transactivation Functions of HTLV-I Tax Are Suppressed by Foxp3
T98	68-263	Sentence	denotes	Previous studies by Bettelli and colleagues have demonstrated that Foxp3 can repress both the basal levels of NF-κB activation as well as tumor necrosis factor-α-stimulated NF-κB activation [15].
T99	264-401	Sentence	denotes	Our next step was to determine whether Foxp3 could also suppress the activation of NF-κB caused by a strong viral transactivator protein.
T100	402-527	Sentence	denotes	HTLV-I encodes a multifunctional transactivator protein, Tax, capable of activating both the NF-κB and CREB pathways [24–29].
T101	528-746	Sentence	denotes	Since the HTLV-I Tax protein can function at multiple levels in both the cytoplasm and the nucleus to stimulate activation of NF-κB [28,29], we hypothesized that overexpression of Foxp3 may interfere with this process.
T102	747-921	Sentence	denotes	However, since Tax-dependent HTLV-I gene expression is independent of NF-κB [18], we also hypothesized that Foxp3 would not affect Tax-dependent activation of the HTLV-I LTR.
T103	922-1084	Sentence	denotes	To test these hypotheses, we overexpressed HTLV-I Tax, full-length Foxp3, and/or ΔFKH in HEK 293T cells cotransfected with an HTLV-I LTR or NF-κB reporter vector.
T104	1085-1195	Sentence	denotes	As shown in Figure 4A, HTLV-I Tax strongly up-regulated NF-κB-dependent transcriptional activation (~60-fold).
T105	1196-1318	Sentence	denotes	Interestingly, overexpression of Foxp3, but not ΔFKH, suppressed Tax-mediated activation of NF-κB-dependent transcription.
T106	1319-1585	Sentence	denotes	These observations further suggest that the carboxyl-terminal FKH domain is required for inhibiting activation of NF-κB in the presence of Tax in HEK 293T cells, strikingly similar to the requirements of Foxp3 inhibition of basal NF-κB activation shown in Figure 2B.
T107	1586-1926	Sentence	denotes	Transactivation of the HTLV-I LTR was stimulated about 55-fold by overexpression of Tax (Figure 4B), while transfection of Foxp3 suppressed Tax-dependent HTLV-I LTR activation, although HTLV-I LTR activation in the presence or absence of Tax is independent of NF-κB or NF-AT (another transcriptional activator known to interact with Foxp3).
T108	1927-2073	Sentence	denotes	Furthermore, overexpression of ΔFKH also led to suppression of HTLV-I transactivation by Tax to a similar extent as full-length Foxp3 (Figure 4B).
T109	2074-2261	Sentence	denotes	The suppressive effects shown in Figure 4A and 4B were not the result of Foxp3 down-regulating the expression of the transfected Tax plasmid as determined by real-time RT-PCR (Figure 4C).
T110	2262-2559	Sentence	denotes	These results strongly suggest that Foxp3 interacts with transcriptional regulators in addition to NF-κB and NF-AT, and that the carboxyl-terminal FKH domain, and therefore localization to the nucleus, are not required for inhibition of Tax-mediated HTLV-I LTR activation (even in HEK 293T cells).
T111	2560-2648	Sentence	denotes	Figure 4 Transactivation Functions of HTLV-I Tax Are Blocked by Overexpression of Foxp3
T112	2649-2963	Sentence	denotes	(A and B) HEK 293T cells (5 × 105) were seeded into six-well plates 1 d prior to transfection with NF-κB (A) or HTLV-I LTR (B) luciferase reporter vectors (200 ng) in the presence or absence of an HTLV-I Tax, Foxp3, ΔFKH, or control expression vector (500 ng) and internal reference plasmid (pGL4-TKhRluc2; 50 ng).
T113	2964-3047	Sentence	denotes	Cells were harvested at 24 h posttransfection and analyzed for luciferase activity.
T114	3048-3126	Sentence	denotes	Relative luciferase activity was normalized to the internal reference control.
T115	3127-3348	Sentence	denotes	(C) Expression of HTLV-I Tax in (A) and (B) was measured by quantitative RT-PCR (TaqMan) to demonstrate that Foxp3 did not suppress Tax transactivation of NF-κB and the HTLV-I LTR by down-regulating the expression of Tax.
T116	3349-3673	Sentence	denotes	(D) HEK 293T cells (5 × 105) were seeded into six-well plates 1 d prior to transfection with a Gal4 luciferase reporter vector (200 ng) in the presence or absence of a Gal4-BD or Gal4-BD-Tax expression vector (500 ng), Foxp3, ΔFKH, or control expression vector (500 ng) and internal reference plasmid (pGL4-TKhRluc2; 50 ng).
T117	3674-3757	Sentence	denotes	Cells were harvested at 24 h posttransfection and analyzed for luciferase activity.
T118	3758-3836	Sentence	denotes	Relative luciferase activity was normalized to the internal reference control.
T119	3839-4101	Sentence	denotes	To determine whether Foxp3 inhibited the transactivation functions of Tax by directly associating with this viral protein, we generated an expression vector in which HTLV-I Tax was fused in-frame to the carboxyl terminus of the Gal4 DNA-binding domain (Gal4-BD).
T120	4102-4298	Sentence	denotes	This Gal4-BD-Tax fusion protein activated transcription of a synthetic promoter containing five Gal4 binding sites, while Gal4-BD was insufficient to stimulate transcription by itself (Figure 4D).
T121	4299-4563	Sentence	denotes	Transactivation of the Gal4-resposive promoter by Gal4-BD-Tax remained relatively unaffected by overexpression of either EGFP (control), Foxp3, or ΔFKH, suggesting that Foxp3 does not repress Tax transactivation by directly interfacing with the HTLV-I Tax protein.
T122	4564-4799	Sentence	denotes	To confirm that Foxp3 had a direct effect on HTLV-I replication, we transfected HEK 293T cells with a well-characterized HTLV-I infectious molecular clone (termed ACH) [30] in the presence of full-length Foxp3, ΔFKH, or control vector.
T123	4800-4961	Sentence	denotes	ACH has been previously shown to direct the expression of viral antigens, produce infectious virus, and transform CD4+ T cells both in vitro and in vivo [31,32].
T124	4962-5088	Sentence	denotes	After 24 h, the amount of viral antigen expression, in this case Tax mRNA, was detected by a sensitive real-time RT-PCR assay.
T125	5089-5331	Sentence	denotes	As illustrated in Figure 5, the level of Tax mRNA synthesized from ACH was down-regulated in the presence of Foxp3 compared to the level produced in the presence of the control vector. ΔFKH did not have a discernable affect on Tax expression.
T126	5332-5452	Sentence	denotes	These data indicate that Foxp3 is capable of repressing the expression of Tax from an infectious HTLV-I molecular clone.
T127	5453-5550	Sentence	denotes	Figure 5 Foxp3 Inhibits the Expression of HTLV-I Tax Directed from an Infectious Molecular Clone
T128	5551-5788	Sentence	denotes	HEK 293T cells (5 × 105) were seeded into six-well plates 1 d prior to transfection in the absence or presence of an HTLV-I infectious molecular clone (pACH; 800 ng) and either a control (EGFP), Foxp3, or ΔFKH expression vector (800 ng).
T129	5789-5884	Sentence	denotes	Expression of HTLV-I Tax from the molecular clone was measured by quantitative RT-PCR (TaqMan).

2_test

Id	Subject	Object	Predicate	Lexical cue
16652169-15790681-98518412	259-261	15790681	denotes	15
16652169-7637811-98518413	520-522	7637811	denotes	24
16652169-7637812-98518413	520-522	7637812	denotes	24
16652169-8602268-98518413	520-522	8602268	denotes	24
16652169-10766811-98518413	520-522	10766811	denotes	24
16652169-11080795-98518413	520-522	11080795	denotes	24
16652169-7936632-98518413	520-522	7936632	denotes	24
16652169-11080795-98518414	661-663	11080795	denotes	28
16652169-7936632-98518415	664-666	7936632	denotes	29
16652169-15285791-98518416	824-826	15285791	denotes	18
16652169-7941334-98518417	4733-4735	7941334	denotes	30
16652169-10233947-98518418	4954-4956	10233947	denotes	31
16652169-8794375-98518419	4957-4959	8794375	denotes	32

pmc-enju-pas

Id	Subject	Object	Predicate	Lexical cue
T7542	0-3	DT	denotes	The
T7543	4-19	NNP	denotes	Transactivation
T7544	20-29	NN	denotes	Functions
T7545	30-32	IN	denotes	of
T7546	33-39	NN	denotes	HTLV-I
T7547	40-43	NN	denotes	Tax
T7548	44-47	VB	denotes	Are
T7549	48-58	VB	denotes	Suppressed
T7550	59-61	IN	denotes	by
T7551	62-67	NN	denotes	Foxp3
T7552	68-76	JJ	denotes	Previous
T7553	77-84	NN	denotes	studies
T7554	85-87	IN	denotes	by
T7555	88-96	NNP	denotes	Bettelli
T7556	97-100	CC	denotes	and
T7557	101-111	NN	denotes	colleagues
T7558	112-116	VB	denotes	have
T7559	117-129	VB	denotes	demonstrated
T7560	130-134	IN	denotes	that
T7561	135-140	NN	denotes	Foxp3
T7562	141-144	MD	denotes	can
T7563	145-152	VB	denotes	repress
T7564	153-157	CC	denotes	both
T7565	158-161	DT	denotes	the
T7566	162-167	JJ	denotes	basal
T7567	168-174	NN	denotes	levels
T7568	175-177	IN	denotes	of
T7569	178-183	NN	denotes	NF-κB
T7570	184-194	NN	denotes	activation
T7571	195-197	RB	denotes	as
T7572	198-202	RB	denotes	well
T7573	203-205	IN	denotes	as
T7574	206-211	NN	denotes	tumor
T7575	212-220	NN	denotes	necrosis
T7576	221-240	JJ	denotes	factor-α-stimulated
T7577	241-246	NN	denotes	NF-κB
T7578	247-257	NN	denotes	activation
T7579	258-259	-LRB-	denotes	[
T7580	259-261	CD	denotes	15
T7581	261-262	-RRB-	denotes	]
T7582	264-267	PRP-DOLLAR-	denotes	Our
T7583	268-272	JJ	denotes	next
T7584	273-277	NN	denotes	step
T7585	278-281	VB	denotes	was
T7586	282-284	TO	denotes	to
T7587	285-294	VB	denotes	determine
T7588	295-302	IN	denotes	whether
T7589	303-308	NN	denotes	Foxp3
T7590	309-314	MD	denotes	could
T7591	315-319	RB	denotes	also
T7592	320-328	VB	denotes	suppress
T7593	329-332	DT	denotes	the
T7594	333-343	NN	denotes	activation
T7595	344-346	IN	denotes	of
T7596	347-352	NN	denotes	NF-κB
T7597	353-359	VB	denotes	caused
T7598	360-362	IN	denotes	by
T7599	363-364	DT	denotes	a
T7600	365-371	JJ	denotes	strong
T7601	372-377	JJ	denotes	viral
T7602	378-392	NN	denotes	transactivator
T7603	393-400	NN	denotes	protein
T7604	402-408	NN	denotes	HTLV-I
T7605	409-416	VB	denotes	encodes
T7606	417-418	DT	denotes	a
T7607	419-434	JJ	denotes	multifunctional
T7608	435-449	NN	denotes	transactivator
T7609	450-457	NN	denotes	protein
T7610	457-458	-COMMA-	denotes	,
T7611	459-462	NN	denotes	Tax
T7612	462-463	-COMMA-	denotes	,
T7613	464-471	JJ	denotes	capable
T7614	472-474	IN	denotes	of
T7615	475-485	VB	denotes	activating
T7616	486-490	CC	denotes	both
T7617	491-494	DT	denotes	the
T7618	495-500	NN	denotes	NF-κB
T7619	501-504	CC	denotes	and
T7620	505-509	NN	denotes	CREB
T7621	510-518	NN	denotes	pathways
T7622	519-520	-LRB-	denotes	[
T7623	520-525	CD	denotes	24–29
T7624	525-526	-RRB-	denotes	]
T7625	528-533	IN	denotes	Since
T7626	534-537	DT	denotes	the
T7627	538-544	NN	denotes	HTLV-I
T7628	545-548	NN	denotes	Tax
T7629	549-556	NN	denotes	protein
T7630	557-560	MD	denotes	can
T7631	561-569	VB	denotes	function
T7632	570-572	IN	denotes	at
T7633	573-581	JJ	denotes	multiple
T7634	582-588	NN	denotes	levels
T7635	589-591	IN	denotes	in
T7636	592-596	CC	denotes	both
T7637	597-600	DT	denotes	the
T7638	601-610	NN	denotes	cytoplasm
T7639	611-614	CC	denotes	and
T7640	615-618	DT	denotes	the
T7641	619-626	NN	denotes	nucleus
T7642	627-629	TO	denotes	to
T7643	630-639	VB	denotes	stimulate
T7644	640-650	NN	denotes	activation
T7645	651-653	IN	denotes	of
T7646	654-659	NN	denotes	NF-κB
T7647	660-661	-LRB-	denotes	[
T7648	661-666	CD	denotes	28,29
T7649	666-667	-RRB-	denotes	]
T7650	667-668	-COMMA-	denotes	,
T7651	669-671	PRP	denotes	we
T7652	672-684	VB	denotes	hypothesized
T7653	685-689	IN	denotes	that
T7654	690-704	NN	denotes	overexpression
T7655	705-707	IN	denotes	of
T7656	708-713	NN	denotes	Foxp3
T7657	714-717	MD	denotes	may
T7658	718-727	VB	denotes	interfere
T7659	728-732	IN	denotes	with
T7660	733-737	DT	denotes	this
T7661	738-745	NN	denotes	process
T7662	747-754	RB	denotes	However
T7663	754-755	-COMMA-	denotes	,
T7664	756-761	IN	denotes	since
T7665	762-775	JJ	denotes	Tax-dependent
T7666	776-782	NN	denotes	HTLV-I
T7667	783-787	NN	denotes	gene
T7668	788-798	NN	denotes	expression
T7669	799-801	VB	denotes	is
T7670	802-813	JJ	denotes	independent
T7671	814-816	IN	denotes	of
T7672	817-822	NN	denotes	NF-κB
T7673	823-824	-LRB-	denotes	[
T7674	824-826	CD	denotes	18
T7675	826-827	-RRB-	denotes	]
T7676	827-828	-COMMA-	denotes	,
T7677	829-831	PRP	denotes	we
T7678	832-836	RB	denotes	also
T7679	837-849	VB	denotes	hypothesized
T7680	850-854	IN	denotes	that
T7681	855-860	NN	denotes	Foxp3
T7682	861-866	MD	denotes	would
T7683	867-870	RB	denotes	not
T7684	871-877	VB	denotes	affect
T7685	878-891	JJ	denotes	Tax-dependent
T7686	892-902	NN	denotes	activation
T7687	903-905	IN	denotes	of
T7688	906-909	DT	denotes	the
T7689	910-916	NN	denotes	HTLV-I
T7690	917-920	NN	denotes	LTR
T7691	922-924	TO	denotes	To
T7692	925-929	VB	denotes	test
T7693	930-935	DT	denotes	these
T7694	936-946	NN	denotes	hypotheses
T7695	946-947	-COMMA-	denotes	,
T7696	948-950	PRP	denotes	we
T7697	951-964	VB	denotes	overexpressed
T7698	965-971	NN	denotes	HTLV-I
T7699	972-975	NN	denotes	Tax
T7700	975-976	-COMMA-	denotes	,
T7701	977-988	JJ	denotes	full-length
T7702	989-994	NN	denotes	Foxp3
T7703	994-995	-COMMA-	denotes	,
T7704	996-1002	CC	denotes	and/or
T7705	1003-1007	NN	denotes	ΔFKH
T7706	1008-1010	IN	denotes	in
T7707	1011-1014	NN	denotes	HEK
T7708	1015-1019	NN	denotes	293T
T7709	1020-1025	NN	denotes	cells
T7710	1026-1039	VB	denotes	cotransfected
T7711	1040-1044	IN	denotes	with
T7712	1045-1047	DT	denotes	an
T7713	1048-1054	NN	denotes	HTLV-I
T7714	1055-1058	NN	denotes	LTR
T7715	1059-1061	CC	denotes	or
T7716	1062-1067	NN	denotes	NF-κB
T7717	1068-1076	NN	denotes	reporter
T7718	1077-1083	NN	denotes	vector
T7719	1085-1087	IN	denotes	As
T7720	1088-1093	VB	denotes	shown
T7721	1094-1096	IN	denotes	in
T7722	1097-1103	NN	denotes	Figure
T7723	1104-1106	NN	denotes	4A
T7724	1106-1107	-COMMA-	denotes	,
T7725	1108-1114	NN	denotes	HTLV-I
T7726	1115-1118	NN	denotes	Tax
T7727	1119-1127	RB	denotes	strongly
T7728	1128-1140	VB	denotes	up-regulated
T7729	1141-1156	JJ	denotes	NF-κB-dependent
T7730	1157-1172	JJ	denotes	transcriptional
T7731	1173-1183	NN	denotes	activation
T7732	1184-1185	-LRB-	denotes	(
T7733	1185-1193	JJ	denotes	~60-fold
T7734	1193-1194	-RRB-	denotes	)
T7735	1196-1209	RB	denotes	Interestingly
T7736	1209-1210	-COMMA-	denotes	,
T7737	1211-1225	NN	denotes	overexpression
T7738	1226-1228	IN	denotes	of
T7739	1229-1234	NN	denotes	Foxp3
T7740	1234-1235	-COMMA-	denotes	,
T7741	1236-1239	CC	denotes	but
T7742	1240-1243	RB	denotes	not
T7743	1244-1248	NN	denotes	ΔFKH
T7744	1248-1249	-COMMA-	denotes	,
T7745	1250-1260	VB	denotes	suppressed
T7746	1261-1273	JJ	denotes	Tax-mediated
T7747	1274-1284	NN	denotes	activation
T7748	1285-1287	IN	denotes	of
T7749	1288-1303	JJ	denotes	NF-κB-dependent
T7750	1304-1317	NN	denotes	transcription
T7751	1319-1324	DT	denotes	These
T7752	1325-1337	NN	denotes	observations
T7753	1338-1345	RB	denotes	further
T7754	1346-1353	VB	denotes	suggest
T7755	1354-1358	IN	denotes	that
T7756	1359-1362	DT	denotes	the
T7757	1363-1380	JJ	denotes	carboxyl-terminal
T7758	1381-1384	NN	denotes	FKH
T7759	1385-1391	NN	denotes	domain
T7760	1392-1394	VB	denotes	is
T7761	1395-1403	VB	denotes	required
T7762	1404-1407	IN	denotes	for
T7763	1408-1418	VB	denotes	inhibiting
T7764	1419-1429	NN	denotes	activation
T7765	1430-1432	IN	denotes	of
T7766	1433-1438	NN	denotes	NF-κB
T7767	1439-1441	IN	denotes	in
T7768	1442-1445	DT	denotes	the
T7769	1446-1454	NN	denotes	presence
T7770	1455-1457	IN	denotes	of
T7771	1458-1461	NN	denotes	Tax
T7772	1462-1464	IN	denotes	in
T7773	1465-1468	NN	denotes	HEK
T7774	1469-1473	NN	denotes	293T
T7775	1474-1479	NN	denotes	cells
T7776	1479-1480	-COMMA-	denotes	,
T7777	1481-1491	RB	denotes	strikingly
T7778	1492-1499	JJ	denotes	similar
T7779	1500-1502	TO	denotes	to
T7780	1503-1506	DT	denotes	the
T7781	1507-1519	NN	denotes	requirements
T7782	1520-1522	IN	denotes	of
T7783	1523-1528	NN	denotes	Foxp3
T7784	1529-1539	NN	denotes	inhibition
T7785	1540-1542	IN	denotes	of
T7786	1543-1548	JJ	denotes	basal
T7787	1549-1554	NN	denotes	NF-κB
T7788	1555-1565	NN	denotes	activation
T7789	1566-1571	VB	denotes	shown
T7790	1572-1574	IN	denotes	in
T7791	1575-1581	NN	denotes	Figure
T7792	1582-1584	NN	denotes	2B
T7793	1586-1601	NN	denotes	Transactivation
T7794	1602-1604	IN	denotes	of
T7795	1605-1608	DT	denotes	the
T7796	1609-1615	NN	denotes	HTLV-I
T7797	1616-1619	NN	denotes	LTR
T7798	1620-1623	VB	denotes	was
T7799	1624-1634	VB	denotes	stimulated
T7800	1635-1640	IN	denotes	about
T7801	1641-1648	RB	denotes	55-fold
T7802	1649-1651	IN	denotes	by
T7803	1652-1666	NN	denotes	overexpression
T7804	1667-1669	IN	denotes	of
T7805	1670-1673	NN	denotes	Tax
T7806	1674-1675	-LRB-	denotes	(
T7807	1675-1681	NN	denotes	Figure
T7808	1682-1684	NN	denotes	4B
T7809	1684-1685	-RRB-	denotes	)
T7810	1685-1686	-COMMA-	denotes	,
T7811	1687-1692	IN	denotes	while
T7812	1693-1705	NN	denotes	transfection
T7813	1706-1708	IN	denotes	of
T7814	1709-1714	NN	denotes	Foxp3
T7815	1715-1725	VB	denotes	suppressed
T7816	1726-1739	JJ	denotes	Tax-dependent
T7817	1740-1746	NN	denotes	HTLV-I
T7818	1747-1750	NN	denotes	LTR
T7819	1751-1761	NN	denotes	activation
T7820	1761-1762	-COMMA-	denotes	,
T7821	1763-1771	IN	denotes	although
T7822	1772-1778	NN	denotes	HTLV-I
T7823	1779-1782	NN	denotes	LTR
T7824	1783-1793	NN	denotes	activation
T7825	1794-1796	IN	denotes	in
T7826	1797-1800	DT	denotes	the
T7827	1801-1809	NN	denotes	presence
T7828	1810-1812	CC	denotes	or
T7829	1813-1820	NN	denotes	absence
T7830	1821-1823	IN	denotes	of
T7831	1824-1827	NN	denotes	Tax
T7832	1828-1830	VB	denotes	is
T7833	1831-1842	JJ	denotes	independent
T7834	1843-1845	IN	denotes	of
T7835	1846-1851	NN	denotes	NF-κB
T7836	1852-1854	CC	denotes	or
T7837	1855-1860	NN	denotes	NF-AT
T7838	1861-1862	-LRB-	denotes	(
T7839	1862-1869	DT	denotes	another
T7840	1870-1885	JJ	denotes	transcriptional
T7841	1886-1895	NN	denotes	activator
T7842	1896-1901	VB	denotes	known
T7843	1902-1904	TO	denotes	to
T7844	1905-1913	VB	denotes	interact
T7845	1914-1918	IN	denotes	with
T7846	1919-1924	NN	denotes	Foxp3
T7847	1924-1925	-RRB-	denotes	)
T7848	1927-1938	RB	denotes	Furthermore
T7849	1938-1939	-COMMA-	denotes	,
T7850	1940-1954	NN	denotes	overexpression
T7851	1955-1957	IN	denotes	of
T7852	1958-1962	NN	denotes	ΔFKH
T7853	1963-1967	RB	denotes	also
T7854	1968-1971	VB	denotes	led
T7855	1972-1974	TO	denotes	to
T7856	1975-1986	NN	denotes	suppression
T7857	1987-1989	IN	denotes	of
T7858	1990-1996	NN	denotes	HTLV-I
T7859	1997-2012	NN	denotes	transactivation
T7860	2013-2015	IN	denotes	by
T7861	2016-2019	NN	denotes	Tax
T7862	2020-2022	TO	denotes	to
T7863	2023-2024	DT	denotes	a
T7864	2025-2032	JJ	denotes	similar
T7865	2033-2039	NN	denotes	extent
T7866	2040-2042	IN	denotes	as
T7867	2043-2054	JJ	denotes	full-length
T7868	2055-2060	NN	denotes	Foxp3
T7869	2061-2062	-LRB-	denotes	(
T7870	2062-2068	NN	denotes	Figure
T7871	2069-2071	NN	denotes	4B
T7872	2071-2072	-RRB-	denotes	)
T7873	2074-2077	DT	denotes	The
T7874	2078-2089	JJ	denotes	suppressive
T7875	2090-2097	NN	denotes	effects
T7876	2098-2103	VB	denotes	shown
T7877	2104-2106	IN	denotes	in
T7878	2107-2113	NN	denotes	Figure
T7879	2114-2116	NN	denotes	4A
T7880	2117-2120	CC	denotes	and
T7881	2121-2123	NN	denotes	4B
T7882	2124-2128	VB	denotes	were
T7883	2129-2132	RB	denotes	not
T7884	2133-2136	DT	denotes	the
T7885	2137-2143	NN	denotes	result
T7886	2144-2146	IN	denotes	of
T7887	2147-2152	NN	denotes	Foxp3
T7888	2153-2168	VB	denotes	down-regulating
T7889	2169-2172	DT	denotes	the
T7890	2173-2183	NN	denotes	expression
T7891	2184-2186	IN	denotes	of
T7892	2187-2190	DT	denotes	the
T7893	2191-2202	VB	denotes	transfected
T7894	2203-2206	NN	denotes	Tax
T7895	2207-2214	NN	denotes	plasmid
T7896	2215-2217	IN	denotes	as
T7897	2218-2228	VB	denotes	determined
T7898	2229-2231	IN	denotes	by
T7899	2232-2241	JJ	denotes	real-time
T7900	2242-2248	NN	denotes	RT-PCR
T7901	2249-2250	-LRB-	denotes	(
T7902	2250-2256	NN	denotes	Figure
T7903	2257-2259	NN	denotes	4C
T7904	2259-2260	-RRB-	denotes	)
T7905	2262-2267	DT	denotes	These
T7906	2268-2275	NN	denotes	results
T7907	2276-2284	RB	denotes	strongly
T7908	2285-2292	VB	denotes	suggest
T7909	2293-2297	IN	denotes	that
T7910	2298-2303	NN	denotes	Foxp3
T7911	2304-2313	VB	denotes	interacts
T7912	2314-2318	IN	denotes	with
T7913	2319-2334	JJ	denotes	transcriptional
T7914	2335-2345	NN	denotes	regulators
T7915	2346-2348	IN	denotes	in
T7916	2349-2357	NN	denotes	addition
T7917	2358-2360	TO	denotes	to
T7918	2361-2366	NN	denotes	NF-κB
T7919	2367-2370	CC	denotes	and
T7920	2371-2376	NN	denotes	NF-AT
T7921	2376-2377	-COMMA-	denotes	,
T7922	2378-2381	CC	denotes	and
T7923	2382-2386	IN	denotes	that
T7924	2387-2390	DT	denotes	the
T7925	2391-2408	JJ	denotes	carboxyl-terminal
T7926	2409-2412	NN	denotes	FKH
T7927	2413-2419	NN	denotes	domain
T7928	2419-2420	-COMMA-	denotes	,
T7929	2421-2424	CC	denotes	and
T7930	2425-2434	RB	denotes	therefore
T7931	2435-2447	NN	denotes	localization
T7932	2448-2450	TO	denotes	to
T7933	2451-2454	DT	denotes	the
T7934	2455-2462	NN	denotes	nucleus
T7935	2462-2463	-COMMA-	denotes	,
T7936	2464-2467	VB	denotes	are
T7937	2468-2471	RB	denotes	not
T7938	2472-2480	VB	denotes	required
T7939	2481-2484	IN	denotes	for
T7940	2485-2495	NN	denotes	inhibition
T7941	2496-2498	IN	denotes	of
T7942	2499-2511	JJ	denotes	Tax-mediated
T7943	2512-2518	NN	denotes	HTLV-I
T7944	2519-2522	NN	denotes	LTR
T7945	2523-2533	NN	denotes	activation
T7946	2534-2535	-LRB-	denotes	(
T7947	2535-2539	RB	denotes	even
T7948	2540-2542	IN	denotes	in
T7949	2543-2546	NN	denotes	HEK
T7950	2547-2551	NN	denotes	293T
T7951	2552-2557	NN	denotes	cells
T7952	2557-2558	-RRB-	denotes	)
T7953	3839-3841	TO	denotes	To
T7954	3842-3851	VB	denotes	determine
T7955	3852-3859	IN	denotes	whether
T7956	3860-3865	NN	denotes	Foxp3
T7957	3866-3875	VB	denotes	inhibited
T7958	3876-3879	DT	denotes	the
T7959	3880-3895	NN	denotes	transactivation
T7960	3896-3905	NN	denotes	functions
T7961	3906-3908	IN	denotes	of
T7962	3909-3912	NN	denotes	Tax
T7963	3913-3915	IN	denotes	by
T7964	3916-3924	RB	denotes	directly
T7965	3925-3936	VB	denotes	associating
T7966	3937-3941	IN	denotes	with
T7967	3942-3946	DT	denotes	this
T7968	3947-3952	JJ	denotes	viral
T7969	3953-3960	NN	denotes	protein
T7970	3960-3961	-COMMA-	denotes	,
T7971	3962-3964	PRP	denotes	we
T7972	3965-3974	VB	denotes	generated
T7973	3975-3977	DT	denotes	an
T7974	3978-3988	NN	denotes	expression
T7975	3989-3995	NN	denotes	vector
T7976	3996-3998	IN	denotes	in
T7977	3999-4004	WDT	denotes	which
T7978	4005-4011	NN	denotes	HTLV-I
T7979	4012-4015	NN	denotes	Tax
T7980	4016-4019	VB	denotes	was
T7981	4020-4025	VB	denotes	fused
T7982	4026-4034	JJ	denotes	in-frame
T7983	4035-4037	TO	denotes	to
T7984	4038-4041	DT	denotes	the
T7985	4042-4050	NN	denotes	carboxyl
T7986	4051-4059	NN	denotes	terminus
T7987	4060-4062	IN	denotes	of
T7988	4063-4066	DT	denotes	the
T7989	4067-4071	NN	denotes	Gal4
T7990	4072-4083	JJ	denotes	DNA-binding
T7991	4084-4090	NN	denotes	domain
T7992	4091-4092	-LRB-	denotes	(
T7993	4092-4099	NN	denotes	Gal4-BD
T7994	4099-4100	-RRB-	denotes	)
T7995	4102-4106	DT	denotes	This
T7996	4107-4118	NN	denotes	Gal4-BD-Tax
T7997	4119-4125	NN	denotes	fusion
T7998	4126-4133	NN	denotes	protein
T7999	4134-4143	VB	denotes	activated
T8000	4144-4157	NN	denotes	transcription
T8001	4158-4160	IN	denotes	of
T8002	4161-4162	DT	denotes	a
T8003	4163-4172	JJ	denotes	synthetic
T8004	4173-4181	NN	denotes	promoter
T8005	4182-4192	VB	denotes	containing
T8006	4193-4197	CD	denotes	five
T8007	4198-4202	NN	denotes	Gal4
T8008	4203-4210	NN	denotes	binding
T8009	4211-4216	NN	denotes	sites
T8010	4216-4217	-COMMA-	denotes	,
T8011	4218-4223	IN	denotes	while
T8012	4224-4231	NN	denotes	Gal4-BD
T8013	4232-4235	VB	denotes	was
T8014	4236-4248	JJ	denotes	insufficient
T8015	4249-4251	TO	denotes	to
T8016	4252-4261	VB	denotes	stimulate
T8017	4262-4275	NN	denotes	transcription
T8018	4276-4278	IN	denotes	by
T8019	4279-4285	PRP	denotes	itself
T8020	4286-4287	-LRB-	denotes	(
T8021	4287-4293	NN	denotes	Figure
T8022	4294-4296	NN	denotes	4D
T8023	4296-4297	-RRB-	denotes	)
T8024	4299-4314	NN	denotes	Transactivation
T8025	4315-4317	IN	denotes	of
T8026	4318-4321	DT	denotes	the
T8027	4322-4336	JJ	denotes	Gal4-resposive
T8028	4337-4345	NN	denotes	promoter
T8029	4346-4348	IN	denotes	by
T8030	4349-4360	NN	denotes	Gal4-BD-Tax
T8031	4361-4369	VB	denotes	remained
T8032	4370-4380	RB	denotes	relatively
T8033	4381-4391	JJ	denotes	unaffected
T8034	4392-4394	IN	denotes	by
T8035	4395-4409	NN	denotes	overexpression
T8036	4410-4412	IN	denotes	of
T8037	4413-4419	CC	denotes	either
T8038	4420-4424	NN	denotes	EGFP
T8039	4425-4426	-LRB-	denotes	(
T8040	4426-4433	NN	denotes	control
T8041	4433-4434	-RRB-	denotes	)
T8042	4434-4435	-COMMA-	denotes	,
T8043	4436-4441	NN	denotes	Foxp3
T8044	4441-4442	-COMMA-	denotes	,
T8045	4443-4445	CC	denotes	or
T8046	4446-4450	NN	denotes	ΔFKH
T8047	4450-4451	-COMMA-	denotes	,
T8048	4452-4462	VB	denotes	suggesting
T8049	4463-4467	IN	denotes	that
T8050	4468-4473	NN	denotes	Foxp3
T8051	4474-4478	VB	denotes	does
T8052	4479-4482	RB	denotes	not
T8053	4483-4490	VB	denotes	repress
T8054	4491-4494	NN	denotes	Tax
T8055	4495-4510	NN	denotes	transactivation
T8056	4511-4513	IN	denotes	by
T8057	4514-4522	RB	denotes	directly
T8058	4523-4534	VB	denotes	interfacing
T8059	4535-4539	IN	denotes	with
T8060	4540-4543	DT	denotes	the
T8061	4544-4550	NN	denotes	HTLV-I
T8062	4551-4554	NN	denotes	Tax
T8063	4555-4562	NN	denotes	protein
T8064	4564-4566	TO	denotes	To
T8065	4567-4574	VB	denotes	confirm
T8066	4575-4579	IN	denotes	that
T8067	4580-4585	NN	denotes	Foxp3
T8068	4586-4589	VB	denotes	had
T8069	4590-4591	DT	denotes	a
T8070	4592-4598	JJ	denotes	direct
T8071	4599-4605	NN	denotes	effect
T8072	4606-4608	IN	denotes	on
T8073	4609-4615	NN	denotes	HTLV-I
T8074	4616-4627	NN	denotes	replication
T8075	4627-4628	-COMMA-	denotes	,
T8076	4629-4631	PRP	denotes	we
T8077	4632-4643	VB	denotes	transfected
T8078	4644-4647	NN	denotes	HEK
T8079	4648-4652	NN	denotes	293T
T8080	4653-4658	NN	denotes	cells
T8081	4659-4663	IN	denotes	with
T8082	4664-4665	DT	denotes	a
T8083	4666-4684	JJ	denotes	well-characterized
T8084	4685-4691	NN	denotes	HTLV-I
T8085	4692-4702	JJ	denotes	infectious
T8086	4703-4712	JJ	denotes	molecular
T8087	4713-4718	NN	denotes	clone
T8088	4719-4720	-LRB-	denotes	(
T8089	4720-4726	VB	denotes	termed
T8090	4727-4730	NN	denotes	ACH
T8091	4730-4731	-RRB-	denotes	)
T8092	4732-4733	-LRB-	denotes	[
T8093	4733-4735	CD	denotes	30
T8094	4735-4736	-RRB-	denotes	]
T8095	4737-4739	IN	denotes	in
T8096	4740-4743	DT	denotes	the
T8097	4744-4752	NN	denotes	presence
T8098	4753-4755	IN	denotes	of
T8099	4756-4767	JJ	denotes	full-length
T8100	4768-4773	NN	denotes	Foxp3
T8101	4773-4774	-COMMA-	denotes	,
T8102	4775-4779	NN	denotes	ΔFKH
T8103	4779-4780	-COMMA-	denotes	,
T8104	4781-4783	CC	denotes	or
T8105	4784-4791	NN	denotes	control
T8106	4792-4798	NN	denotes	vector
T8107	4800-4803	NN	denotes	ACH
T8108	4804-4807	VB	denotes	has
T8109	4808-4812	VB	denotes	been
T8110	4813-4823	RB	denotes	previously
T8111	4824-4829	VB	denotes	shown
T8112	4830-4832	TO	denotes	to
T8113	4833-4839	VB	denotes	direct
T8114	4840-4843	DT	denotes	the
T8115	4844-4854	NN	denotes	expression
T8116	4855-4857	IN	denotes	of
T8117	4858-4863	JJ	denotes	viral
T8118	4864-4872	NN	denotes	antigens
T8119	4872-4873	-COMMA-	denotes	,
T8120	4874-4881	VB	denotes	produce
T8121	4882-4892	JJ	denotes	infectious
T8122	4893-4898	NN	denotes	virus
T8123	4898-4899	-COMMA-	denotes	,
T8124	4900-4903	CC	denotes	and
T8125	4904-4913	VB	denotes	transform
T8126	4914-4918	JJ	denotes	CD4+
T8127	4919-4920	NN	denotes	T
T8128	4921-4926	NN	denotes	cells
T8129	4927-4931	CC	denotes	both
T8130	4932-4934	FW	denotes	in
T8131	4935-4940	FW	denotes	vitro
T8132	4941-4944	CC	denotes	and
T8133	4945-4947	FW	denotes	in
T8134	4948-4952	FW	denotes	vivo
T8135	4953-4954	-LRB-	denotes	[
T8136	4954-4959	CD	denotes	31,32
T8137	4959-4960	-RRB-	denotes	]
T8138	4962-4967	IN	denotes	After
T8139	4968-4970	CD	denotes	24
T8140	4971-4972	NN	denotes	h
T8141	4972-4973	-COMMA-	denotes	,
T8142	4974-4977	DT	denotes	the
T8143	4978-4984	NN	denotes	amount
T8144	4985-4987	IN	denotes	of
T8145	4988-4993	JJ	denotes	viral
T8146	4994-5001	NN	denotes	antigen
T8147	5002-5012	NN	denotes	expression
T8148	5012-5013	-COMMA-	denotes	,
T8149	5014-5016	IN	denotes	in
T8150	5017-5021	DT	denotes	this
T8151	5022-5026	NN	denotes	case
T8152	5027-5030	NN	denotes	Tax
T8153	5031-5035	NN	denotes	mRNA
T8154	5035-5036	-COMMA-	denotes	,
T8155	5037-5040	VB	denotes	was
T8156	5041-5049	VB	denotes	detected
T8157	5050-5052	IN	denotes	by
T8158	5053-5054	DT	denotes	a
T8159	5055-5064	JJ	denotes	sensitive
T8160	5065-5074	JJ	denotes	real-time
T8161	5075-5081	NN	denotes	RT-PCR
T8162	5082-5087	NN	denotes	assay
T8163	5089-5091	IN	denotes	As
T8164	5092-5103	VB	denotes	illustrated
T8165	5104-5106	IN	denotes	in
T8166	5107-5113	NN	denotes	Figure
T8167	5114-5115	CD	denotes	5
T8168	5115-5116	-COMMA-	denotes	,
T8169	5117-5120	DT	denotes	the
T8170	5121-5126	NN	denotes	level
T8171	5127-5129	IN	denotes	of
T8172	5130-5133	NN	denotes	Tax
T8173	5134-5138	NN	denotes	mRNA
T8174	5139-5150	VB	denotes	synthesized
T8175	5151-5155	IN	denotes	from
T8176	5156-5159	NN	denotes	ACH
T8177	5160-5163	VB	denotes	was
T8178	5164-5178	VB	denotes	down-regulated
T8179	5179-5181	IN	denotes	in
T8180	5182-5185	DT	denotes	the
T8181	5186-5194	NN	denotes	presence
T8182	5195-5197	IN	denotes	of
T8183	5198-5203	NN	denotes	Foxp3
T8184	5204-5212	VB	denotes	compared
T8185	5213-5215	TO	denotes	to
T8186	5216-5219	DT	denotes	the
T8187	5220-5225	NN	denotes	level
T8188	5226-5234	VB	denotes	produced
T8189	5235-5237	IN	denotes	in
T8190	5238-5241	DT	denotes	the
T8191	5242-5250	NN	denotes	presence
T8192	5251-5253	IN	denotes	of
T8193	5254-5257	DT	denotes	the
T8194	5258-5265	NN	denotes	control
T8195	5266-5273	NN	denotes	vector.
T8196	5274-5278	NN	denotes	ΔFKH
T8197	5279-5282	VB	denotes	did
T8198	5283-5286	RB	denotes	not
T8199	5287-5291	VB	denotes	have
T8200	5292-5293	DT	denotes	a
T8201	5294-5305	JJ	denotes	discernable
T8202	5306-5312	NN	denotes	affect
T8203	5313-5315	IN	denotes	on
T8204	5316-5319	NN	denotes	Tax
T8205	5320-5330	NN	denotes	expression
T8206	5332-5337	DT	denotes	These
T8207	5338-5342	NN	denotes	data
T8208	5343-5351	VB	denotes	indicate
T8209	5352-5356	IN	denotes	that
T8210	5357-5362	NN	denotes	Foxp3
T8211	5363-5365	VB	denotes	is
T8212	5366-5373	JJ	denotes	capable
T8213	5374-5376	IN	denotes	of
T8214	5377-5387	VB	denotes	repressing
T8215	5388-5391	DT	denotes	the
T8216	5392-5402	NN	denotes	expression
T8217	5403-5405	IN	denotes	of
T8218	5406-5409	NN	denotes	Tax
T8219	5410-5414	IN	denotes	from
T8220	5415-5417	DT	denotes	an
T8221	5418-5428	JJ	denotes	infectious
T8222	5429-5435	NN	denotes	HTLV-I
T8223	5436-5445	JJ	denotes	molecular
T8224	5446-5451	NN	denotes	clone
R5890	T7544	T7542	arg1Of	Functions,The
R5891	T7544	T7543	arg1Of	Functions,Transactivation
R5892	T7544	T7545	arg1Of	Functions,of
R5898	T7553	T7552	arg1Of	studies,Previous
R5899	T7553	T7554	arg1Of	studies,by
R5900	T7553	T7558	arg1Of	studies,have
R5901	T7553	T7559	arg1Of	studies,demonstrated
R5902	T7555	T7556	arg1Of	Bettelli,and
R5903	T7556	T7554	arg2Of	and,by
R5904	T7557	T7556	arg2Of	colleagues,and
R5905	T7559	T7558	arg2Of	demonstrated,have
R5906	T7561	T7562	arg1Of	Foxp3,can
R5907	T7561	T7563	arg1Of	Foxp3,repress
R5908	T7563	T7559	arg2Of	repress,demonstrated
R5909	T7563	T7560	arg1Of	repress,that
R5910	T7563	T7562	arg2Of	repress,can
R5911	T7563	T7579	arg1Of	repress,[
R5912	T7567	T7566	arg1Of	levels,basal
R5913	T7567	T7568	arg1Of	levels,of
R5914	T7567	T7573	arg1Of	levels,as
R5915	T7570	T7568	arg2Of	activation,of
R5916	T7570	T7569	arg1Of	activation,NF-κB
R5917	T7573	T7563	arg2Of	as,repress
R5918	T7573	T7564	arg1Of	as,both
R5919	T7573	T7565	arg1Of	as,the
R5920	T7573	T7571	arg1Of	as,as
R5921	T7573	T7572	arg1Of	as,well
R5922	T7576	T7574	arg1Of	factor-α-stimulated,tumor
R5923	T7576	T7575	arg1Of	factor-α-stimulated,necrosis
R5924	T7578	T7573	arg2Of	activation,as
R5925	T7578	T7576	arg1Of	activation,factor-α-stimulated
R5926	T7578	T7577	arg1Of	activation,NF-κB
R5927	T7580	T7579	arg2Of	15,[
R5928	T7581	T7579	arg3Of	],[
R5929	T7584	T7582	arg1Of	step,Our
R5930	T7584	T7583	arg1Of	step,next
R5931	T7584	T7585	arg1Of	step,was
R5932	T7587	T7585	arg2Of	determine,was
R5933	T7587	T7586	arg1Of	determine,to
R5934	T7589	T7590	arg1Of	Foxp3,could
R5935	T7589	T7592	arg1Of	Foxp3,suppress
R5936	T7592	T7587	arg2Of	suppress,determine
R5937	T7592	T7588	arg1Of	suppress,whether
R5938	T7592	T7590	arg2Of	suppress,could
R5939	T7592	T7591	arg1Of	suppress,also
R5940	T7594	T7592	arg2Of	activation,suppress
R5941	T7594	T7593	arg1Of	activation,the
R5942	T7594	T7595	arg1Of	activation,of
R5943	T7596	T7595	arg2Of	NF-κB,of
R5944	T7596	T7597	arg2Of	NF-κB,caused
R5945	T7603	T7597	arg1Of	protein,caused
R5946	T7603	T7598	arg2Of	protein,by
R5947	T7603	T7599	arg1Of	protein,a
R5948	T7603	T7600	arg1Of	protein,strong
R5949	T7603	T7601	arg1Of	protein,viral
R5950	T7603	T7602	arg1Of	protein,transactivator
R5951	T7604	T7605	arg1Of	HTLV-I,encodes
R5952	T7609	T7605	arg2Of	protein,encodes
R5953	T7609	T7606	arg1Of	protein,a
R5954	T7609	T7607	arg1Of	protein,multifunctional
R5955	T7609	T7608	arg1Of	protein,transactivator
R5956	T7609	T7610	arg1Of	protein,","
R5957	T7609	T7612	arg1Of	protein,","
R5958	T7609	T7613	arg1Of	protein,capable
R5959	T7611	T7610	arg2Of	Tax,","
R5960	T7613	T7614	arg1Of	capable,of
R5961	T7615	T7614	arg2Of	activating,of
R5962	T7618	T7619	arg1Of	NF-κB,and
R5963	T7620	T7619	arg2Of	CREB,and
R5964	T7621	T7615	arg2Of	pathways,activating
R5965	T7621	T7616	arg1Of	pathways,both
R5966	T7621	T7617	arg1Of	pathways,the
R5967	T7621	T7618	arg1Of	pathways,NF-κB
R5968	T7621	T7620	arg1Of	pathways,CREB
R5969	T7621	T7622	arg1Of	pathways,[
R5970	T7623	T7622	arg2Of	24–29,[
R5971	T7624	T7622	arg3Of	],[
R5972	T7629	T7626	arg1Of	protein,the
R5973	T7629	T7627	arg1Of	protein,HTLV-I
R5974	T7629	T7628	arg1Of	protein,Tax
R5975	T7629	T7630	arg1Of	protein,can
R5976	T7629	T7631	arg1Of	protein,function
R5977	T7631	T7625	arg2Of	function,Since
R5978	T7631	T7630	arg2Of	function,can
R5979	T7631	T7632	arg1Of	function,at
R5980	T7631	T7635	arg1Of	function,in
R5981	T7631	T7642	modOf	function,to
R5982	T7634	T7632	arg2Of	levels,at
R5983	T7634	T7633	arg1Of	levels,multiple
R5984	T7638	T7637	arg1Of	cytoplasm,the
R5985	T7638	T7639	arg1Of	cytoplasm,and
R5986	T7639	T7635	arg2Of	and,in
R5987	T7639	T7636	arg1Of	and,both
R5988	T7641	T7639	arg2Of	nucleus,and
R5989	T7641	T7640	arg1Of	nucleus,the
R5990	T7643	T7642	arg1Of	stimulate,to
R5991	T7643	T7647	arg1Of	stimulate,[
R5992	T7644	T7643	arg2Of	activation,stimulate
R5993	T7644	T7645	arg1Of	activation,of
R5994	T7646	T7645	arg2Of	NF-κB,of
R5995	T7648	T7647	arg2Of	"28,29",[
R5996	T7649	T7647	arg3Of	],[
R5997	T7651	T7652	arg1Of	we,hypothesized
R5998	T7652	T7625	arg1Of	hypothesized,Since
R5999	T7652	T7650	arg1Of	hypothesized,","
R6000	T7654	T7655	arg1Of	overexpression,of
R6001	T7654	T7657	arg1Of	overexpression,may
R6002	T7654	T7658	arg1Of	overexpression,interfere
R6003	T7656	T7655	arg2Of	Foxp3,of
R6004	T7658	T7652	arg2Of	interfere,hypothesized
R6005	T7658	T7653	arg1Of	interfere,that
R6006	T7658	T7657	arg2Of	interfere,may
R6007	T7658	T7659	arg1Of	interfere,with
R6008	T7661	T7659	arg2Of	process,with
R6009	T7661	T7660	arg1Of	process,this
R6010	T7668	T7665	arg1Of	expression,Tax-dependent
R6011	T7668	T7666	arg1Of	expression,HTLV-I
R6012	T7668	T7667	arg1Of	expression,gene
R6013	T7668	T7669	arg1Of	expression,is
R6014	T7668	T7670	arg1Of	expression,independent
R6015	T7669	T7664	arg2Of	is,since
R6016	T7669	T7673	arg1Of	is,[
R6017	T7670	T7669	arg2Of	independent,is
R6018	T7670	T7671	arg1Of	independent,of
R6019	T7672	T7671	arg2Of	NF-κB,of
R6020	T7674	T7673	arg2Of	18,[
R6021	T7675	T7673	arg3Of	],[
R6022	T7677	T7679	arg1Of	we,hypothesized
R6023	T7679	T7662	arg1Of	hypothesized,However
R6024	T7679	T7663	arg1Of	hypothesized,","
R6025	T7679	T7664	arg1Of	hypothesized,since
R6026	T7679	T7676	arg1Of	hypothesized,","
R6027	T7679	T7678	arg1Of	hypothesized,also
R6028	T7681	T7682	arg1Of	Foxp3,would
R6029	T7681	T7684	arg1Of	Foxp3,affect
R6030	T7684	T7679	arg2Of	affect,hypothesized
R6031	T7684	T7680	arg1Of	affect,that
R6032	T7684	T7682	arg2Of	affect,would
R6033	T7684	T7683	arg1Of	affect,not
R6034	T7686	T7684	arg2Of	activation,affect
R6035	T7686	T7685	arg1Of	activation,Tax-dependent
R6036	T7686	T7687	arg1Of	activation,of
R6037	T7690	T7687	arg2Of	LTR,of
R6038	T7690	T7688	arg1Of	LTR,the
R6039	T7690	T7689	arg1Of	LTR,HTLV-I
R6040	T7692	T7691	arg1Of	test,To
R6041	T7694	T7692	arg2Of	hypotheses,test
R6042	T7694	T7693	arg1Of	hypotheses,these
R6043	T7696	T7692	arg1Of	we,test
R6044	T7696	T7697	arg1Of	we,overexpressed
R6045	T7697	T7691	modOf	overexpressed,To
R6046	T7697	T7695	arg1Of	overexpressed,","
R6047	T7699	T7698	arg1Of	Tax,HTLV-I
R6048	T7699	T7700	arg1Of	Tax,","
R6049	T7700	T7704	arg1Of	",",and/or
R6050	T7702	T7700	arg2Of	Foxp3,","
R6051	T7702	T7701	arg1Of	Foxp3,full-length
R6052	T7704	T7697	arg2Of	and/or,overexpressed
R6053	T7704	T7703	arg1Of	and/or,","
R6054	T7704	T7706	arg1Of	and/or,in
R6055	T7705	T7704	arg2Of	ΔFKH,and/or
R6056	T7709	T7706	arg2Of	cells,in
R6057	T7709	T7707	arg1Of	cells,HEK
R6058	T7709	T7708	arg1Of	cells,293T
R6059	T7709	T7710	arg2Of	cells,cotransfected
R6060	T7710	T7711	arg1Of	cotransfected,with
R6061	T7714	T7715	arg1Of	LTR,or
R6062	T7716	T7715	arg2Of	NF-κB,or
R6063	T7718	T7711	arg2Of	vector,with
R6064	T7718	T7712	arg1Of	vector,an
R6065	T7718	T7713	arg1Of	vector,HTLV-I
R6066	T7718	T7714	arg1Of	vector,LTR
R6067	T7718	T7716	arg1Of	vector,NF-κB
R6068	T7718	T7717	arg1Of	vector,reporter
R6069	T7720	T7719	arg2Of	shown,As
R6070	T7720	T7721	arg1Of	shown,in
R6071	T7723	T7721	arg2Of	4A,in
R6072	T7723	T7722	arg1Of	4A,Figure
R6073	T7726	T7725	arg1Of	Tax,HTLV-I
R6074	T7726	T7728	arg1Of	Tax,up-regulated
R6075	T7728	T7719	arg1Of	up-regulated,As
R6076	T7728	T7724	arg1Of	up-regulated,","
R6077	T7728	T7727	arg1Of	up-regulated,strongly
R6078	T7731	T7728	arg2Of	activation,up-regulated
R6079	T7731	T7729	arg1Of	activation,NF-κB-dependent
R6080	T7731	T7730	arg1Of	activation,transcriptional
R6081	T7731	T7732	arg1Of	activation,(
R6082	T7733	T7732	arg2Of	~60-fold,(
R6083	T7734	T7732	arg3Of	),(
R6084	T7737	T7738	arg1Of	overexpression,of
R6085	T7737	T7745	arg1Of	overexpression,suppressed
R6086	T7739	T7741	arg1Of	Foxp3,but
R6087	T7741	T7738	arg2Of	but,of
R6088	T7741	T7740	arg1Of	but,","
R6089	T7741	T7742	arg1Of	but,not
R6090	T7743	T7741	arg2Of	ΔFKH,but
R6091	T7745	T7735	arg1Of	suppressed,Interestingly
R6092	T7745	T7736	arg1Of	suppressed,","
R6093	T7745	T7744	arg1Of	suppressed,","
R6094	T7747	T7745	arg2Of	activation,suppressed
R6095	T7747	T7746	arg1Of	activation,Tax-mediated
R6096	T7747	T7748	arg1Of	activation,of
R6097	T7750	T7748	arg2Of	transcription,of
R6098	T7750	T7749	arg1Of	transcription,NF-κB-dependent
R6099	T7752	T7751	arg1Of	observations,These
R6100	T7752	T7754	arg1Of	observations,suggest
R6101	T7754	T7753	arg1Of	suggest,further
R6102	T7759	T7756	arg1Of	domain,the
R6103	T7759	T7757	arg1Of	domain,carboxyl-terminal
R6104	T7759	T7758	arg1Of	domain,FKH
R6105	T7759	T7760	arg1Of	domain,is
R6106	T7759	T7761	arg2Of	domain,required
R6107	T7761	T7754	arg2Of	required,suggest
R6108	T7761	T7755	arg1Of	required,that
R6109	T7761	T7760	arg2Of	required,is
R6110	T7761	T7762	arg1Of	required,for
R6111	T7763	T7762	arg2Of	inhibiting,for
R6112	T7764	T7763	arg2Of	activation,inhibiting
R6113	T7764	T7765	arg1Of	activation,of
R6114	T7766	T7765	arg2Of	NF-κB,of
R6115	T7766	T7767	arg1Of	NF-κB,in
R6116	T7769	T7767	arg2Of	presence,in
R6117	T7769	T7768	arg1Of	presence,the
R6118	T7769	T7770	arg1Of	presence,of
R6119	T7769	T7772	arg1Of	presence,in
R6120	T7769	T7776	arg1Of	presence,","
R6121	T7769	T7778	arg1Of	presence,similar
R6122	T7771	T7770	arg2Of	Tax,of
R6123	T7775	T7772	arg2Of	cells,in
R6124	T7775	T7773	arg1Of	cells,HEK
R6125	T7775	T7774	arg1Of	cells,293T
R6126	T7778	T7777	arg1Of	similar,strikingly
R6127	T7778	T7779	arg1Of	similar,to
R6128	T7781	T7779	arg2Of	requirements,to
R6129	T7781	T7780	arg1Of	requirements,the
R6130	T7781	T7782	arg1Of	requirements,of
R6131	T7784	T7782	arg2Of	inhibition,of
R6132	T7784	T7783	arg1Of	inhibition,Foxp3
R6133	T7784	T7785	arg1Of	inhibition,of
R6134	T7788	T7785	arg2Of	activation,of
R6135	T7788	T7786	arg1Of	activation,basal
R6136	T7788	T7787	arg1Of	activation,NF-κB
R6137	T7788	T7789	arg2Of	activation,shown
R6138	T7789	T7790	arg1Of	shown,in
R6139	T7792	T7790	arg2Of	2B,in
R6140	T7792	T7791	arg1Of	2B,Figure
R6141	T7793	T7794	arg1Of	Transactivation,of
R6142	T7793	T7798	arg1Of	Transactivation,was
R6143	T7793	T7799	arg2Of	Transactivation,stimulated
R6144	T7797	T7794	arg2Of	LTR,of
R6145	T7797	T7795	arg1Of	LTR,the
R6146	T7797	T7796	arg1Of	LTR,HTLV-I
R6147	T7799	T7798	arg2Of	stimulated,was
R6148	T7799	T7800	arg1Of	stimulated,about
R6149	T7799	T7802	arg1Of	stimulated,by
R6150	T7799	T7810	arg1Of	stimulated,","
R6151	T7799	T7811	arg1Of	stimulated,while
R6152	T7801	T7800	arg2Of	55-fold,about
R6153	T7803	T7802	arg2Of	overexpression,by
R6154	T7803	T7804	arg1Of	overexpression,of
R6155	T7805	T7804	arg2Of	Tax,of
R6156	T7805	T7806	arg1Of	Tax,(
R6157	T7808	T7806	arg2Of	4B,(
R6158	T7808	T7807	arg1Of	4B,Figure
R6159	T7809	T7806	arg3Of	),(
R6160	T7812	T7813	arg1Of	transfection,of
R6161	T7812	T7815	arg1Of	transfection,suppressed
R6162	T7814	T7813	arg2Of	Foxp3,of
R6163	T7815	T7811	arg2Of	suppressed,while
R6164	T7815	T7820	arg1Of	suppressed,","
R6165	T7815	T7821	arg1Of	suppressed,although
R6166	T7819	T7815	arg2Of	activation,suppressed
R6167	T7819	T7816	arg1Of	activation,Tax-dependent
R6168	T7819	T7817	arg1Of	activation,HTLV-I
R6169	T7819	T7818	arg1Of	activation,LTR
R6170	T7824	T7822	arg1Of	activation,HTLV-I
R6171	T7824	T7823	arg1Of	activation,LTR
R6172	T7824	T7825	arg1Of	activation,in
R6173	T7824	T7832	arg1Of	activation,is
R6174	T7824	T7833	arg1Of	activation,independent
R6175	T7827	T7828	arg1Of	presence,or
R6176	T7828	T7825	arg2Of	or,in
R6177	T7828	T7826	arg1Of	or,the
R6178	T7828	T7830	arg1Of	or,of
R6179	T7829	T7828	arg2Of	absence,or
R6180	T7831	T7830	arg2Of	Tax,of
R6181	T7832	T7821	arg2Of	is,although
R6182	T7833	T7832	arg2Of	independent,is
R6183	T7833	T7834	arg1Of	independent,of
R6184	T7835	T7836	arg1Of	NF-κB,or
R6185	T7836	T7834	arg2Of	or,of
R6186	T7837	T7836	arg2Of	NF-AT,or
R6187	T7837	T7838	arg1Of	NF-AT,(
R6188	T7841	T7838	arg2Of	activator,(
R6189	T7841	T7839	arg1Of	activator,another
R6190	T7841	T7840	arg1Of	activator,transcriptional
R6191	T7841	T7842	arg2Of	activator,known
R6192	T7841	T7844	arg1Of	activator,interact
R6193	T7844	T7842	arg3Of	interact,known
R6194	T7844	T7843	arg1Of	interact,to
R6195	T7844	T7845	arg1Of	interact,with
R6196	T7846	T7845	arg2Of	Foxp3,with
R6197	T7847	T7838	arg3Of	),(
R6198	T7850	T7851	arg1Of	overexpression,of
R6199	T7850	T7854	arg1Of	overexpression,led
R6200	T7852	T7851	arg2Of	ΔFKH,of
R6201	T7854	T7848	arg1Of	led,Furthermore
R6202	T7854	T7849	arg1Of	led,","
R6203	T7854	T7853	arg1Of	led,also
R6204	T7854	T7855	arg1Of	led,to
R6205	T7854	T7862	arg1Of	led,to
R6206	T7854	T7866	arg1Of	led,as
R6207	T7856	T7855	arg2Of	suppression,to
R6208	T7856	T7857	arg1Of	suppression,of
R6209	T7859	T7857	arg2Of	transactivation,of
R6210	T7859	T7858	arg1Of	transactivation,HTLV-I
R6211	T7859	T7860	arg1Of	transactivation,by
R6212	T7861	T7860	arg2Of	Tax,by
R6213	T7865	T7862	arg2Of	extent,to
R6214	T7865	T7863	arg1Of	extent,a
R6215	T7865	T7864	arg1Of	extent,similar
R6216	T7868	T7866	arg2Of	Foxp3,as
R6217	T7868	T7867	arg1Of	Foxp3,full-length
R6218	T7868	T7869	arg1Of	Foxp3,(
R6219	T7871	T7869	arg2Of	4B,(
R6220	T7871	T7870	arg1Of	4B,Figure
R6221	T7872	T7869	arg3Of	),(
R6222	T7875	T7873	arg1Of	effects,The
R6223	T7875	T7874	arg1Of	effects,suppressive
R6224	T7875	T7876	arg2Of	effects,shown
R6225	T7875	T7882	arg1Of	effects,were
R6226	T7876	T7877	arg1Of	shown,in
R6227	T7879	T7878	arg1Of	4A,Figure
R6228	T7879	T7880	arg1Of	4A,and
R6229	T7880	T7877	arg2Of	and,in
R6230	T7881	T7880	arg2Of	4B,and
R6231	T7882	T7883	arg1Of	were,not
R6232	T7885	T7882	arg2Of	result,were
R6233	T7885	T7884	arg1Of	result,the
R6234	T7885	T7886	arg1Of	result,of
R6235	T7887	T7886	arg2Of	Foxp3,of
R6236	T7887	T7888	arg1Of	Foxp3,down-regulating
R6237	T7888	T7896	arg1Of	down-regulating,as
R6238	T7890	T7888	arg2Of	expression,down-regulating
R6239	T7890	T7889	arg1Of	expression,the
R6240	T7890	T7891	arg1Of	expression,of
R6241	T7895	T7891	arg2Of	plasmid,of
R6242	T7895	T7892	arg1Of	plasmid,the
R6243	T7895	T7893	arg2Of	plasmid,transfected
R6244	T7895	T7894	arg1Of	plasmid,Tax
R6245	T7897	T7896	arg2Of	determined,as
R6246	T7900	T7897	arg1Of	RT-PCR,determined
R6247	T7900	T7898	arg2Of	RT-PCR,by
R6248	T7900	T7899	arg1Of	RT-PCR,real-time
R6249	T7900	T7901	arg1Of	RT-PCR,(
R6250	T7903	T7901	arg2Of	4C,(
R6251	T7903	T7902	arg1Of	4C,Figure
R6252	T7904	T7901	arg3Of	),(
R6253	T7906	T7905	arg1Of	results,These
R6254	T7906	T7908	arg1Of	results,suggest
R6255	T7908	T7907	arg1Of	suggest,strongly
R6256	T7910	T7911	arg1Of	Foxp3,interacts
R6257	T7911	T7909	arg1Of	interacts,that
R6258	T7911	T7912	arg1Of	interacts,with
R6259	T7911	T7915	arg1Of	interacts,in
R6260	T7911	T7922	arg1Of	interacts,and
R6261	T7914	T7912	arg2Of	regulators,with
R6262	T7914	T7913	arg1Of	regulators,transcriptional
R6263	T7916	T7915	arg2Of	addition,in
R6264	T7916	T7917	arg1Of	addition,to
R6265	T7918	T7919	arg1Of	NF-κB,and
R6266	T7919	T7917	arg2Of	and,to
R6267	T7920	T7919	arg2Of	NF-AT,and
R6268	T7922	T7908	arg2Of	and,suggest
R6269	T7922	T7921	arg1Of	and,","
R6270	T7923	T7922	arg2Of	that,and
R6271	T7927	T7924	arg1Of	domain,the
R6272	T7927	T7925	arg1Of	domain,carboxyl-terminal
R6273	T7927	T7926	arg1Of	domain,FKH
R6274	T7927	T7929	arg1Of	domain,and
R6275	T7929	T7928	arg1Of	and,","
R6276	T7929	T7936	arg1Of	and,are
R6277	T7929	T7938	arg2Of	and,required
R6278	T7931	T7929	arg2Of	localization,and
R6279	T7931	T7930	arg1Of	localization,therefore
R6280	T7931	T7932	arg1Of	localization,to
R6281	T7934	T7932	arg2Of	nucleus,to
R6282	T7934	T7933	arg1Of	nucleus,the
R6283	T7938	T7923	arg2Of	required,that
R6284	T7938	T7935	arg1Of	required,","
R6285	T7938	T7936	arg2Of	required,are
R6286	T7938	T7937	arg1Of	required,not
R6287	T7938	T7939	arg1Of	required,for
R6288	T7940	T7939	arg2Of	inhibition,for
R6289	T7940	T7941	arg1Of	inhibition,of
R6290	T7945	T7941	arg2Of	activation,of
R6291	T7945	T7942	arg1Of	activation,Tax-mediated
R6292	T7945	T7943	arg1Of	activation,HTLV-I
R6293	T7945	T7944	arg1Of	activation,LTR
R6294	T7945	T7946	arg1Of	activation,(
R6295	T7948	T7946	arg2Of	in,(
R6296	T7948	T7947	arg1Of	in,even
R6297	T7951	T7948	arg2Of	cells,in
R6298	T7951	T7949	arg1Of	cells,HEK
R6299	T7951	T7950	arg1Of	cells,293T
R6300	T7952	T7946	arg3Of	),(
R6301	T7954	T7953	arg1Of	determine,To
R6302	T7956	T7957	arg1Of	Foxp3,inhibited
R6303	T7957	T7954	arg2Of	inhibited,determine
R6304	T7957	T7955	arg1Of	inhibited,whether
R6305	T7957	T7963	arg1Of	inhibited,by
R6306	T7960	T7957	arg2Of	functions,inhibited
R6307	T7960	T7958	arg1Of	functions,the
R6308	T7960	T7959	arg1Of	functions,transactivation
R6309	T7960	T7961	arg1Of	functions,of
R6310	T7962	T7961	arg2Of	Tax,of
R6311	T7965	T7963	arg2Of	associating,by
R6312	T7965	T7964	arg1Of	associating,directly
R6313	T7965	T7966	arg1Of	associating,with
R6314	T7969	T7966	arg2Of	protein,with
R6315	T7969	T7967	arg1Of	protein,this
R6316	T7969	T7968	arg1Of	protein,viral
R6317	T7971	T7954	arg1Of	we,determine
R6318	T7971	T7972	arg1Of	we,generated
R6319	T7972	T7953	modOf	generated,To
R6320	T7972	T7970	arg1Of	generated,","
R6321	T7975	T7972	arg2Of	vector,generated
R6322	T7975	T7973	arg1Of	vector,an
R6323	T7975	T7974	arg1Of	vector,expression
R6324	T7975	T7976	arg2Of	vector,in
R6325	T7975	T7977	arg1Of	vector,which
R6326	T7979	T7978	arg1Of	Tax,HTLV-I
R6327	T7979	T7980	arg1Of	Tax,was
R6328	T7979	T7981	arg2Of	Tax,fused
R6329	T7981	T7976	arg1Of	fused,in
R6330	T7981	T7980	arg2Of	fused,was
R6331	T7981	T7983	arg1Of	fused,to
R6332	T7983	T7982	arg1Of	to,in-frame
R6333	T7986	T7983	arg2Of	terminus,to
R6334	T7986	T7984	arg1Of	terminus,the
R6335	T7986	T7985	arg1Of	terminus,carboxyl
R6336	T7986	T7987	arg1Of	terminus,of
R6337	T7991	T7987	arg2Of	domain,of
R6338	T7991	T7988	arg1Of	domain,the
R6339	T7991	T7989	arg1Of	domain,Gal4
R6340	T7991	T7990	arg1Of	domain,DNA-binding
R6341	T7991	T7992	arg1Of	domain,(
R6342	T7993	T7992	arg2Of	Gal4-BD,(
R6343	T7994	T7992	arg3Of	),(
R6344	T7998	T7995	arg1Of	protein,This
R6345	T7998	T7996	arg1Of	protein,Gal4-BD-Tax
R6346	T7998	T7997	arg1Of	protein,fusion
R6347	T7998	T7999	arg1Of	protein,activated
R6348	T7999	T8010	arg1Of	activated,","
R6349	T7999	T8011	arg1Of	activated,while
R6350	T8000	T7999	arg2Of	transcription,activated
R6351	T8000	T8001	arg1Of	transcription,of
R6352	T8004	T8001	arg2Of	promoter,of
R6353	T8004	T8002	arg1Of	promoter,a
R6354	T8004	T8003	arg1Of	promoter,synthetic
R6355	T8004	T8005	arg1Of	promoter,containing
R6356	T8009	T8005	arg2Of	sites,containing
R6357	T8009	T8006	arg1Of	sites,five
R6358	T8009	T8007	arg1Of	sites,Gal4
R6359	T8009	T8008	arg1Of	sites,binding
R6360	T8012	T8013	arg1Of	Gal4-BD,was
R6361	T8012	T8014	arg1Of	Gal4-BD,insufficient
R6362	T8012	T8016	arg1Of	Gal4-BD,stimulate
R6363	T8013	T8011	arg2Of	was,while
R6364	T8014	T8013	arg2Of	insufficient,was
R6365	T8016	T8014	arg2Of	stimulate,insufficient
R6366	T8016	T8015	arg1Of	stimulate,to
R6367	T8016	T8018	arg1Of	stimulate,by
R6368	T8017	T8016	arg2Of	transcription,stimulate
R6369	T8019	T8018	arg2Of	itself,by
R6370	T8019	T8020	arg1Of	itself,(
R6371	T8022	T8020	arg2Of	4D,(
R6372	T8022	T8021	arg1Of	4D,Figure
R6373	T8023	T8020	arg3Of	),(
R6374	T8024	T8025	arg1Of	Transactivation,of
R6375	T8024	T8029	arg1Of	Transactivation,by
R6376	T8024	T8031	arg1Of	Transactivation,remained
R6377	T8024	T8033	arg1Of	Transactivation,unaffected
R6378	T8028	T8025	arg2Of	promoter,of
R6379	T8028	T8026	arg1Of	promoter,the
R6380	T8028	T8027	arg1Of	promoter,Gal4-resposive
R6381	T8030	T8029	arg2Of	Gal4-BD-Tax,by
R6382	T8031	T8047	arg1Of	remained,","
R6383	T8031	T8048	modOf	remained,suggesting
R6384	T8033	T8031	arg2Of	unaffected,remained
R6385	T8033	T8032	arg1Of	unaffected,relatively
R6386	T8033	T8034	arg1Of	unaffected,by
R6387	T8035	T8034	arg2Of	overexpression,by
R6388	T8035	T8036	arg1Of	overexpression,of
R6389	T8038	T8039	arg1Of	EGFP,(
R6390	T8038	T8042	arg1Of	EGFP,","
R6391	T8040	T8039	arg2Of	control,(
R6392	T8041	T8039	arg3Of	),(
R6393	T8042	T8037	arg1Of	",",either
R6394	T8113	T8111	arg3Of	direct,shown
R6395	T8113	T8112	arg1Of	direct,to
R6396	T8042	T8045	arg1Of	",",or
R6397	T8115	T8113	arg2Of	expression,direct
R6398	T8115	T8114	arg1Of	expression,the
R6399	T8115	T8116	arg1Of	expression,of
R6400	T8043	T8042	arg2Of	Foxp3,","
R6401	T8118	T8116	arg2Of	antigens,of
R6402	T8118	T8117	arg1Of	antigens,viral
R6403	T8119	T8124	arg1Of	",",and
R6404	T8120	T8119	arg2Of	produce,","
R6405	T8045	T8036	arg2Of	or,of
R6406	T8122	T8120	arg2Of	virus,produce
R6407	T8122	T8121	arg1Of	virus,infectious
R6408	T8124	T8123	arg1Of	and,","
R6409	T8124	T8135	arg1Of	and,[
R6410	T8045	T8044	arg1Of	or,","
R6411	T8125	T8124	arg2Of	transform,and
R6412	T8046	T8045	arg2Of	ΔFKH,or
R6413	T8128	T8125	arg2Of	cells,transform
R6414	T8128	T8126	arg1Of	cells,CD4+
R6415	T8128	T8127	arg1Of	cells,T
R6416	T8128	T8131	arg1Of	cells,vitro
R6417	T8128	T8134	arg1Of	cells,vivo
R6418	T8050	T8051	arg1Of	Foxp3,does
R6419	T8131	T8130	arg1Of	vitro,in
R6420	T8131	T8132	arg1Of	vitro,and
R6421	T8132	T8129	arg1Of	and,both
R6422	T8134	T8132	arg2Of	vivo,and
R6423	T8134	T8133	arg1Of	vivo,in
R6424	T8136	T8135	arg2Of	"31,32",[
R6425	T8050	T8053	arg1Of	Foxp3,repress
R6426	T8137	T8135	arg3Of	],[
R6427	T8053	T8048	arg2Of	repress,suggesting
R6428	T8140	T8138	arg2Of	h,After
R6429	T8140	T8139	arg1Of	h,24
R6430	T8053	T8049	arg1Of	repress,that
R6431	T8053	T8051	arg2Of	repress,does
R6432	T8143	T8142	arg1Of	amount,the
R6433	T8143	T8144	arg1Of	amount,of
R6434	T8143	T8155	arg1Of	amount,was
R6435	T8143	T8156	arg2Of	amount,detected
R6436	T8053	T8052	arg1Of	repress,not
R6437	T8053	T8056	arg1Of	repress,by
R6438	T8055	T8053	arg2Of	transactivation,repress
R6439	T8147	T8144	arg2Of	expression,of
R6440	T8147	T8145	arg1Of	expression,viral
R6441	T8147	T8146	arg1Of	expression,antigen
R6442	T8055	T8054	arg1Of	transactivation,Tax
R6443	T8058	T8056	arg2Of	interfacing,by
R6444	T8153	T8149	arg2Of	mRNA,in
R6445	T8153	T8150	arg1Of	mRNA,this
R6446	T8153	T8151	arg1Of	mRNA,case
R6447	T8153	T8152	arg1Of	mRNA,Tax
R6448	T8156	T8138	arg1Of	detected,After
R6449	T8156	T8141	arg1Of	detected,","
R6450	T8156	T8148	arg1Of	detected,","
R6451	T8156	T8149	arg1Of	detected,in
R6452	T8156	T8154	arg1Of	detected,","
R6453	T8156	T8155	arg2Of	detected,was
R6454	T8058	T8057	arg1Of	interfacing,directly
R6455	T8162	T8156	arg1Of	assay,detected
R6456	T8162	T8157	arg2Of	assay,by
R6457	T8162	T8158	arg1Of	assay,a
R6458	T8162	T8159	arg1Of	assay,sensitive
R6459	T8162	T8160	arg1Of	assay,real-time
R6460	T8162	T8161	arg1Of	assay,RT-PCR
R6461	T8058	T8059	arg1Of	interfacing,with
R6462	T8063	T8059	arg2Of	protein,with
R6463	T8164	T8163	arg2Of	illustrated,As
R6464	T8164	T8165	arg1Of	illustrated,in
R6465	T8166	T8165	arg2Of	Figure,in
R6466	T8166	T8167	arg1Of	Figure,5
R6467	T8170	T8169	arg1Of	level,the
R6468	T8170	T8171	arg1Of	level,of
R6469	T8170	T8177	arg1Of	level,was
R6470	T8170	T8178	arg2Of	level,down-regulated
R6471	T8063	T8060	arg1Of	protein,the
R6472	T8173	T8171	arg2Of	mRNA,of
R6473	T8173	T8172	arg1Of	mRNA,Tax
R6474	T8173	T8174	arg2Of	mRNA,synthesized
R6475	T8174	T8175	arg1Of	synthesized,from
R6476	T8063	T8061	arg1Of	protein,HTLV-I
R6477	T8063	T8062	arg1Of	protein,Tax
R6478	T8176	T8175	arg2Of	ACH,from
R6479	T8065	T8064	arg1Of	confirm,To
R6480	T8178	T8163	arg1Of	down-regulated,As
R6481	T8178	T8168	arg1Of	down-regulated,","
R6482	T8178	T8177	arg2Of	down-regulated,was
R6483	T8178	T8179	arg1Of	down-regulated,in
R6484	T8178	T8184	arg1Of	down-regulated,compared
R6485	T8181	T8179	arg2Of	presence,in
R6486	T8181	T8180	arg1Of	presence,the
R6487	T8181	T8182	arg1Of	presence,of
R6488	T8067	T8068	arg1Of	Foxp3,had
R6489	T8183	T8182	arg2Of	Foxp3,of
R6490	T8185	T8184	arg2Of	to,compared
R6491	T8185	T8192	arg1Of	to,of
R6492	T8187	T8185	arg2Of	level,to
R6493	T8187	T8186	arg1Of	level,the
R6494	T8187	T8188	arg2Of	level,produced
R6495	T8188	T8189	arg1Of	produced,in
R6496	T8068	T8065	arg2Of	had,confirm
R6497	T8189	T8190	arg1Of	in,the
R6498	T8191	T8189	arg2Of	presence,in
R6499	T8068	T8066	arg1Of	had,that
R6500	T8068	T8072	arg1Of	had,on
R6501	T8196	T8193	arg1Of	ΔFKH,the
R6502	T8196	T8194	arg1Of	ΔFKH,control
R6503	T8196	T8195	arg1Of	ΔFKH,vector.
R6504	T8196	T8197	arg1Of	ΔFKH,did
R6505	T8196	T8199	arg1Of	ΔFKH,have
R6506	T8071	T8068	arg2Of	effect,had
R6507	T8199	T8177	modOf	have,was
R6508	T8199	T8197	arg2Of	have,did
R6509	T8199	T8198	arg1Of	have,not
R6510	T8202	T8199	arg2Of	affect,have
R6511	T8202	T8200	arg1Of	affect,a
R6512	T8202	T8201	arg1Of	affect,discernable
R6513	T8202	T8203	arg1Of	affect,on
R6514	T8071	T8069	arg1Of	effect,a
R6515	T8205	T8203	arg2Of	expression,on
R6516	T8205	T8204	arg1Of	expression,Tax
R6517	T8071	T8070	arg1Of	effect,direct
R6518	T8207	T8206	arg1Of	data,These
R6519	T8207	T8208	arg1Of	data,indicate
R6520	T8074	T8072	arg2Of	replication,on
R6521	T8074	T8073	arg1Of	replication,HTLV-I
R6522	T8210	T8211	arg1Of	Foxp3,is
R6523	T8210	T8212	arg1Of	Foxp3,capable
R6524	T8210	T8214	arg1Of	Foxp3,repressing
R6525	T8076	T8065	arg1Of	we,confirm
R6526	T8211	T8208	arg2Of	is,indicate
R6527	T8211	T8209	arg1Of	is,that
R6528	T8212	T8211	arg2Of	capable,is
R6529	T8212	T8213	arg1Of	capable,of
R6530	T8214	T8213	arg2Of	repressing,of
R6531	T8076	T8077	arg1Of	we,transfected
R6532	T8216	T8214	arg2Of	expression,repressing
R6533	T8216	T8215	arg1Of	expression,the
R6534	T8216	T8217	arg1Of	expression,of
R6535	T8077	T8064	modOf	transfected,To
R6536	T8218	T8217	arg2Of	Tax,of
R6537	T8218	T8219	arg1Of	Tax,from
R6538	T8077	T8075	arg1Of	transfected,","
R6539	T8077	T8081	arg1Of	transfected,with
R6540	T8077	T8092	arg1Of	transfected,[
R6541	T8077	T8095	arg1Of	transfected,in
R6542	T8224	T8219	arg2Of	clone,from
R6543	T8224	T8220	arg1Of	clone,an
R6544	T8224	T8221	arg1Of	clone,infectious
R6545	T8224	T8222	arg1Of	clone,HTLV-I
R6546	T8224	T8223	arg1Of	clone,molecular
R6547	T8080	T8077	arg2Of	cells,transfected
R6548	T8080	T8078	arg1Of	cells,HEK
R6549	T8080	T8079	arg1Of	cells,293T
R6550	T8087	T8081	arg2Of	clone,with
R6552	T8087	T8082	arg1Of	clone,a
R6554	T8087	T8083	arg1Of	clone,well-characterized
R6555	T8087	T8084	arg1Of	clone,HTLV-I
R6556	T8087	T8085	arg1Of	clone,infectious
R6557	T8087	T8086	arg1Of	clone,molecular
R6558	T8087	T8088	arg1Of	clone,(
R6559	T8089	T8088	arg2Of	termed,(
R6560	T8090	T8089	arg3Of	ACH,termed
R6561	T8091	T8088	arg3Of	),(
R6562	T8093	T8092	arg2Of	30,[
R6563	T8094	T8092	arg3Of	],[
R6564	T8097	T8095	arg2Of	presence,in
R6565	T8097	T8096	arg1Of	presence,the
R6566	T8097	T8098	arg1Of	presence,of
R6567	T8100	T8099	arg1Of	Foxp3,full-length
R6568	T8100	T8101	arg1Of	Foxp3,","
R6569	T8101	T8104	arg1Of	",",or
R6570	T8102	T8101	arg2Of	ΔFKH,","
R6571	T8104	T8098	arg2Of	or,of
R6572	T8104	T8103	arg1Of	or,","
R6573	T8106	T8104	arg2Of	vector,or
R6574	T8106	T8105	arg1Of	vector,control
R6575	T8107	T8108	arg1Of	ACH,has
R6576	T8107	T8109	arg1Of	ACH,been
R6577	T8107	T8111	arg2Of	ACH,shown
R6578	T8107	T8113	arg1Of	ACH,direct
R6579	T8107	T8120	arg1Of	ACH,produce
R6580	T8107	T8125	arg1Of	ACH,transform
R6581	T8111	T8108	arg2Of	shown,has
R6582	T8111	T8109	arg2Of	shown,been
R6583	T8111	T8110	arg1Of	shown,previously
R6584	T8111	T8119	arg1Of	shown,","
R5888	T7544	T7548	arg1Of	Functions,Are
R5889	T7544	T7549	arg2Of	Functions,Suppressed
R5893	T7547	T7545	arg2Of	Tax,of
R5894	T7547	T7546	arg1Of	Tax,HTLV-I
R5895	T7549	T7548	arg2Of	Suppressed,Are
R5896	T7551	T7549	arg1Of	Foxp3,Suppressed
R5897	T7551	T7550	arg2Of	Foxp3,by

bionlp-st-ge-2016-coref

Id	Subject	Object	Predicate	Lexical cue
T8225	3942-3960	Anaphor	denotes	this viral protein
T8226	3909-3912	Antecedent	denotes	Tax
T8227	4988-5001	Anaphor	denotes	viral antigen
T8228	5027-5030	Antecedent	denotes	Tax
R6551	T8225	T8226	boundBy	this viral protein,Tax
R6553	T8227	T8228	boundBy	viral antigen,Tax

bionlp-st-ge-2016-spacy-parsed

Id	Subject	Object	Predicate	Lexical cue
T6834	0-3	DT	denotes	The
T6835	4-19	NNP	denotes	Transactivation
T6836	20-29	NNS	denotes	Functions
T6837	30-32	IN	denotes	of
T6838	33-39	NNP	denotes	HTLV-I
T6839	40-43	NNP	denotes	Tax
T6840	44-47	VBP	denotes	Are
T6841	48-58	VBN	denotes	Suppressed
T6842	59-61	IN	denotes	by
T6843	62-67	NNP	denotes	Foxp3
T6844	68-76	JJ	denotes	Previous
T6845	77-84	NNS	denotes	studies
T6846	85-87	IN	denotes	by
T6847	88-96	NNP	denotes	Bettelli
T6848	97-100	CC	denotes	and
T6849	101-111	NNS	denotes	colleagues
T6850	112-116	VBP	denotes	have
T6851	117-129	VBN	denotes	demonstrated
T6852	130-134	IN	denotes	that
T6853	135-140	NNP	denotes	Foxp3
T6854	141-144	MD	denotes	can
T6855	145-152	VB	denotes	repress
T6856	153-157	DT	denotes	both
T6857	158-161	DT	denotes	the
T6858	162-167	JJ	denotes	basal
T6859	168-174	NNS	denotes	levels
T6860	175-177	IN	denotes	of
T6861	178-183	JJ	denotes	NF-κB
T6862	184-194	NN	denotes	activation
T6863	195-197	RB	denotes	as
T6864	198-202	RB	denotes	well
T6865	203-205	IN	denotes	as
T6866	206-211	NN	denotes	tumor
T6867	212-220	NN	denotes	necrosis
T6868	221-240	JJ	denotes	factor-α-stimulated
T6869	241-246	NN	denotes	NF-κB
T6870	247-257	NN	denotes	activation
T6871	258-259	NNP	denotes	[
T6872	259-261	CD	denotes	15
T6873	261-262	NNP	denotes	]
T6874	262-263	.	denotes	.
T6875	264-267	PRP$	denotes	Our
T6876	268-272	JJ	denotes	next
T6877	273-277	NN	denotes	step
T6878	278-281	VBD	denotes	was
T6879	282-284	TO	denotes	to
T6880	285-294	VB	denotes	determine
T6881	295-302	IN	denotes	whether
T6882	303-308	NNP	denotes	Foxp3
T6883	309-314	MD	denotes	could
T6884	315-319	RB	denotes	also
T6885	320-328	VB	denotes	suppress
T6886	329-332	DT	denotes	the
T6887	333-343	NN	denotes	activation
T6888	344-346	IN	denotes	of
T6889	347-352	NN	denotes	NF-κB
T6890	353-359	VBN	denotes	caused
T6891	360-362	IN	denotes	by
T6892	363-364	DT	denotes	a
T6893	365-371	JJ	denotes	strong
T6894	372-377	JJ	denotes	viral
T6895	378-392	NN	denotes	transactivator
T6896	393-400	NN	denotes	protein
T6897	400-401	.	denotes	.
T6898	402-408	NNP	denotes	HTLV-I
T6899	409-416	VBZ	denotes	encodes
T6900	417-418	DT	denotes	a
T6901	419-434	JJ	denotes	multifunctional
T6902	435-449	NN	denotes	transactivator
T6903	450-457	NN	denotes	protein
T6904	457-458	,	denotes	,
T6905	459-462	NNP	denotes	Tax
T6906	462-463	,	denotes	,
T6907	464-471	JJ	denotes	capable
T6908	472-474	IN	denotes	of
T6909	475-485	VBG	denotes	activating
T6910	486-490	CC	denotes	both
T6911	491-494	DT	denotes	the
T6912	495-500	NNP	denotes	NF-κB
T6913	501-504	CC	denotes	and
T6914	505-509	NNP	denotes	CREB
T6915	510-518	NNS	denotes	pathways
T6916	519-520	NNP	denotes	[
T6917	520-522	CD	denotes	24
T6918	523-525	CD	denotes	29
T6919	525-526	NN	denotes	]
T6920	526-527	.	denotes	.
T6921	528-533	IN	denotes	Since
T6922	534-537	DT	denotes	the
T6923	538-544	NNP	denotes	HTLV-I
T6924	545-548	NNP	denotes	Tax
T6925	549-556	NN	denotes	protein
T6926	557-560	MD	denotes	can
T6927	561-569	VB	denotes	function
T6928	570-572	IN	denotes	at
T6929	573-581	JJ	denotes	multiple
T6930	582-588	NNS	denotes	levels
T6931	589-591	IN	denotes	in
T6932	592-596	DT	denotes	both
T6933	597-600	DT	denotes	the
T6934	601-610	NN	denotes	cytoplasm
T6935	611-614	CC	denotes	and
T6936	615-618	DT	denotes	the
T6937	619-626	NN	denotes	nucleus
T6938	627-629	TO	denotes	to
T6939	630-639	VB	denotes	stimulate
T6940	640-650	NN	denotes	activation
T6941	651-653	IN	denotes	of
T6942	654-659	NNP	denotes	NF-κB
T6943	660-661	NNP	denotes	[
T6944	661-666	CD	denotes	28,29
T6945	666-667	NNP	denotes	]
T6946	667-668	,	denotes	,
T6947	669-671	PRP	denotes	we
T6948	672-684	VBD	denotes	hypothesized
T6949	685-689	IN	denotes	that
T6950	690-704	NN	denotes	overexpression
T6951	705-707	IN	denotes	of
T6952	708-713	NNP	denotes	Foxp3
T6953	714-717	MD	denotes	may
T6954	718-727	VB	denotes	interfere
T6955	728-732	IN	denotes	with
T6956	733-737	DT	denotes	this
T6957	738-745	NN	denotes	process
T6958	745-746	.	denotes	.
T6959	747-754	RB	denotes	However
T6960	754-755	,	denotes	,
T6961	756-761	IN	denotes	since
T6962	762-775	JJ	denotes	Tax-dependent
T6963	776-782	NNP	denotes	HTLV-I
T6964	783-787	NN	denotes	gene
T6965	788-798	NN	denotes	expression
T6966	799-801	VBZ	denotes	is
T6967	802-813	JJ	denotes	independent
T6968	814-816	IN	denotes	of
T6969	817-822	NNP	denotes	NF-κB
T6970	823-824	NNP	denotes	[
T6971	824-826	CD	denotes	18
T6972	826-827	NNP	denotes	]
T6973	827-828	,	denotes	,
T6974	829-831	PRP	denotes	we
T6975	832-836	RB	denotes	also
T6976	837-849	VBD	denotes	hypothesized
T6977	850-854	IN	denotes	that
T6978	855-860	NNP	denotes	Foxp3
T6979	861-866	MD	denotes	would
T6980	867-870	RB	denotes	not
T6981	871-877	VB	denotes	affect
T6982	878-891	JJ	denotes	Tax-dependent
T6983	892-902	NN	denotes	activation
T6984	903-905	IN	denotes	of
T6985	906-909	DT	denotes	the
T6986	910-916	NNP	denotes	HTLV-I
T6987	917-920	NNP	denotes	LTR
T6988	920-921	.	denotes	.
T6989	922-924	TO	denotes	To
T6990	925-929	VB	denotes	test
T6991	930-935	DT	denotes	these
T6992	936-946	NNS	denotes	hypotheses
T6993	946-947	,	denotes	,
T6994	948-950	PRP	denotes	we
T6995	951-964	VBD	denotes	overexpressed
T6996	965-971	NNP	denotes	HTLV-I
T6997	972-975	NNP	denotes	Tax
T6998	975-976	,	denotes	,
T6999	977-988	JJ	denotes	full-length
T7000	989-994	NNP	denotes	Foxp3
T7001	994-995	,	denotes	,
T7002	996-1002	CC	denotes	and/or
T7003	1003-1007	NNP	denotes	ΔFKH
T7004	1008-1010	IN	denotes	in
T7005	1011-1014	NNP	denotes	HEK
T7006	1015-1019	CD	denotes	293T
T7007	1020-1025	NNS	denotes	cells
T7008	1026-1039	VBN	denotes	cotransfected
T7009	1040-1044	IN	denotes	with
T7010	1045-1047	DT	denotes	an
T7011	1048-1054	NNP	denotes	HTLV-I
T7012	1055-1058	NNP	denotes	LTR
T7013	1059-1061	CC	denotes	or
T7014	1062-1067	NNP	denotes	NF-κB
T7015	1068-1076	NN	denotes	reporter
T7016	1077-1083	NN	denotes	vector
T7017	1083-1084	.	denotes	.
T7018	1085-1087	IN	denotes	As
T7019	1088-1093	VBN	denotes	shown
T7020	1094-1096	IN	denotes	in
T7021	1097-1103	NN	denotes	Figure
T7022	1104-1106	CD	denotes	4A
T7023	1106-1107	,	denotes	,
T7024	1108-1114	NNP	denotes	HTLV-I
T7025	1115-1118	NNP	denotes	Tax
T7026	1119-1127	RB	denotes	strongly
T7027	1128-1140	JJ	denotes	up-regulated
T7028	1141-1156	JJ	denotes	NF-κB-dependent
T7029	1157-1172	JJ	denotes	transcriptional
T7030	1173-1183	NN	denotes	activation
T7031	1184-1185	-LRB-	denotes	(
T7032	1185-1186	FW	denotes	~
T7033	1186-1193	JJ	denotes	60-fold
T7034	1193-1194	-RRB-	denotes	)
T7035	1194-1195	.	denotes	.
T7036	1196-1209	RB	denotes	Interestingly
T7037	1209-1210	,	denotes	,
T7038	1211-1225	NN	denotes	overexpression
T7039	1226-1228	IN	denotes	of
T7040	1229-1234	NNP	denotes	Foxp3
T7041	1234-1235	,	denotes	,
T7042	1236-1239	CC	denotes	but
T7043	1240-1243	RB	denotes	not
T7044	1244-1248	NNP	denotes	ΔFKH
T7045	1248-1249	,	denotes	,
T7046	1250-1260	VBN	denotes	suppressed
T7047	1261-1273	JJ	denotes	Tax-mediated
T7048	1274-1284	NN	denotes	activation
T7049	1285-1287	IN	denotes	of
T7050	1288-1303	JJ	denotes	NF-κB-dependent
T7051	1304-1317	NN	denotes	transcription
T7052	1317-1318	.	denotes	.
T7053	1319-1324	DT	denotes	These
T7054	1325-1337	NNS	denotes	observations
T7055	1338-1345	JJ	denotes	further
T7056	1346-1353	VBP	denotes	suggest
T7057	1354-1358	IN	denotes	that
T7058	1359-1362	DT	denotes	the
T7059	1363-1380	JJ	denotes	carboxyl-terminal
T7060	1381-1384	NNP	denotes	FKH
T7061	1385-1391	NN	denotes	domain
T7062	1392-1394	VBZ	denotes	is
T7063	1395-1403	VBN	denotes	required
T7064	1404-1407	IN	denotes	for
T7065	1408-1418	VBG	denotes	inhibiting
T7066	1419-1429	NN	denotes	activation
T7067	1430-1432	IN	denotes	of
T7068	1433-1438	NN	denotes	NF-κB
T7069	1439-1441	IN	denotes	in
T7070	1442-1445	DT	denotes	the
T7071	1446-1454	NN	denotes	presence
T7072	1455-1457	IN	denotes	of
T7073	1458-1461	NNP	denotes	Tax
T7074	1462-1464	IN	denotes	in
T7075	1465-1468	NNP	denotes	HEK
T7076	1469-1473	CD	denotes	293T
T7077	1474-1479	NNS	denotes	cells
T7078	1479-1480	,	denotes	,
T7079	1481-1491	RB	denotes	strikingly
T7080	1492-1499	JJ	denotes	similar
T7081	1500-1502	TO	denotes	to
T7082	1503-1506	DT	denotes	the
T7083	1507-1519	NNS	denotes	requirements
T7084	1520-1522	IN	denotes	of
T7085	1523-1528	JJ	denotes	Foxp3
T7086	1529-1539	NN	denotes	inhibition
T7087	1540-1542	IN	denotes	of
T7088	1543-1548	JJ	denotes	basal
T7089	1549-1554	NN	denotes	NF-κB
T7090	1555-1565	NN	denotes	activation
T7091	1566-1571	VBN	denotes	shown
T7092	1572-1574	IN	denotes	in
T7093	1575-1581	NN	denotes	Figure
T7094	1582-1584	NN	denotes	2B
T7095	1584-1585	.	denotes	.
T7096	1586-1601	NNP	denotes	Transactivation
T7097	1602-1604	IN	denotes	of
T7098	1605-1608	DT	denotes	the
T7099	1609-1615	NNP	denotes	HTLV-I
T7100	1616-1619	NNP	denotes	LTR
T7101	1620-1623	VBD	denotes	was
T7102	1624-1634	VBN	denotes	stimulated
T7103	1635-1640	IN	denotes	about
T7104	1641-1648	JJ	denotes	55-fold
T7105	1649-1651	IN	denotes	by
T7106	1652-1666	NN	denotes	overexpression
T7107	1667-1669	IN	denotes	of
T7108	1670-1673	NNP	denotes	Tax
T7109	1674-1675	-LRB-	denotes	(
T7110	1675-1681	NNP	denotes	Figure
T7111	1682-1684	NNP	denotes	4B
T7112	1684-1685	-RRB-	denotes	)
T7113	1685-1686	,	denotes	,
T7114	1687-1692	IN	denotes	while
T7115	1693-1705	NN	denotes	transfection
T7116	1706-1708	IN	denotes	of
T7117	1709-1714	JJ	denotes	Foxp3
T7118	1715-1725	VBN	denotes	suppressed
T7119	1726-1739	NN	denotes	Tax-dependent
T7120	1740-1746	NNP	denotes	HTLV-I
T7121	1747-1750	NNP	denotes	LTR
T7122	1751-1761	NN	denotes	activation
T7123	1761-1762	,	denotes	,
T7124	1763-1771	IN	denotes	although
T7125	1772-1778	NNP	denotes	HTLV-I
T7126	1779-1782	NNP	denotes	LTR
T7127	1783-1793	NN	denotes	activation
T7128	1794-1796	IN	denotes	in
T7129	1797-1800	DT	denotes	the
T7130	1801-1809	NN	denotes	presence
T7131	1810-1812	CC	denotes	or
T7132	1813-1820	NN	denotes	absence
T7133	1821-1823	IN	denotes	of
T7134	1824-1827	NNP	denotes	Tax
T7135	1828-1830	VBZ	denotes	is
T7136	1831-1842	JJ	denotes	independent
T7137	1843-1845	IN	denotes	of
T7138	1846-1851	NNP	denotes	NF-κB
T7139	1852-1854	CC	denotes	or
T7140	1855-1860	NNP	denotes	NF-AT
T7141	1861-1862	-LRB-	denotes	(
T7142	1862-1869	DT	denotes	another
T7143	1870-1885	JJ	denotes	transcriptional
T7144	1886-1895	NN	denotes	activator
T7145	1896-1901	VBN	denotes	known
T7146	1902-1904	TO	denotes	to
T7147	1905-1913	VB	denotes	interact
T7148	1914-1918	IN	denotes	with
T7149	1919-1924	NNP	denotes	Foxp3
T7150	1924-1925	-RRB-	denotes	)
T7151	1925-1926	.	denotes	.
T7152	1927-1938	RB	denotes	Furthermore
T7153	1938-1939	,	denotes	,
T7154	1940-1954	NN	denotes	overexpression
T7155	1955-1957	IN	denotes	of
T7156	1958-1962	NNP	denotes	ΔFKH
T7157	1963-1967	RB	denotes	also
T7158	1968-1971	VBD	denotes	led
T7159	1972-1974	TO	denotes	to
T7160	1975-1986	NN	denotes	suppression
T7161	1987-1989	IN	denotes	of
T7162	1990-1996	NNP	denotes	HTLV-I
T7163	1997-2012	NN	denotes	transactivation
T7164	2013-2015	IN	denotes	by
T7165	2016-2019	NNP	denotes	Tax
T7166	2020-2022	TO	denotes	to
T7167	2023-2024	DT	denotes	a
T7168	2025-2032	JJ	denotes	similar
T7169	2033-2039	NN	denotes	extent
T7170	2040-2042	IN	denotes	as
T7171	2043-2054	JJ	denotes	full-length
T7172	2055-2060	NNP	denotes	Foxp3
T7173	2061-2062	-LRB-	denotes	(
T7174	2062-2068	NNP	denotes	Figure
T7175	2069-2071	NNP	denotes	4B
T7176	2071-2072	-RRB-	denotes	)
T7177	2072-2073	.	denotes	.
T7178	2074-2077	DT	denotes	The
T7179	2078-2089	JJ	denotes	suppressive
T7180	2090-2097	NNS	denotes	effects
T7181	2098-2103	VBN	denotes	shown
T7182	2104-2106	IN	denotes	in
T7183	2107-2113	NN	denotes	Figure
T7184	2114-2116	CD	denotes	4A
T7185	2117-2120	CC	denotes	and
T7186	2121-2123	CD	denotes	4B
T7187	2124-2128	VBD	denotes	were
T7188	2129-2132	RB	denotes	not
T7189	2133-2136	DT	denotes	the
T7190	2137-2143	NN	denotes	result
T7191	2144-2146	IN	denotes	of
T7192	2147-2152	JJ	denotes	Foxp3
T7193	2153-2168	NN	denotes	down-regulating
T7194	2169-2172	DT	denotes	the
T7195	2173-2183	NN	denotes	expression
T7196	2184-2186	IN	denotes	of
T7197	2187-2190	DT	denotes	the
T7198	2191-2202	VBN	denotes	transfected
T7199	2203-2206	NNP	denotes	Tax
T7200	2207-2214	VBD	denotes	plasmid
T7201	2215-2217	IN	denotes	as
T7202	2218-2228	VBN	denotes	determined
T7203	2229-2231	IN	denotes	by
T7204	2232-2241	JJ	denotes	real-time
T7205	2242-2248	NNP	denotes	RT-PCR
T7206	2249-2250	-LRB-	denotes	(
T7207	2250-2256	NNP	denotes	Figure
T7208	2257-2259	NNP	denotes	4C
T7209	2259-2260	-RRB-	denotes	)
T7210	2260-2261	.	denotes	.
T7211	2262-2267	DT	denotes	These
T7212	2268-2275	NNS	denotes	results
T7213	2276-2284	RB	denotes	strongly
T7214	2285-2292	VBP	denotes	suggest
T7215	2293-2297	IN	denotes	that
T7216	2298-2303	JJ	denotes	Foxp3
T7217	2304-2313	NNS	denotes	interacts
T7218	2314-2318	IN	denotes	with
T7219	2319-2334	JJ	denotes	transcriptional
T7220	2335-2345	NNS	denotes	regulators
T7221	2346-2348	IN	denotes	in
T7222	2349-2357	NN	denotes	addition
T7223	2358-2360	TO	denotes	to
T7224	2361-2366	NNP	denotes	NF-κB
T7225	2367-2370	CC	denotes	and
T7226	2371-2376	NNP	denotes	NF-AT
T7227	2376-2377	,	denotes	,
T7228	2378-2381	CC	denotes	and
T7229	2382-2386	IN	denotes	that
T7230	2387-2390	DT	denotes	the
T7231	2391-2408	JJ	denotes	carboxyl-terminal
T7232	2409-2412	NNP	denotes	FKH
T7233	2413-2419	NN	denotes	domain
T7234	2419-2420	,	denotes	,
T7235	2421-2424	CC	denotes	and
T7236	2425-2434	RB	denotes	therefore
T7237	2435-2447	NN	denotes	localization
T7238	2448-2450	TO	denotes	to
T7239	2451-2454	DT	denotes	the
T7240	2455-2462	NN	denotes	nucleus
T7241	2462-2463	,	denotes	,
T7242	2464-2467	VBP	denotes	are
T7243	2468-2471	RB	denotes	not
T7244	2472-2480	VBN	denotes	required
T7245	2481-2484	IN	denotes	for
T7246	2485-2495	NN	denotes	inhibition
T7247	2496-2498	IN	denotes	of
T7248	2499-2511	JJ	denotes	Tax-mediated
T7249	2512-2518	NNP	denotes	HTLV-I
T7250	2519-2522	NNP	denotes	LTR
T7251	2523-2533	NN	denotes	activation
T7252	2534-2535	-LRB-	denotes	(
T7253	2535-2539	RB	denotes	even
T7254	2540-2542	IN	denotes	in
T7255	2543-2546	NNP	denotes	HEK
T7256	2547-2551	CD	denotes	293T
T7257	2552-2557	NNS	denotes	cells
T7258	2557-2558	-RRB-	denotes	)
T7259	2558-2559	.	denotes	.
T7260	3839-3841	TO	denotes	To
T7261	3842-3851	VB	denotes	determine
T7262	3852-3859	IN	denotes	whether
T7263	3860-3865	JJ	denotes	Foxp3
T7264	3866-3875	VBD	denotes	inhibited
T7265	3876-3879	DT	denotes	the
T7266	3880-3895	NN	denotes	transactivation
T7267	3896-3905	NNS	denotes	functions
T7268	3906-3908	IN	denotes	of
T7269	3909-3912	NNP	denotes	Tax
T7270	3913-3915	IN	denotes	by
T7271	3916-3924	RB	denotes	directly
T7272	3925-3936	VBG	denotes	associating
T7273	3937-3941	IN	denotes	with
T7274	3942-3946	DT	denotes	this
T7275	3947-3952	JJ	denotes	viral
T7276	3953-3960	NN	denotes	protein
T7277	3960-3961	,	denotes	,
T7278	3962-3964	PRP	denotes	we
T7279	3965-3974	VBD	denotes	generated
T7280	3975-3977	DT	denotes	an
T7281	3978-3988	NN	denotes	expression
T7282	3989-3995	NN	denotes	vector
T7283	3996-3998	IN	denotes	in
T7284	3999-4004	WDT	denotes	which
T7285	4005-4011	NNP	denotes	HTLV-I
T7286	4012-4015	NNP	denotes	Tax
T7287	4016-4019	VBD	denotes	was
T7288	4020-4025	VBN	denotes	fused
T7289	4026-4034	JJ	denotes	in-frame
T7290	4035-4037	TO	denotes	to
T7291	4038-4041	DT	denotes	the
T7292	4042-4050	NN	denotes	carboxyl
T7293	4051-4059	NN	denotes	terminus
T7294	4060-4062	IN	denotes	of
T7295	4063-4066	DT	denotes	the
T7296	4067-4071	NNP	denotes	Gal4
T7297	4072-4083	NNP	denotes	DNA-binding
T7298	4084-4090	NN	denotes	domain
T7299	4091-4092	-LRB-	denotes	(
T7300	4092-4099	JJ	denotes	Gal4-BD
T7301	4099-4100	-RRB-	denotes	)
T7302	4100-4101	.	denotes	.
T7303	4102-4106	DT	denotes	This
T7304	4107-4118	JJ	denotes	Gal4-BD-Tax
T7305	4119-4125	NN	denotes	fusion
T7306	4126-4133	NN	denotes	protein
T7307	4134-4143	VBD	denotes	activated
T7308	4144-4157	NN	denotes	transcription
T7309	4158-4160	IN	denotes	of
T7310	4161-4162	DT	denotes	a
T7311	4163-4172	JJ	denotes	synthetic
T7312	4173-4181	NN	denotes	promoter
T7313	4182-4192	VBG	denotes	containing
T7314	4193-4197	CD	denotes	five
T7315	4198-4202	JJ	denotes	Gal4
T7316	4203-4210	JJ	denotes	binding
T7317	4211-4216	NNS	denotes	sites
T7318	4216-4217	,	denotes	,
T7319	4218-4223	IN	denotes	while
T7320	4224-4231	NNP	denotes	Gal4-BD
T7321	4232-4235	VBD	denotes	was
T7322	4236-4248	JJ	denotes	insufficient
T7323	4249-4251	TO	denotes	to
T7324	4252-4261	VB	denotes	stimulate
T7325	4262-4275	NN	denotes	transcription
T7326	4276-4278	IN	denotes	by
T7327	4279-4285	PRP	denotes	itself
T7328	4286-4287	-LRB-	denotes	(
T7329	4287-4293	NN	denotes	Figure
T7330	4294-4296	CD	denotes	4D
T7331	4296-4297	-RRB-	denotes	)
T7332	4297-4298	.	denotes	.
T7333	4299-4314	NNP	denotes	Transactivation
T7334	4315-4317	IN	denotes	of
T7335	4318-4321	DT	denotes	the
T7336	4322-4336	JJ	denotes	Gal4-resposive
T7337	4337-4345	NN	denotes	promoter
T7338	4346-4348	IN	denotes	by
T7339	4349-4360	JJ	denotes	Gal4-BD-Tax
T7340	4361-4369	VBD	denotes	remained
T7341	4370-4380	RB	denotes	relatively
T7342	4381-4391	JJ	denotes	unaffected
T7343	4392-4394	IN	denotes	by
T7344	4395-4409	NN	denotes	overexpression
T7345	4410-4412	IN	denotes	of
T7346	4413-4419	DT	denotes	either
T7347	4420-4424	NNP	denotes	EGFP
T7348	4425-4426	-LRB-	denotes	(
T7349	4426-4433	NN	denotes	control
T7350	4433-4434	-RRB-	denotes	)
T7351	4434-4435	,	denotes	,
T7352	4436-4441	NNP	denotes	Foxp3
T7353	4441-4442	,	denotes	,
T7354	4443-4445	CC	denotes	or
T7355	4446-4450	NNP	denotes	ΔFKH
T7356	4450-4451	,	denotes	,
T7357	4452-4462	VBG	denotes	suggesting
T7358	4463-4467	IN	denotes	that
T7359	4468-4473	NNP	denotes	Foxp3
T7360	4474-4478	VBZ	denotes	does
T7361	4479-4482	RB	denotes	not
T7362	4483-4490	VB	denotes	repress
T7363	4491-4494	NNP	denotes	Tax
T7364	4495-4510	NN	denotes	transactivation
T7365	4511-4513	IN	denotes	by
T7366	4514-4522	RB	denotes	directly
T7367	4523-4534	VBG	denotes	interfacing
T7368	4535-4539	IN	denotes	with
T7369	4540-4543	DT	denotes	the
T7370	4544-4550	NNP	denotes	HTLV-I
T7371	4551-4554	NNP	denotes	Tax
T7372	4555-4562	NN	denotes	protein
T7373	4562-4563	.	denotes	.
T7374	4564-4566	TO	denotes	To
T7375	4567-4574	VB	denotes	confirm
T7376	4575-4579	IN	denotes	that
T7377	4580-4585	NNP	denotes	Foxp3
T7378	4586-4589	VBD	denotes	had
T7379	4590-4591	DT	denotes	a
T7380	4592-4598	JJ	denotes	direct
T7381	4599-4605	NN	denotes	effect
T7382	4606-4608	IN	denotes	on
T7383	4609-4615	NNP	denotes	HTLV-I
T7384	4616-4627	NN	denotes	replication
T7385	4627-4628	,	denotes	,
T7386	4629-4631	PRP	denotes	we
T7387	4632-4643	VBD	denotes	transfected
T7388	4644-4647	NNP	denotes	HEK
T7389	4648-4652	NNP	denotes	293T
T7390	4653-4658	NNS	denotes	cells
T7391	4659-4663	IN	denotes	with
T7392	4664-4665	DT	denotes	a
T7393	4666-4684	JJ	denotes	well-characterized
T7394	4685-4691	NNP	denotes	HTLV-I
T7395	4692-4702	JJ	denotes	infectious
T7396	4703-4712	JJ	denotes	molecular
T7397	4713-4718	NN	denotes	clone
T7398	4719-4720	-LRB-	denotes	(
T7399	4720-4726	VBN	denotes	termed
T7400	4727-4730	NNP	denotes	ACH
T7401	4730-4731	-RRB-	denotes	)
T7402	4732-4733	NNP	denotes	[
T7403	4733-4735	CD	denotes	30
T7404	4735-4736	NNP	denotes	]
T7405	4737-4739	IN	denotes	in
T7406	4740-4743	DT	denotes	the
T7407	4744-4752	NN	denotes	presence
T7408	4753-4755	IN	denotes	of
T7409	4756-4767	JJ	denotes	full-length
T7410	4768-4773	NNP	denotes	Foxp3
T7411	4773-4774	,	denotes	,
T7412	4775-4779	NNP	denotes	ΔFKH
T7413	4779-4780	,	denotes	,
T7414	4781-4783	CC	denotes	or
T7415	4784-4791	NN	denotes	control
T7416	4792-4798	NN	denotes	vector
T7417	4798-4799	.	denotes	.
T7418	4800-4803	NNP	denotes	ACH
T7419	4804-4807	VBZ	denotes	has
T7420	4808-4812	VBN	denotes	been
T7421	4813-4823	RB	denotes	previously
T7422	4824-4829	VBN	denotes	shown
T7423	4830-4832	TO	denotes	to
T7424	4833-4839	VB	denotes	direct
T7425	4840-4843	DT	denotes	the
T7426	4844-4854	NN	denotes	expression
T7427	4855-4857	IN	denotes	of
T7428	4858-4863	JJ	denotes	viral
T7429	4864-4872	NNS	denotes	antigens
T7430	4872-4873	,	denotes	,
T7431	4874-4881	VBP	denotes	produce
T7432	4882-4892	JJ	denotes	infectious
T7433	4893-4898	NN	denotes	virus
T7434	4898-4899	,	denotes	,
T7435	4900-4903	CC	denotes	and
T7436	4904-4913	VB	denotes	transform
T7437	4914-4917	NNP	denotes	CD4
T7438	4917-4918	CD	denotes	+
T7439	4919-4920	NNP	denotes	T
T7440	4921-4926	NNS	denotes	cells
T7441	4927-4931	DT	denotes	both
T7442	4932-4934	IN	denotes	in
T7443	4935-4940	NN	denotes	vitro
T7444	4941-4944	CC	denotes	and
T7445	4945-4947	IN	denotes	in
T7446	4948-4952	NN	denotes	vivo
T7447	4953-4954	NNP	denotes	[
T7448	4954-4959	CD	denotes	31,32
T7449	4959-4960	NNP	denotes	]
T7450	4960-4961	.	denotes	.
T7451	4962-4967	IN	denotes	After
T7452	4968-4970	CD	denotes	24
T7453	4971-4972	NN	denotes	h
T7454	4972-4973	,	denotes	,
T7455	4974-4977	DT	denotes	the
T7456	4978-4984	NN	denotes	amount
T7457	4985-4987	IN	denotes	of
T7458	4988-4993	JJ	denotes	viral
T7459	4994-5001	NN	denotes	antigen
T7460	5002-5012	NN	denotes	expression
T7461	5012-5013	,	denotes	,
T7462	5014-5016	IN	denotes	in
T7463	5017-5021	DT	denotes	this
T7464	5022-5026	NN	denotes	case
T7465	5027-5030	NNP	denotes	Tax
T7466	5031-5035	NNP	denotes	mRNA
T7467	5035-5036	,	denotes	,
T7468	5037-5040	VBD	denotes	was
T7469	5041-5049	VBN	denotes	detected
T7470	5050-5052	IN	denotes	by
T7471	5053-5054	DT	denotes	a
T7472	5055-5064	JJ	denotes	sensitive
T7473	5065-5074	JJ	denotes	real-time
T7474	5075-5081	NN	denotes	RT-PCR
T7475	5082-5087	NN	denotes	assay
T7476	5087-5088	.	denotes	.
T7477	5089-5091	IN	denotes	As
T7478	5092-5103	VBN	denotes	illustrated
T7479	5104-5106	IN	denotes	in
T7480	5107-5113	NN	denotes	Figure
T7481	5114-5115	CD	denotes	5
T7482	5115-5116	,	denotes	,
T7483	5117-5120	DT	denotes	the
T7484	5121-5126	NN	denotes	level
T7485	5127-5129	IN	denotes	of
T7486	5130-5133	NNP	denotes	Tax
T7487	5134-5138	NNP	denotes	mRNA
T7488	5139-5150	VBD	denotes	synthesized
T7489	5151-5155	IN	denotes	from
T7490	5156-5159	NNP	denotes	ACH
T7491	5160-5163	VBD	denotes	was
T7492	5164-5178	VBN	denotes	down-regulated
T7493	5179-5181	IN	denotes	in
T7494	5182-5185	DT	denotes	the
T7495	5186-5194	NN	denotes	presence
T7496	5195-5197	IN	denotes	of
T7497	5198-5203	JJ	denotes	Foxp3
T7498	5204-5212	VBN	denotes	compared
T7499	5213-5215	TO	denotes	to
T7500	5216-5219	DT	denotes	the
T7501	5220-5225	NN	denotes	level
T7502	5226-5234	VBN	denotes	produced
T7503	5235-5237	IN	denotes	in
T7504	5238-5241	DT	denotes	the
T7505	5242-5250	NN	denotes	presence
T7506	5251-5253	IN	denotes	of
T7507	5254-5257	DT	denotes	the
T7508	5258-5265	NN	denotes	control
T7509	5266-5272	NN	denotes	vector
T7510	5272-5273	.	denotes	.
T7511	5274-5278	NNP	denotes	ΔFKH
T7512	5279-5282	VBD	denotes	did
T7513	5283-5286	RB	denotes	not
T7514	5287-5291	VB	denotes	have
T7515	5292-5293	DT	denotes	a
T7516	5294-5305	JJ	denotes	discernable
T7517	5306-5312	VB	denotes	affect
T7518	5313-5315	IN	denotes	on
T7519	5316-5319	NNP	denotes	Tax
T7520	5320-5330	NN	denotes	expression
T7521	5330-5331	.	denotes	.
T7522	5332-5337	DT	denotes	These
T7523	5338-5342	NNS	denotes	data
T7524	5343-5351	VBP	denotes	indicate
T7525	5352-5356	IN	denotes	that
T7526	5357-5362	NNP	denotes	Foxp3
T7527	5363-5365	VBZ	denotes	is
T7528	5366-5373	JJ	denotes	capable
T7529	5374-5376	IN	denotes	of
T7530	5377-5387	VBG	denotes	repressing
T7531	5388-5391	DT	denotes	the
T7532	5392-5402	NN	denotes	expression
T7533	5403-5405	IN	denotes	of
T7534	5406-5409	NNP	denotes	Tax
T7535	5410-5414	IN	denotes	from
T7536	5415-5417	DT	denotes	an
T7537	5418-5428	JJ	denotes	infectious
T7538	5429-5435	NNP	denotes	HTLV-I
T7539	5436-5445	JJ	denotes	molecular
T7540	5446-5451	NN	denotes	clone
T7541	5451-5452	.	denotes	.
R5180	T6834	T6836	det	The,Functions
R5181	T6835	T6836	compound	Transactivation,Functions
R5182	T6836	T6841	nsubjpass	Functions,Suppressed
R5183	T6837	T6836	prep	of,Functions
R5184	T6838	T6839	compound	HTLV-I,Tax
R5185	T6839	T6837	pobj	Tax,of
R5186	T6840	T6841	auxpass	Are,Suppressed
R5187	T6841	T6841	ROOT	Suppressed,Suppressed
R5188	T6842	T6841	agent	by,Suppressed
R5189	T6843	T6842	pobj	Foxp3,by
R5190	T6844	T6845	amod	Previous,studies
R5191	T6845	T6842	pobj	studies,by
R5192	T6846	T6841	agent	by,Suppressed
R5193	T6847	T6846	pobj	Bettelli,by
R5194	T6848	T6847	cc	and,Bettelli
R5195	T6849	T6847	conj	colleagues,Bettelli
R5196	T6850	T6851	aux	have,demonstrated
R5197	T6851	T6841	conj	demonstrated,Suppressed
R5198	T6852	T6855	mark	that,repress
R5199	T6853	T6855	nsubj	Foxp3,repress
R5200	T6854	T6855	aux	can,repress
R5201	T6855	T6851	ccomp	repress,demonstrated
R5202	T6856	T6859	predet	both,levels
R5203	T6857	T6859	det	the,levels
R5204	T6858	T6859	amod	basal,levels
R5205	T6859	T6855	dobj	levels,repress
R5206	T6860	T6859	prep	of,levels
R5207	T6861	T6862	amod	NF-κB,activation
R5208	T6862	T6860	pobj	activation,of
R5209	T6863	T6865	advmod	as,as
R5210	T6864	T6865	advmod	well,as
R5211	T6865	T6862	cc	as,activation
R5212	T6866	T6867	compound	tumor,necrosis
R5213	T6867	T6870	nmod	necrosis,activation
R5214	T6868	T6870	amod	factor-α-stimulated,activation
R5215	T6869	T6870	compound	NF-κB,activation
R5216	T6870	T6862	conj	activation,activation
R5217	T6871	T6873	nmod	[,]
R5218	T6872	T6873	nummod	15,]
R5219	T6873	T6870	appos	],activation
R5220	T6874	T6841	punct	.,Suppressed
R5221	T6875	T6877	poss	Our,step
R5222	T6876	T6877	amod	next,step
R5223	T6877	T6878	nsubj	step,was
R5224	T6878	T6878	ROOT	was,was
R5225	T6879	T6880	aux	to,determine
R5226	T6880	T6878	xcomp	determine,was
R5227	T6881	T6885	mark	whether,suppress
R5228	T6882	T6885	nsubj	Foxp3,suppress
R5229	T6883	T6885	aux	could,suppress
R5230	T6884	T6885	advmod	also,suppress
R5231	T6885	T6880	ccomp	suppress,determine
R5232	T6886	T6887	det	the,activation
R5233	T6887	T6885	dobj	activation,suppress
R5234	T6888	T6887	prep	of,activation
R5235	T6889	T6888	pobj	NF-κB,of
R5236	T6890	T6887	acl	caused,activation
R5237	T6891	T6890	agent	by,caused
R5238	T6892	T6896	det	a,protein
R5239	T6893	T6896	amod	strong,protein
R5240	T6894	T6896	amod	viral,protein
R5241	T6895	T6896	compound	transactivator,protein
R5242	T6896	T6891	pobj	protein,by
R5243	T6897	T6878	punct	.,was
R5244	T6898	T6899	nsubj	HTLV-I,encodes
R5245	T6899	T6899	ROOT	encodes,encodes
R5246	T6900	T6903	det	a,protein
R5247	T6901	T6903	amod	multifunctional,protein
R5248	T6902	T6903	compound	transactivator,protein
R5249	T6903	T6899	dobj	protein,encodes
R5250	T6904	T6903	punct	",",protein
R5251	T6905	T6903	appos	Tax,protein
R5252	T6906	T6903	punct	",",protein
R5253	T6907	T6903	amod	capable,protein
R5254	T6908	T6907	prep	of,capable
R5255	T6909	T6908	pcomp	activating,of
R5256	T6910	T6912	preconj	both,NF-κB
R5257	T6911	T6912	det	the,NF-κB
R5258	T6912	T6915	nmod	NF-κB,pathways
R5259	T6913	T6912	cc	and,NF-κB
R5260	T6914	T6912	conj	CREB,NF-κB
R5261	T6915	T6909	dobj	pathways,activating
R5262	T6916	T6915	appos	[,pathways
R5263	T6917	T6916	nummod	24,[
R5264	T6918	T6919	nummod	29,]
R5265	T6919	T6916	appos	],[
R5266	T6920	T6899	punct	.,encodes
R5267	T6921	T6927	mark	Since,function
R5268	T6922	T6925	det	the,protein
R5269	T6923	T6924	compound	HTLV-I,Tax
R5270	T6924	T6925	compound	Tax,protein
R5271	T6925	T6927	nsubj	protein,function
R5272	T6926	T6927	aux	can,function
R5273	T6927	T6948	advcl	function,hypothesized
R5274	T6928	T6927	prep	at,function
R5275	T6929	T6930	amod	multiple,levels
R5276	T6930	T6928	pobj	levels,at
R5277	T6931	T6930	prep	in,levels
R5278	T6932	T6934	preconj	both,cytoplasm
R5279	T6933	T6934	det	the,cytoplasm
R5280	T6934	T6931	pobj	cytoplasm,in
R5281	T6935	T6934	cc	and,cytoplasm
R5282	T6936	T6937	det	the,nucleus
R5283	T6937	T6934	conj	nucleus,cytoplasm
R5284	T6938	T6939	aux	to,stimulate
R5285	T6939	T6937	acl	stimulate,nucleus
R5286	T6940	T6939	dobj	activation,stimulate
R5287	T6941	T6940	prep	of,activation
R5288	T6942	T6943	compound	NF-κB,[
R5289	T6943	T6945	compound	[,]
R5290	T6944	T6945	compound	"28,29",]
R5291	T6945	T6941	pobj	],of
R5292	T6946	T6948	punct	",",hypothesized
R5293	T6947	T6948	nsubj	we,hypothesized
R5294	T6948	T6948	ROOT	hypothesized,hypothesized
R5295	T6949	T6954	mark	that,interfere
R5296	T6950	T6954	nsubj	overexpression,interfere
R5297	T6951	T6950	prep	of,overexpression
R5298	T6952	T6951	pobj	Foxp3,of
R5299	T6953	T6954	aux	may,interfere
R5300	T6954	T6948	ccomp	interfere,hypothesized
R5301	T6955	T6954	prep	with,interfere
R5302	T6956	T6957	det	this,process
R5303	T6957	T6955	pobj	process,with
R5304	T6958	T6948	punct	.,hypothesized
R5305	T6959	T6976	advmod	However,hypothesized
R5306	T6960	T6976	punct	",",hypothesized
R5307	T6961	T6966	mark	since,is
R5308	T6962	T6965	amod	Tax-dependent,expression
R5309	T6963	T6964	compound	HTLV-I,gene
R5310	T6964	T6965	compound	gene,expression
R5311	T6965	T6966	nsubj	expression,is
R5312	T6966	T6976	advcl	is,hypothesized
R5313	T6967	T6966	acomp	independent,is
R5314	T6968	T6967	prep	of,independent
R5315	T6969	T6970	compound	NF-κB,[
R5316	T6970	T6968	pobj	[,of
R5317	T6971	T6972	nummod	18,]
R5318	T6972	T6976	npadvmod	],hypothesized
R5319	T6973	T6976	punct	",",hypothesized
R5320	T6974	T6976	nsubj	we,hypothesized
R5321	T6975	T6976	advmod	also,hypothesized
R5322	T6976	T6976	ROOT	hypothesized,hypothesized
R5323	T6977	T6981	mark	that,affect
R5324	T6978	T6981	nsubj	Foxp3,affect
R5325	T6979	T6981	aux	would,affect
R5326	T6980	T6981	neg	not,affect
R5327	T6981	T6976	ccomp	affect,hypothesized
R5328	T6982	T6983	amod	Tax-dependent,activation
R5329	T6983	T6981	dobj	activation,affect
R5330	T6984	T6983	prep	of,activation
R5331	T6985	T6987	det	the,LTR
R5332	T6986	T6987	compound	HTLV-I,LTR
R5333	T6987	T6984	pobj	LTR,of
R5334	T6988	T6976	punct	.,hypothesized
R5335	T6989	T6990	aux	To,test
R5336	T6990	T6995	advcl	test,overexpressed
R5337	T6991	T6992	det	these,hypotheses
R5338	T6992	T6990	dobj	hypotheses,test
R5339	T6993	T6995	punct	",",overexpressed
R5340	T6994	T6995	nsubj	we,overexpressed
R5341	T6995	T6995	ROOT	overexpressed,overexpressed
R5342	T6996	T6997	compound	HTLV-I,Tax
R5343	T6997	T6995	dobj	Tax,overexpressed
R5344	T6998	T6997	punct	",",Tax
R5345	T6999	T7000	amod	full-length,Foxp3
R5346	T7000	T6997	conj	Foxp3,Tax
R5347	T7001	T7000	punct	",",Foxp3
R5348	T7002	T7000	cc	and/or,Foxp3
R5349	T7003	T7000	conj	ΔFKH,Foxp3
R5350	T7004	T6995	prep	in,overexpressed
R5351	T7005	T7004	pobj	HEK,in
R5352	T7006	T7007	nummod	293T,cells
R5353	T7007	T6995	conj	cells,overexpressed
R5354	T7008	T7007	acl	cotransfected,cells
R5355	T7009	T7008	prep	with,cotransfected
R5356	T7010	T7012	det	an,LTR
R5357	T7011	T7012	compound	HTLV-I,LTR
R5358	T7012	T7009	pobj	LTR,with
R5359	T7013	T7012	cc	or,LTR
R5360	T7014	T7015	compound	NF-κB,reporter
R5361	T7015	T7016	compound	reporter,vector
R5362	T7016	T7012	conj	vector,LTR
R5363	T7017	T6995	punct	.,overexpressed
R5364	T7018	T7019	mark	As,shown
R5365	T7019	T7019	ROOT	shown,shown
R5366	T7020	T7019	prep	in,shown
R5367	T7021	T7020	pobj	Figure,in
R5368	T7022	T7021	nummod	4A,Figure
R5369	T7023	T7021	punct	",",Figure
R5370	T7024	T7025	compound	HTLV-I,Tax
R5371	T7025	T7030	nmod	Tax,activation
R5372	T7026	T7027	advmod	strongly,up-regulated
R5373	T7027	T7030	amod	up-regulated,activation
R5374	T7028	T7030	nmod	NF-κB-dependent,activation
R5375	T7029	T7030	amod	transcriptional,activation
R5376	T7030	T7021	conj	activation,Figure
R5377	T7031	T7030	punct	(,activation
R5378	T7032	T7033	nmod	~,60-fold
R5379	T7033	T7030	appos	60-fold,activation
R5380	T7034	T7033	punct	),60-fold
R5381	T7035	T7019	punct	.,shown
R5382	T7036	T7046	advmod	Interestingly,suppressed
R5383	T7037	T7046	punct	",",suppressed
R5384	T7038	T7046	nsubj	overexpression,suppressed
R5385	T7039	T7038	prep	of,overexpression
R5386	T7040	T7039	pobj	Foxp3,of
R5387	T7041	T7038	punct	",",overexpression
R5388	T7042	T7038	cc	but,overexpression
R5389	T7043	T7044	neg	not,ΔFKH
R5390	T7044	T7038	conj	ΔFKH,overexpression
R5391	T7045	T7044	punct	",",ΔFKH
R5392	T7046	T7046	ROOT	suppressed,suppressed
R5393	T7047	T7048	amod	Tax-mediated,activation
R5394	T7048	T7046	dobj	activation,suppressed
R5395	T7049	T7048	prep	of,activation
R5396	T7050	T7051	amod	NF-κB-dependent,transcription
R5397	T7051	T7049	pobj	transcription,of
R5398	T7052	T7046	punct	.,suppressed
R5399	T7053	T7054	det	These,observations
R5400	T7054	T7056	nsubj	observations,suggest
R5401	T7055	T7056	advmod	further,suggest
R5402	T7056	T7056	ROOT	suggest,suggest
R5403	T7057	T7063	mark	that,required
R5404	T7058	T7061	det	the,domain
R5405	T7059	T7061	amod	carboxyl-terminal,domain
R5406	T7060	T7061	compound	FKH,domain
R5407	T7061	T7063	nsubjpass	domain,required
R5408	T7062	T7063	auxpass	is,required
R5409	T7063	T7056	ccomp	required,suggest
R5410	T7064	T7063	prep	for,required
R5411	T7065	T7064	pcomp	inhibiting,for
R5412	T7066	T7065	dobj	activation,inhibiting
R5413	T7067	T7066	prep	of,activation
R5414	T7068	T7067	pobj	NF-κB,of
R5415	T7069	T7065	prep	in,inhibiting
R5416	T7070	T7071	det	the,presence
R5417	T7071	T7069	pobj	presence,in
R5418	T7072	T7071	prep	of,presence
R5419	T7073	T7072	pobj	Tax,of
R5420	T7074	T7071	prep	in,presence
R5421	T7075	T7074	pobj	HEK,in
R5422	T7076	T7077	nummod	293T,cells
R5423	T7077	T7065	dobj	cells,inhibiting
R5424	T7078	T7065	punct	",",inhibiting
R5425	T7079	T7080	advmod	strikingly,similar
R5426	T7080	T7063	conj	similar,required
R5427	T7081	T7080	prep	to,similar
R5428	T7082	T7083	det	the,requirements
R5429	T7083	T7081	pobj	requirements,to
R5430	T7084	T7083	prep	of,requirements
R5431	T7085	T7086	amod	Foxp3,inhibition
R5432	T7086	T7084	pobj	inhibition,of
R5433	T7087	T7086	prep	of,inhibition
R5434	T7088	T7090	amod	basal,activation
R5435	T7089	T7090	compound	NF-κB,activation
R5436	T7090	T7087	pobj	activation,of
R5437	T7091	T7083	acl	shown,requirements
R5438	T7092	T7091	prep	in,shown
R5439	T7093	T7094	amod	Figure,2B
R5440	T7094	T7092	pobj	2B,in
R5441	T7095	T7056	punct	.,suggest
R5442	T7096	T7102	nsubjpass	Transactivation,stimulated
R5443	T7097	T7096	prep	of,Transactivation
R5444	T7098	T7100	det	the,LTR
R5445	T7099	T7100	compound	HTLV-I,LTR
R5446	T7100	T7097	pobj	LTR,of
R5447	T7101	T7102	auxpass	was,stimulated
R5448	T7102	T7102	ROOT	stimulated,stimulated
R5449	T7103	T7102	prep	about,stimulated
R5450	T7104	T7103	pobj	55-fold,about
R5451	T7105	T7102	agent	by,stimulated
R5452	T7106	T7105	pobj	overexpression,by
R5453	T7107	T7106	prep	of,overexpression
R5454	T7108	T7107	pobj	Tax,of
R5455	T7109	T7111	punct	(,4B
R5456	T7110	T7111	compound	Figure,4B
R5457	T7111	T7108	appos	4B,Tax
R5458	T7112	T7108	punct	),Tax
R5459	T7113	T7102	punct	",",stimulated
R5460	T7114	T7135	mark	while,is
R5461	T7115	T7135	advcl	transfection,is
R5462	T7116	T7115	prep	of,transfection
R5463	T7117	T7119	amod	Foxp3,Tax-dependent
R5464	T7118	T7119	amod	suppressed,Tax-dependent
R5465	T7119	T7121	compound	Tax-dependent,LTR
R5466	T7120	T7121	compound	HTLV-I,LTR
R5467	T7121	T7122	compound	LTR,activation
R5468	T7122	T7116	pobj	activation,of
R5469	T7123	T7135	punct	",",is
R5470	T7124	T7135	mark	although,is
R5471	T7125	T7126	compound	HTLV-I,LTR
R5472	T7126	T7127	compound	LTR,activation
R5473	T7127	T7135	nsubj	activation,is
R5474	T7128	T7127	prep	in,activation
R5475	T7129	T7130	det	the,presence
R5476	T7130	T7128	pobj	presence,in
R5477	T7131	T7130	cc	or,presence
R5478	T7132	T7130	conj	absence,presence
R5479	T7133	T7132	prep	of,absence
R5480	T7134	T7133	pobj	Tax,of
R5481	T7135	T7102	advcl	is,stimulated
R5482	T7136	T7135	acomp	independent,is
R5483	T7137	T7136	prep	of,independent
R5484	T7138	T7137	pobj	NF-κB,of
R5485	T7139	T7138	cc	or,NF-κB
R5486	T7140	T7138	conj	NF-AT,NF-κB
R5487	T7141	T7140	punct	(,NF-AT
R5488	T7142	T7143	det	another,transcriptional
R5489	T7143	T7144	compound	transcriptional,activator
R5490	T7144	T7140	appos	activator,NF-AT
R5491	T7145	T7144	acl	known,activator
R5492	T7146	T7147	aux	to,interact
R5493	T7147	T7145	xcomp	interact,known
R5494	T7148	T7147	prep	with,interact
R5495	T7149	T7148	pobj	Foxp3,with
R5496	T7150	T7140	punct	),NF-AT
R5497	T7151	T7102	punct	.,stimulated
R5498	T7152	T7158	advmod	Furthermore,led
R5499	T7153	T7158	punct	",",led
R5500	T7154	T7158	nsubj	overexpression,led
R5501	T7155	T7154	prep	of,overexpression
R5502	T7156	T7155	pobj	ΔFKH,of
R5503	T7157	T7158	advmod	also,led
R5504	T7158	T7158	ROOT	led,led
R5505	T7159	T7158	prep	to,led
R5506	T7160	T7159	pobj	suppression,to
R5507	T7161	T7160	prep	of,suppression
R5508	T7162	T7163	compound	HTLV-I,transactivation
R5509	T7163	T7161	pobj	transactivation,of
R5510	T7164	T7160	prep	by,suppression
R5511	T7165	T7164	pobj	Tax,by
R5512	T7166	T7158	prep	to,led
R5513	T7167	T7169	det	a,extent
R5514	T7168	T7169	amod	similar,extent
R5515	T7169	T7166	pobj	extent,to
R5516	T7170	T7158	prep	as,led
R5517	T7171	T7172	amod	full-length,Foxp3
R5518	T7172	T7170	pobj	Foxp3,as
R5519	T7173	T7175	punct	(,4B
R5520	T7174	T7175	compound	Figure,4B
R5521	T7175	T7172	appos	4B,Foxp3
R5522	T7176	T7175	punct	),4B
R5523	T7177	T7158	punct	.,led
R5524	T7178	T7180	det	The,effects
R5525	T7179	T7180	amod	suppressive,effects
R5526	T7180	T7187	nsubj	effects,were
R5527	T7181	T7180	acl	shown,effects
R5528	T7182	T7181	prep	in,shown
R5529	T7183	T7182	pobj	Figure,in
R5530	T7184	T7183	nummod	4A,Figure
R5531	T7185	T7183	cc	and,Figure
R5532	T7186	T7183	conj	4B,Figure
R5533	T7187	T7187	ROOT	were,were
R5534	T7188	T7187	neg	not,were
R5535	T7189	T7190	det	the,result
R5536	T7190	T7187	attr	result,were
R5537	T7191	T7190	prep	of,result
R5538	T7192	T7193	amod	Foxp3,down-regulating
R5539	T7193	T7191	pobj	down-regulating,of
R5540	T7194	T7195	det	the,expression
R5541	T7195	T7190	conj	expression,result
R5542	T7196	T7195	prep	of,expression
R5543	T7197	T7200	det	the,plasmid
R5544	T7198	T7199	compound	transfected,Tax
R5545	T7199	T7200	compound	Tax,plasmid
R5546	T7200	T7196	pobj	plasmid,of
R5547	T7201	T7202	mark	as,determined
R5548	T7202	T7187	advcl	determined,were
R5549	T7203	T7202	agent	by,determined
R5550	T7204	T7205	amod	real-time,RT-PCR
R5551	T7205	T7203	pobj	RT-PCR,by
R5552	T7206	T7208	punct	(,4C
R5553	T7207	T7208	compound	Figure,4C
R5554	T7208	T7205	appos	4C,RT-PCR
R5555	T7209	T7208	punct	),4C
R5556	T7210	T7187	punct	.,were
R5557	T7211	T7212	det	These,results
R5558	T7212	T7214	nsubj	results,suggest
R5559	T7213	T7214	advmod	strongly,suggest
R5560	T7214	T7214	ROOT	suggest,suggest
R5561	T7215	T7217	mark	that,interacts
R5562	T7216	T7217	nsubj	Foxp3,interacts
R5563	T7217	T7214	ccomp	interacts,suggest
R5564	T7218	T7217	prep	with,interacts
R5565	T7219	T7220	amod	transcriptional,regulators
R5566	T7220	T7218	pobj	regulators,with
R5567	T7221	T7217	prep	in,interacts
R5568	T7222	T7221	pobj	addition,in
R5569	T7223	T7222	prep	to,addition
R5570	T7224	T7223	pobj	NF-κB,to
R5571	T7225	T7224	cc	and,NF-κB
R5572	T7226	T7224	conj	NF-AT,NF-κB
R5573	T7227	T7226	punct	",",NF-AT
R5574	T7228	T7217	cc	and,interacts
R5575	T7229	T7244	mark	that,required
R5576	T7230	T7233	det	the,domain
R5577	T7231	T7233	amod	carboxyl-terminal,domain
R5578	T7232	T7233	compound	FKH,domain
R5579	T7233	T7244	nsubjpass	domain,required
R5580	T7234	T7233	punct	",",domain
R5581	T7235	T7233	cc	and,domain
R5582	T7236	T7237	advmod	therefore,localization
R5583	T7237	T7233	conj	localization,domain
R5584	T7238	T7233	prep	to,domain
R5585	T7239	T7240	det	the,nucleus
R5586	T7240	T7238	pobj	nucleus,to
R5587	T7241	T7244	punct	",",required
R5588	T7242	T7244	auxpass	are,required
R5589	T7243	T7244	neg	not,required
R5590	T7244	T7217	conj	required,interacts
R5591	T7245	T7244	prep	for,required
R5592	T7246	T7245	pobj	inhibition,for
R5593	T7247	T7246	prep	of,inhibition
R5594	T7248	T7251	amod	Tax-mediated,activation
R5595	T7249	T7250	compound	HTLV-I,LTR
R5596	T7250	T7251	compound	LTR,activation
R5597	T7251	T7247	pobj	activation,of
R5598	T7252	T7244	punct	(,required
R5599	T7253	T7254	advmod	even,in
R5600	T7254	T7244	prep	in,required
R5601	T7255	T7254	pobj	HEK,in
R5602	T7256	T7255	nummod	293T,HEK
R5603	T7257	T7244	conj	cells,required
R5604	T7258	T7214	punct	),suggest
R5605	T7259	T7214	punct	.,suggest
R5606	T7260	T7261	aux	To,determine
R5607	T7261	T7279	advcl	determine,generated
R5608	T7262	T7264	mark	whether,inhibited
R5609	T7263	T7264	nsubj	Foxp3,inhibited
R5610	T7264	T7279	advcl	inhibited,generated
R5611	T7265	T7267	det	the,functions
R5612	T7266	T7267	compound	transactivation,functions
R5613	T7267	T7264	dobj	functions,inhibited
R5614	T7268	T7267	prep	of,functions
R5615	T7269	T7268	pobj	Tax,of
R5616	T7270	T7264	prep	by,inhibited
R5617	T7271	T7272	advmod	directly,associating
R5618	T7272	T7270	pcomp	associating,by
R5619	T7273	T7272	prep	with,associating
R5620	T7274	T7276	det	this,protein
R5621	T7275	T7276	amod	viral,protein
R5622	T7276	T7273	pobj	protein,with
R5623	T7277	T7279	punct	",",generated
R5624	T7278	T7279	nsubj	we,generated
R5625	T7279	T7279	ROOT	generated,generated
R5626	T7280	T7282	det	an,vector
R5627	T7281	T7282	compound	expression,vector
R5628	T7282	T7279	dobj	vector,generated
R5629	T7283	T7288	prep	in,fused
R5630	T7284	T7283	pobj	which,in
R5631	T7285	T7286	compound	HTLV-I,Tax
R5632	T7286	T7288	nsubjpass	Tax,fused
R5633	T7287	T7288	auxpass	was,fused
R5634	T7288	T7282	relcl	fused,vector
R5635	T7289	T7288	oprd	in-frame,fused
R5636	T7290	T7289	prep	to,in-frame
R5637	T7291	T7293	det	the,terminus
R5638	T7292	T7293	compound	carboxyl,terminus
R5639	T7293	T7290	pobj	terminus,to
R5640	T7294	T7293	prep	of,terminus
R5641	T7295	T7298	det	the,domain
R5642	T7296	T7298	compound	Gal4,domain
R5643	T7297	T7298	compound	DNA-binding,domain
R5644	T7298	T7294	pobj	domain,of
R5645	T7299	T7300	punct	(,Gal4-BD
R5646	T7300	T7298	appos	Gal4-BD,domain
R5647	T7301	T7300	punct	),Gal4-BD
R5648	T7302	T7279	punct	.,generated
R5649	T7303	T7306	det	This,protein
R5650	T7304	T7306	amod	Gal4-BD-Tax,protein
R5651	T7305	T7306	compound	fusion,protein
R5652	T7306	T7307	nsubj	protein,activated
R5653	T7307	T7307	ROOT	activated,activated
R5654	T7308	T7307	dobj	transcription,activated
R5655	T7309	T7308	prep	of,transcription
R5656	T7310	T7312	det	a,promoter
R5657	T7311	T7312	amod	synthetic,promoter
R5658	T7312	T7309	pobj	promoter,of
R5659	T7313	T7312	acl	containing,promoter
R5660	T7314	T7317	nummod	five,sites
R5661	T7315	T7317	amod	Gal4,sites
R5662	T7316	T7317	amod	binding,sites
R5663	T7317	T7313	dobj	sites,containing
R5664	T7318	T7307	punct	",",activated
R5665	T7319	T7321	mark	while,was
R5666	T7320	T7321	nsubj	Gal4-BD,was
R5667	T7321	T7307	advcl	was,activated
R5668	T7322	T7321	acomp	insufficient,was
R5669	T7323	T7324	aux	to,stimulate
R5670	T7324	T7322	xcomp	stimulate,insufficient
R5671	T7325	T7324	dobj	transcription,stimulate
R5672	T7326	T7324	prep	by,stimulate
R5673	T7327	T7326	pobj	itself,by
R5674	T7328	T7329	punct	(,Figure
R5675	T7329	T7321	npadvmod	Figure,was
R5676	T7330	T7329	nummod	4D,Figure
R5677	T7331	T7329	punct	),Figure
R5678	T7332	T7307	punct	.,activated
R5679	T7333	T7340	nsubj	Transactivation,remained
R5680	T7334	T7333	prep	of,Transactivation
R5681	T7335	T7337	det	the,promoter
R5682	T7336	T7337	amod	Gal4-resposive,promoter
R5683	T7337	T7334	pobj	promoter,of
R5684	T7338	T7340	prep	by,remained
R5685	T7339	T7338	pobj	Gal4-BD-Tax,by
R5686	T7340	T7340	ROOT	remained,remained
R5687	T7341	T7342	advmod	relatively,unaffected
R5688	T7342	T7340	acomp	unaffected,remained
R5689	T7343	T7342	prep	by,unaffected
R5690	T7344	T7343	pobj	overexpression,by
R5691	T7345	T7344	prep	of,overexpression
R5692	T7346	T7347	det	either,EGFP
R5693	T7347	T7345	pobj	EGFP,of
R5694	T7348	T7347	punct	(,EGFP
R5695	T7349	T7347	appos	control,EGFP
R5696	T7350	T7347	punct	),EGFP
R5697	T7351	T7347	punct	",",EGFP
R5698	T7352	T7347	conj	Foxp3,EGFP
R5699	T7353	T7352	punct	",",Foxp3
R5700	T7354	T7352	cc	or,Foxp3
R5701	T7355	T7352	conj	ΔFKH,Foxp3
R5702	T7356	T7340	punct	",",remained
R5703	T7357	T7340	advcl	suggesting,remained
R5704	T7358	T7362	mark	that,repress
R5705	T7359	T7362	nsubj	Foxp3,repress
R5706	T7360	T7362	aux	does,repress
R5707	T7361	T7362	neg	not,repress
R5708	T7362	T7357	ccomp	repress,suggesting
R5709	T7363	T7364	compound	Tax,transactivation
R5710	T7364	T7362	dobj	transactivation,repress
R5711	T7365	T7362	prep	by,repress
R5712	T7366	T7367	advmod	directly,interfacing
R5713	T7367	T7365	pcomp	interfacing,by
R5714	T7368	T7367	prep	with,interfacing
R5715	T7369	T7372	det	the,protein
R5716	T7370	T7371	compound	HTLV-I,Tax
R5717	T7371	T7372	compound	Tax,protein
R5718	T7372	T7368	pobj	protein,with
R5719	T7373	T7340	punct	.,remained
R5720	T7374	T7375	aux	To,confirm
R5721	T7375	T7387	advcl	confirm,transfected
R5722	T7376	T7378	mark	that,had
R5723	T7377	T7378	nsubj	Foxp3,had
R5724	T7378	T7375	ccomp	had,confirm
R5725	T7379	T7381	det	a,effect
R5726	T7380	T7381	amod	direct,effect
R5727	T7381	T7378	dobj	effect,had
R5728	T7382	T7381	prep	on,effect
R5729	T7383	T7384	compound	HTLV-I,replication
R5730	T7384	T7382	pobj	replication,on
R5731	T7385	T7387	punct	",",transfected
R5732	T7386	T7387	nsubj	we,transfected
R5733	T7387	T7387	ROOT	transfected,transfected
R5734	T7388	T7389	compound	HEK,293T
R5735	T7389	T7390	compound	293T,cells
R5736	T7390	T7387	dobj	cells,transfected
R5737	T7391	T7387	prep	with,transfected
R5738	T7392	T7397	det	a,clone
R5739	T7393	T7397	amod	well-characterized,clone
R5740	T7394	T7397	nmod	HTLV-I,clone
R5741	T7395	T7397	amod	infectious,clone
R5742	T7396	T7397	amod	molecular,clone
R5743	T7397	T7391	pobj	clone,with
R5744	T7398	T7397	punct	(,clone
R5745	T7399	T7397	acl	termed,clone
R5746	T7400	T7399	oprd	ACH,termed
R5747	T7401	T7397	punct	),clone
R5748	T7402	T7404	nmod	[,]
R5749	T7403	T7404	nummod	30,]
R5750	T7404	T7404	ROOT	],]
R5751	T7405	T7404	prep	in,]
R5752	T7406	T7407	det	the,presence
R5753	T7407	T7405	pobj	presence,in
R5754	T7408	T7407	prep	of,presence
R5755	T7409	T7410	amod	full-length,Foxp3
R5756	T7410	T7408	pobj	Foxp3,of
R5757	T7411	T7410	punct	",",Foxp3
R5758	T7412	T7410	conj	ΔFKH,Foxp3
R5759	T7413	T7412	punct	",",ΔFKH
R5760	T7414	T7412	cc	or,ΔFKH
R5761	T7415	T7416	compound	control,vector
R5762	T7416	T7412	conj	vector,ΔFKH
R5763	T7417	T7387	punct	.,transfected
R5764	T7418	T7422	nsubjpass	ACH,shown
R5765	T7419	T7422	aux	has,shown
R5766	T7420	T7422	auxpass	been,shown
R5767	T7421	T7422	advmod	previously,shown
R5768	T7422	T7422	ROOT	shown,shown
R5769	T7423	T7424	aux	to,direct
R5770	T7424	T7422	xcomp	direct,shown
R5771	T7425	T7426	det	the,expression
R5772	T7426	T7424	dobj	expression,direct
R5773	T7427	T7426	prep	of,expression
R5774	T7428	T7429	amod	viral,antigens
R5775	T7429	T7427	pobj	antigens,of
R5776	T7430	T7431	punct	",",produce
R5777	T7431	T7422	conj	produce,shown
R5778	T7432	T7433	amod	infectious,virus
R5779	T7433	T7431	dobj	virus,produce
R5780	T7434	T7431	punct	",",produce
R5781	T7435	T7431	cc	and,produce
R5782	T7436	T7431	conj	transform,produce
R5783	T7437	T7440	compound	CD4,cells
R5784	T7438	T7440	nummod	+,cells
R5785	T7439	T7440	compound	T,cells
R5786	T7440	T7436	dobj	cells,transform
R5787	T7441	T7442	preconj	both,in
R5788	T7442	T7436	prep	in,transform
R5789	T7443	T7442	pobj	vitro,in
R5790	T7444	T7442	cc	and,in
R5791	T7445	T7442	conj	in,in
R5792	T7446	T7445	pobj	vivo,in
R5793	T7447	T7449	compound	[,]
R5794	T7448	T7449	compound	"31,32",]
R5795	T7449	T7431	conj	],produce
R5796	T7450	T7422	punct	.,shown
R5797	T7451	T7451	ROOT	After,After
R5798	T7452	T7453	nummod	24,h
R5799	T7453	T7451	pobj	h,After
R5800	T7454	T7453	punct	",",h
R5801	T7455	T7456	det	the,amount
R5802	T7456	T7451	pobj	amount,After
R5803	T7457	T7456	prep	of,amount
R5804	T7458	T7460	amod	viral,expression
R5805	T7459	T7460	compound	antigen,expression
R5806	T7460	T7457	pobj	expression,of
R5807	T7461	T7456	punct	",",amount
R5808	T7462	T7469	prep	in,detected
R5809	T7463	T7464	det	this,case
R5810	T7464	T7462	pobj	case,in
R5811	T7465	T7466	compound	Tax,mRNA
R5812	T7466	T7462	pobj	mRNA,in
R5813	T7467	T7469	punct	",",detected
R5814	T7468	T7469	auxpass	was,detected
R5815	T7469	T7456	relcl	detected,amount
R5816	T7470	T7469	agent	by,detected
R5817	T7471	T7475	det	a,assay
R5818	T7472	T7475	amod	sensitive,assay
R5819	T7473	T7475	amod	real-time,assay
R5820	T7474	T7475	compound	RT-PCR,assay
R5821	T7475	T7470	pobj	assay,by
R5822	T7476	T7469	punct	.,detected
R5823	T7477	T7478	mark	As,illustrated
R5824	T7478	T7491	advcl	illustrated,was
R5825	T7479	T7478	prep	in,illustrated
R5826	T7480	T7479	pobj	Figure,in
R5827	T7481	T7480	nummod	5,Figure
R5828	T7482	T7480	punct	",",Figure
R5829	T7483	T7484	det	the,level
R5830	T7484	T7491	nsubj	level,was
R5831	T7485	T7484	prep	of,level
R5832	T7486	T7487	compound	Tax,mRNA
R5833	T7487	T7485	pobj	mRNA,of
R5834	T7488	T7484	acl	synthesized,level
R5835	T7489	T7488	prep	from,synthesized
R5836	T7490	T7489	pobj	ACH,from
R5837	T7491	T7491	ROOT	was,was
R5838	T7492	T7491	attr	down-regulated,was
R5839	T7493	T7492	prep	in,down-regulated
R5840	T7494	T7495	det	the,presence
R5841	T7495	T7493	pobj	presence,in
R5842	T7496	T7495	prep	of,presence
R5843	T7497	T7496	pobj	Foxp3,of
R5844	T7498	T7491	prep	compared,was
R5845	T7499	T7498	prep	to,compared
R5846	T7500	T7501	det	the,level
R5847	T7501	T7499	pobj	level,to
R5848	T7502	T7501	acl	produced,level
R5849	T7503	T7502	prep	in,produced
R5850	T7504	T7505	det	the,presence
R5851	T7505	T7503	pobj	presence,in
R5852	T7506	T7505	prep	of,presence
R5853	T7507	T7509	det	the,vector
R5854	T7508	T7509	compound	control,vector
R5855	T7509	T7506	pobj	vector,of
R5856	T7510	T7491	punct	.,was
R5857	T7511	T7514	nsubj	ΔFKH,have
R5858	T7512	T7514	aux	did,have
R5859	T7513	T7514	neg	not,have
R5860	T7514	T7514	ROOT	have,have
R5861	T7515	T7517	det	a,affect
R5862	T7516	T7517	amod	discernable,affect
R5863	T7517	T7514	dobj	affect,have
R5864	T7518	T7517	prep	on,affect
R5865	T7519	T7520	compound	Tax,expression
R5866	T7520	T7518	pobj	expression,on
R5867	T7521	T7514	punct	.,have
R5868	T7522	T7523	det	These,data
R5869	T7523	T7524	nsubj	data,indicate
R5870	T7524	T7524	ROOT	indicate,indicate
R5871	T7525	T7527	mark	that,is
R5872	T7526	T7527	nsubj	Foxp3,is
R5873	T7527	T7524	ccomp	is,indicate
R5874	T7528	T7527	acomp	capable,is
R5875	T7529	T7528	prep	of,capable
R5876	T7530	T7529	pcomp	repressing,of
R5877	T7531	T7532	det	the,expression
R5878	T7532	T7530	dobj	expression,repressing
R5879	T7533	T7532	prep	of,expression
R5880	T7534	T7533	pobj	Tax,of
R5881	T7535	T7530	prep	from,repressing
R5882	T7536	T7540	det	an,clone
R5883	T7537	T7540	amod	infectious,clone
R5884	T7538	T7540	nmod	HTLV-I,clone
R5885	T7539	T7540	amod	molecular,clone
R5886	T7540	T7535	pobj	clone,from
R5887	T7541	T7524	punct	.,indicate

GO-BP

Id	Subject	Object	Predicate	Lexical cue
T6810	4-19	http://purl.obolibrary.org/obo/GO_2000144	denotes	Transactivation
T6811	1586-1601	http://purl.obolibrary.org/obo/GO_2000144	denotes	Transactivation
T6812	4299-4314	http://purl.obolibrary.org/obo/GO_2000144	denotes	Transactivation
T6813	4495-4510	http://purl.obolibrary.org/obo/GO_2000144	denotes	transactivation
T6814	212-220	http://purl.obolibrary.org/obo/GO_0001906	denotes	necrosis
T6815	212-220	http://purl.obolibrary.org/obo/GO_0008219	denotes	necrosis
T6816	212-220	http://purl.obolibrary.org/obo/GO_0019835	denotes	necrosis
T6817	212-220	http://purl.obolibrary.org/obo/GO_0070265	denotes	necrosis
T6818	333-352	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of NF-κB
T6819	640-659	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of NF-κB
T6820	1274-1293	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of NF-κB
T6821	1419-1438	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of NF-κB
T6822	783-798	http://purl.obolibrary.org/obo/GO_0010467	denotes	gene expression
T6823	1147-1183	http://purl.obolibrary.org/obo/GO_1900622	denotes	dependent transcriptional activation
T6824	1147-1183	http://purl.obolibrary.org/obo/GO_0045893	denotes	dependent transcriptional activation
T6825	1157-1172	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcriptional
T6826	1870-1885	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcriptional
T6827	2319-2334	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcriptional
T6828	4144-4157	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T6829	4262-4275	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T6830	2242-2244	http://purl.obolibrary.org/obo/GO_0003964	denotes	RT
T6831	5075-5077	http://purl.obolibrary.org/obo/GO_0003964	denotes	RT
T6832	2435-2447	http://purl.obolibrary.org/obo/GO_0051179	denotes	localization
T6833	2435-2462	http://purl.obolibrary.org/obo/GO_0051647	denotes	localization to the nucleus

GO-MF

Id	Subject	Object	Predicate	Lexical cue
T8318	2242-2244	http://purl.obolibrary.org/obo/GO_0003964	denotes	RT
T8319	5075-5077	http://purl.obolibrary.org/obo/GO_0003964	denotes	RT
T8320	4072-4083	http://purl.obolibrary.org/obo/GO_0003677	denotes	DNA-binding
T8321	4072-4090	http://purl.obolibrary.org/obo/GO_0050692	denotes	DNA-binding domain
T8322	4076-4083	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T8323	4203-4210	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding

GO-CC

Id	Subject	Object	Predicate	Lexical cue
T8324	601-610	http://purl.obolibrary.org/obo/GO_0005737	denotes	cytoplasm
T8325	619-626	http://purl.obolibrary.org/obo/GO_0005634	denotes	nucleus
T8326	2455-2462	http://purl.obolibrary.org/obo/GO_0005634	denotes	nucleus
T8327	1020-1025	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T8328	1474-1479	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T8329	2552-2557	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T8330	4653-4658	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T8331	4921-4926	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells

events-check-again

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T8754	40-43	Protein	denotes	Tax
T8755	62-67	Protein	denotes	Foxp3
T8756	135-140	Protein	denotes	Foxp3
T8757	206-229	Protein	denotes	tumor necrosis factor-α
T8758	303-308	Protein	denotes	Foxp3
T8759	459-462	Protein	denotes	Tax
T8760	545-548	Protein	denotes	Tax
T8761	690-704	Positive_regulation	denotes	overexpression
T8762	708-713	Protein	denotes	Foxp3
T8763	762-765	Protein	denotes	Tax
T8764	855-860	Protein	denotes	Foxp3
T8765	878-881	Protein	denotes	Tax
T8766	951-964	Positive_regulation	denotes	overexpressed
T8767	951-964	Positive_regulation	denotes	overexpressed
T8768	951-964	Positive_regulation	denotes	overexpressed
T8769	972-975	Protein	denotes	Tax
T8770	989-994	Protein	denotes	Foxp3
T8771	1003-1007	Protein	denotes	ΔFKH
T8772	1115-1118	Protein	denotes	Tax
T8773	1211-1225	Gene_expression	denotes	overexpression
T8774	1211-1225	Gene_expression	denotes	overexpression
T8775	1229-1234	Protein	denotes	Foxp3
T8776	1244-1248	Protein	denotes	ΔFKH
T8777	1261-1264	Protein	denotes	Tax
T8778	1458-1461	Protein	denotes	Tax
T8779	1523-1528	Protein	denotes	Foxp3
T8780	1652-1666	Positive_regulation	denotes	overexpression
T8781	1670-1673	Protein	denotes	Tax
T8782	1693-1705	Gene_expression	denotes	transfection
T8783	1709-1714	Protein	denotes	Foxp3
T8784	1726-1729	Protein	denotes	Tax
T8785	1824-1827	Protein	denotes	Tax
T8786	1905-1913	Binding	denotes	interact
T8787	1919-1924	Protein	denotes	Foxp3
T8788	1940-1954	Positive_regulation	denotes	overexpression
T8789	1958-1962	Protein	denotes	ΔFKH
T8790	2016-2019	Protein	denotes	Tax
T8791	2055-2060	Protein	denotes	Foxp3
T8792	2147-2152	Protein	denotes	Foxp3
T8793	2153-2168	Negative_regulation	denotes	down-regulating
T8794	2173-2183	Gene_expression	denotes	expression
T8795	2203-2206	Protein	denotes	Tax
T8796	2298-2303	Protein	denotes	Foxp3
T8797	2304-2313	Binding	denotes	interacts		true
T8798	2435-2447	Localization	denotes	localization
T8799	2455-2462	Entity	denotes	nucleus
T8800	2499-2502	Protein	denotes	Tax
T8801	3860-3865	Protein	denotes	Foxp3
T8802	3909-3912	Protein	denotes	Tax
T8803	3925-3936	Binding	denotes	associating		true
T8804	4012-4015	Protein	denotes	Tax
T8805	4067-4071	Protein	denotes	Gal4
T8806	4092-4096	Protein	denotes	Gal4
T8807	4107-4118	Protein	denotes	Gal4-BD-Tax
T8808	4224-4228	Protein	denotes	Gal4
T8809	4349-4360	Protein	denotes	Gal4-BD-Tax
T8810	4395-4409	Positive_regulation	denotes	overexpression
T8811	4395-4409	Positive_regulation	denotes	overexpression
T8812	4436-4441	Protein	denotes	Foxp3
T8813	4446-4450	Protein	denotes	ΔFKH
T8814	4468-4473	Protein	denotes	Foxp3
T8815	4491-4494	Protein	denotes	Tax
T8816	4523-4534	Negative_regulation	denotes	interfacing
T8817	4551-4554	Protein	denotes	Tax
T8818	4580-4585	Protein	denotes	Foxp3
T8819	4768-4773	Protein	denotes	Foxp3
T8820	4775-4779	Protein	denotes	ΔFKH
T8821	4914-4917	Protein	denotes	CD4
T8822	5002-5012	Transcription	denotes	expression
T8823	5027-5030	Protein	denotes	Tax
T8824	5130-5133	Protein	denotes	Tax
T8825	5139-5150	Transcription	denotes	synthesized
T8826	5164-5178	Negative_regulation	denotes	down-regulated
T8827	5198-5203	Protein	denotes	Foxp3
T8828	5226-5234	Transcription	denotes	produced
T8829	5274-5278	Protein	denotes	ΔFKH
T8830	5306-5312	Regulation	denotes	affect	true
T8831	5316-5319	Protein	denotes	Tax
T8832	5320-5330	Gene_expression	denotes	expression
T8833	5357-5362	Protein	denotes	Foxp3
T8834	5377-5387	Negative_regulation	denotes	repressing
T8835	5392-5402	Gene_expression	denotes	expression
T8836	5406-5409	Protein	denotes	Tax
R6724	T8762	T8761	themeOf	Foxp3,overexpression
R6729	T8769	T8768	themeOf	Tax,overexpressed
R6733	T8770	T8767	themeOf	Foxp3,overexpressed
R6736	T8771	T8766	themeOf	ΔFKH,overexpressed
R6739	T8775	T8774	themeOf	Foxp3,overexpression
R6743	T8776	T8773	themeOf	ΔFKH,overexpression
R6744	T8781	T8780	themeOf	Tax,overexpression
R6747	T8783	T8782	themeOf	Foxp3,transfection
R6750	T8787	T8786	themeOf	Foxp3,interact
R6752	T8789	T8788	themeOf	ΔFKH,overexpression
R6759	T8792	T8793	causeOf	Foxp3,down-regulating
R6763	T8794	T8793	themeOf	expression,down-regulating
R6765	T8795	T8794	themeOf	Tax,expression
R6766	T8796	T8797	themeOf	Foxp3,interacts
R6767	T8796	T8798	themeOf	Foxp3,localization
R6768	T8799	T8798	locationOf	nucleus,localization
R6769	T8801	T8803	themeOf	Foxp3,associating
R6770	T8802	T8803	themeOf	Tax,associating
R6773	T8812	T8810	themeOf	Foxp3,overexpression
R6777	T8813	T8811	themeOf	ΔFKH,overexpression
R6779	T8814	T8816	causeOf	Foxp3,interfacing
R6780	T8817	T8816	themeOf	Tax,interfacing
R6785	T8823	T8822	themeOf	Tax,expression
R6788	T8824	T8825	themeOf	Tax,synthesized
R6791	T8824	T8828	themeOf	Tax,produced
R6794	T8825	T8826	themeOf	synthesized,down-regulated
R6797	T8827	T8826	causeOf	Foxp3,down-regulated
R6800	T8829	T8830	causeOf	ΔFKH,affect
R6805	T8831	T8832	themeOf	Tax,expression
R6808	T8832	T8830	themeOf	expression,affect
R6812	T8833	T8834	causeOf	Foxp3,repressing
R6813	T8835	T8834	themeOf	expression,repressing
R6816	T8836	T8835	themeOf	Tax,expression

bionlp-st-ge-2016-reference

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T6705	40-43	Protein	denotes	Tax
T6706	62-67	Protein	denotes	Foxp3
T6707	135-140	Protein	denotes	Foxp3
T6708	206-229	Protein	denotes	tumor necrosis factor-α
T6709	303-308	Protein	denotes	Foxp3
T6710	459-462	Protein	denotes	Tax
T6711	545-548	Protein	denotes	Tax
T6712	690-704	Positive_regulation	denotes	overexpression
T6713	708-713	Protein	denotes	Foxp3
T6714	762-765	Protein	denotes	Tax
T6715	855-860	Protein	denotes	Foxp3
T6716	878-881	Protein	denotes	Tax
T6717	951-964	Positive_regulation	denotes	overexpressed
T6718	951-964	Positive_regulation	denotes	overexpressed
T6719	951-964	Positive_regulation	denotes	overexpressed
T6720	972-975	Protein	denotes	Tax
T6721	989-994	Protein	denotes	Foxp3
T6722	1003-1007	Protein	denotes	ΔFKH
T6723	1115-1118	Protein	denotes	Tax
T6724	1211-1225	Gene_expression	denotes	overexpression
T6725	1211-1225	Gene_expression	denotes	overexpression
T6726	1229-1234	Protein	denotes	Foxp3
T6727	1244-1248	Protein	denotes	ΔFKH
T6728	1261-1264	Protein	denotes	Tax
T6729	1458-1461	Protein	denotes	Tax
T6730	1523-1528	Protein	denotes	Foxp3
T6731	1652-1666	Positive_regulation	denotes	overexpression
T6732	1670-1673	Protein	denotes	Tax
T6733	1693-1705	Gene_expression	denotes	transfection
T6734	1709-1714	Protein	denotes	Foxp3
T6735	1726-1729	Protein	denotes	Tax
T6736	1824-1827	Protein	denotes	Tax
T6737	1905-1913	Binding	denotes	interact
T6738	1919-1924	Protein	denotes	Foxp3
T6739	1940-1954	Positive_regulation	denotes	overexpression
T6740	1958-1962	Protein	denotes	ΔFKH
T6741	2016-2019	Protein	denotes	Tax
T6742	2055-2060	Protein	denotes	Foxp3
T6743	2147-2152	Protein	denotes	Foxp3
T6744	2153-2168	Negative_regulation	denotes	down-regulating
T6745	2173-2183	Gene_expression	denotes	expression
T6746	2203-2206	Protein	denotes	Tax
T6747	2298-2303	Protein	denotes	Foxp3
T6748	2304-2313	Binding	denotes	interacts		true
T6749	2435-2447	Localization	denotes	localization
T6750	2455-2462	Entity	denotes	nucleus
T6751	2499-2502	Protein	denotes	Tax
T6752	3860-3865	Protein	denotes	Foxp3
T6753	3909-3912	Protein	denotes	Tax
T6754	3925-3936	Binding	denotes	associating		true
T6755	4012-4015	Protein	denotes	Tax
T6756	4067-4071	Protein	denotes	Gal4
T6757	4092-4096	Protein	denotes	Gal4
T6758	4107-4118	Protein	denotes	Gal4-BD-Tax
T6759	4224-4228	Protein	denotes	Gal4
T6760	4349-4360	Protein	denotes	Gal4-BD-Tax
T6761	4395-4409	Positive_regulation	denotes	overexpression
T6762	4395-4409	Positive_regulation	denotes	overexpression
T6763	4436-4441	Protein	denotes	Foxp3
T6764	4446-4450	Protein	denotes	ΔFKH
T6765	4468-4473	Protein	denotes	Foxp3
T6766	4491-4494	Protein	denotes	Tax
T6767	4523-4534	Negative_regulation	denotes	interfacing
T6768	4551-4554	Protein	denotes	Tax
T6769	4580-4585	Protein	denotes	Foxp3
T6770	4768-4773	Protein	denotes	Foxp3
T6771	4775-4779	Protein	denotes	ΔFKH
T6772	4914-4917	Protein	denotes	CD4
T6773	5002-5012	Transcription	denotes	expression
T6774	5027-5030	Protein	denotes	Tax
T6775	5130-5133	Protein	denotes	Tax
T6776	5139-5150	Transcription	denotes	synthesized
T6777	5164-5178	Negative_regulation	denotes	down-regulated
T6778	5198-5203	Protein	denotes	Foxp3
T6779	5226-5234	Transcription	denotes	produced
T6780	5274-5278	Protein	denotes	ΔFKH
T6781	5306-5312	Regulation	denotes	affect	true
T6782	5316-5319	Protein	denotes	Tax
T6783	5320-5330	Gene_expression	denotes	expression
T6784	5357-5362	Protein	denotes	Foxp3
T6785	5377-5387	Negative_regulation	denotes	repressing
T6786	5392-5402	Gene_expression	denotes	expression
T6787	5406-5409	Protein	denotes	Tax
R5153	T6732	T6731	themeOf	Tax,overexpression
R5154	T6734	T6733	themeOf	Foxp3,transfection
R5155	T6738	T6737	themeOf	Foxp3,interact
R5156	T6740	T6739	themeOf	ΔFKH,overexpression
R5157	T6743	T6744	causeOf	Foxp3,down-regulating
R5158	T6745	T6744	themeOf	expression,down-regulating
R5159	T6746	T6745	themeOf	Tax,expression
R5160	T6747	T6748	themeOf	Foxp3,interacts
R5161	T6747	T6749	themeOf	Foxp3,localization
R5162	T6750	T6749	locationOf	nucleus,localization
R5163	T6752	T6754	themeOf	Foxp3,associating
R5164	T6753	T6754	themeOf	Tax,associating
R5165	T6763	T6761	themeOf	Foxp3,overexpression
R5166	T6764	T6762	themeOf	ΔFKH,overexpression
R5168	T6768	T6767	themeOf	Tax,interfacing
R5147	T6713	T6712	themeOf	Foxp3,overexpression
R5148	T6720	T6719	themeOf	Tax,overexpressed
R5149	T6721	T6718	themeOf	Foxp3,overexpressed
R5150	T6722	T6717	themeOf	ΔFKH,overexpressed
R5151	T6726	T6725	themeOf	Foxp3,overexpression
R5152	T6727	T6724	themeOf	ΔFKH,overexpression
R5167	T6765	T6767	causeOf	Foxp3,interfacing
R5169	T6774	T6773	themeOf	Tax,expression
R5170	T6775	T6776	themeOf	Tax,synthesized
R5171	T6775	T6779	themeOf	Tax,produced
R5172	T6776	T6777	themeOf	synthesized,down-regulated
R5173	T6778	T6777	causeOf	Foxp3,down-regulated
R5174	T6780	T6781	causeOf	ΔFKH,affect
R5175	T6782	T6783	themeOf	Tax,expression
R5176	T6783	T6781	themeOf	expression,affect
R5177	T6784	T6785	causeOf	Foxp3,repressing
R5178	T6786	T6785	themeOf	expression,repressing
R5179	T6787	T6786	themeOf	Tax,expression

bionlp-st-ge-2016-uniprot

Id	Subject	Object	Predicate	Lexical cue
T8229	40-43	P03409	denotes	Tax
T8230	62-67	Q9BZS1	denotes	Foxp3
T8231	135-140	Q9BZS1	denotes	Foxp3
T8232	206-227	P01375	denotes	tumor necrosis factor
T8233	303-308	Q9BZS1	denotes	Foxp3
T8234	459-462	P03409	denotes	Tax
T8235	505-509	O43889	denotes	CREB
T8236	505-509	Q8TEY5	denotes	CREB
T8237	505-509	P16220	denotes	CREB
T8238	505-509	P15336	denotes	CREB
T8239	505-509	P18848	denotes	CREB
T8240	505-509	Q02930	denotes	CREB
T8241	545-548	P03409	denotes	Tax
T8242	708-713	Q9BZS1	denotes	Foxp3
T8243	762-765	P03409	denotes	Tax
T8244	855-860	Q9BZS1	denotes	Foxp3
T8245	878-881	P03409	denotes	Tax
T8246	972-975	P03409	denotes	Tax
T8247	989-994	Q9BZS1	denotes	Foxp3
T8248	1003-1007	P55316	denotes	ΔFKH
T8249	1115-1118	P03409	denotes	Tax
T8250	1229-1234	Q9BZS1	denotes	Foxp3
T8251	1244-1248	P55316	denotes	ΔFKH
T8252	1261-1264	P03409	denotes	Tax
T8253	1458-1461	P03409	denotes	Tax
T8254	1523-1528	Q9BZS1	denotes	Foxp3
T8255	1670-1673	P03409	denotes	Tax
T8256	1709-1714	Q9BZS1	denotes	Foxp3
T8257	1726-1729	P03409	denotes	Tax
T8258	1824-1827	P03409	denotes	Tax
T8259	1919-1924	Q9BZS1	denotes	Foxp3
T8260	1958-1962	P55316	denotes	ΔFKH
T8261	2016-2019	P03409	denotes	Tax
T8262	2055-2060	Q9BZS1	denotes	Foxp3
T8263	2147-2152	Q9BZS1	denotes	Foxp3
T8264	2203-2206	P03409	denotes	Tax
T8265	2298-2303	Q9BZS1	denotes	Foxp3
T8266	2499-2502	P03409	denotes	Tax
T8267	3860-3865	Q9BZS1	denotes	Foxp3
T8268	3909-3912	P03409	denotes	Tax
T8269	4012-4015	P03409	denotes	Tax
T8270	4067-4071	P04386	denotes	Gal4
T8271	4092-4096	P04386	denotes	Gal4
T8272	4107-4111	P04386	denotes	Gal4
T8273	4115-4118	P03409	denotes	Tax
T8274	4198-4202	P04386	denotes	Gal4
T8275	4224-4228	P04386	denotes	Gal4
T8276	4322-4326	P04386	denotes	Gal4
T8277	4349-4353	P04386	denotes	Gal4
T8278	4357-4360	P03409	denotes	Tax
T8279	4370-4380	Q04864	denotes	relatively
T8280	4436-4441	Q9BZS1	denotes	Foxp3
T8281	4446-4450	P55316	denotes	ΔFKH
T8282	4468-4473	Q9BZS1	denotes	Foxp3
T8283	4491-4494	P03409	denotes	Tax
T8284	4551-4554	P03409	denotes	Tax
T8285	4580-4585	Q9BZS1	denotes	Foxp3
T8286	4768-4773	Q9BZS1	denotes	Foxp3
T8287	4775-4779	P55316	denotes	ΔFKH
T8288	4914-4917	P01730	denotes	CD4
T8289	5027-5030	P03409	denotes	Tax
T8290	5130-5133	P03409	denotes	Tax
T8291	5198-5203	Q9BZS1	denotes	Foxp3
T8292	5274-5278	P55316	denotes	ΔFKH
T8293	5316-5319	P03409	denotes	Tax
T8294	5357-5362	Q9BZS1	denotes	Foxp3
T8295	5406-5409	P03409	denotes	Tax

test2

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T6622	40-43	Protein	denotes	Tax
T6623	48-58	Negative_regulation	denotes	Suppressed
T6624	62-67	Protein	denotes	Foxp3
T6625	135-140	Protein	denotes	Foxp3
T6626	206-229	Protein	denotes	tumor necrosis factor-α
T6627	303-308	Protein	denotes	Foxp3
T6628	459-462	Protein	denotes	Tax
T6629	545-548	Protein	denotes	Tax
T6630	690-704	Positive_regulation	denotes	overexpression
T6631	708-713	Protein	denotes	Foxp3
T6632	762-765	Protein	denotes	Tax
T6633	855-860	Protein	denotes	Foxp3
T6634	878-881	Protein	denotes	Tax		true
T6635	951-964	Gene_expression	denotes	overexpressed
T6636	972-975	Protein	denotes	Tax		true
T6637	989-994	Protein	denotes	Foxp3
T6638	1003-1007	Protein	denotes	ΔFKH
T6639	1115-1118	Protein	denotes	Tax
T6640	1211-1225	Positive_regulation	denotes	overexpression
T6641	1229-1234	Protein	denotes	Foxp3
T6642	1244-1248	Protein	denotes	ΔFKH
T6643	1261-1264	Protein	denotes	Tax
T6644	1458-1461	Protein	denotes	Tax	true
T6645	1523-1528	Protein	denotes	Foxp3
T6646	1652-1666	Positive_regulation	denotes	overexpression
T6647	1670-1673	Protein	denotes	Tax
T6648	1709-1714	Protein	denotes	Foxp3
T6649	1726-1729	Protein	denotes	Tax
T6650	1813-1820	Negative_regulation	denotes	absence
T6651	1824-1827	Protein	denotes	Tax
T6652	1831-1842	Regulation	denotes	independent
T6653	1905-1913	Binding	denotes	interact
T6654	1919-1924	Protein	denotes	Foxp3
T6655	1940-1954	Positive_regulation	denotes	overexpression
T6656	1958-1962	Protein	denotes	ΔFKH
T6657	2016-2019	Protein	denotes	Tax
T6658	2055-2060	Protein	denotes	Foxp3
T6659	2147-2152	Protein	denotes	Foxp3
T6660	2153-2158	Negative_regulation	denotes	down-
T6661	2203-2206	Protein	denotes	Tax
T6662	2298-2303	Protein	denotes	Foxp3
T6663	2304-2313	Binding	denotes	interacts
T6664	2435-2447	Localization	denotes	localization
T6665	2455-2462	Entity	denotes	nucleus
T6666	2499-2502	Protein	denotes	Tax
T6667	3860-3865	Protein	denotes	Foxp3
T6668	3866-3875	Negative_regulation	denotes	inhibited
T6669	3909-3912	Protein	denotes	Tax
T6670	3925-3936	Binding	denotes	associating
T6671	4012-4015	Protein	denotes	Tax
T6672	4067-4071	Protein	denotes	Gal4
T6673	4092-4096	Protein	denotes	Gal4
T6674	4107-4118	Protein	denotes	Gal4-BD-Tax
T6675	4224-4228	Protein	denotes	Gal4
T6676	4262-4275	Transcription	denotes	transcription
T6677	4349-4360	Protein	denotes	Gal4-BD-Tax
T6678	4395-4409	Positive_regulation	denotes	overexpression
T6679	4436-4441	Protein	denotes	Foxp3
T6680	4446-4450	Protein	denotes	ΔFKH
T6681	4468-4473	Protein	denotes	Foxp3
T6682	4483-4490	Negative_regulation	denotes	repress
T6683	4491-4494	Protein	denotes	Tax
T6684	4523-4534	Positive_regulation	denotes	interfacing
T6685	4551-4554	Protein	denotes	Tax
T6686	4580-4585	Protein	denotes	Foxp3
T6687	4768-4773	Protein	denotes	Foxp3
T6688	4775-4779	Protein	denotes	ΔFKH
T6689	4914-4917	Protein	denotes	CD4
T6690	5027-5030	Protein	denotes	Tax
T6691	5130-5133	Protein	denotes	Tax
T6692	5134-5138	Transcription	denotes	mRNA
T6693	5139-5150	Transcription	denotes	synthesized
T6694	5164-5178	Negative_regulation	denotes	down-regulated
T6695	5198-5203	Protein	denotes	Foxp3
T6696	5226-5234	Gene_expression	denotes	produced
T6697	5274-5278	Protein	denotes	ΔFKH
T6698	5306-5312	Regulation	denotes	affect
T6699	5316-5319	Protein	denotes	Tax
T6700	5320-5330	Gene_expression	denotes	expression
T6701	5357-5362	Protein	denotes	Foxp3
T6702	5377-5387	Negative_regulation	denotes	repressing
T6703	5392-5402	Gene_expression	denotes	expression
T6704	5406-5409	Protein	denotes	Tax
R5115	T6631	T6630	themeOf	Foxp3,overexpression
R5116	T6636	T6635	themeOf	Tax,overexpressed
R5117	T6637	T6635	themeOf	Foxp3,overexpressed
R5118	T6638	T6635	themeOf	ΔFKH,overexpressed
R5119	T6641	T6640	themeOf	Foxp3,overexpression
R5120	T6642	T6640	themeOf	ΔFKH,overexpression
R5121	T6647	T6646	themeOf	Tax,overexpression
R5122	T6651	T6650	themeOf	Tax,absence
R5123	T6654	T6653	themeOf	Foxp3,interact
R5124	T6656	T6655	themeOf	ΔFKH,overexpression
R5125	T6662	T6664	themeOf	Foxp3,localization
R5126	T6662	T6663	themeOf	Foxp3,interacts
R5127	T6665	T6663	locationOf	nucleus,interacts
R5128	T6665	T6664	locationOf	nucleus,localization
R5129	T6667	T6670	themeOf	Foxp3,associating
R5130	T6669	T6670	themeOf	Tax,associating
R5131	T6679	T6678	themeOf	Foxp3,overexpression
R5132	T6680	T6678	themeOf	ΔFKH,overexpression
R5133	T6681	T6684	causeOf	Foxp3,interfacing
R5134	T6681	T6682	causeOf	Foxp3,repress
R5135	T6684	T6682	causeOf	interfacing,repress
R5136	T6685	T6684	themeOf	Tax,interfacing
R5137	T6691	T6693	themeOf	Tax,synthesized
R5138	T6693	T6694	themeOf	synthesized,down-regulated
R5139	T6695	T6696	themeOf	Foxp3,produced
R5140	T6695	T6694	causeOf	Foxp3,down-regulated
R5141	T6696	T6694	causeOf	produced,down-regulated
R5142	T6697	T6698	causeOf	ΔFKH,affect
R5143	T6699	T6700	themeOf	Tax,expression
R5144	T6700	T6698	themeOf	expression,affect
R5145	T6703	T6702	themeOf	expression,repressing
R5146	T6704	T6703	themeOf	Tax,expression

PMC:1447668 / 17683-23570 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:1447668 / 17683-23570 JSON TXT