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PMC:1447668 / 14569-17684 JSONTXT

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bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T6499 0-5 Protein denotes Foxp3
T6500 78-83 Protein denotes NF-κB
T6501 64-74 Positive_regulation denotes Activation
T6502 87-92 Protein denotes Foxp3
T6503 121-126 Protein denotes NF-κB
T6504 180-185 Protein denotes Foxp3
T6505 299-304 Protein denotes NF-κB
T6506 186-200 Positive_regulation denotes overexpression
T6507 382-391 Protein denotes HIV-1 LTR
T6508 430-435 Protein denotes NF-κB
T6509 364-374 Positive_regulation denotes activation
T6510 545-550 Protein denotes NF-κB
T6511 633-637 Protein denotes CD4+
T6512 682-687 Protein denotes Foxp3
T6513 697-701 Protein denotes ΔFKH
T6514 706-714 Protein denotes HEK 293T
T6515 851-856 Protein denotes NF-κB
T6516 652-666 Positive_regulation denotes Overexpression
T6517 652-666 Positive_regulation denotes Overexpression
T6518 950-955 Protein denotes Foxp3
T6519 960-964 Protein denotes ΔFKH
T6520 1016-1021 Protein denotes Foxp3
T6521 1090-1095 Protein denotes NF-κB
T6522 1156-1165 Protein denotes HIV-1 LTR
T6523 1072-1084 Binding denotes interactions
T6524 1096-1101 Binding denotes bound
T6525 1485-1490 Protein denotes Foxp3
T6526 1571-1576 Protein denotes Foxp3
T6527 1491-1505 Positive_regulation denotes overexpression
T6528 1739-1744 Protein denotes Foxp3
T6529 1764-1773 Protein denotes HIV-1 LTR
T6530 1829-1834 Protein denotes NF-κB
T6531 1745-1760 Negative_regulation denotes down-regulation
T6532 1774-1784 Positive_regulation denotes activation
T6533 1745-1760 Negative_regulation denotes down-regulation
T6534 1887-1901 Protein denotes HIV-1 Δ-κB LTR
T6535 1905-1910 Protein denotes Foxp3
T6536 1925-1930 Protein denotes NF-AT
T6537 1969-1980 Protein denotes NF-κB sites
T6538 1869-1879 Negative_regulation denotes inhibition
R5069 T6500 T6501 themeOf NF-κB,Activation
R5070 T6504 T6506 themeOf Foxp3,overexpression
R5071 T6507 T6509 themeOf HIV-1 LTR,activation
R5072 T6512 T6516 themeOf Foxp3,Overexpression
R5073 T6513 T6517 themeOf ΔFKH,Overexpression
R5074 T6521 T6523 themeOf NF-κB,interactions
R5075 T6521 T6524 themeOf NF-κB,bound
R5076 T6525 T6527 themeOf Foxp3,overexpression
R5077 T6528 T6531 themeOf Foxp3,down-regulation
R5078 T6529 T6532 themeOf HIV-1 LTR,activation
R5079 T6532 T6533 themeOf activation,down-regulation
R5080 T6534 T6538 themeOf HIV-1 Δ-κB LTR,inhibition
R5081 T6535 T6538 causeOf Foxp3,inhibition

sentences

Id Subject Object Predicate Lexical cue
T5628 0-83 Sentence denotes Foxp3 Suppresses HIV-1 Gene Expression in Part through Blocking Activation of NF-κB
T5629 84-305 Sentence denotes If Foxp3 functions as a repressor of NF-κB-dependent gene expression, then we hypothesized that Foxp3 overexpression could selectively down-regulate transcription from promoters previously shown to be responsive to NF-κB.
T5630 306-544 Sentence denotes To address this question, we examined the transcriptional activation of the HIV-1 LTR, which contains two tandem cis-acting NF-κB binding sites located between positions −102 and −81 with respect to the transcription initiation site [21].
T5631 545-651 Sentence denotes NF-κB plays a crucial role in regulating gene expression directed from the HIV-1 LTR in CD4+ T cells [21].
T5632 652-885 Sentence denotes Overexpression of full-length Foxp3, but not ΔFKH, in HEK 293T cells was able to inhibit basal activation of the HIV-1 LTR (Figure 3A), similar to what was previously demonstrated with the synthetic NF-κB reporter vector (Figure 2B).
T5633 886-995 Sentence denotes Furthermore, HIV-1 LTR activation was suppressed by full-length Foxp3 and ΔFKH in Jurkat T cells (Figure 3B).
T5634 996-1274 Sentence denotes To demonstrate that Foxp3-mediated HIV-1 LTR repression was associated with interactions with NF-κB bound to the HIV-1 LTR, we compared basal activation of the HIV-1 LTR or an identical HIV-1 LTR lacking the NF-κB sites located between −102 and −81 (HIV-1 Δ-κB LTR) (Figure 3C).
T5635 1275-1442 Sentence denotes This mutant HIV-1 LTR construct exhibited reduced levels of transcription compared to the parental HIV-1 LTR in purified healthy donor CD4+ T cells (unpublished data).
T5636 1443-1711 Sentence denotes However, directly comparing the effect of Foxp3 overexpression on the activation of these two viral promoters demonstrated that Foxp3 was more capable of suppressing transcriptional activation of the HIV-1 LTR (Figure 3D) compared to the mutated HIV-1 LTR (Figure 3E).
T5637 1712-1849 Sentence denotes These results suggest that Foxp3 down-regulation of HIV-1 LTR activation was mediated at least in part by cis-acting NF-κB binding sites.
T5638 1850-2010 Sentence denotes Residual levels of inhibition of the HIV-1 Δ-κB LTR by Foxp3 may be due to NF-AT binding sites located upstream of the NF-κB sites within the HIV-1 LTR [22,23].
T79 0-83 Sentence denotes Foxp3 Suppresses HIV-1 Gene Expression in Part through Blocking Activation of NF-κB
T80 84-305 Sentence denotes If Foxp3 functions as a repressor of NF-κB-dependent gene expression, then we hypothesized that Foxp3 overexpression could selectively down-regulate transcription from promoters previously shown to be responsive to NF-κB.
T81 306-544 Sentence denotes To address this question, we examined the transcriptional activation of the HIV-1 LTR, which contains two tandem cis-acting NF-κB binding sites located between positions −102 and −81 with respect to the transcription initiation site [21].
T82 545-651 Sentence denotes NF-κB plays a crucial role in regulating gene expression directed from the HIV-1 LTR in CD4+ T cells [21].
T83 652-885 Sentence denotes Overexpression of full-length Foxp3, but not ΔFKH, in HEK 293T cells was able to inhibit basal activation of the HIV-1 LTR (Figure 3A), similar to what was previously demonstrated with the synthetic NF-κB reporter vector (Figure 2B).
T84 886-995 Sentence denotes Furthermore, HIV-1 LTR activation was suppressed by full-length Foxp3 and ΔFKH in Jurkat T cells (Figure 3B).
T85 996-1274 Sentence denotes To demonstrate that Foxp3-mediated HIV-1 LTR repression was associated with interactions with NF-κB bound to the HIV-1 LTR, we compared basal activation of the HIV-1 LTR or an identical HIV-1 LTR lacking the NF-κB sites located between −102 and −81 (HIV-1 Δ-κB LTR) (Figure 3C).
T86 1275-1442 Sentence denotes This mutant HIV-1 LTR construct exhibited reduced levels of transcription compared to the parental HIV-1 LTR in purified healthy donor CD4+ T cells (unpublished data).
T87 1443-1711 Sentence denotes However, directly comparing the effect of Foxp3 overexpression on the activation of these two viral promoters demonstrated that Foxp3 was more capable of suppressing transcriptional activation of the HIV-1 LTR (Figure 3D) compared to the mutated HIV-1 LTR (Figure 3E).
T88 1712-1849 Sentence denotes These results suggest that Foxp3 down-regulation of HIV-1 LTR activation was mediated at least in part by cis-acting NF-κB binding sites.
T89 1850-2010 Sentence denotes Residual levels of inhibition of the HIV-1 Δ-κB LTR by Foxp3 may be due to NF-AT binding sites located upstream of the NF-κB sites within the HIV-1 LTR [22,23].
T90 2011-2069 Sentence denotes Figure 3 Foxp3 Inhibits Basal Activation of the HIV-1 LTR
T91 2070-2453 Sentence denotes (A and B) HEK 293T cells (5 × 105) (A) were seeded into six-well plates 1 d prior to transfection or Jurkat T cells (1 × 106) (B) were seeded into six-well plates on the day of transfection with an HIV-1 LTR luciferase reporter vector (200 ng) in the presence or absence of a Foxp3, ΔFKH, or control expression vector (1,000 ng) and internal reference plasmid (pGL4-TKhRluc2; 50 ng).
T92 2454-2537 Sentence denotes Cells were harvested at 24 h posttransfection and analyzed for luciferase activity.
T93 2538-2650 Sentence denotes (C) Schematic representation of HIV-1 LTR luciferase reporter constructs pHIV-1 LTR-luc and pHIV-1 Δ-κB LTR-luc.
T94 2651-2928 Sentence denotes (D and E) CD4+ T cells (2 × 106) from two healthy donors were nucleofected with either parental HIV-1 LTR (D) or HIV-1 LTR lacking NF-κB binding sites (at −102 to −81) (E) (1,000 ng), Foxp3 or control expression vectors (2,000 ng), and an internal reference plasmid (1,000 ng).
T95 2929-3009 Sentence denotes Cells were harvested 24 h posttransfection and analyzed for luciferase activity.
T96 3010-3112 Sentence denotes Relative luciferase activity shown in A, B, D, and E was normalized to the internal reference control.

2_test

Id Subject Object Predicate Lexical cue
16652169-10692237-98518410 2003-2005 10692237 denotes 22
16652169-1909027-98518411 2006-2008 1909027 denotes 23

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T6003 0-5 CD denotes Foxp3
T6004 6-16 VB denotes Suppresses
T6005 17-22 NN denotes HIV-1
T6006 23-27 NN denotes Gene
T6007 28-38 NN denotes Expression
T6008 39-41 IN denotes in
T6009 42-46 NNP denotes Part
T6010 47-54 IN denotes through
T6011 55-63 VB denotes Blocking
T6012 64-74 NN denotes Activation
T6013 75-77 IN denotes of
T6014 78-83 NN denotes NF-κB
T6015 84-86 IN denotes If
T6016 87-92 NN denotes Foxp3
T6017 93-102 VB denotes functions
T6018 103-105 IN denotes as
T6019 106-107 DT denotes a
T6020 108-117 NN denotes repressor
T6021 118-120 IN denotes of
T6022 121-136 JJ denotes NF-κB-dependent
T6023 137-141 NN denotes gene
T6024 142-152 NN denotes expression
T6025 152-153 -COMMA- denotes ,
T6026 154-158 RB denotes then
T6027 159-161 PRP denotes we
T6028 162-174 VB denotes hypothesized
T6029 175-179 IN denotes that
T6030 180-185 NN denotes Foxp3
T6031 186-200 NN denotes overexpression
T6032 201-206 MD denotes could
T6033 207-218 RB denotes selectively
T6034 219-232 VB denotes down-regulate
T6035 233-246 NN denotes transcription
T6036 247-251 IN denotes from
T6037 252-261 NN denotes promoters
T6038 262-272 RB denotes previously
T6039 273-278 VB denotes shown
T6040 279-281 TO denotes to
T6041 282-284 VB denotes be
T6042 285-295 JJ denotes responsive
T6043 296-298 TO denotes to
T6044 299-304 NN denotes NF-κB
T6045 306-308 TO denotes To
T6046 309-316 VB denotes address
T6047 317-321 DT denotes this
T6048 322-330 NN denotes question
T6049 330-331 -COMMA- denotes ,
T6050 332-334 PRP denotes we
T6051 335-343 VB denotes examined
T6052 344-347 DT denotes the
T6053 348-363 JJ denotes transcriptional
T6054 364-374 NN denotes activation
T6055 375-377 IN denotes of
T6056 378-381 DT denotes the
T6057 382-387 NN denotes HIV-1
T6058 388-391 NN denotes LTR
T6059 391-392 -COMMA- denotes ,
T6060 393-398 WDT denotes which
T6061 399-407 VB denotes contains
T6062 408-411 CD denotes two
T6063 412-418 JJ denotes tandem
T6064 419-429 JJ denotes cis-acting
T6065 430-435 NN denotes NF-κB
T6066 436-443 NN denotes binding
T6067 444-449 NN denotes sites
T6068 450-457 JJ denotes located
T6069 458-465 IN denotes between
T6070 466-475 NN denotes positions
T6071 476-480 CD denotes −102
T6072 481-484 CC denotes and
T6073 485-488 CD denotes −81
T6074 489-493 IN denotes with
T6075 494-501 NN denotes respect
T6076 502-504 TO denotes to
T6077 505-508 DT denotes the
T6078 509-522 NN denotes transcription
T6079 523-533 NN denotes initiation
T6080 534-538 NN denotes site
T6081 539-540 -LRB- denotes [
T6082 540-542 CD denotes 21
T6083 542-543 -RRB- denotes ]
T6084 545-550 NN denotes NF-κB
T6085 551-556 VB denotes plays
T6086 557-558 DT denotes a
T6087 559-566 JJ denotes crucial
T6088 567-571 NN denotes role
T6089 572-574 IN denotes in
T6090 575-585 VB denotes regulating
T6091 586-590 NN denotes gene
T6092 591-601 NN denotes expression
T6093 602-610 VB denotes directed
T6094 611-615 IN denotes from
T6095 616-619 DT denotes the
T6096 620-625 NN denotes HIV-1
T6097 626-629 NN denotes LTR
T6098 630-632 IN denotes in
T6099 633-637 JJ denotes CD4+
T6100 638-639 NN denotes T
T6101 640-645 NN denotes cells
T6102 646-647 -LRB- denotes [
T6103 647-649 CD denotes 21
T6104 649-650 -RRB- denotes ]
T6105 652-666 NN denotes Overexpression
T6106 667-669 IN denotes of
T6107 670-681 JJ denotes full-length
T6108 682-687 NN denotes Foxp3
T6109 687-688 -COMMA- denotes ,
T6110 689-692 CC denotes but
T6111 693-696 RB denotes not
T6112 697-701 NN denotes ΔFKH
T6113 701-702 -COMMA- denotes ,
T6114 703-705 IN denotes in
T6115 706-709 NN denotes HEK
T6116 710-714 NN denotes 293T
T6117 715-720 NN denotes cells
T6118 721-724 VB denotes was
T6119 725-729 JJ denotes able
T6120 730-732 TO denotes to
T6121 733-740 VB denotes inhibit
T6122 741-746 JJ denotes basal
T6123 747-757 NN denotes activation
T6124 758-760 IN denotes of
T6125 761-764 DT denotes the
T6126 765-770 NN denotes HIV-1
T6127 771-774 NN denotes LTR
T6128 775-776 -LRB- denotes (
T6129 776-782 NN denotes Figure
T6130 783-785 NN denotes 3A
T6131 785-786 -RRB- denotes )
T6132 786-787 -COMMA- denotes ,
T6133 788-795 JJ denotes similar
T6134 796-798 TO denotes to
T6135 799-803 WP denotes what
T6136 804-807 VB denotes was
T6137 808-818 RB denotes previously
T6138 819-831 VB denotes demonstrated
T6139 832-836 IN denotes with
T6140 837-840 DT denotes the
T6141 841-850 JJ denotes synthetic
T6142 851-856 NN denotes NF-κB
T6143 857-865 NN denotes reporter
T6144 866-872 NN denotes vector
T6145 873-874 -LRB- denotes (
T6146 874-880 NN denotes Figure
T6147 881-883 NN denotes 2B
T6148 883-884 -RRB- denotes )
T6149 886-897 RB denotes Furthermore
T6150 897-898 -COMMA- denotes ,
T6151 899-904 NN denotes HIV-1
T6152 905-908 NN denotes LTR
T6153 909-919 NN denotes activation
T6154 920-923 VB denotes was
T6155 924-934 VB denotes suppressed
T6156 935-937 IN denotes by
T6157 938-949 JJ denotes full-length
T6158 950-955 NN denotes Foxp3
T6159 956-959 CC denotes and
T6160 960-964 NN denotes ΔFKH
T6161 965-967 IN denotes in
T6162 968-974 NN denotes Jurkat
T6163 975-976 NN denotes T
T6164 977-982 NN denotes cells
T6165 983-984 -LRB- denotes (
T6166 984-990 NN denotes Figure
T6167 991-993 NN denotes 3B
T6168 993-994 -RRB- denotes )
T6169 996-998 TO denotes To
T6170 999-1010 VB denotes demonstrate
T6171 1011-1015 IN denotes that
T6172 1016-1030 JJ denotes Foxp3-mediated
T6173 1031-1036 NN denotes HIV-1
T6174 1037-1040 NN denotes LTR
T6175 1041-1051 NN denotes repression
T6176 1052-1055 VB denotes was
T6177 1056-1066 VB denotes associated
T6178 1067-1071 IN denotes with
T6179 1072-1084 NN denotes interactions
T6180 1085-1089 IN denotes with
T6181 1090-1095 NN denotes NF-κB
T6182 1096-1101 VB denotes bound
T6183 1102-1104 TO denotes to
T6184 1105-1108 DT denotes the
T6185 1109-1114 NN denotes HIV-1
T6186 1115-1118 NN denotes LTR
T6187 1118-1119 -COMMA- denotes ,
T6188 1120-1122 PRP denotes we
T6189 1123-1131 VB denotes compared
T6190 1132-1137 JJ denotes basal
T6191 1138-1148 NN denotes activation
T6192 1149-1151 IN denotes of
T6193 1152-1155 DT denotes the
T6194 1156-1161 NN denotes HIV-1
T6195 1162-1165 NN denotes LTR
T6196 1166-1168 CC denotes or
T6197 1169-1171 DT denotes an
T6198 1172-1181 JJ denotes identical
T6199 1182-1187 NN denotes HIV-1
T6200 1188-1191 NN denotes LTR
T6201 1192-1199 VB denotes lacking
T6202 1200-1203 DT denotes the
T6203 1204-1209 NN denotes NF-κB
T6204 1210-1215 NN denotes sites
T6205 1216-1223 JJ denotes located
T6206 1224-1231 IN denotes between
T6207 1232-1236 CD denotes −102
T6208 1237-1240 CC denotes and
T6209 1241-1244 CD denotes −81
T6210 1245-1246 -LRB- denotes (
T6211 1246-1251 NN denotes HIV-1
T6212 1252-1256 NN denotes Δ-κB
T6213 1257-1260 NN denotes LTR
T6214 1260-1261 -RRB- denotes )
T6215 1262-1263 -LRB- denotes (
T6216 1263-1269 NN denotes Figure
T6217 1270-1272 NN denotes 3C
T6218 1272-1273 -RRB- denotes )
T6219 1275-1279 DT denotes This
T6220 1280-1286 JJ denotes mutant
T6221 1287-1292 NN denotes HIV-1
T6222 1293-1296 NN denotes LTR
T6223 1297-1306 NN denotes construct
T6224 1307-1316 VB denotes exhibited
T6225 1317-1324 VB denotes reduced
T6226 1325-1331 NN denotes levels
T6227 1332-1334 IN denotes of
T6228 1335-1348 NN denotes transcription
T6229 1349-1357 VB denotes compared
T6230 1358-1360 TO denotes to
T6231 1361-1364 DT denotes the
T6232 1365-1373 JJ denotes parental
T6233 1374-1379 NN denotes HIV-1
T6234 1380-1383 NN denotes LTR
T6235 1384-1386 IN denotes in
T6236 1387-1395 VB denotes purified
T6237 1396-1403 JJ denotes healthy
T6238 1404-1409 NN denotes donor
T6239 1410-1414 JJ denotes CD4+
T6240 1415-1416 NN denotes T
T6241 1417-1422 NN denotes cells
T6242 1423-1424 -LRB- denotes (
T6243 1424-1435 JJ denotes unpublished
T6244 1436-1440 NN denotes data
T6245 1440-1441 -RRB- denotes )
T6246 1443-1450 RB denotes However
T6247 1450-1451 -COMMA- denotes ,
T6248 1452-1460 RB denotes directly
T6249 1461-1470 VB denotes comparing
T6250 1471-1474 DT denotes the
T6251 1475-1481 NN denotes effect
T6252 1482-1484 IN denotes of
T6253 1485-1490 NN denotes Foxp3
T6254 1491-1505 NN denotes overexpression
T6255 1506-1508 IN denotes on
T6256 1509-1512 DT denotes the
T6257 1513-1523 NN denotes activation
T6258 1524-1526 IN denotes of
T6259 1527-1532 DT denotes these
T6260 1533-1536 CD denotes two
T6261 1537-1542 JJ denotes viral
T6262 1543-1552 NN denotes promoters
T6263 1553-1565 VB denotes demonstrated
T6264 1566-1570 IN denotes that
T6265 1571-1576 NN denotes Foxp3
T6266 1577-1580 VB denotes was
T6267 1581-1585 RB denotes more
T6268 1586-1593 JJ denotes capable
T6269 1594-1596 IN denotes of
T6270 1597-1608 VB denotes suppressing
T6271 1609-1624 JJ denotes transcriptional
T6272 1625-1635 NN denotes activation
T6273 1636-1638 IN denotes of
T6274 1639-1642 DT denotes the
T6275 1643-1648 NN denotes HIV-1
T6276 1649-1652 NN denotes LTR
T6277 1653-1654 -LRB- denotes (
T6278 1654-1660 NN denotes Figure
T6279 1661-1663 NN denotes 3D
T6280 1663-1664 -RRB- denotes )
T6281 1665-1673 VB denotes compared
T6282 1674-1676 TO denotes to
T6283 1677-1680 DT denotes the
T6284 1681-1688 VB denotes mutated
T6285 1689-1694 NN denotes HIV-1
T6286 1695-1698 NN denotes LTR
T6287 1699-1700 -LRB- denotes (
T6288 1700-1706 NN denotes Figure
T6289 1707-1709 NN denotes 3E
T6290 1709-1710 -RRB- denotes )
T6291 1712-1717 DT denotes These
T6292 1718-1725 NN denotes results
T6293 1726-1733 VB denotes suggest
T6294 1734-1738 IN denotes that
T6295 1739-1744 NN denotes Foxp3
T6296 1745-1760 NN denotes down-regulation
T6297 1761-1763 IN denotes of
T6298 1764-1769 NN denotes HIV-1
T6299 1770-1773 NN denotes LTR
T6300 1774-1784 NN denotes activation
T6301 1785-1788 VB denotes was
T6302 1789-1797 VB denotes mediated
T6303 1798-1800 IN denotes at
T6304 1801-1806 JJ denotes least
T6305 1807-1809 IN denotes in
T6306 1810-1814 NN denotes part
T6307 1815-1817 IN denotes by
T6308 1818-1828 JJ denotes cis-acting
T6309 1829-1834 NN denotes NF-κB
T6310 1835-1842 NN denotes binding
T6311 1843-1848 NN denotes sites
T6312 1850-1858 JJ denotes Residual
T6313 1859-1865 NN denotes levels
T6314 1866-1868 IN denotes of
T6315 1869-1879 NN denotes inhibition
T6316 1880-1882 IN denotes of
T6317 1883-1886 DT denotes the
T6318 1887-1892 NN denotes HIV-1
T6319 1893-1897 NN denotes Δ-κB
T6320 1898-1901 NN denotes LTR
T6321 1902-1904 IN denotes by
T6322 1905-1910 NN denotes Foxp3
T6323 1911-1914 MD denotes may
T6324 1915-1917 VB denotes be
T6325 1918-1921 JJ denotes due
T6326 1922-1924 TO denotes to
T6327 1925-1930 NN denotes NF-AT
T6328 1931-1938 NN denotes binding
T6329 1939-1944 NN denotes sites
T6330 1945-1952 JJ denotes located
T6331 1953-1961 RB denotes upstream
T6332 1962-1964 IN denotes of
T6333 1965-1968 DT denotes the
T6334 1969-1974 NN denotes NF-κB
T6335 1975-1980 NN denotes sites
T6336 1981-1987 IN denotes within
T6337 1988-1991 DT denotes the
T6338 1992-1997 NN denotes HIV-1
T6339 1998-2001 NN denotes LTR
T6340 2002-2003 -LRB- denotes [
T6341 2003-2008 CD denotes 22,23
T6342 2008-2009 -RRB- denotes ]
R4690 T6003 T6004 arg1Of Foxp3,Suppresses
R4691 T6004 T6008 arg1Of Suppresses,in
R4692 T6004 T6010 arg1Of Suppresses,through
R4693 T6007 T6004 arg2Of Expression,Suppresses
R4694 T6007 T6005 arg1Of Expression,HIV-1
R4695 T6007 T6006 arg1Of Expression,Gene
R4696 T6009 T6008 arg2Of Part,in
R4697 T6011 T6010 arg2Of Blocking,through
R4698 T6012 T6011 arg2Of Activation,Blocking
R4699 T6012 T6013 arg1Of Activation,of
R4700 T6014 T6013 arg2Of NF-κB,of
R4701 T6016 T6017 arg1Of Foxp3,functions
R4702 T6017 T6015 arg2Of functions,If
R4703 T6017 T6018 arg1Of functions,as
R4704 T6020 T6018 arg2Of repressor,as
R4705 T6020 T6019 arg1Of repressor,a
R4706 T6020 T6021 arg1Of repressor,of
R4707 T6024 T6021 arg2Of expression,of
R4708 T6024 T6022 arg1Of expression,NF-κB-dependent
R4709 T6024 T6023 arg1Of expression,gene
R4710 T6027 T6028 arg1Of we,hypothesized
R4711 T6028 T6015 arg1Of hypothesized,If
R4712 T6028 T6025 arg1Of hypothesized,","
R4713 T6028 T6026 arg1Of hypothesized,then
R4714 T6031 T6030 arg1Of overexpression,Foxp3
R4715 T6031 T6032 arg1Of overexpression,could
R4716 T6031 T6034 arg1Of overexpression,down-regulate
R4717 T6034 T6028 arg2Of down-regulate,hypothesized
R4718 T6034 T6029 arg1Of down-regulate,that
R4719 T6034 T6032 arg2Of down-regulate,could
R4720 T6034 T6033 arg1Of down-regulate,selectively
R4721 T6035 T6034 arg2Of transcription,down-regulate
R4722 T6035 T6036 arg1Of transcription,from
R4723 T6037 T6036 arg2Of promoters,from
R4724 T6037 T6039 arg2Of promoters,shown
R4725 T6037 T6041 arg1Of promoters,be
R4726 T6037 T6042 arg1Of promoters,responsive
R4727 T6039 T6038 arg1Of shown,previously
R4728 T6041 T6039 arg3Of be,shown
R4729 T6041 T6040 arg1Of be,to
R4730 T6042 T6041 arg2Of responsive,be
R4731 T6042 T6043 arg1Of responsive,to
R4732 T6044 T6043 arg2Of NF-κB,to
R4733 T6046 T6045 arg1Of address,To
R4734 T6048 T6046 arg2Of question,address
R4735 T6048 T6047 arg1Of question,this
R4736 T6050 T6046 arg1Of we,address
R4737 T6050 T6051 arg1Of we,examined
R4738 T6051 T6045 modOf examined,To
R4739 T6051 T6049 arg1Of examined,","
R4740 T6054 T6051 arg2Of activation,examined
R4741 T6054 T6052 arg1Of activation,the
R4742 T6054 T6053 arg1Of activation,transcriptional
R4743 T6054 T6055 arg1Of activation,of
R4744 T6054 T6059 arg1Of activation,","
R4745 T6054 T6060 arg1Of activation,which
R4746 T6054 T6061 arg1Of activation,contains
R4747 T6058 T6055 arg2Of LTR,of
R4748 T6058 T6056 arg1Of LTR,the
R4749 T6058 T6057 arg1Of LTR,HIV-1
R4750 T6061 T6074 arg1Of contains,with
R4751 T6061 T6081 arg1Of contains,[
R4752 T6067 T6061 arg2Of sites,contains
R4753 T6067 T6062 arg1Of sites,two
R4754 T6067 T6063 arg1Of sites,tandem
R4755 T6067 T6064 arg1Of sites,cis-acting
R4756 T6067 T6065 arg1Of sites,NF-κB
R4757 T6067 T6066 arg1Of sites,binding
R4758 T6067 T6068 arg1Of sites,located
R4759 T6068 T6069 arg1Of located,between
R4760 T6071 T6072 arg1Of −102,and
R4761 T6072 T6069 arg2Of and,between
R4762 T6072 T6070 arg1Of and,positions
R4763 T6073 T6072 arg2Of −81,and
R4764 T6074 T6076 arg1Of with,to
R4765 T6075 T6074 arg2Of respect,with
R4766 T6080 T6074 arg3Of site,with
R4767 T6080 T6077 arg1Of site,the
R4768 T6080 T6078 arg1Of site,transcription
R4769 T6080 T6079 arg1Of site,initiation
R4770 T6082 T6081 arg2Of 21,[
R4771 T6083 T6081 arg3Of ],[
R4772 T6084 T6085 arg1Of NF-κB,plays
R4773 T6085 T6089 arg1Of plays,in
R4774 T6088 T6085 arg2Of role,plays
R4775 T6088 T6086 arg1Of role,a
R4776 T6088 T6087 arg1Of role,crucial
R4777 T6090 T6089 arg2Of regulating,in
R4778 T6092 T6090 arg2Of expression,regulating
R4779 T6092 T6091 arg1Of expression,gene
R4780 T6092 T6093 arg2Of expression,directed
R4781 T6093 T6094 arg1Of directed,from
R4782 T6093 T6098 arg1Of directed,in
R4783 T6093 T6102 arg1Of directed,[
R4784 T6097 T6094 arg2Of LTR,from
R4785 T6097 T6095 arg1Of LTR,the
R4786 T6097 T6096 arg1Of LTR,HIV-1
R4787 T6101 T6098 arg2Of cells,in
R4788 T6101 T6099 arg1Of cells,CD4+
R4789 T6101 T6100 arg1Of cells,T
R4790 T6103 T6102 arg2Of 21,[
R4791 T6104 T6102 arg3Of ],[
R4792 T6105 T6106 arg1Of Overexpression,of
R4793 T6105 T6113 arg1Of Overexpression,","
R4794 T6105 T6114 arg1Of Overexpression,in
R4795 T6105 T6118 arg1Of Overexpression,was
R4796 T6105 T6119 arg1Of Overexpression,able
R4797 T6105 T6121 arg1Of Overexpression,inhibit
R4798 T6108 T6107 arg1Of Foxp3,full-length
R4799 T6108 T6110 arg1Of Foxp3,but
R4800 T6110 T6106 arg2Of but,of
R4801 T6110 T6109 arg1Of but,","
R4802 T6110 T6111 arg1Of but,not
R4803 T6112 T6110 arg2Of ΔFKH,but
R4804 T6117 T6114 arg2Of cells,in
R4805 T6117 T6115 arg1Of cells,HEK
R4806 T6117 T6116 arg1Of cells,293T
R4807 T6119 T6118 arg2Of able,was
R4808 T6121 T6119 arg2Of inhibit,able
R4809 T6121 T6120 arg1Of inhibit,to
R4810 T6123 T6121 arg2Of activation,inhibit
R4811 T6123 T6122 arg1Of activation,basal
R4812 T6123 T6124 arg1Of activation,of
R4813 T6127 T6124 arg2Of LTR,of
R4814 T6127 T6125 arg1Of LTR,the
R4815 T6127 T6126 arg1Of LTR,HIV-1
R4816 T6127 T6128 arg1Of LTR,(
R4817 T6127 T6132 arg1Of LTR,","
R4818 T6127 T6133 arg1Of LTR,similar
R4819 T6130 T6128 arg2Of 3A,(
R4820 T6130 T6129 arg1Of 3A,Figure
R4821 T6131 T6128 arg3Of ),(
R4822 T6133 T6134 arg1Of similar,to
R4823 T6135 T6134 arg2Of what,to
R4824 T6135 T6136 arg1Of what,was
R4825 T6135 T6138 arg2Of what,demonstrated
R4826 T6138 T6136 arg2Of demonstrated,was
R4827 T6138 T6137 arg1Of demonstrated,previously
R4828 T6138 T6139 arg1Of demonstrated,with
R4829 T6144 T6139 arg2Of vector,with
R4830 T6144 T6140 arg1Of vector,the
R4831 T6144 T6141 arg1Of vector,synthetic
R4832 T6144 T6142 arg1Of vector,NF-κB
R4833 T6144 T6143 arg1Of vector,reporter
R4834 T6144 T6145 arg1Of vector,(
R4835 T6147 T6145 arg2Of 2B,(
R4836 T6147 T6146 arg1Of 2B,Figure
R4837 T6148 T6145 arg3Of ),(
R4838 T6153 T6151 arg1Of activation,HIV-1
R4839 T6153 T6152 arg1Of activation,LTR
R4840 T6153 T6154 arg1Of activation,was
R4841 T6153 T6155 arg2Of activation,suppressed
R4842 T6155 T6149 arg1Of suppressed,Furthermore
R4843 T6155 T6150 arg1Of suppressed,","
R4844 T6155 T6154 arg2Of suppressed,was
R4845 T6158 T6159 arg1Of Foxp3,and
R4846 T6159 T6155 arg1Of and,suppressed
R4847 T6159 T6156 arg2Of and,by
R4848 T6159 T6157 arg1Of and,full-length
R4849 T6159 T6161 arg1Of and,in
R4850 T6160 T6159 arg2Of ΔFKH,and
R4851 T6164 T6161 arg2Of cells,in
R4852 T6164 T6162 arg1Of cells,Jurkat
R4853 T6164 T6163 arg1Of cells,T
R4854 T6164 T6165 arg1Of cells,(
R4855 T6167 T6165 arg2Of 3B,(
R4856 T6167 T6166 arg1Of 3B,Figure
R4857 T6168 T6165 arg3Of ),(
R4858 T6170 T6169 arg1Of demonstrate,To
R4859 T6175 T6172 arg1Of repression,Foxp3-mediated
R4860 T6175 T6173 arg1Of repression,HIV-1
R4861 T6175 T6174 arg1Of repression,LTR
R4862 T6175 T6176 arg1Of repression,was
R4863 T6175 T6177 arg2Of repression,associated
R4864 T6177 T6170 arg2Of associated,demonstrate
R4865 T6177 T6171 arg1Of associated,that
R4866 T6177 T6176 arg2Of associated,was
R4867 T6177 T6178 arg1Of associated,with
R4868 T6177 T6183 arg1Of associated,to
R4869 T6179 T6178 arg2Of interactions,with
R4870 T6179 T6180 arg1Of interactions,with
R4871 T6179 T6182 arg2Of interactions,bound
R4872 T6181 T6180 arg2Of NF-κB,with
R4873 T6186 T6183 arg2Of LTR,to
R4874 T6186 T6184 arg1Of LTR,the
R4875 T6186 T6185 arg1Of LTR,HIV-1
R4876 T6188 T6170 arg1Of we,demonstrate
R4877 T6188 T6189 arg1Of we,compared
R4878 T6189 T6169 modOf compared,To
R4879 T6189 T6187 arg1Of compared,","
R4880 T6191 T6190 arg1Of activation,basal
R4881 T6191 T6192 arg1Of activation,of
R4882 T6191 T6196 arg1Of activation,or
R4883 T6195 T6192 arg2Of LTR,of
R4884 T6195 T6193 arg1Of LTR,the
R4885 T6195 T6194 arg1Of LTR,HIV-1
R4886 T6196 T6189 arg2Of or,compared
R4887 T6200 T6196 arg2Of LTR,or
R4888 T6200 T6197 arg1Of LTR,an
R4889 T6200 T6198 arg1Of LTR,identical
R4890 T6200 T6199 arg1Of LTR,HIV-1
R4891 T6200 T6201 arg1Of LTR,lacking
R4892 T6204 T6201 arg2Of sites,lacking
R4893 T6204 T6202 arg1Of sites,the
R4894 T6204 T6203 arg1Of sites,NF-κB
R4895 T6204 T6205 arg1Of sites,located
R4896 T6205 T6206 arg1Of located,between
R4897 T6207 T6208 arg1Of −102,and
R4898 T6208 T6206 arg2Of and,between
R4899 T6208 T6210 arg1Of and,(
R4900 T6208 T6215 arg1Of and,(
R4901 T6209 T6208 arg2Of −81,and
R4902 T6213 T6210 arg2Of LTR,(
R4903 T6213 T6211 arg1Of LTR,HIV-1
R4904 T6213 T6212 arg1Of LTR,Δ-κB
R4905 T6214 T6210 arg3Of ),(
R4906 T6217 T6215 arg2Of 3C,(
R4907 T6217 T6216 arg1Of 3C,Figure
R4908 T6218 T6215 arg3Of ),(
R4909 T6223 T6219 arg1Of construct,This
R4910 T6223 T6220 arg1Of construct,mutant
R4911 T6223 T6221 arg1Of construct,HIV-1
R4912 T6223 T6222 arg1Of construct,LTR
R4913 T6223 T6224 arg1Of construct,exhibited
R4914 T6224 T6229 arg1Of exhibited,compared
R4915 T6226 T6224 arg2Of levels,exhibited
R4916 T6226 T6225 arg2Of levels,reduced
R4917 T6226 T6227 arg1Of levels,of
R4918 T6228 T6227 arg2Of transcription,of
R4919 T6230 T6229 arg2Of to,compared
R4920 T6234 T6230 arg2Of LTR,to
R4921 T6234 T6231 arg1Of LTR,the
R4922 T6234 T6232 arg1Of LTR,parental
R4923 T6234 T6233 arg1Of LTR,HIV-1
R4924 T6234 T6235 arg1Of LTR,in
R4925 T6241 T6235 arg2Of cells,in
R4926 T6241 T6236 arg2Of cells,purified
R4927 T6241 T6237 arg1Of cells,healthy
R4928 T6241 T6238 arg1Of cells,donor
R4929 T6241 T6239 arg1Of cells,CD4+
R4930 T6241 T6240 arg1Of cells,T
R4931 T6241 T6242 arg1Of cells,(
R4932 T6244 T6242 arg2Of data,(
R4933 T6244 T6243 arg1Of data,unpublished
R4934 T6245 T6242 arg3Of ),(
R4935 T6249 T6263 arg1Of comparing,demonstrated
R4936 T6251 T6249 arg2Of effect,comparing
R4937 T6251 T6250 arg1Of effect,the
R4938 T6251 T6252 arg1Of effect,of
R4939 T6251 T6255 arg1Of effect,on
R4940 T6254 T6252 arg2Of overexpression,of
R4941 T6254 T6253 arg1Of overexpression,Foxp3
R4942 T6257 T6255 arg2Of activation,on
R4943 T6257 T6256 arg1Of activation,the
R4944 T6257 T6258 arg1Of activation,of
R4945 T6262 T6258 arg2Of promoters,of
R4946 T6262 T6259 arg1Of promoters,these
R4947 T6262 T6260 arg1Of promoters,two
R4948 T6262 T6261 arg1Of promoters,viral
R4949 T6263 T6246 arg1Of demonstrated,However
R4950 T6263 T6247 arg1Of demonstrated,","
R4951 T6263 T6248 arg1Of demonstrated,directly
R4952 T6265 T6266 arg1Of Foxp3,was
R4953 T6265 T6268 arg1Of Foxp3,capable
R4954 T6265 T6270 arg1Of Foxp3,suppressing
R4955 T6266 T6263 arg2Of was,demonstrated
R4956 T6266 T6264 arg1Of was,that
R4957 T6268 T6266 arg2Of capable,was
R4958 T6268 T6267 arg1Of capable,more
R4959 T6268 T6269 arg1Of capable,of
R4960 T6270 T6269 arg2Of suppressing,of
R4961 T6270 T6281 arg1Of suppressing,compared
R4962 T6272 T6270 arg2Of activation,suppressing
R4963 T6272 T6271 arg1Of activation,transcriptional
R4964 T6272 T6273 arg1Of activation,of
R4965 T6276 T6273 arg2Of LTR,of
R4966 T6276 T6274 arg1Of LTR,the
R4967 T6276 T6275 arg1Of LTR,HIV-1
R4968 T6276 T6277 arg1Of LTR,(
R4969 T6279 T6277 arg2Of 3D,(
R4970 T6279 T6278 arg1Of 3D,Figure
R4971 T6280 T6277 arg3Of ),(
R4972 T6282 T6281 arg2Of to,compared
R4973 T6286 T6282 arg2Of LTR,to
R4974 T6286 T6283 arg1Of LTR,the
R4975 T6286 T6284 arg2Of LTR,mutated
R4976 T6286 T6285 arg1Of LTR,HIV-1
R4977 T6286 T6287 arg1Of LTR,(
R4978 T6289 T6287 arg2Of 3E,(
R4979 T6289 T6288 arg1Of 3E,Figure
R4980 T6290 T6287 arg3Of ),(
R4981 T6292 T6291 arg1Of results,These
R4982 T6292 T6293 arg1Of results,suggest
R4983 T6296 T6295 arg1Of down-regulation,Foxp3
R4984 T6296 T6297 arg1Of down-regulation,of
R4985 T6296 T6301 arg1Of down-regulation,was
R4986 T6296 T6302 arg2Of down-regulation,mediated
R4987 T6300 T6297 arg2Of activation,of
R4988 T6300 T6298 arg1Of activation,HIV-1
R4989 T6300 T6299 arg1Of activation,LTR
R4990 T6302 T6293 arg2Of mediated,suggest
R4991 T6302 T6294 arg1Of mediated,that
R4992 T6302 T6301 arg2Of mediated,was
R4993 T6302 T6305 arg1Of mediated,in
R4994 T6304 T6303 arg1Of least,at
R4995 T6305 T6304 arg1Of in,least
R4996 T6306 T6305 arg2Of part,in
R4997 T6311 T6302 arg1Of sites,mediated
R4998 T6311 T6307 arg2Of sites,by
R4999 T6311 T6308 arg1Of sites,cis-acting
R5000 T6311 T6309 arg1Of sites,NF-κB
R5001 T6311 T6310 arg1Of sites,binding
R5002 T6313 T6312 arg1Of levels,Residual
R5003 T6313 T6314 arg1Of levels,of
R5004 T6313 T6323 arg1Of levels,may
R5005 T6313 T6324 arg1Of levels,be
R5006 T6313 T6325 arg1Of levels,due
R5007 T6315 T6314 arg2Of inhibition,of
R5008 T6315 T6316 arg1Of inhibition,of
R5009 T6315 T6321 arg1Of inhibition,by
R5010 T6320 T6316 arg2Of LTR,of
R5011 T6320 T6317 arg1Of LTR,the
R5012 T6320 T6318 arg1Of LTR,HIV-1
R5013 T6320 T6319 arg1Of LTR,Δ-κB
R5014 T6322 T6321 arg2Of Foxp3,by
R5015 T6324 T6323 arg2Of be,may
R5016 T6324 T6340 arg1Of be,[
R5017 T6325 T6324 arg2Of due,be
R5018 T6325 T6326 arg1Of due,to
R5019 T6325 T6331 arg1Of due,upstream
R5020 T6329 T6326 arg2Of sites,to
R5021 T6329 T6327 arg1Of sites,NF-AT
R5022 T6329 T6328 arg1Of sites,binding
R5023 T6329 T6330 arg1Of sites,located
R5024 T6331 T6332 arg1Of upstream,of
R5025 T6335 T6332 arg2Of sites,of
R5026 T6335 T6333 arg1Of sites,the
R5027 T6335 T6334 arg1Of sites,NF-κB
R5028 T6335 T6336 arg1Of sites,within
R5029 T6339 T6336 arg2Of LTR,within
R5030 T6339 T6337 arg1Of LTR,the
R5031 T6339 T6338 arg1Of LTR,HIV-1
R5032 T6341 T6340 arg2Of "22,23",[
R5033 T6342 T6340 arg3Of ],[

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T5647 0-5 CD denotes Foxp3
T5648 6-16 NNPS denotes Suppresses
T5649 17-22 NNP denotes HIV-1
T5650 23-27 NNP denotes Gene
T5651 28-38 NNP denotes Expression
T5652 39-41 IN denotes in
T5653 42-46 NNP denotes Part
T5654 47-54 IN denotes through
T5655 55-63 NNP denotes Blocking
T5656 64-74 NNP denotes Activation
T5657 75-77 IN denotes of
T5658 78-83 NNP denotes NF-κB
T5659 84-86 IN denotes If
T5660 87-92 JJ denotes Foxp3
T5661 93-102 NNS denotes functions
T5662 103-105 IN denotes as
T5663 106-107 DT denotes a
T5664 108-117 NN denotes repressor
T5665 118-120 IN denotes of
T5666 121-136 JJ denotes NF-κB-dependent
T5667 137-141 NN denotes gene
T5668 142-152 NN denotes expression
T5669 152-153 , denotes ,
T5670 154-158 RB denotes then
T5671 159-161 PRP denotes we
T5672 162-174 VBD denotes hypothesized
T5673 175-179 IN denotes that
T5674 180-185 JJ denotes Foxp3
T5675 186-200 NN denotes overexpression
T5676 201-206 MD denotes could
T5677 207-218 RB denotes selectively
T5678 219-232 JJ denotes down-regulate
T5679 233-246 NN denotes transcription
T5680 247-251 IN denotes from
T5681 252-261 NNS denotes promoters
T5682 262-272 RB denotes previously
T5683 273-278 VBN denotes shown
T5684 279-281 TO denotes to
T5685 282-284 VB denotes be
T5686 285-295 JJ denotes responsive
T5687 296-298 TO denotes to
T5688 299-304 NNP denotes NF-κB
T5689 304-305 . denotes .
T5690 306-308 TO denotes To
T5691 309-316 VB denotes address
T5692 317-321 DT denotes this
T5693 322-330 NN denotes question
T5694 330-331 , denotes ,
T5695 332-334 PRP denotes we
T5696 335-343 VBD denotes examined
T5697 344-347 DT denotes the
T5698 348-363 JJ denotes transcriptional
T5699 364-374 NN denotes activation
T5700 375-377 IN denotes of
T5701 378-381 DT denotes the
T5702 382-387 NNP denotes HIV-1
T5703 388-391 NNP denotes LTR
T5704 391-392 , denotes ,
T5705 393-398 WDT denotes which
T5706 399-407 VBZ denotes contains
T5707 408-411 CD denotes two
T5708 412-418 NN denotes tandem
T5709 419-429 JJ denotes cis-acting
T5710 430-435 NN denotes NF-κB
T5711 436-443 JJ denotes binding
T5712 444-449 NNS denotes sites
T5713 450-457 VBN denotes located
T5714 458-465 IN denotes between
T5715 466-475 NNS denotes positions
T5716 476-477 VBP denotes −
T5717 477-480 CD denotes 102
T5718 481-484 CC denotes and
T5719 485-486 CD denotes −
T5720 486-488 CD denotes 81
T5721 489-493 IN denotes with
T5722 494-501 NN denotes respect
T5723 502-504 TO denotes to
T5724 505-508 DT denotes the
T5725 509-522 NN denotes transcription
T5726 523-533 NN denotes initiation
T5727 534-538 NN denotes site
T5728 539-540 NNP denotes [
T5729 540-542 CD denotes 21
T5730 542-543 NNP denotes ]
T5731 543-544 . denotes .
T5732 545-550 JJ denotes NF-κB
T5733 551-556 NNS denotes plays
T5734 557-558 DT denotes a
T5735 559-566 JJ denotes crucial
T5736 567-571 NN denotes role
T5737 572-574 IN denotes in
T5738 575-585 VBG denotes regulating
T5739 586-590 NN denotes gene
T5740 591-601 NN denotes expression
T5741 602-610 VBD denotes directed
T5742 611-615 IN denotes from
T5743 616-619 DT denotes the
T5744 620-625 NNP denotes HIV-1
T5745 626-629 NNP denotes LTR
T5746 630-632 IN denotes in
T5747 633-636 NNP denotes CD4
T5748 636-637 NNP denotes +
T5749 638-639 NNP denotes T
T5750 640-645 NNS denotes cells
T5751 646-647 NNP denotes [
T5752 647-649 CD denotes 21
T5753 649-650 NNP denotes ]
T5754 650-651 . denotes .
T5755 652-666 NNP denotes Overexpression
T5756 667-669 IN denotes of
T5757 670-681 JJ denotes full-length
T5758 682-687 NNP denotes Foxp3
T5759 687-688 , denotes ,
T5760 689-692 CC denotes but
T5761 693-696 RB denotes not
T5762 697-701 NNP denotes ΔFKH
T5763 701-702 , denotes ,
T5764 703-705 IN denotes in
T5765 706-709 NNP denotes HEK
T5766 710-714 CD denotes 293T
T5767 715-720 NNS denotes cells
T5768 721-724 VBD denotes was
T5769 725-729 JJ denotes able
T5770 730-732 TO denotes to
T5771 733-740 VB denotes inhibit
T5772 741-746 JJ denotes basal
T5773 747-757 NN denotes activation
T5774 758-760 IN denotes of
T5775 761-764 DT denotes the
T5776 765-770 NNP denotes HIV-1
T5777 771-774 NNP denotes LTR
T5778 775-776 -LRB- denotes (
T5779 776-782 NNP denotes Figure
T5780 783-785 NNP denotes 3A
T5781 785-786 -RRB- denotes )
T5782 786-787 , denotes ,
T5783 788-795 JJ denotes similar
T5784 796-798 TO denotes to
T5785 799-803 WP denotes what
T5786 804-807 VBD denotes was
T5787 808-818 RB denotes previously
T5788 819-831 VBN denotes demonstrated
T5789 832-836 IN denotes with
T5790 837-840 DT denotes the
T5791 841-850 JJ denotes synthetic
T5792 851-856 NN denotes NF-κB
T5793 857-865 NN denotes reporter
T5794 866-872 NN denotes vector
T5795 873-874 -LRB- denotes (
T5796 874-880 NN denotes Figure
T5797 881-883 NN denotes 2B
T5798 883-884 -RRB- denotes )
T5799 884-885 . denotes .
T5800 886-897 RB denotes Furthermore
T5801 897-898 , denotes ,
T5802 899-904 NNP denotes HIV-1
T5803 905-908 NNP denotes LTR
T5804 909-919 NN denotes activation
T5805 920-923 VBD denotes was
T5806 924-934 VBN denotes suppressed
T5807 935-937 IN denotes by
T5808 938-949 JJ denotes full-length
T5809 950-955 NNP denotes Foxp3
T5810 956-959 CC denotes and
T5811 960-964 NNP denotes ΔFKH
T5812 965-967 IN denotes in
T5813 968-974 NNP denotes Jurkat
T5814 975-976 NNP denotes T
T5815 977-982 NNS denotes cells
T5816 983-984 -LRB- denotes (
T5817 984-990 NN denotes Figure
T5818 991-993 NN denotes 3B
T5819 993-994 -RRB- denotes )
T5820 994-995 . denotes .
T5821 996-998 TO denotes To
T5822 999-1010 VB denotes demonstrate
T5823 1011-1015 DT denotes that
T5824 1016-1030 JJ denotes Foxp3-mediated
T5825 1031-1036 NN denotes HIV-1
T5826 1037-1040 NNP denotes LTR
T5827 1041-1051 NN denotes repression
T5828 1052-1055 VBD denotes was
T5829 1056-1066 VBN denotes associated
T5830 1067-1071 IN denotes with
T5831 1072-1084 NNS denotes interactions
T5832 1085-1089 IN denotes with
T5833 1090-1095 JJ denotes NF-κB
T5834 1096-1101 VBN denotes bound
T5835 1102-1104 TO denotes to
T5836 1105-1108 DT denotes the
T5837 1109-1114 NNP denotes HIV-1
T5838 1115-1118 NNP denotes LTR
T5839 1118-1119 , denotes ,
T5840 1120-1122 PRP denotes we
T5841 1123-1131 VBD denotes compared
T5842 1132-1137 JJ denotes basal
T5843 1138-1148 NN denotes activation
T5844 1149-1151 IN denotes of
T5845 1152-1155 DT denotes the
T5846 1156-1161 NNP denotes HIV-1
T5847 1162-1165 NNP denotes LTR
T5848 1166-1168 CC denotes or
T5849 1169-1171 DT denotes an
T5850 1172-1181 JJ denotes identical
T5851 1182-1187 NNP denotes HIV-1
T5852 1188-1191 NNP denotes LTR
T5853 1192-1199 VBG denotes lacking
T5854 1200-1203 DT denotes the
T5855 1204-1209 JJ denotes NF-κB
T5856 1210-1215 NNS denotes sites
T5857 1216-1223 VBN denotes located
T5858 1224-1231 IN denotes between
T5859 1232-1233 CD denotes −
T5860 1233-1236 CD denotes 102
T5861 1237-1240 CC denotes and
T5862 1241-1242 CD denotes −
T5863 1242-1244 CD denotes 81
T5864 1245-1246 -LRB- denotes (
T5865 1246-1251 NN denotes HIV-1
T5866 1252-1256 NN denotes Δ-κB
T5867 1257-1260 NNP denotes LTR
T5868 1260-1261 -RRB- denotes )
T5869 1262-1263 -LRB- denotes (
T5870 1263-1269 NN denotes Figure
T5871 1270-1272 NN denotes 3C
T5872 1272-1273 -RRB- denotes )
T5873 1273-1274 . denotes .
T5874 1275-1279 DT denotes This
T5875 1280-1286 JJ denotes mutant
T5876 1287-1292 NNP denotes HIV-1
T5877 1293-1296 NNP denotes LTR
T5878 1297-1306 VBP denotes construct
T5879 1307-1316 VBN denotes exhibited
T5880 1317-1324 JJ denotes reduced
T5881 1325-1331 NNS denotes levels
T5882 1332-1334 IN denotes of
T5883 1335-1348 NN denotes transcription
T5884 1349-1357 VBN denotes compared
T5885 1358-1360 TO denotes to
T5886 1361-1364 DT denotes the
T5887 1365-1373 JJ denotes parental
T5888 1374-1379 NNP denotes HIV-1
T5889 1380-1383 NNP denotes LTR
T5890 1384-1386 IN denotes in
T5891 1387-1395 JJ denotes purified
T5892 1396-1403 JJ denotes healthy
T5893 1404-1409 NN denotes donor
T5894 1410-1413 NNP denotes CD4
T5895 1413-1414 NNP denotes +
T5896 1415-1416 NNP denotes T
T5897 1417-1422 NNS denotes cells
T5898 1423-1424 -LRB- denotes (
T5899 1424-1435 JJ denotes unpublished
T5900 1436-1440 NNS denotes data
T5901 1440-1441 -RRB- denotes )
T5902 1441-1442 . denotes .
T5903 1443-1450 RB denotes However
T5904 1450-1451 , denotes ,
T5905 1452-1460 RB denotes directly
T5906 1461-1470 VBG denotes comparing
T5907 1471-1474 DT denotes the
T5908 1475-1481 NN denotes effect
T5909 1482-1484 IN denotes of
T5910 1485-1490 JJ denotes Foxp3
T5911 1491-1505 NN denotes overexpression
T5912 1506-1508 IN denotes on
T5913 1509-1512 DT denotes the
T5914 1513-1523 NN denotes activation
T5915 1524-1526 IN denotes of
T5916 1527-1532 DT denotes these
T5917 1533-1536 CD denotes two
T5918 1537-1542 JJ denotes viral
T5919 1543-1552 NNS denotes promoters
T5920 1553-1565 VBD denotes demonstrated
T5921 1566-1570 IN denotes that
T5922 1571-1576 NNP denotes Foxp3
T5923 1577-1580 VBD denotes was
T5924 1581-1585 RBR denotes more
T5925 1586-1593 JJ denotes capable
T5926 1594-1596 IN denotes of
T5927 1597-1608 VBG denotes suppressing
T5928 1609-1624 JJ denotes transcriptional
T5929 1625-1635 NN denotes activation
T5930 1636-1638 IN denotes of
T5931 1639-1642 DT denotes the
T5932 1643-1648 NNP denotes HIV-1
T5933 1649-1652 NNP denotes LTR
T5934 1653-1654 -LRB- denotes (
T5935 1654-1660 NNP denotes Figure
T5936 1661-1663 NNP denotes 3D
T5937 1663-1664 -RRB- denotes )
T5938 1665-1673 VBN denotes compared
T5939 1674-1676 TO denotes to
T5940 1677-1680 DT denotes the
T5941 1681-1688 VBN denotes mutated
T5942 1689-1694 NNP denotes HIV-1
T5943 1695-1698 NNP denotes LTR
T5944 1699-1700 -LRB- denotes (
T5945 1700-1706 NNP denotes Figure
T5946 1707-1709 NNP denotes 3E
T5947 1709-1710 -RRB- denotes )
T5948 1710-1711 . denotes .
T5949 1712-1717 DT denotes These
T5950 1718-1725 NNS denotes results
T5951 1726-1733 VBP denotes suggest
T5952 1734-1738 IN denotes that
T5953 1739-1744 JJ denotes Foxp3
T5954 1745-1760 NN denotes down-regulation
T5955 1761-1763 IN denotes of
T5956 1764-1769 NNP denotes HIV-1
T5957 1770-1773 NNP denotes LTR
T5958 1774-1784 NN denotes activation
T5959 1785-1788 VBD denotes was
T5960 1789-1797 VBN denotes mediated
T5961 1798-1800 IN denotes at
T5962 1801-1806 JJS denotes least
T5963 1807-1809 IN denotes in
T5964 1810-1814 NN denotes part
T5965 1815-1817 IN denotes by
T5966 1818-1828 JJ denotes cis-acting
T5967 1829-1834 JJ denotes NF-κB
T5968 1835-1842 JJ denotes binding
T5969 1843-1848 NNS denotes sites
T5970 1848-1849 . denotes .
T5971 1850-1858 JJ denotes Residual
T5972 1859-1865 NNS denotes levels
T5973 1866-1868 IN denotes of
T5974 1869-1879 NN denotes inhibition
T5975 1880-1882 IN denotes of
T5976 1883-1886 DT denotes the
T5977 1887-1892 NNP denotes HIV-1
T5978 1893-1897 NNP denotes Δ-κB
T5979 1898-1901 NNP denotes LTR
T5980 1902-1904 IN denotes by
T5981 1905-1910 NNP denotes Foxp3
T5982 1911-1914 MD denotes may
T5983 1915-1917 VB denotes be
T5984 1918-1921 JJ denotes due
T5985 1922-1924 TO denotes to
T5986 1925-1930 NNP denotes NF-AT
T5987 1931-1938 JJ denotes binding
T5988 1939-1944 NNS denotes sites
T5989 1945-1952 VBN denotes located
T5990 1953-1961 RB denotes upstream
T5991 1962-1964 IN denotes of
T5992 1965-1968 DT denotes the
T5993 1969-1974 NNP denotes NF-κB
T5994 1975-1980 NNS denotes sites
T5995 1981-1987 IN denotes within
T5996 1988-1991 DT denotes the
T5997 1992-1997 NNP denotes HIV-1
T5998 1998-2001 NNP denotes LTR
T5999 2002-2003 NNP denotes [
T6000 2003-2008 CD denotes 22,23
T6001 2008-2009 NNP denotes ]
T6002 2009-2010 . denotes .
R4334 T5647 T5648 nummod Foxp3,Suppresses
R4335 T5648 T5648 ROOT Suppresses,Suppresses
R4336 T5649 T5651 compound HIV-1,Expression
R4337 T5650 T5651 compound Gene,Expression
R4338 T5651 T5648 dobj Expression,Suppresses
R4339 T5652 T5651 prep in,Expression
R4340 T5653 T5652 pobj Part,in
R4341 T5654 T5648 prep through,Suppresses
R4342 T5655 T5656 amod Blocking,Activation
R4343 T5656 T5654 pobj Activation,through
R4344 T5657 T5656 prep of,Activation
R4345 T5658 T5657 pobj NF-κB,of
R4346 T5659 T5672 mark If,hypothesized
R4347 T5660 T5661 amod Foxp3,functions
R4348 T5661 T5672 nsubj functions,hypothesized
R4349 T5662 T5661 prep as,functions
R4350 T5663 T5664 det a,repressor
R4351 T5664 T5662 pobj repressor,as
R4352 T5665 T5664 prep of,repressor
R4353 T5666 T5668 amod NF-κB-dependent,expression
R4354 T5667 T5668 compound gene,expression
R4355 T5668 T5665 pobj expression,of
R4356 T5669 T5672 punct ",",hypothesized
R4357 T5670 T5672 advmod then,hypothesized
R4358 T5671 T5672 nsubj we,hypothesized
R4359 T5672 T5689 advcl hypothesized,.
R4360 T5673 T5679 mark that,transcription
R4361 T5674 T5675 amod Foxp3,overexpression
R4362 T5675 T5679 nsubj overexpression,transcription
R4363 T5676 T5679 aux could,transcription
R4364 T5677 T5678 advmod selectively,down-regulate
R4365 T5678 T5679 nsubj down-regulate,transcription
R4366 T5679 T5672 ccomp transcription,hypothesized
R4367 T5680 T5679 prep from,transcription
R4368 T5681 T5680 pobj promoters,from
R4369 T5682 T5683 advmod previously,shown
R4370 T5683 T5681 acl shown,promoters
R4371 T5684 T5685 aux to,be
R4372 T5685 T5683 xcomp be,shown
R4373 T5686 T5685 acomp responsive,be
R4374 T5687 T5686 prep to,responsive
R4375 T5688 T5687 pobj NF-κB,to
R4376 T5689 T5648 punct .,Suppresses
R4377 T5690 T5691 aux To,address
R4378 T5691 T5696 advcl address,examined
R4379 T5692 T5693 det this,question
R4380 T5693 T5691 dobj question,address
R4381 T5694 T5696 punct ",",examined
R4382 T5695 T5696 nsubj we,examined
R4383 T5696 T5696 ROOT examined,examined
R4384 T5697 T5699 det the,activation
R4385 T5698 T5699 amod transcriptional,activation
R4386 T5699 T5696 dobj activation,examined
R4387 T5700 T5699 prep of,activation
R4388 T5701 T5703 det the,LTR
R4389 T5702 T5703 compound HIV-1,LTR
R4390 T5703 T5700 pobj LTR,of
R4391 T5704 T5703 punct ",",LTR
R4392 T5705 T5706 nsubj which,contains
R4393 T5706 T5699 relcl contains,activation
R4394 T5707 T5712 nummod two,sites
R4395 T5708 T5710 nmod tandem,NF-κB
R4396 T5709 T5710 amod cis-acting,NF-κB
R4397 T5710 T5712 amod NF-κB,sites
R4398 T5711 T5712 amod binding,sites
R4399 T5712 T5706 dobj sites,contains
R4400 T5713 T5712 acl located,sites
R4401 T5714 T5713 prep between,located
R4402 T5715 T5714 pobj positions,between
R4403 T5716 T5696 oprd −,examined
R4404 T5717 T5716 nummod 102,−
R4405 T5718 T5716 cc and,−
R4406 T5719 T5720 nummod −,81
R4407 T5720 T5716 conj 81,−
R4408 T5721 T5716 prep with,−
R4409 T5722 T5721 pobj respect,with
R4410 T5723 T5722 prep to,respect
R4411 T5724 T5727 det the,site
R4412 T5725 T5726 compound transcription,initiation
R4413 T5726 T5727 compound initiation,site
R4414 T5727 T5723 pobj site,to
R4415 T5728 T5727 appos [,site
R4416 T5729 T5730 nummod 21,]
R4417 T5730 T5727 appos ],site
R4418 T5731 T5696 punct .,examined
R4419 T5732 T5733 amod NF-κB,plays
R4420 T5733 T5733 ROOT plays,plays
R4421 T5734 T5736 det a,role
R4422 T5735 T5736 amod crucial,role
R4423 T5736 T5733 dobj role,plays
R4424 T5737 T5736 prep in,role
R4425 T5738 T5737 pcomp regulating,in
R4426 T5739 T5740 compound gene,expression
R4427 T5740 T5738 dobj expression,regulating
R4428 T5741 T5736 acl directed,role
R4429 T5742 T5741 prep from,directed
R4430 T5743 T5745 det the,LTR
R4431 T5744 T5745 compound HIV-1,LTR
R4432 T5745 T5742 pobj LTR,from
R4433 T5746 T5745 prep in,LTR
R4434 T5747 T5746 pobj CD4,in
R4435 T5748 T5750 amod +,cells
R4436 T5749 T5750 compound T,cells
R4437 T5750 T5741 dobj cells,directed
R4438 T5751 T5750 appos [,cells
R4439 T5752 T5753 nummod 21,]
R4440 T5753 T5751 appos ],[
R4441 T5754 T5733 punct .,plays
R4442 T5755 T5768 nsubj Overexpression,was
R4443 T5756 T5755 prep of,Overexpression
R4444 T5757 T5758 amod full-length,Foxp3
R4445 T5758 T5756 pobj Foxp3,of
R4446 T5759 T5755 punct ",",Overexpression
R4447 T5760 T5755 cc but,Overexpression
R4448 T5761 T5760 neg not,but
R4449 T5762 T5755 conj ΔFKH,Overexpression
R4450 T5763 T5768 punct ",",was
R4451 T5764 T5768 prep in,was
R4452 T5765 T5764 pobj HEK,in
R4453 T5766 T5767 nummod 293T,cells
R4454 T5767 T5768 nsubj cells,was
R4455 T5768 T5768 ROOT was,was
R4456 T5769 T5768 acomp able,was
R4457 T5770 T5771 aux to,inhibit
R4458 T5771 T5769 xcomp inhibit,able
R4459 T5772 T5773 amod basal,activation
R4460 T5773 T5771 dobj activation,inhibit
R4461 T5774 T5773 prep of,activation
R4462 T5775 T5777 det the,LTR
R4463 T5776 T5777 compound HIV-1,LTR
R4464 T5777 T5774 pobj LTR,of
R4465 T5778 T5780 punct (,3A
R4466 T5779 T5780 compound Figure,3A
R4467 T5780 T5777 appos 3A,LTR
R4468 T5781 T5777 punct ),LTR
R4469 T5782 T5777 punct ",",LTR
R4470 T5783 T5773 amod similar,activation
R4471 T5784 T5783 prep to,similar
R4472 T5785 T5788 nsubjpass what,demonstrated
R4473 T5786 T5788 auxpass was,demonstrated
R4474 T5787 T5788 advmod previously,demonstrated
R4475 T5788 T5784 pcomp demonstrated,to
R4476 T5789 T5788 prep with,demonstrated
R4477 T5790 T5794 det the,vector
R4478 T5791 T5793 amod synthetic,reporter
R4479 T5792 T5793 compound NF-κB,reporter
R4480 T5793 T5794 compound reporter,vector
R4481 T5794 T5789 pobj vector,with
R4482 T5795 T5797 punct (,2B
R4483 T5796 T5797 compound Figure,2B
R4484 T5797 T5794 appos 2B,vector
R4485 T5798 T5797 punct ),2B
R4486 T5799 T5768 punct .,was
R4487 T5800 T5806 advmod Furthermore,suppressed
R4488 T5801 T5806 punct ",",suppressed
R4489 T5802 T5804 compound HIV-1,activation
R4490 T5803 T5804 compound LTR,activation
R4491 T5804 T5806 nsubjpass activation,suppressed
R4492 T5805 T5806 auxpass was,suppressed
R4493 T5806 T5806 ROOT suppressed,suppressed
R4494 T5807 T5806 agent by,suppressed
R4495 T5808 T5809 amod full-length,Foxp3
R4496 T5809 T5807 pobj Foxp3,by
R4497 T5810 T5809 cc and,Foxp3
R4498 T5811 T5809 conj ΔFKH,Foxp3
R4499 T5812 T5806 prep in,suppressed
R4500 T5813 T5814 compound Jurkat,T
R4501 T5814 T5815 compound T,cells
R4502 T5815 T5812 pobj cells,in
R4503 T5816 T5818 punct (,3B
R4504 T5817 T5818 compound Figure,3B
R4505 T5818 T5815 appos 3B,cells
R4506 T5819 T5806 punct ),suppressed
R4507 T5820 T5806 punct .,suppressed
R4508 T5821 T5822 aux To,demonstrate
R4509 T5822 T5829 advcl demonstrate,associated
R4510 T5823 T5827 det that,repression
R4511 T5824 T5827 amod Foxp3-mediated,repression
R4512 T5825 T5827 compound HIV-1,repression
R4513 T5826 T5827 compound LTR,repression
R4514 T5827 T5829 nsubjpass repression,associated
R4515 T5828 T5829 auxpass was,associated
R4516 T5829 T5829 ROOT associated,associated
R4517 T5830 T5829 prep with,associated
R4518 T5831 T5830 pobj interactions,with
R4519 T5832 T5831 prep with,interactions
R4520 T5833 T5834 amod NF-κB,bound
R4521 T5834 T5829 conj bound,associated
R4522 T5835 T5834 prep to,bound
R4523 T5836 T5838 det the,LTR
R4524 T5837 T5838 compound HIV-1,LTR
R4525 T5838 T5835 pobj LTR,to
R4526 T5839 T5841 punct ",",compared
R4527 T5840 T5841 nsubj we,compared
R4528 T5841 T5841 ROOT compared,compared
R4529 T5842 T5843 amod basal,activation
R4530 T5843 T5841 dobj activation,compared
R4531 T5844 T5843 prep of,activation
R4532 T5845 T5847 det the,LTR
R4533 T5846 T5847 compound HIV-1,LTR
R4534 T5847 T5844 pobj LTR,of
R4535 T5848 T5847 cc or,LTR
R4536 T5849 T5852 det an,LTR
R4537 T5850 T5852 amod identical,LTR
R4538 T5851 T5852 compound HIV-1,LTR
R4539 T5852 T5847 conj LTR,LTR
R4540 T5853 T5841 advcl lacking,compared
R4541 T5854 T5856 det the,sites
R4542 T5855 T5856 amod NF-κB,sites
R4543 T5856 T5853 dobj sites,lacking
R4544 T5857 T5856 acl located,sites
R4545 T5858 T5857 prep between,located
R4546 T5859 T5858 pobj −,between
R4547 T5860 T5859 conj 102,−
R4548 T5861 T5860 cc and,102
R4549 T5862 T5863 nummod −,81
R4550 T5863 T5860 conj 81,102
R4551 T5864 T5867 punct (,LTR
R4552 T5865 T5867 compound HIV-1,LTR
R4553 T5866 T5867 compound Δ-κB,LTR
R4554 T5867 T5859 appos LTR,−
R4555 T5868 T5859 punct ),−
R4556 T5869 T5871 punct (,3C
R4557 T5870 T5871 nmod Figure,3C
R4558 T5871 T5859 appos 3C,−
R4559 T5872 T5859 punct ),−
R4560 T5873 T5841 punct .,compared
R4561 T5874 T5877 det This,LTR
R4562 T5875 T5877 amod mutant,LTR
R4563 T5876 T5877 compound HIV-1,LTR
R4564 T5877 T5878 nsubj LTR,construct
R4565 T5878 T5878 ROOT construct,construct
R4566 T5879 T5881 amod exhibited,levels
R4567 T5880 T5881 amod reduced,levels
R4568 T5881 T5884 nsubj levels,compared
R4569 T5882 T5881 prep of,levels
R4570 T5883 T5882 pobj transcription,of
R4571 T5884 T5878 ccomp compared,construct
R4572 T5885 T5884 prep to,compared
R4573 T5886 T5889 det the,LTR
R4574 T5887 T5889 amod parental,LTR
R4575 T5888 T5889 compound HIV-1,LTR
R4576 T5889 T5885 pobj LTR,to
R4577 T5890 T5889 prep in,LTR
R4578 T5891 T5893 amod purified,donor
R4579 T5892 T5893 amod healthy,donor
R4580 T5893 T5897 compound donor,cells
R4581 T5894 T5897 compound CD4,cells
R4582 T5895 T5897 compound +,cells
R4583 T5896 T5897 compound T,cells
R4584 T5897 T5890 pobj cells,in
R4585 T5898 T5897 punct (,cells
R4586 T5899 T5900 amod unpublished,data
R4587 T5900 T5897 appos data,cells
R4588 T5901 T5897 punct ),cells
R4589 T5902 T5878 punct .,construct
R4590 T5903 T5920 advmod However,demonstrated
R4591 T5904 T5920 punct ",",demonstrated
R4592 T5905 T5906 advmod directly,comparing
R4593 T5906 T5920 csubj comparing,demonstrated
R4594 T5907 T5908 det the,effect
R4595 T5908 T5906 dobj effect,comparing
R4596 T5909 T5908 prep of,effect
R4597 T5910 T5911 amod Foxp3,overexpression
R4598 T5911 T5909 pobj overexpression,of
R4599 T5912 T5911 prep on,overexpression
R4600 T5913 T5914 det the,activation
R4601 T5914 T5912 pobj activation,on
R4602 T5915 T5914 prep of,activation
R4603 T5916 T5919 det these,promoters
R4604 T5917 T5919 nummod two,promoters
R4605 T5918 T5919 amod viral,promoters
R4606 T5919 T5915 pobj promoters,of
R4607 T5920 T5920 ROOT demonstrated,demonstrated
R4608 T5921 T5923 mark that,was
R4609 T5922 T5923 nsubj Foxp3,was
R4610 T5923 T5920 ccomp was,demonstrated
R4611 T5924 T5925 advmod more,capable
R4612 T5925 T5923 acomp capable,was
R4613 T5926 T5925 prep of,capable
R4614 T5927 T5926 pcomp suppressing,of
R4615 T5928 T5929 amod transcriptional,activation
R4616 T5929 T5927 dobj activation,suppressing
R4617 T5930 T5929 prep of,activation
R4618 T5931 T5933 det the,LTR
R4619 T5932 T5933 compound HIV-1,LTR
R4620 T5933 T5930 pobj LTR,of
R4621 T5934 T5936 punct (,3D
R4622 T5935 T5936 compound Figure,3D
R4623 T5936 T5933 appos 3D,LTR
R4624 T5937 T5933 punct ),LTR
R4625 T5938 T5923 prep compared,was
R4626 T5939 T5938 prep to,compared
R4627 T5940 T5943 det the,LTR
R4628 T5941 T5943 amod mutated,LTR
R4629 T5942 T5943 compound HIV-1,LTR
R4630 T5943 T5939 pobj LTR,to
R4631 T5944 T5946 punct (,3E
R4632 T5945 T5946 compound Figure,3E
R4633 T5946 T5943 appos 3E,LTR
R4634 T5947 T5946 punct ),3E
R4635 T5948 T5920 punct .,demonstrated
R4636 T5949 T5950 det These,results
R4637 T5950 T5951 nsubj results,suggest
R4638 T5951 T5951 ROOT suggest,suggest
R4639 T5952 T5960 mark that,mediated
R4640 T5953 T5954 amod Foxp3,down-regulation
R4641 T5954 T5960 nsubjpass down-regulation,mediated
R4642 T5955 T5954 prep of,down-regulation
R4643 T5956 T5957 compound HIV-1,LTR
R4644 T5957 T5958 compound LTR,activation
R4645 T5958 T5955 pobj activation,of
R4646 T5959 T5960 auxpass was,mediated
R4647 T5960 T5951 ccomp mediated,suggest
R4648 T5961 T5962 advmod at,least
R4649 T5962 T5963 advmod least,in
R4650 T5963 T5960 prep in,mediated
R4651 T5964 T5963 pobj part,in
R4652 T5965 T5960 agent by,mediated
R4653 T5966 T5969 amod cis-acting,sites
R4654 T5967 T5969 amod NF-κB,sites
R4655 T5968 T5969 amod binding,sites
R4656 T5969 T5965 pobj sites,by
R4657 T5970 T5951 punct .,suggest
R4658 T5971 T5972 amod Residual,levels
R4659 T5972 T5983 nsubj levels,be
R4660 T5973 T5972 prep of,levels
R4661 T5974 T5973 pobj inhibition,of
R4662 T5975 T5974 prep of,inhibition
R4663 T5976 T5979 det the,LTR
R4664 T5977 T5979 compound HIV-1,LTR
R4665 T5978 T5979 compound Δ-κB,LTR
R4666 T5979 T5975 pobj LTR,of
R4667 T5980 T5972 prep by,levels
R4668 T5981 T5980 pobj Foxp3,by
R4669 T5982 T5983 aux may,be
R4670 T5983 T5983 ROOT be,be
R4671 T5984 T5983 acomp due,be
R4672 T5985 T5984 prep to,due
R4673 T5986 T5988 nmod NF-AT,sites
R4674 T5987 T5988 amod binding,sites
R4675 T5988 T5985 pobj sites,to
R4676 T5989 T5988 acl located,sites
R4677 T5990 T5989 advmod upstream,located
R4678 T5991 T5990 prep of,upstream
R4679 T5992 T5994 det the,sites
R4680 T5993 T5994 compound NF-κB,sites
R4681 T5994 T5991 pobj sites,of
R4682 T5995 T5994 prep within,sites
R4683 T5996 T5999 det the,[
R4684 T5997 T5999 compound HIV-1,[
R4685 T5998 T5999 compound LTR,[
R4686 T5999 T5995 pobj [,within
R4687 T6000 T6001 nummod "22,23",]
R4688 T6001 T5994 conj ],sites
R4689 T6002 T5983 punct .,be

GO-BP

Id Subject Object Predicate Lexical cue
T5639 23-38 http://purl.obolibrary.org/obo/GO_0010467 denotes Gene Expression
T5640 137-152 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T5641 586-601 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T5642 233-246 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T5643 509-522 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T5644 1335-1348 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T5645 1609-1624 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T5646 1750-1760 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation

GO-MF

Id Subject Object Predicate Lexical cue
T6369 430-443 http://purl.obolibrary.org/obo/GO_0051059 denotes NF-κB binding
T6370 1829-1842 http://purl.obolibrary.org/obo/GO_0051059 denotes NF-κB binding
T6371 436-443 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T6372 1835-1842 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T6373 1931-1938 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T6374 1928-1938 http://purl.obolibrary.org/obo/GO_0003680 denotes AT binding

GO-CC

Id Subject Object Predicate Lexical cue
T6375 640-645 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T6376 715-720 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T6377 977-982 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T6378 1417-1422 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

events-check-again

Id Subject Object Predicate Lexical cue Speculation
T6480 0-5 Protein denotes Foxp3
T6481 87-92 Protein denotes Foxp3
T6482 180-185 Protein denotes Foxp3
T6483 186-200 Positive_regulation denotes overexpression
T6484 633-636 Protein denotes CD4
T6485 652-666 Positive_regulation denotes Overexpression
T6486 652-666 Positive_regulation denotes Overexpression
T6487 682-687 Protein denotes Foxp3
T6488 697-701 Protein denotes ΔFKH
T6489 950-955 Protein denotes Foxp3
T6490 960-964 Protein denotes ΔFKH
T6491 1016-1021 Protein denotes Foxp3
T6492 1072-1084 Binding denotes interactions true
T6493 1410-1413 Protein denotes CD4
T6494 1485-1490 Protein denotes Foxp3
T6495 1491-1505 Positive_regulation denotes overexpression
T6496 1571-1576 Protein denotes Foxp3
T6497 1739-1744 Protein denotes Foxp3
T6498 1905-1910 Protein denotes Foxp3
R5064 T6482 T6483 themeOf Foxp3,overexpression
R5065 T6487 T6486 themeOf Foxp3,Overexpression
R5066 T6488 T6485 themeOf ΔFKH,Overexpression
R5067 T6491 T6492 themeOf Foxp3,interactions
R5068 T6494 T6495 themeOf Foxp3,overexpression

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Speculation
T5609 0-5 Protein denotes Foxp3
T5610 87-92 Protein denotes Foxp3
T5611 180-185 Protein denotes Foxp3
T5612 186-200 Positive_regulation denotes overexpression
T5613 633-636 Protein denotes CD4
T5614 652-666 Positive_regulation denotes Overexpression
T5615 652-666 Positive_regulation denotes Overexpression
T5616 682-687 Protein denotes Foxp3
T5617 697-701 Protein denotes ΔFKH
T5618 950-955 Protein denotes Foxp3
T5619 960-964 Protein denotes ΔFKH
T5620 1016-1021 Protein denotes Foxp3
T5621 1072-1084 Binding denotes interactions true
T5622 1410-1413 Protein denotes CD4
T5623 1485-1490 Protein denotes Foxp3
T5624 1491-1505 Positive_regulation denotes overexpression
T5625 1571-1576 Protein denotes Foxp3
T5626 1739-1744 Protein denotes Foxp3
T5627 1905-1910 Protein denotes Foxp3
R4329 T5611 T5612 themeOf Foxp3,overexpression
R4330 T5616 T5615 themeOf Foxp3,Overexpression
R4331 T5617 T5614 themeOf ΔFKH,Overexpression
R4332 T5620 T5621 themeOf Foxp3,interactions
R4333 T5623 T5624 themeOf Foxp3,overexpression

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T6343 0-5 Q9BZS1 denotes Foxp3
T6344 87-92 Q9BZS1 denotes Foxp3
T6345 180-185 Q9BZS1 denotes Foxp3
T6346 633-636 P01730 denotes CD4
T6347 682-687 Q9BZS1 denotes Foxp3
T6348 697-701 P55316 denotes ΔFKH
T6349 725-729 P00519 denotes able
T6350 950-955 Q9BZS1 denotes Foxp3
T6351 960-964 P55316 denotes ΔFKH
T6352 1016-1021 Q9BZS1 denotes Foxp3
T6353 1410-1413 P01730 denotes CD4
T6354 1485-1490 Q9BZS1 denotes Foxp3
T6355 1571-1576 Q9BZS1 denotes Foxp3
T6356 1739-1744 Q9BZS1 denotes Foxp3
T6357 1905-1910 Q9BZS1 denotes Foxp3

test2

Id Subject Object Predicate Lexical cue Speculation
T5589 0-5 Protein denotes Foxp3
T5590 87-92 Protein denotes Foxp3
T5591 180-185 Protein denotes Foxp3
T5592 186-200 Positive_regulation denotes overexpression true
T5593 219-224 Negative_regulation denotes down-
T5594 224-232 Positive_regulation denotes regulate
T5595 633-636 Protein denotes CD4
T5596 652-666 Positive_regulation denotes Overexpression
T5597 682-687 Protein denotes Foxp3
T5598 697-701 Protein denotes ΔFKH
T5599 950-955 Protein denotes Foxp3
T5600 960-964 Protein denotes ΔFKH
T5601 1016-1021 Protein denotes Foxp3
T5602 1410-1413 Protein denotes CD4
T5603 1475-1481 Regulation denotes effect
T5604 1485-1490 Protein denotes Foxp3
T5605 1491-1505 Positive_regulation denotes overexpression
T5606 1571-1576 Protein denotes Foxp3
T5607 1739-1744 Protein denotes Foxp3
T5608 1905-1910 Protein denotes Foxp3
R4325 T5591 T5592 themeOf Foxp3,overexpression
R4326 T5597 T5596 themeOf Foxp3,Overexpression
R4327 T5598 T5596 themeOf ΔFKH,Overexpression
R4328 T5604 T5605 themeOf Foxp3,overexpression